Amino acid dipepetide frequency for Idotea virus IWaV278

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.804AlaAla: 7.804 ± 0.168
0.0AlaCys: 0.0 ± 0.0
4.459AlaAsp: 4.459 ± 1.739
4.459AlaGlu: 4.459 ± 1.739
2.23AlaPhe: 2.23 ± 1.271
4.459AlaGly: 4.459 ± 2.542
1.115AlaHis: 1.115 ± 0.791
4.459AlaIle: 4.459 ± 0.312
3.344AlaLys: 3.344 ± 0.947
6.689AlaLeu: 6.689 ± 0.959
4.459AlaMet: 4.459 ± 1.497
5.574AlaAsn: 5.574 ± 1.751
5.574AlaPro: 5.574 ± 1.103
7.804AlaGln: 7.804 ± 1.259
5.574AlaArg: 5.574 ± 2.53
2.23AlaSer: 2.23 ± 1.271
5.574AlaThr: 5.574 ± 1.103
3.344AlaVal: 3.344 ± 2.374
0.0AlaTrp: 0.0 ± 0.0
1.115AlaTyr: 1.115 ± 0.791
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.115CysPhe: 1.115 ± 0.791
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.23CysLys: 2.23 ± 0.156
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.23CysAsn: 2.23 ± 1.583
1.115CysPro: 1.115 ± 0.791
0.0CysGln: 0.0 ± 0.0
1.115CysArg: 1.115 ± 0.791
1.115CysSer: 1.115 ± 0.636
2.23CysThr: 2.23 ± 0.156
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.804AspAla: 7.804 ± 1.259
0.0AspCys: 0.0 ± 0.0
5.574AspAsp: 5.574 ± 1.751
4.459AspGlu: 4.459 ± 1.739
3.344AspPhe: 3.344 ± 2.374
4.459AspGly: 4.459 ± 0.312
0.0AspHis: 0.0 ± 0.0
4.459AspIle: 4.459 ± 1.739
2.23AspLys: 2.23 ± 0.156
5.574AspLeu: 5.574 ± 1.103
1.115AspMet: 1.115 ± 0.636
0.0AspAsn: 0.0 ± 0.0
3.344AspPro: 3.344 ± 0.48
1.115AspGln: 1.115 ± 0.636
0.0AspArg: 0.0 ± 0.0
3.344AspSer: 3.344 ± 1.907
4.459AspThr: 4.459 ± 1.739
2.23AspVal: 2.23 ± 0.156
0.0AspTrp: 0.0 ± 0.0
4.459AspTyr: 4.459 ± 1.115
0.0AspXaa: 0.0 ± 0.0
Glu
3.344GluAla: 3.344 ± 0.947
1.115GluCys: 1.115 ± 0.791
5.574GluAsp: 5.574 ± 2.53
1.115GluGlu: 1.115 ± 0.791
6.689GluPhe: 6.689 ± 2.386
6.689GluGly: 6.689 ± 1.895
1.115GluHis: 1.115 ± 0.636
3.344GluIle: 3.344 ± 2.374
0.0GluLys: 0.0 ± 0.0
4.459GluLeu: 4.459 ± 1.115
2.23GluMet: 2.23 ± 1.583
2.23GluAsn: 2.23 ± 1.271
2.23GluPro: 2.23 ± 1.583
1.115GluGln: 1.115 ± 0.636
1.115GluArg: 1.115 ± 0.791
0.0GluSer: 0.0 ± 0.0
3.344GluThr: 3.344 ± 0.48
1.115GluVal: 1.115 ± 0.791
2.23GluTrp: 2.23 ± 0.156
4.459GluTyr: 4.459 ± 1.115
0.0GluXaa: 0.0 ± 0.0
Phe
2.23PheAla: 2.23 ± 0.156
1.115PheCys: 1.115 ± 0.791
3.344PheAsp: 3.344 ± 0.48
5.574PheGlu: 5.574 ± 1.751
0.0PhePhe: 0.0 ± 0.0
6.689PheGly: 6.689 ± 0.959
0.0PheHis: 0.0 ± 0.0
1.115PheIle: 1.115 ± 0.791
3.344PheLys: 3.344 ± 0.48
3.344PheLeu: 3.344 ± 0.48
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.115PhePro: 1.115 ± 0.636
3.344PheGln: 3.344 ± 1.907
0.0PheArg: 0.0 ± 0.0
2.23PheSer: 2.23 ± 1.271
7.804PheThr: 7.804 ± 0.168
3.344PheVal: 3.344 ± 0.48
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
10.033GlyAla: 10.033 ± 1.439
1.115GlyCys: 1.115 ± 0.791
5.574GlyAsp: 5.574 ± 1.751
5.574GlyGlu: 5.574 ± 3.178
1.115GlyPhe: 1.115 ± 0.636
8.919GlyGly: 8.919 ± 3.657
1.115GlyHis: 1.115 ± 0.791
3.344GlyIle: 3.344 ± 0.48
7.804GlyLys: 7.804 ± 1.259
4.459GlyLeu: 4.459 ± 1.115
0.0GlyMet: 0.0 ± 0.0
1.115GlyAsn: 1.115 ± 0.636
2.23GlyPro: 2.23 ± 1.271
3.344GlyGln: 3.344 ± 0.947
2.23GlyArg: 2.23 ± 0.156
7.804GlySer: 7.804 ± 0.168
7.804GlyThr: 7.804 ± 1.595
6.689GlyVal: 6.689 ± 3.813
1.115GlyTrp: 1.115 ± 0.636
5.574GlyTyr: 5.574 ± 1.103
0.0GlyXaa: 0.0 ± 0.0
His
1.115HisAla: 1.115 ± 0.791
1.115HisCys: 1.115 ± 0.791
0.0HisAsp: 0.0 ± 0.0
1.115HisGlu: 1.115 ± 0.791
1.115HisPhe: 1.115 ± 0.791
1.115HisGly: 1.115 ± 0.636
1.115HisHis: 1.115 ± 0.791
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.344HisLeu: 3.344 ± 0.947
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.115HisPro: 1.115 ± 0.636
1.115HisGln: 1.115 ± 0.791
1.115HisArg: 1.115 ± 0.636
0.0HisSer: 0.0 ± 0.0
2.23HisThr: 2.23 ± 0.156
2.23HisVal: 2.23 ± 1.583
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.689IleAla: 6.689 ± 0.468
1.115IleCys: 1.115 ± 0.636
1.115IleAsp: 1.115 ± 0.791
1.115IleGlu: 1.115 ± 0.791
0.0IlePhe: 0.0 ± 0.0
3.344IleGly: 3.344 ± 0.48
3.344IleHis: 3.344 ± 0.947
1.115IleIle: 1.115 ± 0.791
2.23IleLys: 2.23 ± 1.583
3.344IleLeu: 3.344 ± 2.374
0.0IleMet: 0.0 ± 0.0
1.115IleAsn: 1.115 ± 0.791
1.115IlePro: 1.115 ± 0.791
2.23IleGln: 2.23 ± 1.583
1.115IleArg: 1.115 ± 0.791
1.115IleSer: 1.115 ± 0.636
4.459IleThr: 4.459 ± 1.115
4.459IleVal: 4.459 ± 1.739
1.115IleTrp: 1.115 ± 0.791
1.115IleTyr: 1.115 ± 0.791
0.0IleXaa: 0.0 ± 0.0
Lys
4.459LysAla: 4.459 ± 1.115
0.0LysCys: 0.0 ± 0.0
1.115LysAsp: 1.115 ± 0.791
0.0LysGlu: 0.0 ± 0.0
3.344LysPhe: 3.344 ± 1.907
5.574LysGly: 5.574 ± 0.324
0.0LysHis: 0.0 ± 0.0
2.23LysIle: 2.23 ± 1.583
1.115LysLys: 1.115 ± 0.636
3.344LysLeu: 3.344 ± 1.907
0.0LysMet: 0.0 ± 0.0
2.23LysAsn: 2.23 ± 0.156
2.23LysPro: 2.23 ± 1.271
4.459LysGln: 4.459 ± 1.739
6.689LysArg: 6.689 ± 1.895
4.459LysSer: 4.459 ± 0.312
2.23LysThr: 2.23 ± 1.271
4.459LysVal: 4.459 ± 1.115
1.115LysTrp: 1.115 ± 0.791
3.344LysTyr: 3.344 ± 0.947
0.0LysXaa: 0.0 ± 0.0
Leu
4.459LeuAla: 4.459 ± 0.312
1.115LeuCys: 1.115 ± 0.791
3.344LeuAsp: 3.344 ± 2.374
3.344LeuGlu: 3.344 ± 0.48
2.23LeuPhe: 2.23 ± 1.271
7.804LeuGly: 7.804 ± 1.595
2.23LeuHis: 2.23 ± 0.156
3.344LeuIle: 3.344 ± 0.48
2.23LeuLys: 2.23 ± 1.583
4.459LeuLeu: 4.459 ± 3.166
3.344LeuMet: 3.344 ± 1.907
2.23LeuAsn: 2.23 ± 1.271
4.459LeuPro: 4.459 ± 0.312
3.344LeuGln: 3.344 ± 2.374
4.459LeuArg: 4.459 ± 0.312
3.344LeuSer: 3.344 ± 1.907
2.23LeuThr: 2.23 ± 0.156
3.344LeuVal: 3.344 ± 0.947
1.115LeuTrp: 1.115 ± 0.636
4.459LeuTyr: 4.459 ± 0.312
0.0LeuXaa: 0.0 ± 0.0
Met
3.344MetAla: 3.344 ± 0.48
1.115MetCys: 1.115 ± 0.636
0.0MetAsp: 0.0 ± 0.0
2.23MetGlu: 2.23 ± 0.156
1.115MetPhe: 1.115 ± 0.636
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.23MetLys: 2.23 ± 1.271
0.0MetLeu: 0.0 ± 0.0
1.115MetMet: 1.115 ± 0.582
0.0MetAsn: 0.0 ± 0.0
1.115MetPro: 1.115 ± 0.791
1.115MetGln: 1.115 ± 0.791
1.115MetArg: 1.115 ± 0.636
4.459MetSer: 4.459 ± 2.542
1.115MetThr: 1.115 ± 0.636
0.0MetVal: 0.0 ± 0.0
1.115MetTrp: 1.115 ± 0.636
1.115MetTyr: 1.115 ± 0.636
0.0MetXaa: 0.0 ± 0.0
Asn
3.344AsnAla: 3.344 ± 0.947
1.115AsnCys: 1.115 ± 0.636
0.0AsnAsp: 0.0 ± 0.0
3.344AsnGlu: 3.344 ± 2.374
2.23AsnPhe: 2.23 ± 1.271
4.459AsnGly: 4.459 ± 1.739
0.0AsnHis: 0.0 ± 0.0
2.23AsnIle: 2.23 ± 0.156
1.115AsnLys: 1.115 ± 0.636
0.0AsnLeu: 0.0 ± 0.0
1.115AsnMet: 1.115 ± 0.636
2.23AsnAsn: 2.23 ± 0.156
1.115AsnPro: 1.115 ± 0.636
2.23AsnGln: 2.23 ± 0.156
3.344AsnArg: 3.344 ± 0.48
4.459AsnSer: 4.459 ± 2.542
3.344AsnThr: 3.344 ± 0.48
3.344AsnVal: 3.344 ± 1.907
1.115AsnTrp: 1.115 ± 0.636
4.459AsnTyr: 4.459 ± 0.312
0.0AsnXaa: 0.0 ± 0.0
Pro
4.459ProAla: 4.459 ± 1.739
0.0ProCys: 0.0 ± 0.0
4.459ProAsp: 4.459 ± 0.312
7.804ProGlu: 7.804 ± 0.168
2.23ProPhe: 2.23 ± 1.271
1.115ProGly: 1.115 ± 0.636
0.0ProHis: 0.0 ± 0.0
1.115ProIle: 1.115 ± 0.791
0.0ProLys: 0.0 ± 0.0
5.574ProLeu: 5.574 ± 2.53
1.115ProMet: 1.115 ± 0.791
4.459ProAsn: 4.459 ± 1.739
4.459ProPro: 4.459 ± 0.312
2.23ProGln: 2.23 ± 1.583
1.115ProArg: 1.115 ± 0.636
3.344ProSer: 3.344 ± 1.907
1.115ProThr: 1.115 ± 0.636
6.689ProVal: 6.689 ± 3.322
1.115ProTrp: 1.115 ± 0.791
1.115ProTyr: 1.115 ± 0.636
0.0ProXaa: 0.0 ± 0.0
Gln
6.689GlnAla: 6.689 ± 3.322
0.0GlnCys: 0.0 ± 0.0
1.115GlnAsp: 1.115 ± 0.791
3.344GlnGlu: 3.344 ± 2.374
4.459GlnPhe: 4.459 ± 0.312
5.574GlnGly: 5.574 ± 1.103
0.0GlnHis: 0.0 ± 0.0
4.459GlnIle: 4.459 ± 1.739
1.115GlnLys: 1.115 ± 0.636
4.459GlnLeu: 4.459 ± 0.312
2.23GlnMet: 2.23 ± 1.271
6.689GlnAsn: 6.689 ± 0.959
2.23GlnPro: 2.23 ± 1.583
4.459GlnGln: 4.459 ± 1.739
5.574GlnArg: 5.574 ± 0.324
2.23GlnSer: 2.23 ± 1.271
1.115GlnThr: 1.115 ± 0.636
3.344GlnVal: 3.344 ± 1.907
1.115GlnTrp: 1.115 ± 0.791
1.115GlnTyr: 1.115 ± 0.636
0.0GlnXaa: 0.0 ± 0.0
Arg
1.115ArgAla: 1.115 ± 0.636
0.0ArgCys: 0.0 ± 0.0
3.344ArgAsp: 3.344 ± 0.48
1.115ArgGlu: 1.115 ± 0.636
3.344ArgPhe: 3.344 ± 0.48
4.459ArgGly: 4.459 ± 1.115
2.23ArgHis: 2.23 ± 1.583
2.23ArgIle: 2.23 ± 1.583
5.574ArgLys: 5.574 ± 2.53
4.459ArgLeu: 4.459 ± 1.739
0.0ArgMet: 0.0 ± 0.0
2.23ArgAsn: 2.23 ± 0.156
4.459ArgPro: 4.459 ± 3.166
4.459ArgGln: 4.459 ± 0.312
3.344ArgArg: 3.344 ± 0.947
4.459ArgSer: 4.459 ± 1.115
2.23ArgThr: 2.23 ± 1.271
1.115ArgVal: 1.115 ± 0.791
1.115ArgTrp: 1.115 ± 0.791
2.23ArgTyr: 2.23 ± 1.271
0.0ArgXaa: 0.0 ± 0.0
Ser
4.459SerAla: 4.459 ± 2.542
0.0SerCys: 0.0 ± 0.0
2.23SerAsp: 2.23 ± 1.271
0.0SerGlu: 0.0 ± 0.0
2.23SerPhe: 2.23 ± 1.271
6.689SerGly: 6.689 ± 3.813
1.115SerHis: 1.115 ± 0.791
1.115SerIle: 1.115 ± 0.636
6.689SerLys: 6.689 ± 2.386
3.344SerLeu: 3.344 ± 1.907
0.0SerMet: 0.0 ± 0.0
4.459SerAsn: 4.459 ± 2.542
2.23SerPro: 2.23 ± 0.156
4.459SerGln: 4.459 ± 2.542
6.689SerArg: 6.689 ± 0.959
3.344SerSer: 3.344 ± 1.907
5.574SerThr: 5.574 ± 1.751
3.344SerVal: 3.344 ± 0.48
1.115SerTrp: 1.115 ± 0.636
2.23SerTyr: 2.23 ± 0.156
0.0SerXaa: 0.0 ± 0.0
Thr
2.23ThrAla: 2.23 ± 1.583
0.0ThrCys: 0.0 ± 0.0
2.23ThrAsp: 2.23 ± 0.156
3.344ThrGlu: 3.344 ± 0.48
3.344ThrPhe: 3.344 ± 0.947
11.148ThrGly: 11.148 ± 2.074
3.344ThrHis: 3.344 ± 0.48
1.115ThrIle: 1.115 ± 0.636
6.689ThrLys: 6.689 ± 0.959
3.344ThrLeu: 3.344 ± 1.907
1.115ThrMet: 1.115 ± 0.636
4.459ThrAsn: 4.459 ± 0.312
1.115ThrPro: 1.115 ± 0.636
3.344ThrGln: 3.344 ± 0.48
1.115ThrArg: 1.115 ± 0.791
6.689ThrSer: 6.689 ± 3.813
3.344ThrThr: 3.344 ± 0.947
3.344ThrVal: 3.344 ± 0.48
1.115ThrTrp: 1.115 ± 0.636
4.459ThrTyr: 4.459 ± 0.312
0.0ThrXaa: 0.0 ± 0.0
Val
1.115ValAla: 1.115 ± 0.636
0.0ValCys: 0.0 ± 0.0
7.804ValAsp: 7.804 ± 2.686
4.459ValGlu: 4.459 ± 1.739
2.23ValPhe: 2.23 ± 1.271
2.23ValGly: 2.23 ± 1.271
1.115ValHis: 1.115 ± 0.791
3.344ValIle: 3.344 ± 0.947
0.0ValLys: 0.0 ± 0.0
2.23ValLeu: 2.23 ± 0.156
1.115ValMet: 1.115 ± 0.636
1.115ValAsn: 1.115 ± 0.636
6.689ValPro: 6.689 ± 1.895
6.689ValGln: 6.689 ± 0.468
3.344ValArg: 3.344 ± 0.48
3.344ValSer: 3.344 ± 0.48
4.459ValThr: 4.459 ± 2.542
2.23ValVal: 2.23 ± 0.156
3.344ValTrp: 3.344 ± 0.947
2.23ValTyr: 2.23 ± 0.156
0.0ValXaa: 0.0 ± 0.0
Trp
3.344TrpAla: 3.344 ± 0.947
0.0TrpCys: 0.0 ± 0.0
1.115TrpAsp: 1.115 ± 0.636
0.0TrpGlu: 0.0 ± 0.0
1.115TrpPhe: 1.115 ± 0.791
1.115TrpGly: 1.115 ± 0.636
0.0TrpHis: 0.0 ± 0.0
1.115TrpIle: 1.115 ± 0.791
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.23TrpAsn: 2.23 ± 0.156
2.23TrpPro: 2.23 ± 0.156
2.23TrpGln: 2.23 ± 1.271
1.115TrpArg: 1.115 ± 0.791
1.115TrpSer: 1.115 ± 0.791
1.115TrpThr: 1.115 ± 0.636
1.115TrpVal: 1.115 ± 0.636
0.0TrpTrp: 0.0 ± 0.0
1.115TrpTyr: 1.115 ± 0.791
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.344TyrAla: 3.344 ± 0.48
2.23TyrCys: 2.23 ± 1.583
5.574TyrAsp: 5.574 ± 1.751
1.115TyrGlu: 1.115 ± 0.791
1.115TyrPhe: 1.115 ± 0.791
1.115TyrGly: 1.115 ± 0.636
0.0TyrHis: 0.0 ± 0.0
1.115TyrIle: 1.115 ± 0.791
4.459TyrLys: 4.459 ± 2.542
4.459TyrLeu: 4.459 ± 0.312
2.23TyrMet: 2.23 ± 1.271
0.0TyrAsn: 0.0 ± 0.0
3.344TyrPro: 3.344 ± 0.947
2.23TyrGln: 2.23 ± 0.156
3.344TyrArg: 3.344 ± 0.947
2.23TyrSer: 2.23 ± 1.271
1.115TyrThr: 1.115 ± 0.791
3.344TyrVal: 3.344 ± 0.947
2.23TyrTrp: 2.23 ± 0.156
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (898 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski