Amino acid dipepetide frequency for Equus caballus papillomavirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.845AlaAla: 7.845 ± 2.146
1.652AlaCys: 1.652 ± 1.15
3.716AlaAsp: 3.716 ± 1.286
4.955AlaGlu: 4.955 ± 0.595
2.477AlaPhe: 2.477 ± 1.285
5.78AlaGly: 5.78 ± 1.366
1.652AlaHis: 1.652 ± 1.133
3.303AlaIle: 3.303 ± 0.607
3.303AlaLys: 3.303 ± 1.068
5.367AlaLeu: 5.367 ± 1.59
0.413AlaMet: 0.413 ± 0.365
1.239AlaAsn: 1.239 ± 0.681
3.716AlaPro: 3.716 ± 1.321
4.542AlaGln: 4.542 ± 1.235
4.542AlaArg: 4.542 ± 1.262
3.303AlaSer: 3.303 ± 0.805
2.89AlaThr: 2.89 ± 0.705
4.542AlaVal: 4.542 ± 1.457
1.239AlaTrp: 1.239 ± 0.722
1.239AlaTyr: 1.239 ± 0.738
0.0AlaXaa: 0.0 ± 0.0
Cys
1.239CysAla: 1.239 ± 0.833
0.413CysCys: 0.413 ± 0.323
0.826CysAsp: 0.826 ± 0.437
0.826CysGlu: 0.826 ± 0.437
1.652CysPhe: 1.652 ± 1.053
1.652CysGly: 1.652 ± 0.938
0.0CysHis: 0.0 ± 0.0
0.413CysIle: 0.413 ± 0.384
1.652CysLys: 1.652 ± 0.812
2.477CysLeu: 2.477 ± 1.132
0.826CysMet: 0.826 ± 0.389
0.413CysAsn: 0.413 ± 0.468
3.303CysPro: 3.303 ± 0.622
0.826CysGln: 0.826 ± 0.704
1.239CysArg: 1.239 ± 0.684
2.89CysSer: 2.89 ± 0.784
2.064CysThr: 2.064 ± 1.288
1.239CysVal: 1.239 ± 0.976
0.826CysTrp: 0.826 ± 0.389
0.413CysTyr: 0.413 ± 0.323
0.0CysXaa: 0.0 ± 0.0
Asp
4.129AspAla: 4.129 ± 1.019
1.239AspCys: 1.239 ± 0.722
3.716AspAsp: 3.716 ± 1.084
2.89AspGlu: 2.89 ± 0.91
0.413AspPhe: 0.413 ± 0.384
4.129AspGly: 4.129 ± 1.206
0.0AspHis: 0.0 ± 0.0
4.129AspIle: 4.129 ± 1.075
1.652AspLys: 1.652 ± 0.499
4.542AspLeu: 4.542 ± 0.811
0.0AspMet: 0.0 ± 0.0
2.477AspAsn: 2.477 ± 0.548
4.542AspPro: 4.542 ± 1.427
2.477AspGln: 2.477 ± 1.166
2.477AspArg: 2.477 ± 1.163
6.193AspSer: 6.193 ± 1.229
4.542AspThr: 4.542 ± 1.365
4.129AspVal: 4.129 ± 1.703
1.239AspTrp: 1.239 ± 0.615
2.064AspTyr: 2.064 ± 0.903
0.0AspXaa: 0.0 ± 0.0
Glu
3.303GluAla: 3.303 ± 1.024
1.652GluCys: 1.652 ± 1.293
4.129GluAsp: 4.129 ± 0.44
4.955GluGlu: 4.955 ± 1.777
1.652GluPhe: 1.652 ± 1.057
4.129GluGly: 4.129 ± 1.75
0.0GluHis: 0.0 ± 0.0
1.239GluIle: 1.239 ± 0.691
2.477GluLys: 2.477 ± 0.545
6.193GluLeu: 6.193 ± 1.577
2.064GluMet: 2.064 ± 0.74
1.652GluAsn: 1.652 ± 0.616
5.78GluPro: 5.78 ± 1.019
2.477GluGln: 2.477 ± 0.725
4.129GluArg: 4.129 ± 0.581
3.716GluSer: 3.716 ± 1.491
4.129GluThr: 4.129 ± 0.944
4.542GluVal: 4.542 ± 1.294
0.0GluTrp: 0.0 ± 0.0
2.477GluTyr: 2.477 ± 1.47
0.0GluXaa: 0.0 ± 0.0
Phe
2.477PheAla: 2.477 ± 0.563
1.652PheCys: 1.652 ± 0.74
3.303PheAsp: 3.303 ± 0.688
1.652PheGlu: 1.652 ± 1.043
2.477PhePhe: 2.477 ± 0.74
1.239PheGly: 1.239 ± 0.691
0.413PheHis: 0.413 ± 0.174
0.826PheIle: 0.826 ± 0.515
2.477PheLys: 2.477 ± 0.732
4.129PheLeu: 4.129 ± 0.679
0.413PheMet: 0.413 ± 0.47
1.239PheAsn: 1.239 ± 0.722
1.239PhePro: 1.239 ± 0.681
3.716PheGln: 3.716 ± 0.814
2.477PheArg: 2.477 ± 1.173
1.239PheSer: 1.239 ± 1.08
2.064PheThr: 2.064 ± 0.931
1.239PheVal: 1.239 ± 0.37
2.064PheTrp: 2.064 ± 1.042
1.652PheTyr: 1.652 ± 0.889
0.0PheXaa: 0.0 ± 0.0
Gly
3.716GlyAla: 3.716 ± 1.321
2.064GlyCys: 2.064 ± 0.729
2.477GlyAsp: 2.477 ± 0.994
2.89GlyGlu: 2.89 ± 0.867
2.477GlyPhe: 2.477 ± 0.8
6.606GlyGly: 6.606 ± 2.83
2.064GlyHis: 2.064 ± 0.475
2.89GlyIle: 2.89 ± 0.972
2.477GlyLys: 2.477 ± 1.4
5.367GlyLeu: 5.367 ± 1.185
0.0GlyMet: 0.0 ± 0.0
2.064GlyAsn: 2.064 ± 0.383
5.78GlyPro: 5.78 ± 1.724
2.064GlyGln: 2.064 ± 0.744
6.606GlyArg: 6.606 ± 1.871
8.258GlySer: 8.258 ± 2.073
6.606GlyThr: 6.606 ± 2.917
3.303GlyVal: 3.303 ± 1.447
0.826GlyTrp: 0.826 ± 0.647
2.477GlyTyr: 2.477 ± 0.899
0.0GlyXaa: 0.0 ± 0.0
His
1.239HisAla: 1.239 ± 0.611
0.826HisCys: 0.826 ± 0.535
0.826HisAsp: 0.826 ± 0.73
0.0HisGlu: 0.0 ± 0.0
2.064HisPhe: 2.064 ± 0.41
0.0HisGly: 0.0 ± 0.0
0.413HisHis: 0.413 ± 0.36
0.826HisIle: 0.826 ± 0.401
0.413HisLys: 0.413 ± 0.323
2.89HisLeu: 2.89 ± 1.074
0.0HisMet: 0.0 ± 0.0
0.413HisAsn: 0.413 ± 0.365
2.064HisPro: 2.064 ± 1.132
1.239HisGln: 1.239 ± 0.738
1.239HisArg: 1.239 ± 0.412
0.413HisSer: 0.413 ± 0.323
1.652HisThr: 1.652 ± 0.232
1.652HisVal: 1.652 ± 0.812
0.826HisTrp: 0.826 ± 0.437
0.826HisTyr: 0.826 ± 0.437
0.0HisXaa: 0.0 ± 0.0
Ile
1.239IleAla: 1.239 ± 0.531
2.064IleCys: 2.064 ± 0.788
1.652IleAsp: 1.652 ± 0.616
3.716IleGlu: 3.716 ± 1.279
0.826IlePhe: 0.826 ± 0.438
1.652IleGly: 1.652 ± 1.043
1.652IleHis: 1.652 ± 0.993
0.413IleIle: 0.413 ± 0.323
1.239IleLys: 1.239 ± 0.684
1.239IleLeu: 1.239 ± 0.681
0.413IleMet: 0.413 ± 0.323
1.652IleAsn: 1.652 ± 0.618
2.477IlePro: 2.477 ± 0.845
0.413IleGln: 0.413 ± 0.384
0.413IleArg: 0.413 ± 0.603
2.064IleSer: 2.064 ± 0.846
2.477IleThr: 2.477 ± 1.255
2.477IleVal: 2.477 ± 1.433
0.413IleTrp: 0.413 ± 0.468
2.477IleTyr: 2.477 ± 1.39
0.0IleXaa: 0.0 ± 0.0
Lys
2.477LysAla: 2.477 ± 0.816
1.652LysCys: 1.652 ± 0.641
2.477LysAsp: 2.477 ± 1.167
1.652LysGlu: 1.652 ± 1.066
0.826LysPhe: 0.826 ± 0.389
3.303LysGly: 3.303 ± 1.384
1.239LysHis: 1.239 ± 0.768
1.239LysIle: 1.239 ± 0.684
1.652LysLys: 1.652 ± 0.814
4.129LysLeu: 4.129 ± 1.341
0.826LysMet: 0.826 ± 0.392
1.239LysAsn: 1.239 ± 0.409
2.89LysPro: 2.89 ± 1.194
1.239LysGln: 1.239 ± 0.518
4.955LysArg: 4.955 ± 0.936
2.89LysSer: 2.89 ± 1.188
3.716LysThr: 3.716 ± 1.078
2.89LysVal: 2.89 ± 1.056
0.413LysTrp: 0.413 ± 0.468
1.652LysTyr: 1.652 ± 0.715
0.0LysXaa: 0.0 ± 0.0
Leu
6.193LeuAla: 6.193 ± 0.92
2.064LeuCys: 2.064 ± 0.884
5.78LeuAsp: 5.78 ± 1.356
5.367LeuGlu: 5.367 ± 1.138
5.78LeuPhe: 5.78 ± 1.67
7.432LeuGly: 7.432 ± 1.382
2.064LeuHis: 2.064 ± 0.446
2.064LeuIle: 2.064 ± 0.903
5.78LeuLys: 5.78 ± 2.03
9.909LeuLeu: 9.909 ± 0.983
0.413LeuMet: 0.413 ± 0.384
0.826LeuAsn: 0.826 ± 0.401
5.367LeuPro: 5.367 ± 1.84
5.367LeuGln: 5.367 ± 0.959
5.78LeuArg: 5.78 ± 1.576
9.083LeuSer: 9.083 ± 1.939
5.367LeuThr: 5.367 ± 1.531
6.193LeuVal: 6.193 ± 0.675
0.413LeuTrp: 0.413 ± 0.323
3.303LeuTyr: 3.303 ± 1.886
0.0LeuXaa: 0.0 ± 0.0
Met
0.826MetAla: 0.826 ± 0.459
0.0MetCys: 0.0 ± 0.0
1.239MetAsp: 1.239 ± 0.722
0.413MetGlu: 0.413 ± 0.384
0.413MetPhe: 0.413 ± 0.365
0.0MetGly: 0.0 ± 0.0
0.413MetHis: 0.413 ± 0.384
0.826MetIle: 0.826 ± 0.438
0.413MetLys: 0.413 ± 0.323
1.652MetLeu: 1.652 ± 0.936
0.413MetMet: 0.413 ± 0.384
0.413MetAsn: 0.413 ± 0.365
0.0MetPro: 0.0 ± 0.0
0.413MetGln: 0.413 ± 0.384
0.826MetArg: 0.826 ± 0.437
2.064MetSer: 2.064 ± 0.573
0.826MetThr: 0.826 ± 0.437
1.652MetVal: 1.652 ± 1.293
0.413MetTrp: 0.413 ± 0.384
0.826MetTyr: 0.826 ± 0.73
0.0MetXaa: 0.0 ± 0.0
Asn
3.303AsnAla: 3.303 ± 1.311
0.0AsnCys: 0.0 ± 0.0
1.239AsnAsp: 1.239 ± 0.634
3.303AsnGlu: 3.303 ± 1.156
0.826AsnPhe: 0.826 ± 0.459
2.064AsnGly: 2.064 ± 0.735
0.413AsnHis: 0.413 ± 0.468
0.826AsnIle: 0.826 ± 0.73
2.477AsnLys: 2.477 ± 2.19
2.064AsnLeu: 2.064 ± 0.977
0.0AsnMet: 0.0 ± 0.0
1.239AsnAsn: 1.239 ± 0.735
2.477AsnPro: 2.477 ± 0.769
2.064AsnGln: 2.064 ± 0.882
2.477AsnArg: 2.477 ± 0.834
0.413AsnSer: 0.413 ± 0.323
1.239AsnThr: 1.239 ± 0.722
0.413AsnVal: 0.413 ± 0.365
0.826AsnTrp: 0.826 ± 0.437
0.826AsnTyr: 0.826 ± 0.647
0.0AsnXaa: 0.0 ± 0.0
Pro
6.606ProAla: 6.606 ± 1.786
3.303ProCys: 3.303 ± 1.483
6.606ProAsp: 6.606 ± 0.922
6.193ProGlu: 6.193 ± 2.047
1.652ProPhe: 1.652 ± 0.714
5.78ProGly: 5.78 ± 1.733
1.239ProHis: 1.239 ± 0.715
3.716ProIle: 3.716 ± 1.04
1.652ProLys: 1.652 ± 0.778
7.432ProLeu: 7.432 ± 1.853
0.826ProMet: 0.826 ± 0.535
2.064ProAsn: 2.064 ± 0.7
7.845ProPro: 7.845 ± 1.874
2.477ProGln: 2.477 ± 0.934
2.89ProArg: 2.89 ± 1.142
3.716ProSer: 3.716 ± 1.236
4.129ProThr: 4.129 ± 0.816
3.303ProVal: 3.303 ± 1.01
0.826ProTrp: 0.826 ± 0.768
2.89ProTyr: 2.89 ± 1.916
0.0ProXaa: 0.0 ± 0.0
Gln
3.303GlnAla: 3.303 ± 0.759
0.0GlnCys: 0.0 ± 0.0
2.064GlnAsp: 2.064 ± 0.808
2.89GlnGlu: 2.89 ± 1.445
0.826GlnPhe: 0.826 ± 0.459
2.89GlnGly: 2.89 ± 0.86
0.413GlnHis: 0.413 ± 0.415
1.239GlnIle: 1.239 ± 0.712
1.239GlnLys: 1.239 ± 0.615
4.129GlnLeu: 4.129 ± 1.26
2.064GlnMet: 2.064 ± 0.772
2.477GlnAsn: 2.477 ± 0.569
2.477GlnPro: 2.477 ± 0.548
2.89GlnGln: 2.89 ± 1.074
4.542GlnArg: 4.542 ± 1.19
2.477GlnSer: 2.477 ± 0.87
2.477GlnThr: 2.477 ± 0.468
4.542GlnVal: 4.542 ± 1.342
1.239GlnTrp: 1.239 ± 0.634
0.826GlnTyr: 0.826 ± 0.565
0.0GlnXaa: 0.0 ± 0.0
Arg
5.367ArgAla: 5.367 ± 0.648
0.826ArgCys: 0.826 ± 0.437
2.477ArgAsp: 2.477 ± 0.731
3.303ArgGlu: 3.303 ± 0.995
3.716ArgPhe: 3.716 ± 0.776
6.193ArgGly: 6.193 ± 2.483
0.826ArgHis: 0.826 ± 0.725
0.826ArgIle: 0.826 ± 0.626
3.716ArgLys: 3.716 ± 1.206
8.258ArgLeu: 8.258 ± 2.133
2.064ArgMet: 2.064 ± 0.951
3.303ArgAsn: 3.303 ± 1.088
6.193ArgPro: 6.193 ± 0.859
2.89ArgGln: 2.89 ± 0.813
7.845ArgArg: 7.845 ± 1.59
4.129ArgSer: 4.129 ± 1.749
2.89ArgThr: 2.89 ± 1.244
5.367ArgVal: 5.367 ± 1.354
0.826ArgTrp: 0.826 ± 0.515
2.064ArgTyr: 2.064 ± 0.554
0.0ArgXaa: 0.0 ± 0.0
Ser
3.716SerAla: 3.716 ± 0.962
1.239SerCys: 1.239 ± 0.722
4.542SerAsp: 4.542 ± 0.861
6.193SerGlu: 6.193 ± 0.953
2.89SerPhe: 2.89 ± 0.875
6.193SerGly: 6.193 ± 1.44
0.826SerHis: 0.826 ± 0.642
1.652SerIle: 1.652 ± 0.836
1.652SerLys: 1.652 ± 1.118
7.432SerLeu: 7.432 ± 0.83
0.413SerMet: 0.413 ± 0.535
1.239SerAsn: 1.239 ± 0.763
7.019SerPro: 7.019 ± 2.167
1.239SerGln: 1.239 ± 0.681
7.432SerArg: 7.432 ± 1.465
6.193SerSer: 6.193 ± 1.36
5.78SerThr: 5.78 ± 1.1
3.716SerVal: 3.716 ± 1.51
0.413SerTrp: 0.413 ± 0.323
2.89SerTyr: 2.89 ± 0.859
0.0SerXaa: 0.0 ± 0.0
Thr
3.716ThrAla: 3.716 ± 1.111
1.652ThrCys: 1.652 ± 0.966
3.716ThrAsp: 3.716 ± 1.049
2.89ThrGlu: 2.89 ± 1.218
2.064ThrPhe: 2.064 ± 0.711
4.955ThrGly: 4.955 ± 1.653
1.652ThrHis: 1.652 ± 0.572
1.239ThrIle: 1.239 ± 0.722
3.716ThrLys: 3.716 ± 1.212
4.955ThrLeu: 4.955 ± 1.093
1.652ThrMet: 1.652 ± 0.578
1.652ThrAsn: 1.652 ± 0.232
4.955ThrPro: 4.955 ± 1.339
2.89ThrGln: 2.89 ± 1.119
4.129ThrArg: 4.129 ± 0.83
5.78ThrSer: 5.78 ± 1.088
4.542ThrThr: 4.542 ± 1.333
4.955ThrVal: 4.955 ± 0.8
1.239ThrTrp: 1.239 ± 0.683
1.652ThrTyr: 1.652 ± 0.964
0.0ThrXaa: 0.0 ± 0.0
Val
3.716ValAla: 3.716 ± 1.398
1.239ValCys: 1.239 ± 0.697
4.129ValAsp: 4.129 ± 1.596
4.129ValGlu: 4.129 ± 0.875
2.89ValPhe: 2.89 ± 1.612
4.955ValGly: 4.955 ± 1.904
2.477ValHis: 2.477 ± 1.244
2.064ValIle: 2.064 ± 1.374
1.239ValLys: 1.239 ± 0.615
5.78ValLeu: 5.78 ± 1.882
0.826ValMet: 0.826 ± 0.658
2.064ValAsn: 2.064 ± 0.765
4.542ValPro: 4.542 ± 0.999
3.716ValGln: 3.716 ± 1.37
2.89ValArg: 2.89 ± 1.09
4.955ValSer: 4.955 ± 1.065
4.955ValThr: 4.955 ± 1.437
4.542ValVal: 4.542 ± 1.215
1.239ValTrp: 1.239 ± 0.961
2.89ValTyr: 2.89 ± 0.491
0.0ValXaa: 0.0 ± 0.0
Trp
1.652TrpAla: 1.652 ± 0.232
0.413TrpCys: 0.413 ± 0.468
1.239TrpAsp: 1.239 ± 0.37
1.239TrpGlu: 1.239 ± 0.592
1.652TrpPhe: 1.652 ± 0.655
0.413TrpGly: 0.413 ± 0.384
0.413TrpHis: 0.413 ± 0.365
0.0TrpIle: 0.0 ± 0.0
1.652TrpLys: 1.652 ± 1.03
2.064TrpLeu: 2.064 ± 1.208
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.413TrpGln: 0.413 ± 0.323
2.064TrpArg: 2.064 ± 0.967
0.826TrpSer: 0.826 ± 0.437
1.239TrpThr: 1.239 ± 1.152
1.239TrpVal: 1.239 ± 0.615
0.0TrpTrp: 0.0 ± 0.0
0.826TrpTyr: 0.826 ± 0.437
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.652TyrAla: 1.652 ± 0.769
1.239TyrCys: 1.239 ± 0.833
0.826TyrAsp: 0.826 ± 0.438
1.239TyrGlu: 1.239 ± 0.384
0.413TyrPhe: 0.413 ± 0.384
1.652TyrGly: 1.652 ± 0.866
1.652TyrHis: 1.652 ± 0.818
1.239TyrIle: 1.239 ± 0.384
2.477TyrLys: 2.477 ± 0.867
4.542TyrLeu: 4.542 ± 1.148
0.0TyrMet: 0.0 ± 0.0
0.826TyrAsn: 0.826 ± 0.459
2.477TyrPro: 2.477 ± 1.224
1.652TyrGln: 1.652 ± 0.94
4.129TyrArg: 4.129 ± 1.475
2.477TyrSer: 2.477 ± 0.563
0.413TyrThr: 0.413 ± 0.323
3.303TyrVal: 3.303 ± 0.625
2.064TyrTrp: 2.064 ± 0.959
2.477TyrTyr: 2.477 ± 1.182
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2423 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski