Amino acid dipepetide frequency for Thiomonas delicata (Thiomonas cuprina)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.401AlaAla: 19.401 ± 0.216	1.456AlaCys: 1.456 ± 0.04	6.452AlaAsp: 6.452 ± 0.077	6.743AlaGlu: 6.743 ± 0.079	3.917AlaPhe: 3.917 ± 0.062	10.919AlaGly: 10.919 ± 0.119	3.108AlaHis: 3.108 ± 0.06	5.142AlaIle: 5.142 ± 0.082	3.306AlaLys: 3.306 ± 0.067	16.121AlaLeu: 16.121 ± 0.161	3.873AlaMet: 3.873 ± 0.057	2.647AlaAsn: 2.647 ± 0.055	6.492AlaPro: 6.492 ± 0.086	7.14AlaGln: 7.14 ± 0.105	9.993AlaArg: 9.993 ± 0.108	6.977AlaSer: 6.977 ± 0.087	5.643AlaThr: 5.643 ± 0.071	9.155AlaVal: 9.155 ± 0.11	2.25AlaTrp: 2.25 ± 0.05	2.723AlaTyr: 2.723 ± 0.051	0.004AlaXaa: 0.004 ± 0.002
Cys	1.357CysAla: 1.357 ± 0.036	0.141CysCys: 0.141 ± 0.012	0.539CysAsp: 0.539 ± 0.024	0.495CysGlu: 0.495 ± 0.02	0.291CysPhe: 0.291 ± 0.016	1.09CysGly: 1.09 ± 0.032	0.297CysHis: 0.297 ± 0.019	0.411CysIle: 0.411 ± 0.019	0.228CysLys: 0.228 ± 0.015	0.847CysLeu: 0.847 ± 0.029	0.211CysMet: 0.211 ± 0.015	0.262CysAsn: 0.262 ± 0.017	0.574CysPro: 0.574 ± 0.026	0.273CysGln: 0.273 ± 0.016	0.641CysArg: 0.641 ± 0.028	0.538CysSer: 0.538 ± 0.024	0.478CysThr: 0.478 ± 0.021	0.701CysVal: 0.701 ± 0.024	0.119CysTrp: 0.119 ± 0.009	0.173CysTyr: 0.173 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.823AspAla: 7.823 ± 0.107	0.512AspCys: 0.512 ± 0.022	2.706AspAsp: 2.706 ± 0.055	2.63AspGlu: 2.63 ± 0.045	1.994AspPhe: 1.994 ± 0.042	4.203AspGly: 4.203 ± 0.056	1.207AspHis: 1.207 ± 0.033	2.425AspIle: 2.425 ± 0.05	1.531AspLys: 1.531 ± 0.046	5.666AspLeu: 5.666 ± 0.075	1.259AspMet: 1.259 ± 0.037	1.074AspAsn: 1.074 ± 0.034	3.223AspPro: 3.223 ± 0.05	1.595AspGln: 1.595 ± 0.039	3.09AspArg: 3.09 ± 0.058	2.052AspSer: 2.052 ± 0.052	2.4AspThr: 2.4 ± 0.044	3.891AspVal: 3.891 ± 0.065	0.994AspTrp: 0.994 ± 0.032	1.281AspTyr: 1.281 ± 0.036	0.001AspXaa: 0.001 ± 0.001
Glu	6.402GluAla: 6.402 ± 0.089	0.339GluCys: 0.339 ± 0.019	2.049GluAsp: 2.049 ± 0.05	1.886GluGlu: 1.886 ± 0.044	1.617GluPhe: 1.617 ± 0.041	3.317GluGly: 3.317 ± 0.064	1.481GluHis: 1.481 ± 0.042	2.363GluIle: 2.363 ± 0.053	1.396GluLys: 1.396 ± 0.042	5.558GluLeu: 5.558 ± 0.08	1.139GluMet: 1.139 ± 0.033	1.199GluAsn: 1.199 ± 0.033	2.619GluPro: 2.619 ± 0.049	2.772GluGln: 2.772 ± 0.051	4.465GluArg: 4.465 ± 0.078	2.325GluSer: 2.325 ± 0.044	2.449GluThr: 2.449 ± 0.055	3.439GluVal: 3.439 ± 0.062	0.604GluTrp: 0.604 ± 0.023	0.848GluTyr: 0.848 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.24PheAla: 4.24 ± 0.066	0.352PheCys: 0.352 ± 0.018	2.33PheAsp: 2.33 ± 0.049	1.89PheGlu: 1.89 ± 0.049	1.247PhePhe: 1.247 ± 0.039	3.257PheGly: 3.257 ± 0.057	0.786PheHis: 0.786 ± 0.028	1.546PheIle: 1.546 ± 0.044	0.996PheLys: 0.996 ± 0.033	3.01PheLeu: 3.01 ± 0.062	0.791PheMet: 0.791 ± 0.023	1.023PheAsn: 1.023 ± 0.031	1.469PhePro: 1.469 ± 0.037	1.024PheGln: 1.024 ± 0.029	1.779PheArg: 1.779 ± 0.037	1.952PheSer: 1.952 ± 0.045	1.789PheThr: 1.789 ± 0.042	2.572PheVal: 2.572 ± 0.047	0.532PheTrp: 0.532 ± 0.025	0.868PheTyr: 0.868 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.409GlyAla: 9.409 ± 0.096	0.949GlyCys: 0.949 ± 0.032	3.797GlyAsp: 3.797 ± 0.064	3.934GlyGlu: 3.934 ± 0.06	3.189GlyPhe: 3.189 ± 0.051	6.569GlyGly: 6.569 ± 0.093	2.218GlyHis: 2.218 ± 0.05	3.858GlyIle: 3.858 ± 0.066	2.977GlyLys: 2.977 ± 0.058	9.627GlyLeu: 9.627 ± 0.096	2.481GlyMet: 2.481 ± 0.058	1.97GlyAsn: 1.97 ± 0.048	3.359GlyPro: 3.359 ± 0.06	3.57GlyGln: 3.57 ± 0.062	5.717GlyArg: 5.717 ± 0.08	4.36GlySer: 4.36 ± 0.061	4.038GlyThr: 4.038 ± 0.055	6.479GlyVal: 6.479 ± 0.088	1.504GlyTrp: 1.504 ± 0.036	2.207GlyTyr: 2.207 ± 0.045	0.001GlyXaa: 0.001 ± 0.001
His	3.739HisAla: 3.739 ± 0.057	0.285HisCys: 0.285 ± 0.015	1.455HisAsp: 1.455 ± 0.038	1.125HisGlu: 1.125 ± 0.03	0.871HisPhe: 0.871 ± 0.027	2.406HisGly: 2.406 ± 0.053	0.75HisHis: 0.75 ± 0.027	1.037HisIle: 1.037 ± 0.035	0.559HisLys: 0.559 ± 0.021	2.623HisLeu: 2.623 ± 0.041	0.546HisMet: 0.546 ± 0.023	0.542HisAsn: 0.542 ± 0.021	1.74HisPro: 1.74 ± 0.045	0.81HisGln: 0.81 ± 0.025	1.774HisArg: 1.774 ± 0.048	0.981HisSer: 0.981 ± 0.029	1.084HisThr: 1.084 ± 0.033	1.767HisVal: 1.767 ± 0.039	0.45HisTrp: 0.45 ± 0.02	0.622HisTyr: 0.622 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.023IleAla: 6.023 ± 0.074	0.413IleCys: 0.413 ± 0.019	2.885IleAsp: 2.885 ± 0.05	2.777IleGlu: 2.777 ± 0.053	1.221IlePhe: 1.221 ± 0.042	4.018IleGly: 4.018 ± 0.072	0.985IleHis: 0.985 ± 0.03	1.526IleIle: 1.526 ± 0.042	1.291IleLys: 1.291 ± 0.036	3.624IleLeu: 3.624 ± 0.065	0.787IleMet: 0.787 ± 0.03	1.266IleAsn: 1.266 ± 0.036	2.179IlePro: 2.179 ± 0.044	1.434IleGln: 1.434 ± 0.034	2.713IleArg: 2.713 ± 0.052	2.308IleSer: 2.308 ± 0.052	2.249IleThr: 2.249 ± 0.048	3.318IleVal: 3.318 ± 0.057	0.511IleTrp: 0.511 ± 0.022	0.969IleTyr: 0.969 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.461LysAla: 3.461 ± 0.06	0.139LysCys: 0.139 ± 0.011	1.34LysAsp: 1.34 ± 0.041	1.062LysGlu: 1.062 ± 0.034	0.746LysPhe: 0.746 ± 0.029	2.02LysGly: 2.02 ± 0.052	0.586LysHis: 0.586 ± 0.028	1.276LysIle: 1.276 ± 0.036	1.042LysLys: 1.042 ± 0.04	3.247LysLeu: 3.247 ± 0.06	0.657LysMet: 0.657 ± 0.026	0.793LysAsn: 0.793 ± 0.03	2.171LysPro: 2.171 ± 0.049	1.128LysGln: 1.128 ± 0.035	2.116LysArg: 2.116 ± 0.046	1.612LysSer: 1.612 ± 0.034	1.821LysThr: 1.821 ± 0.042	2.036LysVal: 2.036 ± 0.05	0.281LysTrp: 0.281 ± 0.015	0.543LysTyr: 0.543 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.857LeuAla: 15.857 ± 0.168	0.988LeuCys: 0.988 ± 0.028	6.481LeuAsp: 6.481 ± 0.076	5.16LeuGlu: 5.16 ± 0.075	3.625LeuPhe: 3.625 ± 0.064	9.318LeuGly: 9.318 ± 0.101	2.819LeuHis: 2.819 ± 0.054	4.193LeuIle: 4.193 ± 0.067	3.0LeuLys: 3.0 ± 0.06	12.487LeuLeu: 12.487 ± 0.158	2.316LeuMet: 2.316 ± 0.048	2.502LeuAsn: 2.502 ± 0.052	6.67LeuPro: 6.67 ± 0.08	4.911LeuGln: 4.911 ± 0.078	9.369LeuArg: 9.369 ± 0.125	5.956LeuSer: 5.956 ± 0.078	4.978LeuThr: 4.978 ± 0.069	7.642LeuVal: 7.642 ± 0.082	1.506LeuTrp: 1.506 ± 0.039	2.139LeuTyr: 2.139 ± 0.043	0.003LeuXaa: 0.003 ± 0.001
Met	3.103MetAla: 3.103 ± 0.051	0.174MetCys: 0.174 ± 0.014	1.204MetAsp: 1.204 ± 0.035	0.982MetGlu: 0.982 ± 0.032	0.7MetPhe: 0.7 ± 0.023	1.743MetGly: 1.743 ± 0.046	0.707MetHis: 0.707 ± 0.027	0.88MetIle: 0.88 ± 0.029	0.77MetLys: 0.77 ± 0.027	2.854MetLeu: 2.854 ± 0.058	0.586MetMet: 0.586 ± 0.029	0.872MetAsn: 0.872 ± 0.028	1.708MetPro: 1.708 ± 0.038	1.389MetGln: 1.389 ± 0.036	2.134MetArg: 2.134 ± 0.045	1.513MetSer: 1.513 ± 0.036	1.433MetThr: 1.433 ± 0.035	1.569MetVal: 1.569 ± 0.042	0.22MetTrp: 0.22 ± 0.014	0.333MetTyr: 0.333 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.135AsnAla: 3.135 ± 0.058	0.245AsnCys: 0.245 ± 0.016	1.102AsnAsp: 1.102 ± 0.034	0.876AsnGlu: 0.876 ± 0.025	0.818AsnPhe: 0.818 ± 0.028	1.926AsnGly: 1.926 ± 0.048	0.545AsnHis: 0.545 ± 0.021	1.127AsnIle: 1.127 ± 0.033	0.689AsnLys: 0.689 ± 0.028	2.769AsnLeu: 2.769 ± 0.047	0.552AsnMet: 0.552 ± 0.024	0.62AsnAsn: 0.62 ± 0.032	2.062AsnPro: 2.062 ± 0.045	0.942AsnGln: 0.942 ± 0.032	1.625AsnArg: 1.625 ± 0.035	1.098AsnSer: 1.098 ± 0.035	1.354AsnThr: 1.354 ± 0.041	1.699AsnVal: 1.699 ± 0.039	0.415AsnTrp: 0.415 ± 0.02	0.629AsnTyr: 0.629 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.848ProAla: 7.848 ± 0.102	0.502ProCys: 0.502 ± 0.021	3.333ProAsp: 3.333 ± 0.058	3.194ProGlu: 3.194 ± 0.056	1.655ProPhe: 1.655 ± 0.042	5.214ProGly: 5.214 ± 0.074	1.332ProHis: 1.332 ± 0.035	2.075ProIle: 2.075 ± 0.042	1.485ProLys: 1.485 ± 0.037	5.478ProLeu: 5.478 ± 0.065	1.419ProMet: 1.419 ± 0.036	1.323ProAsn: 1.323 ± 0.036	3.148ProPro: 3.148 ± 0.064	2.768ProGln: 2.768 ± 0.052	3.572ProArg: 3.572 ± 0.059	2.99ProSer: 2.99 ± 0.055	2.662ProThr: 2.662 ± 0.049	4.074ProVal: 4.074 ± 0.064	0.905ProTrp: 0.905 ± 0.03	1.214ProTyr: 1.214 ± 0.035	0.002ProXaa: 0.002 ± 0.001
Gln	7.225GlnAla: 7.225 ± 0.108	0.319GlnCys: 0.319 ± 0.018	1.918GlnAsp: 1.918 ± 0.037	1.716GlnGlu: 1.716 ± 0.042	1.342GlnPhe: 1.342 ± 0.032	3.564GlnGly: 3.564 ± 0.06	1.114GlnHis: 1.114 ± 0.031	1.967GlnIle: 1.967 ± 0.047	1.0GlnLys: 1.0 ± 0.033	4.252GlnLeu: 4.252 ± 0.065	0.96GlnMet: 0.96 ± 0.03	1.008GlnAsn: 1.008 ± 0.029	2.693GlnPro: 2.693 ± 0.046	2.28GlnGln: 2.28 ± 0.059	3.768GlnArg: 3.768 ± 0.064	2.24GlnSer: 2.24 ± 0.054	2.401GlnThr: 2.401 ± 0.051	3.047GlnVal: 3.047 ± 0.058	0.681GlnTrp: 0.681 ± 0.023	0.818GlnTyr: 0.818 ± 0.027	0.003GlnXaa: 0.003 ± 0.002
Arg	8.745ArgAla: 8.745 ± 0.102	0.696ArgCys: 0.696 ± 0.026	3.824ArgAsp: 3.824 ± 0.06	4.239ArgGlu: 4.239 ± 0.074	2.728ArgPhe: 2.728 ± 0.053	4.95ArgGly: 4.95 ± 0.074	2.186ArgHis: 2.186 ± 0.048	3.74ArgIle: 3.74 ± 0.059	2.212ArgLys: 2.212 ± 0.057	8.814ArgLeu: 8.814 ± 0.116	2.072ArgMet: 2.072 ± 0.044	1.816ArgAsn: 1.816 ± 0.043	3.758ArgPro: 3.758 ± 0.061	3.467ArgGln: 3.467 ± 0.059	5.871ArgArg: 5.871 ± 0.089	3.422ArgSer: 3.422 ± 0.06	3.217ArgThr: 3.217 ± 0.053	5.172ArgVal: 5.172 ± 0.065	1.268ArgTrp: 1.268 ± 0.045	1.823ArgTyr: 1.823 ± 0.037	0.001ArgXaa: 0.001 ± 0.001
Ser	6.445SerAla: 6.445 ± 0.086	0.515SerCys: 0.515 ± 0.024	2.282SerAsp: 2.282 ± 0.046	2.135SerGlu: 2.135 ± 0.048	1.817SerPhe: 1.817 ± 0.041	5.089SerGly: 5.089 ± 0.079	1.255SerHis: 1.255 ± 0.033	2.248SerIle: 2.248 ± 0.045	1.36SerLys: 1.36 ± 0.032	5.63SerLeu: 5.63 ± 0.08	1.427SerMet: 1.427 ± 0.036	1.281SerAsn: 1.281 ± 0.039	3.001SerPro: 3.001 ± 0.057	1.939SerGln: 1.939 ± 0.044	3.63SerArg: 3.63 ± 0.056	3.075SerSer: 3.075 ± 0.051	2.878SerThr: 2.878 ± 0.059	3.598SerVal: 3.598 ± 0.058	0.78SerTrp: 0.78 ± 0.028	1.143SerTyr: 1.143 ± 0.032	0.001SerXaa: 0.001 ± 0.001
Thr	5.827ThrAla: 5.827 ± 0.079	0.427ThrCys: 0.427 ± 0.021	2.281ThrAsp: 2.281 ± 0.044	2.138ThrGlu: 2.138 ± 0.048	1.526ThrPhe: 1.526 ± 0.044	4.266ThrGly: 4.266 ± 0.071	1.229ThrHis: 1.229 ± 0.032	1.967ThrIle: 1.967 ± 0.051	1.117ThrLys: 1.117 ± 0.033	6.226ThrLeu: 6.226 ± 0.078	1.056ThrMet: 1.056 ± 0.033	1.122ThrAsn: 1.122 ± 0.036	3.47ThrPro: 3.47 ± 0.056	2.151ThrGln: 2.151 ± 0.049	3.399ThrArg: 3.399 ± 0.055	2.52ThrSer: 2.52 ± 0.051	2.618ThrThr: 2.618 ± 0.051	3.786ThrVal: 3.786 ± 0.057	0.732ThrTrp: 0.732 ± 0.028	1.034ThrTyr: 1.034 ± 0.033	0.001ThrXaa: 0.001 ± 0.001
Val	8.774ValAla: 8.774 ± 0.113	0.786ValCys: 0.786 ± 0.027	3.919ValAsp: 3.919 ± 0.061	3.847ValGlu: 3.847 ± 0.062	2.66ValPhe: 2.66 ± 0.047	5.263ValGly: 5.263 ± 0.079	1.696ValHis: 1.696 ± 0.04	3.162ValIle: 3.162 ± 0.053	2.044ValLys: 2.044 ± 0.05	8.541ValLeu: 8.541 ± 0.096	1.879ValMet: 1.879 ± 0.044	1.927ValAsn: 1.927 ± 0.04	3.87ValPro: 3.87 ± 0.057	3.113ValGln: 3.113 ± 0.051	5.383ValArg: 5.383 ± 0.082	3.755ValSer: 3.755 ± 0.067	3.432ValThr: 3.432 ± 0.062	5.879ValVal: 5.879 ± 0.078	1.051ValTrp: 1.051 ± 0.033	1.515ValTyr: 1.515 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.629TrpAla: 1.629 ± 0.042	0.175TrpCys: 0.175 ± 0.011	0.616TrpAsp: 0.616 ± 0.023	0.542TrpGlu: 0.542 ± 0.022	0.577TrpPhe: 0.577 ± 0.025	1.019TrpGly: 1.019 ± 0.034	0.41TrpHis: 0.41 ± 0.018	0.695TrpIle: 0.695 ± 0.025	0.464TrpLys: 0.464 ± 0.021	2.252TrpLeu: 2.252 ± 0.055	0.491TrpMet: 0.491 ± 0.019	0.427TrpAsn: 0.427 ± 0.02	0.818TrpPro: 0.818 ± 0.028	0.75TrpGln: 0.75 ± 0.026	1.393TrpArg: 1.393 ± 0.038	0.784TrpSer: 0.784 ± 0.026	0.725TrpThr: 0.725 ± 0.028	1.095TrpVal: 1.095 ± 0.035	0.282TrpTrp: 0.282 ± 0.017	0.288TrpTyr: 0.288 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.016TyrAla: 3.016 ± 0.054	0.253TyrCys: 0.253 ± 0.015	1.044TyrAsp: 1.044 ± 0.034	0.896TyrGlu: 0.896 ± 0.026	0.91TyrPhe: 0.91 ± 0.03	2.061TyrGly: 2.061 ± 0.048	0.453TyrHis: 0.453 ± 0.018	0.856TyrIle: 0.856 ± 0.028	0.611TyrLys: 0.611 ± 0.023	2.291TyrLeu: 2.291 ± 0.051	0.372TyrMet: 0.372 ± 0.018	0.556TyrAsn: 0.556 ± 0.024	1.17TyrPro: 1.17 ± 0.031	0.856TyrGln: 0.856 ± 0.028	1.589TyrArg: 1.589 ± 0.035	1.069TyrSer: 1.069 ± 0.035	1.242TyrThr: 1.242 ± 0.035	1.579TyrVal: 1.579 ± 0.042	0.346TyrTrp: 0.346 ± 0.015	0.56TyrTyr: 0.56 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.001	0.001XaaGly: 0.001 ± 0.001	0.001XaaHis: 0.001 ± 0.001	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.003XaaArg: 0.003 ± 0.002	0.001XaaSer: 0.001 ± 0.001	0.003XaaThr: 0.003 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3683 proteins (1131413 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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