Amino acid dipepetide frequency for Quisquiliibacterium sp. CC-CFT501

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.834AlaAla: 20.834 ± 0.186	1.346AlaCys: 1.346 ± 0.037	7.232AlaAsp: 7.232 ± 0.082	7.558AlaGlu: 7.558 ± 0.106	4.472AlaPhe: 4.472 ± 0.058	13.563AlaGly: 13.563 ± 0.132	2.382AlaHis: 2.382 ± 0.048	6.562AlaIle: 6.562 ± 0.071	3.008AlaLys: 3.008 ± 0.078	15.584AlaLeu: 15.584 ± 0.142	3.619AlaMet: 3.619 ± 0.056	2.473AlaAsn: 2.473 ± 0.051	6.996AlaPro: 6.996 ± 0.092	4.534AlaGln: 4.534 ± 0.062	11.937AlaArg: 11.937 ± 0.119	7.098AlaSer: 7.098 ± 0.081	5.88AlaThr: 5.88 ± 0.078	9.482AlaVal: 9.482 ± 0.091	2.205AlaTrp: 2.205 ± 0.046	2.164AlaTyr: 2.164 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.205CysAla: 1.205 ± 0.027	0.099CysCys: 0.099 ± 0.01	0.542CysAsp: 0.542 ± 0.021	0.535CysGlu: 0.535 ± 0.019	0.296CysPhe: 0.296 ± 0.016	0.979CysGly: 0.979 ± 0.026	0.245CysHis: 0.245 ± 0.014	0.327CysIle: 0.327 ± 0.015	0.165CysLys: 0.165 ± 0.012	0.793CysLeu: 0.793 ± 0.03	0.173CysMet: 0.173 ± 0.011	0.207CysAsn: 0.207 ± 0.014	0.52CysPro: 0.52 ± 0.023	0.176CysGln: 0.176 ± 0.014	0.686CysArg: 0.686 ± 0.027	0.453CysSer: 0.453 ± 0.018	0.397CysThr: 0.397 ± 0.022	0.677CysVal: 0.677 ± 0.022	0.118CysTrp: 0.118 ± 0.012	0.182CysTyr: 0.182 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.643AspAla: 7.643 ± 0.089	0.523AspCys: 0.523 ± 0.022	2.954AspAsp: 2.954 ± 0.061	3.727AspGlu: 3.727 ± 0.067	1.951AspPhe: 1.951 ± 0.046	4.779AspGly: 4.779 ± 0.067	0.972AspHis: 0.972 ± 0.028	2.091AspIle: 2.091 ± 0.049	1.235AspLys: 1.235 ± 0.04	5.397AspLeu: 5.397 ± 0.077	1.079AspMet: 1.079 ± 0.034	0.92AspAsn: 0.92 ± 0.03	3.809AspPro: 3.809 ± 0.058	1.225AspGln: 1.225 ± 0.033	4.76AspArg: 4.76 ± 0.073	2.265AspSer: 2.265 ± 0.044	2.381AspThr: 2.381 ± 0.041	3.497AspVal: 3.497 ± 0.062	1.075AspTrp: 1.075 ± 0.034	1.32AspTyr: 1.32 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	8.014GluAla: 8.014 ± 0.096	0.359GluCys: 0.359 ± 0.017	2.327GluAsp: 2.327 ± 0.042	2.39GluGlu: 2.39 ± 0.059	1.82GluPhe: 1.82 ± 0.034	4.122GluGly: 4.122 ± 0.061	1.302GluHis: 1.302 ± 0.036	3.078GluIle: 3.078 ± 0.052	1.663GluLys: 1.663 ± 0.045	6.165GluLeu: 6.165 ± 0.07	1.248GluMet: 1.248 ± 0.032	1.248GluAsn: 1.248 ± 0.034	3.144GluPro: 3.144 ± 0.063	2.238GluGln: 2.238 ± 0.047	6.159GluArg: 6.159 ± 0.096	2.838GluSer: 2.838 ± 0.052	2.652GluThr: 2.652 ± 0.048	4.228GluVal: 4.228 ± 0.069	0.702GluTrp: 0.702 ± 0.025	1.003GluTyr: 1.003 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.686PheAla: 4.686 ± 0.064	0.369PheCys: 0.369 ± 0.017	2.575PheAsp: 2.575 ± 0.048	2.306PheGlu: 2.306 ± 0.044	1.288PhePhe: 1.288 ± 0.037	3.822PheGly: 3.822 ± 0.056	0.685PheHis: 0.685 ± 0.026	1.16PheIle: 1.16 ± 0.032	0.709PheLys: 0.709 ± 0.025	3.021PheLeu: 3.021 ± 0.051	0.68PheMet: 0.68 ± 0.026	0.834PheAsn: 0.834 ± 0.029	1.521PhePro: 1.521 ± 0.035	0.855PheGln: 0.855 ± 0.029	2.373PheArg: 2.373 ± 0.039	1.817PheSer: 1.817 ± 0.041	1.663PheThr: 1.663 ± 0.04	3.154PheVal: 3.154 ± 0.053	0.509PheTrp: 0.509 ± 0.024	0.737PheTyr: 0.737 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	11.152GlyAla: 11.152 ± 0.119	0.92GlyCys: 0.92 ± 0.032	4.367GlyAsp: 4.367 ± 0.07	5.239GlyGlu: 5.239 ± 0.078	3.489GlyPhe: 3.489 ± 0.055	7.876GlyGly: 7.876 ± 0.129	1.979GlyHis: 1.979 ± 0.04	4.282GlyIle: 4.282 ± 0.062	2.954GlyLys: 2.954 ± 0.055	9.655GlyLeu: 9.655 ± 0.091	2.483GlyMet: 2.483 ± 0.048	1.853GlyAsn: 1.853 ± 0.044	3.911GlyPro: 3.911 ± 0.07	2.882GlyGln: 2.882 ± 0.048	7.351GlyArg: 7.351 ± 0.087	4.768GlySer: 4.768 ± 0.064	4.132GlyThr: 4.132 ± 0.072	6.598GlyVal: 6.598 ± 0.073	1.66GlyTrp: 1.66 ± 0.042	2.175GlyTyr: 2.175 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.704HisAla: 2.704 ± 0.048	0.256HisCys: 0.256 ± 0.013	1.162HisAsp: 1.162 ± 0.032	1.183HisGlu: 1.183 ± 0.029	0.704HisPhe: 0.704 ± 0.024	2.072HisGly: 2.072 ± 0.047	0.511HisHis: 0.511 ± 0.023	0.632HisIle: 0.632 ± 0.024	0.38HisLys: 0.38 ± 0.017	1.975HisLeu: 1.975 ± 0.044	0.378HisMet: 0.378 ± 0.018	0.374HisAsn: 0.374 ± 0.018	1.487HisPro: 1.487 ± 0.04	0.523HisGln: 0.523 ± 0.022	1.734HisArg: 1.734 ± 0.044	0.859HisSer: 0.859 ± 0.025	0.74HisThr: 0.74 ± 0.021	1.43HisVal: 1.43 ± 0.04	0.357HisTrp: 0.357 ± 0.017	0.514HisTyr: 0.514 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.059IleAla: 7.059 ± 0.084	0.366IleCys: 0.366 ± 0.019	3.34IleAsp: 3.34 ± 0.057	3.525IleGlu: 3.525 ± 0.064	1.27IlePhe: 1.27 ± 0.035	4.778IleGly: 4.778 ± 0.061	0.78IleHis: 0.78 ± 0.024	1.224IleIle: 1.224 ± 0.043	0.961IleLys: 0.961 ± 0.03	3.528IleLeu: 3.528 ± 0.062	0.725IleMet: 0.725 ± 0.026	0.951IleAsn: 0.951 ± 0.031	2.148IlePro: 2.148 ± 0.043	0.986IleGln: 0.986 ± 0.028	3.271IleArg: 3.271 ± 0.045	1.856IleSer: 1.856 ± 0.043	1.924IleThr: 1.924 ± 0.049	4.366IleVal: 4.366 ± 0.069	0.497IleTrp: 0.497 ± 0.024	0.768IleTyr: 0.768 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.447LysAla: 3.447 ± 0.067	0.139LysCys: 0.139 ± 0.012	1.135LysAsp: 1.135 ± 0.035	1.133LysGlu: 1.133 ± 0.039	0.702LysPhe: 0.702 ± 0.027	2.027LysGly: 2.027 ± 0.043	0.505LysHis: 0.505 ± 0.021	1.249LysIle: 1.249 ± 0.045	0.917LysLys: 0.917 ± 0.038	2.901LysLeu: 2.901 ± 0.049	0.647LysMet: 0.647 ± 0.028	0.56LysAsn: 0.56 ± 0.018	1.753LysPro: 1.753 ± 0.044	0.827LysGln: 0.827 ± 0.03	2.112LysArg: 2.112 ± 0.046	1.299LysSer: 1.299 ± 0.04	1.321LysThr: 1.321 ± 0.038	2.102LysVal: 2.102 ± 0.051	0.303LysTrp: 0.303 ± 0.017	0.513LysTyr: 0.513 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	17.125LeuAla: 17.125 ± 0.161	0.843LeuCys: 0.843 ± 0.028	6.046LeuAsp: 6.046 ± 0.079	5.67LeuGlu: 5.67 ± 0.078	3.523LeuPhe: 3.523 ± 0.072	8.987LeuGly: 8.987 ± 0.088	1.984LeuHis: 1.984 ± 0.04	4.223LeuIle: 4.223 ± 0.069	2.816LeuLys: 2.816 ± 0.054	11.208LeuLeu: 11.208 ± 0.139	2.303LeuMet: 2.303 ± 0.045	2.14LeuAsn: 2.14 ± 0.043	6.401LeuPro: 6.401 ± 0.084	2.938LeuGln: 2.938 ± 0.05	8.842LeuArg: 8.842 ± 0.107	5.875LeuSer: 5.875 ± 0.078	4.481LeuThr: 4.481 ± 0.064	8.218LeuVal: 8.218 ± 0.085	1.204LeuTrp: 1.204 ± 0.036	1.841LeuTyr: 1.841 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.877MetAla: 2.877 ± 0.046	0.164MetCys: 0.164 ± 0.012	0.934MetAsp: 0.934 ± 0.028	0.809MetGlu: 0.809 ± 0.024	0.736MetPhe: 0.736 ± 0.029	1.668MetGly: 1.668 ± 0.046	0.461MetHis: 0.461 ± 0.019	1.193MetIle: 1.193 ± 0.035	1.01MetLys: 1.01 ± 0.032	2.766MetLeu: 2.766 ± 0.047	0.546MetMet: 0.546 ± 0.023	0.759MetAsn: 0.759 ± 0.026	1.616MetPro: 1.616 ± 0.037	0.851MetGln: 0.851 ± 0.027	1.944MetArg: 1.944 ± 0.044	1.614MetSer: 1.614 ± 0.035	1.447MetThr: 1.447 ± 0.035	1.578MetVal: 1.578 ± 0.04	0.2MetTrp: 0.2 ± 0.015	0.361MetTyr: 0.361 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.686AsnAla: 2.686 ± 0.05	0.242AsnCys: 0.242 ± 0.014	1.039AsnAsp: 1.039 ± 0.031	1.026AsnGlu: 1.026 ± 0.028	0.751AsnPhe: 0.751 ± 0.026	1.857AsnGly: 1.857 ± 0.046	0.395AsnHis: 0.395 ± 0.018	0.853AsnIle: 0.853 ± 0.031	0.497AsnLys: 0.497 ± 0.022	2.391AsnLeu: 2.391 ± 0.05	0.451AsnMet: 0.451 ± 0.022	0.486AsnAsn: 0.486 ± 0.023	1.619AsnPro: 1.619 ± 0.034	0.58AsnGln: 0.58 ± 0.022	1.73AsnArg: 1.73 ± 0.035	0.785AsnSer: 0.785 ± 0.028	0.986AsnThr: 0.986 ± 0.028	1.592AsnVal: 1.592 ± 0.041	0.361AsnTrp: 0.361 ± 0.019	0.466AsnTyr: 0.466 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	8.442ProAla: 8.442 ± 0.114	0.35ProCys: 0.35 ± 0.015	3.704ProAsp: 3.704 ± 0.059	3.756ProGlu: 3.756 ± 0.057	1.854ProPhe: 1.854 ± 0.04	5.734ProGly: 5.734 ± 0.083	1.043ProHis: 1.043 ± 0.034	2.255ProIle: 2.255 ± 0.044	1.395ProLys: 1.395 ± 0.039	5.229ProLeu: 5.229 ± 0.066	1.356ProMet: 1.356 ± 0.036	1.083ProAsn: 1.083 ± 0.029	3.021ProPro: 3.021 ± 0.059	1.722ProGln: 1.722 ± 0.042	3.789ProArg: 3.789 ± 0.064	2.628ProSer: 2.628 ± 0.05	2.303ProThr: 2.303 ± 0.048	4.657ProVal: 4.657 ± 0.064	0.837ProTrp: 0.837 ± 0.029	1.058ProTyr: 1.058 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.883GlnAla: 4.883 ± 0.073	0.218GlnCys: 0.218 ± 0.013	1.162GlnAsp: 1.162 ± 0.029	1.192GlnGlu: 1.192 ± 0.03	1.006GlnPhe: 1.006 ± 0.031	2.466GlnGly: 2.466 ± 0.047	0.601GlnHis: 0.601 ± 0.022	1.427GlnIle: 1.427 ± 0.038	0.826GlnLys: 0.826 ± 0.026	3.108GlnLeu: 3.108 ± 0.059	0.776GlnMet: 0.776 ± 0.024	0.522GlnAsn: 0.522 ± 0.024	1.809GlnPro: 1.809 ± 0.045	1.213GlnGln: 1.213 ± 0.036	2.771GlnArg: 2.771 ± 0.051	1.369GlnSer: 1.369 ± 0.042	1.318GlnThr: 1.318 ± 0.035	2.54GlnVal: 2.54 ± 0.048	0.453GlnTrp: 0.453 ± 0.02	0.597GlnTyr: 0.597 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	10.326ArgAla: 10.326 ± 0.116	0.725ArgCys: 0.725 ± 0.024	4.329ArgAsp: 4.329 ± 0.07	5.741ArgGlu: 5.741 ± 0.074	3.345ArgPhe: 3.345 ± 0.06	6.01ArgGly: 6.01 ± 0.07	2.06ArgHis: 2.06 ± 0.046	4.396ArgIle: 4.396 ± 0.059	2.176ArgLys: 2.176 ± 0.046	9.371ArgLeu: 9.371 ± 0.117	2.22ArgMet: 2.22 ± 0.044	1.777ArgAsn: 1.777 ± 0.037	4.448ArgPro: 4.448 ± 0.071	2.839ArgGln: 2.839 ± 0.051	7.358ArgArg: 7.358 ± 0.101	3.92ArgSer: 3.92 ± 0.07	3.434ArgThr: 3.434 ± 0.053	5.955ArgVal: 5.955 ± 0.085	1.396ArgTrp: 1.396 ± 0.04	1.913ArgTyr: 1.913 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.302SerAla: 6.302 ± 0.075	0.382SerCys: 0.382 ± 0.017	2.271SerAsp: 2.271 ± 0.042	2.373SerGlu: 2.373 ± 0.045	1.93SerPhe: 1.93 ± 0.04	5.377SerGly: 5.377 ± 0.074	0.976SerHis: 0.976 ± 0.029	2.333SerIle: 2.333 ± 0.045	1.182SerLys: 1.182 ± 0.039	5.52SerLeu: 5.52 ± 0.078	1.219SerMet: 1.219 ± 0.028	1.072SerAsn: 1.072 ± 0.023	3.072SerPro: 3.072 ± 0.06	1.413SerGln: 1.413 ± 0.038	4.148SerArg: 4.148 ± 0.067	2.544SerSer: 2.544 ± 0.048	2.435SerThr: 2.435 ± 0.043	3.827SerVal: 3.827 ± 0.054	0.728SerTrp: 0.728 ± 0.024	0.95SerTyr: 0.95 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	5.225ThrAla: 5.225 ± 0.068	0.37ThrCys: 0.37 ± 0.019	2.248ThrAsp: 2.248 ± 0.049	2.158ThrGlu: 2.158 ± 0.04	1.391ThrPhe: 1.391 ± 0.041	4.748ThrGly: 4.748 ± 0.075	0.863ThrHis: 0.863 ± 0.026	2.368ThrIle: 2.368 ± 0.049	0.961ThrLys: 0.961 ± 0.033	5.53ThrLeu: 5.53 ± 0.07	1.148ThrMet: 1.148 ± 0.03	0.918ThrAsn: 0.918 ± 0.028	2.845ThrPro: 2.845 ± 0.055	1.219ThrGln: 1.219 ± 0.033	3.405ThrArg: 3.405 ± 0.053	2.12ThrSer: 2.12 ± 0.05	2.143ThrThr: 2.143 ± 0.047	3.921ThrVal: 3.921 ± 0.064	0.629ThrTrp: 0.629 ± 0.026	0.776ThrTyr: 0.776 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	10.512ValAla: 10.512 ± 0.094	0.736ValCys: 0.736 ± 0.026	4.562ValAsp: 4.562 ± 0.068	4.775ValGlu: 4.775 ± 0.071	2.834ValPhe: 2.834 ± 0.058	6.017ValGly: 6.017 ± 0.076	1.487ValHis: 1.487 ± 0.037	3.313ValIle: 3.313 ± 0.066	1.86ValLys: 1.86 ± 0.044	8.015ValLeu: 8.015 ± 0.089	1.725ValMet: 1.725 ± 0.036	1.779ValAsn: 1.779 ± 0.045	4.235ValPro: 4.235 ± 0.058	1.968ValGln: 1.968 ± 0.042	5.971ValArg: 5.971 ± 0.078	4.238ValSer: 4.238 ± 0.057	3.695ValThr: 3.695 ± 0.059	6.614ValVal: 6.614 ± 0.076	1.011ValTrp: 1.011 ± 0.031	1.514ValTyr: 1.514 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.421TrpAla: 1.421 ± 0.037	0.163TrpCys: 0.163 ± 0.012	0.568TrpAsp: 0.568 ± 0.026	0.562TrpGlu: 0.562 ± 0.024	0.6TrpPhe: 0.6 ± 0.022	0.985TrpGly: 0.985 ± 0.034	0.382TrpHis: 0.382 ± 0.019	0.712TrpIle: 0.712 ± 0.026	0.401TrpLys: 0.401 ± 0.019	2.309TrpLeu: 2.309 ± 0.052	0.38TrpMet: 0.38 ± 0.018	0.38TrpAsn: 0.38 ± 0.019	0.781TrpPro: 0.781 ± 0.025	0.642TrpGln: 0.642 ± 0.025	1.505TrpArg: 1.505 ± 0.044	0.775TrpSer: 0.775 ± 0.028	0.695TrpThr: 0.695 ± 0.024	0.987TrpVal: 0.987 ± 0.029	0.296TrpTrp: 0.296 ± 0.017	0.316TrpTyr: 0.316 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.389TyrAla: 2.389 ± 0.05	0.208TyrCys: 0.208 ± 0.015	1.108TyrAsp: 1.108 ± 0.032	1.041TyrGlu: 1.041 ± 0.029	0.801TyrPhe: 0.801 ± 0.029	1.862TyrGly: 1.862 ± 0.039	0.36TyrHis: 0.36 ± 0.016	0.642TyrIle: 0.642 ± 0.025	0.475TyrLys: 0.475 ± 0.025	2.199TyrLeu: 2.199 ± 0.04	0.378TyrMet: 0.378 ± 0.019	0.457TyrAsn: 0.457 ± 0.019	1.08TyrPro: 1.08 ± 0.032	0.627TyrGln: 0.627 ± 0.025	1.896TyrArg: 1.896 ± 0.044	0.931TyrSer: 0.931 ± 0.03	0.96TyrThr: 0.96 ± 0.031	1.435TyrVal: 1.435 ± 0.039	0.32TyrTrp: 0.32 ± 0.018	0.483TyrTyr: 0.483 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3574 proteins (1175913 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---