Amino acid dipepetide frequency for Acholeplasma phage L2 (Bacteriophage L2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.667AlaAla: 3.667 ± 1.007
0.0AlaCys: 0.0 ± 0.0
1.528AlaAsp: 1.528 ± 0.779
2.139AlaGlu: 2.139 ± 0.678
2.445AlaPhe: 2.445 ± 1.506
2.751AlaGly: 2.751 ± 0.873
1.834AlaHis: 1.834 ± 1.075
3.362AlaIle: 3.362 ± 0.846
2.445AlaLys: 2.445 ± 1.184
6.418AlaLeu: 6.418 ± 1.055
0.917AlaMet: 0.917 ± 0.74
3.056AlaAsn: 3.056 ± 0.966
1.528AlaPro: 1.528 ± 0.422
1.834AlaGln: 1.834 ± 0.856
0.917AlaArg: 0.917 ± 0.418
5.501AlaSer: 5.501 ± 0.872
2.445AlaThr: 2.445 ± 0.886
5.501AlaVal: 5.501 ± 1.831
0.306AlaTrp: 0.306 ± 0.226
4.279AlaTyr: 4.279 ± 1.278
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.306CysIle: 0.306 ± 0.347
0.0CysLys: 0.0 ± 0.0
0.917CysLeu: 0.917 ± 0.799
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.306CysSer: 0.306 ± 0.273
0.306CysThr: 0.306 ± 0.302
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.584AspAla: 4.584 ± 1.03
0.0AspCys: 0.0 ± 0.0
2.751AspAsp: 2.751 ± 1.095
2.751AspGlu: 2.751 ± 0.722
3.973AspPhe: 3.973 ± 0.895
6.724AspGly: 6.724 ± 1.607
0.306AspHis: 0.306 ± 0.323
6.112AspIle: 6.112 ± 1.242
3.056AspLys: 3.056 ± 1.271
4.279AspLeu: 4.279 ± 0.942
0.917AspMet: 0.917 ± 0.574
2.139AspAsn: 2.139 ± 0.846
2.139AspPro: 2.139 ± 0.68
1.834AspGln: 1.834 ± 0.571
1.528AspArg: 1.528 ± 0.399
4.279AspSer: 4.279 ± 0.887
4.584AspThr: 4.584 ± 0.848
2.445AspVal: 2.445 ± 0.639
0.917AspTrp: 0.917 ± 0.521
2.751AspTyr: 2.751 ± 0.655
0.0AspXaa: 0.0 ± 0.0
Glu
2.751GluAla: 2.751 ± 1.272
0.0GluCys: 0.0 ± 0.0
2.445GluAsp: 2.445 ± 0.719
2.139GluGlu: 2.139 ± 0.977
3.056GluPhe: 3.056 ± 0.778
0.917GluGly: 0.917 ± 0.424
0.917GluHis: 0.917 ± 0.685
4.89GluIle: 4.89 ± 1.359
2.751GluLys: 2.751 ± 1.08
5.501GluLeu: 5.501 ± 1.635
0.0GluMet: 0.0 ± 0.0
5.501GluAsn: 5.501 ± 0.994
1.834GluPro: 1.834 ± 1.254
3.362GluGln: 3.362 ± 1.269
3.973GluArg: 3.973 ± 1.497
3.362GluSer: 3.362 ± 0.726
3.667GluThr: 3.667 ± 0.726
2.445GluVal: 2.445 ± 0.734
0.917GluTrp: 0.917 ± 0.552
2.139GluTyr: 2.139 ± 0.752
0.0GluXaa: 0.0 ± 0.0
Phe
1.528PheAla: 1.528 ± 0.7
0.0PheCys: 0.0 ± 0.0
3.056PheAsp: 3.056 ± 0.725
2.445PheGlu: 2.445 ± 0.554
3.362PhePhe: 3.362 ± 1.391
1.834PheGly: 1.834 ± 1.065
1.222PheHis: 1.222 ± 0.673
5.807PheIle: 5.807 ± 1.849
3.362PheLys: 3.362 ± 1.104
2.445PheLeu: 2.445 ± 0.878
0.917PheMet: 0.917 ± 0.392
4.89PheAsn: 4.89 ± 1.243
0.611PhePro: 0.611 ± 0.286
0.306PheGln: 0.306 ± 0.273
3.362PheArg: 3.362 ± 0.705
3.667PheSer: 3.667 ± 0.958
3.667PheThr: 3.667 ± 0.97
3.056PheVal: 3.056 ± 1.164
0.306PheTrp: 0.306 ± 0.353
3.056PheTyr: 3.056 ± 0.944
0.0PheXaa: 0.0 ± 0.0
Gly
2.139GlyAla: 2.139 ± 0.846
0.306GlyCys: 0.306 ± 0.273
1.834GlyAsp: 1.834 ± 0.772
2.445GlyGlu: 2.445 ± 0.841
3.056GlyPhe: 3.056 ± 0.957
2.139GlyGly: 2.139 ± 1.021
0.306GlyHis: 0.306 ± 0.273
5.501GlyIle: 5.501 ± 1.722
3.056GlyLys: 3.056 ± 1.318
7.641GlyLeu: 7.641 ± 1.24
1.528GlyMet: 1.528 ± 0.95
5.196GlyAsn: 5.196 ± 1.235
2.139GlyPro: 2.139 ± 0.7
2.751GlyGln: 2.751 ± 1.536
0.917GlyArg: 0.917 ± 0.446
3.362GlySer: 3.362 ± 0.88
1.834GlyThr: 1.834 ± 0.844
3.667GlyVal: 3.667 ± 1.142
0.0GlyTrp: 0.0 ± 0.0
4.89GlyTyr: 4.89 ± 1.756
0.0GlyXaa: 0.0 ± 0.0
His
0.917HisAla: 0.917 ± 0.74
0.0HisCys: 0.0 ± 0.0
0.917HisAsp: 0.917 ± 0.481
0.611HisGlu: 0.611 ± 0.437
0.0HisPhe: 0.0 ± 0.0
0.611HisGly: 0.611 ± 0.416
0.306HisHis: 0.306 ± 0.273
0.611HisIle: 0.611 ± 0.286
1.222HisLys: 1.222 ± 0.577
2.445HisLeu: 2.445 ± 1.324
0.0HisMet: 0.0 ± 0.0
0.611HisAsn: 0.611 ± 0.646
0.0HisPro: 0.0 ± 0.0
1.222HisGln: 1.222 ± 0.657
0.917HisArg: 0.917 ± 0.757
0.611HisSer: 0.611 ± 0.342
1.528HisThr: 1.528 ± 0.669
1.222HisVal: 1.222 ± 0.662
0.0HisTrp: 0.0 ± 0.0
1.834HisTyr: 1.834 ± 0.797
0.0HisXaa: 0.0 ± 0.0
Ile
5.807IleAla: 5.807 ± 1.215
0.611IleCys: 0.611 ± 0.458
7.335IleAsp: 7.335 ± 1.348
5.196IleGlu: 5.196 ± 1.544
3.973IlePhe: 3.973 ± 1.22
3.667IleGly: 3.667 ± 0.571
0.917IleHis: 0.917 ± 0.425
7.335IleIle: 7.335 ± 1.317
10.086IleLys: 10.086 ± 2.632
8.252IleLeu: 8.252 ± 1.45
1.222IleMet: 1.222 ± 0.681
6.418IleAsn: 6.418 ± 1.128
2.751IlePro: 2.751 ± 0.917
2.751IleGln: 2.751 ± 1.1
4.279IleArg: 4.279 ± 1.287
7.029IleSer: 7.029 ± 0.829
8.252IleThr: 8.252 ± 1.107
7.946IleVal: 7.946 ± 1.137
0.611IleTrp: 0.611 ± 0.419
5.196IleTyr: 5.196 ± 1.07
0.0IleXaa: 0.0 ± 0.0
Lys
3.973LysAla: 3.973 ± 1.484
0.306LysCys: 0.306 ± 0.336
3.973LysAsp: 3.973 ± 1.222
4.279LysGlu: 4.279 ± 1.488
3.973LysPhe: 3.973 ± 1.361
2.751LysGly: 2.751 ± 0.987
0.917LysHis: 0.917 ± 0.509
6.112LysIle: 6.112 ± 1.658
7.641LysLys: 7.641 ± 1.787
7.335LysLeu: 7.335 ± 1.792
1.528LysMet: 1.528 ± 0.545
4.584LysAsn: 4.584 ± 1.315
2.751LysPro: 2.751 ± 1.039
2.751LysGln: 2.751 ± 1.091
5.196LysArg: 5.196 ± 1.504
3.667LysSer: 3.667 ± 1.32
2.751LysThr: 2.751 ± 0.816
4.89LysVal: 4.89 ± 1.721
0.917LysTrp: 0.917 ± 0.824
2.139LysTyr: 2.139 ± 1.324
0.0LysXaa: 0.0 ± 0.0
Leu
6.418LeuAla: 6.418 ± 1.322
0.0LeuCys: 0.0 ± 0.0
3.362LeuAsp: 3.362 ± 1.196
5.807LeuGlu: 5.807 ± 1.174
5.196LeuPhe: 5.196 ± 1.137
5.807LeuGly: 5.807 ± 1.694
0.0LeuHis: 0.0 ± 0.0
9.169LeuIle: 9.169 ± 2.0
6.418LeuLys: 6.418 ± 2.19
9.169LeuLeu: 9.169 ± 2.412
3.362LeuMet: 3.362 ± 0.878
8.557LeuAsn: 8.557 ± 1.979
3.362LeuPro: 3.362 ± 0.805
2.139LeuGln: 2.139 ± 0.962
2.751LeuArg: 2.751 ± 1.246
5.501LeuSer: 5.501 ± 1.028
7.029LeuThr: 7.029 ± 1.885
3.973LeuVal: 3.973 ± 0.887
1.528LeuTrp: 1.528 ± 0.586
2.751LeuTyr: 2.751 ± 0.707
0.0LeuXaa: 0.0 ± 0.0
Met
0.611MetAla: 0.611 ± 0.418
0.0MetCys: 0.0 ± 0.0
1.834MetAsp: 1.834 ± 0.874
2.139MetGlu: 2.139 ± 0.739
0.611MetPhe: 0.611 ± 0.546
0.306MetGly: 0.306 ± 0.273
0.0MetHis: 0.0 ± 0.0
1.834MetIle: 1.834 ± 0.687
2.139MetLys: 2.139 ± 0.79
0.917MetLeu: 0.917 ± 0.437
1.222MetMet: 1.222 ± 0.62
1.528MetAsn: 1.528 ± 0.758
0.0MetPro: 0.0 ± 0.0
2.139MetGln: 2.139 ± 0.651
0.306MetArg: 0.306 ± 0.302
1.222MetSer: 1.222 ± 0.528
0.917MetThr: 0.917 ± 0.573
1.528MetVal: 1.528 ± 0.736
0.0MetTrp: 0.0 ± 0.0
0.306MetTyr: 0.306 ± 0.273
0.0MetXaa: 0.0 ± 0.0
Asn
5.196AsnAla: 5.196 ± 1.569
0.0AsnCys: 0.0 ± 0.0
5.501AsnAsp: 5.501 ± 1.227
3.667AsnGlu: 3.667 ± 1.124
2.139AsnPhe: 2.139 ± 1.0
3.973AsnGly: 3.973 ± 0.999
1.528AsnHis: 1.528 ± 0.572
8.252AsnIle: 8.252 ± 1.788
4.584AsnLys: 4.584 ± 1.029
4.584AsnLeu: 4.584 ± 1.094
1.222AsnMet: 1.222 ± 0.496
3.667AsnAsn: 3.667 ± 0.823
4.279AsnPro: 4.279 ± 1.13
2.751AsnGln: 2.751 ± 0.676
1.834AsnArg: 1.834 ± 0.691
3.973AsnSer: 3.973 ± 1.416
3.973AsnThr: 3.973 ± 1.044
4.89AsnVal: 4.89 ± 1.482
0.917AsnTrp: 0.917 ± 0.407
3.973AsnTyr: 3.973 ± 1.295
0.0AsnXaa: 0.0 ± 0.0
Pro
0.611ProAla: 0.611 ± 0.418
0.0ProCys: 0.0 ± 0.0
2.139ProAsp: 2.139 ± 0.515
1.834ProGlu: 1.834 ± 1.135
1.222ProPhe: 1.222 ± 0.636
4.279ProGly: 4.279 ± 1.079
0.306ProHis: 0.306 ± 0.323
1.834ProIle: 1.834 ± 1.115
1.528ProLys: 1.528 ± 0.568
2.445ProLeu: 2.445 ± 0.832
0.306ProMet: 0.306 ± 0.273
2.751ProAsn: 2.751 ± 0.638
0.611ProPro: 0.611 ± 0.281
0.611ProGln: 0.611 ± 0.407
0.611ProArg: 0.611 ± 0.281
1.528ProSer: 1.528 ± 0.503
1.834ProThr: 1.834 ± 0.817
3.056ProVal: 3.056 ± 1.028
0.917ProTrp: 0.917 ± 0.567
0.611ProTyr: 0.611 ± 0.451
0.0ProXaa: 0.0 ± 0.0
Gln
2.139GlnAla: 2.139 ± 1.216
0.0GlnCys: 0.0 ± 0.0
1.528GlnAsp: 1.528 ± 0.395
1.528GlnGlu: 1.528 ± 0.719
1.528GlnPhe: 1.528 ± 0.541
1.528GlnGly: 1.528 ± 0.714
1.528GlnHis: 1.528 ± 0.987
4.584GlnIle: 4.584 ± 1.094
3.362GlnLys: 3.362 ± 1.254
1.528GlnLeu: 1.528 ± 0.591
1.834GlnMet: 1.834 ± 0.622
2.751GlnAsn: 2.751 ± 0.786
0.0GlnPro: 0.0 ± 0.0
0.306GlnGln: 0.306 ± 0.226
1.222GlnArg: 1.222 ± 0.708
1.834GlnSer: 1.834 ± 0.798
2.139GlnThr: 2.139 ± 0.738
2.139GlnVal: 2.139 ± 0.605
0.611GlnTrp: 0.611 ± 0.401
1.222GlnTyr: 1.222 ± 0.769
0.0GlnXaa: 0.0 ± 0.0
Arg
1.222ArgAla: 1.222 ± 0.447
0.0ArgCys: 0.0 ± 0.0
1.834ArgAsp: 1.834 ± 0.729
1.222ArgGlu: 1.222 ± 0.811
2.445ArgPhe: 2.445 ± 0.692
0.306ArgGly: 0.306 ± 0.353
0.611ArgHis: 0.611 ± 0.41
5.196ArgIle: 5.196 ± 1.493
5.501ArgLys: 5.501 ± 1.995
2.751ArgLeu: 2.751 ± 0.909
0.306ArgMet: 0.306 ± 0.273
1.222ArgAsn: 1.222 ± 0.575
0.306ArgPro: 0.306 ± 0.273
0.917ArgGln: 0.917 ± 0.53
0.306ArgArg: 0.306 ± 0.361
2.139ArgSer: 2.139 ± 0.905
3.362ArgThr: 3.362 ± 0.875
2.445ArgVal: 2.445 ± 0.977
0.611ArgTrp: 0.611 ± 0.438
1.528ArgTyr: 1.528 ± 0.761
0.0ArgXaa: 0.0 ± 0.0
Ser
1.834SerAla: 1.834 ± 0.572
0.306SerCys: 0.306 ± 0.347
7.335SerAsp: 7.335 ± 1.777
3.362SerGlu: 3.362 ± 1.071
4.279SerPhe: 4.279 ± 0.972
4.279SerGly: 4.279 ± 0.842
0.611SerHis: 0.611 ± 0.451
7.641SerIle: 7.641 ± 1.396
3.667SerLys: 3.667 ± 1.477
6.112SerLeu: 6.112 ± 1.402
0.917SerMet: 0.917 ± 0.572
3.973SerAsn: 3.973 ± 0.908
2.139SerPro: 2.139 ± 0.646
0.917SerGln: 0.917 ± 0.48
1.834SerArg: 1.834 ± 0.664
3.056SerSer: 3.056 ± 1.181
4.89SerThr: 4.89 ± 0.873
4.584SerVal: 4.584 ± 1.375
0.611SerTrp: 0.611 ± 0.434
3.362SerTyr: 3.362 ± 0.831
0.0SerXaa: 0.0 ± 0.0
Thr
2.445ThrAla: 2.445 ± 1.04
0.0ThrCys: 0.0 ± 0.0
2.445ThrAsp: 2.445 ± 0.742
3.973ThrGlu: 3.973 ± 0.959
3.362ThrPhe: 3.362 ± 1.533
3.973ThrGly: 3.973 ± 1.048
1.222ThrHis: 1.222 ± 0.711
9.78ThrIle: 9.78 ± 1.886
2.751ThrLys: 2.751 ± 1.12
4.279ThrLeu: 4.279 ± 0.825
0.306ThrMet: 0.306 ± 0.273
4.89ThrAsn: 4.89 ± 0.954
2.139ThrPro: 2.139 ± 0.766
0.917ThrGln: 0.917 ± 0.321
1.834ThrArg: 1.834 ± 0.598
4.279ThrSer: 4.279 ± 1.08
3.056ThrThr: 3.056 ± 0.617
5.501ThrVal: 5.501 ± 3.167
1.528ThrTrp: 1.528 ± 0.801
5.196ThrTyr: 5.196 ± 0.998
0.0ThrXaa: 0.0 ± 0.0
Val
3.667ValAla: 3.667 ± 1.296
0.0ValCys: 0.0 ± 0.0
4.584ValAsp: 4.584 ± 1.173
3.056ValGlu: 3.056 ± 0.99
1.528ValPhe: 1.528 ± 0.528
5.196ValGly: 5.196 ± 1.527
1.528ValHis: 1.528 ± 0.731
6.112ValIle: 6.112 ± 1.712
4.584ValLys: 4.584 ± 1.252
7.335ValLeu: 7.335 ± 1.924
2.139ValMet: 2.139 ± 0.706
3.973ValAsn: 3.973 ± 1.278
1.528ValPro: 1.528 ± 0.651
2.751ValGln: 2.751 ± 0.747
1.222ValArg: 1.222 ± 0.385
5.196ValSer: 5.196 ± 1.974
3.667ValThr: 3.667 ± 1.225
6.112ValVal: 6.112 ± 1.58
1.222ValTrp: 1.222 ± 0.73
3.362ValTyr: 3.362 ± 1.384
0.0ValXaa: 0.0 ± 0.0
Trp
0.917TrpAla: 0.917 ± 0.499
0.0TrpCys: 0.0 ± 0.0
0.611TrpAsp: 0.611 ± 0.286
1.222TrpGlu: 1.222 ± 0.483
0.917TrpPhe: 0.917 ± 0.618
0.917TrpGly: 0.917 ± 0.476
0.0TrpHis: 0.0 ± 0.0
0.611TrpIle: 0.611 ± 0.451
0.611TrpLys: 0.611 ± 0.322
2.139TrpLeu: 2.139 ± 1.055
0.0TrpMet: 0.0 ± 0.0
0.917TrpAsn: 0.917 ± 0.446
0.611TrpPro: 0.611 ± 0.474
0.917TrpGln: 0.917 ± 0.531
0.0TrpArg: 0.0 ± 0.0
0.306TrpSer: 0.306 ± 0.291
0.611TrpThr: 0.611 ± 0.401
1.528TrpVal: 1.528 ± 0.599
1.222TrpTrp: 1.222 ± 0.873
0.306TrpTyr: 0.306 ± 0.291
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.445TyrAla: 2.445 ± 0.525
0.306TyrCys: 0.306 ± 0.347
3.056TyrAsp: 3.056 ± 0.631
2.751TyrGlu: 2.751 ± 1.049
2.139TyrPhe: 2.139 ± 1.369
2.751TyrGly: 2.751 ± 1.112
1.528TyrHis: 1.528 ± 0.683
4.584TyrIle: 4.584 ± 1.218
3.667TyrLys: 3.667 ± 1.29
5.807TyrLeu: 5.807 ± 0.889
0.611TyrMet: 0.611 ± 0.454
4.279TyrAsn: 4.279 ± 1.248
0.306TyrPro: 0.306 ± 0.273
2.139TyrGln: 2.139 ± 0.676
1.222TyrArg: 1.222 ± 0.739
4.89TyrSer: 4.89 ± 0.913
3.362TyrThr: 3.362 ± 0.978
1.834TyrVal: 1.834 ± 0.567
1.222TyrTrp: 1.222 ± 0.492
2.445TyrTyr: 2.445 ± 0.775
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14 proteins (3273 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski