Amino acid dipepetide frequency for Chryseobacterium hominis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.019AlaAla: 4.019 ± 0.089
0.482AlaCys: 0.482 ± 0.027
3.574AlaAsp: 3.574 ± 0.069
4.472AlaGlu: 4.472 ± 0.089
3.14AlaPhe: 3.14 ± 0.067
4.263AlaGly: 4.263 ± 0.092
0.947AlaHis: 0.947 ± 0.037
4.742AlaIle: 4.742 ± 0.082
5.176AlaLys: 5.176 ± 0.089
5.766AlaLeu: 5.766 ± 0.084
1.601AlaMet: 1.601 ± 0.05
3.333AlaAsn: 3.333 ± 0.076
1.634AlaPro: 1.634 ± 0.047
2.403AlaGln: 2.403 ± 0.062
1.956AlaArg: 1.956 ± 0.051
3.917AlaSer: 3.917 ± 0.083
3.34AlaThr: 3.34 ± 0.075
4.127AlaVal: 4.127 ± 0.08
0.604AlaTrp: 0.604 ± 0.031
2.403AlaTyr: 2.403 ± 0.051
0.0AlaXaa: 0.0 ± 0.0
Cys
0.411CysAla: 0.411 ± 0.023
0.112CysCys: 0.112 ± 0.012
0.411CysAsp: 0.411 ± 0.023
0.452CysGlu: 0.452 ± 0.023
0.422CysPhe: 0.422 ± 0.023
0.662CysGly: 0.662 ± 0.037
0.172CysHis: 0.172 ± 0.018
0.579CysIle: 0.579 ± 0.028
0.521CysLys: 0.521 ± 0.027
0.637CysLeu: 0.637 ± 0.028
0.144CysMet: 0.144 ± 0.013
0.4CysAsn: 0.4 ± 0.023
0.318CysPro: 0.318 ± 0.025
0.202CysGln: 0.202 ± 0.016
0.24CysArg: 0.24 ± 0.018
0.49CysSer: 0.49 ± 0.023
0.341CysThr: 0.341 ± 0.023
0.436CysVal: 0.436 ± 0.022
0.054CysTrp: 0.054 ± 0.009
0.264CysTyr: 0.264 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
3.377AspAla: 3.377 ± 0.062
0.396AspCys: 0.396 ± 0.024
2.963AspAsp: 2.963 ± 0.074
4.242AspGlu: 4.242 ± 0.093
4.108AspPhe: 4.108 ± 0.071
3.197AspGly: 3.197 ± 0.068
0.837AspHis: 0.837 ± 0.033
4.438AspIle: 4.438 ± 0.076
4.555AspLys: 4.555 ± 0.085
5.276AspLeu: 5.276 ± 0.074
1.107AspMet: 1.107 ± 0.04
3.213AspAsn: 3.213 ± 0.063
1.545AspPro: 1.545 ± 0.042
1.568AspGln: 1.568 ± 0.045
1.835AspArg: 1.835 ± 0.046
3.271AspSer: 3.271 ± 0.064
2.147AspThr: 2.147 ± 0.05
3.53AspVal: 3.53 ± 0.062
0.764AspTrp: 0.764 ± 0.034
2.981AspTyr: 2.981 ± 0.066
0.0AspXaa: 0.0 ± 0.0
Glu
3.994GluAla: 3.994 ± 0.084
0.314GluCys: 0.314 ± 0.021
3.543GluAsp: 3.543 ± 0.068
5.077GluGlu: 5.077 ± 0.11
3.377GluPhe: 3.377 ± 0.069
3.276GluGly: 3.276 ± 0.071
1.008GluHis: 1.008 ± 0.038
6.165GluIle: 6.165 ± 0.091
7.299GluLys: 7.299 ± 0.107
6.16GluLeu: 6.16 ± 0.106
1.716GluMet: 1.716 ± 0.044
5.406GluAsn: 5.406 ± 0.095
1.522GluPro: 1.522 ± 0.05
2.382GluGln: 2.382 ± 0.054
2.446GluArg: 2.446 ± 0.064
3.471GluSer: 3.471 ± 0.063
3.623GluThr: 3.623 ± 0.065
4.101GluVal: 4.101 ± 0.079
0.667GluTrp: 0.667 ± 0.031
2.317GluTyr: 2.317 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
3.367PheAla: 3.367 ± 0.06
0.537PheCys: 0.537 ± 0.029
3.404PheAsp: 3.404 ± 0.07
3.39PheGlu: 3.39 ± 0.07
3.074PhePhe: 3.074 ± 0.077
3.964PheGly: 3.964 ± 0.076
0.896PheHis: 0.896 ± 0.034
3.992PheIle: 3.992 ± 0.069
3.62PheLys: 3.62 ± 0.067
5.169PheLeu: 5.169 ± 0.1
1.129PheMet: 1.129 ± 0.037
3.021PheAsn: 3.021 ± 0.072
1.984PhePro: 1.984 ± 0.052
1.766PheGln: 1.766 ± 0.048
2.004PheArg: 2.004 ± 0.051
4.336PheSer: 4.336 ± 0.084
2.807PheThr: 2.807 ± 0.064
3.3PheVal: 3.3 ± 0.066
0.659PheTrp: 0.659 ± 0.028
2.435PheTyr: 2.435 ± 0.059
0.0PheXaa: 0.0 ± 0.0
Gly
3.903GlyAla: 3.903 ± 0.084
0.551GlyCys: 0.551 ± 0.03
3.013GlyAsp: 3.013 ± 0.066
3.489GlyGlu: 3.489 ± 0.071
3.723GlyPhe: 3.723 ± 0.07
4.314GlyGly: 4.314 ± 0.098
1.002GlyHis: 1.002 ± 0.042
5.474GlyIle: 5.474 ± 0.097
5.666GlyLys: 5.666 ± 0.088
5.479GlyLeu: 5.479 ± 0.088
1.607GlyMet: 1.607 ± 0.049
3.762GlyAsn: 3.762 ± 0.089
1.151GlyPro: 1.151 ± 0.042
1.918GlyGln: 1.918 ± 0.047
2.069GlyArg: 2.069 ± 0.049
3.921GlySer: 3.921 ± 0.077
3.734GlyThr: 3.734 ± 0.083
4.092GlyVal: 4.092 ± 0.073
0.698GlyTrp: 0.698 ± 0.034
2.602GlyTyr: 2.602 ± 0.056
0.0GlyXaa: 0.0 ± 0.0
His
0.846HisAla: 0.846 ± 0.033
0.198HisCys: 0.198 ± 0.015
0.721HisAsp: 0.721 ± 0.032
0.859HisGlu: 0.859 ± 0.034
1.15HisPhe: 1.15 ± 0.04
0.914HisGly: 0.914 ± 0.04
0.512HisHis: 0.512 ± 0.027
1.282HisIle: 1.282 ± 0.049
1.117HisLys: 1.117 ± 0.037
1.678HisLeu: 1.678 ± 0.046
0.293HisMet: 0.293 ± 0.019
0.911HisAsn: 0.911 ± 0.031
0.893HisPro: 0.893 ± 0.033
0.81HisGln: 0.81 ± 0.032
0.618HisArg: 0.618 ± 0.029
1.085HisSer: 1.085 ± 0.037
0.823HisThr: 0.823 ± 0.032
0.65HisVal: 0.65 ± 0.029
0.187HisTrp: 0.187 ± 0.018
0.852HisTyr: 0.852 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.203IleAla: 5.203 ± 0.093
0.7IleCys: 0.7 ± 0.026
4.792IleAsp: 4.792 ± 0.073
5.284IleGlu: 5.284 ± 0.084
4.307IlePhe: 4.307 ± 0.083
5.064IleGly: 5.064 ± 0.088
1.293IleHis: 1.293 ± 0.042
6.572IleIle: 6.572 ± 0.121
6.205IleLys: 6.205 ± 0.092
7.688IleLeu: 7.688 ± 0.102
1.413IleMet: 1.413 ± 0.043
4.935IleAsn: 4.935 ± 0.079
3.415IlePro: 3.415 ± 0.063
2.63IleGln: 2.63 ± 0.062
2.619IleArg: 2.619 ± 0.064
6.126IleSer: 6.126 ± 0.104
4.252IleThr: 4.252 ± 0.074
4.536IleVal: 4.536 ± 0.075
0.721IleTrp: 0.721 ± 0.03
2.887IleTyr: 2.887 ± 0.059
0.0IleXaa: 0.0 ± 0.0
Lys
5.08LysAla: 5.08 ± 0.091
0.4LysCys: 0.4 ± 0.024
5.06LysAsp: 5.06 ± 0.082
6.286LysGlu: 6.286 ± 0.089
3.683LysPhe: 3.683 ± 0.075
4.424LysGly: 4.424 ± 0.073
1.311LysHis: 1.311 ± 0.042
7.821LysIle: 7.821 ± 0.098
7.72LysLys: 7.72 ± 0.09
7.016LysLeu: 7.016 ± 0.102
2.402LysMet: 2.402 ± 0.055
6.424LysAsn: 6.424 ± 0.105
2.71LysPro: 2.71 ± 0.058
2.915LysGln: 2.915 ± 0.067
2.678LysArg: 2.678 ± 0.056
5.16LysSer: 5.16 ± 0.087
4.99LysThr: 4.99 ± 0.077
4.948LysVal: 4.948 ± 0.083
0.726LysTrp: 0.726 ± 0.033
3.254LysTyr: 3.254 ± 0.06
0.0LysXaa: 0.0 ± 0.0
Leu
5.878LeuAla: 5.878 ± 0.102
0.682LeuCys: 0.682 ± 0.028
5.058LeuAsp: 5.058 ± 0.085
6.246LeuGlu: 6.246 ± 0.109
4.652LeuPhe: 4.652 ± 0.077
5.936LeuGly: 5.936 ± 0.104
1.453LeuHis: 1.453 ± 0.046
6.897LeuIle: 6.897 ± 0.107
8.204LeuLys: 8.204 ± 0.125
8.062LeuLeu: 8.062 ± 0.129
2.288LeuMet: 2.288 ± 0.058
5.434LeuAsn: 5.434 ± 0.103
3.54LeuPro: 3.54 ± 0.073
3.323LeuGln: 3.323 ± 0.063
3.162LeuArg: 3.162 ± 0.067
6.648LeuSer: 6.648 ± 0.105
4.763LeuThr: 4.763 ± 0.084
5.125LeuVal: 5.125 ± 0.085
0.808LeuTrp: 0.808 ± 0.037
3.1LeuTyr: 3.1 ± 0.068
0.0LeuXaa: 0.0 ± 0.0
Met
1.516MetAla: 1.516 ± 0.04
0.116MetCys: 0.116 ± 0.012
1.183MetAsp: 1.183 ± 0.04
1.496MetGlu: 1.496 ± 0.046
0.981MetPhe: 0.981 ± 0.034
1.374MetGly: 1.374 ± 0.046
0.376MetHis: 0.376 ± 0.023
1.815MetIle: 1.815 ± 0.049
2.539MetLys: 2.539 ± 0.056
2.006MetLeu: 2.006 ± 0.048
0.764MetMet: 0.764 ± 0.03
1.465MetAsn: 1.465 ± 0.043
0.88MetPro: 0.88 ± 0.034
0.852MetGln: 0.852 ± 0.034
0.856MetArg: 0.856 ± 0.033
1.465MetSer: 1.465 ± 0.04
1.241MetThr: 1.241 ± 0.032
1.297MetVal: 1.297 ± 0.045
0.17MetTrp: 0.17 ± 0.015
0.636MetTyr: 0.636 ± 0.027
0.0MetXaa: 0.0 ± 0.0
Asn
3.794AsnAla: 3.794 ± 0.069
0.42AsnCys: 0.42 ± 0.025
3.147AsnAsp: 3.147 ± 0.07
3.663AsnGlu: 3.663 ± 0.073
3.525AsnPhe: 3.525 ± 0.073
4.011AsnGly: 4.011 ± 0.089
1.15AsnHis: 1.15 ± 0.037
5.247AsnIle: 5.247 ± 0.093
4.402AsnLys: 4.402 ± 0.089
6.158AsnLeu: 6.158 ± 0.11
1.254AsnMet: 1.254 ± 0.036
3.942AsnAsn: 3.942 ± 0.094
3.063AsnPro: 3.063 ± 0.061
2.69AsnGln: 2.69 ± 0.057
2.079AsnArg: 2.079 ± 0.049
3.97AsnSer: 3.97 ± 0.093
2.953AsnThr: 2.953 ± 0.077
3.766AsnVal: 3.766 ± 0.077
0.764AsnTrp: 0.764 ± 0.034
3.051AsnTyr: 3.051 ± 0.085
0.0AsnXaa: 0.0 ± 0.0
Pro
2.145ProAla: 2.145 ± 0.057
0.2ProCys: 0.2 ± 0.013
2.001ProAsp: 2.001 ± 0.052
2.985ProGlu: 2.985 ± 0.064
1.824ProPhe: 1.824 ± 0.047
1.76ProGly: 1.76 ± 0.051
0.561ProHis: 0.561 ± 0.029
2.574ProIle: 2.574 ± 0.059
3.01ProLys: 3.01 ± 0.065
2.675ProLeu: 2.675 ± 0.061
0.809ProMet: 0.809 ± 0.029
2.202ProAsn: 2.202 ± 0.056
0.752ProPro: 0.752 ± 0.04
1.228ProGln: 1.228 ± 0.033
0.956ProArg: 0.956 ± 0.034
2.099ProSer: 2.099 ± 0.052
1.934ProThr: 1.934 ± 0.047
2.363ProVal: 2.363 ± 0.052
0.293ProTrp: 0.293 ± 0.021
1.452ProTyr: 1.452 ± 0.045
0.0ProXaa: 0.0 ± 0.0
Gln
1.984GlnAla: 1.984 ± 0.053
0.16GlnCys: 0.16 ± 0.015
1.721GlnAsp: 1.721 ± 0.048
2.297GlnGlu: 2.297 ± 0.057
1.814GlnPhe: 1.814 ± 0.053
1.743GlnGly: 1.743 ± 0.054
0.574GlnHis: 0.574 ± 0.027
2.955GlnIle: 2.955 ± 0.054
3.595GlnLys: 3.595 ± 0.069
3.317GlnLeu: 3.317 ± 0.073
0.909GlnMet: 0.909 ± 0.033
2.774GlnAsn: 2.774 ± 0.06
1.117GlnPro: 1.117 ± 0.039
1.522GlnGln: 1.522 ± 0.049
1.264GlnArg: 1.264 ± 0.042
2.094GlnSer: 2.094 ± 0.056
2.006GlnThr: 2.006 ± 0.056
1.901GlnVal: 1.901 ± 0.054
0.365GlnTrp: 0.365 ± 0.025
1.492GlnTyr: 1.492 ± 0.048
0.0GlnXaa: 0.0 ± 0.0
Arg
1.854ArgAla: 1.854 ± 0.045
0.2ArgCys: 0.2 ± 0.014
1.706ArgAsp: 1.706 ± 0.046
2.294ArgGlu: 2.294 ± 0.057
1.948ArgPhe: 1.948 ± 0.048
1.77ArgGly: 1.77 ± 0.052
0.595ArgHis: 0.595 ± 0.028
2.977ArgIle: 2.977 ± 0.056
3.214ArgLys: 3.214 ± 0.067
3.08ArgLeu: 3.08 ± 0.066
0.868ArgMet: 0.868 ± 0.033
2.36ArgAsn: 2.36 ± 0.063
1.058ArgPro: 1.058 ± 0.039
1.234ArgGln: 1.234 ± 0.038
1.325ArgArg: 1.325 ± 0.044
1.808ArgSer: 1.808 ± 0.055
1.74ArgThr: 1.74 ± 0.055
1.875ArgVal: 1.875 ± 0.047
0.334ArgTrp: 0.334 ± 0.023
1.32ArgTyr: 1.32 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
4.099SerAla: 4.099 ± 0.085
0.539SerCys: 0.539 ± 0.027
3.658SerAsp: 3.658 ± 0.074
4.655SerGlu: 4.655 ± 0.081
3.761SerPhe: 3.761 ± 0.071
4.82SerGly: 4.82 ± 0.097
1.074SerHis: 1.074 ± 0.035
4.791SerIle: 4.791 ± 0.08
5.219SerLys: 5.219 ± 0.087
5.953SerLeu: 5.953 ± 0.095
1.28SerMet: 1.28 ± 0.041
3.63SerAsn: 3.63 ± 0.08
2.171SerPro: 2.171 ± 0.047
2.476SerGln: 2.476 ± 0.062
2.105SerArg: 2.105 ± 0.059
4.19SerSer: 4.19 ± 0.086
3.141SerThr: 3.141 ± 0.086
4.23SerVal: 4.23 ± 0.079
0.647SerTrp: 0.647 ± 0.031
2.611SerTyr: 2.611 ± 0.07
0.0SerXaa: 0.0 ± 0.0
Thr
3.557ThrAla: 3.557 ± 0.086
0.309ThrCys: 0.309 ± 0.021
3.163ThrAsp: 3.163 ± 0.066
3.535ThrGlu: 3.535 ± 0.079
2.796ThrPhe: 2.796 ± 0.069
3.738ThrGly: 3.738 ± 0.08
0.827ThrHis: 0.827 ± 0.033
4.158ThrIle: 4.158 ± 0.069
4.003ThrLys: 4.003 ± 0.07
4.781ThrLeu: 4.781 ± 0.082
0.98ThrMet: 0.98 ± 0.033
2.891ThrAsn: 2.891 ± 0.068
2.201ThrPro: 2.201 ± 0.055
1.832ThrGln: 1.832 ± 0.051
1.517ThrArg: 1.517 ± 0.05
3.45ThrSer: 3.45 ± 0.079
2.998ThrThr: 2.998 ± 0.079
3.332ThrVal: 3.332 ± 0.075
0.486ThrTrp: 0.486 ± 0.026
2.02ThrTyr: 2.02 ± 0.052
0.0ThrXaa: 0.0 ± 0.0
Val
4.055ValAla: 4.055 ± 0.088
0.516ValCys: 0.516 ± 0.028
3.348ValAsp: 3.348 ± 0.064
3.982ValGlu: 3.982 ± 0.089
3.389ValPhe: 3.389 ± 0.08
3.755ValGly: 3.755 ± 0.079
0.87ValHis: 0.87 ± 0.036
4.642ValIle: 4.642 ± 0.097
4.774ValLys: 4.774 ± 0.083
5.636ValLeu: 5.636 ± 0.101
1.409ValMet: 1.409 ± 0.038
3.601ValAsn: 3.601 ± 0.075
2.174ValPro: 2.174 ± 0.055
1.663ValGln: 1.663 ± 0.042
1.987ValArg: 1.987 ± 0.049
4.262ValSer: 4.262 ± 0.072
3.203ValThr: 3.203 ± 0.069
3.917ValVal: 3.917 ± 0.081
0.587ValTrp: 0.587 ± 0.028
2.355ValTyr: 2.355 ± 0.055
0.0ValXaa: 0.0 ± 0.0
Trp
0.583TrpAla: 0.583 ± 0.03
0.071TrpCys: 0.071 ± 0.01
0.572TrpAsp: 0.572 ± 0.031
0.695TrpGlu: 0.695 ± 0.03
0.593TrpPhe: 0.593 ± 0.028
0.631TrpGly: 0.631 ± 0.033
0.17TrpHis: 0.17 ± 0.014
0.764TrpIle: 0.764 ± 0.033
0.958TrpLys: 0.958 ± 0.04
0.878TrpLeu: 0.878 ± 0.037
0.318TrpMet: 0.318 ± 0.021
0.735TrpAsn: 0.735 ± 0.033
0.189TrpPro: 0.189 ± 0.016
0.425TrpGln: 0.425 ± 0.023
0.358TrpArg: 0.358 ± 0.023
0.565TrpSer: 0.565 ± 0.026
0.524TrpThr: 0.524 ± 0.025
0.559TrpVal: 0.559 ± 0.029
0.137TrpTrp: 0.137 ± 0.014
0.396TrpTyr: 0.396 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.237TyrAla: 2.237 ± 0.053
0.363TyrCys: 0.363 ± 0.02
2.314TyrAsp: 2.314 ± 0.057
2.464TyrGlu: 2.464 ± 0.055
2.59TyrPhe: 2.59 ± 0.06
2.553TyrGly: 2.553 ± 0.069
0.769TyrHis: 0.769 ± 0.031
2.756TyrIle: 2.756 ± 0.061
3.208TyrLys: 3.208 ± 0.063
3.841TyrLeu: 3.841 ± 0.066
0.733TyrMet: 0.733 ± 0.035
2.609TyrAsn: 2.609 ± 0.071
1.506TyrPro: 1.506 ± 0.047
1.762TyrGln: 1.762 ± 0.048
1.49TyrArg: 1.49 ± 0.052
2.723TyrSer: 2.723 ± 0.064
2.014TyrThr: 2.014 ± 0.052
2.044TyrVal: 2.044 ± 0.053
0.45TyrTrp: 0.45 ± 0.023
1.92TyrTyr: 1.92 ± 0.057
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2619 proteins (818176 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski