Amino acid dipepetide frequency for Mustela putorius papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.634AlaAla: 3.634 ± 0.981
0.363AlaCys: 0.363 ± 0.315
1.09AlaAsp: 1.09 ± 0.655
5.087AlaGlu: 5.087 ± 1.386
2.18AlaPhe: 2.18 ± 1.513
2.907AlaGly: 2.907 ± 1.033
0.727AlaHis: 0.727 ± 0.609
3.634AlaIle: 3.634 ± 0.903
3.27AlaLys: 3.27 ± 0.858
3.27AlaLeu: 3.27 ± 1.207
0.363AlaMet: 0.363 ± 0.315
1.817AlaAsn: 1.817 ± 0.67
3.634AlaPro: 3.634 ± 1.481
2.18AlaGln: 2.18 ± 0.707
2.544AlaArg: 2.544 ± 1.103
4.36AlaSer: 4.36 ± 1.809
1.453AlaThr: 1.453 ± 0.565
1.453AlaVal: 1.453 ± 0.569
0.363AlaTrp: 0.363 ± 0.315
0.727AlaTyr: 0.727 ± 0.403
0.0AlaXaa: 0.0 ± 0.0
Cys
0.363CysAla: 0.363 ± 0.302
1.09CysCys: 1.09 ± 0.687
1.817CysAsp: 1.817 ± 0.521
0.727CysGlu: 0.727 ± 0.609
2.18CysPhe: 2.18 ± 0.622
1.453CysGly: 1.453 ± 0.803
0.363CysHis: 0.363 ± 0.461
1.817CysIle: 1.817 ± 1.032
1.817CysLys: 1.817 ± 0.829
1.09CysLeu: 1.09 ± 0.555
0.363CysMet: 0.363 ± 0.523
1.09CysAsn: 1.09 ± 0.967
2.18CysPro: 2.18 ± 0.634
0.727CysGln: 0.727 ± 0.505
1.453CysArg: 1.453 ± 0.474
2.544CysSer: 2.544 ± 0.904
1.817CysThr: 1.817 ± 1.037
2.544CysVal: 2.544 ± 1.569
1.09CysTrp: 1.09 ± 0.623
1.09CysTyr: 1.09 ± 0.773
0.0CysXaa: 0.0 ± 0.0
Asp
2.18AspAla: 2.18 ± 0.731
1.817AspCys: 1.817 ± 0.579
2.907AspAsp: 2.907 ± 1.04
3.634AspGlu: 3.634 ± 2.563
2.18AspPhe: 2.18 ± 0.724
4.724AspGly: 4.724 ± 0.85
1.09AspHis: 1.09 ± 0.51
3.634AspIle: 3.634 ± 1.097
2.544AspLys: 2.544 ± 1.37
3.997AspLeu: 3.997 ± 1.121
0.0AspMet: 0.0 ± 0.0
3.634AspAsn: 3.634 ± 1.225
3.634AspPro: 3.634 ± 2.218
1.09AspGln: 1.09 ± 0.6
1.09AspArg: 1.09 ± 0.797
3.997AspSer: 3.997 ± 1.317
4.36AspThr: 4.36 ± 1.432
3.27AspVal: 3.27 ± 0.763
1.09AspTrp: 1.09 ± 0.647
1.09AspTyr: 1.09 ± 0.307
0.0AspXaa: 0.0 ± 0.0
Glu
3.27GluAla: 3.27 ± 0.78
1.09GluCys: 1.09 ± 0.757
5.814GluAsp: 5.814 ± 3.22
9.811GluGlu: 9.811 ± 3.281
2.544GluPhe: 2.544 ± 0.836
10.901GluGly: 10.901 ± 4.567
0.727GluHis: 0.727 ± 0.525
2.18GluIle: 2.18 ± 0.8
0.727GluLys: 0.727 ± 0.609
5.814GluLeu: 5.814 ± 0.741
0.363GluMet: 0.363 ± 0.302
3.634GluAsn: 3.634 ± 0.779
2.907GluPro: 2.907 ± 0.925
3.27GluGln: 3.27 ± 0.933
1.817GluArg: 1.817 ± 0.6
5.087GluSer: 5.087 ± 0.879
4.36GluThr: 4.36 ± 1.168
3.997GluVal: 3.997 ± 0.728
0.727GluTrp: 0.727 ± 0.314
1.09GluTyr: 1.09 ± 0.681
0.0GluXaa: 0.0 ± 0.0
Phe
1.453PheAla: 1.453 ± 0.474
1.09PheCys: 1.09 ± 0.507
2.907PheAsp: 2.907 ± 0.42
4.724PheGlu: 4.724 ± 2.218
3.997PhePhe: 3.997 ± 1.669
3.634PheGly: 3.634 ± 0.602
0.0PheHis: 0.0 ± 0.0
2.907PheIle: 2.907 ± 1.404
2.18PheLys: 2.18 ± 1.028
3.997PheLeu: 3.997 ± 1.098
0.727PheMet: 0.727 ± 0.403
2.18PheAsn: 2.18 ± 0.831
1.453PhePro: 1.453 ± 0.555
2.18PheGln: 2.18 ± 0.698
3.634PheArg: 3.634 ± 0.669
2.18PheSer: 2.18 ± 0.533
1.817PheThr: 1.817 ± 0.649
2.907PheVal: 2.907 ± 0.926
1.453PheTrp: 1.453 ± 0.565
1.453PheTyr: 1.453 ± 0.485
0.0PheXaa: 0.0 ± 0.0
Gly
2.907GlyAla: 2.907 ± 0.719
2.18GlyCys: 2.18 ± 1.039
3.997GlyAsp: 3.997 ± 0.815
9.084GlyGlu: 9.084 ± 3.889
2.544GlyPhe: 2.544 ± 0.836
11.991GlyGly: 11.991 ± 4.25
0.727GlyHis: 0.727 ± 0.314
1.817GlyIle: 1.817 ± 0.836
3.997GlyLys: 3.997 ± 1.673
5.451GlyLeu: 5.451 ± 1.079
0.0GlyMet: 0.0 ± 0.0
5.451GlyAsn: 5.451 ± 1.303
6.177GlyPro: 6.177 ± 1.895
3.997GlyGln: 3.997 ± 2.084
7.267GlyArg: 7.267 ± 4.398
7.631GlySer: 7.631 ± 2.747
6.177GlyThr: 6.177 ± 1.138
2.907GlyVal: 2.907 ± 1.42
1.817GlyTrp: 1.817 ± 0.568
0.727GlyTyr: 0.727 ± 0.389
0.0GlyXaa: 0.0 ± 0.0
His
1.453HisAla: 1.453 ± 0.51
1.09HisCys: 1.09 ± 0.48
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.727HisPhe: 0.727 ± 0.389
0.363HisGly: 0.363 ± 0.339
1.09HisHis: 1.09 ± 0.53
1.09HisIle: 1.09 ± 0.759
0.363HisLys: 0.363 ± 0.315
1.09HisLeu: 1.09 ± 0.504
0.727HisMet: 0.727 ± 0.609
0.363HisAsn: 0.363 ± 0.461
1.453HisPro: 1.453 ± 0.962
0.727HisGln: 0.727 ± 0.604
0.0HisArg: 0.0 ± 0.0
1.09HisSer: 1.09 ± 0.372
0.363HisThr: 0.363 ± 0.452
0.727HisVal: 0.727 ± 0.403
0.727HisTrp: 0.727 ± 0.525
2.18HisTyr: 2.18 ± 0.533
0.0HisXaa: 0.0 ± 0.0
Ile
3.634IleAla: 3.634 ± 0.527
1.09IleCys: 1.09 ± 0.773
2.544IleAsp: 2.544 ± 0.981
2.18IleGlu: 2.18 ± 0.966
1.09IlePhe: 1.09 ± 0.835
3.634IleGly: 3.634 ± 1.224
0.0IleHis: 0.0 ± 0.0
3.27IleIle: 3.27 ± 1.463
1.453IleLys: 1.453 ± 0.937
2.907IleLeu: 2.907 ± 0.769
0.727IleMet: 0.727 ± 0.63
3.634IleAsn: 3.634 ± 1.386
2.907IlePro: 2.907 ± 1.027
0.0IleGln: 0.0 ± 0.0
1.817IleArg: 1.817 ± 0.699
4.36IleSer: 4.36 ± 0.9
2.907IleThr: 2.907 ± 1.241
3.997IleVal: 3.997 ± 1.006
0.363IleTrp: 0.363 ± 0.452
1.453IleTyr: 1.453 ± 0.482
0.0IleXaa: 0.0 ± 0.0
Lys
2.18LysAla: 2.18 ± 0.544
2.18LysCys: 2.18 ± 0.917
2.544LysAsp: 2.544 ± 0.778
1.817LysGlu: 1.817 ± 0.789
2.18LysPhe: 2.18 ± 1.066
2.544LysGly: 2.544 ± 0.562
2.18LysHis: 2.18 ± 0.496
0.727LysIle: 0.727 ± 0.493
5.087LysLys: 5.087 ± 1.448
3.634LysLeu: 3.634 ± 1.368
1.09LysMet: 1.09 ± 0.626
3.27LysAsn: 3.27 ± 0.7
0.727LysPro: 0.727 ± 0.609
1.817LysGln: 1.817 ± 0.854
4.36LysArg: 4.36 ± 1.128
5.087LysSer: 5.087 ± 1.51
1.453LysThr: 1.453 ± 0.677
2.907LysVal: 2.907 ± 1.079
0.363LysTrp: 0.363 ± 0.339
2.907LysTyr: 2.907 ± 1.021
0.0LysXaa: 0.0 ± 0.0
Leu
4.36LeuAla: 4.36 ± 0.901
1.817LeuCys: 1.817 ± 0.521
5.087LeuAsp: 5.087 ± 1.413
6.177LeuGlu: 6.177 ± 1.185
4.724LeuPhe: 4.724 ± 1.423
8.358LeuGly: 8.358 ± 1.472
1.09LeuHis: 1.09 ± 0.642
2.544LeuIle: 2.544 ± 1.081
3.997LeuLys: 3.997 ± 1.124
7.631LeuLeu: 7.631 ± 3.415
2.544LeuMet: 2.544 ± 0.843
2.18LeuAsn: 2.18 ± 1.059
2.907LeuPro: 2.907 ± 1.319
4.36LeuGln: 4.36 ± 1.557
5.087LeuArg: 5.087 ± 0.713
4.724LeuSer: 4.724 ± 0.92
5.087LeuThr: 5.087 ± 1.941
4.724LeuVal: 4.724 ± 1.498
0.0LeuTrp: 0.0 ± 0.0
2.544LeuTyr: 2.544 ± 0.502
0.0LeuXaa: 0.0 ± 0.0
Met
1.453MetAla: 1.453 ± 0.478
0.363MetCys: 0.363 ± 0.339
0.363MetAsp: 0.363 ± 0.302
0.727MetGlu: 0.727 ± 0.372
1.09MetPhe: 1.09 ± 0.681
0.363MetGly: 0.363 ± 0.302
0.0MetHis: 0.0 ± 0.0
1.09MetIle: 1.09 ± 0.838
0.727MetLys: 0.727 ± 0.509
1.453MetLeu: 1.453 ± 0.669
0.727MetMet: 0.727 ± 0.609
0.727MetAsn: 0.727 ± 0.403
1.09MetPro: 1.09 ± 0.927
1.09MetGln: 1.09 ± 0.696
0.727MetArg: 0.727 ± 0.314
1.09MetSer: 1.09 ± 0.623
0.727MetThr: 0.727 ± 0.604
2.544MetVal: 2.544 ± 1.46
0.0MetTrp: 0.0 ± 0.0
0.363MetTyr: 0.363 ± 0.339
0.0MetXaa: 0.0 ± 0.0
Asn
3.634AsnAla: 3.634 ± 1.45
0.727AsnCys: 0.727 ± 0.726
2.18AsnAsp: 2.18 ± 0.688
2.907AsnGlu: 2.907 ± 0.988
3.27AsnPhe: 3.27 ± 0.841
3.27AsnGly: 3.27 ± 0.736
0.727AsnHis: 0.727 ± 0.403
2.544AsnIle: 2.544 ± 0.964
2.907AsnLys: 2.907 ± 0.488
4.724AsnLeu: 4.724 ± 0.854
1.09AsnMet: 1.09 ± 0.71
2.907AsnAsn: 2.907 ± 0.836
2.544AsnPro: 2.544 ± 1.619
0.363AsnGln: 0.363 ± 0.339
3.27AsnArg: 3.27 ± 0.909
3.997AsnSer: 3.997 ± 0.668
3.27AsnThr: 3.27 ± 1.075
2.907AsnVal: 2.907 ± 0.488
0.0AsnTrp: 0.0 ± 0.0
0.727AsnTyr: 0.727 ± 0.607
0.0AsnXaa: 0.0 ± 0.0
Pro
2.544ProAla: 2.544 ± 1.184
1.09ProCys: 1.09 ± 0.6
4.36ProAsp: 4.36 ± 1.125
3.634ProGlu: 3.634 ± 1.016
1.453ProPhe: 1.453 ± 0.738
2.544ProGly: 2.544 ± 0.946
0.363ProHis: 0.363 ± 0.447
3.27ProIle: 3.27 ± 1.068
3.997ProLys: 3.997 ± 1.594
5.087ProLeu: 5.087 ± 1.414
0.727ProMet: 0.727 ± 0.524
3.27ProAsn: 3.27 ± 1.718
11.265ProPro: 11.265 ± 5.832
3.27ProGln: 3.27 ± 0.809
4.724ProArg: 4.724 ± 1.298
4.36ProSer: 4.36 ± 1.699
3.997ProThr: 3.997 ± 1.007
3.634ProVal: 3.634 ± 1.238
0.363ProTrp: 0.363 ± 0.315
1.453ProTyr: 1.453 ± 0.744
0.0ProXaa: 0.0 ± 0.0
Gln
1.453GlnAla: 1.453 ± 0.62
1.09GlnCys: 1.09 ± 0.552
2.544GlnAsp: 2.544 ± 0.623
3.634GlnGlu: 3.634 ± 1.102
1.453GlnPhe: 1.453 ± 0.62
2.907GlnGly: 2.907 ± 0.987
1.09GlnHis: 1.09 ± 0.78
1.817GlnIle: 1.817 ± 0.812
0.363GlnLys: 0.363 ± 0.339
2.907GlnLeu: 2.907 ± 0.91
1.09GlnMet: 1.09 ± 0.41
1.817GlnAsn: 1.817 ± 0.5
1.09GlnPro: 1.09 ± 0.835
2.907GlnGln: 2.907 ± 1.247
2.18GlnArg: 2.18 ± 1.12
2.907GlnSer: 2.907 ± 0.746
2.907GlnThr: 2.907 ± 1.241
2.907GlnVal: 2.907 ± 1.394
1.817GlnTrp: 1.817 ± 0.841
0.727GlnTyr: 0.727 ± 0.389
0.0GlnXaa: 0.0 ± 0.0
Arg
2.18ArgAla: 2.18 ± 0.897
1.453ArgCys: 1.453 ± 0.484
1.817ArgAsp: 1.817 ± 0.836
3.27ArgGlu: 3.27 ± 0.775
2.18ArgPhe: 2.18 ± 1.156
8.721ArgGly: 8.721 ± 5.301
1.453ArgHis: 1.453 ± 0.725
1.453ArgIle: 1.453 ± 0.67
3.634ArgLys: 3.634 ± 0.819
6.177ArgLeu: 6.177 ± 0.864
2.18ArgMet: 2.18 ± 0.679
1.453ArgAsn: 1.453 ± 1.001
3.27ArgPro: 3.27 ± 1.294
1.817ArgGln: 1.817 ± 0.521
4.724ArgArg: 4.724 ± 1.45
5.451ArgSer: 5.451 ± 0.62
2.18ArgThr: 2.18 ± 1.2
2.907ArgVal: 2.907 ± 0.882
0.363ArgTrp: 0.363 ± 0.452
0.727ArgTyr: 0.727 ± 0.496
0.0ArgXaa: 0.0 ± 0.0
Ser
1.817SerAla: 1.817 ± 0.699
2.907SerCys: 2.907 ± 1.343
4.724SerAsp: 4.724 ± 1.007
3.634SerGlu: 3.634 ± 0.797
3.997SerPhe: 3.997 ± 1.168
6.904SerGly: 6.904 ± 1.616
1.09SerHis: 1.09 ± 0.53
2.907SerIle: 2.907 ± 1.252
2.18SerLys: 2.18 ± 1.169
7.631SerLeu: 7.631 ± 1.305
1.09SerMet: 1.09 ± 0.457
3.634SerAsn: 3.634 ± 1.407
4.724SerPro: 4.724 ± 2.154
3.27SerGln: 3.27 ± 1.422
5.087SerArg: 5.087 ± 1.442
9.084SerSer: 9.084 ± 3.931
8.721SerThr: 8.721 ± 2.152
4.724SerVal: 4.724 ± 1.139
0.727SerTrp: 0.727 ± 0.314
3.27SerTyr: 3.27 ± 0.606
0.0SerXaa: 0.0 ± 0.0
Thr
1.817ThrAla: 1.817 ± 0.367
2.544ThrCys: 2.544 ± 1.702
2.907ThrAsp: 2.907 ± 1.107
3.634ThrGlu: 3.634 ± 1.51
3.634ThrPhe: 3.634 ± 1.171
3.997ThrGly: 3.997 ± 1.215
1.817ThrHis: 1.817 ± 0.881
3.997ThrIle: 3.997 ± 1.285
2.907ThrLys: 2.907 ± 1.251
2.544ThrLeu: 2.544 ± 1.116
1.453ThrMet: 1.453 ± 0.482
2.544ThrAsn: 2.544 ± 1.377
7.994ThrPro: 7.994 ± 1.949
2.18ThrGln: 2.18 ± 0.971
3.27ThrArg: 3.27 ± 0.922
5.087ThrSer: 5.087 ± 1.719
4.36ThrThr: 4.36 ± 1.475
5.814ThrVal: 5.814 ± 1.098
1.817ThrTrp: 1.817 ± 1.03
2.544ThrTyr: 2.544 ± 0.585
0.0ThrXaa: 0.0 ± 0.0
Val
2.907ValAla: 2.907 ± 1.074
1.453ValCys: 1.453 ± 0.754
2.544ValAsp: 2.544 ± 0.963
2.544ValGlu: 2.544 ± 1.032
2.907ValPhe: 2.907 ± 0.573
3.997ValGly: 3.997 ± 1.092
0.363ValHis: 0.363 ± 0.315
2.544ValIle: 2.544 ± 0.78
2.907ValLys: 2.907 ± 0.519
5.814ValLeu: 5.814 ± 1.657
0.363ValMet: 0.363 ± 0.315
2.18ValAsn: 2.18 ± 0.576
3.634ValPro: 3.634 ± 0.715
3.27ValGln: 3.27 ± 1.18
2.18ValArg: 2.18 ± 1.469
5.814ValSer: 5.814 ± 1.369
7.994ValThr: 7.994 ± 1.895
4.724ValVal: 4.724 ± 1.311
1.817ValTrp: 1.817 ± 0.888
1.817ValTyr: 1.817 ± 0.676
0.0ValXaa: 0.0 ± 0.0
Trp
0.363TrpAla: 0.363 ± 0.302
0.363TrpCys: 0.363 ± 0.315
0.363TrpAsp: 0.363 ± 0.339
1.817TrpGlu: 1.817 ± 1.47
0.727TrpPhe: 0.727 ± 0.314
1.817TrpGly: 1.817 ± 0.894
0.363TrpHis: 0.363 ± 0.452
0.363TrpIle: 0.363 ± 0.302
1.453TrpLys: 1.453 ± 0.474
1.453TrpLeu: 1.453 ± 0.693
0.363TrpMet: 0.363 ± 0.468
1.09TrpAsn: 1.09 ± 0.6
0.727TrpPro: 0.727 ± 0.372
0.0TrpGln: 0.0 ± 0.0
0.727TrpArg: 0.727 ± 0.607
1.09TrpSer: 1.09 ± 0.759
1.453TrpThr: 1.453 ± 0.474
0.727TrpVal: 0.727 ± 0.403
0.0TrpTrp: 0.0 ± 0.0
0.363TrpTyr: 0.363 ± 0.523
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.453TyrAla: 1.453 ± 0.474
1.817TyrCys: 1.817 ± 1.375
1.453TyrAsp: 1.453 ± 0.282
1.09TyrGlu: 1.09 ± 0.369
1.817TyrPhe: 1.817 ± 0.634
1.817TyrGly: 1.817 ± 0.664
0.363TyrHis: 0.363 ± 0.339
0.363TyrIle: 0.363 ± 0.523
2.544TyrLys: 2.544 ± 0.968
3.27TyrLeu: 3.27 ± 1.039
0.363TyrMet: 0.363 ± 0.302
1.453TyrAsn: 1.453 ± 0.73
1.09TyrPro: 1.09 ± 0.552
1.09TyrGln: 1.09 ± 0.307
1.453TyrArg: 1.453 ± 0.84
2.18TyrSer: 2.18 ± 0.831
1.453TyrThr: 1.453 ± 0.883
1.453TyrVal: 1.453 ± 0.484
0.727TyrTrp: 0.727 ± 0.372
2.18TyrTyr: 2.18 ± 0.919
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2753 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski