Amino acid dipepetide frequency for Tatumella morbirosei

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.213AlaAla: 10.213 ± 0.135
1.055AlaCys: 1.055 ± 0.026
5.146AlaAsp: 5.146 ± 0.077
6.068AlaGlu: 6.068 ± 0.084
3.282AlaPhe: 3.282 ± 0.057
8.568AlaGly: 8.568 ± 0.093
1.672AlaHis: 1.672 ± 0.036
5.622AlaIle: 5.622 ± 0.09
3.262AlaLys: 3.262 ± 0.081
11.08AlaLeu: 11.08 ± 0.118
2.736AlaMet: 2.736 ± 0.049
2.617AlaAsn: 2.617 ± 0.049
3.445AlaPro: 3.445 ± 0.058
3.626AlaGln: 3.626 ± 0.063
5.406AlaArg: 5.406 ± 0.073
5.673AlaSer: 5.673 ± 0.08
4.864AlaThr: 4.864 ± 0.076
6.839AlaVal: 6.839 ± 0.082
1.282AlaTrp: 1.282 ± 0.035
1.97AlaTyr: 1.97 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.877CysAla: 0.877 ± 0.028
0.212CysCys: 0.212 ± 0.014
0.571CysAsp: 0.571 ± 0.02
0.546CysGlu: 0.546 ± 0.02
0.449CysPhe: 0.449 ± 0.022
1.122CysGly: 1.122 ± 0.032
0.359CysHis: 0.359 ± 0.019
0.575CysIle: 0.575 ± 0.026
0.287CysLys: 0.287 ± 0.016
1.136CysLeu: 1.136 ± 0.031
0.225CysMet: 0.225 ± 0.015
0.313CysAsn: 0.313 ± 0.017
0.474CysPro: 0.474 ± 0.023
0.59CysGln: 0.59 ± 0.023
0.678CysArg: 0.678 ± 0.026
0.672CysSer: 0.672 ± 0.023
0.471CysThr: 0.471 ± 0.02
0.651CysVal: 0.651 ± 0.021
0.187CysTrp: 0.187 ± 0.014
0.333CysTyr: 0.333 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
4.466AspAla: 4.466 ± 0.075
0.535AspCys: 0.535 ± 0.022
2.745AspAsp: 2.745 ± 0.052
3.117AspGlu: 3.117 ± 0.06
2.206AspPhe: 2.206 ± 0.045
3.429AspGly: 3.429 ± 0.054
1.134AspHis: 1.134 ± 0.032
3.652AspIle: 3.652 ± 0.057
2.363AspLys: 2.363 ± 0.048
4.559AspLeu: 4.559 ± 0.061
1.302AspMet: 1.302 ± 0.036
2.226AspAsn: 2.226 ± 0.046
2.405AspPro: 2.405 ± 0.041
2.119AspGln: 2.119 ± 0.047
2.571AspArg: 2.571 ± 0.048
3.185AspSer: 3.185 ± 0.051
2.538AspThr: 2.538 ± 0.048
3.305AspVal: 3.305 ± 0.051
0.84AspTrp: 0.84 ± 0.03
1.86AspTyr: 1.86 ± 0.045
0.0AspXaa: 0.0 ± 0.0
Glu
4.877GluAla: 4.877 ± 0.088
0.423GluCys: 0.423 ± 0.024
2.34GluAsp: 2.34 ± 0.051
2.901GluGlu: 2.901 ± 0.072
1.92GluPhe: 1.92 ± 0.043
3.284GluGly: 3.284 ± 0.058
1.335GluHis: 1.335 ± 0.037
3.439GluIle: 3.439 ± 0.054
2.901GluLys: 2.901 ± 0.061
5.852GluLeu: 5.852 ± 0.079
1.593GluMet: 1.593 ± 0.038
2.241GluAsn: 2.241 ± 0.048
1.878GluPro: 1.878 ± 0.039
3.662GluGln: 3.662 ± 0.066
3.061GluArg: 3.061 ± 0.06
2.944GluSer: 2.944 ± 0.051
2.87GluThr: 2.87 ± 0.052
3.488GluVal: 3.488 ± 0.06
0.761GluTrp: 0.761 ± 0.025
1.457GluTyr: 1.457 ± 0.04
0.0GluXaa: 0.0 ± 0.0
Phe
3.429PheAla: 3.429 ± 0.057
0.575PheCys: 0.575 ± 0.023
2.172PheAsp: 2.172 ± 0.044
1.614PheGlu: 1.614 ± 0.04
1.602PhePhe: 1.602 ± 0.044
3.13PheGly: 3.13 ± 0.054
0.814PheHis: 0.814 ± 0.028
2.644PheIle: 2.644 ± 0.057
1.14PheLys: 1.14 ± 0.033
3.34PheLeu: 3.34 ± 0.067
1.035PheMet: 1.035 ± 0.033
1.672PheAsn: 1.672 ± 0.037
1.739PhePro: 1.739 ± 0.039
1.167PheGln: 1.167 ± 0.032
2.17PheArg: 2.17 ± 0.048
3.66PheSer: 3.66 ± 0.065
2.412PheThr: 2.412 ± 0.048
2.35PheVal: 2.35 ± 0.046
0.568PheTrp: 0.568 ± 0.025
1.204PheTyr: 1.204 ± 0.034
0.0PheXaa: 0.0 ± 0.0
Gly
5.994GlyAla: 5.994 ± 0.091
0.983GlyCys: 0.983 ± 0.03
3.534GlyAsp: 3.534 ± 0.063
4.168GlyGlu: 4.168 ± 0.063
3.36GlyPhe: 3.36 ± 0.057
5.463GlyGly: 5.463 ± 0.078
1.787GlyHis: 1.787 ± 0.039
5.328GlyIle: 5.328 ± 0.078
3.885GlyLys: 3.885 ± 0.061
7.638GlyLeu: 7.638 ± 0.088
2.347GlyMet: 2.347 ± 0.048
2.828GlyAsn: 2.828 ± 0.05
2.324GlyPro: 2.324 ± 0.045
3.351GlyGln: 3.351 ± 0.056
4.009GlyArg: 4.009 ± 0.059
4.618GlySer: 4.618 ± 0.06
3.787GlyThr: 3.787 ± 0.058
5.539GlyVal: 5.539 ± 0.071
1.335GlyTrp: 1.335 ± 0.037
2.688GlyTyr: 2.688 ± 0.05
0.0GlyXaa: 0.0 ± 0.0
His
1.763HisAla: 1.763 ± 0.04
0.379HisCys: 0.379 ± 0.016
1.08HisAsp: 1.08 ± 0.029
0.988HisGlu: 0.988 ± 0.031
1.071HisPhe: 1.071 ± 0.034
1.749HisGly: 1.749 ± 0.04
0.733HisHis: 0.733 ± 0.026
1.335HisIle: 1.335 ± 0.031
0.7HisLys: 0.7 ± 0.024
2.31HisLeu: 2.31 ± 0.047
0.542HisMet: 0.542 ± 0.023
0.819HisAsn: 0.819 ± 0.028
1.491HisPro: 1.491 ± 0.038
1.543HisGln: 1.543 ± 0.038
1.373HisArg: 1.373 ± 0.035
1.484HisSer: 1.484 ± 0.036
1.062HisThr: 1.062 ± 0.031
1.146HisVal: 1.146 ± 0.033
0.538HisTrp: 0.538 ± 0.02
0.982HisTyr: 0.982 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
6.408IleAla: 6.408 ± 0.079
0.736IleCys: 0.736 ± 0.023
3.455IleAsp: 3.455 ± 0.063
3.053IleGlu: 3.053 ± 0.055
2.172IlePhe: 2.172 ± 0.048
4.558IleGly: 4.558 ± 0.065
1.25IleHis: 1.25 ± 0.036
3.684IleIle: 3.684 ± 0.067
2.159IleLys: 2.159 ± 0.051
5.383IleLeu: 5.383 ± 0.093
1.264IleMet: 1.264 ± 0.031
2.535IleAsn: 2.535 ± 0.048
2.961IlePro: 2.961 ± 0.051
1.807IleGln: 1.807 ± 0.04
3.489IleArg: 3.489 ± 0.065
4.517IleSer: 4.517 ± 0.072
3.722IleThr: 3.722 ± 0.057
3.79IleVal: 3.79 ± 0.056
0.616IleTrp: 0.616 ± 0.023
1.525IleTyr: 1.525 ± 0.04
0.0IleXaa: 0.0 ± 0.0
Lys
3.656LysAla: 3.656 ± 0.073
0.204LysCys: 0.204 ± 0.015
1.899LysAsp: 1.899 ± 0.044
1.906LysGlu: 1.906 ± 0.046
1.146LysPhe: 1.146 ± 0.03
2.627LysGly: 2.627 ± 0.051
0.808LysHis: 0.808 ± 0.028
2.531LysIle: 2.531 ± 0.049
2.076LysLys: 2.076 ± 0.046
3.966LysLeu: 3.966 ± 0.054
1.133LysMet: 1.133 ± 0.03
1.699LysAsn: 1.699 ± 0.043
1.925LysPro: 1.925 ± 0.047
2.122LysGln: 2.122 ± 0.052
2.116LysArg: 2.116 ± 0.044
2.267LysSer: 2.267 ± 0.056
2.464LysThr: 2.464 ± 0.053
2.704LysVal: 2.704 ± 0.046
0.387LysTrp: 0.387 ± 0.018
1.099LysTyr: 1.099 ± 0.031
0.0LysXaa: 0.0 ± 0.0
Leu
11.013LeuAla: 11.013 ± 0.102
1.244LeuCys: 1.244 ± 0.038
4.986LeuAsp: 4.986 ± 0.077
5.275LeuGlu: 5.275 ± 0.075
4.249LeuPhe: 4.249 ± 0.077
6.981LeuGly: 6.981 ± 0.098
2.301LeuHis: 2.301 ± 0.04
6.043LeuIle: 6.043 ± 0.086
4.415LeuLys: 4.415 ± 0.061
12.616LeuLeu: 12.616 ± 0.164
2.887LeuMet: 2.887 ± 0.059
4.278LeuAsn: 4.278 ± 0.066
6.196LeuPro: 6.196 ± 0.083
5.213LeuGln: 5.213 ± 0.078
6.085LeuArg: 6.085 ± 0.083
8.502LeuSer: 8.502 ± 0.11
6.74LeuThr: 6.74 ± 0.088
7.096LeuVal: 7.096 ± 0.098
1.419LeuTrp: 1.419 ± 0.042
2.572LeuTyr: 2.572 ± 0.049
0.0LeuXaa: 0.0 ± 0.0
Met
2.7MetAla: 2.7 ± 0.052
0.17MetCys: 0.17 ± 0.011
1.103MetAsp: 1.103 ± 0.035
1.126MetGlu: 1.126 ± 0.034
0.879MetPhe: 0.879 ± 0.029
1.704MetGly: 1.704 ± 0.044
0.524MetHis: 0.524 ± 0.02
1.584MetIle: 1.584 ± 0.035
1.342MetLys: 1.342 ± 0.036
3.022MetLeu: 3.022 ± 0.055
0.835MetMet: 0.835 ± 0.025
1.081MetAsn: 1.081 ± 0.024
1.267MetPro: 1.267 ± 0.034
1.23MetGln: 1.23 ± 0.031
1.31MetArg: 1.31 ± 0.037
1.949MetSer: 1.949 ± 0.044
1.862MetThr: 1.862 ± 0.039
1.862MetVal: 1.862 ± 0.041
0.21MetTrp: 0.21 ± 0.013
0.476MetTyr: 0.476 ± 0.02
0.0MetXaa: 0.0 ± 0.0
Asn
3.152AsnAla: 3.152 ± 0.056
0.354AsnCys: 0.354 ± 0.018
1.95AsnAsp: 1.95 ± 0.048
1.588AsnGlu: 1.588 ± 0.041
1.315AsnPhe: 1.315 ± 0.035
2.789AsnGly: 2.789 ± 0.05
0.915AsnHis: 0.915 ± 0.026
2.448AsnIle: 2.448 ± 0.045
1.452AsnLys: 1.452 ± 0.038
3.439AsnLeu: 3.439 ± 0.05
0.832AsnMet: 0.832 ± 0.025
1.633AsnAsn: 1.633 ± 0.043
2.154AsnPro: 2.154 ± 0.045
1.789AsnGln: 1.789 ± 0.043
1.929AsnArg: 1.929 ± 0.036
2.367AsnSer: 2.367 ± 0.047
1.989AsnThr: 1.989 ± 0.041
2.279AsnVal: 2.279 ± 0.055
0.521AsnTrp: 0.521 ± 0.021
1.166AsnTyr: 1.166 ± 0.033
0.0AsnXaa: 0.0 ± 0.0
Pro
5.137ProAla: 5.137 ± 0.069
0.4ProCys: 0.4 ± 0.017
2.882ProAsp: 2.882 ± 0.059
3.666ProGlu: 3.666 ± 0.064
1.821ProPhe: 1.821 ± 0.04
3.936ProGly: 3.936 ± 0.058
1.005ProHis: 1.005 ± 0.031
1.413ProIle: 1.413 ± 0.034
1.335ProLys: 1.335 ± 0.034
5.379ProLeu: 5.379 ± 0.08
1.057ProMet: 1.057 ± 0.033
1.098ProAsn: 1.098 ± 0.032
1.749ProPro: 1.749 ± 0.049
2.6ProGln: 2.6 ± 0.042
1.963ProArg: 1.963 ± 0.043
2.413ProSer: 2.413 ± 0.045
1.957ProThr: 1.957 ± 0.046
4.593ProVal: 4.593 ± 0.068
0.751ProTrp: 0.751 ± 0.024
1.212ProTyr: 1.212 ± 0.035
0.0ProXaa: 0.0 ± 0.0
Gln
4.84GlnAla: 4.84 ± 0.073
0.418GlnCys: 0.418 ± 0.018
1.911GlnAsp: 1.911 ± 0.039
2.067GlnGlu: 2.067 ± 0.047
1.616GlnPhe: 1.616 ± 0.042
3.611GlnGly: 3.611 ± 0.06
1.427GlnHis: 1.427 ± 0.038
2.537GlnIle: 2.537 ± 0.043
1.788GlnLys: 1.788 ± 0.043
5.939GlnLeu: 5.939 ± 0.087
1.275GlnMet: 1.275 ± 0.027
1.542GlnAsn: 1.542 ± 0.037
2.56GlnPro: 2.56 ± 0.05
4.957GlnGln: 4.957 ± 0.121
3.273GlnArg: 3.273 ± 0.054
2.855GlnSer: 2.855 ± 0.058
2.343GlnThr: 2.343 ± 0.044
3.279GlnVal: 3.279 ± 0.063
0.842GlnTrp: 0.842 ± 0.025
1.293GlnTyr: 1.293 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
4.195ArgAla: 4.195 ± 0.061
0.555ArgCys: 0.555 ± 0.022
2.798ArgAsp: 2.798 ± 0.054
3.64ArgGlu: 3.64 ± 0.068
2.456ArgPhe: 2.456 ± 0.048
3.469ArgGly: 3.469 ± 0.053
1.635ArgHis: 1.635 ± 0.039
3.391ArgIle: 3.391 ± 0.056
2.36ArgLys: 2.36 ± 0.044
6.62ArgLeu: 6.62 ± 0.081
1.534ArgMet: 1.534 ± 0.036
1.967ArgAsn: 1.967 ± 0.041
2.308ArgPro: 2.308 ± 0.047
3.961ArgGln: 3.961 ± 0.059
3.424ArgArg: 3.424 ± 0.071
3.002ArgSer: 3.002 ± 0.048
2.404ArgThr: 2.404 ± 0.045
3.6ArgVal: 3.6 ± 0.052
0.992ArgTrp: 0.992 ± 0.031
2.169ArgTyr: 2.169 ± 0.044
0.0ArgXaa: 0.0 ± 0.0
Ser
6.261SerAla: 6.261 ± 0.082
0.619SerCys: 0.619 ± 0.022
3.523SerAsp: 3.523 ± 0.057
3.651SerGlu: 3.651 ± 0.061
2.517SerPhe: 2.517 ± 0.047
6.033SerGly: 6.033 ± 0.079
1.67SerHis: 1.67 ± 0.033
2.908SerIle: 2.908 ± 0.054
1.976SerLys: 1.976 ± 0.042
7.828SerLeu: 7.828 ± 0.093
1.529SerMet: 1.529 ± 0.034
1.895SerAsn: 1.895 ± 0.041
3.027SerPro: 3.027 ± 0.05
3.217SerGln: 3.217 ± 0.061
3.878SerArg: 3.878 ± 0.056
4.122SerSer: 4.122 ± 0.074
2.981SerThr: 2.981 ± 0.055
4.969SerVal: 4.969 ± 0.077
1.03SerTrp: 1.03 ± 0.03
1.815SerTyr: 1.815 ± 0.039
0.0SerXaa: 0.0 ± 0.0
Thr
5.405ThrAla: 5.405 ± 0.081
0.477ThrCys: 0.477 ± 0.022
2.936ThrAsp: 2.936 ± 0.047
3.079ThrGlu: 3.079 ± 0.05
1.938ThrPhe: 1.938 ± 0.044
4.872ThrGly: 4.872 ± 0.069
1.256ThrHis: 1.256 ± 0.037
2.826ThrIle: 2.826 ± 0.059
1.289ThrLys: 1.289 ± 0.035
7.228ThrLeu: 7.228 ± 0.085
1.021ThrMet: 1.021 ± 0.035
1.447ThrAsn: 1.447 ± 0.041
3.223ThrPro: 3.223 ± 0.056
1.926ThrGln: 1.926 ± 0.043
3.173ThrArg: 3.173 ± 0.048
3.162ThrSer: 3.162 ± 0.05
2.941ThrThr: 2.941 ± 0.057
3.989ThrVal: 3.989 ± 0.069
0.615ThrTrp: 0.615 ± 0.028
1.176ThrTyr: 1.176 ± 0.035
0.0ThrXaa: 0.0 ± 0.0
Val
6.802ValAla: 6.802 ± 0.077
0.799ValCys: 0.799 ± 0.024
3.408ValAsp: 3.408 ± 0.053
3.2ValGlu: 3.2 ± 0.06
2.634ValPhe: 2.634 ± 0.047
4.543ValGly: 4.543 ± 0.07
1.223ValHis: 1.223 ± 0.028
5.042ValIle: 5.042 ± 0.068
2.657ValLys: 2.657 ± 0.047
7.216ValLeu: 7.216 ± 0.091
2.107ValMet: 2.107 ± 0.044
2.718ValAsn: 2.718 ± 0.057
3.033ValPro: 3.033 ± 0.052
2.234ValGln: 2.234 ± 0.045
3.739ValArg: 3.739 ± 0.056
5.353ValSer: 5.353 ± 0.073
4.595ValThr: 4.595 ± 0.059
5.34ValVal: 5.34 ± 0.091
0.937ValTrp: 0.937 ± 0.031
1.62ValTyr: 1.62 ± 0.037
0.0ValXaa: 0.0 ± 0.0
Trp
0.894TrpAla: 0.894 ± 0.029
0.159TrpCys: 0.159 ± 0.012
0.598TrpAsp: 0.598 ± 0.024
0.518TrpGlu: 0.518 ± 0.02
0.675TrpPhe: 0.675 ± 0.025
0.856TrpGly: 0.856 ± 0.031
0.445TrpHis: 0.445 ± 0.021
0.766TrpIle: 0.766 ± 0.03
0.523TrpLys: 0.523 ± 0.023
2.308TrpLeu: 2.308 ± 0.048
0.42TrpMet: 0.42 ± 0.021
0.486TrpAsn: 0.486 ± 0.02
0.672TrpPro: 0.672 ± 0.024
1.341TrpGln: 1.341 ± 0.041
0.937TrpArg: 0.937 ± 0.03
0.818TrpSer: 0.818 ± 0.029
0.549TrpThr: 0.549 ± 0.021
0.871TrpVal: 0.871 ± 0.028
0.221TrpTrp: 0.221 ± 0.013
0.44TrpTyr: 0.44 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.349TyrAla: 2.349 ± 0.044
0.43TyrCys: 0.43 ± 0.019
1.519TyrAsp: 1.519 ± 0.039
1.056TyrGlu: 1.056 ± 0.026
1.131TyrPhe: 1.131 ± 0.033
2.24TyrGly: 2.24 ± 0.049
0.794TyrHis: 0.794 ± 0.028
1.315TyrIle: 1.315 ± 0.034
0.826TyrLys: 0.826 ± 0.029
3.254TyrLeu: 3.254 ± 0.053
0.563TyrMet: 0.563 ± 0.022
0.966TyrAsn: 0.966 ± 0.03
1.535TyrPro: 1.535 ± 0.04
1.918TyrGln: 1.918 ± 0.041
1.895TyrArg: 1.895 ± 0.04
1.882TyrSer: 1.882 ± 0.042
1.43TyrThr: 1.43 ± 0.036
1.512TyrVal: 1.512 ± 0.036
0.444TyrTrp: 0.444 ± 0.019
0.941TyrTyr: 0.941 ± 0.032
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3697 proteins (1154041 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski