Amino acid dipepetide frequency for Wenzhouxiangella sp. 15181

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.269AlaAla: 12.269 ± 0.168	1.068AlaCys: 1.068 ± 0.036	6.756AlaAsp: 6.756 ± 0.099	8.232AlaGlu: 8.232 ± 0.123	3.581AlaPhe: 3.581 ± 0.071	10.271AlaGly: 10.271 ± 0.118	2.077AlaHis: 2.077 ± 0.049	5.132AlaIle: 5.132 ± 0.083	2.003AlaLys: 2.003 ± 0.063	11.968AlaLeu: 11.968 ± 0.146	2.839AlaMet: 2.839 ± 0.059	2.387AlaAsn: 2.387 ± 0.06	4.097AlaPro: 4.097 ± 0.068	3.137AlaGln: 3.137 ± 0.066	8.416AlaArg: 8.416 ± 0.107	5.61AlaSer: 5.61 ± 0.082	4.728AlaThr: 4.728 ± 0.076	8.038AlaVal: 8.038 ± 0.111	1.925AlaTrp: 1.925 ± 0.051	1.974AlaTyr: 1.974 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.781CysAla: 0.781 ± 0.029	0.11CysCys: 0.11 ± 0.011	0.493CysAsp: 0.493 ± 0.023	0.49CysGlu: 0.49 ± 0.025	0.297CysPhe: 0.297 ± 0.017	0.854CysGly: 0.854 ± 0.038	0.279CysHis: 0.279 ± 0.023	0.358CysIle: 0.358 ± 0.021	0.181CysLys: 0.181 ± 0.014	0.857CysLeu: 0.857 ± 0.029	0.179CysMet: 0.179 ± 0.016	0.212CysAsn: 0.212 ± 0.017	0.488CysPro: 0.488 ± 0.027	0.27CysGln: 0.27 ± 0.018	0.839CysArg: 0.839 ± 0.03	0.504CysSer: 0.504 ± 0.023	0.383CysThr: 0.383 ± 0.022	0.543CysVal: 0.543 ± 0.026	0.121CysTrp: 0.121 ± 0.012	0.208CysTyr: 0.208 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.048AspAla: 6.048 ± 0.088	0.608AspCys: 0.608 ± 0.03	4.241AspAsp: 4.241 ± 0.085	5.272AspGlu: 5.272 ± 0.083	2.527AspPhe: 2.527 ± 0.053	5.766AspGly: 5.766 ± 0.108	1.507AspHis: 1.507 ± 0.042	2.973AspIle: 2.973 ± 0.062	1.488AspLys: 1.488 ± 0.047	6.262AspLeu: 6.262 ± 0.088	1.418AspMet: 1.418 ± 0.035	1.674AspAsn: 1.674 ± 0.048	3.48AspPro: 3.48 ± 0.069	2.136AspGln: 2.136 ± 0.046	5.265AspArg: 5.265 ± 0.088	3.431AspSer: 3.431 ± 0.068	2.765AspThr: 2.765 ± 0.052	3.895AspVal: 3.895 ± 0.065	1.368AspTrp: 1.368 ± 0.043	1.782AspTyr: 1.782 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	8.062GluAla: 8.062 ± 0.132	0.453GluCys: 0.453 ± 0.022	3.894GluAsp: 3.894 ± 0.067	4.6GluGlu: 4.6 ± 0.094	2.253GluPhe: 2.253 ± 0.048	5.009GluGly: 5.009 ± 0.084	1.896GluHis: 1.896 ± 0.045	3.628GluIle: 3.628 ± 0.061	2.156GluLys: 2.156 ± 0.059	8.186GluLeu: 8.186 ± 0.092	1.665GluMet: 1.665 ± 0.042	1.883GluAsn: 1.883 ± 0.049	3.586GluPro: 3.586 ± 0.07	3.304GluGln: 3.304 ± 0.071	6.994GluArg: 6.994 ± 0.103	4.23GluSer: 4.23 ± 0.076	3.938GluThr: 3.938 ± 0.07	4.623GluVal: 4.623 ± 0.076	0.968GluTrp: 0.968 ± 0.036	1.436GluTyr: 1.436 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.601PheAla: 3.601 ± 0.068	0.329PheCys: 0.329 ± 0.021	2.853PheAsp: 2.853 ± 0.06	2.793PheGlu: 2.793 ± 0.059	1.354PhePhe: 1.354 ± 0.048	3.38PheGly: 3.38 ± 0.067	0.828PheHis: 0.828 ± 0.033	1.618PheIle: 1.618 ± 0.044	0.786PheLys: 0.786 ± 0.034	3.238PheLeu: 3.238 ± 0.066	0.731PheMet: 0.731 ± 0.031	1.077PheAsn: 1.077 ± 0.033	1.508PhePro: 1.508 ± 0.042	1.047PheGln: 1.047 ± 0.031	2.453PheArg: 2.453 ± 0.056	2.404PheSer: 2.404 ± 0.053	1.748PheThr: 1.748 ± 0.043	2.609PheVal: 2.609 ± 0.052	0.548PheTrp: 0.548 ± 0.027	0.846PheTyr: 0.846 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	7.143GlyAla: 7.143 ± 0.099	0.875GlyCys: 0.875 ± 0.032	5.036GlyAsp: 5.036 ± 0.081	6.403GlyGlu: 6.403 ± 0.086	3.32GlyPhe: 3.32 ± 0.061	6.917GlyGly: 6.917 ± 0.112	2.149GlyHis: 2.149 ± 0.047	4.328GlyIle: 4.328 ± 0.08	2.51GlyLys: 2.51 ± 0.056	8.947GlyLeu: 8.947 ± 0.112	2.331GlyMet: 2.331 ± 0.055	2.312GlyAsn: 2.312 ± 0.062	3.246GlyPro: 3.246 ± 0.07	3.152GlyGln: 3.152 ± 0.058	6.623GlyArg: 6.623 ± 0.097	4.982GlySer: 4.982 ± 0.098	4.096GlyThr: 4.096 ± 0.077	5.756GlyVal: 5.756 ± 0.094	1.563GlyTrp: 1.563 ± 0.043	2.169GlyTyr: 2.169 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	2.392HisAla: 2.392 ± 0.06	0.258HisCys: 0.258 ± 0.017	1.455HisAsp: 1.455 ± 0.043	1.505HisGlu: 1.505 ± 0.038	1.008HisPhe: 1.008 ± 0.036	2.031HisGly: 2.031 ± 0.043	0.696HisHis: 0.696 ± 0.031	0.97HisIle: 0.97 ± 0.036	0.506HisLys: 0.506 ± 0.022	2.389HisLeu: 2.389 ± 0.052	0.43HisMet: 0.43 ± 0.022	0.523HisAsn: 0.523 ± 0.026	1.517HisPro: 1.517 ± 0.044	0.735HisGln: 0.735 ± 0.031	1.939HisArg: 1.939 ± 0.044	1.13HisSer: 1.13 ± 0.035	0.879HisThr: 0.879 ± 0.031	1.605HisVal: 1.605 ± 0.04	0.448HisTrp: 0.448 ± 0.022	0.717HisTyr: 0.717 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.416IleAla: 5.416 ± 0.087	0.401IleCys: 0.401 ± 0.021	4.068IleAsp: 4.068 ± 0.073	4.41IleGlu: 4.41 ± 0.072	1.417IlePhe: 1.417 ± 0.04	4.508IleGly: 4.508 ± 0.08	1.145IleHis: 1.145 ± 0.035	2.139IleIle: 2.139 ± 0.05	1.158IleLys: 1.158 ± 0.045	4.259IleLeu: 4.259 ± 0.08	0.868IleMet: 0.868 ± 0.029	1.57IleAsn: 1.57 ± 0.04	2.155IlePro: 2.155 ± 0.05	1.391IleGln: 1.391 ± 0.039	3.564IleArg: 3.564 ± 0.063	2.691IleSer: 2.691 ± 0.067	2.41IleThr: 2.41 ± 0.056	3.698IleVal: 3.698 ± 0.062	0.583IleTrp: 0.583 ± 0.028	1.016IleTyr: 1.016 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	2.658LysAla: 2.658 ± 0.067	0.163LysCys: 0.163 ± 0.013	1.242LysAsp: 1.242 ± 0.038	1.319LysGlu: 1.319 ± 0.046	0.67LysPhe: 0.67 ± 0.028	1.756LysGly: 1.756 ± 0.051	0.637LysHis: 0.637 ± 0.025	1.09LysIle: 1.09 ± 0.041	1.053LysLys: 1.053 ± 0.051	2.794LysLeu: 2.794 ± 0.057	0.56LysMet: 0.56 ± 0.025	0.623LysAsn: 0.623 ± 0.025	1.551LysPro: 1.551 ± 0.047	1.058LysGln: 1.058 ± 0.03	2.237LysArg: 2.237 ± 0.064	1.411LysSer: 1.411 ± 0.037	1.288LysThr: 1.288 ± 0.043	1.798LysVal: 1.798 ± 0.052	0.269LysTrp: 0.269 ± 0.016	0.489LysTyr: 0.489 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	13.686LeuAla: 13.686 ± 0.176	0.862LeuCys: 0.862 ± 0.033	7.419LeuAsp: 7.419 ± 0.096	8.067LeuGlu: 8.067 ± 0.107	3.756LeuPhe: 3.756 ± 0.079	8.45LeuGly: 8.45 ± 0.119	2.112LeuHis: 2.112 ± 0.052	5.335LeuIle: 5.335 ± 0.079	2.965LeuLys: 2.965 ± 0.066	10.846LeuLeu: 10.846 ± 0.15	2.407LeuMet: 2.407 ± 0.053	2.597LeuAsn: 2.597 ± 0.058	5.499LeuPro: 5.499 ± 0.095	2.89LeuGln: 2.89 ± 0.064	7.0LeuArg: 7.0 ± 0.091	6.129LeuSer: 6.129 ± 0.09	5.059LeuThr: 5.059 ± 0.068	8.223LeuVal: 8.223 ± 0.101	1.373LeuTrp: 1.373 ± 0.047	2.039LeuTyr: 2.039 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.781MetAla: 2.781 ± 0.061	0.124MetCys: 0.124 ± 0.012	1.243MetAsp: 1.243 ± 0.041	1.23MetGlu: 1.23 ± 0.041	0.663MetPhe: 0.663 ± 0.028	1.637MetGly: 1.637 ± 0.048	0.514MetHis: 0.514 ± 0.022	1.221MetIle: 1.221 ± 0.044	0.835MetLys: 0.835 ± 0.027	2.613MetLeu: 2.613 ± 0.061	0.514MetMet: 0.514 ± 0.024	0.827MetAsn: 0.827 ± 0.025	1.345MetPro: 1.345 ± 0.041	0.847MetGln: 0.847 ± 0.03	1.715MetArg: 1.715 ± 0.043	1.551MetSer: 1.551 ± 0.042	1.421MetThr: 1.421 ± 0.04	1.6MetVal: 1.6 ± 0.042	0.206MetTrp: 0.206 ± 0.016	0.315MetTyr: 0.315 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.744AsnAla: 2.744 ± 0.055	0.233AsnCys: 0.233 ± 0.014	1.502AsnAsp: 1.502 ± 0.039	1.618AsnGlu: 1.618 ± 0.044	0.922AsnPhe: 0.922 ± 0.037	2.123AsnGly: 2.123 ± 0.052	0.624AsnHis: 0.624 ± 0.021	1.317AsnIle: 1.317 ± 0.042	0.561AsnLys: 0.561 ± 0.026	2.86AsnLeu: 2.86 ± 0.055	0.542AsnMet: 0.542 ± 0.022	0.747AsnAsn: 0.747 ± 0.03	1.711AsnPro: 1.711 ± 0.045	0.931AsnGln: 0.931 ± 0.033	2.201AsnArg: 2.201 ± 0.051	1.28AsnSer: 1.28 ± 0.044	1.235AsnThr: 1.235 ± 0.039	1.812AsnVal: 1.812 ± 0.053	0.449AsnTrp: 0.449 ± 0.023	0.679AsnTyr: 0.679 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	5.17ProAla: 5.17 ± 0.091	0.332ProCys: 0.332 ± 0.02	4.197ProAsp: 4.197 ± 0.065	4.884ProGlu: 4.884 ± 0.086	1.66ProPhe: 1.66 ± 0.043	4.836ProGly: 4.836 ± 0.083	0.995ProHis: 0.995 ± 0.032	2.064ProIle: 2.064 ± 0.049	1.074ProLys: 1.074 ± 0.035	4.651ProLeu: 4.651 ± 0.072	1.121ProMet: 1.121 ± 0.032	1.16ProAsn: 1.16 ± 0.038	2.345ProPro: 2.345 ± 0.054	1.408ProGln: 1.408 ± 0.034	2.886ProArg: 2.886 ± 0.06	2.35ProSer: 2.35 ± 0.046	2.104ProThr: 2.104 ± 0.053	4.242ProVal: 4.242 ± 0.056	0.776ProTrp: 0.776 ± 0.029	0.939ProTyr: 0.939 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.427GlnAla: 4.427 ± 0.084	0.22GlnCys: 0.22 ± 0.015	1.536GlnAsp: 1.536 ± 0.042	1.761GlnGlu: 1.761 ± 0.045	1.222GlnPhe: 1.222 ± 0.04	2.346GlnGly: 2.346 ± 0.049	0.752GlnHis: 0.752 ± 0.028	1.549GlnIle: 1.549 ± 0.043	0.809GlnLys: 0.809 ± 0.037	3.63GlnLeu: 3.63 ± 0.068	0.749GlnMet: 0.749 ± 0.026	0.702GlnAsn: 0.702 ± 0.028	2.035GlnPro: 2.035 ± 0.047	1.507GlnGln: 1.507 ± 0.045	3.088GlnArg: 3.088 ± 0.066	1.967GlnSer: 1.967 ± 0.047	1.569GlnThr: 1.569 ± 0.048	2.715GlnVal: 2.715 ± 0.055	0.6GlnTrp: 0.6 ± 0.025	0.731GlnTyr: 0.731 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	7.184ArgAla: 7.184 ± 0.097	0.588ArgCys: 0.588 ± 0.026	4.515ArgAsp: 4.515 ± 0.076	5.797ArgGlu: 5.797 ± 0.089	3.253ArgPhe: 3.253 ± 0.059	4.92ArgGly: 4.92 ± 0.078	2.115ArgHis: 2.115 ± 0.052	4.38ArgIle: 4.38 ± 0.073	2.204ArgLys: 2.204 ± 0.047	9.433ArgLeu: 9.433 ± 0.128	1.93ArgMet: 1.93 ± 0.043	2.114ArgAsn: 2.114 ± 0.053	3.691ArgPro: 3.691 ± 0.067	3.296ArgGln: 3.296 ± 0.063	6.747ArgArg: 6.747 ± 0.124	4.179ArgSer: 4.179 ± 0.08	3.14ArgThr: 3.14 ± 0.069	5.622ArgVal: 5.622 ± 0.093	1.307ArgTrp: 1.307 ± 0.042	2.093ArgTyr: 2.093 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.682SerAla: 5.682 ± 0.081	0.394SerCys: 0.394 ± 0.024	3.632SerAsp: 3.632 ± 0.071	4.017SerGlu: 4.017 ± 0.07	1.974SerPhe: 1.974 ± 0.047	6.034SerGly: 6.034 ± 0.102	1.247SerHis: 1.247 ± 0.034	2.611SerIle: 2.611 ± 0.055	1.221SerLys: 1.221 ± 0.039	5.87SerLeu: 5.87 ± 0.091	1.391SerMet: 1.391 ± 0.039	1.459SerAsn: 1.459 ± 0.044	2.762SerPro: 2.762 ± 0.06	1.744SerGln: 1.744 ± 0.041	4.292SerArg: 4.292 ± 0.071	3.165SerSer: 3.165 ± 0.071	2.575SerThr: 2.575 ± 0.06	3.93SerVal: 3.93 ± 0.077	0.799SerTrp: 0.799 ± 0.032	1.184SerTyr: 1.184 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.182ThrAla: 5.182 ± 0.077	0.423ThrCys: 0.423 ± 0.023	2.963ThrAsp: 2.963 ± 0.062	2.954ThrGlu: 2.954 ± 0.054	1.622ThrPhe: 1.622 ± 0.043	4.814ThrGly: 4.814 ± 0.085	0.999ThrHis: 0.999 ± 0.028	2.409ThrIle: 2.409 ± 0.053	0.765ThrLys: 0.765 ± 0.029	5.354ThrLeu: 5.354 ± 0.079	0.931ThrMet: 0.931 ± 0.033	1.13ThrAsn: 1.13 ± 0.037	2.612ThrPro: 2.612 ± 0.051	1.304ThrGln: 1.304 ± 0.035	3.48ThrArg: 3.48 ± 0.062	2.434ThrSer: 2.434 ± 0.049	2.439ThrThr: 2.439 ± 0.06	3.954ThrVal: 3.954 ± 0.063	0.795ThrTrp: 0.795 ± 0.03	0.916ThrTyr: 0.916 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	7.976ValAla: 7.976 ± 0.097	0.618ValCys: 0.618 ± 0.022	4.959ValAsp: 4.959 ± 0.073	5.303ValGlu: 5.303 ± 0.084	2.641ValPhe: 2.641 ± 0.065	5.399ValGly: 5.399 ± 0.075	1.591ValHis: 1.591 ± 0.043	4.055ValIle: 4.055 ± 0.081	1.542ValLys: 1.542 ± 0.043	7.678ValLeu: 7.678 ± 0.11	1.757ValMet: 1.757 ± 0.043	2.022ValAsn: 2.022 ± 0.05	3.52ValPro: 3.52 ± 0.06	2.028ValGln: 2.028 ± 0.043	5.056ValArg: 5.056 ± 0.073	4.376ValSer: 4.376 ± 0.08	3.948ValThr: 3.948 ± 0.058	5.897ValVal: 5.897 ± 0.102	1.008ValTrp: 1.008 ± 0.034	1.6ValTyr: 1.6 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.236TrpAla: 1.236 ± 0.035	0.158TrpCys: 0.158 ± 0.012	0.665TrpAsp: 0.665 ± 0.027	0.735TrpGlu: 0.735 ± 0.028	0.673TrpPhe: 0.673 ± 0.031	0.873TrpGly: 0.873 ± 0.034	0.445TrpHis: 0.445 ± 0.023	0.833TrpIle: 0.833 ± 0.029	0.374TrpLys: 0.374 ± 0.022	2.466TrpLeu: 2.466 ± 0.058	0.393TrpMet: 0.393 ± 0.022	0.43TrpAsn: 0.43 ± 0.02	0.87TrpPro: 0.87 ± 0.031	0.893TrpGln: 0.893 ± 0.031	1.472TrpArg: 1.472 ± 0.046	0.912TrpSer: 0.912 ± 0.035	0.716TrpThr: 0.716 ± 0.033	0.994TrpVal: 0.994 ± 0.033	0.317TrpTrp: 0.317 ± 0.018	0.401TrpTyr: 0.401 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.071TyrAla: 2.071 ± 0.047	0.229TyrCys: 0.229 ± 0.013	1.238TyrAsp: 1.238 ± 0.04	1.373TyrGlu: 1.373 ± 0.043	0.937TyrPhe: 0.937 ± 0.031	1.935TyrGly: 1.935 ± 0.047	0.525TyrHis: 0.525 ± 0.022	0.859TyrIle: 0.859 ± 0.031	0.476TyrLys: 0.476 ± 0.024	2.41TyrLeu: 2.41 ± 0.051	0.445TyrMet: 0.445 ± 0.02	0.643TyrAsn: 0.643 ± 0.026	1.176TyrPro: 1.176 ± 0.037	0.838TyrGln: 0.838 ± 0.031	2.244TyrArg: 2.244 ± 0.051	1.249TyrSer: 1.249 ± 0.043	1.035TyrThr: 1.035 ± 0.034	1.418TyrVal: 1.418 ± 0.039	0.432TyrTrp: 0.432 ± 0.025	0.645TyrTyr: 0.645 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2733 proteins (936914 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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