Amino acid dipepetide frequency for Apis mellifera associated microvirus 29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.881AlaAla: 6.881 ± 2.91
0.765AlaCys: 0.765 ± 0.808
4.587AlaAsp: 4.587 ± 2.087
3.058AlaGlu: 3.058 ± 1.1
3.058AlaPhe: 3.058 ± 1.459
5.352AlaGly: 5.352 ± 2.326
1.529AlaHis: 1.529 ± 0.696
5.352AlaIle: 5.352 ± 1.371
5.352AlaLys: 5.352 ± 2.815
7.645AlaLeu: 7.645 ± 2.402
1.529AlaMet: 1.529 ± 0.696
6.116AlaAsn: 6.116 ± 1.939
3.823AlaPro: 3.823 ± 1.31
3.823AlaGln: 3.823 ± 1.593
6.116AlaArg: 6.116 ± 1.73
5.352AlaSer: 5.352 ± 2.275
5.352AlaThr: 5.352 ± 1.827
3.058AlaVal: 3.058 ± 1.584
0.0AlaTrp: 0.0 ± 0.0
4.587AlaTyr: 4.587 ± 1.269
0.0AlaXaa: 0.0 ± 0.0
Cys
0.765CysAla: 0.765 ± 0.527
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.765CysPhe: 0.765 ± 0.808
0.765CysGly: 0.765 ± 0.808
0.765CysHis: 0.765 ± 0.808
0.765CysIle: 0.765 ± 0.808
0.0CysLys: 0.0 ± 0.0
1.529CysLeu: 1.529 ± 1.047
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.765CysPro: 0.765 ± 0.527
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.765CysSer: 0.765 ± 0.806
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.529CysTyr: 1.529 ± 0.648
0.0CysXaa: 0.0 ± 0.0
Asp
6.116AspAla: 6.116 ± 1.117
1.529AspCys: 1.529 ± 0.845
1.529AspAsp: 1.529 ± 1.054
6.116AspGlu: 6.116 ± 3.374
2.294AspPhe: 2.294 ± 1.582
2.294AspGly: 2.294 ± 0.617
0.765AspHis: 0.765 ± 0.527
1.529AspIle: 1.529 ± 1.083
0.765AspLys: 0.765 ± 0.808
5.352AspLeu: 5.352 ± 1.16
0.0AspMet: 0.0 ± 0.0
2.294AspAsn: 2.294 ± 1.155
1.529AspPro: 1.529 ± 1.047
2.294AspGln: 2.294 ± 1.172
1.529AspArg: 1.529 ± 1.054
3.058AspSer: 3.058 ± 1.486
6.881AspThr: 6.881 ± 2.655
0.765AspVal: 0.765 ± 0.527
0.0AspTrp: 0.0 ± 0.0
3.823AspTyr: 3.823 ± 1.572
0.0AspXaa: 0.0 ± 0.0
Glu
5.352GluAla: 5.352 ± 2.625
0.765GluCys: 0.765 ± 0.808
0.765GluAsp: 0.765 ± 0.808
1.529GluGlu: 1.529 ± 1.047
2.294GluPhe: 2.294 ± 1.367
1.529GluGly: 1.529 ± 0.845
1.529GluHis: 1.529 ± 1.054
4.587GluIle: 4.587 ± 1.732
5.352GluLys: 5.352 ± 2.104
3.823GluLeu: 3.823 ± 2.521
0.0GluMet: 0.0 ± 0.0
6.881GluAsn: 6.881 ± 0.724
1.529GluPro: 1.529 ± 0.845
3.058GluGln: 3.058 ± 0.556
2.294GluArg: 2.294 ± 0.617
0.765GluSer: 0.765 ± 0.806
4.587GluThr: 4.587 ± 2.447
3.823GluVal: 3.823 ± 1.037
1.529GluTrp: 1.529 ± 0.648
4.587GluTyr: 4.587 ± 1.906
0.0GluXaa: 0.0 ± 0.0
Phe
2.294PheAla: 2.294 ± 1.582
0.0PheCys: 0.0 ± 0.0
3.823PheAsp: 3.823 ± 2.129
1.529PheGlu: 1.529 ± 1.436
1.529PhePhe: 1.529 ± 1.054
5.352PheGly: 5.352 ± 1.226
0.0PheHis: 0.0 ± 0.0
3.058PheIle: 3.058 ± 0.87
0.765PheLys: 0.765 ± 0.806
3.823PheLeu: 3.823 ± 1.22
2.294PheMet: 2.294 ± 0.823
4.587PheAsn: 4.587 ± 0.949
1.529PhePro: 1.529 ± 0.648
2.294PheGln: 2.294 ± 0.617
1.529PheArg: 1.529 ± 0.648
2.294PheSer: 2.294 ± 1.582
5.352PheThr: 5.352 ± 1.225
1.529PheVal: 1.529 ± 1.054
0.765PheTrp: 0.765 ± 0.527
3.058PheTyr: 3.058 ± 1.202
0.0PheXaa: 0.0 ± 0.0
Gly
5.352GlyAla: 5.352 ± 3.487
0.0GlyCys: 0.0 ± 0.0
1.529GlyAsp: 1.529 ± 1.054
4.587GlyGlu: 4.587 ± 1.095
3.823GlyPhe: 3.823 ± 1.748
7.645GlyGly: 7.645 ± 2.273
0.765GlyHis: 0.765 ± 0.808
3.823GlyIle: 3.823 ± 0.498
4.587GlyLys: 4.587 ± 2.734
6.881GlyLeu: 6.881 ± 1.533
0.765GlyMet: 0.765 ± 0.527
5.352GlyAsn: 5.352 ± 0.932
0.765GlyPro: 0.765 ± 0.527
0.0GlyGln: 0.0 ± 0.0
1.529GlyArg: 1.529 ± 0.648
8.41GlySer: 8.41 ± 2.663
5.352GlyThr: 5.352 ± 1.852
2.294GlyVal: 2.294 ± 1.565
0.0GlyTrp: 0.0 ± 0.0
2.294GlyTyr: 2.294 ± 0.861
0.0GlyXaa: 0.0 ± 0.0
His
1.529HisAla: 1.529 ± 1.617
0.0HisCys: 0.0 ± 0.0
3.058HisAsp: 3.058 ± 2.087
4.587HisGlu: 4.587 ± 2.881
3.823HisPhe: 3.823 ± 2.636
2.294HisGly: 2.294 ± 0.961
1.529HisHis: 1.529 ± 1.617
0.765HisIle: 0.765 ± 0.806
0.0HisLys: 0.0 ± 0.0
1.529HisLeu: 1.529 ± 1.054
0.765HisMet: 0.765 ± 1.177
1.529HisAsn: 1.529 ± 0.696
0.0HisPro: 0.0 ± 0.0
1.529HisGln: 1.529 ± 1.436
0.765HisArg: 0.765 ± 0.808
1.529HisSer: 1.529 ± 1.617
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.765HisTyr: 0.765 ± 0.808
0.0HisXaa: 0.0 ± 0.0
Ile
3.823IleAla: 3.823 ± 1.981
0.0IleCys: 0.0 ± 0.0
6.116IleAsp: 6.116 ± 1.468
0.765IleGlu: 0.765 ± 0.527
5.352IlePhe: 5.352 ± 1.694
3.823IleGly: 3.823 ± 1.981
0.765IleHis: 0.765 ± 1.14
4.587IleIle: 4.587 ± 1.281
2.294IleLys: 2.294 ± 1.367
4.587IleLeu: 4.587 ± 1.327
1.529IleMet: 1.529 ± 0.845
4.587IleAsn: 4.587 ± 0.72
3.058IlePro: 3.058 ± 1.689
3.823IleGln: 3.823 ± 1.415
2.294IleArg: 2.294 ± 0.918
0.765IleSer: 0.765 ± 0.527
3.058IleThr: 3.058 ± 0.87
3.823IleVal: 3.823 ± 1.74
1.529IleTrp: 1.529 ± 0.696
0.765IleTyr: 0.765 ± 0.527
0.0IleXaa: 0.0 ± 0.0
Lys
3.058LysAla: 3.058 ± 2.155
1.529LysCys: 1.529 ± 0.648
4.587LysAsp: 4.587 ± 1.095
1.529LysGlu: 1.529 ± 0.648
2.294LysPhe: 2.294 ± 0.806
4.587LysGly: 4.587 ± 1.095
1.529LysHis: 1.529 ± 1.004
3.823LysIle: 3.823 ± 1.31
5.352LysLys: 5.352 ± 3.25
6.881LysLeu: 6.881 ± 3.66
1.529LysMet: 1.529 ± 0.944
3.058LysAsn: 3.058 ± 2.008
3.058LysPro: 3.058 ± 0.87
3.058LysGln: 3.058 ± 1.688
4.587LysArg: 4.587 ± 2.813
3.058LysSer: 3.058 ± 1.034
5.352LysThr: 5.352 ± 1.029
0.765LysVal: 0.765 ± 0.774
0.0LysTrp: 0.0 ± 0.0
2.294LysTyr: 2.294 ± 1.043
0.0LysXaa: 0.0 ± 0.0
Leu
5.352LeuAla: 5.352 ± 2.286
0.765LeuCys: 0.765 ± 0.806
3.823LeuAsp: 3.823 ± 1.037
3.823LeuGlu: 3.823 ± 2.691
3.058LeuPhe: 3.058 ± 1.034
3.058LeuGly: 3.058 ± 1.334
2.294LeuHis: 2.294 ± 0.961
4.587LeuIle: 4.587 ± 2.112
8.41LeuLys: 8.41 ± 3.057
6.116LeuLeu: 6.116 ± 1.558
0.765LeuMet: 0.765 ± 0.806
6.881LeuAsn: 6.881 ± 2.317
9.174LeuPro: 9.174 ± 1.154
3.823LeuGln: 3.823 ± 1.22
6.881LeuArg: 6.881 ± 3.183
6.116LeuSer: 6.116 ± 2.659
3.058LeuThr: 3.058 ± 1.296
4.587LeuVal: 4.587 ± 2.066
1.529LeuTrp: 1.529 ± 0.648
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.294MetAla: 2.294 ± 2.322
0.765MetCys: 0.765 ± 0.808
2.294MetAsp: 2.294 ± 0.806
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.529MetGly: 1.529 ± 1.054
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
4.587MetLys: 4.587 ± 2.574
0.765MetLeu: 0.765 ± 0.774
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.529MetPro: 1.529 ± 1.054
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.529MetSer: 1.529 ± 1.548
0.0MetThr: 0.0 ± 0.0
1.529MetVal: 1.529 ± 0.648
0.765MetTrp: 0.765 ± 0.527
0.765MetTyr: 0.765 ± 0.527
0.0MetXaa: 0.0 ± 0.0
Asn
5.352AsnAla: 5.352 ± 2.961
0.765AsnCys: 0.765 ± 0.808
0.765AsnAsp: 0.765 ± 0.806
3.823AsnGlu: 3.823 ± 1.974
2.294AsnPhe: 2.294 ± 1.043
2.294AsnGly: 2.294 ± 0.617
1.529AsnHis: 1.529 ± 1.612
5.352AsnIle: 5.352 ± 2.051
3.058AsnLys: 3.058 ± 1.791
5.352AsnLeu: 5.352 ± 2.326
0.765AsnMet: 0.765 ± 0.751
3.823AsnAsn: 3.823 ± 1.585
5.352AsnPro: 5.352 ± 1.347
4.587AsnGln: 4.587 ± 0.968
3.823AsnArg: 3.823 ± 1.22
6.116AsnSer: 6.116 ± 1.834
5.352AsnThr: 5.352 ± 1.681
1.529AsnVal: 1.529 ± 1.054
0.765AsnTrp: 0.765 ± 0.527
3.058AsnTyr: 3.058 ± 3.234
0.0AsnXaa: 0.0 ± 0.0
Pro
3.058ProAla: 3.058 ± 0.87
0.765ProCys: 0.765 ± 0.808
3.058ProAsp: 3.058 ± 1.296
2.294ProGlu: 2.294 ± 0.617
1.529ProPhe: 1.529 ± 1.129
5.352ProGly: 5.352 ± 1.16
2.294ProHis: 2.294 ± 1.043
3.823ProIle: 3.823 ± 0.891
0.765ProLys: 0.765 ± 0.774
4.587ProLeu: 4.587 ± 1.778
0.765ProMet: 0.765 ± 0.527
0.765ProAsn: 0.765 ± 0.808
2.294ProPro: 2.294 ± 1.343
6.881ProGln: 6.881 ± 3.614
2.294ProArg: 2.294 ± 1.367
5.352ProSer: 5.352 ± 2.218
4.587ProThr: 4.587 ± 2.555
1.529ProVal: 1.529 ± 1.054
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.587GlnAla: 4.587 ± 1.774
0.0GlnCys: 0.0 ± 0.0
0.765GlnAsp: 0.765 ± 0.774
6.881GlnGlu: 6.881 ± 1.407
2.294GlnPhe: 2.294 ± 1.662
3.058GlnGly: 3.058 ± 1.386
0.0GlnHis: 0.0 ± 0.0
3.058GlnIle: 3.058 ± 1.386
3.058GlnLys: 3.058 ± 1.296
3.058GlnLeu: 3.058 ± 0.87
1.529GlnMet: 1.529 ± 1.548
6.116GlnAsn: 6.116 ± 2.344
0.765GlnPro: 0.765 ± 0.806
3.823GlnGln: 3.823 ± 1.271
4.587GlnArg: 4.587 ± 2.363
1.529GlnSer: 1.529 ± 1.047
1.529GlnThr: 1.529 ± 0.648
2.294GlnVal: 2.294 ± 0.918
0.0GlnTrp: 0.0 ± 0.0
1.529GlnTyr: 1.529 ± 1.612
0.0GlnXaa: 0.0 ± 0.0
Arg
3.058ArgAla: 3.058 ± 1.052
0.0ArgCys: 0.0 ± 0.0
1.529ArgAsp: 1.529 ± 0.648
2.294ArgGlu: 2.294 ± 1.374
2.294ArgPhe: 2.294 ± 1.367
2.294ArgGly: 2.294 ± 0.961
2.294ArgHis: 2.294 ± 1.65
1.529ArgIle: 1.529 ± 1.054
4.587ArgLys: 4.587 ± 1.974
3.823ArgLeu: 3.823 ± 1.43
2.294ArgMet: 2.294 ± 0.961
0.765ArgAsn: 0.765 ± 0.774
3.823ArgPro: 3.823 ± 1.981
2.294ArgGln: 2.294 ± 0.806
1.529ArgArg: 1.529 ± 1.612
6.116ArgSer: 6.116 ± 2.271
2.294ArgThr: 2.294 ± 1.367
0.765ArgVal: 0.765 ± 0.806
0.0ArgTrp: 0.0 ± 0.0
3.058ArgTyr: 3.058 ± 1.273
0.0ArgXaa: 0.0 ± 0.0
Ser
7.645SerAla: 7.645 ± 3.016
0.0SerCys: 0.0 ± 0.0
3.823SerAsp: 3.823 ± 1.237
4.587SerGlu: 4.587 ± 1.951
4.587SerPhe: 4.587 ± 1.588
3.058SerGly: 3.058 ± 1.034
3.823SerHis: 3.823 ± 1.43
1.529SerIle: 1.529 ± 0.648
2.294SerLys: 2.294 ± 1.482
7.645SerLeu: 7.645 ± 0.995
0.765SerMet: 0.765 ± 0.808
5.352SerAsn: 5.352 ± 1.347
3.058SerPro: 3.058 ± 1.241
3.058SerGln: 3.058 ± 1.334
1.529SerArg: 1.529 ± 0.648
3.823SerSer: 3.823 ± 2.024
8.41SerThr: 8.41 ± 3.196
2.294SerVal: 2.294 ± 0.961
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
9.939ThrAla: 9.939 ± 1.971
0.0ThrCys: 0.0 ± 0.0
3.823ThrAsp: 3.823 ± 1.22
3.823ThrGlu: 3.823 ± 1.361
3.058ThrPhe: 3.058 ± 1.273
7.645ThrGly: 7.645 ± 0.971
2.294ThrHis: 2.294 ± 1.043
3.058ThrIle: 3.058 ± 1.689
3.823ThrLys: 3.823 ± 1.221
6.116ThrLeu: 6.116 ± 1.151
0.0ThrMet: 0.0 ± 0.0
3.823ThrAsn: 3.823 ± 1.118
5.352ThrPro: 5.352 ± 1.242
1.529ThrGln: 1.529 ± 1.083
3.058ThrArg: 3.058 ± 1.034
3.823ThrSer: 3.823 ± 1.748
5.352ThrThr: 5.352 ± 1.684
6.881ThrVal: 6.881 ± 1.952
0.0ThrTrp: 0.0 ± 0.0
2.294ThrTyr: 2.294 ± 0.861
0.0ThrXaa: 0.0 ± 0.0
Val
2.294ValAla: 2.294 ± 0.961
0.0ValCys: 0.0 ± 0.0
3.058ValAsp: 3.058 ± 1.473
1.529ValGlu: 1.529 ± 1.129
1.529ValPhe: 1.529 ± 1.054
0.765ValGly: 0.765 ± 0.527
1.529ValHis: 1.529 ± 1.275
3.058ValIle: 3.058 ± 1.386
3.823ValLys: 3.823 ± 1.221
1.529ValLeu: 1.529 ± 1.047
0.765ValMet: 0.765 ± 0.527
2.294ValAsn: 2.294 ± 0.918
2.294ValPro: 2.294 ± 1.582
0.765ValGln: 0.765 ± 0.774
0.765ValArg: 0.765 ± 0.527
3.823ValSer: 3.823 ± 1.748
6.881ValThr: 6.881 ± 1.207
0.0ValVal: 0.0 ± 0.0
0.765ValTrp: 0.765 ± 0.527
0.765ValTyr: 0.765 ± 0.808
0.0ValXaa: 0.0 ± 0.0
Trp
0.765TrpAla: 0.765 ± 0.808
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.765TrpGlu: 0.765 ± 0.527
0.0TrpPhe: 0.0 ± 0.0
0.765TrpGly: 0.765 ± 0.808
0.765TrpHis: 0.765 ± 0.527
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.765TrpAsn: 0.765 ± 0.527
0.765TrpPro: 0.765 ± 0.527
0.765TrpGln: 0.765 ± 0.527
0.0TrpArg: 0.0 ± 0.0
1.529TrpSer: 1.529 ± 0.696
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.765TrpTyr: 0.765 ± 0.527
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.823TyrAla: 3.823 ± 1.748
0.765TyrCys: 0.765 ± 0.527
1.529TyrAsp: 1.529 ± 0.845
3.058TyrGlu: 3.058 ± 1.375
1.529TyrPhe: 1.529 ± 1.054
2.294TyrGly: 2.294 ± 1.172
0.765TyrHis: 0.765 ± 0.808
3.058TyrIle: 3.058 ± 2.489
3.058TyrLys: 3.058 ± 1.296
3.058TyrLeu: 3.058 ± 1.486
1.529TyrMet: 1.529 ± 1.275
0.765TyrAsn: 0.765 ± 0.808
1.529TyrPro: 1.529 ± 1.129
3.058TyrGln: 3.058 ± 1.584
1.529TyrArg: 1.529 ± 1.054
1.529TyrSer: 1.529 ± 1.617
2.294TyrThr: 2.294 ± 1.343
0.765TyrVal: 0.765 ± 0.527
0.0TyrTrp: 0.0 ± 0.0
0.765TyrTyr: 0.765 ± 0.808
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1309 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski