Amino acid dipepetide frequency for Acinetobacter rudis CIP 110305

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.131AlaAla: 8.131 ± 0.104	0.929AlaCys: 0.929 ± 0.029	4.419AlaAsp: 4.419 ± 0.085	5.54AlaGlu: 5.54 ± 0.079	3.332AlaPhe: 3.332 ± 0.06	5.832AlaGly: 5.832 ± 0.093	1.783AlaHis: 1.783 ± 0.039	5.988AlaIle: 5.988 ± 0.084	4.795AlaLys: 4.795 ± 0.072	9.965AlaLeu: 9.965 ± 0.104	2.492AlaMet: 2.492 ± 0.048	3.313AlaAsn: 3.313 ± 0.057	2.8AlaPro: 2.8 ± 0.06	5.165AlaGln: 5.165 ± 0.079	3.361AlaArg: 3.361 ± 0.06	4.764AlaSer: 4.764 ± 0.072	4.523AlaThr: 4.523 ± 0.067	5.883AlaVal: 5.883 ± 0.078	1.128AlaTrp: 1.128 ± 0.037	2.758AlaTyr: 2.758 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.776CysAla: 0.776 ± 0.029	0.174CysCys: 0.174 ± 0.014	0.493CysAsp: 0.493 ± 0.019	0.538CysGlu: 0.538 ± 0.023	0.514CysPhe: 0.514 ± 0.024	0.769CysGly: 0.769 ± 0.025	0.266CysHis: 0.266 ± 0.017	0.749CysIle: 0.749 ± 0.027	0.423CysLys: 0.423 ± 0.017	1.113CysLeu: 1.113 ± 0.036	0.249CysMet: 0.249 ± 0.016	0.387CysAsn: 0.387 ± 0.02	0.403CysPro: 0.403 ± 0.02	0.513CysGln: 0.513 ± 0.022	0.435CysArg: 0.435 ± 0.019	0.703CysSer: 0.703 ± 0.027	0.431CysThr: 0.431 ± 0.02	0.677CysVal: 0.677 ± 0.022	0.103CysTrp: 0.103 ± 0.009	0.341CysTyr: 0.341 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	4.293AspAla: 4.293 ± 0.068	0.48AspCys: 0.48 ± 0.021	2.46AspAsp: 2.46 ± 0.047	3.197AspGlu: 3.197 ± 0.061	2.476AspPhe: 2.476 ± 0.05	3.136AspGly: 3.136 ± 0.061	1.422AspHis: 1.422 ± 0.037	3.546AspIle: 3.546 ± 0.062	2.423AspLys: 2.423 ± 0.051	5.647AspLeu: 5.647 ± 0.077	1.126AspMet: 1.126 ± 0.032	1.822AspAsn: 1.822 ± 0.045	2.24AspPro: 2.24 ± 0.042	3.36AspGln: 3.36 ± 0.053	2.365AspArg: 2.365 ± 0.047	2.638AspSer: 2.638 ± 0.058	2.27AspThr: 2.27 ± 0.043	3.484AspVal: 3.484 ± 0.061	0.806AspTrp: 0.806 ± 0.031	2.056AspTyr: 2.056 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	4.468GluAla: 4.468 ± 0.077	0.404GluCys: 0.404 ± 0.021	2.515GluAsp: 2.515 ± 0.049	2.734GluGlu: 2.734 ± 0.056	2.117GluPhe: 2.117 ± 0.046	2.855GluGly: 2.855 ± 0.057	1.728GluHis: 1.728 ± 0.039	4.249GluIle: 4.249 ± 0.071	3.786GluLys: 3.786 ± 0.064	6.216GluLeu: 6.216 ± 0.083	1.464GluMet: 1.464 ± 0.041	2.76GluAsn: 2.76 ± 0.05	1.597GluPro: 1.597 ± 0.041	4.568GluGln: 4.568 ± 0.077	2.825GluArg: 2.825 ± 0.048	2.956GluSer: 2.956 ± 0.053	2.664GluThr: 2.664 ± 0.051	3.601GluVal: 3.601 ± 0.06	0.682GluTrp: 0.682 ± 0.029	1.813GluTyr: 1.813 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.803PheAla: 3.803 ± 0.067	0.494PheCys: 0.494 ± 0.023	2.653PheAsp: 2.653 ± 0.047	2.512PheGlu: 2.512 ± 0.049	1.886PhePhe: 1.886 ± 0.048	2.97PheGly: 2.97 ± 0.054	0.824PheHis: 0.824 ± 0.027	3.185PheIle: 3.185 ± 0.066	2.569PheLys: 2.569 ± 0.048	3.851PheLeu: 3.851 ± 0.076	1.075PheMet: 1.075 ± 0.032	2.346PheAsn: 2.346 ± 0.054	1.439PhePro: 1.439 ± 0.038	1.625PheGln: 1.625 ± 0.038	1.394PheArg: 1.394 ± 0.038	3.339PheSer: 3.339 ± 0.053	1.98PheThr: 1.98 ± 0.047	2.576PheVal: 2.576 ± 0.054	0.599PheTrp: 0.599 ± 0.027	1.573PheTyr: 1.573 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.978GlyAla: 4.978 ± 0.078	0.783GlyCys: 0.783 ± 0.028	2.88GlyAsp: 2.88 ± 0.057	3.497GlyGlu: 3.497 ± 0.062	3.169GlyPhe: 3.169 ± 0.057	4.407GlyGly: 4.407 ± 0.084	1.558GlyHis: 1.558 ± 0.037	4.626GlyIle: 4.626 ± 0.07	3.296GlyLys: 3.296 ± 0.058	7.077GlyLeu: 7.077 ± 0.096	1.803GlyMet: 1.803 ± 0.044	2.372GlyAsn: 2.372 ± 0.058	1.531GlyPro: 1.531 ± 0.038	3.421GlyGln: 3.421 ± 0.067	2.822GlyArg: 2.822 ± 0.057	3.864GlySer: 3.864 ± 0.058	3.163GlyThr: 3.163 ± 0.062	4.768GlyVal: 4.768 ± 0.066	0.901GlyTrp: 0.901 ± 0.028	2.458GlyTyr: 2.458 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.1HisAla: 2.1 ± 0.045	0.315HisCys: 0.315 ± 0.018	1.254HisAsp: 1.254 ± 0.036	1.187HisGlu: 1.187 ± 0.038	1.202HisPhe: 1.202 ± 0.032	1.541HisGly: 1.541 ± 0.039	0.78HisHis: 0.78 ± 0.031	1.709HisIle: 1.709 ± 0.039	0.954HisLys: 0.954 ± 0.031	2.663HisLeu: 2.663 ± 0.048	0.549HisMet: 0.549 ± 0.021	0.935HisAsn: 0.935 ± 0.024	1.321HisPro: 1.321 ± 0.037	1.499HisGln: 1.499 ± 0.037	1.089HisArg: 1.089 ± 0.035	1.458HisSer: 1.458 ± 0.034	1.05HisThr: 1.05 ± 0.031	1.471HisVal: 1.471 ± 0.037	0.383HisTrp: 0.383 ± 0.019	1.053HisTyr: 1.053 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.684IleAla: 6.684 ± 0.091	0.848IleCys: 0.848 ± 0.033	4.332IleAsp: 4.332 ± 0.064	4.773IleGlu: 4.773 ± 0.073	2.9IlePhe: 2.9 ± 0.063	4.755IleGly: 4.755 ± 0.07	1.61IleHis: 1.61 ± 0.042	4.176IleIle: 4.176 ± 0.07	3.604IleLys: 3.604 ± 0.06	6.506IleLeu: 6.506 ± 0.09	1.461IleMet: 1.461 ± 0.039	3.264IleAsn: 3.264 ± 0.06	2.8IlePro: 2.8 ± 0.057	3.585IleGln: 3.585 ± 0.063	2.957IleArg: 2.957 ± 0.05	4.72IleSer: 4.72 ± 0.06	3.404IleThr: 3.404 ± 0.053	4.315IleVal: 4.315 ± 0.075	0.784IleTrp: 0.784 ± 0.027	2.28IleTyr: 2.28 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.548LysAla: 4.548 ± 0.064	0.309LysCys: 0.309 ± 0.019	2.948LysAsp: 2.948 ± 0.063	2.642LysGlu: 2.642 ± 0.061	1.88LysPhe: 1.88 ± 0.042	2.806LysGly: 2.806 ± 0.057	1.313LysHis: 1.313 ± 0.036	4.004LysIle: 4.004 ± 0.063	3.383LysLys: 3.383 ± 0.073	5.26LysLeu: 5.26 ± 0.067	1.41LysMet: 1.41 ± 0.039	2.969LysAsn: 2.969 ± 0.069	2.05LysPro: 2.05 ± 0.047	3.386LysGln: 3.386 ± 0.061	2.433LysArg: 2.433 ± 0.045	3.279LysSer: 3.279 ± 0.063	3.283LysThr: 3.283 ± 0.059	3.669LysVal: 3.669 ± 0.065	0.581LysTrp: 0.581 ± 0.02	1.772LysTyr: 1.772 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	9.632LeuAla: 9.632 ± 0.102	1.162LeuCys: 1.162 ± 0.036	5.766LeuAsp: 5.766 ± 0.083	5.878LeuGlu: 5.878 ± 0.082	4.261LeuPhe: 4.261 ± 0.076	7.045LeuGly: 7.045 ± 0.091	2.221LeuHis: 2.221 ± 0.046	7.335LeuIle: 7.335 ± 0.105	6.488LeuLys: 6.488 ± 0.083	10.562LeuLeu: 10.562 ± 0.135	2.567LeuMet: 2.567 ± 0.051	5.419LeuAsn: 5.419 ± 0.071	4.385LeuPro: 4.385 ± 0.069	4.966LeuGln: 4.966 ± 0.084	4.147LeuArg: 4.147 ± 0.071	8.279LeuSer: 8.279 ± 0.103	5.63LeuThr: 5.63 ± 0.072	6.17LeuVal: 6.17 ± 0.082	1.186LeuTrp: 1.186 ± 0.033	2.967LeuTyr: 2.967 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.139MetAla: 2.139 ± 0.045	0.219MetCys: 0.219 ± 0.014	1.064MetAsp: 1.064 ± 0.032	0.844MetGlu: 0.844 ± 0.029	0.899MetPhe: 0.899 ± 0.033	1.649MetGly: 1.649 ± 0.039	0.563MetHis: 0.563 ± 0.021	1.63MetIle: 1.63 ± 0.044	1.311MetLys: 1.311 ± 0.036	2.726MetLeu: 2.726 ± 0.051	0.708MetMet: 0.708 ± 0.027	1.283MetAsn: 1.283 ± 0.032	1.131MetPro: 1.131 ± 0.032	1.651MetGln: 1.651 ± 0.038	1.131MetArg: 1.131 ± 0.032	1.967MetSer: 1.967 ± 0.048	1.522MetThr: 1.522 ± 0.043	1.533MetVal: 1.533 ± 0.04	0.227MetTrp: 0.227 ± 0.013	0.576MetTyr: 0.576 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.491AsnAla: 3.491 ± 0.062	0.411AsnCys: 0.411 ± 0.02	2.158AsnAsp: 2.158 ± 0.049	2.19AsnGlu: 2.19 ± 0.048	1.976AsnPhe: 1.976 ± 0.053	2.648AsnGly: 2.648 ± 0.066	1.117AsnHis: 1.117 ± 0.031	3.488AsnIle: 3.488 ± 0.058	2.562AsnLys: 2.562 ± 0.056	4.461AsnLeu: 4.461 ± 0.065	1.044AsnMet: 1.044 ± 0.033	2.359AsnAsn: 2.359 ± 0.058	2.133AsnPro: 2.133 ± 0.048	2.6AsnGln: 2.6 ± 0.048	1.838AsnArg: 1.838 ± 0.04	2.685AsnSer: 2.685 ± 0.056	2.517AsnThr: 2.517 ± 0.051	2.497AsnVal: 2.497 ± 0.051	0.584AsnTrp: 0.584 ± 0.026	1.65AsnTyr: 1.65 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	3.143ProAla: 3.143 ± 0.055	0.291ProCys: 0.291 ± 0.016	2.067ProAsp: 2.067 ± 0.046	2.94ProGlu: 2.94 ± 0.054	1.69ProPhe: 1.69 ± 0.043	1.69ProGly: 1.69 ± 0.043	0.888ProHis: 0.888 ± 0.029	2.675ProIle: 2.675 ± 0.046	2.136ProLys: 2.136 ± 0.045	3.704ProLeu: 3.704 ± 0.064	0.948ProMet: 0.948 ± 0.028	1.949ProAsn: 1.949 ± 0.042	0.984ProPro: 0.984 ± 0.035	1.931ProGln: 1.931 ± 0.039	1.466ProArg: 1.466 ± 0.041	2.398ProSer: 2.398 ± 0.052	2.154ProThr: 2.154 ± 0.044	2.836ProVal: 2.836 ± 0.052	0.48ProTrp: 0.48 ± 0.024	1.349ProTyr: 1.349 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	5.462GlnAla: 5.462 ± 0.088	0.523GlnCys: 0.523 ± 0.023	2.578GlnAsp: 2.578 ± 0.051	2.482GlnGlu: 2.482 ± 0.049	2.291GlnPhe: 2.291 ± 0.045	3.447GlnGly: 3.447 ± 0.064	2.077GlnHis: 2.077 ± 0.052	3.692GlnIle: 3.692 ± 0.057	2.737GlnLys: 2.737 ± 0.053	6.643GlnLeu: 6.643 ± 0.106	1.269GlnMet: 1.269 ± 0.036	2.272GlnAsn: 2.272 ± 0.045	2.075GlnPro: 2.075 ± 0.043	5.142GlnGln: 5.142 ± 0.12	2.829GlnArg: 2.829 ± 0.053	3.645GlnSer: 3.645 ± 0.066	2.603GlnThr: 2.603 ± 0.042	3.805GlnVal: 3.805 ± 0.07	0.772GlnTrp: 0.772 ± 0.025	2.043GlnTyr: 2.043 ± 0.05	0.0GlnXaa: 0.0 ± 0.0
Arg	3.332ArgAla: 3.332 ± 0.056	0.422ArgCys: 0.422 ± 0.018	2.146ArgAsp: 2.146 ± 0.045	2.533ArgGlu: 2.533 ± 0.059	2.159ArgPhe: 2.159 ± 0.049	2.397ArgGly: 2.397 ± 0.053	1.102ArgHis: 1.102 ± 0.035	3.06ArgIle: 3.06 ± 0.044	2.112ArgLys: 2.112 ± 0.044	4.908ArgLeu: 4.908 ± 0.078	1.051ArgMet: 1.051 ± 0.031	1.744ArgAsn: 1.744 ± 0.038	1.68ArgPro: 1.68 ± 0.044	2.455ArgGln: 2.455 ± 0.052	2.043ArgArg: 2.043 ± 0.054	2.458ArgSer: 2.458 ± 0.044	1.905ArgThr: 1.905 ± 0.041	2.855ArgVal: 2.855 ± 0.051	0.572ArgTrp: 0.572 ± 0.023	1.92ArgTyr: 1.92 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	5.243SerAla: 5.243 ± 0.076	0.607SerCys: 0.607 ± 0.025	2.992SerAsp: 2.992 ± 0.059	3.34SerGlu: 3.34 ± 0.049	2.967SerPhe: 2.967 ± 0.059	4.318SerGly: 4.318 ± 0.058	1.521SerHis: 1.521 ± 0.037	4.634SerIle: 4.634 ± 0.065	3.417SerLys: 3.417 ± 0.065	6.779SerLeu: 6.779 ± 0.09	1.676SerMet: 1.676 ± 0.044	2.859SerAsn: 2.859 ± 0.063	2.396SerPro: 2.396 ± 0.037	3.225SerGln: 3.225 ± 0.057	2.621SerArg: 2.621 ± 0.055	4.449SerSer: 4.449 ± 0.071	3.729SerThr: 3.729 ± 0.064	3.988SerVal: 3.988 ± 0.069	0.78SerTrp: 0.78 ± 0.027	2.266SerTyr: 2.266 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	5.017ThrAla: 5.017 ± 0.077	0.425ThrCys: 0.425 ± 0.018	2.591ThrAsp: 2.591 ± 0.055	3.066ThrGlu: 3.066 ± 0.053	1.894ThrPhe: 1.894 ± 0.044	3.914ThrGly: 3.914 ± 0.068	1.297ThrHis: 1.297 ± 0.034	3.268ThrIle: 3.268 ± 0.06	2.22ThrLys: 2.22 ± 0.051	5.663ThrLeu: 5.663 ± 0.078	1.037ThrMet: 1.037 ± 0.031	1.698ThrAsn: 1.698 ± 0.043	2.494ThrPro: 2.494 ± 0.05	3.038ThrGln: 3.038 ± 0.052	2.129ThrArg: 2.129 ± 0.044	2.946ThrSer: 2.946 ± 0.057	3.043ThrThr: 3.043 ± 0.06	3.643ThrVal: 3.643 ± 0.067	0.71ThrTrp: 0.71 ± 0.027	1.425ThrTyr: 1.425 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	5.837ValAla: 5.837 ± 0.094	0.692ValCys: 0.692 ± 0.023	3.609ValAsp: 3.609 ± 0.058	4.127ValGlu: 4.127 ± 0.073	2.814ValPhe: 2.814 ± 0.052	4.267ValGly: 4.267 ± 0.077	1.301ValHis: 1.301 ± 0.037	4.687ValIle: 4.687 ± 0.071	3.471ValLys: 3.471 ± 0.066	6.928ValLeu: 6.928 ± 0.089	1.763ValMet: 1.763 ± 0.04	2.802ValAsn: 2.802 ± 0.051	2.465ValPro: 2.465 ± 0.054	3.02ValGln: 3.02 ± 0.054	2.557ValArg: 2.557 ± 0.047	4.182ValSer: 4.182 ± 0.056	3.403ValThr: 3.403 ± 0.06	4.781ValVal: 4.781 ± 0.079	0.772ValTrp: 0.772 ± 0.026	1.94ValTyr: 1.94 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.825TrpAla: 0.825 ± 0.027	0.156TrpCys: 0.156 ± 0.012	0.575TrpAsp: 0.575 ± 0.025	0.481TrpGlu: 0.481 ± 0.027	0.632TrpPhe: 0.632 ± 0.025	0.79TrpGly: 0.79 ± 0.026	0.336TrpHis: 0.336 ± 0.014	0.933TrpIle: 0.933 ± 0.03	0.643TrpLys: 0.643 ± 0.023	1.652TrpLeu: 1.652 ± 0.044	0.407TrpMet: 0.407 ± 0.02	0.509TrpAsn: 0.509 ± 0.022	0.4TrpPro: 0.4 ± 0.019	0.905TrpGln: 0.905 ± 0.028	0.632TrpArg: 0.632 ± 0.026	0.851TrpSer: 0.851 ± 0.032	0.584TrpThr: 0.584 ± 0.024	0.861TrpVal: 0.861 ± 0.027	0.166TrpTrp: 0.166 ± 0.012	0.419TrpTyr: 0.419 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.0TyrAla: 3.0 ± 0.057	0.413TyrCys: 0.413 ± 0.022	1.746TyrAsp: 1.746 ± 0.041	1.5TyrGlu: 1.5 ± 0.037	1.634TyrPhe: 1.634 ± 0.036	2.138TyrGly: 2.138 ± 0.045	0.807TyrHis: 0.807 ± 0.03	2.127TyrIle: 2.127 ± 0.05	1.594TyrLys: 1.594 ± 0.047	3.741TyrLeu: 3.741 ± 0.058	0.673TyrMet: 0.673 ± 0.025	1.346TyrAsn: 1.346 ± 0.045	1.394TyrPro: 1.394 ± 0.036	2.33TyrGln: 2.33 ± 0.052	1.781TyrArg: 1.781 ± 0.039	2.225TyrSer: 2.225 ± 0.048	1.66TyrThr: 1.66 ± 0.045	2.005TyrVal: 2.005 ± 0.043	0.544TyrTrp: 0.544 ± 0.023	1.169TyrTyr: 1.169 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3609 proteins (1134487 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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