Amino acid dipepetide frequency for Natrialba asiatica (strain ATCC 700177 / DSM 12278 / JCM 9576 / FERM P-10747 / NBRC 102637 / 172P1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.024AlaAla: 13.024 ± 0.156	0.699AlaCys: 0.699 ± 0.028	9.928AlaAsp: 9.928 ± 0.109	8.523AlaGlu: 8.523 ± 0.101	3.844AlaPhe: 3.844 ± 0.059	9.15AlaGly: 9.15 ± 0.108	1.83AlaHis: 1.83 ± 0.041	5.586AlaIle: 5.586 ± 0.075	1.662AlaLys: 1.662 ± 0.039	9.813AlaLeu: 9.813 ± 0.107	2.031AlaMet: 2.031 ± 0.042	2.47AlaAsn: 2.47 ± 0.05	3.736AlaPro: 3.736 ± 0.062	2.256AlaGln: 2.256 ± 0.041	5.711AlaArg: 5.711 ± 0.067	5.488AlaSer: 5.488 ± 0.08	7.662AlaThr: 7.662 ± 0.101	9.81AlaVal: 9.81 ± 0.092	1.027AlaTrp: 1.027 ± 0.03	2.547AlaTyr: 2.547 ± 0.053	0.002AlaXaa: 0.002 ± 0.001
Cys	0.592CysAla: 0.592 ± 0.023	0.101CysCys: 0.101 ± 0.009	0.58CysAsp: 0.58 ± 0.023	0.615CysGlu: 0.615 ± 0.022	0.206CysPhe: 0.206 ± 0.013	0.828CysGly: 0.828 ± 0.032	0.189CysHis: 0.189 ± 0.012	0.283CysIle: 0.283 ± 0.014	0.134CysLys: 0.134 ± 0.012	0.603CysLeu: 0.603 ± 0.023	0.111CysMet: 0.111 ± 0.01	0.197CysAsn: 0.197 ± 0.012	0.501CysPro: 0.501 ± 0.023	0.193CysGln: 0.193 ± 0.013	0.494CysArg: 0.494 ± 0.023	0.475CysSer: 0.475 ± 0.02	0.465CysThr: 0.465 ± 0.022	0.475CysVal: 0.475 ± 0.02	0.093CysTrp: 0.093 ± 0.009	0.255CysTyr: 0.255 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	9.924AspAla: 9.924 ± 0.115	0.658AspCys: 0.658 ± 0.023	7.893AspAsp: 7.893 ± 0.104	9.079AspGlu: 9.079 ± 0.11	1.716AspPhe: 1.716 ± 0.038	8.206AspGly: 8.206 ± 0.097	1.868AspHis: 1.868 ± 0.04	3.42AspIle: 3.42 ± 0.056	0.881AspLys: 0.881 ± 0.033	6.516AspLeu: 6.516 ± 0.092	1.13AspMet: 1.13 ± 0.03	1.419AspAsn: 1.419 ± 0.035	4.722AspPro: 4.722 ± 0.07	1.908AspGln: 1.908 ± 0.041	6.836AspArg: 6.836 ± 0.102	4.185AspSer: 4.185 ± 0.065	4.638AspThr: 4.638 ± 0.079	6.777AspVal: 6.777 ± 0.091	1.063AspTrp: 1.063 ± 0.034	1.811AspTyr: 1.811 ± 0.047	0.001AspXaa: 0.001 ± 0.001
Glu	7.963GluAla: 7.963 ± 0.093	0.55GluCys: 0.55 ± 0.022	5.377GluAsp: 5.377 ± 0.091	5.853GluGlu: 5.853 ± 0.099	4.011GluPhe: 4.011 ± 0.057	4.988GluGly: 4.988 ± 0.076	2.053GluHis: 2.053 ± 0.04	4.146GluIle: 4.146 ± 0.068	1.685GluLys: 1.685 ± 0.048	8.885GluLeu: 8.885 ± 0.088	1.792GluMet: 1.792 ± 0.04	2.648GluAsn: 2.648 ± 0.051	4.193GluPro: 4.193 ± 0.07	2.97GluGln: 2.97 ± 0.057	7.427GluArg: 7.427 ± 0.094	5.636GluSer: 5.636 ± 0.074	8.183GluThr: 8.183 ± 0.12	4.679GluVal: 4.679 ± 0.071	1.134GluTrp: 1.134 ± 0.029	2.522GluTyr: 2.522 ± 0.046	0.004GluXaa: 0.004 ± 0.002
Phe	3.583PheAla: 3.583 ± 0.056	0.289PheCys: 0.289 ± 0.017	3.234PheAsp: 3.234 ± 0.054	3.153PheGlu: 3.153 ± 0.055	1.016PhePhe: 1.016 ± 0.032	3.147PheGly: 3.147 ± 0.063	0.643PheHis: 0.643 ± 0.021	1.268PheIle: 1.268 ± 0.04	0.423PheLys: 0.423 ± 0.021	2.788PheLeu: 2.788 ± 0.057	0.513PheMet: 0.513 ± 0.024	0.742PheAsn: 0.742 ± 0.029	1.344PhePro: 1.344 ± 0.034	0.818PheGln: 0.818 ± 0.027	1.742PheArg: 1.742 ± 0.045	1.9PheSer: 1.9 ± 0.045	2.02PheThr: 2.02 ± 0.043	3.187PheVal: 3.187 ± 0.063	0.399PheTrp: 0.399 ± 0.017	0.881PheTyr: 0.881 ± 0.029	0.001PheXaa: 0.001 ± 0.001
Gly	7.724GlyAla: 7.724 ± 0.101	0.781GlyCys: 0.781 ± 0.03	6.613GlyAsp: 6.613 ± 0.094	6.99GlyGlu: 6.99 ± 0.091	2.953GlyPhe: 2.953 ± 0.052	7.038GlyGly: 7.038 ± 0.107	1.61GlyHis: 1.61 ± 0.041	4.547GlyIle: 4.547 ± 0.073	1.742GlyLys: 1.742 ± 0.041	7.059GlyLeu: 7.059 ± 0.099	1.632GlyMet: 1.632 ± 0.037	2.175GlyAsn: 2.175 ± 0.045	3.323GlyPro: 3.323 ± 0.059	2.006GlyGln: 2.006 ± 0.04	4.595GlyArg: 4.595 ± 0.067	5.321GlySer: 5.321 ± 0.071	6.535GlyThr: 6.535 ± 0.09	6.851GlyVal: 6.851 ± 0.076	1.096GlyTrp: 1.096 ± 0.034	2.743GlyTyr: 2.743 ± 0.05	0.002GlyXaa: 0.002 ± 0.001
His	1.972HisAla: 1.972 ± 0.041	0.221HisCys: 0.221 ± 0.012	1.848HisAsp: 1.848 ± 0.042	1.809HisGlu: 1.809 ± 0.037	0.543HisPhe: 0.543 ± 0.023	1.915HisGly: 1.915 ± 0.044	0.539HisHis: 0.539 ± 0.02	0.739HisIle: 0.739 ± 0.027	0.289HisLys: 0.289 ± 0.015	1.743HisLeu: 1.743 ± 0.043	0.309HisMet: 0.309 ± 0.014	0.446HisAsn: 0.446 ± 0.02	1.246HisPro: 1.246 ± 0.032	0.517HisGln: 0.517 ± 0.023	1.303HisArg: 1.303 ± 0.028	0.914HisSer: 0.914 ± 0.026	1.099HisThr: 1.099 ± 0.029	1.802HisVal: 1.802 ± 0.038	0.237HisTrp: 0.237 ± 0.016	0.581HisTyr: 0.581 ± 0.019	0.002HisXaa: 0.002 ± 0.001
Ile	5.442IleAla: 5.442 ± 0.078	0.307IleCys: 0.307 ± 0.016	4.734IleAsp: 4.734 ± 0.071	4.733IleGlu: 4.733 ± 0.075	1.064IlePhe: 1.064 ± 0.032	4.452IleGly: 4.452 ± 0.072	0.874IleHis: 0.874 ± 0.029	1.635IleIle: 1.635 ± 0.043	0.7IleLys: 0.7 ± 0.027	3.221IleLeu: 3.221 ± 0.061	0.572IleMet: 0.572 ± 0.024	1.086IleAsn: 1.086 ± 0.029	2.175IlePro: 2.175 ± 0.044	1.162IleGln: 1.162 ± 0.035	2.655IleArg: 2.655 ± 0.055	2.427IleSer: 2.427 ± 0.044	2.851IleThr: 2.851 ± 0.055	4.128IleVal: 4.128 ± 0.072	0.388IleTrp: 0.388 ± 0.02	1.003IleTyr: 1.003 ± 0.03	0.003IleXaa: 0.003 ± 0.002
Lys	1.568LysAla: 1.568 ± 0.04	0.094LysCys: 0.094 ± 0.009	0.981LysAsp: 0.981 ± 0.028	1.158LysGlu: 1.158 ± 0.04	0.457LysPhe: 0.457 ± 0.02	1.153LysGly: 1.153 ± 0.029	0.494LysHis: 0.494 ± 0.021	0.796LysIle: 0.796 ± 0.026	0.465LysLys: 0.465 ± 0.023	1.507LysLeu: 1.507 ± 0.038	0.369LysMet: 0.369 ± 0.018	0.55LysAsn: 0.55 ± 0.021	0.896LysPro: 0.896 ± 0.029	0.674LysGln: 0.674 ± 0.029	1.574LysArg: 1.574 ± 0.034	1.139LysSer: 1.139 ± 0.032	1.256LysThr: 1.256 ± 0.034	0.976LysVal: 0.976 ± 0.035	0.193LysTrp: 0.193 ± 0.013	0.516LysTyr: 0.516 ± 0.018	0.001LysXaa: 0.001 ± 0.001
Leu	10.662LeuAla: 10.662 ± 0.109	0.657LeuCys: 0.657 ± 0.021	7.09LeuAsp: 7.09 ± 0.091	8.629LeuGlu: 8.629 ± 0.108	3.091LeuPhe: 3.091 ± 0.059	7.469LeuGly: 7.469 ± 0.114	1.491LeuHis: 1.491 ± 0.036	3.231LeuIle: 3.231 ± 0.071	1.365LeuLys: 1.365 ± 0.036	8.429LeuLeu: 8.429 ± 0.117	1.219LeuMet: 1.219 ± 0.032	1.787LeuAsn: 1.787 ± 0.041	4.027LeuPro: 4.027 ± 0.059	2.147LeuGln: 2.147 ± 0.045	4.807LeuArg: 4.807 ± 0.077	5.501LeuSer: 5.501 ± 0.065	5.301LeuThr: 5.301 ± 0.067	7.957LeuVal: 7.957 ± 0.104	0.871LeuTrp: 0.871 ± 0.03	2.203LeuTyr: 2.203 ± 0.043	0.003LeuXaa: 0.003 ± 0.002
Met	1.844MetAla: 1.844 ± 0.039	0.123MetCys: 0.123 ± 0.009	1.215MetAsp: 1.215 ± 0.038	1.057MetGlu: 1.057 ± 0.027	0.541MetPhe: 0.541 ± 0.023	1.416MetGly: 1.416 ± 0.04	0.346MetHis: 0.346 ± 0.017	0.804MetIle: 0.804 ± 0.033	0.393MetLys: 0.393 ± 0.018	1.471MetLeu: 1.471 ± 0.037	0.316MetMet: 0.316 ± 0.016	0.623MetAsn: 0.623 ± 0.022	0.745MetPro: 0.745 ± 0.021	0.51MetGln: 0.51 ± 0.02	1.046MetArg: 1.046 ± 0.032	1.413MetSer: 1.413 ± 0.032	1.616MetThr: 1.616 ± 0.037	1.216MetVal: 1.216 ± 0.033	0.169MetTrp: 0.169 ± 0.013	0.409MetTyr: 0.409 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.838AsnAla: 2.838 ± 0.049	0.243AsnCys: 0.243 ± 0.013	1.858AsnAsp: 1.858 ± 0.044	2.083AsnGlu: 2.083 ± 0.042	0.669AsnPhe: 0.669 ± 0.022	2.324AsnGly: 2.324 ± 0.056	0.532AsnHis: 0.532 ± 0.022	0.919AsnIle: 0.919 ± 0.031	0.411AsnLys: 0.411 ± 0.02	1.913AsnLeu: 1.913 ± 0.041	0.428AsnMet: 0.428 ± 0.019	0.592AsnAsn: 0.592 ± 0.025	1.573AsnPro: 1.573 ± 0.035	0.695AsnGln: 0.695 ± 0.024	1.785AsnArg: 1.785 ± 0.039	1.353AsnSer: 1.353 ± 0.033	1.435AsnThr: 1.435 ± 0.041	2.258AsnVal: 2.258 ± 0.048	0.363AsnTrp: 0.363 ± 0.018	0.726AsnTyr: 0.726 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	4.939ProAla: 4.939 ± 0.072	0.243ProCys: 0.243 ± 0.014	4.762ProAsp: 4.762 ± 0.066	4.374ProGlu: 4.374 ± 0.061	1.579ProPhe: 1.579 ± 0.034	3.659ProGly: 3.659 ± 0.063	0.926ProHis: 0.926 ± 0.029	2.307ProIle: 2.307 ± 0.044	0.796ProLys: 0.796 ± 0.029	3.745ProLeu: 3.745 ± 0.052	0.825ProMet: 0.825 ± 0.027	1.357ProAsn: 1.357 ± 0.035	2.156ProPro: 2.156 ± 0.047	1.046ProGln: 1.046 ± 0.033	2.246ProArg: 2.246 ± 0.051	2.763ProSer: 2.763 ± 0.052	3.369ProThr: 3.369 ± 0.059	3.889ProVal: 3.889 ± 0.056	0.538ProTrp: 0.538 ± 0.023	1.146ProTyr: 1.146 ± 0.026	0.002ProXaa: 0.002 ± 0.001
Gln	2.402GlnAla: 2.402 ± 0.046	0.184GlnCys: 0.184 ± 0.012	1.439GlnAsp: 1.439 ± 0.037	1.836GlnGlu: 1.836 ± 0.051	1.14GlnPhe: 1.14 ± 0.032	1.659GlnGly: 1.659 ± 0.042	0.574GlnHis: 0.574 ± 0.025	1.194GlnIle: 1.194 ± 0.034	0.504GlnLys: 0.504 ± 0.021	2.489GlnLeu: 2.489 ± 0.051	0.552GlnMet: 0.552 ± 0.021	0.828GlnAsn: 0.828 ± 0.028	1.328GlnPro: 1.328 ± 0.031	1.102GlnGln: 1.102 ± 0.037	1.991GlnArg: 1.991 ± 0.043	1.79GlnSer: 1.79 ± 0.042	1.922GlnThr: 1.922 ± 0.041	1.765GlnVal: 1.765 ± 0.038	0.351GlnTrp: 0.351 ± 0.018	0.924GlnTyr: 0.924 ± 0.027	0.002GlnXaa: 0.002 ± 0.001
Arg	6.024ArgAla: 6.024 ± 0.079	0.506ArgCys: 0.506 ± 0.024	4.972ArgAsp: 4.972 ± 0.072	6.518ArgGlu: 6.518 ± 0.087	2.163ArgPhe: 2.163 ± 0.045	4.136ArgGly: 4.136 ± 0.057	1.208ArgHis: 1.208 ± 0.032	3.075ArgIle: 3.075 ± 0.055	1.306ArgLys: 1.306 ± 0.036	5.69ArgLeu: 5.69 ± 0.074	1.247ArgMet: 1.247 ± 0.03	1.709ArgAsn: 1.709 ± 0.036	2.539ArgPro: 2.539 ± 0.055	1.718ArgGln: 1.718 ± 0.041	4.716ArgArg: 4.716 ± 0.065	3.814ArgSer: 3.814 ± 0.057	4.547ArgThr: 4.547 ± 0.061	4.804ArgVal: 4.804 ± 0.065	0.791ArgTrp: 0.791 ± 0.027	1.991ArgTyr: 1.991 ± 0.041	0.003ArgXaa: 0.003 ± 0.002
Ser	5.572SerAla: 5.572 ± 0.077	0.325SerCys: 0.325 ± 0.018	4.857SerAsp: 4.857 ± 0.068	4.652SerGlu: 4.652 ± 0.074	1.881SerPhe: 1.881 ± 0.045	5.425SerGly: 5.425 ± 0.064	1.125SerHis: 1.125 ± 0.028	2.93SerIle: 2.93 ± 0.053	1.163SerLys: 1.163 ± 0.03	4.991SerLeu: 4.991 ± 0.069	1.167SerMet: 1.167 ± 0.03	1.69SerAsn: 1.69 ± 0.043	2.751SerPro: 2.751 ± 0.053	1.545SerGln: 1.545 ± 0.04	3.389SerArg: 3.389 ± 0.059	3.721SerSer: 3.721 ± 0.072	3.891SerThr: 3.891 ± 0.062	4.841SerVal: 4.841 ± 0.064	0.622SerTrp: 0.622 ± 0.023	1.471SerTyr: 1.471 ± 0.031	0.001SerXaa: 0.001 ± 0.001
Thr	8.06ThrAla: 8.06 ± 0.096	0.422ThrCys: 0.422 ± 0.02	6.646ThrAsp: 6.646 ± 0.092	5.42ThrGlu: 5.42 ± 0.079	2.114ThrPhe: 2.114 ± 0.039	6.257ThrGly: 6.257 ± 0.077	1.294ThrHis: 1.294 ± 0.027	3.703ThrIle: 3.703 ± 0.057	1.034ThrLys: 1.034 ± 0.026	5.87ThrLeu: 5.87 ± 0.078	1.158ThrMet: 1.158 ± 0.029	1.75ThrAsn: 1.75 ± 0.043	3.501ThrPro: 3.501 ± 0.057	1.602ThrGln: 1.602 ± 0.041	3.468ThrArg: 3.468 ± 0.055	3.253ThrSer: 3.253 ± 0.055	4.961ThrThr: 4.961 ± 0.068	7.153ThrVal: 7.153 ± 0.089	0.68ThrTrp: 0.68 ± 0.026	1.719ThrTyr: 1.719 ± 0.035	0.006ThrXaa: 0.006 ± 0.002
Val	9.039ValAla: 9.039 ± 0.107	0.616ValCys: 0.616 ± 0.023	7.162ValAsp: 7.162 ± 0.083	6.759ValGlu: 6.759 ± 0.086	2.807ValPhe: 2.807 ± 0.053	6.92ValGly: 6.92 ± 0.09	1.557ValHis: 1.557 ± 0.032	3.648ValIle: 3.648 ± 0.064	1.176ValLys: 1.176 ± 0.033	7.69ValLeu: 7.69 ± 0.103	1.277ValMet: 1.277 ± 0.035	1.857ValAsn: 1.857 ± 0.045	4.205ValPro: 4.205 ± 0.064	1.974ValGln: 1.974 ± 0.04	5.052ValArg: 5.052 ± 0.073	5.031ValSer: 5.031 ± 0.061	5.957ValThr: 5.957 ± 0.079	7.562ValVal: 7.562 ± 0.108	0.783ValTrp: 0.783 ± 0.026	2.002ValTyr: 2.002 ± 0.043	0.002ValXaa: 0.002 ± 0.001
Trp	0.913TrpAla: 0.913 ± 0.029	0.102TrpCys: 0.102 ± 0.01	0.825TrpAsp: 0.825 ± 0.026	0.857TrpGlu: 0.857 ± 0.034	0.456TrpPhe: 0.456 ± 0.02	0.842TrpGly: 0.842 ± 0.032	0.257TrpHis: 0.257 ± 0.014	0.561TrpIle: 0.561 ± 0.023	0.285TrpLys: 0.285 ± 0.016	1.202TrpLeu: 1.202 ± 0.034	0.238TrpMet: 0.238 ± 0.013	0.432TrpAsn: 0.432 ± 0.019	0.442TrpPro: 0.442 ± 0.019	0.398TrpGln: 0.398 ± 0.021	0.799TrpArg: 0.799 ± 0.03	0.607TrpSer: 0.607 ± 0.021	0.819TrpThr: 0.819 ± 0.028	0.762TrpVal: 0.762 ± 0.03	0.184TrpTrp: 0.184 ± 0.013	0.356TrpTyr: 0.356 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.709TyrAla: 2.709 ± 0.053	0.268TyrCys: 0.268 ± 0.015	2.635TyrAsp: 2.635 ± 0.041	2.598TyrGlu: 2.598 ± 0.053	0.841TyrPhe: 0.841 ± 0.026	2.346TyrGly: 2.346 ± 0.05	0.666TyrHis: 0.666 ± 0.025	0.816TyrIle: 0.816 ± 0.026	0.404TyrLys: 0.404 ± 0.018	2.309TyrLeu: 2.309 ± 0.05	0.386TyrMet: 0.386 ± 0.02	0.64TyrAsn: 0.64 ± 0.024	1.265TyrPro: 1.265 ± 0.033	0.733TyrGln: 0.733 ± 0.028	1.836TyrArg: 1.836 ± 0.045	1.276TyrSer: 1.276 ± 0.034	1.542TyrThr: 1.542 ± 0.038	2.181TyrVal: 2.181 ± 0.041	0.356TyrTrp: 0.356 ± 0.018	0.871TyrTyr: 0.871 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.001XaaCys: 0.001 ± 0.001	0.002XaaAsp: 0.002 ± 0.001	0.002XaaGlu: 0.002 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.002XaaHis: 0.002 ± 0.001	0.003XaaIle: 0.003 ± 0.002	0.001XaaLys: 0.001 ± 0.001	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.001	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.006XaaArg: 0.006 ± 0.002	0.005XaaSer: 0.005 ± 0.002	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4175 proteins (1209462 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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