Amino acid dipepetide frequency for Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.384AlaAla: 6.384 ± 0.1	0.923AlaCys: 0.923 ± 0.026	4.375AlaAsp: 4.375 ± 0.06	4.887AlaGlu: 4.887 ± 0.063	3.333AlaPhe: 3.333 ± 0.047	5.341AlaGly: 5.341 ± 0.079	1.549AlaHis: 1.549 ± 0.03	6.359AlaIle: 6.359 ± 0.075	5.458AlaLys: 5.458 ± 0.07	9.138AlaLeu: 9.138 ± 0.091	2.322AlaMet: 2.322 ± 0.041	3.969AlaAsn: 3.969 ± 0.052	2.451AlaPro: 2.451 ± 0.05	3.714AlaGln: 3.714 ± 0.057	2.887AlaArg: 2.887 ± 0.048	5.362AlaSer: 5.362 ± 0.061	4.445AlaThr: 4.445 ± 0.059	5.211AlaVal: 5.211 ± 0.067	0.834AlaTrp: 0.834 ± 0.02	2.277AlaTyr: 2.277 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	0.723CysAla: 0.723 ± 0.019	0.17CysCys: 0.17 ± 0.011	0.586CysAsp: 0.586 ± 0.02	0.506CysGlu: 0.506 ± 0.017	0.495CysPhe: 0.495 ± 0.018	0.775CysGly: 0.775 ± 0.02	0.334CysHis: 0.334 ± 0.018	0.656CysIle: 0.656 ± 0.021	0.497CysLys: 0.497 ± 0.021	1.019CysLeu: 1.019 ± 0.025	0.212CysMet: 0.212 ± 0.013	0.425CysAsn: 0.425 ± 0.016	0.438CysPro: 0.438 ± 0.017	0.587CysGln: 0.587 ± 0.021	0.407CysArg: 0.407 ± 0.018	0.763CysSer: 0.763 ± 0.023	0.464CysThr: 0.464 ± 0.019	0.592CysVal: 0.592 ± 0.02	0.132CysTrp: 0.132 ± 0.01	0.328CysTyr: 0.328 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.971AspAla: 3.971 ± 0.06	0.56AspCys: 0.56 ± 0.021	3.447AspAsp: 3.447 ± 0.067	3.854AspGlu: 3.854 ± 0.057	2.773AspPhe: 2.773 ± 0.051	3.456AspGly: 3.456 ± 0.079	1.036AspHis: 1.036 ± 0.025	4.679AspIle: 4.679 ± 0.054	3.851AspLys: 3.851 ± 0.053	5.163AspLeu: 5.163 ± 0.055	1.316AspMet: 1.316 ± 0.032	3.142AspAsn: 3.142 ± 0.051	1.653AspPro: 1.653 ± 0.037	1.753AspGln: 1.753 ± 0.032	1.832AspArg: 1.832 ± 0.035	3.614AspSer: 3.614 ± 0.06	2.725AspThr: 2.725 ± 0.057	3.779AspVal: 3.779 ± 0.048	0.749AspTrp: 0.749 ± 0.026	2.171AspTyr: 2.171 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	4.26GluAla: 4.26 ± 0.059	0.452GluCys: 0.452 ± 0.015	2.772GluAsp: 2.772 ± 0.045	3.426GluGlu: 3.426 ± 0.058	2.47GluPhe: 2.47 ± 0.042	3.152GluGly: 3.152 ± 0.045	1.593GluHis: 1.593 ± 0.039	4.13GluIle: 4.13 ± 0.065	4.061GluLys: 4.061 ± 0.056	6.808GluLeu: 6.808 ± 0.082	1.482GluMet: 1.482 ± 0.031	3.183GluAsn: 3.183 ± 0.053	1.633GluPro: 1.633 ± 0.035	4.27GluGln: 4.27 ± 0.067	2.52GluArg: 2.52 ± 0.044	3.752GluSer: 3.752 ± 0.048	2.855GluThr: 2.855 ± 0.048	4.019GluVal: 4.019 ± 0.054	0.557GluTrp: 0.557 ± 0.018	1.72GluTyr: 1.72 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.391PheAla: 3.391 ± 0.061	0.513PheCys: 0.513 ± 0.019	2.901PheAsp: 2.901 ± 0.044	2.486PheGlu: 2.486 ± 0.041	1.961PhePhe: 1.961 ± 0.044	3.074PheGly: 3.074 ± 0.043	0.809PheHis: 0.809 ± 0.021	3.59PheIle: 3.59 ± 0.057	2.341PheLys: 2.341 ± 0.039	3.546PheLeu: 3.546 ± 0.06	0.984PheMet: 0.984 ± 0.031	2.429PheAsn: 2.429 ± 0.04	1.389PhePro: 1.389 ± 0.028	1.248PheGln: 1.248 ± 0.028	1.322PheArg: 1.322 ± 0.031	4.043PheSer: 4.043 ± 0.058	2.873PheThr: 2.873 ± 0.045	2.665PheVal: 2.665 ± 0.039	0.508PheTrp: 0.508 ± 0.017	1.59PheTyr: 1.59 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	4.723GlyAla: 4.723 ± 0.078	0.812GlyCys: 0.812 ± 0.028	3.67GlyAsp: 3.67 ± 0.06	3.944GlyGlu: 3.944 ± 0.057	3.284GlyPhe: 3.284 ± 0.057	4.344GlyGly: 4.344 ± 0.074	1.469GlyHis: 1.469 ± 0.035	4.655GlyIle: 4.655 ± 0.058	4.047GlyLys: 4.047 ± 0.059	6.435GlyLeu: 6.435 ± 0.063	1.774GlyMet: 1.774 ± 0.039	2.83GlyAsn: 2.83 ± 0.057	1.429GlyPro: 1.429 ± 0.034	2.653GlyGln: 2.653 ± 0.043	2.445GlyArg: 2.445 ± 0.038	4.007GlySer: 4.007 ± 0.056	3.242GlyThr: 3.242 ± 0.062	4.632GlyVal: 4.632 ± 0.059	0.79GlyTrp: 0.79 ± 0.025	2.503GlyTyr: 2.503 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	1.446HisAla: 1.446 ± 0.031	0.344HisCys: 0.344 ± 0.017	1.139HisAsp: 1.139 ± 0.027	1.08HisGlu: 1.08 ± 0.03	1.144HisPhe: 1.144 ± 0.029	1.513HisGly: 1.513 ± 0.039	0.647HisHis: 0.647 ± 0.023	1.448HisIle: 1.448 ± 0.027	1.154HisLys: 1.154 ± 0.029	2.221HisLeu: 2.221 ± 0.04	0.437HisMet: 0.437 ± 0.018	0.972HisAsn: 0.972 ± 0.025	0.96HisPro: 0.96 ± 0.022	1.257HisGln: 1.257 ± 0.035	0.85HisArg: 0.85 ± 0.025	1.438HisSer: 1.438 ± 0.036	0.99HisThr: 0.99 ± 0.027	1.23HisVal: 1.23 ± 0.034	0.374HisTrp: 0.374 ± 0.02	0.857HisTyr: 0.857 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.833IleAla: 6.833 ± 0.075	0.703IleCys: 0.703 ± 0.027	4.858IleAsp: 4.858 ± 0.062	5.016IleGlu: 5.016 ± 0.07	2.728IlePhe: 2.728 ± 0.05	4.59IleGly: 4.59 ± 0.061	1.329IleHis: 1.329 ± 0.034	4.986IleIle: 4.986 ± 0.071	4.52IleLys: 4.52 ± 0.062	5.728IleLeu: 5.728 ± 0.074	1.452IleMet: 1.452 ± 0.031	4.257IleAsn: 4.257 ± 0.062	2.638IlePro: 2.638 ± 0.042	2.158IleGln: 2.158 ± 0.038	2.479IleArg: 2.479 ± 0.041	5.845IleSer: 5.845 ± 0.072	4.625IleThr: 4.625 ± 0.056	4.283IleVal: 4.283 ± 0.054	0.627IleTrp: 0.627 ± 0.022	1.967IleTyr: 1.967 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	5.242LysAla: 5.242 ± 0.071	0.385LysCys: 0.385 ± 0.016	2.989LysAsp: 2.989 ± 0.048	3.645LysGlu: 3.645 ± 0.06	1.983LysPhe: 1.983 ± 0.041	3.295LysGly: 3.295 ± 0.053	1.398LysHis: 1.398 ± 0.031	4.07LysIle: 4.07 ± 0.061	4.012LysLys: 4.012 ± 0.069	6.042LysLeu: 6.042 ± 0.072	1.552LysMet: 1.552 ± 0.029	3.357LysAsn: 3.357 ± 0.052	2.271LysPro: 2.271 ± 0.04	3.263LysGln: 3.263 ± 0.052	2.593LysArg: 2.593 ± 0.046	4.116LysSer: 4.116 ± 0.05	3.557LysThr: 3.557 ± 0.054	4.334LysVal: 4.334 ± 0.047	0.564LysTrp: 0.564 ± 0.017	1.767LysTyr: 1.767 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	9.892LeuAla: 9.892 ± 0.101	1.023LeuCys: 1.023 ± 0.025	5.354LeuAsp: 5.354 ± 0.077	5.196LeuGlu: 5.196 ± 0.07	4.394LeuPhe: 4.394 ± 0.064	6.404LeuGly: 6.404 ± 0.076	1.92LeuHis: 1.92 ± 0.034	7.062LeuIle: 7.062 ± 0.082	5.769LeuLys: 5.769 ± 0.082	10.889LeuLeu: 10.889 ± 0.139	2.536LeuMet: 2.536 ± 0.047	5.177LeuAsn: 5.177 ± 0.065	4.402LeuPro: 4.402 ± 0.057	3.498LeuGln: 3.498 ± 0.05	3.634LeuArg: 3.634 ± 0.058	8.765LeuSer: 8.765 ± 0.09	6.854LeuThr: 6.854 ± 0.083	6.79LeuVal: 6.79 ± 0.081	1.005LeuTrp: 1.005 ± 0.03	2.69LeuTyr: 2.69 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.247MetAla: 2.247 ± 0.041	0.204MetCys: 0.204 ± 0.011	1.034MetAsp: 1.034 ± 0.029	1.109MetGlu: 1.109 ± 0.025	0.937MetPhe: 0.937 ± 0.024	1.498MetGly: 1.498 ± 0.036	0.483MetHis: 0.483 ± 0.018	1.527MetIle: 1.527 ± 0.03	1.54MetLys: 1.54 ± 0.031	2.687MetLeu: 2.687 ± 0.039	0.715MetMet: 0.715 ± 0.023	1.216MetAsn: 1.216 ± 0.027	1.188MetPro: 1.188 ± 0.029	1.025MetGln: 1.025 ± 0.026	0.965MetArg: 0.965 ± 0.025	1.911MetSer: 1.911 ± 0.032	1.615MetThr: 1.615 ± 0.035	1.575MetVal: 1.575 ± 0.036	0.211MetTrp: 0.211 ± 0.014	0.544MetTyr: 0.544 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.668AsnAla: 3.668 ± 0.055	0.482AsnCys: 0.482 ± 0.018	2.924AsnAsp: 2.924 ± 0.051	3.147AsnGlu: 3.147 ± 0.052	2.066AsnPhe: 2.066 ± 0.038	3.086AsnGly: 3.086 ± 0.055	1.101AsnHis: 1.101 ± 0.024	3.947AsnIle: 3.947 ± 0.051	3.598AsnLys: 3.598 ± 0.055	4.563AsnLeu: 4.563 ± 0.059	1.101AsnMet: 1.101 ± 0.029	3.109AsnAsn: 3.109 ± 0.056	1.912AsnPro: 1.912 ± 0.042	2.281AsnGln: 2.281 ± 0.046	1.948AsnArg: 1.948 ± 0.038	3.55AsnSer: 3.55 ± 0.059	2.887AsnThr: 2.887 ± 0.051	2.935AsnVal: 2.935 ± 0.05	0.635AsnTrp: 0.635 ± 0.02	1.722AsnTyr: 1.722 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	2.667ProAla: 2.667 ± 0.054	0.329ProCys: 0.329 ± 0.015	2.035ProAsp: 2.035 ± 0.049	2.65ProGlu: 2.65 ± 0.049	1.656ProPhe: 1.656 ± 0.031	1.972ProGly: 1.972 ± 0.042	0.73ProHis: 0.73 ± 0.025	2.551ProIle: 2.551 ± 0.04	2.11ProLys: 2.11 ± 0.045	3.779ProLeu: 3.779 ± 0.055	0.843ProMet: 0.843 ± 0.026	1.686ProAsn: 1.686 ± 0.03	0.922ProPro: 0.922 ± 0.034	1.429ProGln: 1.429 ± 0.027	1.136ProArg: 1.136 ± 0.028	2.378ProSer: 2.378 ± 0.038	1.965ProThr: 1.965 ± 0.039	2.61ProVal: 2.61 ± 0.046	0.449ProTrp: 0.449 ± 0.02	1.157ProTyr: 1.157 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.16GlnAla: 4.16 ± 0.064	0.413GlnCys: 0.413 ± 0.018	2.033GlnAsp: 2.033 ± 0.038	2.348GlnGlu: 2.348 ± 0.045	1.72GlnPhe: 1.72 ± 0.038	3.099GlnGly: 3.099 ± 0.051	1.199GlnHis: 1.199 ± 0.035	2.509GlnIle: 2.509 ± 0.041	2.27GlnLys: 2.27 ± 0.043	5.447GlnLeu: 5.447 ± 0.073	1.004GlnMet: 1.004 ± 0.028	1.756GlnAsn: 1.756 ± 0.035	1.441GlnPro: 1.441 ± 0.032	3.311GlnGln: 3.311 ± 0.081	1.946GlnArg: 1.946 ± 0.04	2.911GlnSer: 2.911 ± 0.048	2.203GlnThr: 2.203 ± 0.042	3.305GlnVal: 3.305 ± 0.052	0.67GlnTrp: 0.67 ± 0.022	1.395GlnTyr: 1.395 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.776ArgAla: 2.776 ± 0.045	0.354ArgCys: 0.354 ± 0.015	1.954ArgAsp: 1.954 ± 0.035	2.294ArgGlu: 2.294 ± 0.045	1.917ArgPhe: 1.917 ± 0.04	2.199ArgGly: 2.199 ± 0.038	0.838ArgHis: 0.838 ± 0.025	2.661ArgIle: 2.661 ± 0.045	2.162ArgLys: 2.162 ± 0.04	4.172ArgLeu: 4.172 ± 0.057	0.995ArgMet: 0.995 ± 0.027	1.76ArgAsn: 1.76 ± 0.035	1.239ArgPro: 1.239 ± 0.03	1.738ArgGln: 1.738 ± 0.035	1.673ArgArg: 1.673 ± 0.033	2.314ArgSer: 2.314 ± 0.045	1.825ArgThr: 1.825 ± 0.033	2.653ArgVal: 2.653 ± 0.048	0.501ArgTrp: 0.501 ± 0.02	1.467ArgTyr: 1.467 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.75SerAla: 5.75 ± 0.065	0.721SerCys: 0.721 ± 0.025	4.063SerAsp: 4.063 ± 0.058	4.203SerGlu: 4.203 ± 0.07	3.438SerPhe: 3.438 ± 0.042	4.885SerGly: 4.885 ± 0.066	1.623SerHis: 1.623 ± 0.032	5.102SerIle: 5.102 ± 0.065	4.065SerLys: 4.065 ± 0.061	7.74SerLeu: 7.74 ± 0.086	1.682SerMet: 1.682 ± 0.034	3.418SerAsn: 3.418 ± 0.051	2.572SerPro: 2.572 ± 0.04	3.166SerGln: 3.166 ± 0.046	2.571SerArg: 2.571 ± 0.041	5.29SerSer: 5.29 ± 0.07	3.948SerThr: 3.948 ± 0.057	4.658SerVal: 4.658 ± 0.061	0.78SerTrp: 0.78 ± 0.02	2.418SerTyr: 2.418 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	4.608ThrAla: 4.608 ± 0.06	0.49ThrCys: 0.49 ± 0.016	3.228ThrAsp: 3.228 ± 0.061	3.345ThrGlu: 3.345 ± 0.045	2.364ThrPhe: 2.364 ± 0.045	4.098ThrGly: 4.098 ± 0.058	1.099ThrHis: 1.099 ± 0.027	3.992ThrIle: 3.992 ± 0.057	3.039ThrLys: 3.039 ± 0.046	6.405ThrLeu: 6.405 ± 0.07	1.228ThrMet: 1.228 ± 0.029	2.595ThrAsn: 2.595 ± 0.041	2.504ThrPro: 2.504 ± 0.039	2.37ThrGln: 2.37 ± 0.043	1.943ThrArg: 1.943 ± 0.039	3.96ThrSer: 3.96 ± 0.058	3.181ThrThr: 3.181 ± 0.05	3.732ThrVal: 3.732 ± 0.058	0.606ThrTrp: 0.606 ± 0.02	1.53ThrTyr: 1.53 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	5.565ValAla: 5.565 ± 0.069	0.698ValCys: 0.698 ± 0.021	4.032ValAsp: 4.032 ± 0.06	4.186ValGlu: 4.186 ± 0.056	2.804ValPhe: 2.804 ± 0.042	4.175ValGly: 4.175 ± 0.069	1.16ValHis: 1.16 ± 0.03	5.192ValIle: 5.192 ± 0.063	3.912ValLys: 3.912 ± 0.053	6.314ValLeu: 6.314 ± 0.068	1.708ValMet: 1.708 ± 0.036	3.533ValAsn: 3.533 ± 0.052	2.235ValPro: 2.235 ± 0.04	2.082ValGln: 2.082 ± 0.04	2.286ValArg: 2.286 ± 0.04	4.927ValSer: 4.927 ± 0.059	4.078ValThr: 4.078 ± 0.061	4.739ValVal: 4.739 ± 0.065	0.652ValTrp: 0.652 ± 0.02	1.867ValTyr: 1.867 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.707TrpAla: 0.707 ± 0.025	0.132TrpCys: 0.132 ± 0.009	0.507TrpAsp: 0.507 ± 0.019	0.425TrpGlu: 0.425 ± 0.018	0.566TrpPhe: 0.566 ± 0.022	0.713TrpGly: 0.713 ± 0.024	0.359TrpHis: 0.359 ± 0.017	0.559TrpIle: 0.559 ± 0.022	0.439TrpLys: 0.439 ± 0.019	1.668TrpLeu: 1.668 ± 0.04	0.268TrpMet: 0.268 ± 0.013	0.44TrpAsn: 0.44 ± 0.016	0.441TrpPro: 0.441 ± 0.016	1.111TrpGln: 1.111 ± 0.029	0.553TrpArg: 0.553 ± 0.018	0.72TrpSer: 0.72 ± 0.021	0.451TrpThr: 0.451 ± 0.023	0.686TrpVal: 0.686 ± 0.022	0.16TrpTrp: 0.16 ± 0.011	0.357TrpTyr: 0.357 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.205TyrAla: 2.205 ± 0.036	0.405TyrCys: 0.405 ± 0.017	1.622TyrAsp: 1.622 ± 0.037	1.367TyrGlu: 1.367 ± 0.03	1.628TyrPhe: 1.628 ± 0.042	2.019TyrGly: 2.019 ± 0.039	0.826TyrHis: 0.826 ± 0.022	1.946TyrIle: 1.946 ± 0.033	1.595TyrLys: 1.595 ± 0.035	3.487TyrLeu: 3.487 ± 0.05	0.621TyrMet: 0.621 ± 0.02	1.408TyrAsn: 1.408 ± 0.036	1.337TyrPro: 1.337 ± 0.029	2.225TyrGln: 2.225 ± 0.042	1.503TyrArg: 1.503 ± 0.031	2.429TyrSer: 2.429 ± 0.044	1.532TyrThr: 1.532 ± 0.03	1.716TyrVal: 1.716 ± 0.035	0.458TyrTrp: 0.458 ± 0.021	1.145TyrTyr: 1.145 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4872 proteins (1504478 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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