Macaca mulatta papillomavirus 4

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; unclassified Papillomaviridae; primate papillomaviruses

Average proteome isoelectric point is 6.41

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A385AH05|A0A385AH05_9PAPI Replication protein E1 OS=Macaca mulatta papillomavirus 4 OX=2294152 GN=E1 PE=3 SV=1
MM1 pKa = 7.25HH2 pKa = 7.14RR3 pKa = 11.84AKK5 pKa = 10.25RR6 pKa = 11.84VKK8 pKa = 9.98RR9 pKa = 11.84DD10 pKa = 3.35SVQNIYY16 pKa = 9.4NQCKK20 pKa = 9.98ISGNCPEE27 pKa = 4.69DD28 pKa = 3.32VVNKK32 pKa = 10.0VEE34 pKa = 4.09QTTLADD40 pKa = 3.93RR41 pKa = 11.84LLKK44 pKa = 10.35ILGSIVYY51 pKa = 10.01FGGLGIGTGRR61 pKa = 11.84GTGGSTGYY69 pKa = 8.73TPLGAGSGRR78 pKa = 11.84VGAGGTVIRR87 pKa = 11.84PTVPVDD93 pKa = 3.65PIGPVDD99 pKa = 3.97ILPIDD104 pKa = 4.01SVDD107 pKa = 3.56PAASSIVPLSEE118 pKa = 4.63GGLPDD123 pKa = 3.73GAVVEE128 pKa = 4.86LEE130 pKa = 4.27PGGPDD135 pKa = 3.8LGAGDD140 pKa = 4.41IEE142 pKa = 4.85ILTEE146 pKa = 3.89TDD148 pKa = 4.08PISDD152 pKa = 3.4VTGRR156 pKa = 11.84GGHH159 pKa = 6.28PSISTTDD166 pKa = 3.02TDD168 pKa = 3.75VAVIDD173 pKa = 4.14VTPAPAGPRR182 pKa = 11.84RR183 pKa = 11.84TPTFSPIEE191 pKa = 4.14PSHH194 pKa = 7.4VRR196 pKa = 11.84IQASLSTSAEE206 pKa = 3.91PPNINIFIDD215 pKa = 3.73SSLSGQAVSVGEE227 pKa = 4.61EE228 pKa = 4.26IPLQDD233 pKa = 3.67IPLFDD238 pKa = 3.84EE239 pKa = 5.51LEE241 pKa = 4.49IEE243 pKa = 4.43EE244 pKa = 4.75PGPRR248 pKa = 11.84TSTPRR253 pKa = 11.84QVIEE257 pKa = 3.85RR258 pKa = 11.84AYY260 pKa = 8.59TRR262 pKa = 11.84ARR264 pKa = 11.84EE265 pKa = 4.06LYY267 pKa = 8.5NRR269 pKa = 11.84RR270 pKa = 11.84VAQVQTRR277 pKa = 11.84NVDD280 pKa = 3.94FLSRR284 pKa = 11.84PSRR287 pKa = 11.84LVQFEE292 pKa = 4.25FEE294 pKa = 4.2NPAFAEE300 pKa = 4.15EE301 pKa = 4.21DD302 pKa = 3.42VSLAFQQDD310 pKa = 3.65LQQIAAAPDD319 pKa = 3.67ADD321 pKa = 3.95FQDD324 pKa = 4.41VIRR327 pKa = 11.84LGRR330 pKa = 11.84PQLSEE335 pKa = 3.81TGEE338 pKa = 3.75GRR340 pKa = 11.84IRR342 pKa = 11.84YY343 pKa = 8.83SRR345 pKa = 11.84AGRR348 pKa = 11.84RR349 pKa = 11.84GTIRR353 pKa = 11.84TRR355 pKa = 11.84SGVQIGQHH363 pKa = 3.59VHH365 pKa = 6.48FYY367 pKa = 10.88YY368 pKa = 10.83DD369 pKa = 3.76FSTIEE374 pKa = 3.84NADD377 pKa = 4.06AIEE380 pKa = 4.1LQPLGEE386 pKa = 4.26VTGDD390 pKa = 3.35LTLIDD395 pKa = 4.26AQAEE399 pKa = 4.47SSFVDD404 pKa = 3.87SVAVDD409 pKa = 3.44SASEE413 pKa = 4.26HH414 pKa = 6.51IYY416 pKa = 10.84SDD418 pKa = 3.6EE419 pKa = 4.2ALLDD423 pKa = 4.13PYY425 pKa = 11.3VEE427 pKa = 4.61SFDD430 pKa = 4.04NSHH433 pKa = 6.67LVLSVGRR440 pKa = 11.84RR441 pKa = 11.84TDD443 pKa = 2.97SFTVPSIPPGISLKK457 pKa = 10.83VFVDD461 pKa = 4.29DD462 pKa = 4.59YY463 pKa = 11.62GADD466 pKa = 4.17LIVSYY471 pKa = 9.48PQSQDD476 pKa = 2.58HH477 pKa = 7.01TIPHH481 pKa = 6.95PLFPFGPVEE490 pKa = 3.97PVVVFPTSDD499 pKa = 3.05GSDD502 pKa = 3.71YY503 pKa = 11.15LLHH506 pKa = 6.99PSLLKK511 pKa = 9.89RR512 pKa = 11.84RR513 pKa = 11.84RR514 pKa = 11.84RR515 pKa = 11.84KK516 pKa = 9.58RR517 pKa = 11.84RR518 pKa = 11.84YY519 pKa = 9.65SDD521 pKa = 3.18TFF523 pKa = 3.61

Molecular weight: 56.54 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A385AHG8|A0A385AHG8_9PAPI E4 OS=Macaca mulatta papillomavirus 4 OX=2294152 GN=E4 PE=4 SV=1
MM1 pKa = 7.03EE2 pKa = 4.64TLTEE6 pKa = 3.97RR7 pKa = 11.84FEE9 pKa = 4.59TVQEE13 pKa = 4.17ALLKK17 pKa = 10.45LYY19 pKa = 10.27EE20 pKa = 4.47SEE22 pKa = 4.22ATDD25 pKa = 2.95IDD27 pKa = 4.01TQIEE31 pKa = 4.2HH32 pKa = 6.76WNLIRR37 pKa = 11.84KK38 pKa = 8.46EE39 pKa = 4.11NILLHH44 pKa = 5.09YY45 pKa = 9.79ARR47 pKa = 11.84KK48 pKa = 10.2NGVSKK53 pKa = 11.06LGLHH57 pKa = 6.05TVPQLTVSEE66 pKa = 4.85HH67 pKa = 5.53NAKK70 pKa = 9.85QAIKK74 pKa = 9.94MVLLLQKK81 pKa = 10.75LKK83 pKa = 10.77DD84 pKa = 3.57SEE86 pKa = 4.44YY87 pKa = 11.16GKK89 pKa = 10.29EE90 pKa = 3.7RR91 pKa = 11.84WTLTDD96 pKa = 3.08TSLEE100 pKa = 4.15LFNTPPKK107 pKa = 10.67NCLKK111 pKa = 10.76KK112 pKa = 10.87GGFTVDD118 pKa = 3.05VLYY121 pKa = 11.05DD122 pKa = 3.52NEE124 pKa = 4.02EE125 pKa = 4.37SKK127 pKa = 10.84RR128 pKa = 11.84FPYY131 pKa = 9.05TAWTYY136 pKa = 10.84IYY138 pKa = 10.32YY139 pKa = 10.86LNDD142 pKa = 2.91NDD144 pKa = 3.62EE145 pKa = 4.27WEE147 pKa = 4.47KK148 pKa = 11.22VPGKK152 pKa = 10.4ADD154 pKa = 3.47YY155 pKa = 10.82YY156 pKa = 9.77GLYY159 pKa = 10.15YY160 pKa = 10.44EE161 pKa = 4.57EE162 pKa = 5.2SGHH165 pKa = 5.86KK166 pKa = 9.72RR167 pKa = 11.84YY168 pKa = 9.85YY169 pKa = 11.05SKK171 pKa = 11.12FEE173 pKa = 3.96EE174 pKa = 4.93DD175 pKa = 3.0AAQYY179 pKa = 9.6GQTGIWEE186 pKa = 3.96VRR188 pKa = 11.84YY189 pKa = 10.26KK190 pKa = 11.27NNIISAPVTSSTKK203 pKa = 10.58APGSGSAAGVPARR216 pKa = 11.84PTGHH220 pKa = 6.84TEE222 pKa = 3.21TDD224 pKa = 2.95AQTRR228 pKa = 11.84GGRR231 pKa = 11.84RR232 pKa = 11.84KK233 pKa = 9.15VHH235 pKa = 5.99FAPRR239 pKa = 11.84GCTPSTNLSSPLRR252 pKa = 11.84EE253 pKa = 3.73EE254 pKa = 4.13AKK256 pKa = 10.02RR257 pKa = 11.84PRR259 pKa = 11.84GGRR262 pKa = 11.84VGRR265 pKa = 11.84GGQQRR270 pKa = 11.84GQGEE274 pKa = 4.17QGPPQRR280 pKa = 11.84GEE282 pKa = 4.08SPSSKK287 pKa = 9.56RR288 pKa = 11.84RR289 pKa = 11.84RR290 pKa = 11.84IDD292 pKa = 3.12IPDD295 pKa = 3.63SSTGRR300 pKa = 11.84PTFPSPSEE308 pKa = 3.7VGSRR312 pKa = 11.84HH313 pKa = 5.63RR314 pKa = 11.84SVEE317 pKa = 3.69GGHH320 pKa = 6.98RR321 pKa = 11.84SRR323 pKa = 11.84LQQLQDD329 pKa = 3.45EE330 pKa = 4.77ARR332 pKa = 11.84DD333 pKa = 3.76PPVVIIKK340 pKa = 8.65GIPNILKK347 pKa = 9.75CWRR350 pKa = 11.84NRR352 pKa = 11.84TKK354 pKa = 10.65QKK356 pKa = 10.4NSRR359 pKa = 11.84LFTCISSVFTWKK371 pKa = 10.62DD372 pKa = 3.2DD373 pKa = 4.43DD374 pKa = 5.97DD375 pKa = 4.38NACTGSGAKK384 pKa = 10.16GRR386 pKa = 11.84MLVAFDD392 pKa = 3.4TTRR395 pKa = 11.84QRR397 pKa = 11.84DD398 pKa = 3.41IFLKK402 pKa = 9.88TVHH405 pKa = 6.24LPKK408 pKa = 10.09GTSYY412 pKa = 11.27DD413 pKa = 3.39IGSLGSLL420 pKa = 3.72

Molecular weight: 47.34 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2482

94

598

354.6

39.87

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.963 ± 0.313

2.176 ± 0.722

6.326 ± 0.409

6.527 ± 0.614

4.19 ± 0.525

6.487 ± 0.867

1.934 ± 0.248

4.593 ± 0.583

5.479 ± 1.024

9.065 ± 0.931

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.652 ± 0.562

4.069 ± 0.544

6.608 ± 0.702

4.432 ± 0.14

6.205 ± 0.721

7.816 ± 0.571

5.923 ± 0.506

5.761 ± 0.954

1.249 ± 0.312

3.546 ± 0.327
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski