Amino acid dipepetide frequency for Colletotrichum tofieldiae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.51AlaAla: 10.51 ± 0.072	1.134AlaCys: 1.134 ± 0.016	4.597AlaAsp: 4.597 ± 0.029	5.327AlaGlu: 5.327 ± 0.041	3.304AlaPhe: 3.304 ± 0.028	6.368AlaGly: 6.368 ± 0.041	1.794AlaHis: 1.794 ± 0.016	4.321AlaIle: 4.321 ± 0.032	4.264AlaLys: 4.264 ± 0.032	7.949AlaLeu: 7.949 ± 0.046	2.079AlaMet: 2.079 ± 0.018	3.135AlaAsn: 3.135 ± 0.024	5.189AlaPro: 5.189 ± 0.047	3.421AlaGln: 3.421 ± 0.03	5.027AlaArg: 5.027 ± 0.034	7.606AlaSer: 7.606 ± 0.039	5.644AlaThr: 5.644 ± 0.043	5.955AlaVal: 5.955 ± 0.039	1.322AlaTrp: 1.322 ± 0.018	2.244AlaTyr: 2.244 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.962CysAla: 0.962 ± 0.015	0.252CysCys: 0.252 ± 0.008	0.681CysAsp: 0.681 ± 0.012	0.573CysGlu: 0.573 ± 0.011	0.546CysPhe: 0.546 ± 0.01	0.983CysGly: 0.983 ± 0.015	0.325CysHis: 0.325 ± 0.008	0.691CysIle: 0.691 ± 0.011	0.522CysLys: 0.522 ± 0.011	1.219CysLeu: 1.219 ± 0.017	0.258CysMet: 0.258 ± 0.007	0.46CysAsn: 0.46 ± 0.009	0.66CysPro: 0.66 ± 0.012	0.449CysGln: 0.449 ± 0.008	0.763CysArg: 0.763 ± 0.01	0.937CysSer: 0.937 ± 0.013	0.697CysThr: 0.697 ± 0.012	0.815CysVal: 0.815 ± 0.011	0.215CysTrp: 0.215 ± 0.006	0.339CysTyr: 0.339 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.005AspAla: 5.005 ± 0.031	0.648AspCys: 0.648 ± 0.011	4.33AspAsp: 4.33 ± 0.045	4.38AspGlu: 4.38 ± 0.041	2.282AspPhe: 2.282 ± 0.021	4.291AspGly: 4.291 ± 0.027	1.198AspHis: 1.198 ± 0.014	2.889AspIle: 2.889 ± 0.025	2.428AspLys: 2.428 ± 0.021	4.935AspLeu: 4.935 ± 0.029	1.279AspMet: 1.279 ± 0.014	1.885AspAsn: 1.885 ± 0.018	3.288AspPro: 3.288 ± 0.025	1.804AspGln: 1.804 ± 0.02	3.014AspArg: 3.014 ± 0.027	3.909AspSer: 3.909 ± 0.034	2.851AspThr: 2.851 ± 0.02	3.824AspVal: 3.824 ± 0.026	0.942AspTrp: 0.942 ± 0.012	1.546AspTyr: 1.546 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.653GluAla: 5.653 ± 0.039	0.589GluCys: 0.589 ± 0.011	4.063GluAsp: 4.063 ± 0.033	5.133GluGlu: 5.133 ± 0.054	1.895GluPhe: 1.895 ± 0.021	3.752GluGly: 3.752 ± 0.032	1.35GluHis: 1.35 ± 0.014	2.788GluIle: 2.788 ± 0.023	3.592GluLys: 3.592 ± 0.031	4.958GluLeu: 4.958 ± 0.036	1.403GluMet: 1.403 ± 0.016	2.185GluAsn: 2.185 ± 0.019	2.879GluPro: 2.879 ± 0.043	2.271GluGln: 2.271 ± 0.023	3.739GluArg: 3.739 ± 0.034	4.015GluSer: 4.015 ± 0.033	3.538GluThr: 3.538 ± 0.028	3.629GluVal: 3.629 ± 0.029	0.88GluTrp: 0.88 ± 0.011	1.57GluTyr: 1.57 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.198PheAla: 3.198 ± 0.027	0.568PheCys: 0.568 ± 0.011	2.325PheAsp: 2.325 ± 0.021	2.12PheGlu: 2.12 ± 0.018	1.702PhePhe: 1.702 ± 0.02	3.015PheGly: 3.015 ± 0.028	0.893PheHis: 0.893 ± 0.012	1.775PheIle: 1.775 ± 0.02	1.512PheLys: 1.512 ± 0.017	3.446PheLeu: 3.446 ± 0.035	0.786PheMet: 0.786 ± 0.011	1.495PheAsn: 1.495 ± 0.017	1.964PhePro: 1.964 ± 0.019	1.364PheGln: 1.364 ± 0.015	1.948PheArg: 1.948 ± 0.02	2.971PheSer: 2.971 ± 0.023	2.199PheThr: 2.199 ± 0.021	2.522PheVal: 2.522 ± 0.022	0.684PheTrp: 0.684 ± 0.011	1.114PheTyr: 1.114 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.874GlyAla: 5.874 ± 0.04	0.925GlyCys: 0.925 ± 0.015	3.748GlyAsp: 3.748 ± 0.029	3.6GlyGlu: 3.6 ± 0.024	2.965GlyPhe: 2.965 ± 0.023	6.348GlyGly: 6.348 ± 0.066	1.766GlyHis: 1.766 ± 0.018	3.562GlyIle: 3.562 ± 0.028	3.466GlyLys: 3.466 ± 0.03	6.259GlyLeu: 6.259 ± 0.037	1.618GlyMet: 1.618 ± 0.019	2.701GlyAsn: 2.701 ± 0.024	3.531GlyPro: 3.531 ± 0.024	2.613GlyGln: 2.613 ± 0.022	4.254GlyArg: 4.254 ± 0.035	5.784GlySer: 5.784 ± 0.034	4.222GlyThr: 4.222 ± 0.053	4.625GlyVal: 4.625 ± 0.034	1.246GlyTrp: 1.246 ± 0.018	2.137GlyTyr: 2.137 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.863HisAla: 1.863 ± 0.02	0.328HisCys: 0.328 ± 0.008	1.295HisAsp: 1.295 ± 0.015	1.269HisGlu: 1.269 ± 0.014	0.918HisPhe: 0.918 ± 0.012	1.741HisGly: 1.741 ± 0.017	0.87HisHis: 0.87 ± 0.015	1.12HisIle: 1.12 ± 0.013	0.893HisLys: 0.893 ± 0.012	2.196HisLeu: 2.196 ± 0.023	0.502HisMet: 0.502 ± 0.009	0.849HisAsn: 0.849 ± 0.012	1.648HisPro: 1.648 ± 0.019	0.999HisGln: 0.999 ± 0.016	1.514HisArg: 1.514 ± 0.018	1.713HisSer: 1.713 ± 0.02	1.22HisThr: 1.22 ± 0.014	1.457HisVal: 1.457 ± 0.017	0.361HisTrp: 0.361 ± 0.008	0.684HisTyr: 0.684 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.207IleAla: 4.207 ± 0.028	0.703IleCys: 0.703 ± 0.012	2.746IleAsp: 2.746 ± 0.02	2.698IleGlu: 2.698 ± 0.024	1.916IlePhe: 1.916 ± 0.021	3.205IleGly: 3.205 ± 0.03	1.134IleHis: 1.134 ± 0.016	2.418IleIle: 2.418 ± 0.026	2.129IleLys: 2.129 ± 0.022	4.314IleLeu: 4.314 ± 0.033	1.022IleMet: 1.022 ± 0.014	1.742IleAsn: 1.742 ± 0.019	2.934IlePro: 2.934 ± 0.027	1.784IleGln: 1.784 ± 0.023	2.663IleArg: 2.663 ± 0.02	3.578IleSer: 3.578 ± 0.025	2.809IleThr: 2.809 ± 0.028	3.196IleVal: 3.196 ± 0.029	0.734IleTrp: 0.734 ± 0.013	1.322IleTyr: 1.322 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.444LysAla: 4.444 ± 0.033	0.495LysCys: 0.495 ± 0.011	2.769LysAsp: 2.769 ± 0.023	3.252LysGlu: 3.252 ± 0.032	1.425LysPhe: 1.425 ± 0.017	3.028LysGly: 3.028 ± 0.025	1.104LysHis: 1.104 ± 0.016	2.133LysIle: 2.133 ± 0.02	3.302LysLys: 3.302 ± 0.046	4.019LysLeu: 4.019 ± 0.03	1.025LysMet: 1.025 ± 0.012	1.732LysAsn: 1.732 ± 0.017	2.756LysPro: 2.756 ± 0.023	1.767LysGln: 1.767 ± 0.019	3.22LysArg: 3.22 ± 0.026	3.385LysSer: 3.385 ± 0.029	2.943LysThr: 2.943 ± 0.026	2.827LysVal: 2.827 ± 0.024	0.695LysTrp: 0.695 ± 0.012	1.322LysTyr: 1.322 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.209LeuAla: 8.209 ± 0.047	1.193LeuCys: 1.193 ± 0.014	5.046LeuAsp: 5.046 ± 0.035	5.3LeuGlu: 5.3 ± 0.034	3.286LeuPhe: 3.286 ± 0.03	6.161LeuGly: 6.161 ± 0.042	2.157LeuHis: 2.157 ± 0.019	3.72LeuIle: 3.72 ± 0.031	4.01LeuLys: 4.01 ± 0.03	8.177LeuLeu: 8.177 ± 0.057	1.759LeuMet: 1.759 ± 0.018	3.053LeuAsn: 3.053 ± 0.024	5.493LeuPro: 5.493 ± 0.036	3.642LeuGln: 3.642 ± 0.028	5.635LeuArg: 5.635 ± 0.031	6.977LeuSer: 6.977 ± 0.038	4.834LeuThr: 4.834 ± 0.027	5.611LeuVal: 5.611 ± 0.042	1.258LeuTrp: 1.258 ± 0.017	2.263LeuTyr: 2.263 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.4MetAla: 2.4 ± 0.018	0.234MetCys: 0.234 ± 0.006	1.214MetAsp: 1.214 ± 0.017	1.215MetGlu: 1.215 ± 0.017	0.765MetPhe: 0.765 ± 0.015	1.493MetGly: 1.493 ± 0.018	0.457MetHis: 0.457 ± 0.009	0.946MetIle: 0.946 ± 0.013	1.0MetLys: 1.0 ± 0.014	1.854MetLeu: 1.854 ± 0.019	0.597MetMet: 0.597 ± 0.01	0.781MetAsn: 0.781 ± 0.012	1.322MetPro: 1.322 ± 0.014	0.814MetGln: 0.814 ± 0.013	1.275MetArg: 1.275 ± 0.014	1.84MetSer: 1.84 ± 0.017	1.333MetThr: 1.333 ± 0.017	1.35MetVal: 1.35 ± 0.013	0.277MetTrp: 0.277 ± 0.007	0.526MetTyr: 0.526 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.207AsnAla: 3.207 ± 0.024	0.453AsnCys: 0.453 ± 0.01	1.949AsnAsp: 1.949 ± 0.018	1.941AsnGlu: 1.941 ± 0.02	1.413AsnPhe: 1.413 ± 0.016	3.139AsnGly: 3.139 ± 0.03	0.842AsnHis: 0.842 ± 0.011	1.973AsnIle: 1.973 ± 0.018	1.589AsnLys: 1.589 ± 0.017	3.199AsnLeu: 3.199 ± 0.023	0.859AsnMet: 0.859 ± 0.013	1.533AsnAsn: 1.533 ± 0.024	2.44AsnPro: 2.44 ± 0.026	1.317AsnGln: 1.317 ± 0.016	1.883AsnArg: 1.883 ± 0.018	2.658AsnSer: 2.658 ± 0.022	2.184AsnThr: 2.184 ± 0.019	2.329AsnVal: 2.329 ± 0.02	0.583AsnTrp: 0.583 ± 0.01	1.045AsnTyr: 1.045 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.774ProAla: 5.774 ± 0.049	0.522ProCys: 0.522 ± 0.011	3.222ProAsp: 3.222 ± 0.025	3.91ProGlu: 3.91 ± 0.035	2.077ProPhe: 2.077 ± 0.021	4.175ProGly: 4.175 ± 0.033	1.29ProHis: 1.29 ± 0.016	2.465ProIle: 2.465 ± 0.019	2.71ProLys: 2.71 ± 0.028	4.677ProLeu: 4.677 ± 0.029	1.099ProMet: 1.099 ± 0.016	2.206ProAsn: 2.206 ± 0.022	5.259ProPro: 5.259 ± 0.068	2.463ProGln: 2.463 ± 0.03	3.517ProArg: 3.517 ± 0.028	5.84ProSer: 5.84 ± 0.049	4.106ProThr: 4.106 ± 0.04	3.721ProVal: 3.721 ± 0.032	0.793ProTrp: 0.793 ± 0.014	1.469ProTyr: 1.469 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.515GlnAla: 3.515 ± 0.027	0.46GlnCys: 0.46 ± 0.009	1.985GlnAsp: 1.985 ± 0.02	2.245GlnGlu: 2.245 ± 0.022	1.226GlnPhe: 1.226 ± 0.014	2.433GlnGly: 2.433 ± 0.023	1.094GlnHis: 1.094 ± 0.015	1.767GlnIle: 1.767 ± 0.019	1.866GlnLys: 1.866 ± 0.017	3.326GlnLeu: 3.326 ± 0.03	0.895GlnMet: 0.895 ± 0.012	1.459GlnAsn: 1.459 ± 0.017	2.586GlnPro: 2.586 ± 0.032	2.583GlnGln: 2.583 ± 0.05	2.573GlnArg: 2.573 ± 0.021	2.897GlnSer: 2.897 ± 0.03	2.335GlnThr: 2.335 ± 0.029	2.15GlnVal: 2.15 ± 0.02	0.577GlnTrp: 0.577 ± 0.009	1.124GlnTyr: 1.124 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.745ArgAla: 4.745 ± 0.029	0.726ArgCys: 0.726 ± 0.011	3.425ArgAsp: 3.425 ± 0.031	3.647ArgGlu: 3.647 ± 0.028	2.117ArgPhe: 2.117 ± 0.018	3.802ArgGly: 3.802 ± 0.029	1.578ArgHis: 1.578 ± 0.019	2.734ArgIle: 2.734 ± 0.023	3.306ArgLys: 3.306 ± 0.029	5.393ArgLeu: 5.393 ± 0.035	1.265ArgMet: 1.265 ± 0.012	2.219ArgAsn: 2.219 ± 0.02	3.66ArgPro: 3.66 ± 0.03	2.614ArgGln: 2.614 ± 0.025	5.086ArgArg: 5.086 ± 0.049	4.602ArgSer: 4.602 ± 0.043	3.262ArgThr: 3.262 ± 0.025	3.422ArgVal: 3.422 ± 0.027	0.959ArgTrp: 0.959 ± 0.013	1.6ArgTyr: 1.6 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.828SerAla: 6.828 ± 0.039	0.882SerCys: 0.882 ± 0.013	4.082SerAsp: 4.082 ± 0.029	3.902SerGlu: 3.902 ± 0.032	3.061SerPhe: 3.061 ± 0.025	5.641SerGly: 5.641 ± 0.041	1.853SerHis: 1.853 ± 0.018	3.783SerIle: 3.783 ± 0.033	3.574SerLys: 3.574 ± 0.031	6.965SerLeu: 6.965 ± 0.039	1.681SerMet: 1.681 ± 0.016	2.871SerAsn: 2.871 ± 0.025	5.359SerPro: 5.359 ± 0.051	3.146SerGln: 3.146 ± 0.032	4.863SerArg: 4.863 ± 0.041	8.189SerSer: 8.189 ± 0.065	5.362SerThr: 5.362 ± 0.049	4.648SerVal: 4.648 ± 0.033	1.173SerTrp: 1.173 ± 0.014	2.035SerTyr: 2.035 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.605ThrAla: 5.605 ± 0.039	0.763ThrCys: 0.763 ± 0.013	2.878ThrAsp: 2.878 ± 0.022	3.126ThrGlu: 3.126 ± 0.027	2.272ThrPhe: 2.272 ± 0.021	4.314ThrGly: 4.314 ± 0.048	1.244ThrHis: 1.244 ± 0.015	3.076ThrIle: 3.076 ± 0.032	2.643ThrLys: 2.643 ± 0.024	5.172ThrLeu: 5.172 ± 0.037	1.266ThrMet: 1.266 ± 0.014	2.162ThrAsn: 2.162 ± 0.02	4.424ThrPro: 4.424 ± 0.038	2.088ThrGln: 2.088 ± 0.018	3.126ThrArg: 3.126 ± 0.024	5.222ThrSer: 5.222 ± 0.052	4.504ThrThr: 4.504 ± 0.064	3.954ThrVal: 3.954 ± 0.052	0.921ThrTrp: 0.921 ± 0.012	1.645ThrTyr: 1.645 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.769ValAla: 5.769 ± 0.035	0.852ValCys: 0.852 ± 0.013	3.78ValAsp: 3.78 ± 0.024	3.879ValGlu: 3.879 ± 0.03	2.649ValPhe: 2.649 ± 0.023	4.246ValGly: 4.246 ± 0.032	1.354ValHis: 1.354 ± 0.015	3.017ValIle: 3.017 ± 0.027	2.938ValLys: 2.938 ± 0.024	5.768ValLeu: 5.768 ± 0.04	1.328ValMet: 1.328 ± 0.014	2.264ValAsn: 2.264 ± 0.021	3.776ValPro: 3.776 ± 0.03	2.323ValGln: 2.323 ± 0.02	3.506ValArg: 3.506 ± 0.028	4.722ValSer: 4.722 ± 0.03	3.778ValThr: 3.778 ± 0.041	4.649ValVal: 4.649 ± 0.037	0.96ValTrp: 0.96 ± 0.015	1.765ValTyr: 1.765 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.251TrpAla: 1.251 ± 0.015	0.205TrpCys: 0.205 ± 0.007	0.944TrpAsp: 0.944 ± 0.014	0.866TrpGlu: 0.866 ± 0.013	0.587TrpPhe: 0.587 ± 0.01	1.003TrpGly: 1.003 ± 0.014	0.392TrpHis: 0.392 ± 0.008	0.764TrpIle: 0.764 ± 0.011	0.826TrpLys: 0.826 ± 0.013	1.393TrpLeu: 1.393 ± 0.017	0.378TrpMet: 0.378 ± 0.008	0.679TrpAsn: 0.679 ± 0.012	0.673TrpPro: 0.673 ± 0.012	0.603TrpGln: 0.603 ± 0.009	0.975TrpArg: 0.975 ± 0.014	1.097TrpSer: 1.097 ± 0.015	0.983TrpThr: 0.983 ± 0.015	0.964TrpVal: 0.964 ± 0.014	0.309TrpTrp: 0.309 ± 0.008	0.47TrpTyr: 0.47 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.17TyrAla: 2.17 ± 0.02	0.417TyrCys: 0.417 ± 0.009	1.651TyrAsp: 1.651 ± 0.019	1.498TyrGlu: 1.498 ± 0.016	1.198TyrPhe: 1.198 ± 0.014	2.106TyrGly: 2.106 ± 0.021	0.744TyrHis: 0.744 ± 0.012	1.312TyrIle: 1.312 ± 0.016	1.072TyrLys: 1.072 ± 0.014	2.564TyrLeu: 2.564 ± 0.024	0.593TyrMet: 0.593 ± 0.01	1.127TyrAsn: 1.127 ± 0.015	1.451TyrPro: 1.451 ± 0.015	1.032TyrGln: 1.032 ± 0.013	1.578TyrArg: 1.578 ± 0.017	1.956TyrSer: 1.956 ± 0.023	1.602TyrThr: 1.602 ± 0.021	1.678TyrVal: 1.678 ± 0.019	0.472TyrTrp: 0.472 ± 0.01	0.898TyrTyr: 0.898 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12499 proteins (6353999 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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