Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida; Candida albicans

Average proteome isoelectric point is 6.37

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6036 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1D8PJY0|A0A1D8PJY0_CANAL DUF2235 domain-containing protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=orf19.5894 PE=4 SV=1
MM1 pKa = 7.63DD2 pKa = 5.41HH3 pKa = 7.04SLTSYY8 pKa = 10.72LLSKK12 pKa = 9.51ITTNLEE18 pKa = 3.71CSICSEE24 pKa = 3.9IMIIPMTIEE33 pKa = 4.64CGHH36 pKa = 5.96SFCYY40 pKa = 10.36DD41 pKa = 4.35CIYY44 pKa = 10.9QWFSNKK50 pKa = 9.02INCPTCRR57 pKa = 11.84HH58 pKa = 6.5DD59 pKa = 5.11IEE61 pKa = 4.96NKK63 pKa = 9.79PILNIHH69 pKa = 6.66LKK71 pKa = 9.71EE72 pKa = 3.93ICHH75 pKa = 6.52KK76 pKa = 9.9IIEE79 pKa = 4.59SIIEE83 pKa = 3.97NTSNGDD89 pKa = 3.12GDD91 pKa = 4.3GDD93 pKa = 4.01GDD95 pKa = 4.21SGGVDD100 pKa = 2.66HH101 pKa = 7.39LMNRR105 pKa = 11.84KK106 pKa = 9.27LEE108 pKa = 4.06CLKK111 pKa = 10.24TYY113 pKa = 10.97NLDD116 pKa = 3.68VKK118 pKa = 10.68NKK120 pKa = 10.52SIFGDD125 pKa = 4.04LFNNTVTTLIDD136 pKa = 3.82CSDD139 pKa = 3.21GVARR143 pKa = 11.84CGNCHH148 pKa = 6.0WEE150 pKa = 4.02VHH152 pKa = 5.82GSICSHH158 pKa = 6.62CGTRR162 pKa = 11.84FRR164 pKa = 11.84RR165 pKa = 11.84STRR168 pKa = 11.84NINGEE173 pKa = 4.05SEE175 pKa = 4.02EE176 pKa = 5.32DD177 pKa = 3.45EE178 pKa = 5.82DD179 pKa = 6.24EE180 pKa = 5.29EE181 pKa = 6.97DD182 pKa = 6.23DD183 pKa = 6.53DD184 pKa = 7.44DD185 pKa = 7.73DD186 pKa = 7.61DD187 pKa = 6.83DD188 pKa = 7.32DD189 pKa = 4.85EE190 pKa = 5.87DD191 pKa = 4.32AFEE194 pKa = 4.76DD195 pKa = 4.11VVAGFRR201 pKa = 11.84QSVEE205 pKa = 3.6INEE208 pKa = 4.11YY209 pKa = 11.04DD210 pKa = 3.87SDD212 pKa = 4.62DD213 pKa = 3.99SFIDD217 pKa = 3.27SRR219 pKa = 11.84TANEE223 pKa = 4.25IPVGTDD229 pKa = 2.62SDD231 pKa = 4.54SEE233 pKa = 4.03ISIHH237 pKa = 7.21INANNNNNNNGNVYY251 pKa = 10.78DD252 pKa = 4.27NEE254 pKa = 4.57SNEE257 pKa = 4.19NNNTDD262 pKa = 3.96DD263 pKa = 5.83DD264 pKa = 4.8DD265 pKa = 6.4DD266 pKa = 4.68EE267 pKa = 5.13EE268 pKa = 4.57EE269 pKa = 4.41EE270 pKa = 4.64EE271 pKa = 4.93YY272 pKa = 11.42GDD274 pKa = 3.34NHH276 pKa = 6.98LGHH279 pKa = 6.65TEE281 pKa = 3.96SFGNNSAIHH290 pKa = 6.85DD291 pKa = 4.01DD292 pKa = 3.05WHH294 pKa = 7.73GFEE297 pKa = 5.01SATSSVIDD305 pKa = 3.96RR306 pKa = 11.84AFSDD310 pKa = 3.59DD311 pKa = 4.18DD312 pKa = 3.9EE313 pKa = 5.08EE314 pKa = 4.7EE315 pKa = 4.51EE316 pKa = 4.48EE317 pKa = 4.4DD318 pKa = 4.19VSIQRR323 pKa = 11.84SMNSPYY329 pKa = 11.01NNDD332 pKa = 3.76SIEE335 pKa = 4.23LSSSEE340 pKa = 4.38HH341 pKa = 6.08EE342 pKa = 4.7NIIQLSGDD350 pKa = 4.25DD351 pKa = 4.74EE352 pKa = 6.02DD353 pKa = 5.46DD354 pKa = 3.73SYY356 pKa = 12.14YY357 pKa = 11.03DD358 pKa = 3.94SEE360 pKa = 5.12DD361 pKa = 2.97IRR363 pKa = 11.84DD364 pKa = 3.81AMEE367 pKa = 4.06EE368 pKa = 3.85MDD370 pKa = 5.67NFNIDD375 pKa = 3.21NTDD378 pKa = 3.27YY379 pKa = 11.64SNEE382 pKa = 3.98EE383 pKa = 3.6EE384 pKa = 4.51DD385 pKa = 5.53DD386 pKa = 4.01VVEE389 pKa = 4.2LSDD392 pKa = 3.75YY393 pKa = 11.39NSYY396 pKa = 10.21SDD398 pKa = 5.17NMISDD403 pKa = 3.9VDD405 pKa = 4.15NDD407 pKa = 5.42DD408 pKa = 6.21DD409 pKa = 7.19DD410 pKa = 7.64DD411 pKa = 7.54DD412 pKa = 7.15DD413 pKa = 5.82DD414 pKa = 4.47GWWW417 pKa = 3.15

Molecular weight: 47.32 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1D8PN64|A0A1D8PN64_CANAL Aa_trans domain-containing protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=orf19.4142 PE=3 SV=1
MM1 pKa = 7.52FSNILRR7 pKa = 11.84QSSRR11 pKa = 11.84GLINFTSVSSRR22 pKa = 11.84PLGVPAFGMNPLITSSPLQSVVGLMQQRR50 pKa = 11.84FKK52 pKa = 11.5SRR54 pKa = 11.84GNTYY58 pKa = 10.2QPSTRR63 pKa = 11.84KK64 pKa = 9.59RR65 pKa = 11.84KK66 pKa = 9.61RR67 pKa = 11.84KK68 pKa = 9.79LGFLARR74 pKa = 11.84LRR76 pKa = 11.84SIGGRR81 pKa = 11.84KK82 pKa = 8.48ILEE85 pKa = 3.7RR86 pKa = 11.84RR87 pKa = 11.84RR88 pKa = 11.84AKK90 pKa = 10.52GRR92 pKa = 11.84WFLSHH97 pKa = 7.05

Molecular weight: 11.08 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6035

1

6036

2982981

31

5035

494.2

55.82

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.049 ± 0.024

1.067 ± 0.01

5.905 ± 0.025

6.467 ± 0.033

4.396 ± 0.02

5.079 ± 0.025

2.09 ± 0.012

7.114 ± 0.027

7.348 ± 0.033

9.209 ± 0.037

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.782 ± 0.009

6.691 ± 0.032

4.473 ± 0.024

4.493 ± 0.031

3.763 ± 0.021

8.976 ± 0.046

6.146 ± 0.031

5.429 ± 0.024

0.969 ± 0.01

3.55 ± 0.018
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski