Amino acid dipepetide frequency for Banana mild mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.071AlaAla: 2.071 ± 2.976
1.243AlaCys: 1.243 ± 0.662
2.486AlaAsp: 2.486 ± 0.892
1.243AlaGlu: 1.243 ± 2.309
3.314AlaPhe: 3.314 ± 1.845
2.071AlaGly: 2.071 ± 1.351
2.071AlaHis: 2.071 ± 0.836
5.8AlaIle: 5.8 ± 1.738
2.9AlaLys: 2.9 ± 1.381
3.314AlaLeu: 3.314 ± 4.027
1.243AlaMet: 1.243 ± 1.408
3.314AlaAsn: 3.314 ± 1.097
0.829AlaPro: 0.829 ± 0.441
1.657AlaGln: 1.657 ± 0.882
3.314AlaArg: 3.314 ± 1.342
2.486AlaSer: 2.486 ± 1.319
2.9AlaThr: 2.9 ± 1.176
3.728AlaVal: 3.728 ± 1.434
0.0AlaTrp: 0.0 ± 0.0
2.071AlaTyr: 2.071 ± 0.726
0.0AlaXaa: 0.0 ± 0.0
Cys
0.829CysAla: 0.829 ± 0.441
0.0CysCys: 0.0 ± 0.0
0.829CysAsp: 0.829 ± 1.244
0.414CysGlu: 0.414 ± 1.622
0.829CysPhe: 0.829 ± 0.441
1.243CysGly: 1.243 ± 1.648
0.829CysHis: 0.829 ± 1.818
2.071CysIle: 2.071 ± 0.799
2.071CysLys: 2.071 ± 1.103
1.657CysLeu: 1.657 ± 1.651
1.657CysMet: 1.657 ± 1.073
0.414CysAsn: 0.414 ± 0.221
0.829CysPro: 0.829 ± 0.688
0.414CysGln: 0.414 ± 0.221
1.657CysArg: 1.657 ± 1.376
1.657CysSer: 1.657 ± 0.882
0.829CysThr: 0.829 ± 0.441
0.414CysVal: 0.414 ± 0.221
0.414CysTrp: 0.414 ± 0.221
1.243CysTyr: 1.243 ± 1.408
0.0CysXaa: 0.0 ± 0.0
Asp
2.9AspAla: 2.9 ± 2.662
0.829AspCys: 0.829 ± 0.868
2.9AspAsp: 2.9 ± 1.544
6.214AspGlu: 6.214 ± 1.635
3.728AspPhe: 3.728 ± 1.059
3.314AspGly: 3.314 ± 1.319
0.414AspHis: 0.414 ± 0.221
2.9AspIle: 2.9 ± 1.176
2.071AspLys: 2.071 ± 0.799
5.8AspLeu: 5.8 ± 2.356
0.829AspMet: 0.829 ± 0.634
3.314AspAsn: 3.314 ± 1.909
2.486AspPro: 2.486 ± 0.892
1.243AspGln: 1.243 ± 0.662
2.486AspArg: 2.486 ± 0.892
1.657AspSer: 1.657 ± 1.765
0.829AspThr: 0.829 ± 0.441
3.728AspVal: 3.728 ± 1.546
0.414AspTrp: 0.414 ± 0.221
2.9AspTyr: 2.9 ± 1.21
0.0AspXaa: 0.0 ± 0.0
Glu
3.728GluAla: 3.728 ± 1.986
1.243GluCys: 1.243 ± 0.662
2.486GluAsp: 2.486 ± 1.573
10.356GluGlu: 10.356 ± 3.49
2.486GluPhe: 2.486 ± 0.892
2.071GluGly: 2.071 ± 0.799
0.829GluHis: 0.829 ± 0.868
5.8GluIle: 5.8 ± 2.202
8.699GluLys: 8.699 ± 3.72
9.942GluLeu: 9.942 ± 3.282
2.071GluMet: 2.071 ± 1.103
5.385GluAsn: 5.385 ± 1.908
2.071GluPro: 2.071 ± 0.799
2.486GluGln: 2.486 ± 1.46
3.314GluArg: 3.314 ± 1.342
4.143GluSer: 4.143 ± 1.739
4.143GluThr: 4.143 ± 1.673
4.971GluVal: 4.971 ± 2.798
0.829GluTrp: 0.829 ± 0.688
2.9GluTyr: 2.9 ± 1.176
0.0GluXaa: 0.0 ± 0.0
Phe
1.657PheAla: 1.657 ± 0.726
1.243PheCys: 1.243 ± 0.672
5.385PheAsp: 5.385 ± 1.734
5.385PheGlu: 5.385 ± 2.363
2.071PhePhe: 2.071 ± 1.103
2.9PheGly: 2.9 ± 1.024
1.657PheHis: 1.657 ± 0.882
3.314PheIle: 3.314 ± 1.674
3.728PheLys: 3.728 ± 1.059
6.214PheLeu: 6.214 ± 1.991
1.657PheMet: 1.657 ± 0.882
3.314PheAsn: 3.314 ± 1.106
1.243PhePro: 1.243 ± 0.662
1.657PheGln: 1.657 ± 1.736
0.829PheArg: 0.829 ± 0.688
4.557PheSer: 4.557 ± 2.427
2.9PheThr: 2.9 ± 1.371
4.143PheVal: 4.143 ± 1.666
0.0PheTrp: 0.0 ± 0.0
1.243PheTyr: 1.243 ± 0.786
0.0PheXaa: 0.0 ± 0.0
Gly
1.657GlyAla: 1.657 ± 1.106
1.243GlyCys: 1.243 ± 2.781
4.971GlyAsp: 4.971 ± 1.953
2.9GlyGlu: 2.9 ± 1.544
2.9GlyPhe: 2.9 ± 1.453
1.657GlyGly: 1.657 ± 2.725
0.414GlyHis: 0.414 ± 0.221
3.728GlyIle: 3.728 ± 1.55
4.143GlyLys: 4.143 ± 2.313
3.728GlyLeu: 3.728 ± 1.546
0.0GlyMet: 0.0 ± 0.0
3.728GlyAsn: 3.728 ± 1.281
0.414GlyPro: 0.414 ± 0.221
2.071GlyGln: 2.071 ± 1.642
2.486GlyArg: 2.486 ± 1.344
4.143GlySer: 4.143 ± 2.541
2.071GlyThr: 2.071 ± 2.392
2.9GlyVal: 2.9 ± 2.08
0.829GlyTrp: 0.829 ± 0.441
2.071GlyTyr: 2.071 ± 1.103
0.0GlyXaa: 0.0 ± 0.0
His
0.414HisAla: 0.414 ± 0.221
0.414HisCys: 0.414 ± 0.221
0.829HisAsp: 0.829 ± 0.441
0.829HisGlu: 0.829 ± 0.441
1.243HisPhe: 1.243 ± 1.156
1.657HisGly: 1.657 ± 1.736
0.829HisHis: 0.829 ± 1.244
3.314HisIle: 3.314 ± 1.319
1.657HisLys: 1.657 ± 1.89
2.071HisLeu: 2.071 ± 1.098
0.829HisMet: 0.829 ± 0.441
1.657HisAsn: 1.657 ± 2.725
0.414HisPro: 0.414 ± 0.221
0.0HisGln: 0.0 ± 0.0
1.657HisArg: 1.657 ± 0.762
2.071HisSer: 2.071 ± 1.098
0.414HisThr: 0.414 ± 0.221
2.486HisVal: 2.486 ± 2.313
0.414HisTrp: 0.414 ± 0.77
1.657HisTyr: 1.657 ± 0.762
0.0HisXaa: 0.0 ± 0.0
Ile
3.314IleAla: 3.314 ± 2.008
1.657IleCys: 1.657 ± 0.726
4.143IleAsp: 4.143 ± 1.666
6.214IleGlu: 6.214 ± 1.305
3.728IlePhe: 3.728 ± 1.986
1.657IleGly: 1.657 ± 0.882
2.486IleHis: 2.486 ± 2.098
4.971IleIle: 4.971 ± 2.472
5.8IleLys: 5.8 ± 2.049
5.8IleLeu: 5.8 ± 1.397
2.486IleMet: 2.486 ± 1.344
2.9IleAsn: 2.9 ± 2.354
1.657IlePro: 1.657 ± 1.343
1.657IleGln: 1.657 ± 0.762
3.728IleArg: 3.728 ± 1.966
5.385IleSer: 5.385 ± 1.329
4.557IleThr: 4.557 ± 1.604
4.143IleVal: 4.143 ± 1.599
0.0IleTrp: 0.0 ± 0.0
2.071IleTyr: 2.071 ± 1.098
0.0IleXaa: 0.0 ± 0.0
Lys
3.728LysAla: 3.728 ± 1.538
2.486LysCys: 2.486 ± 1.324
2.071LysAsp: 2.071 ± 0.799
9.528LysGlu: 9.528 ± 3.426
4.971LysPhe: 4.971 ± 1.637
4.971LysGly: 4.971 ± 2.015
0.414LysHis: 0.414 ± 1.363
6.214LysIle: 6.214 ± 2.398
9.528LysLys: 9.528 ± 2.407
5.385LysLeu: 5.385 ± 2.137
1.657LysMet: 1.657 ± 0.882
7.042LysAsn: 7.042 ± 2.996
2.486LysPro: 2.486 ± 1.715
2.071LysGln: 2.071 ± 0.799
7.042LysArg: 7.042 ± 2.2
5.8LysSer: 5.8 ± 1.45
2.486LysThr: 2.486 ± 1.324
3.728LysVal: 3.728 ± 1.454
0.0LysTrp: 0.0 ± 0.0
1.657LysTyr: 1.657 ± 0.856
0.0LysXaa: 0.0 ± 0.0
Leu
5.8LeuAla: 5.8 ± 2.102
1.657LeuCys: 1.657 ± 0.882
5.8LeuAsp: 5.8 ± 1.592
7.871LeuGlu: 7.871 ± 2.988
5.385LeuPhe: 5.385 ± 2.868
3.314LeuGly: 3.314 ± 1.183
1.657LeuHis: 1.657 ± 1.106
3.728LeuIle: 3.728 ± 2.261
8.699LeuLys: 8.699 ± 1.721
9.942LeuLeu: 9.942 ± 4.141
1.657LeuMet: 1.657 ± 0.754
5.8LeuAsn: 5.8 ± 1.705
4.143LeuPro: 4.143 ± 2.392
2.486LeuGln: 2.486 ± 0.892
3.728LeuArg: 3.728 ± 1.711
7.457LeuSer: 7.457 ± 3.076
4.557LeuThr: 4.557 ± 2.289
8.699LeuVal: 8.699 ± 3.085
0.0LeuTrp: 0.0 ± 0.0
1.243LeuTyr: 1.243 ± 0.662
0.0LeuXaa: 0.0 ± 0.0
Met
4.557MetAla: 4.557 ± 1.426
0.414MetCys: 0.414 ± 0.221
0.829MetAsp: 0.829 ± 0.441
0.829MetGlu: 0.829 ± 0.441
1.243MetPhe: 1.243 ± 0.662
0.414MetGly: 0.414 ± 0.221
0.414MetHis: 0.414 ± 0.221
2.071MetIle: 2.071 ± 1.103
1.657MetLys: 1.657 ± 0.882
1.243MetLeu: 1.243 ± 0.662
0.414MetMet: 0.414 ± 0.221
2.071MetAsn: 2.071 ± 0.799
1.657MetPro: 1.657 ± 0.726
0.829MetGln: 0.829 ± 0.441
2.071MetArg: 2.071 ± 0.836
3.314MetSer: 3.314 ± 1.845
0.414MetThr: 0.414 ± 0.77
0.829MetVal: 0.829 ± 0.688
0.0MetTrp: 0.0 ± 0.0
0.829MetTyr: 0.829 ± 1.503
0.0MetXaa: 0.0 ± 0.0
Asn
2.071AsnAla: 2.071 ± 0.726
2.486AsnCys: 2.486 ± 1.134
1.657AsnAsp: 1.657 ± 0.882
2.9AsnGlu: 2.9 ± 1.361
6.214AsnPhe: 6.214 ± 1.578
3.314AsnGly: 3.314 ± 1.387
2.486AsnHis: 2.486 ± 1.324
2.486AsnIle: 2.486 ± 1.581
3.728AsnLys: 3.728 ± 1.454
6.628AsnLeu: 6.628 ± 2.11
2.9AsnMet: 2.9 ± 1.929
3.314AsnAsn: 3.314 ± 1.097
1.657AsnPro: 1.657 ± 1.765
1.657AsnGln: 1.657 ± 0.882
2.9AsnArg: 2.9 ± 3.291
5.8AsnSer: 5.8 ± 1.473
2.486AsnThr: 2.486 ± 0.985
3.728AsnVal: 3.728 ± 1.281
0.0AsnTrp: 0.0 ± 0.0
2.486AsnTyr: 2.486 ± 1.236
0.0AsnXaa: 0.0 ± 0.0
Pro
0.414ProAla: 0.414 ± 0.221
1.243ProCys: 1.243 ± 1.408
1.657ProAsp: 1.657 ± 1.106
2.071ProGlu: 2.071 ± 0.836
1.243ProPhe: 1.243 ± 0.786
1.657ProGly: 1.657 ± 0.882
0.414ProHis: 0.414 ± 1.363
2.071ProIle: 2.071 ± 0.799
2.486ProLys: 2.486 ± 0.647
1.243ProLeu: 1.243 ± 1.446
0.414ProMet: 0.414 ± 0.221
0.414ProAsn: 0.414 ± 0.221
2.071ProPro: 2.071 ± 1.809
1.243ProGln: 1.243 ± 0.672
2.071ProArg: 2.071 ± 1.103
1.657ProSer: 1.657 ± 0.762
2.9ProThr: 2.9 ± 2.024
1.657ProVal: 1.657 ± 1.723
1.243ProTrp: 1.243 ± 0.662
2.486ProTyr: 2.486 ± 1.236
0.0ProXaa: 0.0 ± 0.0
Gln
1.243GlnAla: 1.243 ± 0.662
0.0GlnCys: 0.0 ± 0.0
0.414GlnAsp: 0.414 ± 0.221
1.657GlnGlu: 1.657 ± 0.762
2.486GlnPhe: 2.486 ± 0.985
1.243GlnGly: 1.243 ± 0.786
0.414GlnHis: 0.414 ± 0.77
0.414GlnIle: 0.414 ± 0.221
1.657GlnLys: 1.657 ± 0.726
4.143GlnLeu: 4.143 ± 1.786
0.414GlnMet: 0.414 ± 0.77
1.657GlnAsn: 1.657 ± 1.651
0.829GlnPro: 0.829 ± 0.688
0.414GlnGln: 0.414 ± 0.221
2.071GlnArg: 2.071 ± 1.103
2.9GlnSer: 2.9 ± 1.361
1.657GlnThr: 1.657 ± 0.882
2.486GlnVal: 2.486 ± 0.892
0.414GlnTrp: 0.414 ± 0.221
1.657GlnTyr: 1.657 ± 1.736
0.0GlnXaa: 0.0 ± 0.0
Arg
3.314ArgAla: 3.314 ± 1.406
0.414ArgCys: 0.414 ± 0.221
0.829ArgAsp: 0.829 ± 1.244
4.971ArgGlu: 4.971 ± 1.103
3.728ArgPhe: 3.728 ± 1.36
3.314ArgGly: 3.314 ± 1.965
1.657ArgHis: 1.657 ± 0.726
2.486ArgIle: 2.486 ± 1.134
4.557ArgLys: 4.557 ± 1.944
4.971ArgLeu: 4.971 ± 1.651
2.486ArgMet: 2.486 ± 1.142
3.728ArgAsn: 3.728 ± 1.454
1.243ArgPro: 1.243 ± 1.156
0.414ArgGln: 0.414 ± 0.77
2.9ArgArg: 2.9 ± 2.252
5.385ArgSer: 5.385 ± 2.427
1.657ArgThr: 1.657 ± 0.882
2.486ArgVal: 2.486 ± 0.647
0.414ArgTrp: 0.414 ± 0.221
2.071ArgTyr: 2.071 ± 1.103
0.0ArgXaa: 0.0 ± 0.0
Ser
2.486SerAla: 2.486 ± 1.375
0.829SerCys: 0.829 ± 0.868
4.971SerAsp: 4.971 ± 1.293
5.385SerGlu: 5.385 ± 0.82
3.728SerPhe: 3.728 ± 1.538
3.728SerGly: 3.728 ± 1.55
3.314SerHis: 3.314 ± 1.106
2.9SerIle: 2.9 ± 1.544
7.042SerLys: 7.042 ± 1.108
7.042SerLeu: 7.042 ± 2.084
2.071SerMet: 2.071 ± 1.098
3.314SerAsn: 3.314 ± 1.342
2.071SerPro: 2.071 ± 1.103
3.314SerGln: 3.314 ± 1.765
4.557SerArg: 4.557 ± 1.426
5.385SerSer: 5.385 ± 3.299
2.071SerThr: 2.071 ± 0.799
6.214SerVal: 6.214 ± 3.032
0.414SerTrp: 0.414 ± 0.77
3.728SerTyr: 3.728 ± 3.066
0.0SerXaa: 0.0 ± 0.0
Thr
2.486ThrAla: 2.486 ± 1.375
0.414ThrCys: 0.414 ± 1.622
3.728ThrAsp: 3.728 ± 1.059
2.9ThrGlu: 2.9 ± 1.544
4.557ThrPhe: 4.557 ± 0.73
4.143ThrGly: 4.143 ± 1.452
1.243ThrHis: 1.243 ± 0.662
3.314ThrIle: 3.314 ± 1.765
4.143ThrLys: 4.143 ± 2.189
3.728ThrLeu: 3.728 ± 0.822
1.243ThrMet: 1.243 ± 0.672
2.9ThrAsn: 2.9 ± 1.156
0.829ThrPro: 0.829 ± 0.441
1.243ThrGln: 1.243 ± 0.672
1.243ThrArg: 1.243 ± 0.786
2.071ThrSer: 2.071 ± 0.799
0.829ThrThr: 0.829 ± 0.868
3.728ThrVal: 3.728 ± 1.403
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.314ValAla: 3.314 ± 2.16
1.657ValCys: 1.657 ± 2.295
4.143ValAsp: 4.143 ± 1.547
4.971ValGlu: 4.971 ± 3.145
1.243ValPhe: 1.243 ± 2.235
3.728ValGly: 3.728 ± 3.561
2.071ValHis: 2.071 ± 2.392
6.628ValIle: 6.628 ± 2.356
4.557ValLys: 4.557 ± 1.533
5.8ValLeu: 5.8 ± 2.844
0.829ValMet: 0.829 ± 0.441
5.385ValAsn: 5.385 ± 1.526
2.9ValPro: 2.9 ± 1.024
1.657ValGln: 1.657 ± 0.726
3.314ValArg: 3.314 ± 1.308
5.385ValSer: 5.385 ± 1.471
4.143ValThr: 4.143 ± 1.452
4.143ValVal: 4.143 ± 1.786
0.829ValTrp: 0.829 ± 0.688
1.657ValTyr: 1.657 ± 0.762
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.414TrpGlu: 0.414 ± 0.77
0.0TrpPhe: 0.0 ± 0.0
0.829TrpGly: 0.829 ± 0.441
0.0TrpHis: 0.0 ± 0.0
0.414TrpIle: 0.414 ± 0.77
0.829TrpLys: 0.829 ± 0.441
1.657TrpLeu: 1.657 ± 0.882
0.414TrpMet: 0.414 ± 0.221
0.414TrpAsn: 0.414 ± 0.77
0.0TrpPro: 0.0 ± 0.0
0.414TrpGln: 0.414 ± 0.77
0.829TrpArg: 0.829 ± 0.441
0.414TrpSer: 0.414 ± 0.221
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.071TyrAla: 2.071 ± 1.342
0.829TyrCys: 0.829 ± 1.244
1.243TyrAsp: 1.243 ± 0.672
2.9TyrGlu: 2.9 ± 1.024
0.0TyrPhe: 0.0 ± 0.0
0.829TyrGly: 0.829 ± 2.726
1.243TyrHis: 1.243 ± 0.786
3.728TyrIle: 3.728 ± 3.302
3.314TyrLys: 3.314 ± 1.183
3.314TyrLeu: 3.314 ± 1.523
0.414TyrMet: 0.414 ± 0.221
0.829TyrAsn: 0.829 ± 0.441
0.829TyrPro: 0.829 ± 0.868
1.243TyrGln: 1.243 ± 3.12
0.829TyrArg: 0.829 ± 0.441
2.9TyrSer: 2.9 ± 1.156
2.9TyrThr: 2.9 ± 1.21
4.143TyrVal: 4.143 ± 1.633
0.414TyrTrp: 0.414 ± 0.221
0.414TyrTyr: 0.414 ± 0.221
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2415 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski