Amino acid dipepetide frequency for Apis mellifera associated microvirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.292AlaAla: 21.292 ± 7.807
0.71AlaCys: 0.71 ± 0.589
7.097AlaAsp: 7.097 ± 1.984
5.678AlaGlu: 5.678 ± 2.009
4.968AlaPhe: 4.968 ± 1.572
6.388AlaGly: 6.388 ± 2.226
2.839AlaHis: 2.839 ± 0.665
4.258AlaIle: 4.258 ± 2.391
3.549AlaLys: 3.549 ± 2.128
9.936AlaLeu: 9.936 ± 3.346
1.419AlaMet: 1.419 ± 0.622
4.968AlaAsn: 4.968 ± 3.522
6.388AlaPro: 6.388 ± 2.849
7.097AlaGln: 7.097 ± 1.261
3.549AlaArg: 3.549 ± 1.324
3.549AlaSer: 3.549 ± 1.28
4.968AlaThr: 4.968 ± 2.019
7.807AlaVal: 7.807 ± 1.382
2.129AlaTrp: 2.129 ± 0.839
2.129AlaTyr: 2.129 ± 0.839
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.71CysAsp: 0.71 ± 0.773
0.0CysGlu: 0.0 ± 0.0
0.71CysPhe: 0.71 ± 0.589
1.419CysGly: 1.419 ± 1.178
0.0CysHis: 0.0 ± 0.0
1.419CysIle: 1.419 ± 1.178
0.0CysLys: 0.0 ± 0.0
0.71CysLeu: 0.71 ± 0.589
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.71CysPro: 0.71 ± 0.773
0.0CysGln: 0.0 ± 0.0
0.71CysArg: 0.71 ± 0.589
0.0CysSer: 0.0 ± 0.0
0.71CysThr: 0.71 ± 0.589
1.419CysVal: 1.419 ± 0.97
0.0CysTrp: 0.0 ± 0.0
0.71CysTyr: 0.71 ± 0.589
0.0CysXaa: 0.0 ± 0.0
Asp
4.968AspAla: 4.968 ± 2.585
0.0AspCys: 0.0 ± 0.0
0.71AspAsp: 0.71 ± 0.773
3.549AspGlu: 3.549 ± 1.731
2.839AspPhe: 2.839 ± 1.153
2.839AspGly: 2.839 ± 1.477
1.419AspHis: 1.419 ± 0.97
2.839AspIle: 2.839 ± 0.871
1.419AspLys: 1.419 ± 0.539
2.129AspLeu: 2.129 ± 0.871
1.419AspMet: 1.419 ± 0.834
2.129AspAsn: 2.129 ± 0.839
2.129AspPro: 2.129 ± 1.577
0.71AspGln: 0.71 ± 1.016
2.839AspArg: 2.839 ± 0.843
2.839AspSer: 2.839 ± 1.233
3.549AspThr: 3.549 ± 1.45
3.549AspVal: 3.549 ± 1.828
0.0AspTrp: 0.0 ± 0.0
4.968AspTyr: 4.968 ± 1.461
0.0AspXaa: 0.0 ± 0.0
Glu
8.517GluAla: 8.517 ± 3.252
0.71GluCys: 0.71 ± 0.773
1.419GluAsp: 1.419 ± 1.334
2.129GluGlu: 2.129 ± 1.318
0.71GluPhe: 0.71 ± 1.016
2.839GluGly: 2.839 ± 1.801
1.419GluHis: 1.419 ± 0.539
2.839GluIle: 2.839 ± 1.153
2.839GluLys: 2.839 ± 1.811
4.968GluLeu: 4.968 ± 2.725
0.71GluMet: 0.71 ± 0.52
2.839GluAsn: 2.839 ± 1.284
0.71GluPro: 0.71 ± 0.773
3.549GluGln: 3.549 ± 0.543
3.549GluArg: 3.549 ± 1.21
3.549GluSer: 3.549 ± 0.881
1.419GluThr: 1.419 ± 0.622
5.678GluVal: 5.678 ± 2.165
1.419GluTrp: 1.419 ± 0.539
2.839GluTyr: 2.839 ± 1.077
0.0GluXaa: 0.0 ± 0.0
Phe
4.968PheAla: 4.968 ± 2.038
0.0PheCys: 0.0 ± 0.0
3.549PheAsp: 3.549 ± 1.449
4.258PheGlu: 4.258 ± 2.058
4.968PhePhe: 4.968 ± 1.321
2.839PheGly: 2.839 ± 1.26
0.71PheHis: 0.71 ± 0.589
3.549PheIle: 3.549 ± 1.24
1.419PheLys: 1.419 ± 1.012
1.419PheLeu: 1.419 ± 0.97
1.419PheMet: 1.419 ± 0.552
2.129PheAsn: 2.129 ± 0.728
1.419PhePro: 1.419 ± 0.539
0.71PheGln: 0.71 ± 0.773
2.839PheArg: 2.839 ± 0.919
4.968PheSer: 4.968 ± 1.377
4.968PheThr: 4.968 ± 2.109
2.839PheVal: 2.839 ± 1.42
0.0PheTrp: 0.0 ± 0.0
1.419PheTyr: 1.419 ± 1.178
0.0PheXaa: 0.0 ± 0.0
Gly
7.807GlyAla: 7.807 ± 1.71
0.71GlyCys: 0.71 ± 0.589
3.549GlyAsp: 3.549 ± 0.543
4.968GlyGlu: 4.968 ± 2.096
2.129GlyPhe: 2.129 ± 0.97
6.388GlyGly: 6.388 ± 2.413
1.419GlyHis: 1.419 ± 0.813
1.419GlyIle: 1.419 ± 0.539
1.419GlyLys: 1.419 ± 0.622
7.807GlyLeu: 7.807 ± 2.359
0.71GlyMet: 0.71 ± 0.485
1.419GlyAsn: 1.419 ± 0.622
2.839GlyPro: 2.839 ± 1.176
4.258GlyGln: 4.258 ± 1.801
1.419GlyArg: 1.419 ± 0.841
5.678GlySer: 5.678 ± 1.559
5.678GlyThr: 5.678 ± 2.567
4.258GlyVal: 4.258 ± 1.208
0.71GlyTrp: 0.71 ± 0.589
4.258GlyTyr: 4.258 ± 2.189
0.0GlyXaa: 0.0 ± 0.0
His
2.839HisAla: 2.839 ± 0.919
0.71HisCys: 0.71 ± 0.589
2.839HisAsp: 2.839 ± 1.575
2.129HisGlu: 2.129 ± 1.318
2.129HisPhe: 2.129 ± 1.085
2.129HisGly: 2.129 ± 1.456
0.0HisHis: 0.0 ± 0.0
0.71HisIle: 0.71 ± 0.589
0.0HisLys: 0.0 ± 0.0
4.968HisLeu: 4.968 ± 1.626
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.129HisPro: 2.129 ± 1.275
0.71HisGln: 0.71 ± 0.68
0.0HisArg: 0.0 ± 0.0
0.71HisSer: 0.71 ± 0.485
0.0HisThr: 0.0 ± 0.0
0.71HisVal: 0.71 ± 0.589
0.71HisTrp: 0.71 ± 0.589
1.419HisTyr: 1.419 ± 0.539
0.0HisXaa: 0.0 ± 0.0
Ile
3.549IleAla: 3.549 ± 1.615
0.0IleCys: 0.0 ± 0.0
0.71IleAsp: 0.71 ± 0.485
2.129IleGlu: 2.129 ± 1.411
1.419IlePhe: 1.419 ± 0.622
2.839IleGly: 2.839 ± 1.668
1.419IleHis: 1.419 ± 0.539
0.71IleIle: 0.71 ± 0.785
2.129IleLys: 2.129 ± 0.773
4.968IleLeu: 4.968 ± 2.281
0.0IleMet: 0.0 ± 0.0
2.129IleAsn: 2.129 ± 0.884
0.71IlePro: 0.71 ± 0.485
0.0IleGln: 0.0 ± 0.0
4.258IleArg: 4.258 ± 2.118
1.419IleSer: 1.419 ± 0.539
4.968IleThr: 4.968 ± 1.093
2.129IleVal: 2.129 ± 1.678
0.0IleTrp: 0.0 ± 0.0
2.129IleTyr: 2.129 ± 1.456
0.0IleXaa: 0.0 ± 0.0
Lys
4.968LysAla: 4.968 ± 3.05
0.71LysCys: 0.71 ± 0.485
0.71LysAsp: 0.71 ± 0.68
1.419LysGlu: 1.419 ± 0.622
4.258LysPhe: 4.258 ± 2.159
2.839LysGly: 2.839 ± 1.244
0.71LysHis: 0.71 ± 1.016
1.419LysIle: 1.419 ± 0.841
2.839LysLys: 2.839 ± 1.357
2.129LysLeu: 2.129 ± 0.97
1.419LysMet: 1.419 ± 0.539
1.419LysAsn: 1.419 ± 0.841
0.71LysPro: 0.71 ± 0.485
2.839LysGln: 2.839 ± 1.682
4.258LysArg: 4.258 ± 1.575
2.129LysSer: 2.129 ± 0.871
1.419LysThr: 1.419 ± 0.622
3.549LysVal: 3.549 ± 0.881
0.71LysTrp: 0.71 ± 0.773
1.419LysTyr: 1.419 ± 1.178
0.0LysXaa: 0.0 ± 0.0
Leu
4.968LeuAla: 4.968 ± 0.915
0.71LeuCys: 0.71 ± 0.485
2.129LeuAsp: 2.129 ± 0.884
5.678LeuGlu: 5.678 ± 1.367
4.968LeuPhe: 4.968 ± 1.413
4.968LeuGly: 4.968 ± 1.576
1.419LeuHis: 1.419 ± 0.539
1.419LeuIle: 1.419 ± 0.774
4.258LeuLys: 4.258 ± 1.806
3.549LeuLeu: 3.549 ± 1.17
2.839LeuMet: 2.839 ± 1.146
8.517LeuAsn: 8.517 ± 1.469
7.807LeuPro: 7.807 ± 2.276
3.549LeuGln: 3.549 ± 1.716
8.517LeuArg: 8.517 ± 2.023
7.097LeuSer: 7.097 ± 2.901
4.968LeuThr: 4.968 ± 2.427
5.678LeuVal: 5.678 ± 1.48
1.419LeuTrp: 1.419 ± 1.178
1.419LeuTyr: 1.419 ± 0.813
0.0LeuXaa: 0.0 ± 0.0
Met
1.419MetAla: 1.419 ± 0.622
0.0MetCys: 0.0 ± 0.0
1.419MetAsp: 1.419 ± 0.622
0.0MetGlu: 0.0 ± 0.0
0.71MetPhe: 0.71 ± 0.589
0.71MetGly: 0.71 ± 0.485
0.0MetHis: 0.0 ± 0.0
0.71MetIle: 0.71 ± 0.485
3.549MetLys: 3.549 ± 1.068
2.129MetLeu: 2.129 ± 1.275
0.71MetMet: 0.71 ± 0.68
0.0MetAsn: 0.0 ± 0.0
0.71MetPro: 0.71 ± 0.485
2.839MetGln: 2.839 ± 1.86
2.129MetArg: 2.129 ± 0.583
2.129MetSer: 2.129 ± 1.013
1.419MetThr: 1.419 ± 0.539
0.0MetVal: 0.0 ± 0.0
0.71MetTrp: 0.71 ± 0.485
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.549AsnAla: 3.549 ± 1.453
1.419AsnCys: 1.419 ± 1.178
1.419AsnAsp: 1.419 ± 0.952
2.129AsnGlu: 2.129 ± 0.583
1.419AsnPhe: 1.419 ± 0.774
2.839AsnGly: 2.839 ± 1.146
0.71AsnHis: 0.71 ± 0.589
2.839AsnIle: 2.839 ± 1.86
2.129AsnLys: 2.129 ± 1.089
4.258AsnLeu: 4.258 ± 1.58
0.0AsnMet: 0.0 ± 0.0
4.258AsnAsn: 4.258 ± 3.374
4.258AsnPro: 4.258 ± 0.929
0.71AsnGln: 0.71 ± 0.485
0.71AsnArg: 0.71 ± 0.485
2.839AsnSer: 2.839 ± 1.334
2.839AsnThr: 2.839 ± 0.652
2.129AsnVal: 2.129 ± 0.773
0.71AsnTrp: 0.71 ± 0.485
1.419AsnTyr: 1.419 ± 0.905
0.0AsnXaa: 0.0 ± 0.0
Pro
6.388ProAla: 6.388 ± 2.269
0.71ProCys: 0.71 ± 0.589
4.258ProAsp: 4.258 ± 1.102
4.258ProGlu: 4.258 ± 1.41
2.839ProPhe: 2.839 ± 1.06
4.258ProGly: 4.258 ± 1.576
2.839ProHis: 2.839 ± 1.495
2.129ProIle: 2.129 ± 0.871
1.419ProLys: 1.419 ± 0.931
3.549ProLeu: 3.549 ± 1.227
0.71ProMet: 0.71 ± 0.485
1.419ProAsn: 1.419 ± 1.178
2.839ProPro: 2.839 ± 1.074
4.968ProGln: 4.968 ± 1.789
2.839ProArg: 2.839 ± 0.967
4.258ProSer: 4.258 ± 2.306
3.549ProThr: 3.549 ± 1.167
4.968ProVal: 4.968 ± 2.031
0.71ProTrp: 0.71 ± 0.485
1.419ProTyr: 1.419 ± 0.774
0.0ProXaa: 0.0 ± 0.0
Gln
6.388GlnAla: 6.388 ± 1.141
0.71GlnCys: 0.71 ± 0.589
0.71GlnAsp: 0.71 ± 0.68
2.839GlnGlu: 2.839 ± 0.652
2.129GlnPhe: 2.129 ± 0.871
2.129GlnGly: 2.129 ± 1.456
0.71GlnHis: 0.71 ± 0.485
0.71GlnIle: 0.71 ± 0.485
4.968GlnLys: 4.968 ± 1.93
6.388GlnLeu: 6.388 ± 1.463
1.419GlnMet: 1.419 ± 0.841
4.968GlnAsn: 4.968 ± 1.303
3.549GlnPro: 3.549 ± 1.763
2.129GlnGln: 2.129 ± 1.036
2.839GlnArg: 2.839 ± 1.244
1.419GlnSer: 1.419 ± 0.905
2.129GlnThr: 2.129 ± 0.97
2.129GlnVal: 2.129 ± 1.456
0.71GlnTrp: 0.71 ± 0.589
1.419GlnTyr: 1.419 ± 1.546
0.0GlnXaa: 0.0 ± 0.0
Arg
3.549ArgAla: 3.549 ± 1.24
0.71ArgCys: 0.71 ± 0.589
3.549ArgAsp: 3.549 ± 1.008
2.129ArgGlu: 2.129 ± 1.283
2.129ArgPhe: 2.129 ± 0.728
3.549ArgGly: 3.549 ± 1.827
2.129ArgHis: 2.129 ± 0.788
2.129ArgIle: 2.129 ± 0.871
2.129ArgLys: 2.129 ± 1.767
8.517ArgLeu: 8.517 ± 2.612
2.839ArgMet: 2.839 ± 1.206
0.71ArgAsn: 0.71 ± 1.016
5.678ArgPro: 5.678 ± 2.148
2.839ArgGln: 2.839 ± 0.784
3.549ArgArg: 3.549 ± 1.52
5.678ArgSer: 5.678 ± 1.382
2.129ArgThr: 2.129 ± 1.085
2.129ArgVal: 2.129 ± 0.97
0.0ArgTrp: 0.0 ± 0.0
3.549ArgTyr: 3.549 ± 0.893
0.0ArgXaa: 0.0 ± 0.0
Ser
10.646SerAla: 10.646 ± 2.209
0.0SerCys: 0.0 ± 0.0
1.419SerAsp: 1.419 ± 0.813
2.129SerGlu: 2.129 ± 1.283
4.258SerPhe: 4.258 ± 2.189
4.258SerGly: 4.258 ± 1.504
1.419SerHis: 1.419 ± 0.539
2.129SerIle: 2.129 ± 1.774
2.839SerLys: 2.839 ± 0.843
4.258SerLeu: 4.258 ± 1.096
2.839SerMet: 2.839 ± 1.842
1.419SerAsn: 1.419 ± 0.97
4.258SerPro: 4.258 ± 2.356
2.129SerGln: 2.129 ± 1.456
4.968SerArg: 4.968 ± 2.285
4.258SerSer: 4.258 ± 1.669
3.549SerThr: 3.549 ± 1.716
3.549SerVal: 3.549 ± 1.293
1.419SerTrp: 1.419 ± 1.57
0.71SerTyr: 0.71 ± 0.589
0.0SerXaa: 0.0 ± 0.0
Thr
6.388ThrAla: 6.388 ± 2.386
1.419ThrCys: 1.419 ± 0.905
1.419ThrAsp: 1.419 ± 0.949
3.549ThrGlu: 3.549 ± 1.24
3.549ThrPhe: 3.549 ± 1.716
8.517ThrGly: 8.517 ± 2.065
2.129ThrHis: 2.129 ± 0.728
2.129ThrIle: 2.129 ± 0.839
0.71ThrLys: 0.71 ± 0.485
7.097ThrLeu: 7.097 ± 1.256
1.419ThrMet: 1.419 ± 0.851
0.71ThrAsn: 0.71 ± 0.68
2.129ThrPro: 2.129 ± 1.089
4.258ThrGln: 4.258 ± 1.444
2.129ThrArg: 2.129 ± 0.839
2.839ThrSer: 2.839 ± 1.941
1.419ThrThr: 1.419 ± 0.97
1.419ThrVal: 1.419 ± 1.334
0.0ThrTrp: 0.0 ± 0.0
1.419ThrTyr: 1.419 ± 0.539
0.0ThrXaa: 0.0 ± 0.0
Val
4.968ValAla: 4.968 ± 0.779
0.0ValCys: 0.0 ± 0.0
4.968ValAsp: 4.968 ± 1.641
2.839ValGlu: 2.839 ± 1.594
2.129ValPhe: 2.129 ± 1.189
3.549ValGly: 3.549 ± 1.613
0.71ValHis: 0.71 ± 0.785
2.129ValIle: 2.129 ± 1.036
2.129ValLys: 2.129 ± 0.871
3.549ValLeu: 3.549 ± 0.962
0.0ValMet: 0.0 ± 0.0
2.129ValAsn: 2.129 ± 0.583
5.678ValPro: 5.678 ± 2.539
4.258ValGln: 4.258 ± 1.097
5.678ValArg: 5.678 ± 2.121
4.258ValSer: 4.258 ± 1.638
3.549ValThr: 3.549 ± 1.324
7.097ValVal: 7.097 ± 1.262
2.129ValTrp: 2.129 ± 1.523
3.549ValTyr: 3.549 ± 1.862
0.0ValXaa: 0.0 ± 0.0
Trp
1.419TrpAla: 1.419 ± 0.539
0.0TrpCys: 0.0 ± 0.0
0.71TrpAsp: 0.71 ± 0.485
0.71TrpGlu: 0.71 ± 0.773
1.419TrpPhe: 1.419 ± 0.539
0.71TrpGly: 0.71 ± 0.785
1.419TrpHis: 1.419 ± 0.813
0.0TrpIle: 0.0 ± 0.0
0.71TrpLys: 0.71 ± 0.589
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.839TrpPro: 2.839 ± 0.919
0.71TrpGln: 0.71 ± 0.589
0.71TrpArg: 0.71 ± 0.589
2.129TrpSer: 2.129 ± 0.788
0.0TrpThr: 0.0 ± 0.0
0.71TrpVal: 0.71 ± 0.485
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.129TyrAla: 2.129 ± 0.839
0.0TyrCys: 0.0 ± 0.0
3.549TyrAsp: 3.549 ± 1.166
2.129TyrGlu: 2.129 ± 0.728
0.71TyrPhe: 0.71 ± 0.485
2.839TyrGly: 2.839 ± 1.074
1.419TyrHis: 1.419 ± 1.178
2.129TyrIle: 2.129 ± 1.767
1.419TyrLys: 1.419 ± 0.97
3.549TyrLeu: 3.549 ± 1.728
0.71TyrMet: 0.71 ± 0.485
1.419TyrAsn: 1.419 ± 0.949
2.839TyrPro: 2.839 ± 1.128
2.129TyrGln: 2.129 ± 1.036
2.839TyrArg: 2.839 ± 0.919
0.71TyrSer: 0.71 ± 0.485
1.419TyrThr: 1.419 ± 0.539
3.549TyrVal: 3.549 ± 2.377
0.71TyrTrp: 0.71 ± 0.485
2.129TyrTyr: 2.129 ± 1.283
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1410 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski