Amino acid dipepetide frequency for Priestia koreensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.325AlaAla: 5.325 ± 0.106	0.609AlaCys: 0.609 ± 0.023	3.345AlaAsp: 3.345 ± 0.054	4.297AlaGlu: 4.297 ± 0.068	3.37AlaPhe: 3.37 ± 0.055	4.915AlaGly: 4.915 ± 0.108	1.494AlaHis: 1.494 ± 0.04	5.539AlaIle: 5.539 ± 0.073	4.882AlaLys: 4.882 ± 0.072	7.403AlaLeu: 7.403 ± 0.083	1.956AlaMet: 1.956 ± 0.043	2.709AlaAsn: 2.709 ± 0.045	2.199AlaPro: 2.199 ± 0.053	2.398AlaGln: 2.398 ± 0.047	2.656AlaArg: 2.656 ± 0.042	4.409AlaSer: 4.409 ± 0.06	3.89AlaThr: 3.89 ± 0.061	5.435AlaVal: 5.435 ± 0.078	0.584AlaTrp: 0.584 ± 0.023	2.49AlaTyr: 2.49 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.434CysAla: 0.434 ± 0.018	0.104CysCys: 0.104 ± 0.01	0.398CysAsp: 0.398 ± 0.018	0.487CysGlu: 0.487 ± 0.021	0.326CysPhe: 0.326 ± 0.017	0.62CysGly: 0.62 ± 0.024	0.208CysHis: 0.208 ± 0.015	0.512CysIle: 0.512 ± 0.021	0.337CysLys: 0.337 ± 0.018	0.672CysLeu: 0.672 ± 0.025	0.185CysMet: 0.185 ± 0.012	0.259CysAsn: 0.259 ± 0.014	0.329CysPro: 0.329 ± 0.018	0.246CysGln: 0.246 ± 0.015	0.274CysArg: 0.274 ± 0.015	0.5CysSer: 0.5 ± 0.021	0.429CysThr: 0.429 ± 0.02	0.433CysVal: 0.433 ± 0.019	0.088CysTrp: 0.088 ± 0.009	0.259CysTyr: 0.259 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.329AspAla: 3.329 ± 0.051	0.354AspCys: 0.354 ± 0.015	2.545AspAsp: 2.545 ± 0.05	4.463AspGlu: 4.463 ± 0.063	2.298AspPhe: 2.298 ± 0.05	3.355AspGly: 3.355 ± 0.054	1.392AspHis: 1.392 ± 0.034	3.755AspIle: 3.755 ± 0.052	2.802AspLys: 2.802 ± 0.047	5.106AspLeu: 5.106 ± 0.071	1.32AspMet: 1.32 ± 0.032	1.577AspAsn: 1.577 ± 0.04	1.98AspPro: 1.98 ± 0.047	2.406AspGln: 2.406 ± 0.047	2.291AspArg: 2.291 ± 0.044	2.376AspSer: 2.376 ± 0.048	2.375AspThr: 2.375 ± 0.049	4.334AspVal: 4.334 ± 0.059	0.596AspTrp: 0.596 ± 0.023	2.167AspTyr: 2.167 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	5.403GluAla: 5.403 ± 0.08	0.377GluCys: 0.377 ± 0.017	3.689GluAsp: 3.689 ± 0.063	6.974GluGlu: 6.974 ± 0.108	2.534GluPhe: 2.534 ± 0.047	4.355GluGly: 4.355 ± 0.058	1.701GluHis: 1.701 ± 0.043	4.841GluIle: 4.841 ± 0.078	6.265GluLys: 6.265 ± 0.083	6.892GluLeu: 6.892 ± 0.09	2.189GluMet: 2.189 ± 0.045	3.14GluAsn: 3.14 ± 0.052	1.791GluPro: 1.791 ± 0.038	3.567GluGln: 3.567 ± 0.062	3.681GluArg: 3.681 ± 0.063	3.421GluSer: 3.421 ± 0.056	3.695GluThr: 3.695 ± 0.061	5.107GluVal: 5.107 ± 0.064	0.8GluTrp: 0.8 ± 0.026	2.171GluTyr: 2.171 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	2.92PheAla: 2.92 ± 0.055	0.362PheCys: 0.362 ± 0.019	2.288PheAsp: 2.288 ± 0.045	2.574PheGlu: 2.574 ± 0.047	2.285PhePhe: 2.285 ± 0.049	3.195PheGly: 3.195 ± 0.059	1.108PheHis: 1.108 ± 0.028	3.49PheIle: 3.49 ± 0.06	2.345PheLys: 2.345 ± 0.046	4.727PheLeu: 4.727 ± 0.07	1.139PheMet: 1.139 ± 0.031	1.749PheAsn: 1.749 ± 0.04	1.616PhePro: 1.616 ± 0.038	1.772PheGln: 1.772 ± 0.04	1.483PheArg: 1.483 ± 0.036	3.331PheSer: 3.331 ± 0.049	2.584PheThr: 2.584 ± 0.052	3.346PheVal: 3.346 ± 0.057	0.495PheTrp: 0.495 ± 0.023	1.782PheTyr: 1.782 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	4.913GlyAla: 4.913 ± 0.106	0.606GlyCys: 0.606 ± 0.023	3.31GlyAsp: 3.31 ± 0.057	4.379GlyGlu: 4.379 ± 0.065	3.288GlyPhe: 3.288 ± 0.059	4.747GlyGly: 4.747 ± 0.087	1.43GlyHis: 1.43 ± 0.036	5.734GlyIle: 5.734 ± 0.079	4.893GlyLys: 4.893 ± 0.073	6.426GlyLeu: 6.426 ± 0.076	2.043GlyMet: 2.043 ± 0.046	2.601GlyAsn: 2.601 ± 0.054	1.706GlyPro: 1.706 ± 0.086	2.2GlyGln: 2.2 ± 0.043	2.542GlyArg: 2.542 ± 0.055	3.901GlySer: 3.901 ± 0.061	4.043GlyThr: 4.043 ± 0.088	5.339GlyVal: 5.339 ± 0.064	0.806GlyTrp: 0.806 ± 0.026	2.785GlyTyr: 2.785 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.444HisAla: 1.444 ± 0.033	0.201HisCys: 0.201 ± 0.015	1.253HisAsp: 1.253 ± 0.032	1.587HisGlu: 1.587 ± 0.044	1.119HisPhe: 1.119 ± 0.028	1.424HisGly: 1.424 ± 0.037	0.824HisHis: 0.824 ± 0.031	1.688HisIle: 1.688 ± 0.039	1.098HisLys: 1.098 ± 0.025	2.42HisLeu: 2.42 ± 0.045	0.609HisMet: 0.609 ± 0.022	0.812HisAsn: 0.812 ± 0.028	1.271HisPro: 1.271 ± 0.03	0.98HisGln: 0.98 ± 0.031	0.981HisArg: 0.981 ± 0.03	1.32HisSer: 1.32 ± 0.034	1.283HisThr: 1.283 ± 0.03	1.726HisVal: 1.726 ± 0.039	0.238HisTrp: 0.238 ± 0.015	1.059HisTyr: 1.059 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.572IleAla: 5.572 ± 0.081	0.609IleCys: 0.609 ± 0.021	3.948IleAsp: 3.948 ± 0.057	5.306IleGlu: 5.306 ± 0.077	3.047IlePhe: 3.047 ± 0.054	5.756IleGly: 5.756 ± 0.078	1.733IleHis: 1.733 ± 0.043	5.188IleIle: 5.188 ± 0.085	4.16IleLys: 4.16 ± 0.061	6.644IleLeu: 6.644 ± 0.076	1.772IleMet: 1.772 ± 0.035	2.852IleAsn: 2.852 ± 0.057	3.163IlePro: 3.163 ± 0.053	3.156IleGln: 3.156 ± 0.061	2.908IleArg: 2.908 ± 0.054	4.846IleSer: 4.846 ± 0.069	4.223IleThr: 4.223 ± 0.066	5.51IleVal: 5.51 ± 0.079	0.621IleTrp: 0.621 ± 0.022	2.329IleTyr: 2.329 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	4.759LysAla: 4.759 ± 0.068	0.286LysCys: 0.286 ± 0.015	3.706LysAsp: 3.706 ± 0.06	6.757LysGlu: 6.757 ± 0.089	1.804LysPhe: 1.804 ± 0.047	4.635LysGly: 4.635 ± 0.067	1.401LysHis: 1.401 ± 0.037	4.07LysIle: 4.07 ± 0.065	6.095LysLys: 6.095 ± 0.088	5.62LysLeu: 5.62 ± 0.08	2.195LysMet: 2.195 ± 0.042	3.041LysAsn: 3.041 ± 0.054	2.212LysPro: 2.212 ± 0.045	3.364LysGln: 3.364 ± 0.061	3.537LysArg: 3.537 ± 0.054	3.532LysSer: 3.532 ± 0.054	3.534LysThr: 3.534 ± 0.061	4.729LysVal: 4.729 ± 0.059	0.868LysTrp: 0.868 ± 0.03	1.987LysTyr: 1.987 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	7.288LeuAla: 7.288 ± 0.087	0.716LeuCys: 0.716 ± 0.028	4.693LeuAsp: 4.693 ± 0.063	6.241LeuGlu: 6.241 ± 0.087	4.786LeuPhe: 4.786 ± 0.078	6.396LeuGly: 6.396 ± 0.072	2.309LeuHis: 2.309 ± 0.046	6.737LeuIle: 6.737 ± 0.089	6.379LeuLys: 6.379 ± 0.083	10.533LeuLeu: 10.533 ± 0.123	2.502LeuMet: 2.502 ± 0.042	4.011LeuAsn: 4.011 ± 0.062	3.938LeuPro: 3.938 ± 0.057	4.137LeuGln: 4.137 ± 0.063	3.709LeuArg: 3.709 ± 0.059	7.145LeuSer: 7.145 ± 0.082	5.987LeuThr: 5.987 ± 0.101	6.715LeuVal: 6.715 ± 0.07	0.839LeuTrp: 0.839 ± 0.027	3.229LeuTyr: 3.229 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	1.907MetAla: 1.907 ± 0.041	0.16MetCys: 0.16 ± 0.011	1.393MetAsp: 1.393 ± 0.032	1.819MetGlu: 1.819 ± 0.042	1.007MetPhe: 1.007 ± 0.031	1.733MetGly: 1.733 ± 0.037	0.441MetHis: 0.441 ± 0.02	2.149MetIle: 2.149 ± 0.041	2.63MetLys: 2.63 ± 0.049	2.523MetLeu: 2.523 ± 0.05	0.983MetMet: 0.983 ± 0.032	1.657MetAsn: 1.657 ± 0.039	0.939MetPro: 0.939 ± 0.032	0.864MetGln: 0.864 ± 0.023	1.113MetArg: 1.113 ± 0.033	1.828MetSer: 1.828 ± 0.038	1.69MetThr: 1.69 ± 0.03	1.754MetVal: 1.754 ± 0.039	0.207MetTrp: 0.207 ± 0.011	0.797MetTyr: 0.797 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	2.658AsnAla: 2.658 ± 0.044	0.282AsnCys: 0.282 ± 0.015	2.249AsnAsp: 2.249 ± 0.047	3.375AsnGlu: 3.375 ± 0.052	1.492AsnPhe: 1.492 ± 0.04	3.141AsnGly: 3.141 ± 0.058	1.023AsnHis: 1.023 ± 0.028	2.912AsnIle: 2.912 ± 0.053	2.575AsnLys: 2.575 ± 0.053	3.536AsnLeu: 3.536 ± 0.053	1.13AsnMet: 1.13 ± 0.032	1.636AsnAsn: 1.636 ± 0.046	2.017AsnPro: 2.017 ± 0.059	1.877AsnGln: 1.877 ± 0.043	1.994AsnArg: 1.994 ± 0.042	2.071AsnSer: 2.071 ± 0.049	2.035AsnThr: 2.035 ± 0.057	3.224AsnVal: 3.224 ± 0.07	0.468AsnTrp: 0.468 ± 0.018	1.422AsnTyr: 1.422 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	2.278ProAla: 2.278 ± 0.047	0.203ProCys: 0.203 ± 0.014	1.864ProAsp: 1.864 ± 0.034	2.471ProGlu: 2.471 ± 0.047	2.017ProPhe: 2.017 ± 0.044	2.164ProGly: 2.164 ± 0.061	0.943ProHis: 0.943 ± 0.03	2.69ProIle: 2.69 ± 0.05	2.262ProLys: 2.262 ± 0.043	3.655ProLeu: 3.655 ± 0.058	0.765ProMet: 0.765 ± 0.023	1.672ProAsn: 1.672 ± 0.045	1.045ProPro: 1.045 ± 0.036	1.21ProGln: 1.21 ± 0.034	1.124ProArg: 1.124 ± 0.029	2.601ProSer: 2.601 ± 0.051	2.321ProThr: 2.321 ± 0.093	2.81ProVal: 2.81 ± 0.05	0.347ProTrp: 0.347 ± 0.018	1.496ProTyr: 1.496 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.961GlnAla: 2.961 ± 0.054	0.225GlnCys: 0.225 ± 0.013	1.856GlnAsp: 1.856 ± 0.039	3.026GlnGlu: 3.026 ± 0.059	1.61GlnPhe: 1.61 ± 0.036	2.4GlnGly: 2.4 ± 0.043	1.107GlnHis: 1.107 ± 0.027	2.465GlnIle: 2.465 ± 0.045	3.05GlnLys: 3.05 ± 0.051	4.246GlnLeu: 4.246 ± 0.06	1.143GlnMet: 1.143 ± 0.033	1.655GlnAsn: 1.655 ± 0.036	1.377GlnPro: 1.377 ± 0.045	2.116GlnGln: 2.116 ± 0.049	1.805GlnArg: 1.805 ± 0.043	2.381GlnSer: 2.381 ± 0.052	2.318GlnThr: 2.318 ± 0.045	2.495GlnVal: 2.495 ± 0.051	0.449GlnTrp: 0.449 ± 0.019	1.506GlnTyr: 1.506 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	2.584ArgAla: 2.584 ± 0.046	0.245ArgCys: 0.245 ± 0.014	2.15ArgAsp: 2.15 ± 0.046	3.166ArgGlu: 3.166 ± 0.052	1.931ArgPhe: 1.931 ± 0.042	2.314ArgGly: 2.314 ± 0.046	0.895ArgHis: 0.895 ± 0.027	3.085ArgIle: 3.085 ± 0.052	2.994ArgLys: 2.994 ± 0.053	4.089ArgLeu: 4.089 ± 0.061	1.277ArgMet: 1.277 ± 0.03	1.779ArgAsn: 1.779 ± 0.042	1.316ArgPro: 1.316 ± 0.032	1.615ArgGln: 1.615 ± 0.033	1.852ArgArg: 1.852 ± 0.039	2.485ArgSer: 2.485 ± 0.041	2.222ArgThr: 2.222 ± 0.042	2.893ArgVal: 2.893 ± 0.058	0.402ArgTrp: 0.402 ± 0.019	1.718ArgTyr: 1.718 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	3.934SerAla: 3.934 ± 0.053	0.39SerCys: 0.39 ± 0.02	2.873SerAsp: 2.873 ± 0.05	3.712SerGlu: 3.712 ± 0.053	3.458SerPhe: 3.458 ± 0.05	4.275SerGly: 4.275 ± 0.062	1.405SerHis: 1.405 ± 0.037	4.897SerIle: 4.897 ± 0.064	3.836SerLys: 3.836 ± 0.061	6.582SerLeu: 6.582 ± 0.086	1.806SerMet: 1.806 ± 0.041	2.445SerAsn: 2.445 ± 0.058	2.241SerPro: 2.241 ± 0.04	2.074SerGln: 2.074 ± 0.041	2.183SerArg: 2.183 ± 0.046	4.397SerSer: 4.397 ± 0.069	3.53SerThr: 3.53 ± 0.063	4.549SerVal: 4.549 ± 0.068	0.64SerTrp: 0.64 ± 0.023	2.509SerTyr: 2.509 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	3.889ThrAla: 3.889 ± 0.059	0.404ThrCys: 0.404 ± 0.017	2.743ThrAsp: 2.743 ± 0.051	3.434ThrGlu: 3.434 ± 0.056	2.877ThrPhe: 2.877 ± 0.067	4.011ThrGly: 4.011 ± 0.105	1.199ThrHis: 1.199 ± 0.033	4.72ThrIle: 4.72 ± 0.088	3.75ThrLys: 3.75 ± 0.063	5.546ThrLeu: 5.546 ± 0.075	1.362ThrMet: 1.362 ± 0.035	2.537ThrAsn: 2.537 ± 0.061	2.362ThrPro: 2.362 ± 0.04	1.64ThrGln: 1.64 ± 0.035	1.925ThrArg: 1.925 ± 0.043	3.605ThrSer: 3.605 ± 0.062	3.224ThrThr: 3.224 ± 0.107	4.316ThrVal: 4.316 ± 0.084	0.592ThrTrp: 0.592 ± 0.025	2.268ThrTyr: 2.268 ± 0.056	0.0ThrXaa: 0.0 ± 0.0
Val	5.516ValAla: 5.516 ± 0.085	0.6ValCys: 0.6 ± 0.027	3.828ValAsp: 3.828 ± 0.058	5.067ValGlu: 5.067 ± 0.067	3.083ValPhe: 3.083 ± 0.057	5.006ValGly: 5.006 ± 0.068	1.595ValHis: 1.595 ± 0.033	5.648ValIle: 5.648 ± 0.072	4.841ValLys: 4.841 ± 0.07	7.151ValLeu: 7.151 ± 0.079	1.965ValMet: 1.965 ± 0.04	2.988ValAsn: 2.988 ± 0.055	2.797ValPro: 2.797 ± 0.063	2.634ValGln: 2.634 ± 0.05	2.843ValArg: 2.843 ± 0.049	4.799ValSer: 4.799 ± 0.073	4.488ValThr: 4.488 ± 0.091	5.647ValVal: 5.647 ± 0.084	0.697ValTrp: 0.697 ± 0.023	2.438ValTyr: 2.438 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.588TrpAla: 0.588 ± 0.023	0.074TrpCys: 0.074 ± 0.007	0.521TrpAsp: 0.521 ± 0.022	0.642TrpGlu: 0.642 ± 0.026	0.556TrpPhe: 0.556 ± 0.024	0.703TrpGly: 0.703 ± 0.023	0.221TrpHis: 0.221 ± 0.013	0.831TrpIle: 0.831 ± 0.025	0.754TrpLys: 0.754 ± 0.025	1.124TrpLeu: 1.124 ± 0.036	0.334TrpMet: 0.334 ± 0.018	0.561TrpAsn: 0.561 ± 0.024	0.248TrpPro: 0.248 ± 0.014	0.357TrpGln: 0.357 ± 0.017	0.424TrpArg: 0.424 ± 0.019	0.688TrpSer: 0.688 ± 0.025	0.518TrpThr: 0.518 ± 0.021	0.652TrpVal: 0.652 ± 0.024	0.147TrpTrp: 0.147 ± 0.011	0.371TrpTyr: 0.371 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.205TyrAla: 2.205 ± 0.043	0.293TyrCys: 0.293 ± 0.014	2.167TyrAsp: 2.167 ± 0.057	2.815TyrGlu: 2.815 ± 0.048	1.704TyrPhe: 1.704 ± 0.039	2.544TyrGly: 2.544 ± 0.048	0.907TyrHis: 0.907 ± 0.027	2.392TyrIle: 2.392 ± 0.042	2.186TyrLys: 2.186 ± 0.041	3.396TyrLeu: 3.396 ± 0.057	0.922TyrMet: 0.922 ± 0.025	1.436TyrAsn: 1.436 ± 0.041	1.391TyrPro: 1.391 ± 0.036	1.58TyrGln: 1.58 ± 0.037	1.687TyrArg: 1.687 ± 0.045	2.099TyrSer: 2.099 ± 0.047	2.011TyrThr: 2.011 ± 0.048	2.618TyrVal: 2.618 ± 0.043	0.431TyrTrp: 0.431 ± 0.02	1.474TyrTyr: 1.474 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4402 proteins (1238965 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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