Amino acid dipepetide frequency for Lyngbya confervoides BDU141951

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.057AlaAla: 12.057 ± 0.106	0.979AlaCys: 0.979 ± 0.031	6.101AlaAsp: 6.101 ± 0.066	6.64AlaGlu: 6.64 ± 0.078	3.707AlaPhe: 3.707 ± 0.044	7.68AlaGly: 7.68 ± 0.105	1.911AlaHis: 1.911 ± 0.038	7.347AlaIle: 7.347 ± 0.066	3.099AlaLys: 3.099 ± 0.05	10.97AlaLeu: 10.97 ± 0.099	2.588AlaMet: 2.588 ± 0.049	3.098AlaAsn: 3.098 ± 0.055	4.514AlaPro: 4.514 ± 0.067	5.076AlaGln: 5.076 ± 0.058	5.142AlaArg: 5.142 ± 0.075	5.175AlaSer: 5.175 ± 0.06	5.958AlaThr: 5.958 ± 0.067	7.078AlaVal: 7.078 ± 0.068	1.355AlaTrp: 1.355 ± 0.03	2.631AlaTyr: 2.631 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.775CysAla: 0.775 ± 0.023	0.14CysCys: 0.14 ± 0.01	0.675CysAsp: 0.675 ± 0.024	0.542CysGlu: 0.542 ± 0.019	0.393CysPhe: 0.393 ± 0.015	0.857CysGly: 0.857 ± 0.026	0.282CysHis: 0.282 ± 0.013	0.453CysIle: 0.453 ± 0.016	0.227CysLys: 0.227 ± 0.012	0.985CysLeu: 0.985 ± 0.027	0.154CysMet: 0.154 ± 0.01	0.294CysAsn: 0.294 ± 0.014	0.551CysPro: 0.551 ± 0.019	0.472CysGln: 0.472 ± 0.018	0.601CysArg: 0.601 ± 0.021	0.512CysSer: 0.512 ± 0.019	0.506CysThr: 0.506 ± 0.019	0.626CysVal: 0.626 ± 0.023	0.128CysTrp: 0.128 ± 0.009	0.283CysTyr: 0.283 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	5.593AspAla: 5.593 ± 0.074	0.613AspCys: 0.613 ± 0.022	3.245AspAsp: 3.245 ± 0.072	3.766AspGlu: 3.766 ± 0.055	2.565AspPhe: 2.565 ± 0.041	4.389AspGly: 4.389 ± 0.095	1.149AspHis: 1.149 ± 0.029	3.256AspIle: 3.256 ± 0.052	1.524AspLys: 1.524 ± 0.035	6.395AspLeu: 6.395 ± 0.078	1.167AspMet: 1.167 ± 0.026	1.701AspAsn: 1.701 ± 0.038	3.162AspPro: 3.162 ± 0.051	2.317AspGln: 2.317 ± 0.034	4.408AspArg: 4.408 ± 0.054	2.692AspSer: 2.692 ± 0.046	2.95AspThr: 2.95 ± 0.048	3.73AspVal: 3.73 ± 0.056	1.127AspTrp: 1.127 ± 0.025	1.933AspTyr: 1.933 ± 0.036	0.002AspXaa: 0.002 ± 0.001
Glu	7.047GluAla: 7.047 ± 0.074	0.378GluCys: 0.378 ± 0.015	3.029GluAsp: 3.029 ± 0.051	3.574GluGlu: 3.574 ± 0.058	2.09GluPhe: 2.09 ± 0.037	4.033GluGly: 4.033 ± 0.055	1.201GluHis: 1.201 ± 0.023	3.616GluIle: 3.616 ± 0.051	2.225GluLys: 2.225 ± 0.036	6.358GluLeu: 6.358 ± 0.075	1.515GluMet: 1.515 ± 0.034	1.904GluAsn: 1.904 ± 0.035	2.881GluPro: 2.881 ± 0.043	3.159GluGln: 3.159 ± 0.052	3.744GluArg: 3.744 ± 0.052	3.02GluSer: 3.02 ± 0.056	3.776GluThr: 3.776 ± 0.045	4.351GluVal: 4.351 ± 0.052	0.801GluTrp: 0.801 ± 0.024	1.434GluTyr: 1.434 ± 0.032	0.001GluXaa: 0.001 ± 0.001
Phe	3.741PheAla: 3.741 ± 0.048	0.48PheCys: 0.48 ± 0.02	2.574PheAsp: 2.574 ± 0.038	2.399PheGlu: 2.399 ± 0.042	1.669PhePhe: 1.669 ± 0.036	3.29PheGly: 3.29 ± 0.048	0.719PheHis: 0.719 ± 0.019	1.998PheIle: 1.998 ± 0.038	1.132PheLys: 1.132 ± 0.028	3.699PheLeu: 3.699 ± 0.05	0.787PheMet: 0.787 ± 0.022	1.366PheAsn: 1.366 ± 0.029	1.746PhePro: 1.746 ± 0.035	1.63PheGln: 1.63 ± 0.032	2.044PheArg: 2.044 ± 0.038	2.479PheSer: 2.479 ± 0.048	2.368PheThr: 2.368 ± 0.047	2.718PheVal: 2.718 ± 0.043	0.711PheTrp: 0.711 ± 0.02	1.135PheTyr: 1.135 ± 0.026	0.001PheXaa: 0.001 ± 0.001
Gly	6.701GlyAla: 6.701 ± 0.086	0.885GlyCys: 0.885 ± 0.028	4.478GlyAsp: 4.478 ± 0.106	4.302GlyGlu: 4.302 ± 0.056	3.216GlyPhe: 3.216 ± 0.047	5.78GlyGly: 5.78 ± 0.108	1.621GlyHis: 1.621 ± 0.036	4.669GlyIle: 4.669 ± 0.064	2.719GlyLys: 2.719 ± 0.05	8.125GlyLeu: 8.125 ± 0.071	1.866GlyMet: 1.866 ± 0.034	2.664GlyAsn: 2.664 ± 0.067	2.475GlyPro: 2.475 ± 0.045	3.567GlyGln: 3.567 ± 0.052	4.169GlyArg: 4.169 ± 0.051	4.153GlySer: 4.153 ± 0.081	4.499GlyThr: 4.499 ± 0.082	5.372GlyVal: 5.372 ± 0.064	1.266GlyTrp: 1.266 ± 0.027	2.376GlyTyr: 2.376 ± 0.041	0.001GlyXaa: 0.001 ± 0.001
His	1.589HisAla: 1.589 ± 0.034	0.284HisCys: 0.284 ± 0.013	1.073HisAsp: 1.073 ± 0.025	1.032HisGlu: 1.032 ± 0.024	0.878HisPhe: 0.878 ± 0.023	1.466HisGly: 1.466 ± 0.028	0.69HisHis: 0.69 ± 0.026	1.058HisIle: 1.058 ± 0.027	0.525HisLys: 0.525 ± 0.02	2.332HisLeu: 2.332 ± 0.043	0.384HisMet: 0.384 ± 0.016	0.609HisAsn: 0.609 ± 0.021	1.479HisPro: 1.479 ± 0.034	1.131HisGln: 1.131 ± 0.03	1.331HisArg: 1.331 ± 0.031	1.023HisSer: 1.023 ± 0.022	1.086HisThr: 1.086 ± 0.025	1.148HisVal: 1.148 ± 0.03	0.404HisTrp: 0.404 ± 0.016	0.691HisTyr: 0.691 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.547IleAla: 7.547 ± 0.072	0.578IleCys: 0.578 ± 0.017	3.694IleAsp: 3.694 ± 0.05	3.623IleGlu: 3.623 ± 0.048	1.97IlePhe: 1.97 ± 0.037	4.432IleGly: 4.432 ± 0.058	1.084IleHis: 1.084 ± 0.027	2.532IleIle: 2.532 ± 0.044	1.562IleLys: 1.562 ± 0.033	5.081IleLeu: 5.081 ± 0.061	0.919IleMet: 0.919 ± 0.025	1.916IleAsn: 1.916 ± 0.037	2.771IlePro: 2.771 ± 0.047	2.277IleGln: 2.277 ± 0.035	2.992IleArg: 2.992 ± 0.046	3.107IleSer: 3.107 ± 0.05	3.253IleThr: 3.253 ± 0.06	4.073IleVal: 4.073 ± 0.056	0.756IleTrp: 0.756 ± 0.021	1.468IleTyr: 1.468 ± 0.034	0.001IleXaa: 0.001 ± 0.001
Lys	3.474LysAla: 3.474 ± 0.048	0.19LysCys: 0.19 ± 0.011	1.585LysAsp: 1.585 ± 0.035	1.688LysGlu: 1.688 ± 0.038	1.021LysPhe: 1.021 ± 0.028	2.085LysGly: 2.085 ± 0.04	0.61LysHis: 0.61 ± 0.018	1.764LysIle: 1.764 ± 0.036	1.267LysLys: 1.267 ± 0.034	3.314LysLeu: 3.314 ± 0.049	0.699LysMet: 0.699 ± 0.024	0.94LysAsn: 0.94 ± 0.022	1.729LysPro: 1.729 ± 0.035	1.551LysGln: 1.551 ± 0.031	2.041LysArg: 2.041 ± 0.043	1.815LysSer: 1.815 ± 0.035	2.027LysThr: 2.027 ± 0.039	2.36LysVal: 2.36 ± 0.044	0.364LysTrp: 0.364 ± 0.015	0.814LysTyr: 0.814 ± 0.023	0.001LysXaa: 0.001 ± 0.001
Leu	11.106LeuAla: 11.106 ± 0.09	0.953LeuCys: 0.953 ± 0.027	5.978LeuAsp: 5.978 ± 0.072	6.466LeuGlu: 6.466 ± 0.072	3.756LeuPhe: 3.756 ± 0.055	7.937LeuGly: 7.937 ± 0.084	1.923LeuHis: 1.923 ± 0.036	5.521LeuIle: 5.521 ± 0.06	4.017LeuLys: 4.017 ± 0.057	10.775LeuLeu: 10.775 ± 0.103	2.552LeuMet: 2.552 ± 0.044	3.604LeuAsn: 3.604 ± 0.05	6.014LeuPro: 6.014 ± 0.077	5.245LeuGln: 5.245 ± 0.075	6.018LeuArg: 6.018 ± 0.063	7.095LeuSer: 7.095 ± 0.069	6.733LeuThr: 6.733 ± 0.08	7.388LeuVal: 7.388 ± 0.076	1.458LeuTrp: 1.458 ± 0.037	2.635LeuTyr: 2.635 ± 0.042	0.001LeuXaa: 0.001 ± 0.001
Met	2.638MetAla: 2.638 ± 0.041	0.139MetCys: 0.139 ± 0.01	1.002MetAsp: 1.002 ± 0.024	1.101MetGlu: 1.101 ± 0.027	0.64MetPhe: 0.64 ± 0.02	1.751MetGly: 1.751 ± 0.034	0.397MetHis: 0.397 ± 0.016	1.122MetIle: 1.122 ± 0.029	0.832MetLys: 0.832 ± 0.023	2.174MetLeu: 2.174 ± 0.038	0.574MetMet: 0.574 ± 0.021	0.743MetAsn: 0.743 ± 0.023	1.336MetPro: 1.336 ± 0.033	1.024MetGln: 1.024 ± 0.03	1.338MetArg: 1.338 ± 0.032	1.363MetSer: 1.363 ± 0.03	1.681MetThr: 1.681 ± 0.035	1.677MetVal: 1.677 ± 0.034	0.179MetTrp: 0.179 ± 0.011	0.402MetTyr: 0.402 ± 0.016	0.001MetXaa: 0.001 ± 0.001
Asn	2.999AsnAla: 2.999 ± 0.051	0.348AsnCys: 0.348 ± 0.017	1.66AsnAsp: 1.66 ± 0.046	1.48AsnGlu: 1.48 ± 0.03	1.323AsnPhe: 1.323 ± 0.031	2.575AsnGly: 2.575 ± 0.061	0.692AsnHis: 0.692 ± 0.022	1.751AsnIle: 1.751 ± 0.042	0.782AsnLys: 0.782 ± 0.023	3.804AsnLeu: 3.804 ± 0.062	0.545AsnMet: 0.545 ± 0.017	1.065AsnAsn: 1.065 ± 0.03	2.262AsnPro: 2.262 ± 0.035	1.616AsnGln: 1.616 ± 0.034	2.064AsnArg: 2.064 ± 0.036	1.669AsnSer: 1.669 ± 0.035	1.787AsnThr: 1.787 ± 0.043	2.036AsnVal: 2.036 ± 0.042	0.572AsnTrp: 0.572 ± 0.019	0.962AsnTyr: 0.962 ± 0.025	0.001AsnXaa: 0.001 ± 0.001
Pro	5.037ProAla: 5.037 ± 0.08	0.388ProCys: 0.388 ± 0.015	3.945ProAsp: 3.945 ± 0.049	4.111ProGlu: 4.111 ± 0.053	1.956ProPhe: 1.956 ± 0.037	3.854ProGly: 3.854 ± 0.052	1.07ProHis: 1.07 ± 0.026	2.63ProIle: 2.63 ± 0.039	1.554ProLys: 1.554 ± 0.031	5.067ProLeu: 5.067 ± 0.066	1.067ProMet: 1.067 ± 0.024	1.725ProAsn: 1.725 ± 0.035	2.809ProPro: 2.809 ± 0.057	2.393ProGln: 2.393 ± 0.039	2.157ProArg: 2.157 ± 0.037	2.865ProSer: 2.865 ± 0.05	3.146ProThr: 3.146 ± 0.045	3.834ProVal: 3.834 ± 0.058	0.75ProTrp: 0.75 ± 0.026	1.434ProTyr: 1.434 ± 0.033	0.002ProXaa: 0.002 ± 0.001
Gln	5.604GlnAla: 5.604 ± 0.085	0.339GlnCys: 0.339 ± 0.014	2.075GlnAsp: 2.075 ± 0.033	2.498GlnGlu: 2.498 ± 0.044	1.774GlnPhe: 1.774 ± 0.037	3.276GlnGly: 3.276 ± 0.048	0.993GlnHis: 0.993 ± 0.031	2.702GlnIle: 2.702 ± 0.039	1.571GlnLys: 1.571 ± 0.032	5.436GlnLeu: 5.436 ± 0.082	1.044GlnMet: 1.044 ± 0.027	1.36GlnAsn: 1.36 ± 0.033	2.676GlnPro: 2.676 ± 0.045	3.373GlnGln: 3.373 ± 0.073	3.252GlnArg: 3.252 ± 0.055	2.7GlnSer: 2.7 ± 0.04	2.88GlnThr: 2.88 ± 0.04	3.673GlnVal: 3.673 ± 0.049	0.752GlnTrp: 0.752 ± 0.022	1.148GlnTyr: 1.148 ± 0.028	0.001GlnXaa: 0.001 ± 0.001
Arg	4.922ArgAla: 4.922 ± 0.065	0.539ArgCys: 0.539 ± 0.019	3.413ArgAsp: 3.413 ± 0.041	3.366ArgGlu: 3.366 ± 0.048	2.523ArgPhe: 2.523 ± 0.036	3.437ArgGly: 3.437 ± 0.053	1.376ArgHis: 1.376 ± 0.029	3.27ArgIle: 3.27 ± 0.038	1.883ArgLys: 1.883 ± 0.037	6.762ArgLeu: 6.762 ± 0.074	1.363ArgMet: 1.363 ± 0.031	1.779ArgAsn: 1.779 ± 0.033	2.806ArgPro: 2.806 ± 0.047	3.482ArgGln: 3.482 ± 0.053	3.995ArgArg: 3.995 ± 0.061	3.531ArgSer: 3.531 ± 0.051	2.785ArgThr: 2.785 ± 0.037	3.831ArgVal: 3.831 ± 0.052	1.032ArgTrp: 1.032 ± 0.027	1.965ArgTyr: 1.965 ± 0.038	0.001ArgXaa: 0.001 ± 0.001
Ser	5.205SerAla: 5.205 ± 0.054	0.491SerCys: 0.491 ± 0.018	3.329SerAsp: 3.329 ± 0.048	3.195SerGlu: 3.195 ± 0.042	2.257SerPhe: 2.257 ± 0.037	4.778SerGly: 4.778 ± 0.068	1.16SerHis: 1.16 ± 0.028	2.89SerIle: 2.89 ± 0.053	1.601SerLys: 1.601 ± 0.033	6.319SerLeu: 6.319 ± 0.069	1.245SerMet: 1.245 ± 0.025	1.772SerAsn: 1.772 ± 0.034	3.252SerPro: 3.252 ± 0.041	2.656SerGln: 2.656 ± 0.04	3.12SerArg: 3.12 ± 0.042	3.385SerSer: 3.385 ± 0.058	3.244SerThr: 3.244 ± 0.049	3.835SerVal: 3.835 ± 0.051	0.84SerTrp: 0.84 ± 0.022	1.532SerTyr: 1.532 ± 0.03	0.001SerXaa: 0.001 ± 0.001
Thr	6.364ThrAla: 6.364 ± 0.071	0.54ThrCys: 0.54 ± 0.022	3.333ThrAsp: 3.333 ± 0.058	3.198ThrGlu: 3.198 ± 0.043	2.397ThrPhe: 2.397 ± 0.048	4.768ThrGly: 4.768 ± 0.079	1.161ThrHis: 1.161 ± 0.028	3.087ThrIle: 3.087 ± 0.049	1.387ThrLys: 1.387 ± 0.029	7.137ThrLeu: 7.137 ± 0.073	1.024ThrMet: 1.024 ± 0.029	1.666ThrAsn: 1.666 ± 0.042	3.586ThrPro: 3.586 ± 0.049	2.491ThrGln: 2.491 ± 0.053	2.766ThrArg: 2.766 ± 0.041	2.945ThrSer: 2.945 ± 0.051	3.46ThrThr: 3.46 ± 0.055	4.984ThrVal: 4.984 ± 0.073	0.805ThrTrp: 0.805 ± 0.021	1.756ThrTyr: 1.756 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	7.145ValAla: 7.145 ± 0.071	0.675ValCys: 0.675 ± 0.019	4.12ValAsp: 4.12 ± 0.059	4.647ValGlu: 4.647 ± 0.055	2.702ValPhe: 2.702 ± 0.048	5.196ValGly: 5.196 ± 0.06	1.218ValHis: 1.218 ± 0.027	4.001ValIle: 4.001 ± 0.054	2.25ValLys: 2.25 ± 0.039	7.326ValLeu: 7.326 ± 0.071	1.796ValMet: 1.796 ± 0.03	2.493ValAsn: 2.493 ± 0.055	3.658ValPro: 3.658 ± 0.052	2.934ValGln: 2.934 ± 0.042	3.846ValArg: 3.846 ± 0.046	4.218ValSer: 4.218 ± 0.058	4.546ValThr: 4.546 ± 0.07	5.343ValVal: 5.343 ± 0.059	0.947ValTrp: 0.947 ± 0.026	1.798ValTyr: 1.798 ± 0.031	0.001ValXaa: 0.001 ± 0.001
Trp	1.183TrpAla: 1.183 ± 0.028	0.166TrpCys: 0.166 ± 0.009	0.664TrpAsp: 0.664 ± 0.021	0.827TrpGlu: 0.827 ± 0.024	0.664TrpPhe: 0.664 ± 0.021	1.06TrpGly: 1.06 ± 0.024	0.355TrpHis: 0.355 ± 0.015	0.751TrpIle: 0.751 ± 0.025	0.422TrpLys: 0.422 ± 0.015	2.012TrpLeu: 2.012 ± 0.038	0.378TrpMet: 0.378 ± 0.014	0.452TrpAsn: 0.452 ± 0.017	0.657TrpPro: 0.657 ± 0.021	1.205TrpGln: 1.205 ± 0.03	0.972TrpArg: 0.972 ± 0.021	0.854TrpSer: 0.854 ± 0.023	0.684TrpThr: 0.684 ± 0.017	1.058TrpVal: 1.058 ± 0.029	0.268TrpTrp: 0.268 ± 0.013	0.389TrpTyr: 0.389 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.381TyrAla: 2.381 ± 0.041	0.351TyrCys: 0.351 ± 0.016	1.71TyrAsp: 1.71 ± 0.041	1.679TyrGlu: 1.679 ± 0.034	1.185TyrPhe: 1.185 ± 0.026	2.258TyrGly: 2.258 ± 0.039	0.603TyrHis: 0.603 ± 0.019	1.215TyrIle: 1.215 ± 0.025	0.759TyrLys: 0.759 ± 0.023	3.101TyrLeu: 3.101 ± 0.045	0.446TyrMet: 0.446 ± 0.018	0.841TyrAsn: 0.841 ± 0.025	1.429TyrPro: 1.429 ± 0.03	1.527TyrGln: 1.527 ± 0.032	2.061TyrArg: 2.061 ± 0.034	1.505TyrSer: 1.505 ± 0.034	1.487TyrThr: 1.487 ± 0.034	1.744TyrVal: 1.744 ± 0.032	0.505TyrTrp: 0.505 ± 0.017	0.936TyrTyr: 0.936 ± 0.023	0.001TyrXaa: 0.001 ± 0.001
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.001XaaGlu: 0.001 ± 0.001	0.002XaaPhe: 0.002 ± 0.001	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.001	0.001XaaLys: 0.001 ± 0.001	0.003XaaLeu: 0.003 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.001XaaSer: 0.001 ± 0.001	0.001XaaThr: 0.001 ± 0.001	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.005XaaXaa: 0.005 ± 0.005

Statistics based on 6060 proteins (1735983 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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