Amino acid dipepetide frequency for endosymbiont of unidentified scaly snail isolate Monju

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.005AlaAla: 13.005 ± 0.192	1.239AlaCys: 1.239 ± 0.044	6.262AlaAsp: 6.262 ± 0.111	8.177AlaGlu: 8.177 ± 0.142	3.509AlaPhe: 3.509 ± 0.081	9.624AlaGly: 9.624 ± 0.166	2.547AlaHis: 2.547 ± 0.066	5.331AlaIle: 5.331 ± 0.109	2.39AlaLys: 2.39 ± 0.08	13.366AlaLeu: 13.366 ± 0.174	2.919AlaMet: 2.919 ± 0.074	2.448AlaAsn: 2.448 ± 0.062	4.584AlaPro: 4.584 ± 0.101	3.829AlaGln: 3.829 ± 0.061	10.104AlaArg: 10.104 ± 0.166	4.627AlaSer: 4.627 ± 0.093	4.535AlaThr: 4.535 ± 0.083	7.58AlaVal: 7.58 ± 0.118	1.826AlaTrp: 1.826 ± 0.054	2.195AlaTyr: 2.195 ± 0.064	0.0AlaXaa: 0.0 ± 0.0
Cys	0.911CysAla: 0.911 ± 0.042	0.171CysCys: 0.171 ± 0.018	0.533CysAsp: 0.533 ± 0.03	0.666CysGlu: 0.666 ± 0.035	0.308CysPhe: 0.308 ± 0.025	1.012CysGly: 1.012 ± 0.045	0.391CysHis: 0.391 ± 0.027	0.44CysIle: 0.44 ± 0.028	0.231CysLys: 0.231 ± 0.019	0.935CysLeu: 0.935 ± 0.037	0.21CysMet: 0.21 ± 0.02	0.264CysAsn: 0.264 ± 0.02	0.66CysPro: 0.66 ± 0.039	0.344CysGln: 0.344 ± 0.022	0.837CysArg: 0.837 ± 0.04	0.488CysSer: 0.488 ± 0.028	0.477CysThr: 0.477 ± 0.025	0.662CysVal: 0.662 ± 0.034	0.124CysTrp: 0.124 ± 0.012	0.255CysTyr: 0.255 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	6.06AspAla: 6.06 ± 0.106	0.614AspCys: 0.614 ± 0.031	3.539AspAsp: 3.539 ± 0.098	4.161AspGlu: 4.161 ± 0.087	2.239AspPhe: 2.239 ± 0.068	4.775AspGly: 4.775 ± 0.118	1.381AspHis: 1.381 ± 0.044	3.091AspIle: 3.091 ± 0.072	1.686AspLys: 1.686 ± 0.064	6.287AspLeu: 6.287 ± 0.114	1.401AspMet: 1.401 ± 0.047	1.376AspAsn: 1.376 ± 0.054	3.8AspPro: 3.8 ± 0.084	1.957AspGln: 1.957 ± 0.056	4.529AspArg: 4.529 ± 0.095	2.368AspSer: 2.368 ± 0.06	2.974AspThr: 2.974 ± 0.113	3.511AspVal: 3.511 ± 0.087	1.188AspTrp: 1.188 ± 0.043	1.754AspTyr: 1.754 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	8.424GluAla: 8.424 ± 0.108	0.511GluCys: 0.511 ± 0.025	3.41GluAsp: 3.41 ± 0.078	4.374GluGlu: 4.374 ± 0.104	1.737GluPhe: 1.737 ± 0.054	5.092GluGly: 5.092 ± 0.094	1.865GluHis: 1.865 ± 0.051	3.82GluIle: 3.82 ± 0.079	2.297GluLys: 2.297 ± 0.08	7.43GluLeu: 7.43 ± 0.115	1.587GluMet: 1.587 ± 0.045	1.655GluAsn: 1.655 ± 0.042	3.011GluPro: 3.011 ± 0.073	3.92GluGln: 3.92 ± 0.098	6.711GluArg: 6.711 ± 0.133	2.564GluSer: 2.564 ± 0.071	3.45GluThr: 3.45 ± 0.079	5.113GluVal: 5.113 ± 0.103	0.799GluTrp: 0.799 ± 0.034	1.417GluTyr: 1.417 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	3.454PheAla: 3.454 ± 0.076	0.367PheCys: 0.367 ± 0.025	2.517PheAsp: 2.517 ± 0.058	2.351PheGlu: 2.351 ± 0.058	1.309PhePhe: 1.309 ± 0.054	2.966PheGly: 2.966 ± 0.079	0.837PheHis: 0.837 ± 0.033	1.463PheIle: 1.463 ± 0.052	0.909PheLys: 0.909 ± 0.04	3.293PheLeu: 3.293 ± 0.076	0.737PheMet: 0.737 ± 0.036	0.943PheAsn: 0.943 ± 0.034	1.48PhePro: 1.48 ± 0.049	0.974PheGln: 0.974 ± 0.035	2.369PheArg: 2.369 ± 0.055	1.925PheSer: 1.925 ± 0.051	1.757PheThr: 1.757 ± 0.05	2.497PheVal: 2.497 ± 0.067	0.55PheTrp: 0.55 ± 0.032	0.919PheTyr: 0.919 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	7.018GlyAla: 7.018 ± 0.109	1.034GlyCys: 1.034 ± 0.05	4.679GlyAsp: 4.679 ± 0.136	6.142GlyGlu: 6.142 ± 0.103	3.077GlyPhe: 3.077 ± 0.068	6.548GlyGly: 6.548 ± 0.172	2.191GlyHis: 2.191 ± 0.058	4.433GlyIle: 4.433 ± 0.078	3.036GlyLys: 3.036 ± 0.078	9.077GlyLeu: 9.077 ± 0.151	2.455GlyMet: 2.455 ± 0.067	2.131GlyAsn: 2.131 ± 0.101	2.921GlyPro: 2.921 ± 0.063	3.048GlyGln: 3.048 ± 0.064	6.471GlyArg: 6.471 ± 0.108	3.887GlySer: 3.887 ± 0.084	3.628GlyThr: 3.628 ± 0.085	6.117GlyVal: 6.117 ± 0.091	1.357GlyTrp: 1.357 ± 0.051	2.191GlyTyr: 2.191 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	2.722HisAla: 2.722 ± 0.073	0.337HisCys: 0.337 ± 0.024	1.462HisAsp: 1.462 ± 0.051	1.541HisGlu: 1.541 ± 0.049	0.993HisPhe: 0.993 ± 0.038	2.152HisGly: 2.152 ± 0.061	0.768HisHis: 0.768 ± 0.039	1.144HisIle: 1.144 ± 0.036	0.705HisLys: 0.705 ± 0.033	2.897HisLeu: 2.897 ± 0.075	0.523HisMet: 0.523 ± 0.029	0.625HisAsn: 0.625 ± 0.032	1.841HisPro: 1.841 ± 0.054	0.895HisGln: 0.895 ± 0.037	2.032HisArg: 2.032 ± 0.065	1.038HisSer: 1.038 ± 0.039	1.068HisThr: 1.068 ± 0.037	1.565HisVal: 1.565 ± 0.043	0.471HisTrp: 0.471 ± 0.029	0.71HisTyr: 0.71 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.891IleAla: 5.891 ± 0.113	0.456IleCys: 0.456 ± 0.025	3.828IleAsp: 3.828 ± 0.069	4.155IleGlu: 4.155 ± 0.088	1.377IlePhe: 1.377 ± 0.048	4.471IleGly: 4.471 ± 0.083	1.126IleHis: 1.126 ± 0.044	1.877IleIle: 1.877 ± 0.056	1.428IleLys: 1.428 ± 0.05	4.453IleLeu: 4.453 ± 0.105	0.782IleMet: 0.782 ± 0.038	1.446IleAsn: 1.446 ± 0.048	2.493IlePro: 2.493 ± 0.064	1.474IleGln: 1.474 ± 0.051	3.693IleArg: 3.693 ± 0.074	2.208IleSer: 2.208 ± 0.063	2.533IleThr: 2.533 ± 0.065	3.427IleVal: 3.427 ± 0.072	0.432IleTrp: 0.432 ± 0.024	1.065IleTyr: 1.065 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	3.259LysAla: 3.259 ± 0.087	0.209LysCys: 0.209 ± 0.017	1.546LysAsp: 1.546 ± 0.064	1.656LysGlu: 1.656 ± 0.062	0.714LysPhe: 0.714 ± 0.033	2.435LysGly: 2.435 ± 0.069	0.628LysHis: 0.628 ± 0.027	1.441LysIle: 1.441 ± 0.052	1.397LysLys: 1.397 ± 0.07	2.835LysLeu: 2.835 ± 0.067	0.659LysMet: 0.659 ± 0.034	0.72LysAsn: 0.72 ± 0.034	1.548LysPro: 1.548 ± 0.057	1.175LysGln: 1.175 ± 0.045	2.339LysArg: 2.339 ± 0.067	1.263LysSer: 1.263 ± 0.047	1.542LysThr: 1.542 ± 0.055	2.437LysVal: 2.437 ± 0.073	0.264LysTrp: 0.264 ± 0.021	0.622LysTyr: 0.622 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	14.324LeuAla: 14.324 ± 0.16	0.993LeuCys: 0.993 ± 0.041	7.193LeuAsp: 7.193 ± 0.132	7.385LeuGlu: 7.385 ± 0.123	3.982LeuPhe: 3.982 ± 0.096	8.967LeuGly: 8.967 ± 0.128	2.873LeuHis: 2.873 ± 0.08	4.865LeuIle: 4.865 ± 0.099	3.19LeuLys: 3.19 ± 0.068	13.297LeuLeu: 13.297 ± 0.244	2.362LeuMet: 2.362 ± 0.059	2.479LeuAsn: 2.479 ± 0.058	6.462LeuPro: 6.462 ± 0.122	3.856LeuGln: 3.856 ± 0.075	9.304LeuArg: 9.304 ± 0.133	5.768LeuSer: 5.768 ± 0.111	4.718LeuThr: 4.718 ± 0.095	8.28LeuVal: 8.28 ± 0.131	1.335LeuTrp: 1.335 ± 0.058	2.441LeuTyr: 2.441 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.729MetAla: 2.729 ± 0.069	0.175MetCys: 0.175 ± 0.016	1.237MetAsp: 1.237 ± 0.043	1.29MetGlu: 1.29 ± 0.048	0.635MetPhe: 0.635 ± 0.03	1.743MetGly: 1.743 ± 0.054	0.532MetHis: 0.532 ± 0.027	1.067MetIle: 1.067 ± 0.045	1.005MetLys: 1.005 ± 0.042	2.449MetLeu: 2.449 ± 0.062	0.55MetMet: 0.55 ± 0.033	0.783MetAsn: 0.783 ± 0.033	1.421MetPro: 1.421 ± 0.05	0.982MetGln: 0.982 ± 0.036	1.841MetArg: 1.841 ± 0.053	1.489MetSer: 1.489 ± 0.048	1.158MetThr: 1.158 ± 0.044	1.587MetVal: 1.587 ± 0.057	0.186MetTrp: 0.186 ± 0.016	0.349MetTyr: 0.349 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.574AsnAla: 2.574 ± 0.069	0.264AsnCys: 0.264 ± 0.023	1.398AsnAsp: 1.398 ± 0.057	1.386AsnGlu: 1.386 ± 0.04	0.8AsnPhe: 0.8 ± 0.033	2.06AsnGly: 2.06 ± 0.073	0.545AsnHis: 0.545 ± 0.029	1.398AsnIle: 1.398 ± 0.048	0.786AsnLys: 0.786 ± 0.034	2.595AsnLeu: 2.595 ± 0.069	0.573AsnMet: 0.573 ± 0.034	0.612AsnAsn: 0.612 ± 0.035	1.743AsnPro: 1.743 ± 0.05	0.804AsnGln: 0.804 ± 0.033	1.937AsnArg: 1.937 ± 0.048	0.969AsnSer: 0.969 ± 0.042	1.237AsnThr: 1.237 ± 0.043	1.53AsnVal: 1.53 ± 0.052	0.339AsnTrp: 0.339 ± 0.022	0.618AsnTyr: 0.618 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	6.004ProAla: 6.004 ± 0.127	0.419ProCys: 0.419 ± 0.024	3.611ProAsp: 3.611 ± 0.088	4.596ProGlu: 4.596 ± 0.084	1.647ProPhe: 1.647 ± 0.055	4.855ProGly: 4.855 ± 0.093	1.156ProHis: 1.156 ± 0.04	1.934ProIle: 1.934 ± 0.051	1.199ProLys: 1.199 ± 0.046	5.585ProLeu: 5.585 ± 0.106	1.103ProMet: 1.103 ± 0.041	1.105ProAsn: 1.105 ± 0.035	3.146ProPro: 3.146 ± 0.097	1.774ProGln: 1.774 ± 0.048	3.386ProArg: 3.386 ± 0.076	2.107ProSer: 2.107 ± 0.052	2.043ProThr: 2.043 ± 0.056	4.522ProVal: 4.522 ± 0.083	0.79ProTrp: 0.79 ± 0.033	1.161ProTyr: 1.161 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	5.277GlnAla: 5.277 ± 0.106	0.282GlnCys: 0.282 ± 0.018	1.625GlnAsp: 1.625 ± 0.05	1.96GlnGlu: 1.96 ± 0.055	1.051GlnPhe: 1.051 ± 0.04	2.983GlnGly: 2.983 ± 0.078	1.013GlnHis: 1.013 ± 0.036	1.826GlnIle: 1.826 ± 0.053	0.991GlnLys: 0.991 ± 0.039	3.987GlnLeu: 3.987 ± 0.084	0.841GlnMet: 0.841 ± 0.035	0.632GlnAsn: 0.632 ± 0.028	1.936GlnPro: 1.936 ± 0.051	1.912GlnGln: 1.912 ± 0.068	3.481GlnArg: 3.481 ± 0.071	1.393GlnSer: 1.393 ± 0.042	1.609GlnThr: 1.609 ± 0.047	3.233GlnVal: 3.233 ± 0.071	0.477GlnTrp: 0.477 ± 0.028	0.787GlnTyr: 0.787 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	7.986ArgAla: 7.986 ± 0.136	0.808ArgCys: 0.808 ± 0.036	4.477ArgAsp: 4.477 ± 0.082	6.68ArgGlu: 6.68 ± 0.115	3.173ArgPhe: 3.173 ± 0.064	5.036ArgGly: 5.036 ± 0.107	2.545ArgHis: 2.545 ± 0.07	4.56ArgIle: 4.56 ± 0.073	2.437ArgLys: 2.437 ± 0.067	10.867ArgLeu: 10.867 ± 0.184	1.913ArgMet: 1.913 ± 0.053	2.022ArgAsn: 2.022 ± 0.058	4.1ArgPro: 4.1 ± 0.083	3.66ArgGln: 3.66 ± 0.083	7.111ArgArg: 7.111 ± 0.147	3.224ArgSer: 3.224 ± 0.074	2.966ArgThr: 2.966 ± 0.064	5.668ArgVal: 5.668 ± 0.108	1.25ArgTrp: 1.25 ± 0.048	2.263ArgTyr: 2.263 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	4.526SerAla: 4.526 ± 0.083	0.473SerCys: 0.473 ± 0.027	2.534SerAsp: 2.534 ± 0.064	2.902SerGlu: 2.902 ± 0.072	1.541SerPhe: 1.541 ± 0.05	4.397SerGly: 4.397 ± 0.096	1.132SerHis: 1.132 ± 0.039	2.143SerIle: 2.143 ± 0.06	1.188SerLys: 1.188 ± 0.047	5.332SerLeu: 5.332 ± 0.117	1.157SerMet: 1.157 ± 0.043	1.099SerAsn: 1.099 ± 0.048	2.444SerPro: 2.444 ± 0.065	1.504SerGln: 1.504 ± 0.057	3.657SerArg: 3.657 ± 0.08	2.205SerSer: 2.205 ± 0.062	2.116SerThr: 2.116 ± 0.061	3.082SerVal: 3.082 ± 0.072	0.587SerTrp: 0.587 ± 0.025	1.034SerTyr: 1.034 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	4.696ThrAla: 4.696 ± 0.091	0.413ThrCys: 0.413 ± 0.026	2.55ThrAsp: 2.55 ± 0.067	2.696ThrGlu: 2.696 ± 0.062	1.514ThrPhe: 1.514 ± 0.045	4.47ThrGly: 4.47 ± 0.101	1.119ThrHis: 1.119 ± 0.038	2.088ThrIle: 2.088 ± 0.058	0.763ThrLys: 0.763 ± 0.037	5.981ThrLeu: 5.981 ± 0.099	0.838ThrMet: 0.838 ± 0.038	0.975ThrAsn: 0.975 ± 0.042	2.993ThrPro: 2.993 ± 0.072	1.222ThrGln: 1.222 ± 0.046	3.496ThrArg: 3.496 ± 0.072	2.068ThrSer: 2.068 ± 0.067	2.276ThrThr: 2.276 ± 0.066	3.479ThrVal: 3.479 ± 0.074	0.673ThrTrp: 0.673 ± 0.032	0.93ThrTyr: 0.93 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	7.913ValAla: 7.913 ± 0.121	0.704ValCys: 0.704 ± 0.034	4.305ValAsp: 4.305 ± 0.102	5.008ValGlu: 5.008 ± 0.093	2.507ValPhe: 2.507 ± 0.061	5.071ValGly: 5.071 ± 0.095	1.717ValHis: 1.717 ± 0.049	4.114ValIle: 4.114 ± 0.082	2.067ValLys: 2.067 ± 0.066	8.354ValLeu: 8.354 ± 0.134	1.853ValMet: 1.853 ± 0.058	1.92ValAsn: 1.92 ± 0.059	3.619ValPro: 3.619 ± 0.073	2.283ValGln: 2.283 ± 0.058	5.748ValArg: 5.748 ± 0.098	3.739ValSer: 3.739 ± 0.073	3.557ValThr: 3.557 ± 0.074	6.083ValVal: 6.083 ± 0.128	0.765ValTrp: 0.765 ± 0.036	1.599ValTyr: 1.599 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.125TrpAla: 1.125 ± 0.051	0.179TrpCys: 0.179 ± 0.015	0.673TrpAsp: 0.673 ± 0.029	0.749TrpGlu: 0.749 ± 0.033	0.552TrpPhe: 0.552 ± 0.029	0.899TrpGly: 0.899 ± 0.042	0.436TrpHis: 0.436 ± 0.024	0.648TrpIle: 0.648 ± 0.03	0.385TrpLys: 0.385 ± 0.025	2.188TrpLeu: 2.188 ± 0.076	0.309TrpMet: 0.309 ± 0.02	0.343TrpAsn: 0.343 ± 0.02	0.708TrpPro: 0.708 ± 0.036	0.734TrpGln: 0.734 ± 0.03	1.339TrpArg: 1.339 ± 0.051	0.635TrpSer: 0.635 ± 0.033	0.528TrpThr: 0.528 ± 0.026	1.002TrpVal: 1.002 ± 0.041	0.261TrpTrp: 0.261 ± 0.022	0.341TrpTyr: 0.341 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.2TyrAla: 2.2 ± 0.065	0.272TyrCys: 0.272 ± 0.023	1.311TyrAsp: 1.311 ± 0.047	1.312TyrGlu: 1.312 ± 0.046	0.95TyrPhe: 0.95 ± 0.043	1.886TyrGly: 1.886 ± 0.059	0.689TyrHis: 0.689 ± 0.034	0.931TyrIle: 0.931 ± 0.042	0.598TyrLys: 0.598 ± 0.032	2.864TyrLeu: 2.864 ± 0.073	0.433TyrMet: 0.433 ± 0.025	0.59TyrAsn: 0.59 ± 0.033	1.232TyrPro: 1.232 ± 0.047	0.948TyrGln: 0.948 ± 0.034	2.362TyrArg: 2.362 ± 0.058	1.089TyrSer: 1.089 ± 0.045	1.071TyrThr: 1.071 ± 0.038	1.553TyrVal: 1.553 ± 0.045	0.36TyrTrp: 0.36 ± 0.022	0.711TyrTyr: 0.711 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2228 proteins (708729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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