Plasmodium falciparum IGH-CR14

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum

Average proteome isoelectric point is 7.15

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5057 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0L1IGS7|A0A0L1IGS7_PLAFA Uncharacterized protein (Fragment) OS=Plasmodium falciparum IGH-CR14 OX=580059 GN=PFMG_04971 PE=4 SV=1
RR1 pKa = 8.14HH2 pKa = 6.23IVVTLTTNEE11 pKa = 3.8FTYY14 pKa = 11.04VDD16 pKa = 4.17SNPNQVDD23 pKa = 3.49DD24 pKa = 4.88TYY26 pKa = 11.89VDD28 pKa = 4.1SNPDD32 pKa = 3.42NSTMDD37 pKa = 4.2TILEE41 pKa = 4.35DD42 pKa = 3.4LDD44 pKa = 4.24KK45 pKa = 11.07PFNEE49 pKa = 4.33PYY51 pKa = 10.47YY52 pKa = 11.06YY53 pKa = 11.16DD54 pKa = 4.13MYY56 pKa = 11.51DD57 pKa = 3.44DD58 pKa = 6.06DD59 pKa = 5.41IYY61 pKa = 11.71YY62 pKa = 10.65DD63 pKa = 4.04VNDD66 pKa = 4.48HH67 pKa = 7.14DD68 pKa = 5.36ASTVDD73 pKa = 3.94SNNMDD78 pKa = 3.38VPSKK82 pKa = 10.76VQIEE86 pKa = 4.17MDD88 pKa = 3.77VNTKK92 pKa = 9.44LVKK95 pKa = 9.89EE96 pKa = 4.57KK97 pKa = 11.31YY98 pKa = 9.73PIADD102 pKa = 2.87VWDD105 pKa = 3.47II106 pKa = 3.77

Molecular weight: 12.39 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0L1IE90|A0A0L1IE90_PLAFA Uncharacterized protein OS=Plasmodium falciparum IGH-CR14 OX=580059 GN=PFMG_03624 PE=4 SV=1
MM1 pKa = 7.71LGPMLVKK8 pKa = 10.66LGPILAKK15 pKa = 10.41LRR17 pKa = 11.84PKK19 pKa = 10.11LVKK22 pKa = 10.28LRR24 pKa = 11.84PQLMNVRR31 pKa = 11.84PMLVKK36 pKa = 10.35VRR38 pKa = 11.84PKK40 pKa = 10.39LVNLRR45 pKa = 11.84PMLVKK50 pKa = 10.46LRR52 pKa = 11.84PMLVKK57 pKa = 10.71LGPILVKK64 pKa = 10.43LRR66 pKa = 11.84PMLVKK71 pKa = 10.41LRR73 pKa = 11.84PMLAKK78 pKa = 10.24LRR80 pKa = 11.84PMLAKK85 pKa = 10.25LRR87 pKa = 11.84PMLVKK92 pKa = 10.3IGPMLVKK99 pKa = 10.29IGAILVKK106 pKa = 10.43VRR108 pKa = 11.84SKK110 pKa = 10.97FSS112 pKa = 3.14

Molecular weight: 12.73 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5057

0

5057

3756975

36

10210

742.9

87.58

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

1.949 ± 0.026

1.768 ± 0.017

6.526 ± 0.034

7.16 ± 0.094

4.253 ± 0.029

2.865 ± 0.035

2.442 ± 0.019

9.192 ± 0.051

11.72 ± 0.046

7.496 ± 0.036

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.196 ± 0.016

14.509 ± 0.111

2.014 ± 0.027

2.762 ± 0.019

2.628 ± 0.021

6.403 ± 0.034

4.11 ± 0.024

3.843 ± 0.055

0.495 ± 0.009

5.67 ± 0.035
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski