Amino acid dipepetide frequency for Absidia repens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.819AlaAla: 5.819 ± 0.054	0.919AlaCys: 0.919 ± 0.013	3.315AlaAsp: 3.315 ± 0.023	3.064AlaGlu: 3.064 ± 0.028	2.546AlaPhe: 2.546 ± 0.023	3.412AlaGly: 3.412 ± 0.028	1.527AlaHis: 1.527 ± 0.017	3.969AlaIle: 3.969 ± 0.029	3.703AlaLys: 3.703 ± 0.035	6.41AlaLeu: 6.41 ± 0.036	1.9AlaMet: 1.9 ± 0.017	2.917AlaAsn: 2.917 ± 0.023	3.112AlaPro: 3.112 ± 0.027	2.629AlaGln: 2.629 ± 0.024	2.882AlaArg: 2.882 ± 0.023	5.982AlaSer: 5.982 ± 0.039	5.313AlaThr: 5.313 ± 0.037	3.843AlaVal: 3.843 ± 0.028	0.698AlaTrp: 0.698 ± 0.011	1.95AlaTyr: 1.95 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.782CysAla: 0.782 ± 0.012	0.308CysCys: 0.308 ± 0.008	0.774CysAsp: 0.774 ± 0.012	0.577CysGlu: 0.577 ± 0.01	0.652CysPhe: 0.652 ± 0.011	0.939CysGly: 0.939 ± 0.016	0.496CysHis: 0.496 ± 0.009	0.894CysIle: 0.894 ± 0.013	0.615CysLys: 0.615 ± 0.009	1.482CysLeu: 1.482 ± 0.019	0.348CysMet: 0.348 ± 0.008	0.573CysAsn: 0.573 ± 0.01	0.694CysPro: 0.694 ± 0.013	0.659CysGln: 0.659 ± 0.011	0.737CysArg: 0.737 ± 0.011	1.018CysSer: 1.018 ± 0.014	0.764CysThr: 0.764 ± 0.012	0.876CysVal: 0.876 ± 0.014	0.181CysTrp: 0.181 ± 0.005	0.505CysTyr: 0.505 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.798AspAla: 3.798 ± 0.025	0.69AspCys: 0.69 ± 0.01	6.58AspAsp: 6.58 ± 0.071	4.142AspGlu: 4.142 ± 0.031	2.18AspPhe: 2.18 ± 0.024	3.518AspGly: 3.518 ± 0.028	1.816AspHis: 1.816 ± 0.021	3.831AspIle: 3.831 ± 0.03	2.906AspLys: 2.906 ± 0.023	5.277AspLeu: 5.277 ± 0.036	1.691AspMet: 1.691 ± 0.017	2.996AspAsn: 2.996 ± 0.023	2.66AspPro: 2.66 ± 0.022	2.88AspGln: 2.88 ± 0.021	2.705AspArg: 2.705 ± 0.022	4.222AspSer: 4.222 ± 0.028	3.764AspThr: 3.764 ± 0.024	3.363AspVal: 3.363 ± 0.023	0.756AspTrp: 0.756 ± 0.012	2.134AspTyr: 2.134 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	3.411GluAla: 3.411 ± 0.031	0.631GluCys: 0.631 ± 0.011	3.486GluAsp: 3.486 ± 0.031	3.988GluGlu: 3.988 ± 0.042	1.783GluPhe: 1.783 ± 0.017	2.335GluGly: 2.335 ± 0.022	1.466GluHis: 1.466 ± 0.017	2.765GluIle: 2.765 ± 0.02	3.684GluLys: 3.684 ± 0.034	4.835GluLeu: 4.835 ± 0.033	1.408GluMet: 1.408 ± 0.015	2.716GluAsn: 2.716 ± 0.023	1.862GluPro: 1.862 ± 0.019	3.098GluGln: 3.098 ± 0.029	2.925GluArg: 2.925 ± 0.023	3.555GluSer: 3.555 ± 0.026	3.163GluThr: 3.163 ± 0.024	2.45GluVal: 2.45 ± 0.032	0.672GluTrp: 0.672 ± 0.01	1.725GluTyr: 1.725 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.469PheAla: 2.469 ± 0.024	0.664PheCys: 0.664 ± 0.013	2.53PheAsp: 2.53 ± 0.024	1.984PheGlu: 1.984 ± 0.021	1.852PhePhe: 1.852 ± 0.023	2.661PheGly: 2.661 ± 0.028	0.945PheHis: 0.945 ± 0.014	2.245PheIle: 2.245 ± 0.025	1.776PheLys: 1.776 ± 0.019	3.552PheLeu: 3.552 ± 0.031	1.044PheMet: 1.044 ± 0.013	1.606PheAsn: 1.606 ± 0.016	1.507PhePro: 1.507 ± 0.019	1.415PheGln: 1.415 ± 0.016	1.55PheArg: 1.55 ± 0.017	2.997PheSer: 2.997 ± 0.024	2.211PheThr: 2.211 ± 0.02	2.447PheVal: 2.447 ± 0.022	0.548PheTrp: 0.548 ± 0.011	1.495PheTyr: 1.495 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	3.41GlyAla: 3.41 ± 0.03	0.808GlyCys: 0.808 ± 0.013	3.281GlyAsp: 3.281 ± 0.024	2.391GlyGlu: 2.391 ± 0.022	2.312GlyPhe: 2.312 ± 0.024	4.217GlyGly: 4.217 ± 0.041	1.528GlyHis: 1.528 ± 0.016	3.183GlyIle: 3.183 ± 0.026	3.117GlyLys: 3.117 ± 0.024	4.77GlyLeu: 4.77 ± 0.034	1.411GlyMet: 1.411 ± 0.016	2.716GlyAsn: 2.716 ± 0.023	1.856GlyPro: 1.856 ± 0.02	2.239GlyGln: 2.239 ± 0.021	2.598GlyArg: 2.598 ± 0.027	4.447GlySer: 4.447 ± 0.03	3.305GlyThr: 3.305 ± 0.026	3.352GlyVal: 3.352 ± 0.028	0.759GlyTrp: 0.759 ± 0.013	2.007GlyTyr: 2.007 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	1.621HisAla: 1.621 ± 0.015	0.488HisCys: 0.488 ± 0.01	1.705HisAsp: 1.705 ± 0.019	1.272HisGlu: 1.272 ± 0.016	1.067HisPhe: 1.067 ± 0.013	1.668HisGly: 1.668 ± 0.017	2.107HisHis: 2.107 ± 0.035	1.539HisIle: 1.539 ± 0.017	1.095HisLys: 1.095 ± 0.015	2.885HisLeu: 2.885 ± 0.025	0.64HisMet: 0.64 ± 0.01	1.107HisAsn: 1.107 ± 0.015	1.781HisPro: 1.781 ± 0.021	2.174HisGln: 2.174 ± 0.025	1.688HisArg: 1.688 ± 0.017	2.339HisSer: 2.339 ± 0.026	1.63HisThr: 1.63 ± 0.017	1.568HisVal: 1.568 ± 0.016	0.358HisTrp: 0.358 ± 0.008	1.138HisTyr: 1.138 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	3.508IleAla: 3.508 ± 0.029	0.898IleCys: 0.898 ± 0.013	3.314IleAsp: 3.314 ± 0.023	2.722IleGlu: 2.722 ± 0.023	2.092IlePhe: 2.092 ± 0.023	3.047IleGly: 3.047 ± 0.027	1.682IleHis: 1.682 ± 0.016	3.077IleIle: 3.077 ± 0.028	3.162IleLys: 3.162 ± 0.024	5.241IleLeu: 5.241 ± 0.034	1.371IleMet: 1.371 ± 0.016	2.58IleAsn: 2.58 ± 0.018	3.064IlePro: 3.064 ± 0.025	2.752IleGln: 2.752 ± 0.021	2.787IleArg: 2.787 ± 0.021	4.423IleSer: 4.423 ± 0.029	3.288IleThr: 3.288 ± 0.026	3.231IleVal: 3.231 ± 0.022	0.644IleTrp: 0.644 ± 0.011	1.982IleTyr: 1.982 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	3.656LysAla: 3.656 ± 0.03	0.655LysCys: 0.655 ± 0.011	3.304LysAsp: 3.304 ± 0.025	3.44LysGlu: 3.44 ± 0.032	1.553LysPhe: 1.553 ± 0.016	2.415LysGly: 2.415 ± 0.02	1.498LysHis: 1.498 ± 0.015	2.691LysIle: 2.691 ± 0.023	4.504LysLys: 4.504 ± 0.039	4.618LysLeu: 4.618 ± 0.031	1.391LysMet: 1.391 ± 0.015	2.751LysAsn: 2.751 ± 0.024	2.367LysPro: 2.367 ± 0.02	2.973LysGln: 2.973 ± 0.025	3.51LysArg: 3.51 ± 0.031	4.132LysSer: 4.132 ± 0.03	3.438LysThr: 3.438 ± 0.029	3.117LysVal: 3.117 ± 0.027	0.653LysTrp: 0.653 ± 0.009	1.812LysTyr: 1.812 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	6.53LeuAla: 6.53 ± 0.034	1.449LeuCys: 1.449 ± 0.017	5.94LeuAsp: 5.94 ± 0.036	5.315LeuGlu: 5.315 ± 0.038	3.735LeuPhe: 3.735 ± 0.036	4.85LeuGly: 4.85 ± 0.031	2.489LeuHis: 2.489 ± 0.023	4.435LeuIle: 4.435 ± 0.034	4.881LeuLys: 4.881 ± 0.029	9.1LeuLeu: 9.1 ± 0.056	2.264LeuMet: 2.264 ± 0.022	3.766LeuAsn: 3.766 ± 0.024	5.119LeuPro: 5.119 ± 0.034	4.506LeuGln: 4.506 ± 0.033	4.418LeuArg: 4.418 ± 0.031	7.674LeuSer: 7.674 ± 0.037	5.433LeuThr: 5.433 ± 0.033	5.697LeuVal: 5.697 ± 0.036	1.097LeuTrp: 1.097 ± 0.013	2.979LeuTyr: 2.979 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.21MetAla: 2.21 ± 0.023	0.277MetCys: 0.277 ± 0.007	2.172MetAsp: 2.172 ± 0.019	1.779MetGlu: 1.779 ± 0.017	0.806MetPhe: 0.806 ± 0.011	1.33MetGly: 1.33 ± 0.016	0.539MetHis: 0.539 ± 0.009	1.502MetIle: 1.502 ± 0.016	1.397MetLys: 1.397 ± 0.016	2.021MetLeu: 2.021 ± 0.018	1.002MetMet: 1.002 ± 0.016	1.369MetAsn: 1.369 ± 0.016	1.087MetPro: 1.087 ± 0.014	0.955MetGln: 0.955 ± 0.012	0.975MetArg: 0.975 ± 0.013	1.819MetSer: 1.819 ± 0.017	2.02MetThr: 2.02 ± 0.02	1.819MetVal: 1.819 ± 0.022	0.232MetTrp: 0.232 ± 0.006	0.751MetTyr: 0.751 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.942AsnAla: 2.942 ± 0.024	0.55AsnCys: 0.55 ± 0.009	3.587AsnAsp: 3.587 ± 0.029	2.558AsnGlu: 2.558 ± 0.02	1.428AsnPhe: 1.428 ± 0.017	3.07AsnGly: 3.07 ± 0.025	1.384AsnHis: 1.384 ± 0.017	2.755AsnIle: 2.755 ± 0.024	2.748AsnLys: 2.748 ± 0.022	3.481AsnLeu: 3.481 ± 0.026	1.248AsnMet: 1.248 ± 0.016	3.772AsnAsn: 3.772 ± 0.041	2.114AsnPro: 2.114 ± 0.02	2.205AsnGln: 2.205 ± 0.021	1.986AsnArg: 1.986 ± 0.018	3.786AsnSer: 3.786 ± 0.029	3.263AsnThr: 3.263 ± 0.024	2.654AsnVal: 2.654 ± 0.02	0.501AsnTrp: 0.501 ± 0.01	1.493AsnTyr: 1.493 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	3.221ProAla: 3.221 ± 0.026	0.564ProCys: 0.564 ± 0.011	2.4ProAsp: 2.4 ± 0.022	2.364ProGlu: 2.364 ± 0.02	1.953ProPhe: 1.953 ± 0.02	2.207ProGly: 2.207 ± 0.022	1.404ProHis: 1.404 ± 0.018	2.6ProIle: 2.6 ± 0.022	2.272ProLys: 2.272 ± 0.025	4.786ProLeu: 4.786 ± 0.032	1.18ProMet: 1.18 ± 0.013	2.061ProAsn: 2.061 ± 0.021	4.575ProPro: 4.575 ± 0.063	2.224ProGln: 2.224 ± 0.025	2.102ProArg: 2.102 ± 0.018	6.286ProSer: 6.286 ± 0.046	4.179ProThr: 4.179 ± 0.032	2.769ProVal: 2.769 ± 0.021	0.545ProTrp: 0.545 ± 0.011	1.534ProTyr: 1.534 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	2.93GlnAla: 2.93 ± 0.028	0.641GlnCys: 0.641 ± 0.011	2.599GlnAsp: 2.599 ± 0.021	2.619GlnGlu: 2.619 ± 0.024	1.547GlnPhe: 1.547 ± 0.018	2.142GlnGly: 2.142 ± 0.021	2.459GlnHis: 2.459 ± 0.027	2.016GlnIle: 2.016 ± 0.018	2.533GlnLys: 2.533 ± 0.02	4.895GlnLeu: 4.895 ± 0.033	1.118GlnMet: 1.118 ± 0.014	1.93GlnAsn: 1.93 ± 0.019	2.687GlnPro: 2.687 ± 0.027	8.628GlnGln: 8.628 ± 0.131	3.013GlnArg: 3.013 ± 0.026	3.618GlnSer: 3.618 ± 0.029	2.502GlnThr: 2.502 ± 0.021	2.701GlnVal: 2.701 ± 0.021	0.642GlnTrp: 0.642 ± 0.012	1.626GlnTyr: 1.626 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	2.674ArgAla: 2.674 ± 0.022	0.677ArgCys: 0.677 ± 0.012	2.356ArgAsp: 2.356 ± 0.022	2.222ArgGlu: 2.222 ± 0.022	1.919ArgPhe: 1.919 ± 0.019	2.261ArgGly: 2.261 ± 0.025	1.786ArgHis: 1.786 ± 0.019	2.667ArgIle: 2.667 ± 0.022	3.172ArgLys: 3.172 ± 0.026	4.938ArgLeu: 4.938 ± 0.028	1.261ArgMet: 1.261 ± 0.014	2.178ArgAsn: 2.178 ± 0.018	2.379ArgPro: 2.379 ± 0.023	3.015ArgGln: 3.015 ± 0.026	3.79ArgArg: 3.79 ± 0.036	3.929ArgSer: 3.929 ± 0.033	2.802ArgThr: 2.802 ± 0.029	2.476ArgVal: 2.476 ± 0.023	0.678ArgTrp: 0.678 ± 0.01	1.732ArgTyr: 1.732 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	5.379SerAla: 5.379 ± 0.038	1.025SerCys: 1.025 ± 0.014	4.35SerAsp: 4.35 ± 0.032	3.205SerGlu: 3.205 ± 0.028	3.331SerPhe: 3.331 ± 0.025	4.421SerGly: 4.421 ± 0.032	2.211SerHis: 2.211 ± 0.021	4.833SerIle: 4.833 ± 0.032	4.101SerLys: 4.101 ± 0.032	7.764SerLeu: 7.764 ± 0.038	2.159SerMet: 2.159 ± 0.019	4.423SerAsn: 4.423 ± 0.034	5.52SerPro: 5.52 ± 0.046	3.369SerGln: 3.369 ± 0.023	3.665SerArg: 3.665 ± 0.027	13.306SerSer: 13.306 ± 0.101	7.325SerThr: 7.325 ± 0.052	4.388SerVal: 4.388 ± 0.031	0.906SerTrp: 0.906 ± 0.014	2.418SerTyr: 2.418 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.781ThrAla: 4.781 ± 0.027	0.909ThrCys: 0.909 ± 0.014	3.391ThrAsp: 3.391 ± 0.027	2.889ThrGlu: 2.889 ± 0.025	2.419ThrPhe: 2.419 ± 0.024	3.495ThrGly: 3.495 ± 0.024	1.636ThrHis: 1.636 ± 0.016	3.856ThrIle: 3.856 ± 0.027	3.504ThrLys: 3.504 ± 0.028	6.052ThrLeu: 6.052 ± 0.036	1.809ThrMet: 1.809 ± 0.017	3.313ThrAsn: 3.313 ± 0.027	4.102ThrPro: 4.102 ± 0.034	2.499ThrGln: 2.499 ± 0.024	2.719ThrArg: 2.719 ± 0.022	6.931ThrSer: 6.931 ± 0.047	7.176ThrThr: 7.176 ± 0.063	3.711ThrVal: 3.711 ± 0.029	0.733ThrTrp: 0.733 ± 0.012	1.849ThrTyr: 1.849 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.153ValAla: 4.153 ± 0.037	0.888ValCys: 0.888 ± 0.013	4.033ValAsp: 4.033 ± 0.031	3.189ValGlu: 3.189 ± 0.031	2.377ValPhe: 2.377 ± 0.021	3.124ValGly: 3.124 ± 0.025	1.391ValHis: 1.391 ± 0.016	3.35ValIle: 3.35 ± 0.023	3.027ValLys: 3.027 ± 0.027	5.292ValLeu: 5.292 ± 0.032	1.56ValMet: 1.56 ± 0.016	2.581ValAsn: 2.581 ± 0.025	2.836ValPro: 2.836 ± 0.026	2.234ValGln: 2.234 ± 0.019	2.485ValArg: 2.485 ± 0.023	4.236ValSer: 4.236 ± 0.03	3.522ValThr: 3.522 ± 0.032	3.992ValVal: 3.992 ± 0.029	0.703ValTrp: 0.703 ± 0.012	1.958ValTyr: 1.958 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.678TrpAla: 0.678 ± 0.01	0.21TrpCys: 0.21 ± 0.006	0.683TrpAsp: 0.683 ± 0.01	0.574TrpGlu: 0.574 ± 0.011	0.523TrpPhe: 0.523 ± 0.01	0.572TrpGly: 0.572 ± 0.011	0.332TrpHis: 0.332 ± 0.007	0.796TrpIle: 0.796 ± 0.013	0.774TrpLys: 0.774 ± 0.012	1.122TrpLeu: 1.122 ± 0.015	0.416TrpMet: 0.416 ± 0.008	0.638TrpAsn: 0.638 ± 0.011	0.396TrpPro: 0.396 ± 0.007	0.57TrpGln: 0.57 ± 0.011	0.651TrpArg: 0.651 ± 0.009	0.928TrpSer: 0.928 ± 0.013	0.814TrpThr: 0.814 ± 0.017	0.663TrpVal: 0.663 ± 0.011	0.213TrpTrp: 0.213 ± 0.007	0.41TrpTyr: 0.41 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.942TyrAla: 1.942 ± 0.017	0.621TyrCys: 0.621 ± 0.01	2.11TyrAsp: 2.11 ± 0.019	1.662TyrGlu: 1.662 ± 0.018	1.423TyrPhe: 1.423 ± 0.016	2.021TyrGly: 2.021 ± 0.019	1.174TyrHis: 1.174 ± 0.013	1.859TyrIle: 1.859 ± 0.018	1.508TyrLys: 1.508 ± 0.019	3.159TyrLeu: 3.159 ± 0.025	0.843TyrMet: 0.843 ± 0.011	1.533TyrAsn: 1.533 ± 0.016	1.508TyrPro: 1.508 ± 0.017	1.819TyrGln: 1.819 ± 0.02	1.727TyrArg: 1.727 ± 0.018	2.469TyrSer: 2.469 ± 0.019	1.861TyrThr: 1.861 ± 0.019	1.816TyrVal: 1.816 ± 0.02	0.442TyrTrp: 0.442 ± 0.009	1.419TyrTyr: 1.419 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 14767 proteins (6231592 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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