Amino acid dipepetide frequency for Blastopirellula cremea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.053AlaAla: 10.053 ± 0.11	1.092AlaCys: 1.092 ± 0.027	5.3AlaAsp: 5.3 ± 0.053	6.815AlaGlu: 6.815 ± 0.077	3.21AlaPhe: 3.21 ± 0.041	6.724AlaGly: 6.724 ± 0.081	1.58AlaHis: 1.58 ± 0.031	5.736AlaIle: 5.736 ± 0.069	4.586AlaLys: 4.586 ± 0.056	8.234AlaLeu: 8.234 ± 0.087	2.598AlaMet: 2.598 ± 0.041	3.358AlaAsn: 3.358 ± 0.05	3.782AlaPro: 3.782 ± 0.053	3.979AlaGln: 3.979 ± 0.053	4.783AlaArg: 4.783 ± 0.057	5.812AlaSer: 5.812 ± 0.064	5.364AlaThr: 5.364 ± 0.058	6.211AlaVal: 6.211 ± 0.06	1.462AlaTrp: 1.462 ± 0.032	2.281AlaTyr: 2.281 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.756CysAla: 0.756 ± 0.023	0.234CysCys: 0.234 ± 0.013	0.659CysAsp: 0.659 ± 0.021	0.62CysGlu: 0.62 ± 0.022	0.489CysPhe: 0.489 ± 0.016	0.992CysGly: 0.992 ± 0.027	0.427CysHis: 0.427 ± 0.02	0.478CysIle: 0.478 ± 0.016	0.317CysLys: 0.317 ± 0.02	1.246CysLeu: 1.246 ± 0.025	0.182CysMet: 0.182 ± 0.011	0.317CysAsn: 0.317 ± 0.013	0.618CysPro: 0.618 ± 0.022	0.54CysGln: 0.54 ± 0.018	0.725CysArg: 0.725 ± 0.02	0.663CysSer: 0.663 ± 0.019	0.486CysThr: 0.486 ± 0.017	0.755CysVal: 0.755 ± 0.023	0.188CysTrp: 0.188 ± 0.01	0.331CysTyr: 0.331 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.03AspAla: 5.03 ± 0.057	0.565AspCys: 0.565 ± 0.019	3.344AspAsp: 3.344 ± 0.051	4.107AspGlu: 4.107 ± 0.046	2.465AspPhe: 2.465 ± 0.039	4.573AspGly: 4.573 ± 0.07	1.34AspHis: 1.34 ± 0.03	2.826AspIle: 2.826 ± 0.043	2.235AspLys: 2.235 ± 0.038	5.733AspLeu: 5.733 ± 0.057	1.135AspMet: 1.135 ± 0.025	1.824AspAsn: 1.824 ± 0.038	3.358AspPro: 3.358 ± 0.048	2.717AspGln: 2.717 ± 0.044	3.47AspArg: 3.47 ± 0.045	3.226AspSer: 3.226 ± 0.053	2.6AspThr: 2.6 ± 0.046	3.825AspVal: 3.825 ± 0.053	1.023AspTrp: 1.023 ± 0.026	1.693AspTyr: 1.693 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.564GluAla: 6.564 ± 0.07	0.493GluCys: 0.493 ± 0.02	3.305GluAsp: 3.305 ± 0.042	4.78GluGlu: 4.78 ± 0.075	2.388GluPhe: 2.388 ± 0.037	4.135GluGly: 4.135 ± 0.061	1.388GluHis: 1.388 ± 0.029	4.11GluIle: 4.11 ± 0.049	3.555GluLys: 3.555 ± 0.052	6.687GluLeu: 6.687 ± 0.064	1.84GluMet: 1.84 ± 0.031	2.426GluAsn: 2.426 ± 0.036	2.791GluPro: 2.791 ± 0.048	3.227GluGln: 3.227 ± 0.046	3.567GluArg: 3.567 ± 0.049	3.726GluSer: 3.726 ± 0.051	3.841GluThr: 3.841 ± 0.051	4.871GluVal: 4.871 ± 0.056	0.698GluTrp: 0.698 ± 0.021	1.568GluTyr: 1.568 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.753PheAla: 3.753 ± 0.047	0.506PheCys: 0.506 ± 0.018	2.696PheAsp: 2.696 ± 0.043	2.282PheGlu: 2.282 ± 0.034	1.576PhePhe: 1.576 ± 0.036	3.219PheGly: 3.219 ± 0.05	0.937PheHis: 0.937 ± 0.023	1.577PheIle: 1.577 ± 0.03	1.105PheLys: 1.105 ± 0.027	3.798PheLeu: 3.798 ± 0.049	0.738PheMet: 0.738 ± 0.02	1.251PheAsn: 1.251 ± 0.029	1.887PhePro: 1.887 ± 0.034	1.655PheGln: 1.655 ± 0.029	2.371PheArg: 2.371 ± 0.039	2.462PheSer: 2.462 ± 0.038	2.088PheThr: 2.088 ± 0.034	2.915PheVal: 2.915 ± 0.043	0.602PheTrp: 0.602 ± 0.022	1.07PheTyr: 1.07 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	5.354GlyAla: 5.354 ± 0.063	1.002GlyCys: 1.002 ± 0.024	4.117GlyAsp: 4.117 ± 0.054	4.7GlyGlu: 4.7 ± 0.062	3.005GlyPhe: 3.005 ± 0.043	5.749GlyGly: 5.749 ± 0.088	1.664GlyHis: 1.664 ± 0.033	4.34GlyIle: 4.34 ± 0.058	4.187GlyLys: 4.187 ± 0.047	6.912GlyLeu: 6.912 ± 0.073	1.977GlyMet: 1.977 ± 0.033	2.901GlyAsn: 2.901 ± 0.045	2.976GlyPro: 2.976 ± 0.045	3.319GlyGln: 3.319 ± 0.043	4.078GlyArg: 4.078 ± 0.049	4.534GlySer: 4.534 ± 0.059	4.349GlyThr: 4.349 ± 0.057	4.94GlyVal: 4.94 ± 0.055	1.256GlyTrp: 1.256 ± 0.029	2.291GlyTyr: 2.291 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.947HisAla: 1.947 ± 0.038	0.322HisCys: 0.322 ± 0.014	1.407HisAsp: 1.407 ± 0.032	1.409HisGlu: 1.409 ± 0.028	1.006HisPhe: 1.006 ± 0.025	1.818HisGly: 1.818 ± 0.036	0.65HisHis: 0.65 ± 0.021	0.939HisIle: 0.939 ± 0.022	0.645HisLys: 0.645 ± 0.016	2.301HisLeu: 2.301 ± 0.042	0.423HisMet: 0.423 ± 0.015	0.701HisAsn: 0.701 ± 0.021	1.38HisPro: 1.38 ± 0.031	0.925HisGln: 0.925 ± 0.023	1.398HisArg: 1.398 ± 0.032	1.216HisSer: 1.216 ± 0.031	0.931HisThr: 0.931 ± 0.021	1.492HisVal: 1.492 ± 0.032	0.467HisTrp: 0.467 ± 0.017	0.678HisTyr: 0.678 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.795IleAla: 5.795 ± 0.058	0.681IleCys: 0.681 ± 0.02	3.839IleAsp: 3.839 ± 0.049	4.06IleGlu: 4.06 ± 0.051	1.796IlePhe: 1.796 ± 0.04	4.235IleGly: 4.235 ± 0.054	1.212IleHis: 1.212 ± 0.025	2.174IleIle: 2.174 ± 0.045	1.729IleLys: 1.729 ± 0.034	4.658IleLeu: 4.658 ± 0.057	0.869IleMet: 0.869 ± 0.023	1.692IleAsn: 1.692 ± 0.031	2.829IlePro: 2.829 ± 0.042	2.105IleGln: 2.105 ± 0.034	3.266IleArg: 3.266 ± 0.045	3.439IleSer: 3.439 ± 0.049	2.934IleThr: 2.934 ± 0.054	4.138IleVal: 4.138 ± 0.053	0.683IleTrp: 0.683 ± 0.02	1.426IleTyr: 1.426 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.492LysAla: 3.492 ± 0.052	0.334LysCys: 0.334 ± 0.014	2.063LysAsp: 2.063 ± 0.038	2.653LysGlu: 2.653 ± 0.05	1.476LysPhe: 1.476 ± 0.029	2.439LysGly: 2.439 ± 0.039	0.93LysHis: 0.93 ± 0.022	2.402LysIle: 2.402 ± 0.037	2.341LysLys: 2.341 ± 0.05	4.612LysLeu: 4.612 ± 0.067	1.132LysMet: 1.132 ± 0.025	1.434LysAsn: 1.434 ± 0.03	2.578LysPro: 2.578 ± 0.044	2.195LysGln: 2.195 ± 0.037	2.539LysArg: 2.539 ± 0.041	2.544LysSer: 2.544 ± 0.04	2.487LysThr: 2.487 ± 0.039	2.904LysVal: 2.904 ± 0.046	0.61LysTrp: 0.61 ± 0.019	1.181LysTyr: 1.181 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	11.217LeuAla: 11.217 ± 0.108	1.122LeuCys: 1.122 ± 0.027	5.524LeuAsp: 5.524 ± 0.052	6.255LeuGlu: 6.255 ± 0.07	3.667LeuPhe: 3.667 ± 0.047	7.383LeuGly: 7.383 ± 0.077	1.999LeuHis: 1.999 ± 0.039	4.944LeuIle: 4.944 ± 0.051	4.311LeuLys: 4.311 ± 0.062	10.425LeuLeu: 10.425 ± 0.101	2.056LeuMet: 2.056 ± 0.033	3.224LeuAsn: 3.224 ± 0.044	5.658LeuPro: 5.658 ± 0.065	3.838LeuGln: 3.838 ± 0.046	5.891LeuArg: 5.891 ± 0.063	6.295LeuSer: 6.295 ± 0.07	5.568LeuThr: 5.568 ± 0.063	7.212LeuVal: 7.212 ± 0.07	1.289LeuTrp: 1.289 ± 0.028	2.175LeuTyr: 2.175 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.291MetAla: 2.291 ± 0.034	0.201MetCys: 0.201 ± 0.01	1.015MetAsp: 1.015 ± 0.027	1.244MetGlu: 1.244 ± 0.027	0.826MetPhe: 0.826 ± 0.022	1.595MetGly: 1.595 ± 0.034	0.464MetHis: 0.464 ± 0.014	1.348MetIle: 1.348 ± 0.031	1.112MetLys: 1.112 ± 0.028	2.521MetLeu: 2.521 ± 0.036	0.589MetMet: 0.589 ± 0.019	0.851MetAsn: 0.851 ± 0.021	1.503MetPro: 1.503 ± 0.033	1.096MetGln: 1.096 ± 0.027	1.393MetArg: 1.393 ± 0.027	1.498MetSer: 1.498 ± 0.026	1.439MetThr: 1.439 ± 0.029	1.667MetVal: 1.667 ± 0.032	0.242MetTrp: 0.242 ± 0.012	0.425MetTyr: 0.425 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.016AsnAla: 3.016 ± 0.046	0.416AsnCys: 0.416 ± 0.016	2.064AsnAsp: 2.064 ± 0.037	2.035AsnGlu: 2.035 ± 0.033	1.333AsnPhe: 1.333 ± 0.03	2.736AsnGly: 2.736 ± 0.048	0.777AsnHis: 0.777 ± 0.023	1.627AsnIle: 1.627 ± 0.03	1.071AsnLys: 1.071 ± 0.027	3.379AsnLeu: 3.379 ± 0.045	0.75AsnMet: 0.75 ± 0.023	1.261AsnAsn: 1.261 ± 0.032	2.152AsnPro: 2.152 ± 0.04	1.65AsnGln: 1.65 ± 0.031	2.243AsnArg: 2.243 ± 0.038	2.072AsnSer: 2.072 ± 0.043	1.737AsnThr: 1.737 ± 0.034	2.36AsnVal: 2.36 ± 0.035	0.656AsnTrp: 0.656 ± 0.022	1.093AsnTyr: 1.093 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	4.893ProAla: 4.893 ± 0.071	0.42ProCys: 0.42 ± 0.017	3.039ProAsp: 3.039 ± 0.046	4.184ProGlu: 4.184 ± 0.057	1.991ProPhe: 1.991 ± 0.037	3.963ProGly: 3.963 ± 0.053	1.153ProHis: 1.153 ± 0.024	2.785ProIle: 2.785 ± 0.045	2.173ProLys: 2.173 ± 0.042	4.793ProLeu: 4.793 ± 0.051	1.132ProMet: 1.132 ± 0.028	2.002ProAsn: 2.002 ± 0.04	2.874ProPro: 2.874 ± 0.051	2.517ProGln: 2.517 ± 0.04	2.418ProArg: 2.418 ± 0.04	3.29ProSer: 3.29 ± 0.048	3.047ProThr: 3.047 ± 0.038	3.621ProVal: 3.621 ± 0.048	0.777ProTrp: 0.777 ± 0.021	1.271ProTyr: 1.271 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.612GlnAla: 4.612 ± 0.054	0.408GlnCys: 0.408 ± 0.016	2.007GlnAsp: 2.007 ± 0.035	2.715GlnGlu: 2.715 ± 0.044	1.707GlnPhe: 1.707 ± 0.03	2.834GlnGly: 2.834 ± 0.038	1.067GlnHis: 1.067 ± 0.026	2.576GlnIle: 2.576 ± 0.04	1.825GlnLys: 1.825 ± 0.03	4.988GlnLeu: 4.988 ± 0.057	1.159GlnMet: 1.159 ± 0.024	1.36GlnAsn: 1.36 ± 0.029	2.601GlnPro: 2.601 ± 0.041	2.85GlnGln: 2.85 ± 0.066	2.982GlnArg: 2.982 ± 0.044	2.469GlnSer: 2.469 ± 0.034	2.471GlnThr: 2.471 ± 0.042	3.035GlnVal: 3.035 ± 0.041	0.709GlnTrp: 0.709 ± 0.019	1.108GlnTyr: 1.108 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	4.027ArgAla: 4.027 ± 0.046	0.626ArgCys: 0.626 ± 0.021	3.255ArgAsp: 3.255 ± 0.044	3.949ArgGlu: 3.949 ± 0.049	2.588ArgPhe: 2.588 ± 0.042	3.743ArgGly: 3.743 ± 0.053	1.384ArgHis: 1.384 ± 0.027	3.429ArgIle: 3.429 ± 0.049	2.567ArgLys: 2.567 ± 0.04	6.367ArgLeu: 6.367 ± 0.076	1.602ArgMet: 1.602 ± 0.033	2.063ArgAsn: 2.063 ± 0.035	2.768ArgPro: 2.768 ± 0.044	2.95ArgGln: 2.95 ± 0.041	4.225ArgArg: 4.225 ± 0.061	3.489ArgSer: 3.489 ± 0.046	2.922ArgThr: 2.922 ± 0.042	3.779ArgVal: 3.779 ± 0.048	1.053ArgTrp: 1.053 ± 0.026	1.836ArgTyr: 1.836 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	5.023SerAla: 5.023 ± 0.064	0.598SerCys: 0.598 ± 0.019	3.52SerAsp: 3.52 ± 0.052	3.836SerGlu: 3.836 ± 0.05	2.379SerPhe: 2.379 ± 0.037	5.145SerGly: 5.145 ± 0.063	1.379SerHis: 1.379 ± 0.029	3.203SerIle: 3.203 ± 0.048	2.227SerLys: 2.227 ± 0.041	6.438SerLeu: 6.438 ± 0.073	1.465SerMet: 1.465 ± 0.027	2.111SerAsn: 2.111 ± 0.039	3.703SerPro: 3.703 ± 0.05	2.85SerGln: 2.85 ± 0.044	3.488SerArg: 3.488 ± 0.038	4.296SerSer: 4.296 ± 0.069	3.232SerThr: 3.232 ± 0.043	4.035SerVal: 4.035 ± 0.054	0.946SerTrp: 0.946 ± 0.022	1.615SerTyr: 1.615 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	4.922ThrAla: 4.922 ± 0.057	0.594ThrCys: 0.594 ± 0.019	3.065ThrAsp: 3.065 ± 0.053	3.081ThrGlu: 3.081 ± 0.046	2.208ThrPhe: 2.208 ± 0.034	4.293ThrGly: 4.293 ± 0.057	1.151ThrHis: 1.151 ± 0.026	3.326ThrIle: 3.326 ± 0.047	2.255ThrLys: 2.255 ± 0.044	5.563ThrLeu: 5.563 ± 0.058	1.215ThrMet: 1.215 ± 0.028	1.949ThrAsn: 1.949 ± 0.048	3.306ThrPro: 3.306 ± 0.045	2.127ThrGln: 2.127 ± 0.029	2.696ThrArg: 2.696 ± 0.045	3.698ThrSer: 3.698 ± 0.051	3.295ThrThr: 3.295 ± 0.052	3.881ThrVal: 3.881 ± 0.048	0.867ThrTrp: 0.867 ± 0.023	1.559ThrTyr: 1.559 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	6.883ValAla: 6.883 ± 0.069	0.861ValCys: 0.861 ± 0.029	4.247ValAsp: 4.247 ± 0.055	4.741ValGlu: 4.741 ± 0.06	2.535ValPhe: 2.535 ± 0.037	4.946ValGly: 4.946 ± 0.059	1.401ValHis: 1.401 ± 0.028	3.876ValIle: 3.876 ± 0.05	2.575ValLys: 2.575 ± 0.042	6.846ValLeu: 6.846 ± 0.077	1.616ValMet: 1.616 ± 0.031	2.207ValAsn: 2.207 ± 0.046	3.549ValPro: 3.549 ± 0.048	2.583ValGln: 2.583 ± 0.036	4.22ValArg: 4.22 ± 0.047	4.31ValSer: 4.31 ± 0.054	4.185ValThr: 4.185 ± 0.052	5.698ValVal: 5.698 ± 0.07	1.017ValTrp: 1.017 ± 0.028	1.747ValTyr: 1.747 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.126TrpAla: 1.126 ± 0.027	0.175TrpCys: 0.175 ± 0.01	0.8TrpAsp: 0.8 ± 0.02	0.84TrpGlu: 0.84 ± 0.026	0.62TrpPhe: 0.62 ± 0.02	1.031TrpGly: 1.031 ± 0.023	0.417TrpHis: 0.417 ± 0.017	0.845TrpIle: 0.845 ± 0.02	0.782TrpLys: 0.782 ± 0.023	1.715TrpLeu: 1.715 ± 0.037	0.384TrpMet: 0.384 ± 0.014	0.654TrpAsn: 0.654 ± 0.019	0.704TrpPro: 0.704 ± 0.021	0.93TrpGln: 0.93 ± 0.026	0.94TrpArg: 0.94 ± 0.023	0.923TrpSer: 0.923 ± 0.026	0.798TrpThr: 0.798 ± 0.022	0.929TrpVal: 0.929 ± 0.021	0.299TrpTrp: 0.299 ± 0.014	0.411TrpTyr: 0.411 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.207TyrAla: 2.207 ± 0.035	0.372TyrCys: 0.372 ± 0.015	1.825TyrAsp: 1.825 ± 0.043	1.652TyrGlu: 1.652 ± 0.029	1.223TyrPhe: 1.223 ± 0.028	2.099TyrGly: 2.099 ± 0.033	0.735TyrHis: 0.735 ± 0.023	1.016TyrIle: 1.016 ± 0.024	0.748TyrLys: 0.748 ± 0.023	2.836TyrLeu: 2.836 ± 0.04	0.454TyrMet: 0.454 ± 0.017	0.845TyrAsn: 0.845 ± 0.025	1.329TyrPro: 1.329 ± 0.029	1.427TyrGln: 1.427 ± 0.031	1.929TyrArg: 1.929 ± 0.033	1.529TyrSer: 1.529 ± 0.03	1.28TyrThr: 1.28 ± 0.039	1.777TyrVal: 1.777 ± 0.033	0.478TyrTrp: 0.478 ± 0.019	0.949TyrTyr: 0.949 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5042 proteins (1789957 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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