Amino acid dipepetide frequency for Mycolicibacterium chitae (Mycobacterium chitae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.039AlaAla: 21.039 ± 0.202	0.97AlaCys: 0.97 ± 0.024	8.77AlaAsp: 8.77 ± 0.077	8.782AlaGlu: 8.782 ± 0.098	3.399AlaPhe: 3.399 ± 0.049	12.004AlaGly: 12.004 ± 0.09	2.486AlaHis: 2.486 ± 0.043	5.125AlaIle: 5.125 ± 0.057	3.059AlaLys: 3.059 ± 0.054	13.468AlaLeu: 13.468 ± 0.121	2.868AlaMet: 2.868 ± 0.042	2.537AlaAsn: 2.537 ± 0.036	6.899AlaPro: 6.899 ± 0.09	4.124AlaGln: 4.124 ± 0.056	8.613AlaArg: 8.613 ± 0.081	5.23AlaSer: 5.23 ± 0.068	7.33AlaThr: 7.33 ± 0.079	11.955AlaVal: 11.955 ± 0.1	1.557AlaTrp: 1.557 ± 0.032	2.324AlaTyr: 2.324 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	1.106CysAla: 1.106 ± 0.027	0.08CysCys: 0.08 ± 0.007	0.496CysAsp: 0.496 ± 0.017	0.437CysGlu: 0.437 ± 0.019	0.225CysPhe: 0.225 ± 0.011	0.917CysGly: 0.917 ± 0.025	0.171CysHis: 0.171 ± 0.01	0.25CysIle: 0.25 ± 0.012	0.12CysLys: 0.12 ± 0.007	0.614CysLeu: 0.614 ± 0.021	0.129CysMet: 0.129 ± 0.009	0.158CysAsn: 0.158 ± 0.01	0.488CysPro: 0.488 ± 0.02	0.205CysGln: 0.205 ± 0.011	0.574CysArg: 0.574 ± 0.022	0.423CysSer: 0.423 ± 0.015	0.463CysThr: 0.463 ± 0.016	0.625CysVal: 0.625 ± 0.018	0.134CysTrp: 0.134 ± 0.008	0.19CysTyr: 0.19 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.806AspAla: 7.806 ± 0.075	0.467AspCys: 0.467 ± 0.015	4.418AspAsp: 4.418 ± 0.067	4.263AspGlu: 4.263 ± 0.059	1.841AspPhe: 1.841 ± 0.032	6.111AspGly: 6.111 ± 0.069	1.374AspHis: 1.374 ± 0.027	2.696AspIle: 2.696 ± 0.05	1.311AspLys: 1.311 ± 0.028	6.225AspLeu: 6.225 ± 0.065	1.01AspMet: 1.01 ± 0.023	1.289AspAsn: 1.289 ± 0.028	4.724AspPro: 4.724 ± 0.057	1.802AspGln: 1.802 ± 0.035	4.622AspArg: 4.622 ± 0.062	2.832AspSer: 2.832 ± 0.044	3.319AspThr: 3.319 ± 0.044	5.14AspVal: 5.14 ± 0.059	0.998AspTrp: 0.998 ± 0.023	1.474AspTyr: 1.474 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	6.666GluAla: 6.666 ± 0.073	0.343GluCys: 0.343 ± 0.015	2.799GluAsp: 2.799 ± 0.05	2.763GluGlu: 2.763 ± 0.051	2.01GluPhe: 2.01 ± 0.036	3.369GluGly: 3.369 ± 0.06	1.641GluHis: 1.641 ± 0.027	2.784GluIle: 2.784 ± 0.045	1.318GluLys: 1.318 ± 0.035	6.942GluLeu: 6.942 ± 0.072	1.08GluMet: 1.08 ± 0.027	1.144GluAsn: 1.144 ± 0.028	3.235GluPro: 3.235 ± 0.051	2.492GluGln: 2.492 ± 0.042	4.527GluArg: 4.527 ± 0.05	2.757GluSer: 2.757 ± 0.045	2.926GluThr: 2.926 ± 0.05	4.83GluVal: 4.83 ± 0.053	0.696GluTrp: 0.696 ± 0.022	1.121GluTyr: 1.121 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.033PheAla: 4.033 ± 0.051	0.329PheCys: 0.329 ± 0.013	2.556PheAsp: 2.556 ± 0.04	1.66PheGlu: 1.66 ± 0.034	1.002PhePhe: 1.002 ± 0.028	3.459PheGly: 3.459 ± 0.046	0.586PheHis: 0.586 ± 0.019	1.067PheIle: 1.067 ± 0.031	0.528PheLys: 0.528 ± 0.021	2.605PheLeu: 2.605 ± 0.04	0.52PheMet: 0.52 ± 0.016	0.753PheAsn: 0.753 ± 0.022	1.458PhePro: 1.458 ± 0.029	0.693PheGln: 0.693 ± 0.022	1.64PheArg: 1.64 ± 0.032	1.699PheSer: 1.699 ± 0.036	2.119PheThr: 2.119 ± 0.041	2.586PheVal: 2.586 ± 0.044	0.462PheTrp: 0.462 ± 0.017	0.742PheTyr: 0.742 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	10.68GlyAla: 10.68 ± 0.099	0.759GlyCys: 0.759 ± 0.023	4.948GlyAsp: 4.948 ± 0.061	4.482GlyGlu: 4.482 ± 0.06	3.021GlyPhe: 3.021 ± 0.044	7.801GlyGly: 7.801 ± 0.119	1.956GlyHis: 1.956 ± 0.037	4.09GlyIle: 4.09 ± 0.055	2.248GlyLys: 2.248 ± 0.037	8.654GlyLeu: 8.654 ± 0.071	2.171GlyMet: 2.171 ± 0.037	1.891GlyAsn: 1.891 ± 0.041	4.782GlyPro: 4.782 ± 0.057	2.826GlyGln: 2.826 ± 0.046	6.248GlyArg: 6.248 ± 0.068	4.987GlySer: 4.987 ± 0.059	5.414GlyThr: 5.414 ± 0.065	7.664GlyVal: 7.664 ± 0.07	1.594GlyTrp: 1.594 ± 0.031	2.369GlyTyr: 2.369 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.339HisAla: 2.339 ± 0.038	0.219HisCys: 0.219 ± 0.011	1.316HisAsp: 1.316 ± 0.028	1.047HisGlu: 1.047 ± 0.029	0.681HisPhe: 0.681 ± 0.022	2.042HisGly: 2.042 ± 0.039	0.626HisHis: 0.626 ± 0.018	0.799HisIle: 0.799 ± 0.022	0.346HisLys: 0.346 ± 0.016	2.09HisLeu: 2.09 ± 0.036	0.335HisMet: 0.335 ± 0.016	0.47HisAsn: 0.47 ± 0.015	1.636HisPro: 1.636 ± 0.037	0.625HisGln: 0.625 ± 0.02	1.889HisArg: 1.889 ± 0.04	1.063HisSer: 1.063 ± 0.025	1.196HisThr: 1.196 ± 0.026	1.592HisVal: 1.592 ± 0.038	0.385HisTrp: 0.385 ± 0.016	0.545HisTyr: 0.545 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.321IleAla: 6.321 ± 0.062	0.407IleCys: 0.407 ± 0.016	3.394IleAsp: 3.394 ± 0.049	2.709IleGlu: 2.709 ± 0.042	1.111IlePhe: 1.111 ± 0.028	4.451IleGly: 4.451 ± 0.061	0.734IleHis: 0.734 ± 0.02	1.518IleIle: 1.518 ± 0.041	0.891IleLys: 0.891 ± 0.026	3.109IleLeu: 3.109 ± 0.044	0.603IleMet: 0.603 ± 0.019	1.15IleAsn: 1.15 ± 0.026	2.392IlePro: 2.392 ± 0.038	0.911IleGln: 0.911 ± 0.024	2.59IleArg: 2.59 ± 0.036	2.233IleSer: 2.233 ± 0.036	2.763IleThr: 2.763 ± 0.042	3.706IleVal: 3.706 ± 0.054	0.474IleTrp: 0.474 ± 0.017	0.796IleTyr: 0.796 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.593LysAla: 2.593 ± 0.046	0.123LysCys: 0.123 ± 0.009	1.11LysAsp: 1.11 ± 0.031	0.944LysGlu: 0.944 ± 0.03	0.662LysPhe: 0.662 ± 0.022	1.514LysGly: 1.514 ± 0.039	0.502LysHis: 0.502 ± 0.017	1.015LysIle: 1.015 ± 0.028	0.651LysLys: 0.651 ± 0.031	2.212LysLeu: 2.212 ± 0.038	0.487LysMet: 0.487 ± 0.018	0.523LysAsn: 0.523 ± 0.022	1.37LysPro: 1.37 ± 0.031	0.698LysGln: 0.698 ± 0.023	1.544LysArg: 1.544 ± 0.033	1.189LysSer: 1.189 ± 0.033	1.346LysThr: 1.346 ± 0.032	2.013LysVal: 2.013 ± 0.041	0.323LysTrp: 0.323 ± 0.014	0.475LysTyr: 0.475 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	14.256LeuAla: 14.256 ± 0.12	0.779LeuCys: 0.779 ± 0.024	6.783LeuAsp: 6.783 ± 0.079	4.679LeuGlu: 4.679 ± 0.057	2.715LeuPhe: 2.715 ± 0.043	9.181LeuGly: 9.181 ± 0.081	2.006LeuHis: 2.006 ± 0.033	4.191LeuIle: 4.191 ± 0.057	1.742LeuLys: 1.742 ± 0.036	9.804LeuLeu: 9.804 ± 0.115	1.768LeuMet: 1.768 ± 0.032	2.115LeuAsn: 2.115 ± 0.036	5.846LeuPro: 5.846 ± 0.068	2.626LeuGln: 2.626 ± 0.041	7.719LeuArg: 7.719 ± 0.087	5.537LeuSer: 5.537 ± 0.073	6.43LeuThr: 6.43 ± 0.062	8.372LeuVal: 8.372 ± 0.082	1.2LeuTrp: 1.2 ± 0.028	1.618LeuTyr: 1.618 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.633MetAla: 2.633 ± 0.042	0.175MetCys: 0.175 ± 0.011	0.889MetAsp: 0.889 ± 0.027	0.705MetGlu: 0.705 ± 0.019	0.672MetPhe: 0.672 ± 0.021	1.473MetGly: 1.473 ± 0.03	0.412MetHis: 0.412 ± 0.017	0.933MetIle: 0.933 ± 0.023	0.448MetLys: 0.448 ± 0.016	2.009MetLeu: 2.009 ± 0.033	0.417MetMet: 0.417 ± 0.015	0.493MetAsn: 0.493 ± 0.018	1.173MetPro: 1.173 ± 0.026	0.557MetGln: 0.557 ± 0.017	1.495MetArg: 1.495 ± 0.029	1.598MetSer: 1.598 ± 0.028	1.86MetThr: 1.86 ± 0.033	1.653MetVal: 1.653 ± 0.032	0.254MetTrp: 0.254 ± 0.012	0.341MetTyr: 0.341 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.565AsnAla: 2.565 ± 0.041	0.17AsnCys: 0.17 ± 0.011	1.214AsnAsp: 1.214 ± 0.028	1.032AsnGlu: 1.032 ± 0.028	0.701AsnPhe: 0.701 ± 0.025	1.95AsnGly: 1.95 ± 0.04	0.451AsnHis: 0.451 ± 0.017	0.971AsnIle: 0.971 ± 0.028	0.453AsnLys: 0.453 ± 0.018	2.12AsnLeu: 2.12 ± 0.039	0.44AsnMet: 0.44 ± 0.019	0.617AsnAsn: 0.617 ± 0.022	1.822AsnPro: 1.822 ± 0.042	0.647AsnGln: 0.647 ± 0.018	1.574AsnArg: 1.574 ± 0.032	1.17AsnSer: 1.17 ± 0.031	1.338AsnThr: 1.338 ± 0.03	1.742AsnVal: 1.742 ± 0.029	0.385AsnTrp: 0.385 ± 0.015	0.558AsnTyr: 0.558 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.842ProAla: 7.842 ± 0.098	0.29ProCys: 0.29 ± 0.013	4.517ProAsp: 4.517 ± 0.053	4.22ProGlu: 4.22 ± 0.063	1.655ProPhe: 1.655 ± 0.031	5.618ProGly: 5.618 ± 0.068	1.207ProHis: 1.207 ± 0.031	2.157ProIle: 2.157 ± 0.037	1.294ProLys: 1.294 ± 0.028	4.955ProLeu: 4.955 ± 0.061	1.229ProMet: 1.229 ± 0.027	1.316ProAsn: 1.316 ± 0.031	3.763ProPro: 3.763 ± 0.087	1.783ProGln: 1.783 ± 0.035	3.534ProArg: 3.534 ± 0.047	2.881ProSer: 2.881 ± 0.046	3.529ProThr: 3.529 ± 0.047	5.164ProVal: 5.164 ± 0.063	0.806ProTrp: 0.806 ± 0.021	1.168ProTyr: 1.168 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.515GlnAla: 3.515 ± 0.042	0.214GlnCys: 0.214 ± 0.012	1.294GlnAsp: 1.294 ± 0.031	1.167GlnGlu: 1.167 ± 0.026	1.004GlnPhe: 1.004 ± 0.025	2.005GlnGly: 2.005 ± 0.036	0.732GlnHis: 0.732 ± 0.023	1.526GlnIle: 1.526 ± 0.027	0.623GlnLys: 0.623 ± 0.023	3.595GlnLeu: 3.595 ± 0.047	0.694GlnMet: 0.694 ± 0.023	0.626GlnAsn: 0.626 ± 0.019	1.815GlnPro: 1.815 ± 0.034	1.366GlnGln: 1.366 ± 0.03	2.894GlnArg: 2.894 ± 0.046	1.431GlnSer: 1.431 ± 0.031	1.61GlnThr: 1.61 ± 0.035	2.595GlnVal: 2.595 ± 0.035	0.598GlnTrp: 0.598 ± 0.018	0.681GlnTyr: 0.681 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.543ArgAla: 8.543 ± 0.085	0.574ArgCys: 0.574 ± 0.021	4.281ArgAsp: 4.281 ± 0.052	3.932ArgGlu: 3.932 ± 0.052	2.392ArgPhe: 2.392 ± 0.037	5.284ArgGly: 5.284 ± 0.064	1.669ArgHis: 1.669 ± 0.034	3.43ArgIle: 3.43 ± 0.047	1.615ArgLys: 1.615 ± 0.035	7.262ArgLeu: 7.262 ± 0.079	1.756ArgMet: 1.756 ± 0.035	1.632ArgAsn: 1.632 ± 0.029	4.012ArgPro: 4.012 ± 0.054	2.238ArgGln: 2.238 ± 0.032	6.542ArgArg: 6.542 ± 0.085	3.813ArgSer: 3.813 ± 0.05	4.235ArgThr: 4.235 ± 0.051	5.542ArgVal: 5.542 ± 0.061	1.32ArgTrp: 1.32 ± 0.034	1.905ArgTyr: 1.905 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.724SerAla: 6.724 ± 0.066	0.403SerCys: 0.403 ± 0.018	3.1SerAsp: 3.1 ± 0.051	2.62SerGlu: 2.62 ± 0.044	1.672SerPhe: 1.672 ± 0.036	5.323SerGly: 5.323 ± 0.061	0.974SerHis: 0.974 ± 0.023	2.109SerIle: 2.109 ± 0.037	1.102SerLys: 1.102 ± 0.03	4.496SerLeu: 4.496 ± 0.06	1.338SerMet: 1.338 ± 0.029	1.066SerAsn: 1.066 ± 0.028	2.903SerPro: 2.903 ± 0.041	1.387SerGln: 1.387 ± 0.028	3.436SerArg: 3.436 ± 0.045	2.848SerSer: 2.848 ± 0.044	3.287SerThr: 3.287 ± 0.048	4.345SerVal: 4.345 ± 0.054	0.892SerTrp: 0.892 ± 0.023	1.263SerTyr: 1.263 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	8.22ThrAla: 8.22 ± 0.081	0.399ThrCys: 0.399 ± 0.016	3.83ThrAsp: 3.83 ± 0.048	3.496ThrGlu: 3.496 ± 0.053	1.818ThrPhe: 1.818 ± 0.037	5.894ThrGly: 5.894 ± 0.07	1.12ThrHis: 1.12 ± 0.028	2.357ThrIle: 2.357 ± 0.039	1.276ThrLys: 1.276 ± 0.032	5.724ThrLeu: 5.724 ± 0.068	1.198ThrMet: 1.198 ± 0.028	1.247ThrAsn: 1.247 ± 0.032	3.795ThrPro: 3.795 ± 0.049	1.514ThrGln: 1.514 ± 0.032	3.563ThrArg: 3.563 ± 0.044	3.027ThrSer: 3.027 ± 0.042	3.806ThrThr: 3.806 ± 0.063	6.047ThrVal: 6.047 ± 0.057	0.845ThrTrp: 0.845 ± 0.023	1.25ThrTyr: 1.25 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	11.699ValAla: 11.699 ± 0.109	0.717ValCys: 0.717 ± 0.024	5.806ValAsp: 5.806 ± 0.062	4.784ValGlu: 4.784 ± 0.054	2.611ValPhe: 2.611 ± 0.048	7.118ValGly: 7.118 ± 0.077	1.769ValHis: 1.769 ± 0.036	3.957ValIle: 3.957 ± 0.047	1.606ValLys: 1.606 ± 0.039	9.401ValLeu: 9.401 ± 0.094	1.524ValMet: 1.524 ± 0.031	2.009ValAsn: 2.009 ± 0.033	4.748ValPro: 4.748 ± 0.054	2.206ValGln: 2.206 ± 0.037	5.858ValArg: 5.858 ± 0.069	4.525ValSer: 4.525 ± 0.058	5.356ValThr: 5.356 ± 0.064	8.373ValVal: 8.373 ± 0.083	1.033ValTrp: 1.033 ± 0.026	1.57ValTyr: 1.57 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.551TrpAla: 1.551 ± 0.034	0.155TrpCys: 0.155 ± 0.01	0.783TrpAsp: 0.783 ± 0.023	0.65TrpGlu: 0.65 ± 0.021	0.512TrpPhe: 0.512 ± 0.019	1.012TrpGly: 1.012 ± 0.027	0.369TrpHis: 0.369 ± 0.015	0.613TrpIle: 0.613 ± 0.022	0.307TrpLys: 0.307 ± 0.015	1.69TrpLeu: 1.69 ± 0.034	0.322TrpMet: 0.322 ± 0.013	0.395TrpAsn: 0.395 ± 0.016	0.811TrpPro: 0.811 ± 0.023	0.607TrpGln: 0.607 ± 0.022	1.263TrpArg: 1.263 ± 0.025	0.938TrpSer: 0.938 ± 0.021	0.916TrpThr: 0.916 ± 0.024	1.101TrpVal: 1.101 ± 0.026	0.332TrpTrp: 0.332 ± 0.014	0.314TrpTyr: 0.314 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.407TyrAla: 2.407 ± 0.037	0.233TyrCys: 0.233 ± 0.011	1.416TyrAsp: 1.416 ± 0.03	1.07TyrGlu: 1.07 ± 0.024	0.792TyrPhe: 0.792 ± 0.027	2.057TyrGly: 2.057 ± 0.037	0.457TyrHis: 0.457 ± 0.015	0.676TyrIle: 0.676 ± 0.02	0.356TyrLys: 0.356 ± 0.015	2.393TyrLeu: 2.393 ± 0.043	0.304TyrMet: 0.304 ± 0.013	0.489TyrAsn: 0.489 ± 0.018	1.256TyrPro: 1.256 ± 0.026	0.679TyrGln: 0.679 ± 0.021	1.851TyrArg: 1.851 ± 0.039	1.107TyrSer: 1.107 ± 0.024	1.186TyrThr: 1.186 ± 0.029	1.626TyrVal: 1.626 ± 0.032	0.351TyrTrp: 0.351 ± 0.015	0.513TyrTyr: 0.513 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5110 proteins (1670072 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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