Amino acid dipepetide frequency for Tortoise microvirus 36

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.896AlaAla: 4.896 ± 1.826
1.836AlaCys: 1.836 ± 0.937
5.508AlaAsp: 5.508 ± 1.522
4.896AlaGlu: 4.896 ± 1.462
3.672AlaPhe: 3.672 ± 0.84
4.896AlaGly: 4.896 ± 1.567
0.612AlaHis: 0.612 ± 0.666
4.284AlaIle: 4.284 ± 1.147
4.896AlaLys: 4.896 ± 1.812
8.568AlaLeu: 8.568 ± 2.723
0.612AlaMet: 0.612 ± 0.523
2.448AlaAsn: 2.448 ± 1.519
3.672AlaPro: 3.672 ± 1.213
4.284AlaGln: 4.284 ± 2.417
3.06AlaArg: 3.06 ± 0.575
6.732AlaSer: 6.732 ± 1.705
5.508AlaThr: 5.508 ± 1.73
7.344AlaVal: 7.344 ± 1.694
0.612AlaTrp: 0.612 ± 0.523
2.448AlaTyr: 2.448 ± 0.863
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.224CysCys: 1.224 ± 1.332
1.836CysAsp: 1.836 ± 1.038
0.0CysGlu: 0.0 ± 0.0
2.448CysPhe: 2.448 ± 1.273
0.612CysGly: 0.612 ± 0.666
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.448CysLys: 2.448 ± 1.723
1.224CysLeu: 1.224 ± 1.002
1.836CysMet: 1.836 ± 1.75
0.612CysAsn: 0.612 ± 0.722
0.0CysPro: 0.0 ± 0.0
0.612CysGln: 0.612 ± 0.439
1.224CysArg: 1.224 ± 0.566
0.0CysSer: 0.0 ± 0.0
1.224CysThr: 1.224 ± 0.537
1.224CysVal: 1.224 ± 1.21
0.0CysTrp: 0.0 ± 0.0
1.224CysTyr: 1.224 ± 1.01
0.0CysXaa: 0.0 ± 0.0
Asp
3.672AspAla: 3.672 ± 1.36
2.448AspCys: 2.448 ± 1.131
6.12AspAsp: 6.12 ± 1.99
3.06AspGlu: 3.06 ± 0.752
3.06AspPhe: 3.06 ± 1.187
1.224AspGly: 1.224 ± 0.75
0.612AspHis: 0.612 ± 0.757
5.508AspIle: 5.508 ± 2.362
3.06AspLys: 3.06 ± 1.207
3.672AspLeu: 3.672 ± 1.47
0.612AspMet: 0.612 ± 0.439
5.508AspAsn: 5.508 ± 1.76
1.224AspPro: 1.224 ± 0.773
0.0AspGln: 0.0 ± 0.0
1.836AspArg: 1.836 ± 0.762
4.896AspSer: 4.896 ± 0.895
7.344AspThr: 7.344 ± 2.157
6.732AspVal: 6.732 ± 2.672
0.612AspTrp: 0.612 ± 0.666
5.508AspTyr: 5.508 ± 1.927
0.0AspXaa: 0.0 ± 0.0
Glu
3.672GluAla: 3.672 ± 2.471
0.0GluCys: 0.0 ± 0.0
0.612GluAsp: 0.612 ± 0.757
1.836GluGlu: 1.836 ± 1.193
4.284GluPhe: 4.284 ± 2.016
0.612GluGly: 0.612 ± 0.523
0.612GluHis: 0.612 ± 0.439
3.672GluIle: 3.672 ± 0.729
1.836GluLys: 1.836 ± 1.01
6.12GluLeu: 6.12 ± 1.219
3.06GluMet: 3.06 ± 1.248
1.224GluAsn: 1.224 ± 0.723
0.612GluPro: 0.612 ± 0.757
1.836GluGln: 1.836 ± 1.57
3.06GluArg: 3.06 ± 1.127
4.284GluSer: 4.284 ± 1.99
4.284GluThr: 4.284 ± 1.459
1.836GluVal: 1.836 ± 0.955
0.0GluTrp: 0.0 ± 0.0
2.448GluTyr: 2.448 ± 1.389
0.0GluXaa: 0.0 ± 0.0
Phe
3.672PheAla: 3.672 ± 1.266
0.612PheCys: 0.612 ± 0.666
5.508PheAsp: 5.508 ± 2.447
1.836PheGlu: 1.836 ± 0.829
3.672PhePhe: 3.672 ± 1.552
2.448PheGly: 2.448 ± 0.889
1.224PheHis: 1.224 ± 1.21
4.284PheIle: 4.284 ± 2.263
3.06PheLys: 3.06 ± 0.575
4.284PheLeu: 4.284 ± 2.541
1.224PheMet: 1.224 ± 0.877
1.836PheAsn: 1.836 ± 0.966
3.06PhePro: 3.06 ± 1.045
1.224PheGln: 1.224 ± 0.566
1.224PheArg: 1.224 ± 0.566
1.224PheSer: 1.224 ± 1.047
4.896PheThr: 4.896 ± 1.745
3.672PheVal: 3.672 ± 1.839
0.612PheTrp: 0.612 ± 0.523
4.896PheTyr: 4.896 ± 1.029
0.0PheXaa: 0.0 ± 0.0
Gly
3.672GlyAla: 3.672 ± 0.646
0.612GlyCys: 0.612 ± 0.439
3.06GlyAsp: 3.06 ± 1.606
1.224GlyGlu: 1.224 ± 0.718
3.672GlyPhe: 3.672 ± 2.155
1.836GlyGly: 1.836 ± 0.829
1.836GlyHis: 1.836 ± 0.778
4.896GlyIle: 4.896 ± 1.692
3.06GlyLys: 3.06 ± 1.126
6.732GlyLeu: 6.732 ± 1.708
0.612GlyMet: 0.612 ± 0.439
2.448GlyAsn: 2.448 ± 1.341
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
1.836GlyArg: 1.836 ± 0.937
6.12GlySer: 6.12 ± 1.832
2.448GlyThr: 2.448 ± 1.108
3.06GlyVal: 3.06 ± 1.079
1.224GlyTrp: 1.224 ± 0.537
4.284GlyTyr: 4.284 ± 0.859
0.0GlyXaa: 0.0 ± 0.0
His
2.448HisAla: 2.448 ± 1.131
0.0HisCys: 0.0 ± 0.0
0.612HisAsp: 0.612 ± 0.722
0.0HisGlu: 0.0 ± 0.0
0.612HisPhe: 0.612 ± 0.829
0.612HisGly: 0.612 ± 0.439
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.612HisLys: 0.612 ± 0.757
1.836HisLeu: 1.836 ± 0.829
1.224HisMet: 1.224 ± 0.551
0.612HisAsn: 0.612 ± 0.757
0.612HisPro: 0.612 ± 0.721
0.0HisGln: 0.0 ± 0.0
1.224HisArg: 1.224 ± 0.877
3.06HisSer: 3.06 ± 0.706
0.612HisThr: 0.612 ± 0.439
0.0HisVal: 0.0 ± 0.0
0.612HisTrp: 0.612 ± 0.666
0.612HisTyr: 0.612 ± 0.666
0.0HisXaa: 0.0 ± 0.0
Ile
4.284IleAla: 4.284 ± 1.933
0.0IleCys: 0.0 ± 0.0
4.284IleAsp: 4.284 ± 2.827
1.224IleGlu: 1.224 ± 1.107
0.612IlePhe: 0.612 ± 0.722
2.448IleGly: 2.448 ± 1.025
0.612IleHis: 0.612 ± 0.439
1.224IleIle: 1.224 ± 0.877
0.612IleLys: 0.612 ± 0.439
4.896IleLeu: 4.896 ± 1.686
1.224IleMet: 1.224 ± 0.877
4.284IleAsn: 4.284 ± 1.146
5.508IlePro: 5.508 ± 2.028
1.836IleGln: 1.836 ± 1.227
4.896IleArg: 4.896 ± 1.621
6.732IleSer: 6.732 ± 1.302
3.06IleThr: 3.06 ± 0.752
0.612IleVal: 0.612 ± 0.666
1.224IleTrp: 1.224 ± 0.877
2.448IleTyr: 2.448 ± 1.014
0.0IleXaa: 0.0 ± 0.0
Lys
2.448LysAla: 2.448 ± 0.863
0.612LysCys: 0.612 ± 0.722
2.448LysAsp: 2.448 ± 0.795
4.284LysGlu: 4.284 ± 1.519
1.224LysPhe: 1.224 ± 0.995
1.836LysGly: 1.836 ± 0.464
0.0LysHis: 0.0 ± 0.0
1.224LysIle: 1.224 ± 0.723
0.612LysLys: 0.612 ± 0.757
3.06LysLeu: 3.06 ± 0.87
1.224LysMet: 1.224 ± 0.924
4.284LysAsn: 4.284 ± 2.355
0.612LysPro: 0.612 ± 0.721
1.836LysGln: 1.836 ± 1.066
3.672LysArg: 3.672 ± 2.618
3.672LysSer: 3.672 ± 2.091
3.06LysThr: 3.06 ± 1.327
1.224LysVal: 1.224 ± 0.566
1.836LysTrp: 1.836 ± 0.717
1.224LysTyr: 1.224 ± 1.332
0.0LysXaa: 0.0 ± 0.0
Leu
10.404LeuAla: 10.404 ± 1.869
1.224LeuCys: 1.224 ± 1.138
6.732LeuAsp: 6.732 ± 1.411
6.12LeuGlu: 6.12 ± 0.87
4.284LeuPhe: 4.284 ± 1.456
7.956LeuGly: 7.956 ± 1.553
1.836LeuHis: 1.836 ± 0.906
2.448LeuIle: 2.448 ± 1.074
4.284LeuLys: 4.284 ± 2.429
5.508LeuLeu: 5.508 ± 2.513
1.224LeuMet: 1.224 ± 1.11
4.284LeuAsn: 4.284 ± 2.264
8.568LeuPro: 8.568 ± 2.019
1.836LeuGln: 1.836 ± 1.038
4.284LeuArg: 4.284 ± 1.42
7.956LeuSer: 7.956 ± 1.612
4.896LeuThr: 4.896 ± 1.534
3.06LeuVal: 3.06 ± 0.966
1.224LeuTrp: 1.224 ± 0.877
3.672LeuTyr: 3.672 ± 1.668
0.0LeuXaa: 0.0 ± 0.0
Met
1.836MetAla: 1.836 ± 0.829
1.224MetCys: 1.224 ± 1.117
4.284MetAsp: 4.284 ± 0.768
0.612MetGlu: 0.612 ± 0.523
1.836MetPhe: 1.836 ± 1.519
1.836MetGly: 1.836 ± 1.155
0.0MetHis: 0.0 ± 0.0
1.224MetIle: 1.224 ± 0.835
0.612MetLys: 0.612 ± 0.721
2.448MetLeu: 2.448 ± 1.209
0.0MetMet: 0.0 ± 0.0
0.612MetAsn: 0.612 ± 0.439
0.612MetPro: 0.612 ± 0.523
0.612MetGln: 0.612 ± 0.523
0.612MetArg: 0.612 ± 0.666
4.896MetSer: 4.896 ± 1.026
0.612MetThr: 0.612 ± 0.439
0.0MetVal: 0.0 ± 0.0
0.612MetTrp: 0.612 ± 0.439
1.836MetTyr: 1.836 ± 1.038
0.0MetXaa: 0.0 ± 0.0
Asn
3.06AsnAla: 3.06 ± 1.351
0.0AsnCys: 0.0 ± 0.0
2.448AsnAsp: 2.448 ± 0.972
0.0AsnGlu: 0.0 ± 0.0
1.836AsnPhe: 1.836 ± 0.464
4.896AsnGly: 4.896 ± 2.098
0.612AsnHis: 0.612 ± 0.439
1.224AsnIle: 1.224 ± 0.537
2.448AsnLys: 2.448 ± 1.108
7.344AsnLeu: 7.344 ± 2.547
0.612AsnMet: 0.612 ± 0.666
4.896AsnAsn: 4.896 ± 2.156
1.836AsnPro: 1.836 ± 0.717
3.06AsnGln: 3.06 ± 0.751
3.672AsnArg: 3.672 ± 1.734
3.06AsnSer: 3.06 ± 1.255
3.06AsnThr: 3.06 ± 1.351
2.448AsnVal: 2.448 ± 1.754
0.0AsnTrp: 0.0 ± 0.0
1.224AsnTyr: 1.224 ± 0.773
0.0AsnXaa: 0.0 ± 0.0
Pro
1.836ProAla: 1.836 ± 0.464
1.224ProCys: 1.224 ± 0.817
4.896ProAsp: 4.896 ± 1.778
1.224ProGlu: 1.224 ± 1.138
1.836ProPhe: 1.836 ± 0.762
0.612ProGly: 0.612 ± 0.439
0.612ProHis: 0.612 ± 0.523
3.672ProIle: 3.672 ± 1.614
0.612ProLys: 0.612 ± 0.666
6.732ProLeu: 6.732 ± 1.714
0.612ProMet: 0.612 ± 0.523
1.224ProAsn: 1.224 ± 0.877
0.612ProPro: 0.612 ± 0.721
2.448ProGln: 2.448 ± 1.074
1.836ProArg: 1.836 ± 0.762
7.344ProSer: 7.344 ± 2.179
2.448ProThr: 2.448 ± 1.545
1.836ProVal: 1.836 ± 0.836
0.0ProTrp: 0.0 ± 0.0
2.448ProTyr: 2.448 ± 1.754
0.0ProXaa: 0.0 ± 0.0
Gln
2.448GlnAla: 2.448 ± 1.458
0.0GlnCys: 0.0 ± 0.0
1.224GlnAsp: 1.224 ± 0.537
3.06GlnGlu: 3.06 ± 2.617
3.06GlnPhe: 3.06 ± 0.751
1.224GlnGly: 1.224 ± 0.537
0.612GlnHis: 0.612 ± 0.523
1.224GlnIle: 1.224 ± 0.779
1.836GlnLys: 1.836 ± 1.57
1.836GlnLeu: 1.836 ± 0.966
0.612GlnMet: 0.612 ± 0.666
2.448GlnAsn: 2.448 ± 0.811
0.612GlnPro: 0.612 ± 0.439
3.672GlnGln: 3.672 ± 2.481
6.12GlnArg: 6.12 ± 2.638
4.896GlnSer: 4.896 ± 1.609
1.836GlnThr: 1.836 ± 0.966
1.224GlnVal: 1.224 ± 0.877
0.0GlnTrp: 0.0 ± 0.0
1.224GlnTyr: 1.224 ± 1.047
0.0GlnXaa: 0.0 ± 0.0
Arg
8.568ArgAla: 8.568 ± 1.255
0.612ArgCys: 0.612 ± 0.757
1.836ArgAsp: 1.836 ± 0.464
4.896ArgGlu: 4.896 ± 1.909
2.448ArgPhe: 2.448 ± 0.863
2.448ArgGly: 2.448 ± 0.644
0.0ArgHis: 0.0 ± 0.0
2.448ArgIle: 2.448 ± 0.874
1.224ArgLys: 1.224 ± 1.514
6.732ArgLeu: 6.732 ± 1.326
4.896ArgMet: 4.896 ± 1.427
3.06ArgAsn: 3.06 ± 0.892
3.06ArgPro: 3.06 ± 0.892
1.836ArgGln: 1.836 ± 0.966
1.224ArgArg: 1.224 ± 0.566
6.12ArgSer: 6.12 ± 1.571
0.0ArgThr: 0.0 ± 0.0
1.224ArgVal: 1.224 ± 0.718
0.0ArgTrp: 0.0 ± 0.0
3.672ArgTyr: 3.672 ± 0.729
0.0ArgXaa: 0.0 ± 0.0
Ser
7.344SerAla: 7.344 ± 2.265
1.224SerCys: 1.224 ± 0.566
6.12SerAsp: 6.12 ± 1.247
7.344SerGlu: 7.344 ± 2.875
6.12SerPhe: 6.12 ± 1.87
6.12SerGly: 6.12 ± 1.805
3.06SerHis: 3.06 ± 1.692
6.732SerIle: 6.732 ± 1.727
3.06SerLys: 3.06 ± 1.284
6.12SerLeu: 6.12 ± 1.404
2.448SerMet: 2.448 ± 1.074
3.06SerAsn: 3.06 ± 1.502
4.284SerPro: 4.284 ± 2.273
5.508SerGln: 5.508 ± 2.898
5.508SerArg: 5.508 ± 1.055
15.912SerSer: 15.912 ± 3.863
7.344SerThr: 7.344 ± 1.241
3.672SerVal: 3.672 ± 1.125
0.0SerTrp: 0.0 ± 0.0
3.06SerTyr: 3.06 ± 1.419
0.0SerXaa: 0.0 ± 0.0
Thr
5.508ThrAla: 5.508 ± 1.958
0.612ThrCys: 0.612 ± 0.439
3.06ThrAsp: 3.06 ± 0.977
0.612ThrGlu: 0.612 ± 0.523
3.672ThrPhe: 3.672 ± 1.312
4.896ThrGly: 4.896 ± 1.722
0.0ThrHis: 0.0 ± 0.0
3.06ThrIle: 3.06 ± 0.979
1.224ThrLys: 1.224 ± 0.537
5.508ThrLeu: 5.508 ± 1.725
1.836ThrMet: 1.836 ± 1.778
1.836ThrAsn: 1.836 ± 0.94
3.672ThrPro: 3.672 ± 1.273
3.06ThrGln: 3.06 ± 1.473
4.284ThrArg: 4.284 ± 1.775
6.732ThrSer: 6.732 ± 2.019
0.612ThrThr: 0.612 ± 0.439
1.836ThrVal: 1.836 ± 0.829
0.0ThrTrp: 0.0 ± 0.0
5.508ThrTyr: 5.508 ± 1.55
0.0ThrXaa: 0.0 ± 0.0
Val
5.508ValAla: 5.508 ± 1.501
2.448ValCys: 2.448 ± 1.957
4.284ValAsp: 4.284 ± 2.18
3.06ValGlu: 3.06 ± 1.624
2.448ValPhe: 2.448 ± 1.108
0.612ValGly: 0.612 ± 0.523
1.224ValHis: 1.224 ± 0.723
0.612ValIle: 0.612 ± 0.439
4.284ValLys: 4.284 ± 2.237
4.284ValLeu: 4.284 ± 1.42
1.224ValMet: 1.224 ± 0.803
0.612ValAsn: 0.612 ± 0.523
4.896ValPro: 4.896 ± 2.056
0.0ValGln: 0.0 ± 0.0
2.448ValArg: 2.448 ± 0.547
4.284ValSer: 4.284 ± 0.829
1.836ValThr: 1.836 ± 0.906
3.06ValVal: 3.06 ± 1.082
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.612TrpGlu: 0.612 ± 0.757
0.0TrpPhe: 0.0 ± 0.0
0.612TrpGly: 0.612 ± 0.439
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.224TrpLeu: 1.224 ± 1.332
0.0TrpMet: 0.0 ± 0.0
1.224TrpAsn: 1.224 ± 0.537
0.0TrpPro: 0.0 ± 0.0
1.224TrpGln: 1.224 ± 0.537
1.836TrpArg: 1.836 ± 0.829
0.612TrpSer: 0.612 ± 0.523
0.612TrpThr: 0.612 ± 0.439
0.612TrpVal: 0.612 ± 0.439
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.508TyrAla: 5.508 ± 1.991
1.836TyrCys: 1.836 ± 1.329
1.836TyrAsp: 1.836 ± 1.514
0.0TyrGlu: 0.0 ± 0.0
3.672TyrPhe: 3.672 ± 1.181
4.896TyrGly: 4.896 ± 1.651
1.836TyrHis: 1.836 ± 0.762
4.284TyrIle: 4.284 ± 1.346
0.612TyrLys: 0.612 ± 0.666
4.284TyrLeu: 4.284 ± 1.591
0.612TyrMet: 0.612 ± 0.439
1.224TyrAsn: 1.224 ± 1.002
0.612TyrPro: 0.612 ± 0.757
4.284TyrGln: 4.284 ± 1.214
2.448TyrArg: 2.448 ± 0.889
5.508TyrSer: 5.508 ± 1.927
1.836TyrThr: 1.836 ± 1.038
2.448TyrVal: 2.448 ± 1.798
0.0TyrTrp: 0.0 ± 0.0
3.672TyrTyr: 3.672 ± 1.369
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1635 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski