Amino acid dipepetide frequency for Candidatus Kinetoplastibacterium blastocrithidii TCC012E

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.09AlaAla: 4.09 ± 0.179
0.843AlaCys: 0.843 ± 0.065
2.882AlaAsp: 2.882 ± 0.115
2.753AlaGlu: 2.753 ± 0.105
2.304AlaPhe: 2.304 ± 0.102
3.691AlaGly: 3.691 ± 0.152
1.163AlaHis: 1.163 ± 0.081
6.108AlaIle: 6.108 ± 0.175
3.741AlaLys: 3.741 ± 0.133
5.747AlaLeu: 5.747 ± 0.199
1.628AlaMet: 1.628 ± 0.087
2.99AlaAsn: 2.99 ± 0.115
1.711AlaPro: 1.711 ± 0.09
1.628AlaGln: 1.628 ± 0.092
3.081AlaArg: 3.081 ± 0.125
4.509AlaSer: 4.509 ± 0.149
2.587AlaThr: 2.587 ± 0.113
3.546AlaVal: 3.546 ± 0.152
0.552AlaTrp: 0.552 ± 0.048
1.765AlaTyr: 1.765 ± 0.087
0.0AlaXaa: 0.0 ± 0.0
Cys
0.689CysAla: 0.689 ± 0.06
0.183CysCys: 0.183 ± 0.027
0.776CysAsp: 0.776 ± 0.07
0.59CysGlu: 0.59 ± 0.046
0.764CysPhe: 0.764 ± 0.048
1.05CysGly: 1.05 ± 0.068
0.257CysHis: 0.257 ± 0.032
1.325CysIle: 1.325 ± 0.072
0.864CysLys: 0.864 ± 0.069
1.312CysLeu: 1.312 ± 0.08
0.237CysMet: 0.237 ± 0.03
0.88CysAsn: 0.88 ± 0.066
0.477CysPro: 0.477 ± 0.047
0.262CysGln: 0.262 ± 0.033
0.519CysArg: 0.519 ± 0.049
1.088CysSer: 1.088 ± 0.067
0.527CysThr: 0.527 ± 0.048
0.689CysVal: 0.689 ± 0.058
0.12CysTrp: 0.12 ± 0.024
0.465CysTyr: 0.465 ± 0.046
0.0CysXaa: 0.0 ± 0.0
Asp
2.99AspAla: 2.99 ± 0.129
0.868AspCys: 0.868 ± 0.069
3.035AspAsp: 3.035 ± 0.119
2.836AspGlu: 2.836 ± 0.124
2.965AspPhe: 2.965 ± 0.132
3.284AspGly: 3.284 ± 0.134
1.08AspHis: 1.08 ± 0.071
6.776AspIle: 6.776 ± 0.176
3.87AspLys: 3.87 ± 0.141
6.025AspLeu: 6.025 ± 0.171
1.325AspMet: 1.325 ± 0.083
3.587AspAsn: 3.587 ± 0.117
1.964AspPro: 1.964 ± 0.09
1.408AspGln: 1.408 ± 0.081
2.736AspArg: 2.736 ± 0.112
4.746AspSer: 4.746 ± 0.162
2.437AspThr: 2.437 ± 0.101
3.434AspVal: 3.434 ± 0.128
0.577AspTrp: 0.577 ± 0.056
2.022AspTyr: 2.022 ± 0.082
0.0AspXaa: 0.0 ± 0.0
Glu
3.488GluAla: 3.488 ± 0.124
0.598GluCys: 0.598 ± 0.053
2.778GluAsp: 2.778 ± 0.121
3.347GluGlu: 3.347 ± 0.147
2.404GluPhe: 2.404 ± 0.116
2.545GluGly: 2.545 ± 0.101
1.038GluHis: 1.038 ± 0.063
6.519GluIle: 6.519 ± 0.184
4.376GluLys: 4.376 ± 0.156
5.389GluLeu: 5.389 ± 0.162
1.399GluMet: 1.399 ± 0.079
3.778GluAsn: 3.778 ± 0.122
1.437GluPro: 1.437 ± 0.085
1.677GluGln: 1.677 ± 0.089
2.649GluArg: 2.649 ± 0.121
4.115GluSer: 4.115 ± 0.111
2.5GluThr: 2.5 ± 0.11
3.122GluVal: 3.122 ± 0.139
0.631GluTrp: 0.631 ± 0.051
2.151GluTyr: 2.151 ± 0.093
0.0GluXaa: 0.0 ± 0.0
Phe
2.246PheAla: 2.246 ± 0.122
0.585PheCys: 0.585 ± 0.052
2.886PheAsp: 2.886 ± 0.101
2.3PheGlu: 2.3 ± 0.106
2.172PhePhe: 2.172 ± 0.111
2.948PheGly: 2.948 ± 0.101
0.868PheHis: 0.868 ± 0.058
4.596PheIle: 4.596 ± 0.174
2.475PheLys: 2.475 ± 0.104
4.625PheLeu: 4.625 ± 0.161
0.997PheMet: 0.997 ± 0.058
2.471PheAsn: 2.471 ± 0.109
1.42PhePro: 1.42 ± 0.072
1.03PheGln: 1.03 ± 0.069
1.86PheArg: 1.86 ± 0.093
4.198PheSer: 4.198 ± 0.151
1.623PheThr: 1.623 ± 0.082
2.338PheVal: 2.338 ± 0.102
0.386PheTrp: 0.386 ± 0.047
1.636PheTyr: 1.636 ± 0.083
0.0PheXaa: 0.0 ± 0.0
Gly
3.828GlyAla: 3.828 ± 0.145
0.897GlyCys: 0.897 ± 0.058
3.164GlyAsp: 3.164 ± 0.118
3.081GlyGlu: 3.081 ± 0.127
3.081GlyPhe: 3.081 ± 0.113
4.148GlyGly: 4.148 ± 0.152
1.432GlyHis: 1.432 ± 0.077
6.614GlyIle: 6.614 ± 0.199
4.418GlyLys: 4.418 ± 0.135
5.917GlyLeu: 5.917 ± 0.148
1.698GlyMet: 1.698 ± 0.077
3.048GlyAsn: 3.048 ± 0.124
1.702GlyPro: 1.702 ± 0.09
1.511GlyGln: 1.511 ± 0.079
2.99GlyArg: 2.99 ± 0.126
5.016GlySer: 5.016 ± 0.179
2.79GlyThr: 2.79 ± 0.116
4.065GlyVal: 4.065 ± 0.151
0.577GlyTrp: 0.577 ± 0.053
2.109GlyTyr: 2.109 ± 0.092
0.0GlyXaa: 0.0 ± 0.0
His
1.167HisAla: 1.167 ± 0.064
0.262HisCys: 0.262 ± 0.037
1.088HisAsp: 1.088 ± 0.075
0.98HisGlu: 0.98 ± 0.058
0.756HisPhe: 0.756 ± 0.056
1.54HisGly: 1.54 ± 0.089
0.345HisHis: 0.345 ± 0.038
1.989HisIle: 1.989 ± 0.073
1.208HisLys: 1.208 ± 0.078
1.74HisLeu: 1.74 ± 0.088
0.469HisMet: 0.469 ± 0.044
1.229HisAsn: 1.229 ± 0.078
0.901HisPro: 0.901 ± 0.067
0.473HisGln: 0.473 ± 0.048
0.984HisArg: 0.984 ± 0.067
1.507HisSer: 1.507 ± 0.086
0.772HisThr: 0.772 ± 0.051
1.096HisVal: 1.096 ± 0.069
0.154HisTrp: 0.154 ± 0.027
0.681HisTyr: 0.681 ± 0.053
0.0HisXaa: 0.0 ± 0.0
Ile
6.361IleAla: 6.361 ± 0.187
1.37IleCys: 1.37 ± 0.078
7.378IleAsp: 7.378 ± 0.164
6.573IleGlu: 6.573 ± 0.192
3.878IlePhe: 3.878 ± 0.151
6.544IleGly: 6.544 ± 0.172
1.661IleHis: 1.661 ± 0.085
8.711IleIle: 8.711 ± 0.235
7.349IleLys: 7.349 ± 0.187
9.072IleLeu: 9.072 ± 0.22
2.176IleMet: 2.176 ± 0.114
7.137IleAsn: 7.137 ± 0.212
3.467IlePro: 3.467 ± 0.11
2.23IleGln: 2.23 ± 0.101
4.227IleArg: 4.227 ± 0.13
9.139IleSer: 9.139 ± 0.219
4.484IleThr: 4.484 ± 0.16
6.415IleVal: 6.415 ± 0.142
0.727IleTrp: 0.727 ± 0.05
2.944IleTyr: 2.944 ± 0.127
0.0IleXaa: 0.0 ± 0.0
Lys
3.297LysAla: 3.297 ± 0.145
0.615LysCys: 0.615 ± 0.06
3.861LysAsp: 3.861 ± 0.13
4.455LysGlu: 4.455 ± 0.146
2.728LysPhe: 2.728 ± 0.104
3.097LysGly: 3.097 ± 0.126
1.391LysHis: 1.391 ± 0.078
7.312LysIle: 7.312 ± 0.211
5.722LysLys: 5.722 ± 0.218
6.664LysLeu: 6.664 ± 0.177
1.702LysMet: 1.702 ± 0.088
5.813LysAsn: 5.813 ± 0.158
1.976LysPro: 1.976 ± 0.091
2.068LysGln: 2.068 ± 0.106
2.948LysArg: 2.948 ± 0.119
5.622LysSer: 5.622 ± 0.164
3.463LysThr: 3.463 ± 0.121
3.629LysVal: 3.629 ± 0.11
0.706LysTrp: 0.706 ± 0.064
2.421LysTyr: 2.421 ± 0.119
0.0LysXaa: 0.0 ± 0.0
Leu
5.996LeuAla: 5.996 ± 0.192
1.291LeuCys: 1.291 ± 0.071
5.925LeuAsp: 5.925 ± 0.161
5.647LeuGlu: 5.647 ± 0.152
4.073LeuPhe: 4.073 ± 0.143
5.888LeuGly: 5.888 ± 0.175
1.893LeuHis: 1.893 ± 0.081
8.508LeuIle: 8.508 ± 0.207
6.415LeuLys: 6.415 ± 0.167
9.434LeuLeu: 9.434 ± 0.242
2.288LeuMet: 2.288 ± 0.097
5.601LeuAsn: 5.601 ± 0.159
3.895LeuPro: 3.895 ± 0.109
2.599LeuGln: 2.599 ± 0.111
5.165LeuArg: 5.165 ± 0.166
9.334LeuSer: 9.334 ± 0.232
3.957LeuThr: 3.957 ± 0.14
5.813LeuVal: 5.813 ± 0.178
0.814LeuTrp: 0.814 ± 0.064
2.96LeuTyr: 2.96 ± 0.103
0.0LeuXaa: 0.0 ± 0.0
Met
1.594MetAla: 1.594 ± 0.087
0.203MetCys: 0.203 ± 0.026
1.188MetAsp: 1.188 ± 0.071
1.208MetGlu: 1.208 ± 0.068
0.839MetPhe: 0.839 ± 0.067
1.536MetGly: 1.536 ± 0.084
0.519MetHis: 0.519 ± 0.053
2.147MetIle: 2.147 ± 0.092
1.503MetLys: 1.503 ± 0.086
2.703MetLeu: 2.703 ± 0.111
0.619MetMet: 0.619 ± 0.064
1.462MetAsn: 1.462 ± 0.077
1.059MetPro: 1.059 ± 0.079
0.793MetGln: 0.793 ± 0.05
1.341MetArg: 1.341 ± 0.087
2.047MetSer: 2.047 ± 0.081
1.125MetThr: 1.125 ± 0.067
1.383MetVal: 1.383 ± 0.094
0.104MetTrp: 0.104 ± 0.022
0.623MetTyr: 0.623 ± 0.047
0.0MetXaa: 0.0 ± 0.0
Asn
2.79AsnAla: 2.79 ± 0.112
0.83AsnCys: 0.83 ± 0.058
3.529AsnAsp: 3.529 ± 0.129
3.11AsnGlu: 3.11 ± 0.113
2.761AsnPhe: 2.761 ± 0.116
3.803AsnGly: 3.803 ± 0.126
1.237AsnHis: 1.237 ± 0.073
7.706AsnIle: 7.706 ± 0.203
5.107AsnLys: 5.107 ± 0.176
5.763AsnLeu: 5.763 ± 0.19
1.47AsnMet: 1.47 ± 0.071
5.24AsnAsn: 5.24 ± 0.191
2.242AsnPro: 2.242 ± 0.094
1.532AsnGln: 1.532 ± 0.096
2.931AsnArg: 2.931 ± 0.118
4.933AsnSer: 4.933 ± 0.155
2.549AsnThr: 2.549 ± 0.101
3.359AsnVal: 3.359 ± 0.131
0.552AsnTrp: 0.552 ± 0.057
2.159AsnTyr: 2.159 ± 0.1
0.0AsnXaa: 0.0 ± 0.0
Pro
1.611ProAla: 1.611 ± 0.087
0.477ProCys: 0.477 ± 0.048
2.005ProAsp: 2.005 ± 0.085
2.296ProGlu: 2.296 ± 0.102
1.582ProPhe: 1.582 ± 0.083
2.404ProGly: 2.404 ± 0.091
0.685ProHis: 0.685 ± 0.045
3.176ProIle: 3.176 ± 0.114
1.951ProLys: 1.951 ± 0.081
3.06ProLeu: 3.06 ± 0.125
0.768ProMet: 0.768 ± 0.06
1.96ProAsn: 1.96 ± 0.082
0.785ProPro: 0.785 ± 0.063
0.735ProGln: 0.735 ± 0.056
1.258ProArg: 1.258 ± 0.071
2.603ProSer: 2.603 ± 0.099
1.545ProThr: 1.545 ± 0.082
2.313ProVal: 2.313 ± 0.112
0.39ProTrp: 0.39 ± 0.045
1.283ProTyr: 1.283 ± 0.07
0.0ProXaa: 0.0 ± 0.0
Gln
1.682GlnAla: 1.682 ± 0.094
0.336GlnCys: 0.336 ± 0.037
1.416GlnAsp: 1.416 ± 0.087
1.594GlnGlu: 1.594 ± 0.091
1.067GlnPhe: 1.067 ± 0.065
1.374GlnGly: 1.374 ± 0.07
0.536GlnHis: 0.536 ± 0.05
2.558GlnIle: 2.558 ± 0.109
2.03GlnLys: 2.03 ± 0.084
2.346GlnLeu: 2.346 ± 0.116
0.718GlnMet: 0.718 ± 0.057
1.412GlnAsn: 1.412 ± 0.08
0.673GlnPro: 0.673 ± 0.055
0.706GlnGln: 0.706 ± 0.056
1.246GlnArg: 1.246 ± 0.071
1.848GlnSer: 1.848 ± 0.089
1.109GlnThr: 1.109 ± 0.07
1.619GlnVal: 1.619 ± 0.088
0.328GlnTrp: 0.328 ± 0.034
0.814GlnTyr: 0.814 ± 0.06
0.0GlnXaa: 0.0 ± 0.0
Arg
2.686ArgAla: 2.686 ± 0.106
0.54ArgCys: 0.54 ± 0.05
2.616ArgAsp: 2.616 ± 0.112
2.886ArgGlu: 2.886 ± 0.1
2.138ArgPhe: 2.138 ± 0.099
2.612ArgGly: 2.612 ± 0.112
0.884ArgHis: 0.884 ± 0.063
4.659ArgIle: 4.659 ± 0.136
3.168ArgLys: 3.168 ± 0.105
4.538ArgLeu: 4.538 ± 0.141
1.233ArgMet: 1.233 ± 0.073
2.94ArgAsn: 2.94 ± 0.119
1.491ArgPro: 1.491 ± 0.094
1.437ArgGln: 1.437 ± 0.085
2.512ArgArg: 2.512 ± 0.107
3.783ArgSer: 3.783 ± 0.121
2.022ArgThr: 2.022 ± 0.101
3.027ArgVal: 3.027 ± 0.117
0.37ArgTrp: 0.37 ± 0.039
1.794ArgTyr: 1.794 ± 0.079
0.0ArgXaa: 0.0 ± 0.0
Ser
4.293SerAla: 4.293 ± 0.178
1.192SerCys: 1.192 ± 0.065
4.895SerAsp: 4.895 ± 0.143
4.534SerGlu: 4.534 ± 0.146
3.974SerPhe: 3.974 ± 0.131
5.751SerGly: 5.751 ± 0.184
1.486SerHis: 1.486 ± 0.079
8.952SerIle: 8.952 ± 0.244
5.693SerLys: 5.693 ± 0.146
8.69SerLeu: 8.69 ± 0.232
1.914SerMet: 1.914 ± 0.09
5.344SerAsn: 5.344 ± 0.173
2.441SerPro: 2.441 ± 0.111
1.914SerGln: 1.914 ± 0.088
3.899SerArg: 3.899 ± 0.127
7.117SerSer: 7.117 ± 0.197
3.114SerThr: 3.114 ± 0.104
4.783SerVal: 4.783 ± 0.173
0.843SerTrp: 0.843 ± 0.067
2.799SerTyr: 2.799 ± 0.107
0.0SerXaa: 0.0 ± 0.0
Thr
2.537ThrAla: 2.537 ± 0.115
0.561ThrCys: 0.561 ± 0.05
2.471ThrAsp: 2.471 ± 0.108
2.363ThrGlu: 2.363 ± 0.101
1.424ThrPhe: 1.424 ± 0.08
3.181ThrGly: 3.181 ± 0.121
0.901ThrHis: 0.901 ± 0.062
4.472ThrIle: 4.472 ± 0.17
2.778ThrLys: 2.778 ± 0.108
4.036ThrLeu: 4.036 ± 0.15
0.976ThrMet: 0.976 ± 0.072
2.686ThrAsn: 2.686 ± 0.112
1.719ThrPro: 1.719 ± 0.095
0.897ThrGln: 0.897 ± 0.058
2.072ThrArg: 2.072 ± 0.098
3.347ThrSer: 3.347 ± 0.129
2.109ThrThr: 2.109 ± 0.1
2.815ThrVal: 2.815 ± 0.125
0.432ThrTrp: 0.432 ± 0.042
1.217ThrTyr: 1.217 ± 0.071
0.0ThrXaa: 0.0 ± 0.0
Val
3.741ValAla: 3.741 ± 0.165
0.835ValCys: 0.835 ± 0.06
3.758ValAsp: 3.758 ± 0.139
3.309ValGlu: 3.309 ± 0.127
2.811ValPhe: 2.811 ± 0.126
3.832ValGly: 3.832 ± 0.144
1.142ValHis: 1.142 ± 0.076
5.626ValIle: 5.626 ± 0.164
3.538ValLys: 3.538 ± 0.136
6.045ValLeu: 6.045 ± 0.181
1.412ValMet: 1.412 ± 0.081
3.376ValAsn: 3.376 ± 0.115
2.13ValPro: 2.13 ± 0.105
1.354ValGln: 1.354 ± 0.073
2.807ValArg: 2.807 ± 0.126
5.261ValSer: 5.261 ± 0.18
2.703ValThr: 2.703 ± 0.101
4.156ValVal: 4.156 ± 0.141
0.482ValTrp: 0.482 ± 0.044
1.59ValTyr: 1.59 ± 0.083
0.0ValXaa: 0.0 ± 0.0
Trp
0.419TrpAla: 0.419 ± 0.045
0.133TrpCys: 0.133 ± 0.023
0.511TrpAsp: 0.511 ± 0.045
0.44TrpGlu: 0.44 ± 0.042
0.461TrpPhe: 0.461 ± 0.049
0.419TrpGly: 0.419 ± 0.039
0.249TrpHis: 0.249 ± 0.041
0.984TrpIle: 0.984 ± 0.073
0.648TrpLys: 0.648 ± 0.044
1.258TrpLeu: 1.258 ± 0.07
0.27TrpMet: 0.27 ± 0.035
0.552TrpAsn: 0.552 ± 0.051
0.32TrpPro: 0.32 ± 0.033
0.307TrpGln: 0.307 ± 0.032
0.523TrpArg: 0.523 ± 0.05
0.602TrpSer: 0.602 ± 0.048
0.27TrpThr: 0.27 ± 0.037
0.498TrpVal: 0.498 ± 0.046
0.083TrpTrp: 0.083 ± 0.02
0.249TrpTyr: 0.249 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.81TyrAla: 1.81 ± 0.089
0.457TyrCys: 0.457 ± 0.045
1.802TyrAsp: 1.802 ± 0.084
1.64TyrGlu: 1.64 ± 0.091
1.478TyrPhe: 1.478 ± 0.08
2.437TyrGly: 2.437 ± 0.117
0.573TyrHis: 0.573 ± 0.044
3.106TyrIle: 3.106 ± 0.12
2.641TyrLys: 2.641 ± 0.111
3.131TyrLeu: 3.131 ± 0.109
0.693TyrMet: 0.693 ± 0.051
2.101TyrAsn: 2.101 ± 0.104
1.08TyrPro: 1.08 ± 0.06
0.851TyrGln: 0.851 ± 0.058
1.586TyrArg: 1.586 ± 0.082
2.815TyrSer: 2.815 ± 0.12
1.304TyrThr: 1.304 ± 0.089
1.806TyrVal: 1.806 ± 0.095
0.37TyrTrp: 0.37 ± 0.037
1.15TyrTyr: 1.15 ± 0.08
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 723 proteins (240842 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski