Amino acid dipepetide frequency for Flaviramulus basaltis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.527AlaAla: 3.527 ± 0.072	0.52AlaCys: 0.52 ± 0.023	3.008AlaAsp: 3.008 ± 0.053	3.627AlaGlu: 3.627 ± 0.064	3.256AlaPhe: 3.256 ± 0.052	3.691AlaGly: 3.691 ± 0.071	0.992AlaHis: 0.992 ± 0.027	5.475AlaIle: 5.475 ± 0.079	4.449AlaLys: 4.449 ± 0.082	5.897AlaLeu: 5.897 ± 0.09	1.35AlaMet: 1.35 ± 0.036	3.502AlaAsn: 3.502 ± 0.064	1.689AlaPro: 1.689 ± 0.039	2.048AlaGln: 2.048 ± 0.044	1.676AlaArg: 1.676 ± 0.036	4.195AlaSer: 4.195 ± 0.068	3.481AlaThr: 3.481 ± 0.074	3.559AlaVal: 3.559 ± 0.064	0.589AlaTrp: 0.589 ± 0.022	2.423AlaTyr: 2.423 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.419CysAla: 0.419 ± 0.021	0.098CysCys: 0.098 ± 0.008	0.479CysAsp: 0.479 ± 0.026	0.492CysGlu: 0.492 ± 0.023	0.402CysPhe: 0.402 ± 0.02	0.588CysGly: 0.588 ± 0.028	0.164CysHis: 0.164 ± 0.014	0.617CysIle: 0.617 ± 0.025	0.585CysLys: 0.585 ± 0.022	0.609CysLeu: 0.609 ± 0.021	0.145CysMet: 0.145 ± 0.011	0.474CysAsn: 0.474 ± 0.024	0.307CysPro: 0.307 ± 0.018	0.186CysGln: 0.186 ± 0.012	0.165CysArg: 0.165 ± 0.012	0.543CysSer: 0.543 ± 0.024	0.4CysThr: 0.4 ± 0.025	0.414CysVal: 0.414 ± 0.018	0.064CysTrp: 0.064 ± 0.007	0.303CysTyr: 0.303 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.814AspAla: 3.814 ± 0.078	0.403AspCys: 0.403 ± 0.02	3.302AspAsp: 3.302 ± 0.067	3.743AspGlu: 3.743 ± 0.06	3.779AspPhe: 3.779 ± 0.068	3.768AspGly: 3.768 ± 0.079	0.782AspHis: 0.782 ± 0.027	4.858AspIle: 4.858 ± 0.06	4.184AspLys: 4.184 ± 0.06	5.309AspLeu: 5.309 ± 0.074	1.189AspMet: 1.189 ± 0.034	3.597AspAsn: 3.597 ± 0.067	1.521AspPro: 1.521 ± 0.04	1.173AspGln: 1.173 ± 0.029	1.64AspArg: 1.64 ± 0.034	3.434AspSer: 3.434 ± 0.052	2.806AspThr: 2.806 ± 0.057	3.86AspVal: 3.86 ± 0.061	0.761AspTrp: 0.761 ± 0.025	3.055AspTyr: 3.055 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	4.237GluAla: 4.237 ± 0.075	0.314GluCys: 0.314 ± 0.018	3.798GluAsp: 3.798 ± 0.06	4.486GluGlu: 4.486 ± 0.079	3.095GluPhe: 3.095 ± 0.053	3.6GluGly: 3.6 ± 0.054	1.096GluHis: 1.096 ± 0.034	5.491GluIle: 5.491 ± 0.076	5.665GluLys: 5.665 ± 0.088	5.969GluLeu: 5.969 ± 0.081	1.364GluMet: 1.364 ± 0.038	5.075GluAsn: 5.075 ± 0.069	1.559GluPro: 1.559 ± 0.036	2.078GluGln: 2.078 ± 0.045	2.205GluArg: 2.205 ± 0.049	3.662GluSer: 3.662 ± 0.056	4.002GluThr: 4.002 ± 0.053	4.042GluVal: 4.042 ± 0.067	0.623GluTrp: 0.623 ± 0.027	2.459GluTyr: 2.459 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	2.782PheAla: 2.782 ± 0.053	0.431PheCys: 0.431 ± 0.019	3.269PheAsp: 3.269 ± 0.058	3.427PheGlu: 3.427 ± 0.055	2.73PhePhe: 2.73 ± 0.06	3.665PheGly: 3.665 ± 0.057	0.807PheHis: 0.807 ± 0.024	4.275PheIle: 4.275 ± 0.067	4.277PheLys: 4.277 ± 0.061	4.822PheLeu: 4.822 ± 0.074	1.071PheMet: 1.071 ± 0.028	3.878PheAsn: 3.878 ± 0.06	1.638PhePro: 1.638 ± 0.036	1.456PheGln: 1.456 ± 0.032	1.451PheArg: 1.451 ± 0.034	4.142PheSer: 4.142 ± 0.064	3.107PheThr: 3.107 ± 0.057	2.939PheVal: 2.939 ± 0.048	0.567PheTrp: 0.567 ± 0.022	2.272PheTyr: 2.272 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	3.821GlyAla: 3.821 ± 0.07	0.602GlyCys: 0.602 ± 0.038	3.456GlyAsp: 3.456 ± 0.057	3.629GlyGlu: 3.629 ± 0.058	3.683GlyPhe: 3.683 ± 0.061	4.469GlyGly: 4.469 ± 0.097	1.105GlyHis: 1.105 ± 0.033	5.458GlyIle: 5.458 ± 0.075	4.653GlyLys: 4.653 ± 0.061	5.687GlyLeu: 5.687 ± 0.083	1.428GlyMet: 1.428 ± 0.041	3.881GlyAsn: 3.881 ± 0.067	1.21GlyPro: 1.21 ± 0.037	1.689GlyGln: 1.689 ± 0.039	1.914GlyArg: 1.914 ± 0.042	3.966GlySer: 3.966 ± 0.082	3.828GlyThr: 3.828 ± 0.092	4.258GlyVal: 4.258 ± 0.063	0.764GlyTrp: 0.764 ± 0.027	2.854GlyTyr: 2.854 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	0.901HisAla: 0.901 ± 0.03	0.171HisCys: 0.171 ± 0.012	0.884HisAsp: 0.884 ± 0.028	0.915HisGlu: 0.915 ± 0.026	1.101HisPhe: 1.101 ± 0.028	0.979HisGly: 0.979 ± 0.029	0.422HisHis: 0.422 ± 0.019	1.493HisIle: 1.493 ± 0.041	1.259HisLys: 1.259 ± 0.034	1.704HisLeu: 1.704 ± 0.04	0.303HisMet: 0.303 ± 0.015	1.042HisAsn: 1.042 ± 0.027	0.832HisPro: 0.832 ± 0.03	0.637HisGln: 0.637 ± 0.024	0.54HisArg: 0.54 ± 0.022	0.993HisSer: 0.993 ± 0.033	0.89HisThr: 0.89 ± 0.025	0.871HisVal: 0.871 ± 0.027	0.219HisTrp: 0.219 ± 0.013	0.8HisTyr: 0.8 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.306IleAla: 5.306 ± 0.08	0.649IleCys: 0.649 ± 0.029	5.322IleAsp: 5.322 ± 0.075	5.941IleGlu: 5.941 ± 0.078	3.738IlePhe: 3.738 ± 0.066	5.269IleGly: 5.269 ± 0.076	1.373IleHis: 1.373 ± 0.041	7.181IleIle: 7.181 ± 0.088	6.767IleLys: 6.767 ± 0.08	7.281IleLeu: 7.281 ± 0.093	1.512IleMet: 1.512 ± 0.038	5.769IleAsn: 5.769 ± 0.081	3.334IlePro: 3.334 ± 0.051	2.506IleGln: 2.506 ± 0.045	2.408IleArg: 2.408 ± 0.039	6.224IleSer: 6.224 ± 0.078	5.229IleThr: 5.229 ± 0.084	4.846IleVal: 4.846 ± 0.059	0.743IleTrp: 0.743 ± 0.027	3.098IleTyr: 3.098 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	4.86LysAla: 4.86 ± 0.069	0.37LysCys: 0.37 ± 0.018	4.736LysAsp: 4.736 ± 0.061	6.2LysGlu: 6.2 ± 0.101	3.088LysPhe: 3.088 ± 0.055	4.507LysGly: 4.507 ± 0.066	1.556LysHis: 1.556 ± 0.033	6.48LysIle: 6.48 ± 0.087	7.036LysLys: 7.036 ± 0.096	7.12LysLeu: 7.12 ± 0.092	1.962LysMet: 1.962 ± 0.047	5.951LysAsn: 5.951 ± 0.083	2.544LysPro: 2.544 ± 0.056	2.971LysGln: 2.971 ± 0.057	2.809LysArg: 2.809 ± 0.057	4.87LysSer: 4.87 ± 0.068	5.154LysThr: 5.154 ± 0.074	4.597LysVal: 4.597 ± 0.077	0.793LysTrp: 0.793 ± 0.025	3.204LysTyr: 3.204 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	5.241LeuAla: 5.241 ± 0.074	0.666LeuCys: 0.666 ± 0.022	5.176LeuAsp: 5.176 ± 0.07	6.06LeuGlu: 6.06 ± 0.083	4.995LeuPhe: 4.995 ± 0.072	5.597LeuGly: 5.597 ± 0.082	1.448LeuHis: 1.448 ± 0.034	7.531LeuIle: 7.531 ± 0.093	8.363LeuLys: 8.363 ± 0.102	8.428LeuLeu: 8.428 ± 0.11	1.936LeuMet: 1.936 ± 0.042	6.52LeuAsn: 6.52 ± 0.079	3.376LeuPro: 3.376 ± 0.06	2.96LeuGln: 2.96 ± 0.056	2.835LeuArg: 2.835 ± 0.047	6.668LeuSer: 6.668 ± 0.087	5.111LeuThr: 5.111 ± 0.085	5.245LeuVal: 5.245 ± 0.079	0.787LeuTrp: 0.787 ± 0.031	3.221LeuTyr: 3.221 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	1.472MetAla: 1.472 ± 0.037	0.132MetCys: 0.132 ± 0.011	1.077MetAsp: 1.077 ± 0.03	1.206MetGlu: 1.206 ± 0.032	0.887MetPhe: 0.887 ± 0.026	1.222MetGly: 1.222 ± 0.032	0.399MetHis: 0.399 ± 0.018	1.454MetIle: 1.454 ± 0.041	2.035MetLys: 2.035 ± 0.045	1.894MetLeu: 1.894 ± 0.044	0.529MetMet: 0.529 ± 0.022	1.299MetAsn: 1.299 ± 0.027	0.812MetPro: 0.812 ± 0.028	0.766MetGln: 0.766 ± 0.023	0.757MetArg: 0.757 ± 0.025	1.429MetSer: 1.429 ± 0.034	1.114MetThr: 1.114 ± 0.029	1.302MetVal: 1.302 ± 0.037	0.174MetTrp: 0.174 ± 0.013	0.721MetTyr: 0.721 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.821AsnAla: 3.821 ± 0.069	0.554AsnCys: 0.554 ± 0.025	3.917AsnAsp: 3.917 ± 0.064	4.32AsnGlu: 4.32 ± 0.063	3.25AsnPhe: 3.25 ± 0.056	4.276AsnGly: 4.276 ± 0.084	1.18AsnHis: 1.18 ± 0.035	5.963AsnIle: 5.963 ± 0.077	5.347AsnLys: 5.347 ± 0.076	6.047AsnLeu: 6.047 ± 0.075	1.385AsnMet: 1.385 ± 0.033	4.97AsnAsn: 4.97 ± 0.092	2.878AsnPro: 2.878 ± 0.053	2.35AsnGln: 2.35 ± 0.048	2.152AsnArg: 2.152 ± 0.048	4.463AsnSer: 4.463 ± 0.079	4.3AsnThr: 4.3 ± 0.089	3.746AsnVal: 3.746 ± 0.062	0.84AsnTrp: 0.84 ± 0.023	3.249AsnTyr: 3.249 ± 0.055	0.0AsnXaa: 0.0 ± 0.0
Pro	1.555ProAla: 1.555 ± 0.038	0.194ProCys: 0.194 ± 0.011	1.982ProAsp: 1.982 ± 0.043	2.661ProGlu: 2.661 ± 0.053	1.895ProPhe: 1.895 ± 0.039	1.718ProGly: 1.718 ± 0.045	0.555ProHis: 0.555 ± 0.021	2.872ProIle: 2.872 ± 0.048	2.549ProLys: 2.549 ± 0.055	2.853ProLeu: 2.853 ± 0.05	0.673ProMet: 0.673 ± 0.026	2.472ProAsn: 2.472 ± 0.049	0.759ProPro: 0.759 ± 0.028	1.024ProGln: 1.024 ± 0.026	0.851ProArg: 0.851 ± 0.024	2.119ProSer: 2.119 ± 0.044	1.934ProThr: 1.934 ± 0.06	2.038ProVal: 2.038 ± 0.042	0.367ProTrp: 0.367 ± 0.02	1.358ProTyr: 1.358 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	1.758GlnAla: 1.758 ± 0.04	0.186GlnCys: 0.186 ± 0.015	1.656GlnAsp: 1.656 ± 0.039	2.0GlnGlu: 2.0 ± 0.044	1.684GlnPhe: 1.684 ± 0.037	1.731GlnGly: 1.731 ± 0.039	0.544GlnHis: 0.544 ± 0.02	2.643GlnIle: 2.643 ± 0.047	2.582GlnLys: 2.582 ± 0.048	3.193GlnLeu: 3.193 ± 0.059	0.706GlnMet: 0.706 ± 0.023	2.299GlnAsn: 2.299 ± 0.043	0.977GlnPro: 0.977 ± 0.028	1.209GlnGln: 1.209 ± 0.038	1.029GlnArg: 1.029 ± 0.031	1.858GlnSer: 1.858 ± 0.041	1.83GlnThr: 1.83 ± 0.036	1.836GlnVal: 1.836 ± 0.037	0.321GlnTrp: 0.321 ± 0.015	1.342GlnTyr: 1.342 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	1.841ArgAla: 1.841 ± 0.046	0.19ArgCys: 0.19 ± 0.014	1.675ArgAsp: 1.675 ± 0.039	1.896ArgGlu: 1.896 ± 0.046	1.805ArgPhe: 1.805 ± 0.035	1.816ArgGly: 1.816 ± 0.041	0.547ArgHis: 0.547 ± 0.021	2.663ArgIle: 2.663 ± 0.049	2.491ArgLys: 2.491 ± 0.062	2.943ArgLeu: 2.943 ± 0.046	0.716ArgMet: 0.716 ± 0.022	1.98ArgAsn: 1.98 ± 0.039	0.96ArgPro: 0.96 ± 0.03	0.959ArgGln: 0.959 ± 0.028	1.095ArgArg: 1.095 ± 0.033	1.715ArgSer: 1.715 ± 0.039	1.704ArgThr: 1.704 ± 0.041	1.892ArgVal: 1.892 ± 0.043	0.33ArgTrp: 0.33 ± 0.016	1.387ArgTyr: 1.387 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.565SerAla: 3.565 ± 0.063	0.666SerCys: 0.666 ± 0.023	3.591SerAsp: 3.591 ± 0.061	4.098SerGlu: 4.098 ± 0.055	3.919SerPhe: 3.919 ± 0.062	4.654SerGly: 4.654 ± 0.086	1.111SerHis: 1.111 ± 0.032	6.0SerIle: 6.0 ± 0.077	5.559SerLys: 5.559 ± 0.074	6.152SerLeu: 6.152 ± 0.08	1.216SerMet: 1.216 ± 0.033	4.666SerAsn: 4.666 ± 0.078	2.041SerPro: 2.041 ± 0.052	2.193SerGln: 2.193 ± 0.04	1.96SerArg: 1.96 ± 0.041	4.54SerSer: 4.54 ± 0.085	3.68SerThr: 3.68 ± 0.073	3.897SerVal: 3.897 ± 0.058	0.737SerTrp: 0.737 ± 0.029	2.77SerTyr: 2.77 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	3.487ThrAla: 3.487 ± 0.085	0.381ThrCys: 0.381 ± 0.024	3.266ThrAsp: 3.266 ± 0.066	3.363ThrGlu: 3.363 ± 0.057	3.177ThrPhe: 3.177 ± 0.056	3.953ThrGly: 3.953 ± 0.088	0.99ThrHis: 0.99 ± 0.027	5.367ThrIle: 5.367 ± 0.083	4.223ThrLys: 4.223 ± 0.066	5.51ThrLeu: 5.51 ± 0.075	0.939ThrMet: 0.939 ± 0.027	3.89ThrAsn: 3.89 ± 0.081	2.351ThrPro: 2.351 ± 0.058	1.816ThrGln: 1.816 ± 0.038	1.509ThrArg: 1.509 ± 0.037	4.148ThrSer: 4.148 ± 0.072	3.666ThrThr: 3.666 ± 0.088	3.566ThrVal: 3.566 ± 0.078	0.604ThrTrp: 0.604 ± 0.024	2.623ThrTyr: 2.623 ± 0.065	0.0ThrXaa: 0.0 ± 0.0
Val	3.593ValAla: 3.593 ± 0.065	0.499ValCys: 0.499 ± 0.022	3.452ValAsp: 3.452 ± 0.055	3.766ValGlu: 3.766 ± 0.055	3.47ValPhe: 3.47 ± 0.053	3.59ValGly: 3.59 ± 0.059	0.859ValHis: 0.859 ± 0.027	4.883ValIle: 4.883 ± 0.069	4.538ValLys: 4.538 ± 0.071	5.823ValLeu: 5.823 ± 0.081	1.194ValMet: 1.194 ± 0.032	3.807ValAsn: 3.807 ± 0.052	1.945ValPro: 1.945 ± 0.04	1.486ValGln: 1.486 ± 0.037	1.783ValArg: 1.783 ± 0.037	4.509ValSer: 4.509 ± 0.065	3.514ValThr: 3.514 ± 0.071	3.921ValVal: 3.921 ± 0.071	0.583ValTrp: 0.583 ± 0.026	2.385ValTyr: 2.385 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.574TrpAla: 0.574 ± 0.021	0.103TrpCys: 0.103 ± 0.01	0.605TrpAsp: 0.605 ± 0.024	0.691TrpGlu: 0.691 ± 0.021	0.58TrpPhe: 0.58 ± 0.022	0.638TrpGly: 0.638 ± 0.024	0.225TrpHis: 0.225 ± 0.015	0.773TrpIle: 0.773 ± 0.025	0.813TrpLys: 0.813 ± 0.026	1.02TrpLeu: 1.02 ± 0.032	0.278TrpMet: 0.278 ± 0.018	0.779TrpAsn: 0.779 ± 0.029	0.227TrpPro: 0.227 ± 0.016	0.381TrpGln: 0.381 ± 0.019	0.385TrpArg: 0.385 ± 0.017	0.684TrpSer: 0.684 ± 0.029	0.555TrpThr: 0.555 ± 0.021	0.617TrpVal: 0.617 ± 0.02	0.168TrpTrp: 0.168 ± 0.012	0.45TrpTyr: 0.45 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.379TyrAla: 2.379 ± 0.047	0.327TyrCys: 0.327 ± 0.015	2.328TyrAsp: 2.328 ± 0.052	2.297TyrGlu: 2.297 ± 0.047	2.473TyrPhe: 2.473 ± 0.044	2.629TyrGly: 2.629 ± 0.046	0.799TyrHis: 0.799 ± 0.029	3.019TyrIle: 3.019 ± 0.054	3.433TyrLys: 3.433 ± 0.054	3.907TyrLeu: 3.907 ± 0.048	0.786TyrMet: 0.786 ± 0.023	3.156TyrAsn: 3.156 ± 0.054	1.47TyrPro: 1.47 ± 0.037	1.491TyrGln: 1.491 ± 0.035	1.441TyrArg: 1.441 ± 0.039	2.852TyrSer: 2.852 ± 0.058	2.523TyrThr: 2.523 ± 0.063	2.152TyrVal: 2.152 ± 0.041	0.514TyrTrp: 0.514 ± 0.023	1.94TyrTyr: 1.94 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3670 proteins (1276762 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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