Amino acid dipepetide frequency for Maize striate mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.009AlaAla: 3.009 ± 2.468
2.006AlaCys: 2.006 ± 0.78
1.003AlaAsp: 1.003 ± 0.823
3.009AlaGlu: 3.009 ± 0.58
5.015AlaPhe: 5.015 ± 1.582
6.018AlaGly: 6.018 ± 2.087
1.003AlaHis: 1.003 ± 0.939
4.012AlaIle: 4.012 ± 1.921
7.021AlaLys: 7.021 ± 1.313
4.012AlaLeu: 4.012 ± 3.67
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
6.018AlaPro: 6.018 ± 0.706
4.012AlaGln: 4.012 ± 1.56
5.015AlaArg: 5.015 ± 2.006
5.015AlaSer: 5.015 ± 1.863
6.018AlaThr: 6.018 ± 1.366
4.012AlaVal: 4.012 ± 0.767
1.003AlaTrp: 1.003 ± 0.733
3.009AlaTyr: 3.009 ± 0.58
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.006CysAsp: 2.006 ± 0.78
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.006CysGly: 2.006 ± 0.897
2.006CysHis: 2.006 ± 0.78
0.0CysIle: 0.0 ± 0.0
2.006CysLys: 2.006 ± 1.878
3.009CysLeu: 3.009 ± 0.58
0.0CysMet: 0.0 ± 0.0
1.003CysAsn: 1.003 ± 0.939
3.009CysPro: 3.009 ± 1.27
2.006CysGln: 2.006 ± 0.78
3.009CysArg: 3.009 ± 0.58
2.006CysSer: 2.006 ± 0.78
1.003CysThr: 1.003 ± 0.823
3.009CysVal: 3.009 ± 2.491
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.015AspAla: 5.015 ± 1.004
3.009AspCys: 3.009 ± 1.2
3.009AspAsp: 3.009 ± 1.27
2.006AspGlu: 2.006 ± 0.897
1.003AspPhe: 1.003 ± 1.262
3.009AspGly: 3.009 ± 0.58
4.012AspHis: 4.012 ± 1.107
2.006AspIle: 2.006 ± 0.897
0.0AspLys: 0.0 ± 0.0
5.015AspLeu: 5.015 ± 2.148
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
5.015AspPro: 5.015 ± 2.148
1.003AspGln: 1.003 ± 1.262
1.003AspArg: 1.003 ± 1.262
2.006AspSer: 2.006 ± 0.78
0.0AspThr: 0.0 ± 0.0
2.006AspVal: 2.006 ± 1.01
3.009AspTrp: 3.009 ± 1.342
8.024AspTyr: 8.024 ± 1.704
0.0AspXaa: 0.0 ± 0.0
Glu
3.009GluAla: 3.009 ± 1.427
0.0GluCys: 0.0 ± 0.0
3.009GluAsp: 3.009 ± 1.27
2.006GluGlu: 2.006 ± 0.78
4.012GluPhe: 4.012 ± 1.567
1.003GluGly: 1.003 ± 0.823
1.003GluHis: 1.003 ± 0.939
2.006GluIle: 2.006 ± 0.78
1.003GluLys: 1.003 ± 1.262
1.003GluLeu: 1.003 ± 0.939
2.006GluMet: 2.006 ± 1.285
5.015GluAsn: 5.015 ± 1.976
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
2.006GluArg: 2.006 ± 0.78
3.009GluSer: 3.009 ± 1.684
2.006GluThr: 2.006 ± 1.376
5.015GluVal: 5.015 ± 2.006
3.009GluTrp: 3.009 ± 0.58
2.006GluTyr: 2.006 ± 0.78
0.0GluXaa: 0.0 ± 0.0
Phe
2.006PheAla: 2.006 ± 0.897
1.003PheCys: 1.003 ± 0.733
4.012PheAsp: 4.012 ± 1.56
5.015PheGlu: 5.015 ± 1.582
1.003PhePhe: 1.003 ± 0.733
3.009PheGly: 3.009 ± 2.468
2.006PheHis: 2.006 ± 0.78
0.0PheIle: 0.0 ± 0.0
5.015PheLys: 5.015 ± 1.266
8.024PheLeu: 8.024 ± 2.698
0.0PheMet: 0.0 ± 0.0
1.003PheAsn: 1.003 ± 0.733
4.012PhePro: 4.012 ± 1.56
1.003PheGln: 1.003 ± 0.733
4.012PheArg: 4.012 ± 1.56
3.009PheSer: 3.009 ± 2.494
0.0PheThr: 0.0 ± 0.0
3.009PheVal: 3.009 ± 1.99
0.0PheTrp: 0.0 ± 0.0
1.003PheTyr: 1.003 ± 1.262
0.0PheXaa: 0.0 ± 0.0
Gly
10.03GlyAla: 10.03 ± 3.024
0.0GlyCys: 0.0 ± 0.0
4.012GlyAsp: 4.012 ± 1.774
1.003GlyGlu: 1.003 ± 0.733
1.003GlyPhe: 1.003 ± 1.262
7.021GlyGly: 7.021 ± 1.729
1.003GlyHis: 1.003 ± 0.823
3.009GlyIle: 3.009 ± 1.211
4.012GlyLys: 4.012 ± 0.852
3.009GlyLeu: 3.009 ± 0.58
1.003GlyMet: 1.003 ± 0.939
4.012GlyAsn: 4.012 ± 2.791
6.018GlyPro: 6.018 ± 3.55
3.009GlyGln: 3.009 ± 0.58
5.015GlyArg: 5.015 ± 1.976
7.021GlySer: 7.021 ± 2.936
4.012GlyThr: 4.012 ± 1.352
0.0GlyVal: 0.0 ± 0.0
1.003GlyTrp: 1.003 ± 0.939
1.003GlyTyr: 1.003 ± 0.939
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.003HisCys: 1.003 ± 0.939
1.003HisAsp: 1.003 ± 0.733
2.006HisGlu: 2.006 ± 0.78
0.0HisPhe: 0.0 ± 0.0
1.003HisGly: 1.003 ± 0.823
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.006HisLys: 2.006 ± 0.78
2.006HisLeu: 2.006 ± 0.78
2.006HisMet: 2.006 ± 0.897
1.003HisAsn: 1.003 ± 0.733
2.006HisPro: 2.006 ± 0.78
1.003HisGln: 1.003 ± 0.733
1.003HisArg: 1.003 ± 0.939
2.006HisSer: 2.006 ± 0.78
5.015HisThr: 5.015 ± 1.863
5.015HisVal: 5.015 ± 1.004
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.003IleCys: 1.003 ± 0.733
4.012IleAsp: 4.012 ± 1.921
2.006IleGlu: 2.006 ± 0.78
1.003IlePhe: 1.003 ± 0.939
4.012IleGly: 4.012 ± 0.767
0.0IleHis: 0.0 ± 0.0
1.003IleIle: 1.003 ± 0.733
2.006IleLys: 2.006 ± 0.897
1.003IleLeu: 1.003 ± 0.733
4.012IleMet: 4.012 ± 1.56
2.006IleAsn: 2.006 ± 0.78
7.021IlePro: 7.021 ± 1.948
4.012IleGln: 4.012 ± 1.56
2.006IleArg: 2.006 ± 0.78
2.006IleSer: 2.006 ± 0.78
1.003IleThr: 1.003 ± 1.262
2.006IleVal: 2.006 ± 1.334
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.006LysAla: 2.006 ± 0.897
2.006LysCys: 2.006 ± 0.78
3.009LysAsp: 3.009 ± 0.58
1.003LysGlu: 1.003 ± 0.823
1.003LysPhe: 1.003 ± 0.733
7.021LysGly: 7.021 ± 0.506
0.0LysHis: 0.0 ± 0.0
1.003LysIle: 1.003 ± 0.733
5.015LysLys: 5.015 ± 1.266
5.015LysLeu: 5.015 ± 1.004
3.009LysMet: 3.009 ± 0.58
5.015LysAsn: 5.015 ± 1.004
1.003LysPro: 1.003 ± 0.939
3.009LysGln: 3.009 ± 0.58
6.018LysArg: 6.018 ± 2.044
3.009LysSer: 3.009 ± 1.99
2.006LysThr: 2.006 ± 0.897
1.003LysVal: 1.003 ± 0.939
0.0LysTrp: 0.0 ± 0.0
2.006LysTyr: 2.006 ± 0.897
0.0LysXaa: 0.0 ± 0.0
Leu
6.018LeuAla: 6.018 ± 0.706
4.012LeuCys: 4.012 ± 1.107
2.006LeuAsp: 2.006 ± 1.01
1.003LeuGlu: 1.003 ± 0.733
3.009LeuPhe: 3.009 ± 1.2
1.003LeuGly: 1.003 ± 0.733
2.006LeuHis: 2.006 ± 0.78
2.006LeuIle: 2.006 ± 0.78
0.0LeuLys: 0.0 ± 0.0
3.009LeuLeu: 3.009 ± 3.785
2.006LeuMet: 2.006 ± 0.897
1.003LeuAsn: 1.003 ± 0.939
4.012LeuPro: 4.012 ± 2.791
2.006LeuGln: 2.006 ± 1.376
3.009LeuArg: 3.009 ± 0.58
5.015LeuSer: 5.015 ± 3.557
5.015LeuThr: 5.015 ± 2.148
6.018LeuVal: 6.018 ± 1.927
2.006LeuTrp: 2.006 ± 0.78
7.021LeuTyr: 7.021 ± 1.003
0.0LeuXaa: 0.0 ± 0.0
Met
2.006MetAla: 2.006 ± 1.01
2.006MetCys: 2.006 ± 0.78
1.003MetAsp: 1.003 ± 1.262
3.009MetGlu: 3.009 ± 1.99
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.006MetPro: 2.006 ± 0.78
0.0MetGln: 0.0 ± 0.0
1.003MetArg: 1.003 ± 0.939
7.021MetSer: 7.021 ± 1.702
4.012MetThr: 4.012 ± 1.794
4.012MetVal: 4.012 ± 1.352
0.0MetTrp: 0.0 ± 0.0
1.003MetTyr: 1.003 ± 0.939
0.0MetXaa: 0.0 ± 0.0
Asn
2.006AsnAla: 2.006 ± 0.78
3.009AsnCys: 3.009 ± 1.684
0.0AsnAsp: 0.0 ± 0.0
5.015AsnGlu: 5.015 ± 1.004
0.0AsnPhe: 0.0 ± 0.0
2.006AsnGly: 2.006 ± 1.878
2.006AsnHis: 2.006 ± 0.78
6.018AsnIle: 6.018 ± 2.34
0.0AsnLys: 0.0 ± 0.0
2.006AsnLeu: 2.006 ± 0.78
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.003AsnPro: 1.003 ± 0.733
2.006AsnGln: 2.006 ± 1.878
2.006AsnArg: 2.006 ± 1.878
1.003AsnSer: 1.003 ± 0.939
5.015AsnThr: 5.015 ± 1.032
4.012AsnVal: 4.012 ± 1.56
1.003AsnTrp: 1.003 ± 0.733
2.006AsnTyr: 2.006 ± 1.465
0.0AsnXaa: 0.0 ± 0.0
Pro
1.003ProAla: 1.003 ± 0.733
1.003ProCys: 1.003 ± 0.939
3.009ProAsp: 3.009 ± 0.58
4.012ProGlu: 4.012 ± 1.567
5.015ProPhe: 5.015 ± 2.4
6.018ProGly: 6.018 ± 2.399
1.003ProHis: 1.003 ± 0.733
2.006ProIle: 2.006 ± 0.78
4.012ProLys: 4.012 ± 1.56
2.006ProLeu: 2.006 ± 0.78
1.003ProMet: 1.003 ± 0.939
3.009ProAsn: 3.009 ± 1.27
4.012ProPro: 4.012 ± 3.67
1.003ProGln: 1.003 ± 1.262
5.015ProArg: 5.015 ± 1.004
7.021ProSer: 7.021 ± 0.506
6.018ProThr: 6.018 ± 1.16
2.006ProVal: 2.006 ± 2.523
2.006ProTrp: 2.006 ± 0.78
3.009ProTyr: 3.009 ± 0.58
0.0ProXaa: 0.0 ± 0.0
Gln
3.009GlnAla: 3.009 ± 1.2
0.0GlnCys: 0.0 ± 0.0
2.006GlnAsp: 2.006 ± 0.78
3.009GlnGlu: 3.009 ± 1.427
3.009GlnPhe: 3.009 ± 0.58
3.009GlnGly: 3.009 ± 1.684
3.009GlnHis: 3.009 ± 1.27
3.009GlnIle: 3.009 ± 1.27
0.0GlnLys: 0.0 ± 0.0
2.006GlnLeu: 2.006 ± 1.376
1.003GlnMet: 1.003 ± 0.821
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
1.003GlnArg: 1.003 ± 0.939
0.0GlnSer: 0.0 ± 0.0
4.012GlnThr: 4.012 ± 0.767
3.009GlnVal: 3.009 ± 1.684
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.021ArgAla: 7.021 ± 3.209
2.006ArgCys: 2.006 ± 0.78
8.024ArgAsp: 8.024 ± 1.275
0.0ArgGlu: 0.0 ± 0.0
3.009ArgPhe: 3.009 ± 0.58
5.015ArgGly: 5.015 ± 1.004
1.003ArgHis: 1.003 ± 0.939
2.006ArgIle: 2.006 ± 0.78
5.015ArgLys: 5.015 ± 1.266
1.003ArgLeu: 1.003 ± 0.939
3.009ArgMet: 3.009 ± 1.768
3.009ArgAsn: 3.009 ± 1.427
5.015ArgPro: 5.015 ± 1.004
1.003ArgGln: 1.003 ± 0.823
4.012ArgArg: 4.012 ± 1.709
5.015ArgSer: 5.015 ± 1.479
7.021ArgThr: 7.021 ± 2.809
1.003ArgVal: 1.003 ± 0.939
2.006ArgTrp: 2.006 ± 1.01
1.003ArgTyr: 1.003 ± 1.262
0.0ArgXaa: 0.0 ± 0.0
Ser
10.03SerAla: 10.03 ± 2.938
0.0SerCys: 0.0 ± 0.0
4.012SerAsp: 4.012 ± 0.767
3.009SerGlu: 3.009 ± 1.2
4.012SerPhe: 4.012 ± 0.852
3.009SerGly: 3.009 ± 1.427
4.012SerHis: 4.012 ± 1.56
4.012SerIle: 4.012 ± 0.767
6.018SerLys: 6.018 ± 1.16
6.018SerLeu: 6.018 ± 0.962
3.009SerMet: 3.009 ± 1.463
6.018SerAsn: 6.018 ± 2.212
2.006SerPro: 2.006 ± 1.363
5.015SerGln: 5.015 ± 2.53
7.021SerArg: 7.021 ± 1.857
6.018SerSer: 6.018 ± 2.212
3.009SerThr: 3.009 ± 1.427
2.006SerVal: 2.006 ± 1.878
0.0SerTrp: 0.0 ± 0.0
2.006SerTyr: 2.006 ± 1.01
0.0SerXaa: 0.0 ± 0.0
Thr
1.003ThrAla: 1.003 ± 0.939
3.009ThrCys: 3.009 ± 0.58
0.0ThrAsp: 0.0 ± 0.0
3.009ThrGlu: 3.009 ± 1.211
3.009ThrPhe: 3.009 ± 0.58
8.024ThrGly: 8.024 ± 2.704
1.003ThrHis: 1.003 ± 0.939
4.012ThrIle: 4.012 ± 0.767
2.006ThrLys: 2.006 ± 0.78
1.003ThrLeu: 1.003 ± 1.262
1.003ThrMet: 1.003 ± 0.939
3.009ThrAsn: 3.009 ± 0.58
5.015ThrPro: 5.015 ± 2.4
0.0ThrGln: 0.0 ± 0.0
6.018ThrArg: 6.018 ± 1.627
10.03ThrSer: 10.03 ± 3.024
10.03ThrThr: 10.03 ± 2.082
3.009ThrVal: 3.009 ± 0.58
4.012ThrTrp: 4.012 ± 0.767
8.024ThrTyr: 8.024 ± 1.442
0.0ThrXaa: 0.0 ± 0.0
Val
8.024ValAla: 8.024 ± 3.451
1.003ValCys: 1.003 ± 1.262
2.006ValAsp: 2.006 ± 0.897
2.006ValGlu: 2.006 ± 1.376
6.018ValPhe: 6.018 ± 2.399
1.003ValGly: 1.003 ± 0.733
2.006ValHis: 2.006 ± 0.78
1.003ValIle: 1.003 ± 0.733
3.009ValLys: 3.009 ± 2.818
7.021ValLeu: 7.021 ± 2.54
2.006ValMet: 2.006 ± 1.237
3.009ValAsn: 3.009 ± 1.342
2.006ValPro: 2.006 ± 1.363
1.003ValGln: 1.003 ± 0.939
5.015ValArg: 5.015 ± 1.582
4.012ValSer: 4.012 ± 1.107
4.012ValThr: 4.012 ± 1.352
9.027ValVal: 9.027 ± 2.467
0.0ValTrp: 0.0 ± 0.0
3.009ValTyr: 3.009 ± 1.684
0.0ValXaa: 0.0 ± 0.0
Trp
3.009TrpAla: 3.009 ± 1.27
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.003TrpPhe: 1.003 ± 0.733
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
3.009TrpLys: 3.009 ± 1.684
3.009TrpLeu: 3.009 ± 1.27
1.003TrpMet: 1.003 ± 0.823
2.006TrpAsn: 2.006 ± 0.78
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.003TrpArg: 1.003 ± 1.262
2.006TrpSer: 2.006 ± 0.897
2.006TrpThr: 2.006 ± 1.01
2.006TrpVal: 2.006 ± 1.376
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.006TyrAla: 2.006 ± 0.78
0.0TyrCys: 0.0 ± 0.0
3.009TyrAsp: 3.009 ± 0.58
0.0TyrGlu: 0.0 ± 0.0
6.018TyrPhe: 6.018 ± 1.366
3.009TyrGly: 3.009 ± 1.684
1.003TyrHis: 1.003 ± 0.733
3.009TyrIle: 3.009 ± 1.27
2.006TyrLys: 2.006 ± 1.376
2.006TyrLeu: 2.006 ± 0.78
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
4.012TyrPro: 4.012 ± 1.352
0.0TyrGln: 0.0 ± 0.0
2.006TyrArg: 2.006 ± 1.376
5.015TyrSer: 5.015 ± 2.255
5.015TyrThr: 5.015 ± 1.976
5.015TyrVal: 5.015 ± 1.266
1.003TyrTrp: 1.003 ± 1.262
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (998 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski