Amino acid dipepetide frequency for Oryctes borbonicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.22AlaAla: 4.22 ± 0.051	1.087AlaCys: 1.087 ± 0.025	2.852AlaAsp: 2.852 ± 0.03	3.651AlaGlu: 3.651 ± 0.045	2.142AlaPhe: 2.142 ± 0.028	2.957AlaGly: 2.957 ± 0.036	1.262AlaHis: 1.262 ± 0.021	3.57AlaIle: 3.57 ± 0.033	3.76AlaLys: 3.76 ± 0.04	5.397AlaLeu: 5.397 ± 0.052	1.398AlaMet: 1.398 ± 0.021	2.774AlaAsn: 2.774 ± 0.034	2.514AlaPro: 2.514 ± 0.033	2.277AlaGln: 2.277 ± 0.028	2.601AlaArg: 2.601 ± 0.03	4.178AlaSer: 4.178 ± 0.04	3.439AlaThr: 3.439 ± 0.035	3.707AlaVal: 3.707 ± 0.036	0.536AlaTrp: 0.536 ± 0.013	1.664AlaTyr: 1.664 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.046CysAla: 1.046 ± 0.021	0.488CysCys: 0.488 ± 0.016	1.254CysAsp: 1.254 ± 0.024	1.28CysGlu: 1.28 ± 0.026	0.769CysPhe: 0.769 ± 0.016	1.36CysGly: 1.36 ± 0.035	0.505CysHis: 0.505 ± 0.015	1.311CysIle: 1.311 ± 0.031	1.389CysLys: 1.389 ± 0.027	1.865CysLeu: 1.865 ± 0.028	0.409CysMet: 0.409 ± 0.011	1.157CysAsn: 1.157 ± 0.023	1.016CysPro: 1.016 ± 0.034	0.79CysGln: 0.79 ± 0.018	1.026CysArg: 1.026 ± 0.033	1.67CysSer: 1.67 ± 0.04	1.142CysThr: 1.142 ± 0.026	1.237CysVal: 1.237 ± 0.03	0.22CysTrp: 0.22 ± 0.008	0.653CysTyr: 0.653 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	2.822AspAla: 2.822 ± 0.032	1.116AspCys: 1.116 ± 0.024	3.76AspAsp: 3.76 ± 0.05	4.229AspGlu: 4.229 ± 0.046	2.312AspPhe: 2.312 ± 0.028	2.979AspGly: 2.979 ± 0.036	1.129AspHis: 1.129 ± 0.017	4.011AspIle: 4.011 ± 0.039	3.624AspLys: 3.624 ± 0.045	5.07AspLeu: 5.07 ± 0.048	1.263AspMet: 1.263 ± 0.018	3.0AspAsn: 3.0 ± 0.048	2.495AspPro: 2.495 ± 0.039	1.74AspGln: 1.74 ± 0.024	2.512AspArg: 2.512 ± 0.033	4.262AspSer: 4.262 ± 0.046	2.991AspThr: 2.991 ± 0.033	3.736AspVal: 3.736 ± 0.034	0.616AspTrp: 0.616 ± 0.015	1.972AspTyr: 1.972 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	3.785GluAla: 3.785 ± 0.043	1.282GluCys: 1.282 ± 0.042	4.28GluAsp: 4.28 ± 0.042	6.183GluGlu: 6.183 ± 0.079	2.328GluPhe: 2.328 ± 0.025	2.969GluGly: 2.969 ± 0.035	1.509GluHis: 1.509 ± 0.022	4.53GluIle: 4.53 ± 0.051	5.653GluLys: 5.653 ± 0.077	5.894GluLeu: 5.894 ± 0.056	1.624GluMet: 1.624 ± 0.02	4.394GluAsn: 4.394 ± 0.047	2.484GluPro: 2.484 ± 0.036	2.719GluGln: 2.719 ± 0.038	3.521GluArg: 3.521 ± 0.05	4.572GluSer: 4.572 ± 0.046	3.748GluThr: 3.748 ± 0.044	3.887GluVal: 3.887 ± 0.044	0.647GluTrp: 0.647 ± 0.015	2.175GluTyr: 2.175 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	2.065PheAla: 2.065 ± 0.027	0.873PheCys: 0.873 ± 0.018	2.189PheAsp: 2.189 ± 0.028	2.34PheGlu: 2.34 ± 0.029	1.598PhePhe: 1.598 ± 0.026	2.307PheGly: 2.307 ± 0.038	0.96PheHis: 0.96 ± 0.016	2.409PheIle: 2.409 ± 0.027	2.468PheLys: 2.468 ± 0.027	3.771PheLeu: 3.771 ± 0.039	0.839PheMet: 0.839 ± 0.016	2.062PheAsn: 2.062 ± 0.028	1.658PhePro: 1.658 ± 0.025	1.512PheGln: 1.512 ± 0.022	1.844PheArg: 1.844 ± 0.027	3.073PheSer: 3.073 ± 0.035	2.28PheThr: 2.28 ± 0.029	2.443PheVal: 2.443 ± 0.028	0.432PheTrp: 0.432 ± 0.012	1.434PheTyr: 1.434 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	2.871GlyAla: 2.871 ± 0.037	1.008GlyCys: 1.008 ± 0.02	2.912GlyAsp: 2.912 ± 0.038	3.148GlyGlu: 3.148 ± 0.048	2.241GlyPhe: 2.241 ± 0.031	3.507GlyGly: 3.507 ± 0.065	1.317GlyHis: 1.317 ± 0.019	3.351GlyIle: 3.351 ± 0.033	3.572GlyLys: 3.572 ± 0.035	4.34GlyLeu: 4.34 ± 0.045	1.178GlyMet: 1.178 ± 0.02	2.799GlyAsn: 2.799 ± 0.031	2.178GlyPro: 2.178 ± 0.047	1.948GlyGln: 1.948 ± 0.031	2.665GlyArg: 2.665 ± 0.036	4.139GlySer: 4.139 ± 0.049	3.006GlyThr: 3.006 ± 0.034	3.147GlyVal: 3.147 ± 0.034	0.589GlyTrp: 0.589 ± 0.017	2.035GlyTyr: 2.035 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	1.165HisAla: 1.165 ± 0.018	0.583HisCys: 0.583 ± 0.014	1.082HisAsp: 1.082 ± 0.022	1.357HisGlu: 1.357 ± 0.022	1.044HisPhe: 1.044 ± 0.018	1.244HisGly: 1.244 ± 0.021	0.81HisHis: 0.81 ± 0.017	1.623HisIle: 1.623 ± 0.025	1.505HisLys: 1.505 ± 0.022	2.435HisLeu: 2.435 ± 0.033	0.643HisMet: 0.643 ± 0.016	1.222HisAsn: 1.222 ± 0.021	1.255HisPro: 1.255 ± 0.024	1.06HisGln: 1.06 ± 0.02	1.291HisArg: 1.291 ± 0.018	1.885HisSer: 1.885 ± 0.028	1.398HisThr: 1.398 ± 0.024	1.448HisVal: 1.448 ± 0.021	0.281HisTrp: 0.281 ± 0.01	0.911HisTyr: 0.911 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	3.609IleAla: 3.609 ± 0.038	1.5IleCys: 1.5 ± 0.031	3.555IleAsp: 3.555 ± 0.037	4.144IleGlu: 4.144 ± 0.042	2.537IlePhe: 2.537 ± 0.035	3.095IleGly: 3.095 ± 0.034	1.484IleHis: 1.484 ± 0.022	3.976IleIle: 3.976 ± 0.037	4.31IleLys: 4.31 ± 0.037	5.881IleLeu: 5.881 ± 0.054	1.261IleMet: 1.261 ± 0.022	3.45IleAsn: 3.45 ± 0.038	3.325IlePro: 3.325 ± 0.033	2.64IleGln: 2.64 ± 0.034	2.964IleArg: 2.964 ± 0.03	4.858IleSer: 4.858 ± 0.043	3.775IleThr: 3.775 ± 0.037	3.83IleVal: 3.83 ± 0.04	0.605IleTrp: 0.605 ± 0.015	2.036IleTyr: 2.036 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.547LysAla: 3.547 ± 0.039	1.452LysCys: 1.452 ± 0.029	3.901LysAsp: 3.901 ± 0.046	5.418LysGlu: 5.418 ± 0.065	2.464LysPhe: 2.464 ± 0.027	3.047LysGly: 3.047 ± 0.043	1.792LysHis: 1.792 ± 0.028	4.532LysIle: 4.532 ± 0.041	5.865LysLys: 5.865 ± 0.061	6.416LysLeu: 6.416 ± 0.051	1.648LysMet: 1.648 ± 0.024	3.773LysAsn: 3.773 ± 0.035	3.336LysPro: 3.336 ± 0.045	3.072LysGln: 3.072 ± 0.036	3.849LysArg: 3.849 ± 0.046	5.083LysSer: 5.083 ± 0.06	3.902LysThr: 3.902 ± 0.038	4.006LysVal: 4.006 ± 0.039	0.697LysTrp: 0.697 ± 0.015	2.573LysTyr: 2.573 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	5.422LeuAla: 5.422 ± 0.049	1.817LeuCys: 1.817 ± 0.026	4.968LeuAsp: 4.968 ± 0.047	6.365LeuGlu: 6.365 ± 0.07	3.355LeuPhe: 3.355 ± 0.034	4.49LeuGly: 4.49 ± 0.045	2.37LeuHis: 2.37 ± 0.033	4.995LeuIle: 4.995 ± 0.046	6.793LeuLys: 6.793 ± 0.053	8.888LeuLeu: 8.888 ± 0.082	1.955LeuMet: 1.955 ± 0.025	4.931LeuAsn: 4.931 ± 0.043	4.575LeuPro: 4.575 ± 0.045	4.6LeuGln: 4.6 ± 0.052	4.783LeuArg: 4.783 ± 0.044	6.916LeuSer: 6.916 ± 0.05	5.176LeuThr: 5.176 ± 0.047	5.031LeuVal: 5.031 ± 0.053	0.894LeuTrp: 0.894 ± 0.018	2.948LeuTyr: 2.948 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	1.479MetAla: 1.479 ± 0.022	0.464MetCys: 0.464 ± 0.012	1.299MetAsp: 1.299 ± 0.02	1.629MetGlu: 1.629 ± 0.021	0.909MetPhe: 0.909 ± 0.019	1.142MetGly: 1.142 ± 0.021	0.525MetHis: 0.525 ± 0.012	1.161MetIle: 1.161 ± 0.019	1.622MetLys: 1.622 ± 0.023	2.056MetLeu: 2.056 ± 0.027	0.573MetMet: 0.573 ± 0.013	1.16MetAsn: 1.16 ± 0.017	1.028MetPro: 1.028 ± 0.017	1.063MetGln: 1.063 ± 0.019	1.1MetArg: 1.1 ± 0.019	1.692MetSer: 1.692 ± 0.025	1.161MetThr: 1.161 ± 0.018	1.292MetVal: 1.292 ± 0.019	0.24MetTrp: 0.24 ± 0.008	0.775MetTyr: 0.775 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.904AsnAla: 2.904 ± 0.037	1.139AsnCys: 1.139 ± 0.023	2.892AsnAsp: 2.892 ± 0.034	3.629AsnGlu: 3.629 ± 0.04	2.225AsnPhe: 2.225 ± 0.027	3.079AsnGly: 3.079 ± 0.042	1.207AsnHis: 1.207 ± 0.023	4.063AsnIle: 4.063 ± 0.043	3.764AsnLys: 3.764 ± 0.044	5.084AsnLeu: 5.084 ± 0.052	1.28AsnMet: 1.28 ± 0.02	3.578AsnAsn: 3.578 ± 0.046	2.491AsnPro: 2.491 ± 0.035	2.104AsnGln: 2.104 ± 0.028	2.502AsnArg: 2.502 ± 0.027	4.471AsnSer: 4.471 ± 0.048	3.19AsnThr: 3.19 ± 0.035	3.592AsnVal: 3.592 ± 0.034	0.544AsnTrp: 0.544 ± 0.014	1.918AsnTyr: 1.918 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	2.656ProAla: 2.656 ± 0.034	0.795ProCys: 0.795 ± 0.041	2.591ProAsp: 2.591 ± 0.03	3.471ProGlu: 3.471 ± 0.057	1.742ProPhe: 1.742 ± 0.026	2.632ProGly: 2.632 ± 0.069	1.16ProHis: 1.16 ± 0.021	2.921ProIle: 2.921 ± 0.035	3.249ProLys: 3.249 ± 0.045	3.996ProLeu: 3.996 ± 0.041	0.981ProMet: 0.981 ± 0.021	2.625ProAsn: 2.625 ± 0.04	4.016ProPro: 4.016 ± 0.083	2.164ProGln: 2.164 ± 0.041	2.196ProArg: 2.196 ± 0.031	4.045ProSer: 4.045 ± 0.058	3.103ProThr: 3.103 ± 0.04	3.062ProVal: 3.062 ± 0.04	0.46ProTrp: 0.46 ± 0.011	1.599ProTyr: 1.599 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	2.386GlnAla: 2.386 ± 0.034	0.863GlnCys: 0.863 ± 0.024	1.987GlnAsp: 1.987 ± 0.026	2.939GlnGlu: 2.939 ± 0.041	1.464GlnPhe: 1.464 ± 0.024	1.84GlnGly: 1.84 ± 0.027	1.161GlnHis: 1.161 ± 0.022	2.558GlnIle: 2.558 ± 0.033	2.851GlnLys: 2.851 ± 0.038	3.984GlnLeu: 3.984 ± 0.05	0.998GlnMet: 0.998 ± 0.02	2.514GlnAsn: 2.514 ± 0.035	2.028GlnPro: 2.028 ± 0.038	2.89GlnGln: 2.89 ± 0.087	2.235GlnArg: 2.235 ± 0.033	2.951GlnSer: 2.951 ± 0.039	2.414GlnThr: 2.414 ± 0.032	2.338GlnVal: 2.338 ± 0.032	0.435GlnTrp: 0.435 ± 0.011	1.433GlnTyr: 1.433 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	2.532ArgAla: 2.532 ± 0.03	0.993ArgCys: 0.993 ± 0.024	2.631ArgAsp: 2.631 ± 0.031	3.217ArgGlu: 3.217 ± 0.035	1.91ArgPhe: 1.91 ± 0.024	2.468ArgGly: 2.468 ± 0.039	1.345ArgHis: 1.345 ± 0.022	3.023ArgIle: 3.023 ± 0.03	4.03ArgLys: 4.03 ± 0.041	4.445ArgLeu: 4.445 ± 0.043	1.127ArgMet: 1.127 ± 0.017	2.866ArgAsn: 2.866 ± 0.027	2.289ArgPro: 2.289 ± 0.056	2.105ArgGln: 2.105 ± 0.027	3.403ArgArg: 3.403 ± 0.043	3.905ArgSer: 3.905 ± 0.058	2.696ArgThr: 2.696 ± 0.028	2.553ArgVal: 2.553 ± 0.03	0.517ArgTrp: 0.517 ± 0.012	1.714ArgTyr: 1.714 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	4.197SerAla: 4.197 ± 0.039	1.498SerCys: 1.498 ± 0.033	4.559SerAsp: 4.559 ± 0.053	4.911SerGlu: 4.911 ± 0.053	2.846SerPhe: 2.846 ± 0.032	4.327SerGly: 4.327 ± 0.043	1.752SerHis: 1.752 ± 0.024	4.485SerIle: 4.485 ± 0.042	5.181SerLys: 5.181 ± 0.047	6.788SerLeu: 6.788 ± 0.054	1.62SerMet: 1.62 ± 0.022	4.491SerAsn: 4.491 ± 0.045	4.329SerPro: 4.329 ± 0.068	3.106SerGln: 3.106 ± 0.037	3.704SerArg: 3.704 ± 0.05	7.814SerSer: 7.814 ± 0.091	4.957SerThr: 4.957 ± 0.053	4.521SerVal: 4.521 ± 0.039	0.741SerTrp: 0.741 ± 0.014	2.381SerTyr: 2.381 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	3.474ThrAla: 3.474 ± 0.035	1.26ThrCys: 1.26 ± 0.031	3.062ThrAsp: 3.062 ± 0.031	3.709ThrGlu: 3.709 ± 0.038	2.299ThrPhe: 2.299 ± 0.029	3.152ThrGly: 3.152 ± 0.043	1.323ThrHis: 1.323 ± 0.021	3.735ThrIle: 3.735 ± 0.037	3.708ThrLys: 3.708 ± 0.036	5.285ThrLeu: 5.285 ± 0.038	1.222ThrMet: 1.222 ± 0.021	3.194ThrAsn: 3.194 ± 0.035	3.505ThrPro: 3.505 ± 0.052	2.218ThrGln: 2.218 ± 0.034	2.452ThrArg: 2.452 ± 0.028	4.985ThrSer: 4.985 ± 0.051	4.116ThrThr: 4.116 ± 0.069	3.727ThrVal: 3.727 ± 0.034	0.558ThrTrp: 0.558 ± 0.013	1.84ThrTyr: 1.84 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	3.613ValAla: 3.613 ± 0.034	1.364ValCys: 1.364 ± 0.028	3.414ValAsp: 3.414 ± 0.031	3.928ValGlu: 3.928 ± 0.047	2.366ValPhe: 2.366 ± 0.03	2.902ValGly: 2.902 ± 0.033	1.477ValHis: 1.477 ± 0.025	3.855ValIle: 3.855 ± 0.039	4.087ValLys: 4.087 ± 0.038	5.506ValLeu: 5.506 ± 0.048	1.307ValMet: 1.307 ± 0.02	3.17ValAsn: 3.17 ± 0.031	3.055ValPro: 3.055 ± 0.037	2.474ValGln: 2.474 ± 0.036	2.833ValArg: 2.833 ± 0.033	4.409ValSer: 4.409 ± 0.037	3.803ValThr: 3.803 ± 0.036	3.866ValVal: 3.866 ± 0.043	0.632ValTrp: 0.632 ± 0.015	1.904ValTyr: 1.904 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	0.512TrpAla: 0.512 ± 0.015	0.231TrpCys: 0.231 ± 0.009	0.594TrpAsp: 0.594 ± 0.016	0.599TrpGlu: 0.599 ± 0.014	0.439TrpPhe: 0.439 ± 0.012	0.524TrpGly: 0.524 ± 0.012	0.254TrpHis: 0.254 ± 0.008	0.627TrpIle: 0.627 ± 0.013	0.765TrpLys: 0.765 ± 0.015	1.013TrpLeu: 1.013 ± 0.021	0.272TrpMet: 0.272 ± 0.009	0.585TrpAsn: 0.585 ± 0.015	0.373TrpPro: 0.373 ± 0.011	0.425TrpGln: 0.425 ± 0.011	0.566TrpArg: 0.566 ± 0.012	0.776TrpSer: 0.776 ± 0.015	0.571TrpThr: 0.571 ± 0.014	0.553TrpVal: 0.553 ± 0.013	0.153TrpTrp: 0.153 ± 0.007	0.345TrpTyr: 0.345 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.678TyrAla: 1.678 ± 0.025	0.773TyrCys: 0.773 ± 0.018	1.854TyrAsp: 1.854 ± 0.032	2.036TyrGlu: 2.036 ± 0.026	1.566TyrPhe: 1.566 ± 0.025	1.931TyrGly: 1.931 ± 0.027	0.901TyrHis: 0.901 ± 0.017	2.099TyrIle: 2.099 ± 0.028	2.176TyrLys: 2.176 ± 0.03	3.158TyrLeu: 3.158 ± 0.036	0.773TyrMet: 0.773 ± 0.017	1.916TyrAsn: 1.916 ± 0.024	1.514TyrPro: 1.514 ± 0.027	1.365TyrGln: 1.365 ± 0.021	1.723TyrArg: 1.723 ± 0.024	2.523TyrSer: 2.523 ± 0.032	1.956TyrThr: 1.956 ± 0.023	1.989TyrVal: 1.989 ± 0.031	0.379TyrTrp: 0.379 ± 0.01	1.37TyrTyr: 1.37 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8820 proteins (3587004 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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