Amino acid dipepetide frequency for Pothos latent virus (isolate Pigeonpea/India) (PoLV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.723AlaAla: 4.723 ± 2.836
2.699AlaCys: 2.699 ± 1.169
0.675AlaAsp: 0.675 ± 0.634
0.675AlaGlu: 0.675 ± 0.441
1.35AlaPhe: 1.35 ± 0.882
5.398AlaGly: 5.398 ± 2.388
2.024AlaHis: 2.024 ± 0.605
9.447AlaIle: 9.447 ± 2.876
2.024AlaLys: 2.024 ± 0.605
4.723AlaLeu: 4.723 ± 1.359
1.35AlaMet: 1.35 ± 0.625
4.723AlaAsn: 4.723 ± 1.021
5.398AlaPro: 5.398 ± 1.189
2.699AlaGln: 2.699 ± 1.971
1.35AlaArg: 1.35 ± 0.882
5.398AlaSer: 5.398 ± 1.742
6.073AlaThr: 6.073 ± 4.122
3.374AlaVal: 3.374 ± 1.06
0.0AlaTrp: 0.0 ± 0.0
2.699AlaTyr: 2.699 ± 0.763
0.0AlaXaa: 0.0 ± 0.0
Cys
2.024CysAla: 2.024 ± 0.605
0.675CysCys: 0.675 ± 0.441
0.675CysAsp: 0.675 ± 0.441
1.35CysGlu: 1.35 ± 0.436
0.675CysPhe: 0.675 ± 0.441
0.675CysGly: 0.675 ± 0.441
0.675CysHis: 0.675 ± 0.985
0.0CysIle: 0.0 ± 0.0
2.024CysLys: 2.024 ± 1.322
4.049CysLeu: 4.049 ± 1.942
0.675CysMet: 0.675 ± 0.441
0.0CysAsn: 0.0 ± 0.0
2.024CysPro: 2.024 ± 0.92
1.35CysGln: 1.35 ± 0.845
2.699CysArg: 2.699 ± 1.689
2.024CysSer: 2.024 ± 0.92
0.675CysThr: 0.675 ± 0.441
2.699CysVal: 2.699 ± 1.763
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.699AspAla: 2.699 ± 1.763
2.024AspCys: 2.024 ± 1.322
2.699AspAsp: 2.699 ± 1.763
2.024AspGlu: 2.024 ± 0.92
0.0AspPhe: 0.0 ± 0.0
4.723AspGly: 4.723 ± 1.93
0.0AspHis: 0.0 ± 0.0
0.675AspIle: 0.675 ± 0.441
1.35AspLys: 1.35 ± 0.436
4.049AspLeu: 4.049 ± 0.571
1.35AspMet: 1.35 ± 0.882
3.374AspAsn: 3.374 ± 0.699
2.699AspPro: 2.699 ± 1.763
2.024AspGln: 2.024 ± 0.995
4.049AspArg: 4.049 ± 1.572
1.35AspSer: 1.35 ± 1.262
0.0AspThr: 0.0 ± 0.0
5.398AspVal: 5.398 ± 0.353
0.675AspTrp: 0.675 ± 0.441
2.024AspTyr: 2.024 ± 1.273
0.0AspXaa: 0.0 ± 0.0
Glu
2.024GluAla: 2.024 ± 0.605
0.0GluCys: 0.0 ± 0.0
0.675GluAsp: 0.675 ± 0.441
2.699GluGlu: 2.699 ± 1.142
2.024GluPhe: 2.024 ± 0.809
1.35GluGly: 1.35 ± 0.625
0.675GluHis: 0.675 ± 0.441
3.374GluIle: 3.374 ± 1.015
4.049GluLys: 4.049 ± 2.645
4.723GluLeu: 4.723 ± 1.517
0.0GluMet: 0.0 ± 0.0
1.35GluAsn: 1.35 ± 0.845
2.024GluPro: 2.024 ± 0.995
2.024GluGln: 2.024 ± 0.926
6.073GluArg: 6.073 ± 3.223
4.723GluSer: 4.723 ± 0.59
2.699GluThr: 2.699 ± 1.019
5.398GluVal: 5.398 ± 1.846
2.024GluTrp: 2.024 ± 1.273
2.024GluTyr: 2.024 ± 0.809
0.0GluXaa: 0.0 ± 0.0
Phe
0.675PheAla: 0.675 ± 0.441
4.049PheCys: 4.049 ± 1.273
3.374PheAsp: 3.374 ± 1.399
2.024PheGlu: 2.024 ± 0.559
0.0PhePhe: 0.0 ± 0.0
2.699PheGly: 2.699 ± 0.871
0.675PheHis: 0.675 ± 0.985
0.675PheIle: 0.675 ± 0.634
2.699PheLys: 2.699 ± 1.142
0.0PheLeu: 0.0 ± 0.0
1.35PheMet: 1.35 ± 1.07
1.35PheAsn: 1.35 ± 0.92
2.024PhePro: 2.024 ± 0.926
0.0PheGln: 0.0 ± 0.0
2.699PheArg: 2.699 ± 0.411
2.024PheSer: 2.024 ± 0.559
2.699PheThr: 2.699 ± 1.344
4.723PheVal: 4.723 ± 1.612
0.675PheTrp: 0.675 ± 0.441
1.35PheTyr: 1.35 ± 0.625
0.0PheXaa: 0.0 ± 0.0
Gly
6.073GlyAla: 6.073 ± 1.691
1.35GlyCys: 1.35 ± 0.882
5.398GlyAsp: 5.398 ± 0.88
5.398GlyGlu: 5.398 ± 2.17
3.374GlyPhe: 3.374 ± 1.015
8.772GlyGly: 8.772 ± 3.11
2.699GlyHis: 2.699 ± 1.912
3.374GlyIle: 3.374 ± 0.835
2.699GlyLys: 2.699 ± 0.964
6.073GlyLeu: 6.073 ± 0.538
2.699GlyMet: 2.699 ± 1.142
3.374GlyAsn: 3.374 ± 0.699
2.024GlyPro: 2.024 ± 1.696
3.374GlyGln: 3.374 ± 1.886
5.398GlyArg: 5.398 ± 1.208
5.398GlySer: 5.398 ± 2.629
2.699GlyThr: 2.699 ± 0.871
7.422GlyVal: 7.422 ± 3.117
0.0GlyTrp: 0.0 ± 0.0
4.049GlyTyr: 4.049 ± 2.645
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.675HisCys: 0.675 ± 0.441
1.35HisAsp: 1.35 ± 0.882
0.675HisGlu: 0.675 ± 0.441
0.0HisPhe: 0.0 ± 0.0
2.699HisGly: 2.699 ± 1.893
0.675HisHis: 0.675 ± 0.985
0.675HisIle: 0.675 ± 0.719
1.35HisLys: 1.35 ± 0.625
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.675HisAsn: 0.675 ± 0.441
2.024HisPro: 2.024 ± 0.926
1.35HisGln: 1.35 ± 0.625
1.35HisArg: 1.35 ± 0.436
1.35HisSer: 1.35 ± 0.625
1.35HisThr: 1.35 ± 1.233
0.675HisVal: 0.675 ± 0.441
0.675HisTrp: 0.675 ± 0.634
0.675HisTyr: 0.675 ± 0.634
0.0HisXaa: 0.0 ± 0.0
Ile
5.398IleAla: 5.398 ± 2.388
0.0IleCys: 0.0 ± 0.0
3.374IleAsp: 3.374 ± 1.377
2.699IleGlu: 2.699 ± 1.142
1.35IlePhe: 1.35 ± 0.882
2.024IleGly: 2.024 ± 0.559
0.675IleHis: 0.675 ± 0.634
2.699IleIle: 2.699 ± 0.871
0.675IleLys: 0.675 ± 0.441
3.374IleLeu: 3.374 ± 1.003
0.675IleMet: 0.675 ± 0.456
2.024IleAsn: 2.024 ± 0.605
2.024IlePro: 2.024 ± 0.559
3.374IleGln: 3.374 ± 2.242
4.049IleArg: 4.049 ± 1.55
3.374IleSer: 3.374 ± 1.003
5.398IleThr: 5.398 ± 1.875
3.374IleVal: 3.374 ± 2.204
0.675IleTrp: 0.675 ± 0.634
1.35IleTyr: 1.35 ± 0.436
0.0IleXaa: 0.0 ± 0.0
Lys
4.723LysAla: 4.723 ± 1.438
0.0LysCys: 0.0 ± 0.0
3.374LysAsp: 3.374 ± 1.372
1.35LysGlu: 1.35 ± 0.625
3.374LysPhe: 3.374 ± 1.401
4.049LysGly: 4.049 ± 1.023
0.0LysHis: 0.0 ± 0.0
3.374LysIle: 3.374 ± 1.003
2.024LysLys: 2.024 ± 1.524
7.422LysLeu: 7.422 ± 1.037
2.024LysMet: 2.024 ± 0.809
1.35LysAsn: 1.35 ± 0.882
4.049LysPro: 4.049 ± 0.964
1.35LysGln: 1.35 ± 0.625
2.024LysArg: 2.024 ± 0.995
3.374LysSer: 3.374 ± 0.702
2.024LysThr: 2.024 ± 0.809
2.699LysVal: 2.699 ± 1.763
1.35LysTrp: 1.35 ± 0.625
0.675LysTyr: 0.675 ± 0.441
0.0LysXaa: 0.0 ± 0.0
Leu
9.447LeuAla: 9.447 ± 1.479
1.35LeuCys: 1.35 ± 0.845
3.374LeuAsp: 3.374 ± 1.531
4.049LeuGlu: 4.049 ± 1.942
2.699LeuPhe: 2.699 ± 2.537
4.723LeuGly: 4.723 ± 1.021
1.35LeuHis: 1.35 ± 0.436
2.699LeuIle: 2.699 ± 1.611
4.049LeuLys: 4.049 ± 2.645
6.748LeuLeu: 6.748 ± 1.162
2.024LeuMet: 2.024 ± 1.322
2.699LeuAsn: 2.699 ± 0.763
6.748LeuPro: 6.748 ± 2.191
6.073LeuGln: 6.073 ± 1.678
2.024LeuArg: 2.024 ± 1.322
10.121LeuSer: 10.121 ± 2.553
3.374LeuThr: 3.374 ± 1.531
9.447LeuVal: 9.447 ± 2.043
0.675LeuTrp: 0.675 ± 0.441
3.374LeuTyr: 3.374 ± 1.003
0.0LeuXaa: 0.0 ± 0.0
Met
2.024MetAla: 2.024 ± 0.995
1.35MetCys: 1.35 ± 0.436
0.0MetAsp: 0.0 ± 0.0
2.024MetGlu: 2.024 ± 1.009
0.675MetPhe: 0.675 ± 0.441
2.699MetGly: 2.699 ± 0.411
0.0MetHis: 0.0 ± 0.0
0.675MetIle: 0.675 ± 0.441
4.049MetLys: 4.049 ± 1.617
0.675MetLeu: 0.675 ± 0.634
0.675MetMet: 0.675 ± 0.719
2.024MetAsn: 2.024 ± 0.605
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.675MetArg: 0.675 ± 0.441
3.374MetSer: 3.374 ± 1.377
1.35MetThr: 1.35 ± 0.882
2.699MetVal: 2.699 ± 1.763
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.024AsnAla: 2.024 ± 0.995
0.675AsnCys: 0.675 ± 0.441
1.35AsnAsp: 1.35 ± 0.92
0.675AsnGlu: 0.675 ± 0.719
1.35AsnPhe: 1.35 ± 1.262
2.699AsnGly: 2.699 ± 1.979
0.675AsnHis: 0.675 ± 0.441
2.699AsnIle: 2.699 ± 0.411
0.0AsnLys: 0.0 ± 0.0
2.699AsnLeu: 2.699 ± 1.839
2.024AsnMet: 2.024 ± 1.069
3.374AsnAsn: 3.374 ± 2.237
2.699AsnPro: 2.699 ± 1.611
0.0AsnGln: 0.0 ± 0.0
0.675AsnArg: 0.675 ± 0.985
4.723AsnSer: 4.723 ± 0.963
2.699AsnThr: 2.699 ± 0.871
5.398AsnVal: 5.398 ± 1.929
2.024AsnTrp: 2.024 ± 0.605
1.35AsnTyr: 1.35 ± 0.436
0.0AsnXaa: 0.0 ± 0.0
Pro
5.398ProAla: 5.398 ± 2.189
1.35ProCys: 1.35 ± 0.882
3.374ProAsp: 3.374 ± 2.204
1.35ProGlu: 1.35 ± 0.882
1.35ProPhe: 1.35 ± 0.92
3.374ProGly: 3.374 ± 2.237
1.35ProHis: 1.35 ± 1.438
2.024ProIle: 2.024 ± 1.273
2.699ProLys: 2.699 ± 0.411
4.723ProLeu: 4.723 ± 1.575
0.675ProMet: 0.675 ± 0.634
2.699ProAsn: 2.699 ± 1.535
0.0ProPro: 0.0 ± 0.0
1.35ProGln: 1.35 ± 0.436
5.398ProArg: 5.398 ± 2.709
2.699ProSer: 2.699 ± 1.212
2.024ProThr: 2.024 ± 1.322
6.073ProVal: 6.073 ± 1.698
1.35ProTrp: 1.35 ± 1.268
0.675ProTyr: 0.675 ± 0.441
0.0ProXaa: 0.0 ± 0.0
Gln
2.024GlnAla: 2.024 ± 0.92
0.0GlnCys: 0.0 ± 0.0
0.675GlnAsp: 0.675 ± 0.634
0.0GlnGlu: 0.0 ± 0.0
3.374GlnPhe: 3.374 ± 1.913
4.049GlnGly: 4.049 ± 2.907
2.699GlnHis: 2.699 ± 1.763
1.35GlnIle: 1.35 ± 0.436
1.35GlnLys: 1.35 ± 0.625
2.699GlnLeu: 2.699 ± 0.411
0.0GlnMet: 0.0 ± 0.0
0.675GlnAsn: 0.675 ± 0.719
3.374GlnPro: 3.374 ± 1.534
2.024GlnGln: 2.024 ± 0.559
2.699GlnArg: 2.699 ± 0.964
3.374GlnSer: 3.374 ± 2.205
1.35GlnThr: 1.35 ± 1.262
2.699GlnVal: 2.699 ± 1.831
0.0GlnTrp: 0.0 ± 0.0
2.699GlnTyr: 2.699 ± 1.344
0.0GlnXaa: 0.0 ± 0.0
Arg
6.073ArgAla: 6.073 ± 1.035
0.675ArgCys: 0.675 ± 0.985
3.374ArgAsp: 3.374 ± 1.531
3.374ArgGlu: 3.374 ± 2.205
4.723ArgPhe: 4.723 ± 1.567
6.748ArgGly: 6.748 ± 1.43
0.0ArgHis: 0.0 ± 0.0
2.699ArgIle: 2.699 ± 0.871
4.723ArgLys: 4.723 ± 1.548
3.374ArgLeu: 3.374 ± 2.204
1.35ArgMet: 1.35 ± 0.625
0.675ArgAsn: 0.675 ± 0.634
4.049ArgPro: 4.049 ± 2.645
1.35ArgGln: 1.35 ± 0.845
4.723ArgArg: 4.723 ± 1.438
4.723ArgSer: 4.723 ± 1.353
0.0ArgThr: 0.0 ± 0.0
8.097ArgVal: 8.097 ± 1.116
1.35ArgTrp: 1.35 ± 0.882
3.374ArgTyr: 3.374 ± 2.204
0.0ArgXaa: 0.0 ± 0.0
Ser
1.35SerAla: 1.35 ± 0.436
2.024SerCys: 2.024 ± 1.322
3.374SerAsp: 3.374 ± 1.655
5.398SerGlu: 5.398 ± 1.822
3.374SerPhe: 3.374 ± 0.957
8.772SerGly: 8.772 ± 3.407
2.699SerHis: 2.699 ± 1.043
2.024SerIle: 2.024 ± 0.995
6.073SerLys: 6.073 ± 3.177
8.772SerLeu: 8.772 ± 2.041
2.699SerMet: 2.699 ± 1.763
2.024SerAsn: 2.024 ± 1.903
1.35SerPro: 1.35 ± 0.92
3.374SerGln: 3.374 ± 2.505
4.723SerArg: 4.723 ± 2.486
8.097SerSer: 8.097 ± 4.657
5.398SerThr: 5.398 ± 2.907
4.049SerVal: 4.049 ± 0.964
2.024SerTrp: 2.024 ± 0.92
0.675SerTyr: 0.675 ± 0.441
0.0SerXaa: 0.0 ± 0.0
Thr
4.049ThrAla: 4.049 ± 0.571
0.0ThrCys: 0.0 ± 0.0
0.675ThrAsp: 0.675 ± 0.634
4.049ThrGlu: 4.049 ± 1.99
1.35ThrPhe: 1.35 ± 0.436
2.699ThrGly: 2.699 ± 1.043
0.0ThrHis: 0.0 ± 0.0
4.723ThrIle: 4.723 ± 3.028
2.699ThrLys: 2.699 ± 0.911
7.422ThrLeu: 7.422 ± 3.684
1.35ThrMet: 1.35 ± 0.586
1.35ThrAsn: 1.35 ± 1.268
2.699ThrPro: 2.699 ± 1.251
0.675ThrGln: 0.675 ± 0.985
4.723ThrArg: 4.723 ± 1.331
4.049ThrSer: 4.049 ± 1.642
9.447ThrThr: 9.447 ± 4.933
3.374ThrVal: 3.374 ± 0.643
0.675ThrTrp: 0.675 ± 0.441
3.374ThrTyr: 3.374 ± 1.06
0.0ThrXaa: 0.0 ± 0.0
Val
4.049ValAla: 4.049 ± 1.852
3.374ValCys: 3.374 ± 1.71
4.723ValAsp: 4.723 ± 0.743
7.422ValGlu: 7.422 ± 1.628
3.374ValPhe: 3.374 ± 0.835
8.772ValGly: 8.772 ± 3.359
0.675ValHis: 0.675 ± 0.441
2.699ValIle: 2.699 ± 0.411
4.723ValLys: 4.723 ± 2.371
8.097ValLeu: 8.097 ± 1.752
3.374ValMet: 3.374 ± 0.643
2.699ValAsn: 2.699 ± 1.611
4.049ValPro: 4.049 ± 1.209
2.024ValGln: 2.024 ± 0.926
6.073ValArg: 6.073 ± 1.742
3.374ValSer: 3.374 ± 1.401
6.073ValThr: 6.073 ± 2.649
8.772ValVal: 8.772 ± 1.153
0.0ValTrp: 0.0 ± 0.0
4.049ValTyr: 4.049 ± 1.796
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.35TrpCys: 1.35 ± 0.436
0.0TrpAsp: 0.0 ± 0.0
1.35TrpGlu: 1.35 ± 0.882
0.675TrpPhe: 0.675 ± 0.441
0.675TrpGly: 0.675 ± 0.441
0.675TrpHis: 0.675 ± 0.441
1.35TrpIle: 1.35 ± 0.625
0.675TrpLys: 0.675 ± 0.719
2.699TrpLeu: 2.699 ± 0.763
0.0TrpMet: 0.0 ± 0.0
0.675TrpAsn: 0.675 ± 0.634
0.0TrpPro: 0.0 ± 0.0
0.675TrpGln: 0.675 ± 0.441
0.675TrpArg: 0.675 ± 0.719
0.0TrpSer: 0.0 ± 0.0
1.35TrpThr: 1.35 ± 0.436
0.675TrpVal: 0.675 ± 0.634
0.0TrpTrp: 0.0 ± 0.0
0.675TrpTyr: 0.675 ± 0.441
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.024TyrAla: 2.024 ± 0.809
1.35TyrCys: 1.35 ± 0.882
0.675TyrAsp: 0.675 ± 0.985
1.35TyrGlu: 1.35 ± 0.882
0.675TyrPhe: 0.675 ± 0.634
3.374TyrGly: 3.374 ± 0.643
0.0TyrHis: 0.0 ± 0.0
2.024TyrIle: 2.024 ± 0.92
0.675TyrLys: 0.675 ± 0.634
4.723TyrLeu: 4.723 ± 2.226
0.0TyrMet: 0.0 ± 0.0
2.699TyrAsn: 2.699 ± 0.964
0.675TyrPro: 0.675 ± 0.719
2.024TyrGln: 2.024 ± 0.605
3.374TyrArg: 3.374 ± 0.702
4.723TyrSer: 4.723 ± 1.93
2.699TyrThr: 2.699 ± 0.871
1.35TyrVal: 1.35 ± 0.436
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.675TyrXaa: 0.675 ± 0.441
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.675XaaGly: 0.675 ± 0.441
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1483 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski