Amino acid dipepetide frequency for Adhaeribacter soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.438AlaAla: 7.438 ± 0.109	0.699AlaCys: 0.699 ± 0.028	3.907AlaAsp: 3.907 ± 0.065	5.06AlaGlu: 5.06 ± 0.086	3.925AlaPhe: 3.925 ± 0.062	6.701AlaGly: 6.701 ± 0.097	1.196AlaHis: 1.196 ± 0.035	4.933AlaIle: 4.933 ± 0.067	4.364AlaLys: 4.364 ± 0.078	7.588AlaLeu: 7.588 ± 0.095	1.76AlaMet: 1.76 ± 0.035	3.894AlaAsn: 3.894 ± 0.075	3.128AlaPro: 3.128 ± 0.066	3.065AlaGln: 3.065 ± 0.047	3.021AlaArg: 3.021 ± 0.058	5.057AlaSer: 5.057 ± 0.09	5.28AlaThr: 5.28 ± 0.141	4.952AlaVal: 4.952 ± 0.067	0.814AlaTrp: 0.814 ± 0.028	2.788AlaTyr: 2.788 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.57CysAla: 0.57 ± 0.027	0.121CysCys: 0.121 ± 0.011	0.36CysAsp: 0.36 ± 0.016	0.423CysGlu: 0.423 ± 0.021	0.45CysPhe: 0.45 ± 0.019	0.72CysGly: 0.72 ± 0.03	0.192CysHis: 0.192 ± 0.015	0.488CysIle: 0.488 ± 0.017	0.4CysLys: 0.4 ± 0.019	0.735CysLeu: 0.735 ± 0.025	0.131CysMet: 0.131 ± 0.01	0.422CysAsn: 0.422 ± 0.019	0.402CysPro: 0.402 ± 0.02	0.29CysGln: 0.29 ± 0.014	0.364CysArg: 0.364 ± 0.018	0.625CysSer: 0.625 ± 0.035	0.542CysThr: 0.542 ± 0.028	0.413CysVal: 0.413 ± 0.018	0.084CysTrp: 0.084 ± 0.007	0.257CysTyr: 0.257 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.526AspAla: 3.526 ± 0.064	0.346AspCys: 0.346 ± 0.016	1.977AspAsp: 1.977 ± 0.045	2.82AspGlu: 2.82 ± 0.054	2.899AspPhe: 2.899 ± 0.048	3.162AspGly: 3.162 ± 0.066	0.789AspHis: 0.789 ± 0.023	3.062AspIle: 3.062 ± 0.058	3.274AspLys: 3.274 ± 0.068	5.058AspLeu: 5.058 ± 0.064	1.035AspMet: 1.035 ± 0.025	2.32AspAsn: 2.32 ± 0.046	2.183AspPro: 2.183 ± 0.045	1.762AspGln: 1.762 ± 0.041	1.991AspArg: 1.991 ± 0.045	2.707AspSer: 2.707 ± 0.056	2.363AspThr: 2.363 ± 0.044	2.801AspVal: 2.801 ± 0.045	0.664AspTrp: 0.664 ± 0.021	2.147AspTyr: 2.147 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	4.993GluAla: 4.993 ± 0.082	0.303GluCys: 0.303 ± 0.015	2.699GluAsp: 2.699 ± 0.05	4.254GluGlu: 4.254 ± 0.089	2.563GluPhe: 2.563 ± 0.049	3.444GluGly: 3.444 ± 0.064	1.044GluHis: 1.044 ± 0.029	4.329GluIle: 4.329 ± 0.069	5.205GluLys: 5.205 ± 0.097	6.007GluLeu: 6.007 ± 0.103	1.627GluMet: 1.627 ± 0.035	3.791GluAsn: 3.791 ± 0.068	2.007GluPro: 2.007 ± 0.047	2.414GluGln: 2.414 ± 0.05	2.559GluArg: 2.559 ± 0.051	2.775GluSer: 2.775 ± 0.049	3.669GluThr: 3.669 ± 0.058	4.298GluVal: 4.298 ± 0.068	0.579GluTrp: 0.579 ± 0.022	1.96GluTyr: 1.96 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.499PheAla: 3.499 ± 0.056	0.461PheCys: 0.461 ± 0.02	2.586PheAsp: 2.586 ± 0.05	2.816PheGlu: 2.816 ± 0.051	2.54PhePhe: 2.54 ± 0.059	3.601PheGly: 3.601 ± 0.052	0.838PheHis: 0.838 ± 0.027	3.001PheIle: 3.001 ± 0.057	2.642PheLys: 2.642 ± 0.049	4.933PheLeu: 4.933 ± 0.085	1.03PheMet: 1.03 ± 0.028	2.698PheAsn: 2.698 ± 0.047	1.965PhePro: 1.965 ± 0.041	1.776PheGln: 1.776 ± 0.038	2.375PheArg: 2.375 ± 0.048	3.952PheSer: 3.952 ± 0.058	3.527PheThr: 3.527 ± 0.075	2.773PheVal: 2.773 ± 0.047	0.635PheTrp: 0.635 ± 0.025	2.024PheTyr: 2.024 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	5.026GlyAla: 5.026 ± 0.085	0.752GlyCys: 0.752 ± 0.035	2.914GlyAsp: 2.914 ± 0.053	3.458GlyGlu: 3.458 ± 0.057	3.693GlyPhe: 3.693 ± 0.053	5.296GlyGly: 5.296 ± 0.122	1.186GlyHis: 1.186 ± 0.036	5.013GlyIle: 5.013 ± 0.067	4.973GlyLys: 4.973 ± 0.072	6.483GlyLeu: 6.483 ± 0.079	1.65GlyMet: 1.65 ± 0.042	4.265GlyAsn: 4.265 ± 0.099	1.969GlyPro: 1.969 ± 0.046	2.63GlyGln: 2.63 ± 0.056	2.781GlyArg: 2.781 ± 0.051	4.881GlySer: 4.881 ± 0.117	5.409GlyThr: 5.409 ± 0.172	4.153GlyVal: 4.153 ± 0.064	0.871GlyTrp: 0.871 ± 0.027	2.872GlyTyr: 2.872 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.147HisAla: 1.147 ± 0.033	0.17HisCys: 0.17 ± 0.011	0.787HisAsp: 0.787 ± 0.026	1.01HisGlu: 1.01 ± 0.031	1.122HisPhe: 1.122 ± 0.03	1.098HisGly: 1.098 ± 0.029	0.487HisHis: 0.487 ± 0.026	1.097HisIle: 1.097 ± 0.035	0.952HisLys: 0.952 ± 0.027	2.012HisLeu: 2.012 ± 0.05	0.357HisMet: 0.357 ± 0.016	0.9HisAsn: 0.9 ± 0.025	0.969HisPro: 0.969 ± 0.029	0.705HisGln: 0.705 ± 0.023	0.822HisArg: 0.822 ± 0.025	0.982HisSer: 0.982 ± 0.029	1.051HisThr: 1.051 ± 0.028	0.979HisVal: 0.979 ± 0.031	0.237HisTrp: 0.237 ± 0.013	0.856HisTyr: 0.856 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.092IleAla: 5.092 ± 0.07	0.625IleCys: 0.625 ± 0.023	3.227IleAsp: 3.227 ± 0.051	3.554IleGlu: 3.554 ± 0.069	2.977IlePhe: 2.977 ± 0.055	4.542IleGly: 4.542 ± 0.067	1.023IleHis: 1.023 ± 0.03	4.002IleIle: 4.002 ± 0.069	3.881IleLys: 3.881 ± 0.066	5.763IleLeu: 5.763 ± 0.1	1.266IleMet: 1.266 ± 0.035	3.351IleAsn: 3.351 ± 0.059	3.033IlePro: 3.033 ± 0.05	2.192IleGln: 2.192 ± 0.043	2.9IleArg: 2.9 ± 0.053	4.744IleSer: 4.744 ± 0.071	4.417IleThr: 4.417 ± 0.075	3.646IleVal: 3.646 ± 0.062	0.627IleTrp: 0.627 ± 0.025	2.373IleTyr: 2.373 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	5.208LysAla: 5.208 ± 0.084	0.298LysCys: 0.298 ± 0.016	3.158LysAsp: 3.158 ± 0.061	4.51LysGlu: 4.51 ± 0.076	2.538LysPhe: 2.538 ± 0.042	3.986LysGly: 3.986 ± 0.058	1.139LysHis: 1.139 ± 0.032	4.222LysIle: 4.222 ± 0.07	4.776LysLys: 4.776 ± 0.093	6.266LysLeu: 6.266 ± 0.089	1.676LysMet: 1.676 ± 0.041	3.559LysAsn: 3.559 ± 0.061	3.043LysPro: 3.043 ± 0.051	2.528LysGln: 2.528 ± 0.048	2.515LysArg: 2.515 ± 0.048	3.254LysSer: 3.254 ± 0.058	4.029LysThr: 4.029 ± 0.056	4.48LysVal: 4.48 ± 0.069	0.663LysTrp: 0.663 ± 0.027	2.268LysTyr: 2.268 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	7.933LeuAla: 7.933 ± 0.1	0.725LeuCys: 0.725 ± 0.025	4.439LeuAsp: 4.439 ± 0.071	5.867LeuGlu: 5.867 ± 0.096	4.667LeuPhe: 4.667 ± 0.087	6.007LeuGly: 6.007 ± 0.076	1.907LeuHis: 1.907 ± 0.048	5.833LeuIle: 5.833 ± 0.09	6.971LeuLys: 6.971 ± 0.084	10.087LeuLeu: 10.087 ± 0.142	2.045LeuMet: 2.045 ± 0.045	5.56LeuAsn: 5.56 ± 0.078	4.731LeuPro: 4.731 ± 0.073	4.502LeuGln: 4.502 ± 0.074	4.084LeuArg: 4.084 ± 0.065	6.469LeuSer: 6.469 ± 0.079	6.211LeuThr: 6.211 ± 0.079	6.224LeuVal: 6.224 ± 0.084	0.892LeuTrp: 0.892 ± 0.029	3.212LeuTyr: 3.212 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	1.971MetAla: 1.971 ± 0.043	0.118MetCys: 0.118 ± 0.009	0.961MetAsp: 0.961 ± 0.031	1.346MetGlu: 1.346 ± 0.033	0.771MetPhe: 0.771 ± 0.025	1.374MetGly: 1.374 ± 0.036	0.484MetHis: 0.484 ± 0.021	1.174MetIle: 1.174 ± 0.032	1.806MetLys: 1.806 ± 0.042	2.263MetLeu: 2.263 ± 0.047	0.515MetMet: 0.515 ± 0.022	1.12MetAsn: 1.12 ± 0.03	1.165MetPro: 1.165 ± 0.032	1.051MetGln: 1.051 ± 0.029	1.007MetArg: 1.007 ± 0.03	1.076MetSer: 1.076 ± 0.03	1.002MetThr: 1.002 ± 0.023	1.482MetVal: 1.482 ± 0.033	0.143MetTrp: 0.143 ± 0.011	0.584MetTyr: 0.584 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	4.239AsnAla: 4.239 ± 0.078	0.481AsnCys: 0.481 ± 0.022	2.312AsnAsp: 2.312 ± 0.036	2.688AsnGlu: 2.688 ± 0.049	2.752AsnPhe: 2.752 ± 0.054	4.441AsnGly: 4.441 ± 0.104	0.927AsnHis: 0.927 ± 0.03	3.513AsnIle: 3.513 ± 0.066	2.985AsnLys: 2.985 ± 0.06	5.796AsnLeu: 5.796 ± 0.072	1.032AsnMet: 1.032 ± 0.029	3.188AsnAsn: 3.188 ± 0.073	3.168AsnPro: 3.168 ± 0.062	2.312AsnGln: 2.312 ± 0.047	2.429AsnArg: 2.429 ± 0.047	3.439AsnSer: 3.439 ± 0.073	3.405AsnThr: 3.405 ± 0.096	3.23AsnVal: 3.23 ± 0.06	0.837AsnTrp: 0.837 ± 0.03	2.367AsnTyr: 2.367 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	4.369ProAla: 4.369 ± 0.094	0.292ProCys: 0.292 ± 0.02	2.584ProAsp: 2.584 ± 0.047	3.973ProGlu: 3.973 ± 0.079	2.067ProPhe: 2.067 ± 0.042	3.137ProGly: 3.137 ± 0.061	0.724ProHis: 0.724 ± 0.023	2.208ProIle: 2.208 ± 0.037	2.357ProLys: 2.357 ± 0.05	3.499ProLeu: 3.499 ± 0.054	0.737ProMet: 0.737 ± 0.027	2.494ProAsn: 2.494 ± 0.061	1.315ProPro: 1.315 ± 0.041	1.52ProGln: 1.52 ± 0.035	1.248ProArg: 1.248 ± 0.033	2.229ProSer: 2.229 ± 0.05	2.416ProThr: 2.416 ± 0.061	3.915ProVal: 3.915 ± 0.073	0.397ProTrp: 0.397 ± 0.019	1.548ProTyr: 1.548 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.29GlnAla: 3.29 ± 0.054	0.185GlnCys: 0.185 ± 0.013	1.635GlnAsp: 1.635 ± 0.035	2.601GlnGlu: 2.601 ± 0.054	1.787GlnPhe: 1.787 ± 0.042	2.211GlnGly: 2.211 ± 0.041	0.826GlnHis: 0.826 ± 0.025	2.399GlnIle: 2.399 ± 0.044	2.787GlnLys: 2.787 ± 0.062	3.988GlnLeu: 3.988 ± 0.062	0.894GlnMet: 0.894 ± 0.028	2.37GlnAsn: 2.37 ± 0.047	1.867GlnPro: 1.867 ± 0.041	2.079GlnGln: 2.079 ± 0.044	1.595GlnArg: 1.595 ± 0.038	1.842GlnSer: 1.842 ± 0.04	2.592GlnThr: 2.592 ± 0.046	2.793GlnVal: 2.793 ± 0.049	0.425GlnTrp: 0.425 ± 0.02	1.398GlnTyr: 1.398 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.479ArgAla: 2.479 ± 0.048	0.249ArgCys: 0.249 ± 0.014	1.863ArgAsp: 1.863 ± 0.041	2.776ArgGlu: 2.776 ± 0.051	2.276ArgPhe: 2.276 ± 0.046	2.141ArgGly: 2.141 ± 0.046	0.842ArgHis: 0.842 ± 0.022	3.129ArgIle: 3.129 ± 0.049	3.109ArgLys: 3.109 ± 0.051	4.23ArgLeu: 4.23 ± 0.062	1.133ArgMet: 1.133 ± 0.031	2.62ArgAsn: 2.62 ± 0.049	1.57ArgPro: 1.57 ± 0.035	1.85ArgGln: 1.85 ± 0.04	1.803ArgArg: 1.803 ± 0.042	2.271ArgSer: 2.271 ± 0.042	2.375ArgThr: 2.375 ± 0.043	2.552ArgVal: 2.552 ± 0.046	0.498ArgTrp: 0.498 ± 0.018	1.758ArgTyr: 1.758 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.875SerAla: 4.875 ± 0.079	0.633SerCys: 0.633 ± 0.027	2.909SerAsp: 2.909 ± 0.046	3.458SerGlu: 3.458 ± 0.054	3.496SerPhe: 3.496 ± 0.059	5.841SerGly: 5.841 ± 0.144	1.021SerHis: 1.021 ± 0.025	3.781SerIle: 3.781 ± 0.06	3.328SerLys: 3.328 ± 0.056	6.075SerLeu: 6.075 ± 0.078	1.201SerMet: 1.201 ± 0.029	3.248SerAsn: 3.248 ± 0.083	2.697SerPro: 2.697 ± 0.064	2.084SerGln: 2.084 ± 0.043	2.614SerArg: 2.614 ± 0.045	4.107SerSer: 4.107 ± 0.094	3.755SerThr: 3.755 ± 0.108	4.181SerVal: 4.181 ± 0.068	0.767SerTrp: 0.767 ± 0.029	2.433SerTyr: 2.433 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	5.345ThrAla: 5.345 ± 0.132	0.474ThrCys: 0.474 ± 0.022	3.32ThrAsp: 3.32 ± 0.051	3.581ThrGlu: 3.581 ± 0.059	3.235ThrPhe: 3.235 ± 0.063	5.532ThrGly: 5.532 ± 0.142	1.042ThrHis: 1.042 ± 0.032	4.281ThrIle: 4.281 ± 0.079	2.867ThrLys: 2.867 ± 0.051	5.925ThrLeu: 5.925 ± 0.087	0.995ThrMet: 0.995 ± 0.029	3.223ThrAsn: 3.223 ± 0.094	3.057ThrPro: 3.057 ± 0.059	1.947ThrGln: 1.947 ± 0.046	2.249ThrArg: 2.249 ± 0.041	4.281ThrSer: 4.281 ± 0.124	4.088ThrThr: 4.088 ± 0.139	4.788ThrVal: 4.788 ± 0.111	0.786ThrTrp: 0.786 ± 0.032	2.65ThrTyr: 2.65 ± 0.064	0.0ThrXaa: 0.0 ± 0.0
Val	5.231ValAla: 5.231 ± 0.079	0.611ValCys: 0.611 ± 0.026	2.71ValAsp: 2.71 ± 0.056	3.589ValGlu: 3.589 ± 0.055	3.099ValPhe: 3.099 ± 0.052	3.865ValGly: 3.865 ± 0.064	1.039ValHis: 1.039 ± 0.031	4.134ValIle: 4.134 ± 0.075	4.439ValLys: 4.439 ± 0.064	6.325ValLeu: 6.325 ± 0.08	1.464ValMet: 1.464 ± 0.036	3.648ValAsn: 3.648 ± 0.077	2.856ValPro: 2.856 ± 0.052	2.475ValGln: 2.475 ± 0.047	2.705ValArg: 2.705 ± 0.047	4.59ValSer: 4.59 ± 0.068	4.496ValThr: 4.496 ± 0.12	4.474ValVal: 4.474 ± 0.073	0.694ValTrp: 0.694 ± 0.027	2.492ValTyr: 2.492 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.726TrpAla: 0.726 ± 0.025	0.093TrpCys: 0.093 ± 0.008	0.544TrpAsp: 0.544 ± 0.024	0.654TrpGlu: 0.654 ± 0.02	0.549TrpPhe: 0.549 ± 0.023	0.643TrpGly: 0.643 ± 0.024	0.244TrpHis: 0.244 ± 0.014	0.672TrpIle: 0.672 ± 0.028	0.685TrpLys: 0.685 ± 0.025	1.295TrpLeu: 1.295 ± 0.036	0.229TrpMet: 0.229 ± 0.014	0.685TrpAsn: 0.685 ± 0.027	0.36TrpPro: 0.36 ± 0.017	0.677TrpGln: 0.677 ± 0.025	0.472TrpArg: 0.472 ± 0.021	0.709TrpSer: 0.709 ± 0.032	0.647TrpThr: 0.647 ± 0.028	0.769TrpVal: 0.769 ± 0.027	0.133TrpTrp: 0.133 ± 0.011	0.435TrpTyr: 0.435 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.616TyrAla: 2.616 ± 0.046	0.353TyrCys: 0.353 ± 0.022	1.993TyrAsp: 1.993 ± 0.042	2.084TyrGlu: 2.084 ± 0.038	2.266TyrPhe: 2.266 ± 0.045	2.531TyrGly: 2.531 ± 0.056	0.79TyrHis: 0.79 ± 0.024	1.968TyrIle: 1.968 ± 0.044	2.316TyrLys: 2.316 ± 0.049	4.035TyrLeu: 4.035 ± 0.058	0.634TyrMet: 0.634 ± 0.021	2.183TyrAsn: 2.183 ± 0.044	1.543TyrPro: 1.543 ± 0.03	1.703TyrGln: 1.703 ± 0.035	1.988TyrArg: 1.988 ± 0.042	2.516TyrSer: 2.516 ± 0.055	2.393TyrThr: 2.393 ± 0.057	2.032TyrVal: 2.032 ± 0.035	0.477TyrTrp: 0.477 ± 0.025	1.814TyrTyr: 1.814 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3831 proteins (1363969 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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