Amino acid dipepetide frequency for Apis mellifera associated microvirus 58

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.793AlaAla: 8.793 ± 2.565
0.0AlaCys: 0.0 ± 0.0
5.596AlaAsp: 5.596 ± 1.701
0.799AlaGlu: 0.799 ± 0.8
2.398AlaPhe: 2.398 ± 0.537
6.395AlaGly: 6.395 ± 2.287
2.398AlaHis: 2.398 ± 0.961
1.599AlaIle: 1.599 ± 1.028
3.997AlaLys: 3.997 ± 1.948
4.796AlaLeu: 4.796 ± 0.831
0.799AlaMet: 0.799 ± 0.892
2.398AlaAsn: 2.398 ± 1.512
3.197AlaPro: 3.197 ± 1.3
5.596AlaGln: 5.596 ± 0.595
3.197AlaArg: 3.197 ± 1.946
3.197AlaSer: 3.197 ± 0.735
5.596AlaThr: 5.596 ± 2.876
2.398AlaVal: 2.398 ± 1.245
1.599AlaTrp: 1.599 ± 1.437
1.599AlaTyr: 1.599 ± 0.953
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.799CysAsp: 0.799 ± 0.514
0.0CysGlu: 0.0 ± 0.0
0.799CysPhe: 0.799 ± 0.8
0.799CysGly: 0.799 ± 0.8
0.799CysHis: 0.799 ± 0.514
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.799CysLeu: 0.799 ± 0.8
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.799CysPro: 0.799 ± 0.8
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.599CysThr: 1.599 ± 1.154
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.596AspAla: 5.596 ± 2.336
0.0AspCys: 0.0 ± 0.0
4.796AspAsp: 4.796 ± 2.568
0.0AspGlu: 0.0 ± 0.0
0.799AspPhe: 0.799 ± 0.892
3.197AspGly: 3.197 ± 1.239
1.599AspHis: 1.599 ± 0.953
3.197AspIle: 3.197 ± 1.906
4.796AspLys: 4.796 ± 1.968
11.191AspLeu: 11.191 ± 2.819
0.0AspMet: 0.0 ± 0.0
1.599AspAsn: 1.599 ± 1.028
8.793AspPro: 8.793 ± 1.969
3.197AspGln: 3.197 ± 0.988
0.799AspArg: 0.799 ± 0.514
1.599AspSer: 1.599 ± 1.028
1.599AspThr: 1.599 ± 0.619
2.398AspVal: 2.398 ± 1.542
1.599AspTrp: 1.599 ± 1.028
6.395AspTyr: 6.395 ± 1.111
0.0AspXaa: 0.0 ± 0.0
Glu
6.395GluAla: 6.395 ± 2.528
0.0GluCys: 0.0 ± 0.0
2.398GluAsp: 2.398 ± 0.961
2.398GluGlu: 2.398 ± 0.809
2.398GluPhe: 2.398 ± 0.809
0.799GluGly: 0.799 ± 0.719
2.398GluHis: 2.398 ± 0.878
1.599GluIle: 1.599 ± 0.619
0.799GluLys: 0.799 ± 0.8
5.596GluLeu: 5.596 ± 1.338
1.599GluMet: 1.599 ± 1.154
4.796GluAsn: 4.796 ± 3.503
1.599GluPro: 1.599 ± 0.619
1.599GluGln: 1.599 ± 0.616
3.197GluArg: 3.197 ± 0.735
2.398GluSer: 2.398 ± 0.537
2.398GluThr: 2.398 ± 0.878
1.599GluVal: 1.599 ± 0.616
0.0GluTrp: 0.0 ± 0.0
4.796GluTyr: 4.796 ± 0.711
0.0GluXaa: 0.0 ± 0.0
Phe
1.599PheAla: 1.599 ± 0.619
0.0PheCys: 0.0 ± 0.0
5.596PheAsp: 5.596 ± 2.876
3.197PheGlu: 3.197 ± 1.107
3.197PhePhe: 3.197 ± 1.3
1.599PheGly: 1.599 ± 0.619
0.0PheHis: 0.0 ± 0.0
4.796PheIle: 4.796 ± 0.831
1.599PheLys: 1.599 ± 0.619
2.398PheLeu: 2.398 ± 1.336
1.599PheMet: 1.599 ± 1.312
3.197PheAsn: 3.197 ± 1.926
0.0PhePro: 0.0 ± 0.0
2.398PheGln: 2.398 ± 0.878
2.398PheArg: 2.398 ± 0.961
2.398PheSer: 2.398 ± 0.809
2.398PheThr: 2.398 ± 0.809
1.599PheVal: 1.599 ± 1.028
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.197GlyAla: 3.197 ± 1.946
0.0GlyCys: 0.0 ± 0.0
5.596GlyAsp: 5.596 ± 2.759
2.398GlyGlu: 2.398 ± 0.537
3.197GlyPhe: 3.197 ± 1.107
4.796GlyGly: 4.796 ± 1.217
1.599GlyHis: 1.599 ± 1.028
3.997GlyIle: 3.997 ± 0.91
4.796GlyLys: 4.796 ± 1.217
7.994GlyLeu: 7.994 ± 1.667
2.398GlyMet: 2.398 ± 1.749
6.395GlyAsn: 6.395 ± 1.506
0.799GlyPro: 0.799 ± 0.514
2.398GlyGln: 2.398 ± 0.961
3.197GlyArg: 3.197 ± 0.398
5.596GlySer: 5.596 ± 1.701
3.197GlyThr: 3.197 ± 0.398
2.398GlyVal: 2.398 ± 0.878
0.799GlyTrp: 0.799 ± 0.514
1.599GlyTyr: 1.599 ± 0.616
0.0GlyXaa: 0.0 ± 0.0
His
1.599HisAla: 1.599 ± 0.973
0.0HisCys: 0.0 ± 0.0
2.398HisAsp: 2.398 ± 1.245
0.0HisGlu: 0.0 ± 0.0
1.599HisPhe: 1.599 ± 1.028
1.599HisGly: 1.599 ± 1.028
0.0HisHis: 0.0 ± 0.0
1.599HisIle: 1.599 ± 0.953
1.599HisLys: 1.599 ± 1.012
3.197HisLeu: 3.197 ± 2.114
0.0HisMet: 0.0 ± 0.0
2.398HisAsn: 2.398 ± 0.961
1.599HisPro: 1.599 ± 0.953
0.0HisGln: 0.0 ± 0.0
0.799HisArg: 0.799 ± 0.514
1.599HisSer: 1.599 ± 1.601
1.599HisThr: 1.599 ± 1.154
1.599HisVal: 1.599 ± 0.619
0.799HisTrp: 0.799 ± 0.514
1.599HisTyr: 1.599 ± 1.154
0.0HisXaa: 0.0 ± 0.0
Ile
3.197IleAla: 3.197 ± 2.055
0.0IleCys: 0.0 ± 0.0
0.799IleAsp: 0.799 ± 0.8
3.997IleGlu: 3.997 ± 1.199
3.997IlePhe: 3.997 ± 0.746
3.997IleGly: 3.997 ± 1.788
0.799IleHis: 0.799 ± 0.8
2.398IleIle: 2.398 ± 0.809
3.997IleLys: 3.997 ± 1.348
4.796IleLeu: 4.796 ± 2.261
2.398IleMet: 2.398 ± 0.844
3.197IleAsn: 3.197 ± 1.206
6.395IlePro: 6.395 ± 1.506
0.0IleGln: 0.0 ± 0.0
2.398IleArg: 2.398 ± 0.961
1.599IleSer: 1.599 ± 1.028
4.796IleThr: 4.796 ± 0.713
0.799IleVal: 0.799 ± 0.892
0.0IleTrp: 0.0 ± 0.0
1.599IleTyr: 1.599 ± 0.973
0.0IleXaa: 0.0 ± 0.0
Lys
6.395LysAla: 6.395 ± 1.705
1.599LysCys: 1.599 ± 1.601
0.799LysAsp: 0.799 ± 0.514
2.398LysGlu: 2.398 ± 0.961
2.398LysPhe: 2.398 ± 0.878
6.395LysGly: 6.395 ± 0.853
0.799LysHis: 0.799 ± 0.8
3.197LysIle: 3.197 ± 1.55
3.997LysLys: 3.997 ± 2.813
5.596LysLeu: 5.596 ± 2.452
1.599LysMet: 1.599 ± 0.953
0.799LysAsn: 0.799 ± 0.8
3.197LysPro: 3.197 ± 1.747
2.398LysGln: 2.398 ± 0.858
7.994LysArg: 7.994 ± 4.456
5.596LysSer: 5.596 ± 2.452
2.398LysThr: 2.398 ± 0.537
2.398LysVal: 2.398 ± 0.878
0.799LysTrp: 0.799 ± 0.8
3.997LysTyr: 3.997 ± 2.904
0.0LysXaa: 0.0 ± 0.0
Leu
4.796LeuAla: 4.796 ± 0.839
0.799LeuCys: 0.799 ± 0.514
8.793LeuAsp: 8.793 ± 1.803
3.197LeuGlu: 3.197 ± 1.107
2.398LeuPhe: 2.398 ± 1.336
7.994LeuGly: 7.994 ± 1.148
0.799LeuHis: 0.799 ± 0.8
3.997LeuIle: 3.997 ± 0.746
7.194LeuLys: 7.194 ± 2.009
5.596LeuLeu: 5.596 ± 1.363
2.398LeuMet: 2.398 ± 1.512
6.395LeuAsn: 6.395 ± 1.506
8.793LeuPro: 8.793 ± 3.017
8.793LeuGln: 8.793 ± 0.83
3.997LeuArg: 3.997 ± 2.563
9.592LeuSer: 9.592 ± 1.358
6.395LeuThr: 6.395 ± 1.58
3.197LeuVal: 3.197 ± 0.398
0.799LeuTrp: 0.799 ± 0.514
2.398LeuTyr: 2.398 ± 1.512
0.0LeuXaa: 0.0 ± 0.0
Met
3.197MetAla: 3.197 ± 1.719
0.799MetCys: 0.799 ± 0.8
3.997MetAsp: 3.997 ± 1.091
0.0MetGlu: 0.0 ± 0.0
0.799MetPhe: 0.799 ± 0.514
0.799MetGly: 0.799 ± 0.719
0.799MetHis: 0.799 ± 0.514
3.197MetIle: 3.197 ± 1.206
0.0MetLys: 0.0 ± 0.0
1.599MetLeu: 1.599 ± 1.437
1.599MetMet: 1.599 ± 1.437
0.799MetAsn: 0.799 ± 0.514
1.599MetPro: 1.599 ± 0.616
1.599MetGln: 1.599 ± 1.437
1.599MetArg: 1.599 ± 1.154
2.398MetSer: 2.398 ± 0.537
2.398MetThr: 2.398 ± 1.336
1.599MetVal: 1.599 ± 1.784
0.0MetTrp: 0.0 ± 0.0
0.799MetTyr: 0.799 ± 0.514
0.0MetXaa: 0.0 ± 0.0
Asn
2.398AsnAla: 2.398 ± 2.156
0.0AsnCys: 0.0 ± 0.0
3.197AsnAsp: 3.197 ± 1.3
6.395AsnGlu: 6.395 ± 2.24
1.599AsnPhe: 1.599 ± 0.616
3.197AsnGly: 3.197 ± 1.206
1.599AsnHis: 1.599 ± 1.012
1.599AsnIle: 1.599 ± 0.619
3.197AsnLys: 3.197 ± 1.107
3.997AsnLeu: 3.997 ± 1.771
1.599AsnMet: 1.599 ± 0.616
3.197AsnAsn: 3.197 ± 0.398
3.997AsnPro: 3.997 ± 1.426
1.599AsnGln: 1.599 ± 0.616
3.997AsnArg: 3.997 ± 1.091
3.997AsnSer: 3.997 ± 0.91
4.796AsnThr: 4.796 ± 2.261
3.997AsnVal: 3.997 ± 1.199
0.799AsnTrp: 0.799 ± 0.719
2.398AsnTyr: 2.398 ± 1.63
0.0AsnXaa: 0.0 ± 0.0
Pro
3.997ProAla: 3.997 ± 1.668
0.799ProCys: 0.799 ± 0.8
3.197ProAsp: 3.197 ± 2.64
4.796ProGlu: 4.796 ± 1.074
3.197ProPhe: 3.197 ± 1.232
1.599ProGly: 1.599 ± 1.028
1.599ProHis: 1.599 ± 1.601
3.197ProIle: 3.197 ± 1.3
4.796ProLys: 4.796 ± 1.921
3.997ProLeu: 3.997 ± 0.91
1.599ProMet: 1.599 ± 0.616
5.596ProAsn: 5.596 ± 2.206
0.799ProPro: 0.799 ± 0.514
3.997ProGln: 3.997 ± 0.91
3.997ProArg: 3.997 ± 0.509
2.398ProSer: 2.398 ± 1.542
1.599ProThr: 1.599 ± 1.028
5.596ProVal: 5.596 ± 1.933
0.799ProTrp: 0.799 ± 0.514
2.398ProTyr: 2.398 ± 1.336
0.0ProXaa: 0.0 ± 0.0
Gln
3.197GlnAla: 3.197 ± 1.906
0.0GlnCys: 0.0 ± 0.0
0.799GlnAsp: 0.799 ± 0.514
4.796GlnGlu: 4.796 ± 1.991
0.799GlnPhe: 0.799 ± 0.719
3.197GlnGly: 3.197 ± 0.398
1.599GlnHis: 1.599 ± 1.154
2.398GlnIle: 2.398 ± 1.236
3.197GlnLys: 3.197 ± 1.216
2.398GlnLeu: 2.398 ± 0.878
3.197GlnMet: 3.197 ± 1.489
3.197GlnAsn: 3.197 ± 1.107
0.0GlnPro: 0.0 ± 0.0
5.596GlnGln: 5.596 ± 3.222
5.596GlnArg: 5.596 ± 2.336
0.799GlnSer: 0.799 ± 0.514
4.796GlnThr: 4.796 ± 1.755
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.799GlnTyr: 0.799 ± 0.514
0.0GlnXaa: 0.0 ± 0.0
Arg
1.599ArgAla: 1.599 ± 0.973
0.799ArgCys: 0.799 ± 0.8
2.398ArgAsp: 2.398 ± 1.236
0.799ArgGlu: 0.799 ± 0.514
0.799ArgPhe: 0.799 ± 0.719
0.799ArgGly: 0.799 ± 0.719
0.799ArgHis: 0.799 ± 0.892
4.796ArgIle: 4.796 ± 0.713
5.596ArgLys: 5.596 ± 3.23
8.793ArgLeu: 8.793 ± 2.783
0.799ArgMet: 0.799 ± 0.514
5.596ArgAsn: 5.596 ± 1.701
3.197ArgPro: 3.197 ± 1.206
0.799ArgGln: 0.799 ± 0.8
3.197ArgArg: 3.197 ± 1.021
4.796ArgSer: 4.796 ± 1.397
0.0ArgThr: 0.0 ± 0.0
3.997ArgVal: 3.997 ± 1.346
0.799ArgTrp: 0.799 ± 0.514
4.796ArgTyr: 4.796 ± 0.839
0.0ArgXaa: 0.0 ± 0.0
Ser
2.398SerAla: 2.398 ± 1.542
0.799SerCys: 0.799 ± 0.892
2.398SerAsp: 2.398 ± 0.809
5.596SerGlu: 5.596 ± 2.132
2.398SerPhe: 2.398 ± 0.961
4.796SerGly: 4.796 ± 1.505
2.398SerHis: 2.398 ± 1.245
1.599SerIle: 1.599 ± 1.028
4.796SerLys: 4.796 ± 1.667
8.793SerLeu: 8.793 ± 4.04
1.599SerMet: 1.599 ± 1.437
2.398SerAsn: 2.398 ± 0.809
3.197SerPro: 3.197 ± 1.926
0.799SerGln: 0.799 ± 0.8
3.197SerArg: 3.197 ± 1.232
4.796SerSer: 4.796 ± 3.342
0.799SerThr: 0.799 ± 0.514
3.197SerVal: 3.197 ± 1.3
2.398SerTrp: 2.398 ± 0.809
3.197SerTyr: 3.197 ± 2.114
0.0SerXaa: 0.0 ± 0.0
Thr
3.197ThrAla: 3.197 ± 1.649
0.0ThrCys: 0.0 ± 0.0
3.197ThrAsp: 3.197 ± 1.107
3.197ThrGlu: 3.197 ± 1.264
3.997ThrPhe: 3.997 ± 1.3
5.596ThrGly: 5.596 ± 1.778
0.799ThrHis: 0.799 ± 0.514
3.997ThrIle: 3.997 ± 0.91
3.997ThrLys: 3.997 ± 0.91
5.596ThrLeu: 5.596 ± 1.612
2.398ThrMet: 2.398 ± 0.537
0.799ThrAsn: 0.799 ± 0.719
4.796ThrPro: 4.796 ± 1.618
0.799ThrGln: 0.799 ± 0.719
1.599ThrArg: 1.599 ± 1.028
3.197ThrSer: 3.197 ± 0.398
6.395ThrThr: 6.395 ± 3.391
2.398ThrVal: 2.398 ± 1.245
0.799ThrTrp: 0.799 ± 0.8
1.599ThrTyr: 1.599 ± 0.619
0.0ThrXaa: 0.0 ± 0.0
Val
3.197ValAla: 3.197 ± 1.3
0.0ValCys: 0.0 ± 0.0
1.599ValAsp: 1.599 ± 1.028
3.197ValGlu: 3.197 ± 1.639
1.599ValPhe: 1.599 ± 1.028
3.997ValGly: 3.997 ± 1.668
2.398ValHis: 2.398 ± 0.961
1.599ValIle: 1.599 ± 0.616
2.398ValLys: 2.398 ± 0.858
4.796ValLeu: 4.796 ± 1.998
1.599ValMet: 1.599 ± 1.028
0.799ValAsn: 0.799 ± 0.719
3.997ValPro: 3.997 ± 1.3
0.799ValGln: 0.799 ± 0.514
3.197ValArg: 3.197 ± 2.055
3.197ValSer: 3.197 ± 0.398
2.398ValThr: 2.398 ± 0.537
1.599ValVal: 1.599 ± 1.028
0.0ValTrp: 0.0 ± 0.0
0.799ValTyr: 0.799 ± 0.514
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.799TrpAsp: 0.799 ± 0.514
0.799TrpGlu: 0.799 ± 0.514
0.799TrpPhe: 0.799 ± 0.8
2.398TrpGly: 2.398 ± 0.809
0.799TrpHis: 0.799 ± 0.514
0.0TrpIle: 0.0 ± 0.0
0.799TrpLys: 0.799 ± 0.514
1.599TrpLeu: 1.599 ± 0.619
0.0TrpMet: 0.0 ± 0.0
2.398TrpAsn: 2.398 ± 0.878
0.799TrpPro: 0.799 ± 0.514
1.599TrpGln: 1.599 ± 0.616
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.799TrpTyr: 0.799 ± 0.719
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.599TyrAla: 1.599 ± 0.953
0.799TyrCys: 0.799 ± 0.514
3.997TyrAsp: 3.997 ± 2.06
0.799TyrGlu: 0.799 ± 0.719
1.599TyrPhe: 1.599 ± 0.619
2.398TyrGly: 2.398 ± 1.63
1.599TyrHis: 1.599 ± 1.601
2.398TyrIle: 2.398 ± 1.542
3.197TyrLys: 3.197 ± 2.114
4.796TyrLeu: 4.796 ± 1.667
1.599TyrMet: 1.599 ± 0.619
1.599TyrAsn: 1.599 ± 1.437
2.398TyrPro: 2.398 ± 2.401
2.398TyrGln: 2.398 ± 1.236
0.799TyrArg: 0.799 ± 0.514
2.398TyrSer: 2.398 ± 1.236
3.197TyrThr: 3.197 ± 0.735
2.398TyrVal: 2.398 ± 0.537
1.599TyrTrp: 1.599 ± 1.028
2.398TyrTyr: 2.398 ± 0.809
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1252 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski