Amino acid dipepetide frequency for Labeo rohita (Indian major carp) (Cyprinus rohita)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.704AlaAla: 5.704 ± 0.042	1.274AlaCys: 1.274 ± 0.012	3.348AlaAsp: 3.348 ± 0.037	4.578AlaGlu: 4.578 ± 0.023	2.443AlaPhe: 2.443 ± 0.02	4.01AlaGly: 4.01 ± 0.024	1.49AlaHis: 1.49 ± 0.011	2.849AlaIle: 2.849 ± 0.017	3.407AlaLys: 3.407 ± 0.024	6.47AlaLeu: 6.47 ± 0.031	1.5AlaMet: 1.5 ± 0.011	2.177AlaAsn: 2.177 ± 0.016	3.336AlaPro: 3.336 ± 0.025	2.975AlaGln: 2.975 ± 0.055	3.055AlaArg: 3.055 ± 0.017	5.345AlaSer: 5.345 ± 0.03	3.376AlaThr: 3.376 ± 0.019	5.108AlaVal: 5.108 ± 0.029	0.647AlaTrp: 0.647 ± 0.007	1.553AlaTyr: 1.553 ± 0.012	0.001AlaXaa: 0.001 ± 0.0
Cys	1.212CysAla: 1.212 ± 0.012	0.621CysCys: 0.621 ± 0.008	1.141CysAsp: 1.141 ± 0.014	1.323CysGlu: 1.323 ± 0.015	0.871CysPhe: 0.871 ± 0.009	1.532CysGly: 1.532 ± 0.017	0.607CysHis: 0.607 ± 0.007	0.955CysIle: 0.955 ± 0.011	1.167CysLys: 1.167 ± 0.01	2.046CysLeu: 2.046 ± 0.015	0.471CysMet: 0.471 ± 0.006	0.846CysAsn: 0.846 ± 0.01	1.234CysPro: 1.234 ± 0.016	0.984CysGln: 0.984 ± 0.01	1.32CysArg: 1.32 ± 0.025	2.06CysSer: 2.06 ± 0.02	1.198CysThr: 1.198 ± 0.011	1.515CysVal: 1.515 ± 0.014	0.292CysTrp: 0.292 ± 0.005	0.627CysTyr: 0.627 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	3.231AspAla: 3.231 ± 0.033	1.166AspCys: 1.166 ± 0.013	3.03AspAsp: 3.03 ± 0.019	3.804AspGlu: 3.804 ± 0.024	2.237AspPhe: 2.237 ± 0.024	3.575AspGly: 3.575 ± 0.024	1.197AspHis: 1.197 ± 0.01	3.024AspIle: 3.024 ± 0.023	2.791AspLys: 2.791 ± 0.014	5.15AspLeu: 5.15 ± 0.027	1.315AspMet: 1.315 ± 0.011	2.069AspAsn: 2.069 ± 0.029	2.778AspPro: 2.778 ± 0.017	2.008AspGln: 2.008 ± 0.013	2.713AspArg: 2.713 ± 0.021	4.473AspSer: 4.473 ± 0.023	2.805AspThr: 2.805 ± 0.016	3.715AspVal: 3.715 ± 0.071	0.693AspTrp: 0.693 ± 0.008	1.566AspTyr: 1.566 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	4.506GluAla: 4.506 ± 0.029	1.259GluCys: 1.259 ± 0.014	4.39GluAsp: 4.39 ± 0.025	7.199GluGlu: 7.199 ± 0.057	2.114GluPhe: 2.114 ± 0.015	3.92GluGly: 3.92 ± 0.055	1.56GluHis: 1.56 ± 0.017	3.253GluIle: 3.253 ± 0.024	4.985GluLys: 4.985 ± 0.041	6.066GluLeu: 6.066 ± 0.035	1.865GluMet: 1.865 ± 0.015	3.077GluAsn: 3.077 ± 0.023	2.779GluPro: 2.779 ± 0.02	3.159GluGln: 3.159 ± 0.025	4.439GluArg: 4.439 ± 0.034	4.676GluSer: 4.676 ± 0.033	3.776GluThr: 3.776 ± 0.025	4.336GluVal: 4.336 ± 0.021	0.747GluTrp: 0.747 ± 0.008	1.665GluTyr: 1.665 ± 0.015	0.001GluXaa: 0.001 ± 0.0
Phe	1.999PheAla: 1.999 ± 0.013	0.9PheCys: 0.9 ± 0.009	1.809PheAsp: 1.809 ± 0.013	2.005PheGlu: 2.005 ± 0.023	1.548PhePhe: 1.548 ± 0.014	2.244PheGly: 2.244 ± 0.018	0.993PheHis: 0.993 ± 0.009	2.014PheIle: 2.014 ± 0.016	1.911PheLys: 1.911 ± 0.013	3.705PheLeu: 3.705 ± 0.02	0.842PheMet: 0.842 ± 0.008	1.597PheAsn: 1.597 ± 0.019	1.773PhePro: 1.773 ± 0.013	1.698PheGln: 1.698 ± 0.023	1.857PheArg: 1.857 ± 0.011	3.406PheSer: 3.406 ± 0.019	2.326PheThr: 2.326 ± 0.014	2.232PheVal: 2.232 ± 0.015	0.471PheTrp: 0.471 ± 0.007	1.286PheTyr: 1.286 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	3.759GlyAla: 3.759 ± 0.059	1.206GlyCys: 1.206 ± 0.012	3.102GlyAsp: 3.102 ± 0.021	3.777GlyGlu: 3.777 ± 0.025	2.413GlyPhe: 2.413 ± 0.018	4.32GlyGly: 4.32 ± 0.03	1.55GlyHis: 1.55 ± 0.013	2.642GlyIle: 2.642 ± 0.016	3.497GlyLys: 3.497 ± 0.022	5.277GlyLeu: 5.277 ± 0.026	1.37GlyMet: 1.37 ± 0.01	2.47GlyAsn: 2.47 ± 0.018	3.061GlyPro: 3.061 ± 0.044	2.624GlyGln: 2.624 ± 0.019	3.57GlyArg: 3.57 ± 0.023	5.315GlySer: 5.315 ± 0.03	3.363GlyThr: 3.363 ± 0.023	3.917GlyVal: 3.917 ± 0.023	0.733GlyTrp: 0.733 ± 0.008	1.814GlyTyr: 1.814 ± 0.013	0.001GlyXaa: 0.001 ± 0.0
His	1.344HisAla: 1.344 ± 0.01	0.701HisCys: 0.701 ± 0.009	1.061HisAsp: 1.061 ± 0.009	1.305HisGlu: 1.305 ± 0.011	1.075HisPhe: 1.075 ± 0.011	1.467HisGly: 1.467 ± 0.013	0.879HisHis: 0.879 ± 0.011	1.314HisIle: 1.314 ± 0.012	1.297HisLys: 1.297 ± 0.009	2.607HisLeu: 2.607 ± 0.016	0.622HisMet: 0.622 ± 0.007	1.132HisAsn: 1.132 ± 0.026	1.448HisPro: 1.448 ± 0.011	1.183HisGln: 1.183 ± 0.01	1.551HisArg: 1.551 ± 0.012	2.238HisSer: 2.238 ± 0.015	1.444HisThr: 1.444 ± 0.011	1.523HisVal: 1.523 ± 0.011	0.333HisTrp: 0.333 ± 0.005	0.85HisTyr: 0.85 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	2.72IleAla: 2.72 ± 0.017	1.141IleCys: 1.141 ± 0.011	2.244IleAsp: 2.244 ± 0.015	2.641IleGlu: 2.641 ± 0.02	1.814IlePhe: 1.814 ± 0.015	2.34IleGly: 2.34 ± 0.014	1.242IleHis: 1.242 ± 0.01	2.652IleIle: 2.652 ± 0.019	2.824IleLys: 2.824 ± 0.02	4.459IleLeu: 4.459 ± 0.022	1.156IleMet: 1.156 ± 0.01	2.126IleAsn: 2.126 ± 0.021	2.586IlePro: 2.586 ± 0.016	2.317IleGln: 2.317 ± 0.018	2.517IleArg: 2.517 ± 0.015	4.051IleSer: 4.051 ± 0.022	3.144IleThr: 3.144 ± 0.023	2.81IleVal: 2.81 ± 0.018	0.509IleTrp: 0.509 ± 0.006	1.513IleTyr: 1.513 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.802LysAla: 3.802 ± 0.021	1.095LysCys: 1.095 ± 0.009	3.411LysAsp: 3.411 ± 0.018	4.886LysGlu: 4.886 ± 0.038	1.662LysPhe: 1.662 ± 0.015	3.224LysGly: 3.224 ± 0.024	1.52LysHis: 1.52 ± 0.013	2.774LysIle: 2.774 ± 0.016	4.517LysLys: 4.517 ± 0.031	5.027LysLeu: 5.027 ± 0.027	1.573LysMet: 1.573 ± 0.012	2.518LysAsn: 2.518 ± 0.017	2.96LysPro: 2.96 ± 0.023	2.674LysGln: 2.674 ± 0.021	3.583LysArg: 3.583 ± 0.021	3.956LysSer: 3.956 ± 0.024	3.464LysThr: 3.464 ± 0.018	3.558LysVal: 3.558 ± 0.021	0.653LysTrp: 0.653 ± 0.007	1.57LysTyr: 1.57 ± 0.012	0.001LysXaa: 0.001 ± 0.0
Leu	5.751LeuAla: 5.751 ± 0.027	2.055LeuCys: 2.055 ± 0.015	4.79LeuAsp: 4.79 ± 0.021	6.38LeuGlu: 6.38 ± 0.041	3.279LeuPhe: 3.279 ± 0.02	4.804LeuGly: 4.804 ± 0.021	2.561LeuHis: 2.561 ± 0.014	4.004LeuIle: 4.004 ± 0.022	5.917LeuLys: 5.917 ± 0.028	9.484LeuLeu: 9.484 ± 0.05	2.169LeuMet: 2.169 ± 0.014	3.851LeuAsn: 3.851 ± 0.021	5.081LeuPro: 5.081 ± 0.028	5.346LeuGln: 5.346 ± 0.033	5.54LeuArg: 5.54 ± 0.035	8.165LeuSer: 8.165 ± 0.034	5.299LeuThr: 5.299 ± 0.025	5.315LeuVal: 5.315 ± 0.029	1.042LeuTrp: 1.042 ± 0.009	2.57LeuTyr: 2.57 ± 0.016	0.001LeuXaa: 0.001 ± 0.0
Met	1.776MetAla: 1.776 ± 0.013	0.475MetCys: 0.475 ± 0.006	1.449MetAsp: 1.449 ± 0.01	2.021MetGlu: 2.021 ± 0.016	0.885MetPhe: 0.885 ± 0.01	1.34MetGly: 1.34 ± 0.011	0.481MetHis: 0.481 ± 0.006	0.991MetIle: 0.991 ± 0.009	1.597MetLys: 1.597 ± 0.013	2.055MetLeu: 2.055 ± 0.013	0.723MetMet: 0.723 ± 0.008	0.998MetAsn: 0.998 ± 0.008	1.106MetPro: 1.106 ± 0.012	0.997MetGln: 0.997 ± 0.008	1.268MetArg: 1.268 ± 0.011	1.835MetSer: 1.835 ± 0.013	1.321MetThr: 1.321 ± 0.01	1.509MetVal: 1.509 ± 0.013	0.268MetTrp: 0.268 ± 0.005	0.644MetTyr: 0.644 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.346AsnAla: 2.346 ± 0.017	0.922AsnCys: 0.922 ± 0.012	1.825AsnAsp: 1.825 ± 0.012	2.413AsnGlu: 2.413 ± 0.023	1.499AsnPhe: 1.499 ± 0.014	2.818AsnGly: 2.818 ± 0.022	0.994AsnHis: 0.994 ± 0.011	2.421AsnIle: 2.421 ± 0.016	2.348AsnLys: 2.348 ± 0.016	3.638AsnLeu: 3.638 ± 0.019	1.071AsnMet: 1.071 ± 0.01	2.039AsnAsn: 2.039 ± 0.041	2.206AsnPro: 2.206 ± 0.014	1.74AsnGln: 1.74 ± 0.014	2.34AsnArg: 2.34 ± 0.07	3.294AsnSer: 3.294 ± 0.017	2.425AsnThr: 2.425 ± 0.018	2.526AsnVal: 2.526 ± 0.017	0.483AsnTrp: 0.483 ± 0.008	1.326AsnTyr: 1.326 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	3.893ProAla: 3.893 ± 0.027	1.047ProCys: 1.047 ± 0.013	2.927ProAsp: 2.927 ± 0.022	3.824ProGlu: 3.824 ± 0.023	1.787ProPhe: 1.787 ± 0.013	3.622ProGly: 3.622 ± 0.052	1.376ProHis: 1.376 ± 0.013	1.905ProIle: 1.905 ± 0.013	2.659ProLys: 2.659 ± 0.022	4.533ProLeu: 4.533 ± 0.022	0.989ProMet: 0.989 ± 0.01	1.918ProAsn: 1.918 ± 0.014	4.547ProPro: 4.547 ± 0.044	2.534ProGln: 2.534 ± 0.018	2.558ProArg: 2.558 ± 0.017	5.102ProSer: 5.102 ± 0.033	2.938ProThr: 2.938 ± 0.021	3.976ProVal: 3.976 ± 0.026	0.566ProTrp: 0.566 ± 0.007	1.424ProTyr: 1.424 ± 0.01	0.0ProXaa: 0.0 ± 0.0
Gln	3.035GlnAla: 3.035 ± 0.019	1.022GlnCys: 1.022 ± 0.014	2.368GlnAsp: 2.368 ± 0.014	3.545GlnGlu: 3.545 ± 0.054	1.384GlnPhe: 1.384 ± 0.011	2.507GlnGly: 2.507 ± 0.019	1.296GlnHis: 1.296 ± 0.009	2.033GlnIle: 2.033 ± 0.013	2.837GlnLys: 2.837 ± 0.024	4.209GlnLeu: 4.209 ± 0.027	1.199GlnMet: 1.199 ± 0.012	2.013GlnAsn: 2.013 ± 0.015	2.351GlnPro: 2.351 ± 0.021	2.811GlnGln: 2.811 ± 0.028	3.01GlnArg: 3.01 ± 0.02	3.529GlnSer: 3.529 ± 0.026	2.823GlnThr: 2.823 ± 0.053	2.668GlnVal: 2.668 ± 0.016	0.571GlnTrp: 0.571 ± 0.006	1.272GlnTyr: 1.272 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.442ArgAla: 3.442 ± 0.025	1.186ArgCys: 1.186 ± 0.012	2.969ArgAsp: 2.969 ± 0.016	3.96ArgGlu: 3.96 ± 0.031	2.007ArgPhe: 2.007 ± 0.013	3.245ArgGly: 3.245 ± 0.026	1.532ArgHis: 1.532 ± 0.014	2.477ArgIle: 2.477 ± 0.015	3.629ArgLys: 3.629 ± 0.019	5.193ArgLeu: 5.193 ± 0.023	1.309ArgMet: 1.309 ± 0.01	2.326ArgAsn: 2.326 ± 0.033	2.789ArgPro: 2.789 ± 0.016	2.648ArgGln: 2.648 ± 0.023	4.327ArgArg: 4.327 ± 0.035	4.448ArgSer: 4.448 ± 0.036	2.971ArgThr: 2.971 ± 0.026	3.431ArgVal: 3.431 ± 0.02	0.737ArgTrp: 0.737 ± 0.008	1.641ArgTyr: 1.641 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	5.647SerAla: 5.647 ± 0.036	1.857SerCys: 1.857 ± 0.018	4.584SerAsp: 4.584 ± 0.031	5.238SerGlu: 5.238 ± 0.028	3.023SerPhe: 3.023 ± 0.017	5.413SerGly: 5.413 ± 0.034	2.096SerHis: 2.096 ± 0.017	3.538SerIle: 3.538 ± 0.03	4.11SerLys: 4.11 ± 0.02	7.89SerLeu: 7.89 ± 0.033	1.764SerMet: 1.764 ± 0.01	2.985SerAsn: 2.985 ± 0.017	5.403SerPro: 5.403 ± 0.039	3.712SerGln: 3.712 ± 0.025	4.305SerArg: 4.305 ± 0.024	9.314SerSer: 9.314 ± 0.052	5.035SerThr: 5.035 ± 0.036	5.766SerVal: 5.766 ± 0.033	0.976SerTrp: 0.976 ± 0.009	2.156SerTyr: 2.156 ± 0.017	0.001SerXaa: 0.001 ± 0.0
Thr	4.194ThrAla: 4.194 ± 0.025	1.353ThrCys: 1.353 ± 0.019	3.32ThrAsp: 3.32 ± 0.024	4.214ThrGlu: 4.214 ± 0.035	2.122ThrPhe: 2.122 ± 0.015	3.632ThrGly: 3.632 ± 0.02	1.355ThrHis: 1.355 ± 0.01	2.58ThrIle: 2.58 ± 0.021	2.763ThrLys: 2.763 ± 0.017	5.43ThrLeu: 5.43 ± 0.024	1.175ThrMet: 1.175 ± 0.01	2.083ThrAsn: 2.083 ± 0.017	3.501ThrPro: 3.501 ± 0.025	2.467ThrGln: 2.467 ± 0.052	2.554ThrArg: 2.554 ± 0.016	4.826ThrSer: 4.826 ± 0.024	3.679ThrThr: 3.679 ± 0.092	4.401ThrVal: 4.401 ± 0.024	0.67ThrTrp: 0.67 ± 0.008	1.598ThrTyr: 1.598 ± 0.022	0.001ThrXaa: 0.001 ± 0.0
Val	4.089ValAla: 4.089 ± 0.027	1.715ValCys: 1.715 ± 0.015	3.4ValAsp: 3.4 ± 0.049	4.244ValGlu: 4.244 ± 0.024	2.732ValPhe: 2.732 ± 0.017	3.4ValGly: 3.4 ± 0.025	1.565ValHis: 1.565 ± 0.011	3.294ValIle: 3.294 ± 0.019	3.855ValLys: 3.855 ± 0.02	6.4ValLeu: 6.4 ± 0.032	1.607ValMet: 1.607 ± 0.01	2.612ValAsn: 2.612 ± 0.019	3.395ValPro: 3.395 ± 0.023	2.865ValGln: 2.865 ± 0.017	3.33ValArg: 3.33 ± 0.019	5.409ValSer: 5.409 ± 0.024	4.127ValThr: 4.127 ± 0.025	4.852ValVal: 4.852 ± 0.079	0.792ValTrp: 0.792 ± 0.008	1.876ValTyr: 1.876 ± 0.013	0.001ValXaa: 0.001 ± 0.0
Trp	0.712TrpAla: 0.712 ± 0.008	0.247TrpCys: 0.247 ± 0.004	0.665TrpAsp: 0.665 ± 0.008	0.738TrpGlu: 0.738 ± 0.008	0.482TrpPhe: 0.482 ± 0.007	0.637TrpGly: 0.637 ± 0.009	0.269TrpHis: 0.269 ± 0.004	0.603TrpIle: 0.603 ± 0.007	0.776TrpLys: 0.776 ± 0.008	1.126TrpLeu: 1.126 ± 0.01	0.33TrpMet: 0.33 ± 0.005	0.528TrpAsn: 0.528 ± 0.006	0.471TrpPro: 0.471 ± 0.006	0.495TrpGln: 0.495 ± 0.007	0.748TrpArg: 0.748 ± 0.007	0.946TrpSer: 0.946 ± 0.009	0.744TrpThr: 0.744 ± 0.009	0.717TrpVal: 0.717 ± 0.007	0.184TrpTrp: 0.184 ± 0.004	0.354TrpTyr: 0.354 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.485TyrAla: 1.485 ± 0.012	0.779TyrCys: 0.779 ± 0.024	1.509TyrAsp: 1.509 ± 0.02	1.678TyrGlu: 1.678 ± 0.014	1.24TyrPhe: 1.24 ± 0.023	1.726TyrGly: 1.726 ± 0.013	0.811TyrHis: 0.811 ± 0.009	1.485TyrIle: 1.485 ± 0.012	1.541TyrLys: 1.541 ± 0.014	2.64TyrLeu: 2.64 ± 0.021	0.687TyrMet: 0.687 ± 0.008	1.308TyrAsn: 1.308 ± 0.018	1.318TyrPro: 1.318 ± 0.013	1.246TyrGln: 1.246 ± 0.012	1.681TyrArg: 1.681 ± 0.014	2.423TyrSer: 2.423 ± 0.032	1.659TyrThr: 1.659 ± 0.015	1.685TyrVal: 1.685 ± 0.014	0.406TyrTrp: 0.406 ± 0.007	1.13TyrTyr: 1.13 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.004XaaXaa: 0.004 ± 0.002

Statistics based on 32379 proteins (16615359 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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