Amino acid dipepetide frequency for Beihai sea slater virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.801AlaAla: 3.801 ± 0.834
1.663AlaCys: 1.663 ± 0.65
3.564AlaAsp: 3.564 ± 0.442
3.564AlaGlu: 3.564 ± 0.68
2.376AlaPhe: 2.376 ± 0.476
2.851AlaGly: 2.851 ± 0.688
1.901AlaHis: 1.901 ± 0.617
5.702AlaIle: 5.702 ± 1.354
4.039AlaLys: 4.039 ± 1.079
6.652AlaLeu: 6.652 ± 1.135
1.901AlaMet: 1.901 ± 0.413
2.376AlaAsn: 2.376 ± 0.388
1.188AlaPro: 1.188 ± 0.558
1.426AlaGln: 1.426 ± 0.571
2.138AlaArg: 2.138 ± 0.416
4.277AlaSer: 4.277 ± 0.9
4.277AlaThr: 4.277 ± 1.134
2.851AlaVal: 2.851 ± 0.933
0.713AlaTrp: 0.713 ± 0.371
3.326AlaTyr: 3.326 ± 1.149
0.0AlaXaa: 0.0 ± 0.0
Cys
1.901CysAla: 1.901 ± 0.741
0.0CysCys: 0.0 ± 0.0
1.188CysAsp: 1.188 ± 0.327
1.663CysGlu: 1.663 ± 0.776
0.713CysPhe: 0.713 ± 0.246
0.475CysGly: 0.475 ± 0.248
0.95CysHis: 0.95 ± 0.541
0.95CysIle: 0.95 ± 0.403
1.663CysLys: 1.663 ± 0.623
1.426CysLeu: 1.426 ± 0.492
0.713CysMet: 0.713 ± 0.331
0.475CysAsn: 0.475 ± 0.248
0.95CysPro: 0.95 ± 0.364
0.475CysGln: 0.475 ± 0.487
2.138CysArg: 2.138 ± 0.76
2.138CysSer: 2.138 ± 1.201
0.95CysThr: 0.95 ± 0.393
1.426CysVal: 1.426 ± 0.617
0.0CysTrp: 0.0 ± 0.0
0.713CysTyr: 0.713 ± 0.246
0.0CysXaa: 0.0 ± 0.0
Asp
2.613AspAla: 2.613 ± 0.483
0.95AspCys: 0.95 ± 0.495
5.464AspAsp: 5.464 ± 0.722
5.227AspGlu: 5.227 ± 1.096
5.702AspPhe: 5.702 ± 1.138
3.089AspGly: 3.089 ± 0.851
1.901AspHis: 1.901 ± 0.526
4.514AspIle: 4.514 ± 1.203
3.326AspLys: 3.326 ± 1.259
7.128AspLeu: 7.128 ± 0.709
0.95AspMet: 0.95 ± 0.311
2.613AspAsn: 2.613 ± 0.542
3.564AspPro: 3.564 ± 0.707
1.663AspGln: 1.663 ± 0.481
1.901AspArg: 1.901 ± 0.372
4.989AspSer: 4.989 ± 0.463
3.564AspThr: 3.564 ± 1.168
3.326AspVal: 3.326 ± 1.051
1.426AspTrp: 1.426 ± 0.579
3.326AspTyr: 3.326 ± 0.497
0.0AspXaa: 0.0 ± 0.0
Glu
3.089GluAla: 3.089 ± 1.046
0.95GluCys: 0.95 ± 0.566
2.613GluAsp: 2.613 ± 0.893
1.901GluGlu: 1.901 ± 0.99
3.089GluPhe: 3.089 ± 1.043
2.613GluGly: 2.613 ± 0.61
2.138GluHis: 2.138 ± 0.641
3.564GluIle: 3.564 ± 0.528
6.652GluLys: 6.652 ± 1.441
7.128GluLeu: 7.128 ± 0.984
0.95GluMet: 0.95 ± 0.517
2.851GluAsn: 2.851 ± 0.795
1.901GluPro: 1.901 ± 0.898
1.188GluGln: 1.188 ± 0.458
4.039GluArg: 4.039 ± 1.242
4.277GluSer: 4.277 ± 1.412
3.801GluThr: 3.801 ± 0.779
4.039GluVal: 4.039 ± 1.074
0.475GluTrp: 0.475 ± 0.304
2.851GluTyr: 2.851 ± 0.705
0.0GluXaa: 0.0 ± 0.0
Phe
3.089PheAla: 3.089 ± 1.17
0.95PheCys: 0.95 ± 0.512
3.801PheAsp: 3.801 ± 0.433
3.326PheGlu: 3.326 ± 0.633
0.95PhePhe: 0.95 ± 0.311
3.326PheGly: 3.326 ± 1.039
1.426PheHis: 1.426 ± 0.384
3.326PheIle: 3.326 ± 1.361
4.514PheLys: 4.514 ± 0.98
3.564PheLeu: 3.564 ± 0.531
0.238PheMet: 0.238 ± 0.124
1.663PheAsn: 1.663 ± 0.3
2.376PhePro: 2.376 ± 0.461
0.95PheGln: 0.95 ± 0.796
1.426PheArg: 1.426 ± 0.517
1.901PheSer: 1.901 ± 0.428
3.089PheThr: 3.089 ± 1.092
4.277PheVal: 4.277 ± 0.709
0.475PheTrp: 0.475 ± 0.234
2.138PheTyr: 2.138 ± 0.498
0.0PheXaa: 0.0 ± 0.0
Gly
2.376GlyAla: 2.376 ± 1.079
0.475GlyCys: 0.475 ± 0.248
4.039GlyAsp: 4.039 ± 0.289
2.138GlyGlu: 2.138 ± 0.531
2.851GlyPhe: 2.851 ± 0.925
0.95GlyGly: 0.95 ± 0.53
1.663GlyHis: 1.663 ± 0.892
2.138GlyIle: 2.138 ± 0.416
3.326GlyLys: 3.326 ± 0.921
3.801GlyLeu: 3.801 ± 0.698
1.426GlyMet: 1.426 ± 0.323
3.564GlyAsn: 3.564 ± 0.561
1.901GlyPro: 1.901 ± 0.422
1.901GlyGln: 1.901 ± 0.735
1.901GlyArg: 1.901 ± 0.738
2.613GlySer: 2.613 ± 1.663
2.376GlyThr: 2.376 ± 0.848
2.613GlyVal: 2.613 ± 0.459
0.713GlyTrp: 0.713 ± 0.311
2.613GlyTyr: 2.613 ± 0.929
0.0GlyXaa: 0.0 ± 0.0
His
2.613HisAla: 2.613 ± 0.616
0.713HisCys: 0.713 ± 0.246
0.95HisAsp: 0.95 ± 0.557
1.901HisGlu: 1.901 ± 0.422
2.851HisPhe: 2.851 ± 0.499
2.138HisGly: 2.138 ± 0.657
0.713HisHis: 0.713 ± 0.361
0.95HisIle: 0.95 ± 0.362
0.713HisLys: 0.713 ± 0.504
2.851HisLeu: 2.851 ± 0.535
0.713HisMet: 0.713 ± 0.371
1.663HisAsn: 1.663 ± 0.867
0.95HisPro: 0.95 ± 0.362
0.238HisGln: 0.238 ± 0.283
1.663HisArg: 1.663 ± 0.448
0.95HisSer: 0.95 ± 0.691
2.138HisThr: 2.138 ± 0.601
2.613HisVal: 2.613 ± 0.722
0.0HisTrp: 0.0 ± 0.0
0.475HisTyr: 0.475 ± 0.487
0.0HisXaa: 0.0 ± 0.0
Ile
3.326IleAla: 3.326 ± 0.592
1.663IleCys: 1.663 ± 0.593
5.227IleAsp: 5.227 ± 1.103
3.089IleGlu: 3.089 ± 0.791
1.901IlePhe: 1.901 ± 0.87
4.514IleGly: 4.514 ± 1.108
2.138IleHis: 2.138 ± 0.386
4.752IleIle: 4.752 ± 1.665
3.326IleLys: 3.326 ± 0.943
6.177IleLeu: 6.177 ± 1.197
1.901IleMet: 1.901 ± 0.342
4.039IleAsn: 4.039 ± 0.92
2.376IlePro: 2.376 ± 0.858
2.613IleGln: 2.613 ± 0.757
0.95IleArg: 0.95 ± 0.362
3.564IleSer: 3.564 ± 0.661
4.989IleThr: 4.989 ± 0.859
3.801IleVal: 3.801 ± 1.01
0.713IleTrp: 0.713 ± 0.286
2.138IleTyr: 2.138 ± 1.25
0.0IleXaa: 0.0 ± 0.0
Lys
4.752LysAla: 4.752 ± 2.184
2.138LysCys: 2.138 ± 1.097
3.801LysAsp: 3.801 ± 0.708
5.227LysGlu: 5.227 ± 2.176
1.663LysPhe: 1.663 ± 0.624
1.426LysGly: 1.426 ± 0.4
1.901LysHis: 1.901 ± 0.428
4.277LysIle: 4.277 ± 1.145
4.277LysLys: 4.277 ± 1.405
5.227LysLeu: 5.227 ± 1.368
1.188LysMet: 1.188 ± 0.301
2.376LysAsn: 2.376 ± 0.967
4.989LysPro: 4.989 ± 1.489
3.564LysGln: 3.564 ± 0.924
2.376LysArg: 2.376 ± 0.508
4.039LysSer: 4.039 ± 0.93
4.989LysThr: 4.989 ± 1.142
6.89LysVal: 6.89 ± 2.111
0.713LysTrp: 0.713 ± 0.464
4.277LysTyr: 4.277 ± 0.783
0.0LysXaa: 0.0 ± 0.0
Leu
4.752LeuAla: 4.752 ± 1.044
2.613LeuCys: 2.613 ± 0.809
6.177LeuAsp: 6.177 ± 0.671
4.989LeuGlu: 4.989 ± 1.126
4.514LeuPhe: 4.514 ± 1.273
3.564LeuGly: 3.564 ± 1.404
2.851LeuHis: 2.851 ± 0.605
2.851LeuIle: 2.851 ± 0.674
6.652LeuLys: 6.652 ± 1.558
6.415LeuLeu: 6.415 ± 1.839
1.426LeuMet: 1.426 ± 0.539
6.415LeuAsn: 6.415 ± 1.978
2.851LeuPro: 2.851 ± 0.511
3.801LeuGln: 3.801 ± 1.026
5.464LeuArg: 5.464 ± 0.943
5.94LeuSer: 5.94 ± 0.72
4.514LeuThr: 4.514 ± 0.715
7.128LeuVal: 7.128 ± 1.564
0.713LeuTrp: 0.713 ± 0.435
2.613LeuTyr: 2.613 ± 0.946
0.0LeuXaa: 0.0 ± 0.0
Met
1.901MetAla: 1.901 ± 0.57
0.0MetCys: 0.0 ± 0.0
1.663MetAsp: 1.663 ± 0.3
1.188MetGlu: 1.188 ± 0.263
0.713MetPhe: 0.713 ± 0.61
0.475MetGly: 0.475 ± 0.477
0.475MetHis: 0.475 ± 0.234
0.95MetIle: 0.95 ± 0.364
1.188MetLys: 1.188 ± 0.619
2.376MetLeu: 2.376 ± 0.7
0.238MetMet: 0.238 ± 0.371
1.663MetAsn: 1.663 ± 0.623
0.713MetPro: 0.713 ± 0.405
0.238MetGln: 0.238 ± 0.124
1.426MetArg: 1.426 ± 0.991
0.713MetSer: 0.713 ± 0.286
1.901MetThr: 1.901 ± 0.974
2.138MetVal: 2.138 ± 0.894
0.0MetTrp: 0.0 ± 0.0
0.95MetTyr: 0.95 ± 0.311
0.0MetXaa: 0.0 ± 0.0
Asn
2.376AsnAla: 2.376 ± 0.772
2.138AsnCys: 2.138 ± 0.656
1.663AsnAsp: 1.663 ± 0.617
4.277AsnGlu: 4.277 ± 0.5
2.138AsnPhe: 2.138 ± 0.386
3.089AsnGly: 3.089 ± 0.783
1.188AsnHis: 1.188 ± 0.362
4.039AsnIle: 4.039 ± 0.847
4.039AsnLys: 4.039 ± 1.534
4.514AsnLeu: 4.514 ± 0.803
0.238AsnMet: 0.238 ± 0.124
1.188AsnAsn: 1.188 ± 0.378
1.663AsnPro: 1.663 ± 0.55
2.613AsnGln: 2.613 ± 0.561
1.426AsnArg: 1.426 ± 0.383
2.376AsnSer: 2.376 ± 0.604
2.851AsnThr: 2.851 ± 0.975
3.801AsnVal: 3.801 ± 1.068
0.238AsnTrp: 0.238 ± 0.353
1.663AsnTyr: 1.663 ± 0.579
0.0AsnXaa: 0.0 ± 0.0
Pro
1.663ProAla: 1.663 ± 0.3
0.475ProCys: 0.475 ± 0.318
4.989ProAsp: 4.989 ± 1.501
2.851ProGlu: 2.851 ± 0.472
2.376ProPhe: 2.376 ± 0.654
1.188ProGly: 1.188 ± 0.405
0.95ProHis: 0.95 ± 0.512
3.089ProIle: 3.089 ± 0.747
2.613ProLys: 2.613 ± 0.822
2.851ProLeu: 2.851 ± 0.71
1.426ProMet: 1.426 ± 0.3
1.188ProAsn: 1.188 ± 0.433
2.376ProPro: 2.376 ± 0.76
2.138ProGln: 2.138 ± 0.285
1.426ProArg: 1.426 ± 0.899
2.138ProSer: 2.138 ± 0.329
3.801ProThr: 3.801 ± 0.538
3.801ProVal: 3.801 ± 0.593
0.238ProTrp: 0.238 ± 0.335
1.188ProTyr: 1.188 ± 0.557
0.0ProXaa: 0.0 ± 0.0
Gln
0.95GlnAla: 0.95 ± 0.468
0.475GlnCys: 0.475 ± 0.248
1.426GlnAsp: 1.426 ± 0.365
3.089GlnGlu: 3.089 ± 0.957
1.188GlnPhe: 1.188 ± 1.125
1.663GlnGly: 1.663 ± 0.3
0.95GlnHis: 0.95 ± 0.495
2.613GlnIle: 2.613 ± 1.229
1.426GlnLys: 1.426 ± 0.527
3.564GlnLeu: 3.564 ± 0.561
1.188GlnMet: 1.188 ± 0.43
1.426GlnAsn: 1.426 ± 0.631
2.138GlnPro: 2.138 ± 0.795
2.851GlnGln: 2.851 ± 1.022
2.613GlnArg: 2.613 ± 1.017
2.376GlnSer: 2.376 ± 0.794
2.851GlnThr: 2.851 ± 1.003
1.188GlnVal: 1.188 ± 0.65
0.0GlnTrp: 0.0 ± 0.0
0.95GlnTyr: 0.95 ± 0.311
0.0GlnXaa: 0.0 ± 0.0
Arg
3.326ArgAla: 3.326 ± 0.817
0.475ArgCys: 0.475 ± 0.49
3.089ArgAsp: 3.089 ± 0.69
2.613ArgGlu: 2.613 ± 0.801
1.901ArgPhe: 1.901 ± 0.727
3.326ArgGly: 3.326 ± 1.189
1.426ArgHis: 1.426 ± 0.3
3.326ArgIle: 3.326 ± 0.747
2.851ArgLys: 2.851 ± 0.933
4.514ArgLeu: 4.514 ± 1.513
0.0ArgMet: 0.0 ± 0.0
1.188ArgAsn: 1.188 ± 0.476
2.851ArgPro: 2.851 ± 0.825
0.95ArgGln: 0.95 ± 0.495
3.089ArgArg: 3.089 ± 0.666
2.376ArgSer: 2.376 ± 0.693
2.851ArgThr: 2.851 ± 0.782
4.514ArgVal: 4.514 ± 0.755
0.475ArgTrp: 0.475 ± 0.248
2.376ArgTyr: 2.376 ± 0.916
0.0ArgXaa: 0.0 ± 0.0
Ser
4.514SerAla: 4.514 ± 1.866
1.188SerCys: 1.188 ± 1.093
4.989SerAsp: 4.989 ± 1.227
2.851SerGlu: 2.851 ± 0.822
3.326SerPhe: 3.326 ± 0.901
3.089SerGly: 3.089 ± 0.785
1.426SerHis: 1.426 ± 0.743
4.039SerIle: 4.039 ± 1.267
6.415SerLys: 6.415 ± 0.692
4.514SerLeu: 4.514 ± 1.008
1.426SerMet: 1.426 ± 0.748
3.089SerAsn: 3.089 ± 0.602
1.663SerPro: 1.663 ± 0.61
1.901SerGln: 1.901 ± 1.028
3.564SerArg: 3.564 ± 0.892
5.94SerSer: 5.94 ± 1.445
6.652SerThr: 6.652 ± 2.156
3.326SerVal: 3.326 ± 0.774
1.188SerTrp: 1.188 ± 0.774
1.663SerTyr: 1.663 ± 0.654
0.0SerXaa: 0.0 ± 0.0
Thr
3.801ThrAla: 3.801 ± 1.705
1.901ThrCys: 1.901 ± 0.622
3.564ThrAsp: 3.564 ± 1.287
3.801ThrGlu: 3.801 ± 1.097
3.089ThrPhe: 3.089 ± 0.659
2.613ThrGly: 2.613 ± 0.345
1.426ThrHis: 1.426 ± 0.323
4.989ThrIle: 4.989 ± 0.633
5.94ThrLys: 5.94 ± 1.593
3.326ThrLeu: 3.326 ± 1.072
2.376ThrMet: 2.376 ± 0.79
1.663ThrAsn: 1.663 ± 0.417
1.901ThrPro: 1.901 ± 0.473
2.376ThrGln: 2.376 ± 1.277
2.376ThrArg: 2.376 ± 0.741
5.227ThrSer: 5.227 ± 1.202
4.752ThrThr: 4.752 ± 1.566
5.464ThrVal: 5.464 ± 0.922
1.188ThrTrp: 1.188 ± 0.405
5.227ThrTyr: 5.227 ± 1.337
0.0ThrXaa: 0.0 ± 0.0
Val
5.227ValAla: 5.227 ± 1.185
0.95ValCys: 0.95 ± 0.411
5.464ValAsp: 5.464 ± 1.02
2.851ValGlu: 2.851 ± 0.536
1.901ValPhe: 1.901 ± 0.727
2.376ValGly: 2.376 ± 0.519
0.713ValHis: 0.713 ± 0.414
4.752ValIle: 4.752 ± 0.805
3.801ValLys: 3.801 ± 0.841
6.177ValLeu: 6.177 ± 1.619
0.95ValMet: 0.95 ± 0.815
4.277ValAsn: 4.277 ± 0.66
4.039ValPro: 4.039 ± 0.967
2.138ValGln: 2.138 ± 0.632
5.94ValArg: 5.94 ± 0.704
7.128ValSer: 7.128 ± 0.791
3.564ValThr: 3.564 ± 0.739
4.039ValVal: 4.039 ± 0.596
0.713ValTrp: 0.713 ± 0.309
3.326ValTyr: 3.326 ± 0.349
0.0ValXaa: 0.0 ± 0.0
Trp
0.238TrpAla: 0.238 ± 0.124
0.238TrpCys: 0.238 ± 0.283
0.713TrpAsp: 0.713 ± 0.371
0.475TrpGlu: 0.475 ± 0.527
0.475TrpPhe: 0.475 ± 0.527
0.238TrpGly: 0.238 ± 0.344
0.238TrpHis: 0.238 ± 0.124
0.713TrpIle: 0.713 ± 0.371
0.713TrpLys: 0.713 ± 0.371
0.475TrpLeu: 0.475 ± 0.333
0.238TrpMet: 0.238 ± 0.124
0.95TrpAsn: 0.95 ± 0.364
0.475TrpPro: 0.475 ± 0.304
0.475TrpGln: 0.475 ± 0.318
0.238TrpArg: 0.238 ± 0.335
1.188TrpSer: 1.188 ± 0.558
0.475TrpThr: 0.475 ± 0.49
0.95TrpVal: 0.95 ± 0.894
0.0TrpTrp: 0.0 ± 0.0
0.475TrpTyr: 0.475 ± 0.234
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.514TyrAla: 4.514 ± 0.588
0.95TyrCys: 0.95 ± 0.563
2.851TyrAsp: 2.851 ± 1.492
3.089TyrGlu: 3.089 ± 0.744
3.089TyrPhe: 3.089 ± 1.546
2.376TyrGly: 2.376 ± 0.46
1.426TyrHis: 1.426 ± 0.811
1.663TyrIle: 1.663 ± 0.68
2.613TyrLys: 2.613 ± 0.597
3.564TyrLeu: 3.564 ± 1.139
1.188TyrMet: 1.188 ± 0.466
2.851TyrAsn: 2.851 ± 0.665
1.901TyrPro: 1.901 ± 0.668
1.426TyrGln: 1.426 ± 0.384
1.426TyrArg: 1.426 ± 0.413
2.613TyrSer: 2.613 ± 0.884
2.613TyrThr: 2.613 ± 1.177
2.138TyrVal: 2.138 ± 0.798
0.0TyrTrp: 0.0 ± 0.0
1.663TyrTyr: 1.663 ± 0.809
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (4210 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski