Amino acid dipepetide frequency for Adonis mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.714AlaAla: 5.714 ± 2.509
1.27AlaCys: 1.27 ± 0.517
1.905AlaAsp: 1.905 ± 1.34
5.714AlaGlu: 5.714 ± 0.89
3.175AlaPhe: 3.175 ± 1.339
5.714AlaGly: 5.714 ± 0.942
3.175AlaHis: 3.175 ± 1.258
4.444AlaIle: 4.444 ± 0.887
4.444AlaLys: 4.444 ± 1.983
6.984AlaLeu: 6.984 ± 1.533
2.54AlaMet: 2.54 ± 1.273
3.81AlaAsn: 3.81 ± 0.99
2.54AlaPro: 2.54 ± 1.525
1.905AlaGln: 1.905 ± 1.036
3.175AlaArg: 3.175 ± 1.529
6.349AlaSer: 6.349 ± 1.427
3.175AlaThr: 3.175 ± 1.269
6.349AlaVal: 6.349 ± 2.516
3.175AlaTrp: 3.175 ± 1.269
1.905AlaTyr: 1.905 ± 0.687
0.0AlaXaa: 0.0 ± 0.0
Cys
1.27CysAla: 1.27 ± 0.637
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.27CysGlu: 1.27 ± 0.763
0.635CysPhe: 0.635 ± 0.381
1.905CysGly: 1.905 ± 1.006
0.0CysHis: 0.0 ± 0.0
1.905CysIle: 1.905 ± 0.864
3.175CysLys: 3.175 ± 1.595
1.27CysLeu: 1.27 ± 0.763
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.635CysPro: 0.635 ± 0.381
0.635CysGln: 0.635 ± 0.381
0.635CysArg: 0.635 ± 0.381
1.27CysSer: 1.27 ± 1.222
0.0CysThr: 0.0 ± 0.0
3.175CysVal: 3.175 ± 0.945
0.0CysTrp: 0.0 ± 0.0
1.27CysTyr: 1.27 ± 0.763
0.0CysXaa: 0.0 ± 0.0
Asp
3.175AspAla: 3.175 ± 1.339
1.27AspCys: 1.27 ± 0.763
2.54AspAsp: 2.54 ± 1.033
1.905AspGlu: 1.905 ± 1.072
2.54AspPhe: 2.54 ± 1.488
3.81AspGly: 3.81 ± 2.072
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
3.81AspLys: 3.81 ± 1.457
3.175AspLeu: 3.175 ± 1.216
2.54AspMet: 2.54 ± 0.911
0.0AspAsn: 0.0 ± 0.0
2.54AspPro: 2.54 ± 1.033
3.175AspGln: 3.175 ± 1.216
0.635AspArg: 0.635 ± 1.473
3.175AspSer: 3.175 ± 2.766
0.0AspThr: 0.0 ± 0.0
1.27AspVal: 1.27 ± 0.517
0.635AspTrp: 0.635 ± 0.585
1.27AspTyr: 1.27 ± 0.517
0.0AspXaa: 0.0 ± 0.0
Glu
8.254GluAla: 8.254 ± 1.999
0.0GluCys: 0.0 ± 0.0
3.175GluAsp: 3.175 ± 1.108
8.254GluGlu: 8.254 ± 1.988
3.175GluPhe: 3.175 ± 1.195
4.444GluGly: 4.444 ± 0.887
1.905GluHis: 1.905 ± 1.144
1.27GluIle: 1.27 ± 0.763
3.175GluLys: 3.175 ± 0.815
6.984GluLeu: 6.984 ± 0.946
0.635GluMet: 0.635 ± 0.943
1.27GluAsn: 1.27 ± 0.517
0.0GluPro: 0.0 ± 0.0
1.27GluGln: 1.27 ± 0.763
5.714GluArg: 5.714 ± 1.824
5.714GluSer: 5.714 ± 2.168
3.81GluThr: 3.81 ± 1.265
7.619GluVal: 7.619 ± 1.635
0.635GluTrp: 0.635 ± 0.585
2.54GluTyr: 2.54 ± 0.475
0.0GluXaa: 0.0 ± 0.0
Phe
1.905PheAla: 1.905 ± 0.687
1.27PheCys: 1.27 ± 0.813
3.81PheAsp: 3.81 ± 1.342
5.714PheGlu: 5.714 ± 1.159
0.635PhePhe: 0.635 ± 1.162
3.175PheGly: 3.175 ± 0.602
1.27PheHis: 1.27 ± 1.108
3.175PheIle: 3.175 ± 0.602
1.27PheLys: 1.27 ± 0.763
4.444PheLeu: 4.444 ± 1.699
0.635PheMet: 0.635 ± 1.316
3.81PheAsn: 3.81 ± 1.265
1.27PhePro: 1.27 ± 1.222
1.27PheGln: 1.27 ± 0.517
1.27PheArg: 1.27 ± 0.517
1.27PheSer: 1.27 ± 1.373
3.81PheThr: 3.81 ± 1.91
2.54PheVal: 2.54 ± 2.176
0.0PheTrp: 0.0 ± 0.0
2.54PheTyr: 2.54 ± 0.994
0.0PheXaa: 0.0 ± 0.0
Gly
2.54GlyAla: 2.54 ± 0.994
1.27GlyCys: 1.27 ± 0.763
5.079GlyAsp: 5.079 ± 1.587
3.81GlyGlu: 3.81 ± 1.914
5.079GlyPhe: 5.079 ± 1.133
6.984GlyGly: 6.984 ± 1.08
0.0GlyHis: 0.0 ± 0.0
1.905GlyIle: 1.905 ± 0.687
5.714GlyLys: 5.714 ± 1.806
7.619GlyLeu: 7.619 ± 1.788
3.175GlyMet: 3.175 ± 1.216
3.175GlyAsn: 3.175 ± 2.601
1.905GlyPro: 1.905 ± 1.036
1.27GlyGln: 1.27 ± 0.517
4.444GlyArg: 4.444 ± 0.887
7.619GlySer: 7.619 ± 1.287
3.81GlyThr: 3.81 ± 1.064
3.81GlyVal: 3.81 ± 1.303
1.905GlyTrp: 1.905 ± 1.036
3.175GlyTyr: 3.175 ± 1.163
0.0GlyXaa: 0.0 ± 0.0
His
1.905HisAla: 1.905 ± 0.694
0.0HisCys: 0.0 ± 0.0
1.27HisAsp: 1.27 ± 1.615
2.54HisGlu: 2.54 ± 1.44
1.27HisPhe: 1.27 ± 0.637
1.27HisGly: 1.27 ± 1.108
0.0HisHis: 0.0 ± 0.0
1.905HisIle: 1.905 ± 1.294
0.0HisLys: 0.0 ± 0.0
1.27HisLeu: 1.27 ± 0.763
0.0HisMet: 0.0 ± 0.0
1.27HisAsn: 1.27 ± 0.763
2.54HisPro: 2.54 ± 0.475
0.0HisGln: 0.0 ± 0.0
1.27HisArg: 1.27 ± 1.108
4.444HisSer: 4.444 ± 0.986
1.905HisThr: 1.905 ± 0.687
0.635HisVal: 0.635 ± 0.381
0.635HisTrp: 0.635 ± 0.381
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.349IleAla: 6.349 ± 1.047
1.27IleCys: 1.27 ± 0.763
0.635IleAsp: 0.635 ± 0.381
2.54IleGlu: 2.54 ± 0.911
0.635IlePhe: 0.635 ± 0.776
2.54IleGly: 2.54 ± 0.905
0.635IleHis: 0.635 ± 0.381
1.905IleIle: 1.905 ± 0.939
1.27IleLys: 1.27 ± 1.108
1.905IleLeu: 1.905 ± 1.377
0.635IleMet: 0.635 ± 0.381
4.444IleAsn: 4.444 ± 1.102
1.27IlePro: 1.27 ± 0.517
3.175IleGln: 3.175 ± 1.216
4.444IleArg: 4.444 ± 1.574
4.444IleSer: 4.444 ± 0.986
3.81IleThr: 3.81 ± 2.296
2.54IleVal: 2.54 ± 0.905
0.635IleTrp: 0.635 ± 0.381
0.635IleTyr: 0.635 ± 0.381
0.0IleXaa: 0.0 ± 0.0
Lys
5.079LysAla: 5.079 ± 1.587
1.27LysCys: 1.27 ± 0.637
2.54LysAsp: 2.54 ± 1.43
6.349LysGlu: 6.349 ± 2.037
6.349LysPhe: 6.349 ± 1.427
3.81LysGly: 3.81 ± 0.761
3.175LysHis: 3.175 ± 1.865
2.54LysIle: 2.54 ± 1.046
1.905LysLys: 1.905 ± 1.036
5.714LysLeu: 5.714 ± 2.828
1.905LysMet: 1.905 ± 0.92
3.175LysAsn: 3.175 ± 1.269
3.81LysPro: 3.81 ± 2.613
1.905LysGln: 1.905 ± 1.411
2.54LysArg: 2.54 ± 0.475
1.905LysSer: 1.905 ± 0.616
1.905LysThr: 1.905 ± 1.144
1.905LysVal: 1.905 ± 1.036
0.0LysTrp: 0.0 ± 0.0
2.54LysTyr: 2.54 ± 0.475
0.635LysXaa: 0.635 ± 1.162
Leu
4.444LeuAla: 4.444 ± 0.887
1.27LeuCys: 1.27 ± 0.637
1.27LeuAsp: 1.27 ± 0.517
5.079LeuGlu: 5.079 ± 2.274
2.54LeuPhe: 2.54 ± 0.475
3.81LeuGly: 3.81 ± 1.389
0.635LeuHis: 0.635 ± 0.776
3.81LeuIle: 3.81 ± 0.889
6.349LeuLys: 6.349 ± 1.669
7.619LeuLeu: 7.619 ± 3.796
2.54LeuMet: 2.54 ± 0.905
3.81LeuAsn: 3.81 ± 1.948
2.54LeuPro: 2.54 ± 2.32
1.27LeuGln: 1.27 ± 0.517
5.079LeuArg: 5.079 ± 0.971
8.254LeuSer: 8.254 ± 1.374
8.889LeuThr: 8.889 ± 2.017
7.619LeuVal: 7.619 ± 1.747
1.27LeuTrp: 1.27 ± 1.373
0.635LeuTyr: 0.635 ± 0.381
0.0LeuXaa: 0.0 ± 0.0
Met
5.079MetAla: 5.079 ± 1.357
0.635MetCys: 0.635 ± 0.585
0.0MetAsp: 0.0 ± 0.0
1.905MetGlu: 1.905 ± 0.616
0.635MetPhe: 0.635 ± 0.381
2.54MetGly: 2.54 ± 1.273
0.0MetHis: 0.0 ± 0.0
1.27MetIle: 1.27 ± 0.763
1.27MetLys: 1.27 ± 0.763
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.635MetAsn: 0.635 ± 0.381
0.635MetPro: 0.635 ± 0.776
0.635MetGln: 0.635 ± 0.381
3.175MetArg: 3.175 ± 1.404
4.444MetSer: 4.444 ± 0.887
0.635MetThr: 0.635 ± 0.585
1.27MetVal: 1.27 ± 1.108
0.0MetTrp: 0.0 ± 0.0
0.635MetTyr: 0.635 ± 0.585
0.0MetXaa: 0.0 ± 0.0
Asn
1.905AsnAla: 1.905 ± 1.144
1.905AsnCys: 1.905 ± 1.006
1.27AsnAsp: 1.27 ± 1.17
0.635AsnGlu: 0.635 ± 0.381
1.27AsnPhe: 1.27 ± 1.506
4.444AsnGly: 4.444 ± 1.102
3.81AsnHis: 3.81 ± 1.303
1.27AsnIle: 1.27 ± 1.356
0.635AsnLys: 0.635 ± 0.585
3.81AsnLeu: 3.81 ± 1.274
0.0AsnMet: 0.0 ± 0.0
3.175AsnAsn: 3.175 ± 1.297
3.175AsnPro: 3.175 ± 0.815
1.905AsnGln: 1.905 ± 1.377
2.54AsnArg: 2.54 ± 1.488
5.079AsnSer: 5.079 ± 1.939
1.905AsnThr: 1.905 ± 1.006
1.905AsnVal: 1.905 ± 1.756
0.635AsnTrp: 0.635 ± 1.473
1.27AsnTyr: 1.27 ± 0.637
0.0AsnXaa: 0.0 ± 0.0
Pro
3.175ProAla: 3.175 ± 0.602
0.635ProCys: 0.635 ± 1.162
2.54ProAsp: 2.54 ± 0.911
3.175ProGlu: 3.175 ± 1.622
0.0ProPhe: 0.0 ± 0.0
1.27ProGly: 1.27 ± 0.517
0.635ProHis: 0.635 ± 1.162
0.0ProIle: 0.0 ± 0.0
5.079ProLys: 5.079 ± 0.971
1.905ProLeu: 1.905 ± 0.939
0.0ProMet: 0.0 ± 0.0
1.27ProAsn: 1.27 ± 0.517
2.54ProPro: 2.54 ± 1.558
1.905ProGln: 1.905 ± 1.072
3.81ProArg: 3.81 ± 1.364
4.444ProSer: 4.444 ± 1.633
2.54ProThr: 2.54 ± 1.601
4.444ProVal: 4.444 ± 1.66
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.27GlnAla: 1.27 ± 1.17
1.27GlnCys: 1.27 ± 0.763
0.635GlnAsp: 0.635 ± 0.585
1.27GlnGlu: 1.27 ± 0.763
1.27GlnPhe: 1.27 ± 1.108
0.635GlnGly: 0.635 ± 0.381
2.54GlnHis: 2.54 ± 1.286
2.54GlnIle: 2.54 ± 0.936
2.54GlnLys: 2.54 ± 0.475
3.175GlnLeu: 3.175 ± 0.815
3.175GlnMet: 3.175 ± 0.815
3.175GlnAsn: 3.175 ± 1.065
1.27GlnPro: 1.27 ± 0.763
1.905GlnGln: 1.905 ± 0.939
0.635GlnArg: 0.635 ± 1.162
0.635GlnSer: 0.635 ± 0.585
2.54GlnThr: 2.54 ± 2.341
3.175GlnVal: 3.175 ± 1.269
1.27GlnTrp: 1.27 ± 0.763
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.175ArgAla: 3.175 ± 1.578
1.27ArgCys: 1.27 ± 2.325
0.635ArgAsp: 0.635 ± 0.381
1.905ArgGlu: 1.905 ± 1.377
3.175ArgPhe: 3.175 ± 1.336
6.349ArgGly: 6.349 ± 1.128
1.27ArgHis: 1.27 ± 0.637
2.54ArgIle: 2.54 ± 0.911
4.444ArgLys: 4.444 ± 1.813
3.175ArgLeu: 3.175 ± 0.945
1.27ArgMet: 1.27 ± 0.763
1.27ArgAsn: 1.27 ± 0.517
1.27ArgPro: 1.27 ± 0.517
1.905ArgGln: 1.905 ± 0.616
6.984ArgArg: 6.984 ± 2.24
6.349ArgSer: 6.349 ± 2.411
0.635ArgThr: 0.635 ± 0.381
10.794ArgVal: 10.794 ± 2.082
0.0ArgTrp: 0.0 ± 0.0
3.81ArgTyr: 3.81 ± 0.889
0.0ArgXaa: 0.0 ± 0.0
Ser
7.619SerAla: 7.619 ± 1.31
1.27SerCys: 1.27 ± 0.763
6.349SerAsp: 6.349 ± 3.071
4.444SerGlu: 4.444 ± 1.204
3.175SerPhe: 3.175 ± 1.192
2.54SerGly: 2.54 ± 0.994
3.81SerHis: 3.81 ± 0.998
1.905SerIle: 1.905 ± 1.543
8.254SerLys: 8.254 ± 2.419
7.619SerLeu: 7.619 ± 1.523
3.175SerMet: 3.175 ± 0.602
2.54SerAsn: 2.54 ± 1.509
1.905SerPro: 1.905 ± 1.072
4.444SerGln: 4.444 ± 1.106
5.714SerArg: 5.714 ± 1.724
5.079SerSer: 5.079 ± 1.268
3.175SerThr: 3.175 ± 0.815
6.349SerVal: 6.349 ± 1.047
2.54SerTrp: 2.54 ± 1.019
0.635SerTyr: 0.635 ± 0.381
0.0SerXaa: 0.0 ± 0.0
Thr
3.175ThrAla: 3.175 ± 1.217
1.27ThrCys: 1.27 ± 0.637
0.635ThrAsp: 0.635 ± 0.585
3.81ThrGlu: 3.81 ± 0.998
1.905ThrPhe: 1.905 ± 0.687
5.714ThrGly: 5.714 ± 1.255
0.0ThrHis: 0.0 ± 0.0
5.714ThrIle: 5.714 ± 1.175
3.175ThrLys: 3.175 ± 1.397
4.444ThrLeu: 4.444 ± 1.106
0.635ThrMet: 0.635 ± 0.367
3.175ThrAsn: 3.175 ± 1.201
3.81ThrPro: 3.81 ± 1.086
0.635ThrGln: 0.635 ± 0.585
4.444ThrArg: 4.444 ± 0.887
1.905ThrSer: 1.905 ± 0.694
3.81ThrThr: 3.81 ± 2.072
3.81ThrVal: 3.81 ± 2.525
0.0ThrTrp: 0.0 ± 0.0
0.635ThrTyr: 0.635 ± 0.585
0.0ThrXaa: 0.0 ± 0.0
Val
8.889ValAla: 8.889 ± 3.007
1.905ValCys: 1.905 ± 0.616
2.54ValAsp: 2.54 ± 1.601
7.619ValGlu: 7.619 ± 1.557
5.714ValPhe: 5.714 ± 1.182
10.159ValGly: 10.159 ± 1.229
1.27ValHis: 1.27 ± 0.763
5.714ValIle: 5.714 ± 2.299
2.54ValLys: 2.54 ± 1.046
2.54ValLeu: 2.54 ± 1.019
1.905ValMet: 1.905 ± 1.034
0.635ValAsn: 0.635 ± 0.776
4.444ValPro: 4.444 ± 1.217
2.54ValGln: 2.54 ± 0.911
3.81ValArg: 3.81 ± 1.679
7.619ValSer: 7.619 ± 1.287
3.175ValThr: 3.175 ± 2.137
10.794ValVal: 10.794 ± 2.154
1.905ValTrp: 1.905 ± 1.072
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.27TrpAla: 1.27 ± 0.517
0.0TrpCys: 0.0 ± 0.0
0.635TrpAsp: 0.635 ± 0.381
1.27TrpGlu: 1.27 ± 0.637
2.54TrpPhe: 2.54 ± 1.325
1.905TrpGly: 1.905 ± 0.687
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.635TrpLys: 0.635 ± 1.162
1.27TrpLeu: 1.27 ± 0.813
0.0TrpMet: 0.0 ± 0.0
0.635TrpAsn: 0.635 ± 0.381
0.0TrpPro: 0.0 ± 0.0
0.635TrpGln: 0.635 ± 0.585
0.0TrpArg: 0.0 ± 0.0
1.27TrpSer: 1.27 ± 1.17
0.635TrpThr: 0.635 ± 1.473
1.27TrpVal: 1.27 ± 0.517
0.635TrpTrp: 0.635 ± 1.162
1.27TrpTyr: 1.27 ± 0.637
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.27TyrAla: 1.27 ± 1.17
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.635TyrGlu: 0.635 ± 0.381
0.0TyrPhe: 0.0 ± 0.0
1.27TyrGly: 1.27 ± 0.517
0.0TyrHis: 0.0 ± 0.0
1.905TyrIle: 1.905 ± 0.687
1.27TyrLys: 1.27 ± 0.517
3.81TyrLeu: 3.81 ± 1.555
0.0TyrMet: 0.0 ± 0.0
1.27TyrAsn: 1.27 ± 0.517
1.27TyrPro: 1.27 ± 0.637
2.54TyrGln: 2.54 ± 0.994
1.905TyrArg: 1.905 ± 0.687
1.27TyrSer: 1.27 ± 0.517
2.54TyrThr: 2.54 ± 1.033
3.81TyrVal: 3.81 ± 1.374
0.0TyrTrp: 0.0 ± 0.0
0.635TyrTyr: 0.635 ± 0.381
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.635XaaVal: 0.635 ± 1.162
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1576 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski