Amino acid dipepetide frequency for Chayote yellow mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.277AlaAla: 10.277 ± 3.311
1.028AlaCys: 1.028 ± 0.969
3.083AlaAsp: 3.083 ± 0.935
3.083AlaGlu: 3.083 ± 1.51
1.028AlaPhe: 1.028 ± 0.774
1.028AlaGly: 1.028 ± 0.774
3.083AlaHis: 3.083 ± 2.49
4.111AlaIle: 4.111 ± 1.309
4.111AlaLys: 4.111 ± 1.174
8.222AlaLeu: 8.222 ± 2.725
0.0AlaMet: 0.0 ± 0.0
4.111AlaAsn: 4.111 ± 2.124
2.055AlaPro: 2.055 ± 1.549
3.083AlaGln: 3.083 ± 1.702
4.111AlaArg: 4.111 ± 2.136
6.166AlaSer: 6.166 ± 1.306
1.028AlaThr: 1.028 ± 0.969
3.083AlaVal: 3.083 ± 1.482
2.055AlaTrp: 2.055 ± 1.549
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
3.083CysAla: 3.083 ± 2.099
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.028CysGlu: 1.028 ± 0.969
1.028CysPhe: 1.028 ± 1.131
2.055CysGly: 2.055 ± 1.093
1.028CysHis: 1.028 ± 0.774
1.028CysIle: 1.028 ± 0.969
2.055CysLys: 2.055 ± 1.939
2.055CysLeu: 2.055 ± 1.939
1.028CysMet: 1.028 ± 1.216
1.028CysAsn: 1.028 ± 0.774
0.0CysPro: 0.0 ± 0.0
1.028CysGln: 1.028 ± 0.774
1.028CysArg: 1.028 ± 0.774
3.083CysSer: 3.083 ± 1.51
2.055CysThr: 2.055 ± 0.831
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.055AspAla: 2.055 ± 1.549
1.028AspCys: 1.028 ± 1.144
2.055AspAsp: 2.055 ± 1.093
3.083AspGlu: 3.083 ± 1.281
1.028AspPhe: 1.028 ± 0.969
3.083AspGly: 3.083 ± 2.323
1.028AspHis: 1.028 ± 1.131
2.055AspIle: 2.055 ± 1.189
4.111AspLys: 4.111 ± 1.054
5.139AspLeu: 5.139 ± 2.247
1.028AspMet: 1.028 ± 0.671
1.028AspAsn: 1.028 ± 0.969
1.028AspPro: 1.028 ± 0.774
3.083AspGln: 3.083 ± 1.102
2.055AspArg: 2.055 ± 1.939
9.25AspSer: 9.25 ± 1.954
0.0AspThr: 0.0 ± 0.0
7.194AspVal: 7.194 ± 1.784
2.055AspTrp: 2.055 ± 1.093
1.028AspTyr: 1.028 ± 0.774
0.0AspXaa: 0.0 ± 0.0
Glu
7.194GluAla: 7.194 ± 1.228
1.028GluCys: 1.028 ± 1.144
2.055GluAsp: 2.055 ± 1.549
3.083GluGlu: 3.083 ± 2.323
3.083GluPhe: 3.083 ± 1.51
3.083GluGly: 3.083 ± 1.281
0.0GluHis: 0.0 ± 0.0
1.028GluIle: 1.028 ± 1.131
2.055GluLys: 2.055 ± 1.549
6.166GluLeu: 6.166 ± 2.52
0.0GluMet: 0.0 ± 0.0
4.111GluAsn: 4.111 ± 2.706
2.055GluPro: 2.055 ± 1.355
0.0GluGln: 0.0 ± 0.0
1.028GluArg: 1.028 ± 1.131
4.111GluSer: 4.111 ± 2.394
0.0GluThr: 0.0 ± 0.0
1.028GluVal: 1.028 ± 0.774
1.028GluTrp: 1.028 ± 0.774
1.028GluTyr: 1.028 ± 0.774
0.0GluXaa: 0.0 ± 0.0
Phe
1.028PheAla: 1.028 ± 1.144
3.083PheCys: 3.083 ± 1.281
4.111PheAsp: 4.111 ± 2.552
1.028PheGlu: 1.028 ± 0.774
2.055PhePhe: 2.055 ± 0.831
1.028PheGly: 1.028 ± 0.969
1.028PheHis: 1.028 ± 0.774
1.028PheIle: 1.028 ± 1.131
2.055PheLys: 2.055 ± 1.22
5.139PheLeu: 5.139 ± 2.368
1.028PheMet: 1.028 ± 0.774
4.111PheAsn: 4.111 ± 3.169
1.028PhePro: 1.028 ± 1.144
7.194PheGln: 7.194 ± 1.995
4.111PheArg: 4.111 ± 2.021
1.028PheSer: 1.028 ± 1.216
1.028PheThr: 1.028 ± 0.774
1.028PheVal: 1.028 ± 1.131
1.028PheTrp: 1.028 ± 0.969
2.055PheTyr: 2.055 ± 1.355
0.0PheXaa: 0.0 ± 0.0
Gly
3.083GlyAla: 3.083 ± 1.51
4.111GlyCys: 4.111 ± 1.56
3.083GlyAsp: 3.083 ± 1.51
3.083GlyGlu: 3.083 ± 1.562
1.028GlyPhe: 1.028 ± 1.144
5.139GlyGly: 5.139 ± 2.402
1.028GlyHis: 1.028 ± 0.774
2.055GlyIle: 2.055 ± 1.22
6.166GlyLys: 6.166 ± 1.553
1.028GlyLeu: 1.028 ± 0.969
0.0GlyMet: 0.0 ± 0.0
2.055GlyAsn: 2.055 ± 1.5
4.111GlyPro: 4.111 ± 1.663
2.055GlyGln: 2.055 ± 0.831
2.055GlyArg: 2.055 ± 1.22
2.055GlySer: 2.055 ± 0.831
3.083GlyThr: 3.083 ± 1.482
0.0GlyVal: 0.0 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.055HisAla: 2.055 ± 0.831
1.028HisCys: 1.028 ± 1.144
1.028HisAsp: 1.028 ± 1.131
2.055HisGlu: 2.055 ± 1.22
2.055HisPhe: 2.055 ± 1.549
0.0HisGly: 0.0 ± 0.0
2.055HisHis: 2.055 ± 1.355
4.111HisIle: 4.111 ± 2.942
2.055HisLys: 2.055 ± 1.22
2.055HisLeu: 2.055 ± 1.549
0.0HisMet: 0.0 ± 0.0
3.083HisAsn: 3.083 ± 1.702
1.028HisPro: 1.028 ± 0.774
2.055HisGln: 2.055 ± 1.189
4.111HisArg: 4.111 ± 3.388
1.028HisSer: 1.028 ± 0.774
3.083HisThr: 3.083 ± 2.908
3.083HisVal: 3.083 ± 2.109
0.0HisTrp: 0.0 ± 0.0
1.028HisTyr: 1.028 ± 0.774
0.0HisXaa: 0.0 ± 0.0
Ile
1.028IleAla: 1.028 ± 1.216
1.028IleCys: 1.028 ± 1.216
4.111IleAsp: 4.111 ± 2.251
4.111IleGlu: 4.111 ± 2.44
3.083IlePhe: 3.083 ± 2.323
2.055IleGly: 2.055 ± 2.287
1.028IleHis: 1.028 ± 1.131
5.139IleIle: 5.139 ± 1.35
7.194IleLys: 7.194 ± 1.995
1.028IleLeu: 1.028 ± 1.131
0.0IleMet: 0.0 ± 0.0
4.111IleAsn: 4.111 ± 0.918
1.028IlePro: 1.028 ± 0.774
5.139IleGln: 5.139 ± 1.153
4.111IleArg: 4.111 ± 2.021
5.139IleSer: 5.139 ± 2.302
1.028IleThr: 1.028 ± 1.131
4.111IleVal: 4.111 ± 1.393
2.055IleTrp: 2.055 ± 1.738
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.139LysAla: 5.139 ± 2.135
2.055LysCys: 2.055 ± 1.22
3.083LysAsp: 3.083 ± 2.323
5.139LysGlu: 5.139 ± 2.672
1.028LysPhe: 1.028 ± 1.131
1.028LysGly: 1.028 ± 0.774
1.028LysHis: 1.028 ± 0.774
5.139LysIle: 5.139 ± 1.598
3.083LysLys: 3.083 ± 2.313
1.028LysLeu: 1.028 ± 0.774
0.0LysMet: 0.0 ± 0.0
3.083LysAsn: 3.083 ± 2.323
2.055LysPro: 2.055 ± 0.831
0.0LysGln: 0.0 ± 0.0
7.194LysArg: 7.194 ± 4.288
5.139LysSer: 5.139 ± 1.35
1.028LysThr: 1.028 ± 0.774
5.139LysVal: 5.139 ± 1.35
0.0LysTrp: 0.0 ± 0.0
5.139LysTyr: 5.139 ± 1.759
0.0LysXaa: 0.0 ± 0.0
Leu
1.028LeuAla: 1.028 ± 0.774
2.055LeuCys: 2.055 ± 1.549
6.166LeuAsp: 6.166 ± 2.062
4.111LeuGlu: 4.111 ± 3.769
2.055LeuPhe: 2.055 ± 1.355
4.111LeuGly: 4.111 ± 0.918
3.083LeuHis: 3.083 ± 1.51
3.083LeuIle: 3.083 ± 1.562
5.139LeuLys: 5.139 ± 1.759
2.055LeuLeu: 2.055 ± 1.939
2.055LeuMet: 2.055 ± 1.699
6.166LeuAsn: 6.166 ± 1.822
2.055LeuPro: 2.055 ± 1.093
1.028LeuGln: 1.028 ± 0.774
7.194LeuArg: 7.194 ± 3.971
5.139LeuSer: 5.139 ± 1.153
7.194LeuThr: 7.194 ± 1.866
2.055LeuVal: 2.055 ± 0.831
0.0LeuTrp: 0.0 ± 0.0
5.139LeuTyr: 5.139 ± 1.836
0.0LeuXaa: 0.0 ± 0.0
Met
2.055MetAla: 2.055 ± 0.831
0.0MetCys: 0.0 ± 0.0
3.083MetAsp: 3.083 ± 0.88
0.0MetGlu: 0.0 ± 0.0
1.028MetPhe: 1.028 ± 0.969
2.055MetGly: 2.055 ± 1.136
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.028MetAsn: 1.028 ± 0.969
2.055MetPro: 2.055 ± 1.762
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.028MetSer: 1.028 ± 0.969
1.028MetThr: 1.028 ± 1.216
0.0MetVal: 0.0 ± 0.0
1.028MetTrp: 1.028 ± 0.774
3.083MetTyr: 3.083 ± 2.908
0.0MetXaa: 0.0 ± 0.0
Asn
4.111AsnAla: 4.111 ± 1.947
0.0AsnCys: 0.0 ± 0.0
3.083AsnAsp: 3.083 ± 0.88
1.028AsnGlu: 1.028 ± 0.969
3.083AsnPhe: 3.083 ± 2.109
1.028AsnGly: 1.028 ± 1.144
7.194AsnHis: 7.194 ± 4.109
2.055AsnIle: 2.055 ± 1.549
1.028AsnLys: 1.028 ± 0.969
4.111AsnLeu: 4.111 ± 2.48
2.055AsnMet: 2.055 ± 1.808
0.0AsnAsn: 0.0 ± 0.0
4.111AsnPro: 4.111 ± 0.918
2.055AsnGln: 2.055 ± 1.549
2.055AsnArg: 2.055 ± 0.831
4.111AsnSer: 4.111 ± 2.303
3.083AsnThr: 3.083 ± 1.102
5.139AsnVal: 5.139 ± 2.017
0.0AsnTrp: 0.0 ± 0.0
2.055AsnTyr: 2.055 ± 1.549
0.0AsnXaa: 0.0 ± 0.0
Pro
1.028ProAla: 1.028 ± 0.969
1.028ProCys: 1.028 ± 0.969
2.055ProAsp: 2.055 ± 0.831
3.083ProGlu: 3.083 ± 2.099
2.055ProPhe: 2.055 ± 1.22
1.028ProGly: 1.028 ± 0.774
4.111ProHis: 4.111 ± 2.136
3.083ProIle: 3.083 ± 0.935
3.083ProLys: 3.083 ± 2.323
3.083ProLeu: 3.083 ± 1.403
0.0ProMet: 0.0 ± 0.0
2.055ProAsn: 2.055 ± 1.549
5.139ProPro: 5.139 ± 2.306
5.139ProGln: 5.139 ± 1.394
4.111ProArg: 4.111 ± 2.388
8.222ProSer: 8.222 ± 3.684
6.166ProThr: 6.166 ± 3.035
3.083ProVal: 3.083 ± 2.06
1.028ProTrp: 1.028 ± 0.774
2.055ProTyr: 2.055 ± 1.939
0.0ProXaa: 0.0 ± 0.0
Gln
2.055GlnAla: 2.055 ± 1.22
1.028GlnCys: 1.028 ± 0.774
2.055GlnAsp: 2.055 ± 1.355
1.028GlnGlu: 1.028 ± 0.969
1.028GlnPhe: 1.028 ± 0.774
2.055GlnGly: 2.055 ± 0.831
2.055GlnHis: 2.055 ± 1.762
3.083GlnIle: 3.083 ± 1.702
2.055GlnLys: 2.055 ± 1.549
3.083GlnLeu: 3.083 ± 1.484
0.0GlnMet: 0.0 ± 0.0
2.055GlnAsn: 2.055 ± 1.22
5.139GlnPro: 5.139 ± 2.306
0.0GlnGln: 0.0 ± 0.0
4.111GlnArg: 4.111 ± 1.947
3.083GlnSer: 3.083 ± 1.281
2.055GlnThr: 2.055 ± 1.738
9.25GlnVal: 9.25 ± 1.985
0.0GlnTrp: 0.0 ± 0.0
1.028GlnTyr: 1.028 ± 0.774
0.0GlnXaa: 0.0 ± 0.0
Arg
2.055ArgAla: 2.055 ± 1.738
1.028ArgCys: 1.028 ± 0.969
4.111ArgAsp: 4.111 ± 2.552
4.111ArgGlu: 4.111 ± 1.582
7.194ArgPhe: 7.194 ± 2.118
4.111ArgGly: 4.111 ± 1.56
1.028ArgHis: 1.028 ± 1.144
2.055ArgIle: 2.055 ± 2.287
3.083ArgLys: 3.083 ± 1.482
4.111ArgLeu: 4.111 ± 2.388
3.083ArgMet: 3.083 ± 3.019
0.0ArgAsn: 0.0 ± 0.0
8.222ArgPro: 8.222 ± 1.704
0.0ArgGln: 0.0 ± 0.0
8.222ArgArg: 8.222 ± 5.254
9.25ArgSer: 9.25 ± 1.752
6.166ArgThr: 6.166 ± 1.96
3.083ArgVal: 3.083 ± 1.727
1.028ArgTrp: 1.028 ± 0.774
1.028ArgTyr: 1.028 ± 0.969
0.0ArgXaa: 0.0 ± 0.0
Ser
9.25SerAla: 9.25 ± 3.956
1.028SerCys: 1.028 ± 0.774
4.111SerAsp: 4.111 ± 1.309
0.0SerGlu: 0.0 ± 0.0
5.139SerPhe: 5.139 ± 2.198
2.055SerGly: 2.055 ± 1.5
1.028SerHis: 1.028 ± 0.774
7.194SerIle: 7.194 ± 3.17
2.055SerLys: 2.055 ± 1.939
7.194SerLeu: 7.194 ± 2.417
0.0SerMet: 0.0 ± 0.0
6.166SerAsn: 6.166 ± 0.771
10.277SerPro: 10.277 ± 2.48
2.055SerGln: 2.055 ± 1.093
7.194SerArg: 7.194 ± 5.24
13.361SerSer: 13.361 ± 5.346
6.166SerThr: 6.166 ± 1.306
5.139SerVal: 5.139 ± 2.957
1.028SerTrp: 1.028 ± 0.969
3.083SerTyr: 3.083 ± 1.281
0.0SerXaa: 0.0 ± 0.0
Thr
2.055ThrAla: 2.055 ± 1.189
1.028ThrCys: 1.028 ± 0.969
1.028ThrAsp: 1.028 ± 1.216
1.028ThrGlu: 1.028 ± 0.969
1.028ThrPhe: 1.028 ± 1.216
7.194ThrGly: 7.194 ± 3.099
4.111ThrHis: 4.111 ± 1.56
2.055ThrIle: 2.055 ± 1.22
2.055ThrLys: 2.055 ± 1.549
2.055ThrLeu: 2.055 ± 1.22
1.028ThrMet: 1.028 ± 0.774
5.139ThrAsn: 5.139 ± 2.233
3.083ThrPro: 3.083 ± 1.281
5.139ThrGln: 5.139 ± 1.774
2.055ThrArg: 2.055 ± 0.831
5.139ThrSer: 5.139 ± 3.619
1.028ThrThr: 1.028 ± 1.131
3.083ThrVal: 3.083 ± 2.214
0.0ThrTrp: 0.0 ± 0.0
3.083ThrTyr: 3.083 ± 1.632
0.0ThrXaa: 0.0 ± 0.0
Val
2.055ValAla: 2.055 ± 1.189
1.028ValCys: 1.028 ± 0.774
3.083ValAsp: 3.083 ± 1.702
1.028ValGlu: 1.028 ± 0.774
4.111ValPhe: 4.111 ± 2.262
0.0ValGly: 0.0 ± 0.0
2.055ValHis: 2.055 ± 1.189
5.139ValIle: 5.139 ± 2.112
3.083ValLys: 3.083 ± 1.632
6.166ValLeu: 6.166 ± 3.516
2.055ValMet: 2.055 ± 0.831
0.0ValAsn: 0.0 ± 0.0
5.139ValPro: 5.139 ± 1.762
5.139ValGln: 5.139 ± 3.015
4.111ValArg: 4.111 ± 2.706
3.083ValSer: 3.083 ± 1.281
4.111ValThr: 4.111 ± 3.878
3.083ValVal: 3.083 ± 1.727
2.055ValTrp: 2.055 ± 1.189
4.111ValTyr: 4.111 ± 1.663
0.0ValXaa: 0.0 ± 0.0
Trp
3.083TrpAla: 3.083 ± 2.323
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.028TrpGlu: 1.028 ± 1.131
0.0TrpPhe: 0.0 ± 0.0
1.028TrpGly: 1.028 ± 0.774
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.028TrpLeu: 1.028 ± 0.969
1.028TrpMet: 1.028 ± 0.969
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.028TrpGln: 1.028 ± 0.774
1.028TrpArg: 1.028 ± 0.774
2.055TrpSer: 2.055 ± 1.762
2.055TrpThr: 2.055 ± 1.189
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.028TrpTyr: 1.028 ± 0.774
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.028TyrAla: 1.028 ± 0.969
0.0TyrCys: 0.0 ± 0.0
1.028TyrAsp: 1.028 ± 0.969
1.028TyrGlu: 1.028 ± 0.969
3.083TyrPhe: 3.083 ± 0.88
2.055TyrGly: 2.055 ± 0.831
1.028TyrHis: 1.028 ± 0.774
3.083TyrIle: 3.083 ± 2.323
2.055TyrLys: 2.055 ± 1.549
6.166TyrLeu: 6.166 ± 2.496
2.055TyrMet: 2.055 ± 1.095
2.055TyrAsn: 2.055 ± 0.831
1.028TyrPro: 1.028 ± 0.774
1.028TyrGln: 1.028 ± 0.969
4.111TyrArg: 4.111 ± 3.878
2.055TyrSer: 2.055 ± 1.549
1.028TyrThr: 1.028 ± 0.969
2.055TyrVal: 2.055 ± 0.831
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (974 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski