Amino acid dipepetide frequency for Chino del tomate Amazonas virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.268AlaAla: 2.268 ± 0.744
1.134AlaCys: 1.134 ± 0.92
0.0AlaAsp: 0.0 ± 0.0
1.134AlaGlu: 1.134 ± 1.14
0.0AlaPhe: 0.0 ± 0.0
1.134AlaGly: 1.134 ± 0.92
2.268AlaHis: 2.268 ± 1.798
4.535AlaIle: 4.535 ± 2.14
1.134AlaLys: 1.134 ± 1.427
4.535AlaLeu: 4.535 ± 1.872
2.268AlaMet: 2.268 ± 0.744
1.134AlaAsn: 1.134 ± 0.767
3.401AlaPro: 3.401 ± 1.647
2.268AlaGln: 2.268 ± 0.744
3.401AlaArg: 3.401 ± 1.487
3.401AlaSer: 3.401 ± 2.05
4.535AlaThr: 4.535 ± 2.862
2.268AlaVal: 2.268 ± 1.098
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.134CysAla: 1.134 ± 0.767
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.134CysGly: 1.134 ± 1.427
1.134CysHis: 1.134 ± 0.767
2.268CysIle: 2.268 ± 1.839
2.268CysLys: 2.268 ± 1.535
2.268CysLeu: 2.268 ± 0.744
0.0CysMet: 0.0 ± 0.0
1.134CysAsn: 1.134 ± 0.767
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.134CysArg: 1.134 ± 0.92
1.134CysSer: 1.134 ± 1.427
3.401CysThr: 3.401 ± 2.727
1.134CysVal: 1.134 ± 0.92
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
3.401AspAsp: 3.401 ± 2.657
1.134AspGlu: 1.134 ± 0.92
2.268AspPhe: 2.268 ± 0.744
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
3.401AspIle: 3.401 ± 4.282
2.268AspLys: 2.268 ± 1.098
3.401AspLeu: 3.401 ± 1.965
0.0AspMet: 0.0 ± 0.0
2.268AspAsn: 2.268 ± 1.45
1.134AspPro: 1.134 ± 0.767
3.401AspGln: 3.401 ± 1.513
3.401AspArg: 3.401 ± 1.487
4.535AspSer: 4.535 ± 1.117
1.134AspThr: 1.134 ± 1.427
1.134AspVal: 1.134 ± 0.92
1.134AspTrp: 1.134 ± 0.767
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.134GluAla: 1.134 ± 0.92
2.268GluCys: 2.268 ± 1.336
0.0GluAsp: 0.0 ± 0.0
2.268GluGlu: 2.268 ± 1.098
3.401GluPhe: 3.401 ± 0.986
2.268GluGly: 2.268 ± 1.45
0.0GluHis: 0.0 ± 0.0
1.134GluIle: 1.134 ± 1.14
0.0GluLys: 0.0 ± 0.0
6.803GluLeu: 6.803 ± 2.39
0.0GluMet: 0.0 ± 0.0
5.669GluAsn: 5.669 ± 3.373
3.401GluPro: 3.401 ± 2.759
1.134GluGln: 1.134 ± 0.92
1.134GluArg: 1.134 ± 0.767
3.401GluSer: 3.401 ± 1.647
3.401GluThr: 3.401 ± 1.513
2.268GluVal: 2.268 ± 1.535
1.134GluTrp: 1.134 ± 1.427
1.134GluTyr: 1.134 ± 0.767
0.0GluXaa: 0.0 ± 0.0
Phe
1.134PheAla: 1.134 ± 1.14
1.134PheCys: 1.134 ± 0.92
1.134PheAsp: 1.134 ± 0.92
1.134PheGlu: 1.134 ± 0.92
0.0PhePhe: 0.0 ± 0.0
1.134PheGly: 1.134 ± 0.92
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
4.535PheLys: 4.535 ± 1.117
3.401PheLeu: 3.401 ± 2.302
0.0PheMet: 0.0 ± 0.0
3.401PheAsn: 3.401 ± 0.966
4.535PhePro: 4.535 ± 2.195
4.535PheGln: 4.535 ± 1.595
2.268PheArg: 2.268 ± 1.098
2.268PheSer: 2.268 ± 1.535
2.268PheThr: 2.268 ± 1.336
1.134PheVal: 1.134 ± 0.767
3.401PheTrp: 3.401 ± 1.965
3.401PheTyr: 3.401 ± 2.759
0.0PheXaa: 0.0 ± 0.0
Gly
2.268GlyAla: 2.268 ± 1.839
2.268GlyCys: 2.268 ± 2.855
2.268GlyAsp: 2.268 ± 1.336
1.134GlyGlu: 1.134 ± 0.767
5.669GlyPhe: 5.669 ± 1.497
2.268GlyGly: 2.268 ± 0.744
2.268GlyHis: 2.268 ± 1.336
2.268GlyIle: 2.268 ± 0.744
9.07GlyLys: 9.07 ± 3.638
0.0GlyLeu: 0.0 ± 0.0
0.0GlyMet: 0.0 ± 0.0
2.268GlyAsn: 2.268 ± 0.744
2.268GlyPro: 2.268 ± 0.744
3.401GlyGln: 3.401 ± 1.487
3.401GlyArg: 3.401 ± 0.986
6.803GlySer: 6.803 ± 2.233
4.535GlyThr: 4.535 ± 1.117
5.669GlyVal: 5.669 ± 3.428
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.134HisAla: 1.134 ± 0.92
1.134HisCys: 1.134 ± 1.427
0.0HisAsp: 0.0 ± 0.0
1.134HisGlu: 1.134 ± 1.427
1.134HisPhe: 1.134 ± 0.767
3.401HisGly: 3.401 ± 0.986
3.401HisHis: 3.401 ± 1.647
3.401HisIle: 3.401 ± 1.517
1.134HisLys: 1.134 ± 1.14
2.268HisLeu: 2.268 ± 1.098
1.134HisMet: 1.134 ± 1.017
1.134HisAsn: 1.134 ± 1.14
3.401HisPro: 3.401 ± 1.647
2.268HisGln: 2.268 ± 1.381
4.535HisArg: 4.535 ± 2.901
1.134HisSer: 1.134 ± 0.767
4.535HisThr: 4.535 ± 1.36
3.401HisVal: 3.401 ± 1.965
1.134HisTrp: 1.134 ± 0.767
1.134HisTyr: 1.134 ± 0.767
0.0HisXaa: 0.0 ± 0.0
Ile
3.401IleAla: 3.401 ± 1.2
0.0IleCys: 0.0 ± 0.0
1.134IleAsp: 1.134 ± 1.427
0.0IleGlu: 0.0 ± 0.0
2.268IlePhe: 2.268 ± 2.855
3.401IleGly: 3.401 ± 0.986
0.0IleHis: 0.0 ± 0.0
5.669IleIle: 5.669 ± 3.837
4.535IleLys: 4.535 ± 2.704
5.669IleLeu: 5.669 ± 1.294
1.134IleMet: 1.134 ± 0.767
1.134IleAsn: 1.134 ± 1.14
1.134IlePro: 1.134 ± 0.767
3.401IleGln: 3.401 ± 1.517
5.669IleArg: 5.669 ± 2.03
11.338IleSer: 11.338 ± 1.302
4.535IleThr: 4.535 ± 1.977
2.268IleVal: 2.268 ± 0.744
3.401IleTrp: 3.401 ± 0.966
4.535IleTyr: 4.535 ± 1.117
0.0IleXaa: 0.0 ± 0.0
Lys
1.134LysAla: 1.134 ± 1.14
2.268LysCys: 2.268 ± 0.744
1.134LysAsp: 1.134 ± 0.767
2.268LysGlu: 2.268 ± 1.098
2.268LysPhe: 2.268 ± 1.381
3.401LysGly: 3.401 ± 1.2
1.134LysHis: 1.134 ± 0.767
3.401LysIle: 3.401 ± 2.05
2.268LysLys: 2.268 ± 1.336
3.401LysLeu: 3.401 ± 1.487
1.134LysMet: 1.134 ± 1.099
2.268LysAsn: 2.268 ± 1.839
4.535LysPro: 4.535 ± 3.07
2.268LysGln: 2.268 ± 1.535
6.803LysArg: 6.803 ± 2.04
4.535LysSer: 4.535 ± 1.009
4.535LysThr: 4.535 ± 3.07
3.401LysVal: 3.401 ± 2.759
0.0LysTrp: 0.0 ± 0.0
2.268LysTyr: 2.268 ± 0.744
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.134LeuCys: 1.134 ± 0.767
4.535LeuAsp: 4.535 ± 1.595
4.535LeuGlu: 4.535 ± 1.117
0.0LeuPhe: 0.0 ± 0.0
4.535LeuGly: 4.535 ± 1.117
3.401LeuHis: 3.401 ± 1.517
7.937LeuIle: 7.937 ± 2.969
5.669LeuLys: 5.669 ± 1.844
4.535LeuLeu: 4.535 ± 1.489
3.401LeuMet: 3.401 ± 1.3
4.535LeuAsn: 4.535 ± 3.438
5.669LeuPro: 5.669 ± 2.598
3.401LeuGln: 3.401 ± 1.647
7.937LeuArg: 7.937 ± 1.963
5.669LeuSer: 5.669 ± 3.837
2.268LeuThr: 2.268 ± 1.535
4.535LeuVal: 4.535 ± 1.533
0.0LeuTrp: 0.0 ± 0.0
3.401LeuTyr: 3.401 ± 2.359
0.0LeuXaa: 0.0 ± 0.0
Met
1.134MetAla: 1.134 ± 0.92
3.401MetCys: 3.401 ± 1.487
4.535MetAsp: 4.535 ± 1.533
1.134MetGlu: 1.134 ± 0.767
2.268MetPhe: 2.268 ± 1.839
1.134MetGly: 1.134 ± 0.767
2.268MetHis: 2.268 ± 0.744
1.134MetIle: 1.134 ± 0.92
0.0MetLys: 0.0 ± 0.0
1.134MetLeu: 1.134 ± 1.14
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.134MetPro: 1.134 ± 0.767
3.401MetGln: 3.401 ± 2.302
1.134MetArg: 1.134 ± 1.427
3.401MetSer: 3.401 ± 1.487
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.134MetTrp: 1.134 ± 0.767
1.134MetTyr: 1.134 ± 1.14
0.0MetXaa: 0.0 ± 0.0
Asn
2.268AsnAla: 2.268 ± 0.744
1.134AsnCys: 1.134 ± 0.767
1.134AsnAsp: 1.134 ± 0.92
2.268AsnGlu: 2.268 ± 1.839
1.134AsnPhe: 1.134 ± 1.14
4.535AsnGly: 4.535 ± 1.533
7.937AsnHis: 7.937 ± 3.538
2.268AsnIle: 2.268 ± 1.839
2.268AsnLys: 2.268 ± 1.798
3.401AsnLeu: 3.401 ± 2.102
1.134AsnMet: 1.134 ± 0.92
3.401AsnAsn: 3.401 ± 0.966
4.535AsnPro: 4.535 ± 1.066
1.134AsnGln: 1.134 ± 0.767
0.0AsnArg: 0.0 ± 0.0
6.803AsnSer: 6.803 ± 1.475
2.268AsnThr: 2.268 ± 1.336
2.268AsnVal: 2.268 ± 2.28
1.134AsnTrp: 1.134 ± 0.767
1.134AsnTyr: 1.134 ± 0.767
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.134ProCys: 1.134 ± 0.92
1.134ProAsp: 1.134 ± 0.767
2.268ProGlu: 2.268 ± 1.336
0.0ProPhe: 0.0 ± 0.0
3.401ProGly: 3.401 ± 1.487
3.401ProHis: 3.401 ± 2.302
3.401ProIle: 3.401 ± 1.647
3.401ProLys: 3.401 ± 2.302
4.535ProLeu: 4.535 ± 1.533
3.401ProMet: 3.401 ± 2.05
1.134ProAsn: 1.134 ± 0.767
2.268ProPro: 2.268 ± 1.336
7.937ProGln: 7.937 ± 4.266
3.401ProArg: 3.401 ± 1.2
9.07ProSer: 9.07 ± 3.559
2.268ProThr: 2.268 ± 1.535
2.268ProVal: 2.268 ± 0.744
0.0ProTrp: 0.0 ± 0.0
2.268ProTyr: 2.268 ± 1.839
0.0ProXaa: 0.0 ± 0.0
Gln
5.669GlnAla: 5.669 ± 0.782
0.0GlnCys: 0.0 ± 0.0
1.134GlnAsp: 1.134 ± 1.427
5.669GlnGlu: 5.669 ± 1.497
2.268GlnPhe: 2.268 ± 1.098
2.268GlnGly: 2.268 ± 1.336
1.134GlnHis: 1.134 ± 0.767
4.535GlnIle: 4.535 ± 2.133
3.401GlnLys: 3.401 ± 2.302
5.669GlnLeu: 5.669 ± 2.827
1.134GlnMet: 1.134 ± 1.385
1.134GlnAsn: 1.134 ± 0.92
3.401GlnPro: 3.401 ± 1.647
1.134GlnGln: 1.134 ± 0.767
2.268GlnArg: 2.268 ± 1.336
3.401GlnSer: 3.401 ± 2.657
1.134GlnThr: 1.134 ± 0.767
5.669GlnVal: 5.669 ± 2.336
0.0GlnTrp: 0.0 ± 0.0
1.134GlnTyr: 1.134 ± 0.92
0.0GlnXaa: 0.0 ± 0.0
Arg
4.535ArgAla: 4.535 ± 2.733
1.134ArgCys: 1.134 ± 0.767
4.535ArgAsp: 4.535 ± 1.36
3.401ArgGlu: 3.401 ± 0.986
6.803ArgPhe: 6.803 ± 1.975
4.535ArgGly: 4.535 ± 1.009
1.134ArgHis: 1.134 ± 1.14
3.401ArgIle: 3.401 ± 0.986
2.268ArgLys: 2.268 ± 1.098
4.535ArgLeu: 4.535 ± 1.872
1.134ArgMet: 1.134 ± 0.767
2.268ArgAsn: 2.268 ± 1.535
3.401ArgPro: 3.401 ± 1.487
1.134ArgGln: 1.134 ± 1.427
7.937ArgArg: 7.937 ± 5.021
6.803ArgSer: 6.803 ± 2.946
3.401ArgThr: 3.401 ± 1.513
5.669ArgVal: 5.669 ± 1.374
1.134ArgTrp: 1.134 ± 0.92
2.268ArgTyr: 2.268 ± 1.381
0.0ArgXaa: 0.0 ± 0.0
Ser
4.535SerAla: 4.535 ± 2.704
0.0SerCys: 0.0 ± 0.0
3.401SerAsp: 3.401 ± 1.965
2.268SerGlu: 2.268 ± 1.535
3.401SerPhe: 3.401 ± 1.647
7.937SerGly: 7.937 ± 1.695
4.535SerHis: 4.535 ± 2.901
7.937SerIle: 7.937 ± 1.966
5.669SerLys: 5.669 ± 2.598
6.803SerLeu: 6.803 ± 3.544
3.401SerMet: 3.401 ± 2.302
6.803SerAsn: 6.803 ± 2.401
6.803SerPro: 6.803 ± 1.972
3.401SerGln: 3.401 ± 1.647
6.803SerArg: 6.803 ± 3.026
9.07SerSer: 9.07 ± 3.059
7.937SerThr: 7.937 ± 2.466
5.669SerVal: 5.669 ± 2.256
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.401ThrAla: 3.401 ± 2.359
0.0ThrCys: 0.0 ± 0.0
2.268ThrAsp: 2.268 ± 1.098
3.401ThrGlu: 3.401 ± 0.966
4.535ThrPhe: 4.535 ± 3.07
4.535ThrGly: 4.535 ± 1.36
5.669ThrHis: 5.669 ± 4.128
2.268ThrIle: 2.268 ± 0.744
0.0ThrLys: 0.0 ± 0.0
2.268ThrLeu: 2.268 ± 0.744
2.268ThrMet: 2.268 ± 1.535
7.937ThrAsn: 7.937 ± 1.524
3.401ThrPro: 3.401 ± 2.05
2.268ThrGln: 2.268 ± 1.336
3.401ThrArg: 3.401 ± 1.487
5.669ThrSer: 5.669 ± 2.23
4.535ThrThr: 4.535 ± 2.196
3.401ThrVal: 3.401 ± 1.647
1.134ThrTrp: 1.134 ± 0.767
2.268ThrTyr: 2.268 ± 1.098
0.0ThrXaa: 0.0 ± 0.0
Val
2.268ValAla: 2.268 ± 1.535
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
3.401ValGlu: 3.401 ± 1.517
1.134ValPhe: 1.134 ± 0.92
2.268ValGly: 2.268 ± 1.839
1.134ValHis: 1.134 ± 1.427
3.401ValIle: 3.401 ± 2.102
2.268ValLys: 2.268 ± 1.839
3.401ValLeu: 3.401 ± 1.513
4.535ValMet: 4.535 ± 2.862
2.268ValAsn: 2.268 ± 0.744
1.134ValPro: 1.134 ± 0.767
4.535ValGln: 4.535 ± 1.117
3.401ValArg: 3.401 ± 2.759
4.535ValSer: 4.535 ± 1.009
4.535ValThr: 4.535 ± 2.761
1.134ValVal: 1.134 ± 0.92
1.134ValTrp: 1.134 ± 1.14
7.937ValTyr: 7.937 ± 2.572
0.0ValXaa: 0.0 ± 0.0
Trp
1.134TrpAla: 1.134 ± 0.767
0.0TrpCys: 0.0 ± 0.0
1.134TrpAsp: 1.134 ± 1.427
1.134TrpGlu: 1.134 ± 1.14
0.0TrpPhe: 0.0 ± 0.0
1.134TrpGly: 1.134 ± 0.767
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.268TrpLys: 2.268 ± 0.744
1.134TrpLeu: 1.134 ± 0.92
1.134TrpMet: 1.134 ± 0.92
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.134TrpGln: 1.134 ± 0.767
3.401TrpArg: 3.401 ± 0.986
0.0TrpSer: 0.0 ± 0.0
1.134TrpThr: 1.134 ± 1.14
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.134TrpTyr: 1.134 ± 0.767
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.268TyrAla: 2.268 ± 1.839
0.0TyrCys: 0.0 ± 0.0
1.134TyrAsp: 1.134 ± 0.92
2.268TyrGlu: 2.268 ± 1.839
2.268TyrPhe: 2.268 ± 1.381
3.401TyrGly: 3.401 ± 1.487
1.134TyrHis: 1.134 ± 1.14
2.268TyrIle: 2.268 ± 1.381
0.0TyrLys: 0.0 ± 0.0
7.937TyrLeu: 7.937 ± 2.5
1.134TyrMet: 1.134 ± 0.92
2.268TyrAsn: 2.268 ± 1.381
1.134TyrPro: 1.134 ± 0.767
1.134TyrGln: 1.134 ± 0.92
0.0TyrArg: 0.0 ± 0.0
3.401TyrSer: 3.401 ± 2.302
2.268TyrThr: 2.268 ± 1.098
1.134TyrVal: 1.134 ± 1.14
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (883 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski