Amino acid dipepetide frequency for Bacillus phage GA-1 (Bacteriophage GA-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.457AlaAla: 0.457 ± 0.293
1.219AlaCys: 1.219 ± 0.429
2.286AlaAsp: 2.286 ± 0.559
3.81AlaGlu: 3.81 ± 0.754
1.981AlaPhe: 1.981 ± 0.697
2.743AlaGly: 2.743 ± 0.773
0.914AlaHis: 0.914 ± 0.397
4.877AlaIle: 4.877 ± 0.63
3.657AlaLys: 3.657 ± 0.919
4.267AlaLeu: 4.267 ± 0.905
1.372AlaMet: 1.372 ± 0.446
3.81AlaAsn: 3.81 ± 0.905
1.676AlaPro: 1.676 ± 0.718
2.591AlaGln: 2.591 ± 0.684
1.981AlaArg: 1.981 ± 0.747
1.829AlaSer: 1.829 ± 0.47
3.505AlaThr: 3.505 ± 0.823
3.657AlaVal: 3.657 ± 0.938
0.457AlaTrp: 0.457 ± 0.237
1.981AlaTyr: 1.981 ± 0.445
0.0AlaXaa: 0.0 ± 0.0
Cys
0.762CysAla: 0.762 ± 0.355
0.0CysCys: 0.0 ± 0.0
0.457CysAsp: 0.457 ± 0.282
1.067CysGlu: 1.067 ± 0.37
1.067CysPhe: 1.067 ± 0.424
1.067CysGly: 1.067 ± 0.527
0.305CysHis: 0.305 ± 0.25
0.457CysIle: 0.457 ± 0.321
0.0CysLys: 0.0 ± 0.0
0.152CysLeu: 0.152 ± 0.142
0.152CysMet: 0.152 ± 0.119
0.457CysAsn: 0.457 ± 0.257
0.0CysPro: 0.0 ± 0.0
0.305CysGln: 0.305 ± 0.199
0.305CysArg: 0.305 ± 0.182
0.152CysSer: 0.152 ± 0.162
0.0CysThr: 0.0 ± 0.0
0.61CysVal: 0.61 ± 0.299
0.0CysTrp: 0.0 ± 0.0
0.305CysTyr: 0.305 ± 0.251
0.0CysXaa: 0.0 ± 0.0
Asp
3.353AspAla: 3.353 ± 0.677
0.762AspCys: 0.762 ± 0.491
3.657AspAsp: 3.657 ± 0.763
4.877AspGlu: 4.877 ± 0.894
5.181AspPhe: 5.181 ± 1.168
3.81AspGly: 3.81 ± 0.878
0.762AspHis: 0.762 ± 0.38
4.877AspIle: 4.877 ± 0.918
5.943AspLys: 5.943 ± 0.91
5.334AspLeu: 5.334 ± 0.812
1.372AspMet: 1.372 ± 0.555
3.505AspAsn: 3.505 ± 0.603
2.286AspPro: 2.286 ± 0.704
1.219AspGln: 1.219 ± 0.517
2.286AspArg: 2.286 ± 0.648
3.657AspSer: 3.657 ± 1.089
3.048AspThr: 3.048 ± 0.632
5.334AspVal: 5.334 ± 1.213
0.457AspTrp: 0.457 ± 0.375
3.81AspTyr: 3.81 ± 0.751
0.0AspXaa: 0.0 ± 0.0
Glu
4.877GluAla: 4.877 ± 0.74
1.219GluCys: 1.219 ± 0.464
5.639GluAsp: 5.639 ± 0.779
6.4GluGlu: 6.4 ± 1.437
3.353GluPhe: 3.353 ± 0.66
4.724GluGly: 4.724 ± 0.825
1.067GluHis: 1.067 ± 0.372
5.486GluIle: 5.486 ± 0.747
6.248GluLys: 6.248 ± 1.119
5.486GluLeu: 5.486 ± 0.943
1.981GluMet: 1.981 ± 0.498
4.724GluAsn: 4.724 ± 0.706
1.219GluPro: 1.219 ± 0.458
2.438GluGln: 2.438 ± 0.536
3.657GluArg: 3.657 ± 0.706
3.962GluSer: 3.962 ± 0.752
4.267GluThr: 4.267 ± 0.901
4.572GluVal: 4.572 ± 0.881
1.676GluTrp: 1.676 ± 0.482
3.505GluTyr: 3.505 ± 0.945
0.0GluXaa: 0.0 ± 0.0
Phe
2.438PheAla: 2.438 ± 0.509
0.0PheCys: 0.0 ± 0.0
3.505PheAsp: 3.505 ± 0.639
4.115PheGlu: 4.115 ± 0.678
2.286PhePhe: 2.286 ± 0.723
2.438PheGly: 2.438 ± 0.648
0.914PheHis: 0.914 ± 0.31
4.419PheIle: 4.419 ± 0.99
4.267PheLys: 4.267 ± 0.79
3.2PheLeu: 3.2 ± 0.754
1.829PheMet: 1.829 ± 0.476
4.419PheAsn: 4.419 ± 0.842
1.067PhePro: 1.067 ± 0.347
0.914PheGln: 0.914 ± 0.322
1.981PheArg: 1.981 ± 0.462
2.743PheSer: 2.743 ± 0.656
4.267PheThr: 4.267 ± 0.582
3.2PheVal: 3.2 ± 0.718
0.305PheTrp: 0.305 ± 0.254
2.133PheTyr: 2.133 ± 0.438
0.0PheXaa: 0.0 ± 0.0
Gly
2.438GlyAla: 2.438 ± 0.593
0.457GlyCys: 0.457 ± 0.199
3.048GlyAsp: 3.048 ± 0.597
3.962GlyGlu: 3.962 ± 0.959
4.419GlyPhe: 4.419 ± 0.71
4.419GlyGly: 4.419 ± 0.984
0.762GlyHis: 0.762 ± 0.376
4.267GlyIle: 4.267 ± 0.904
4.724GlyLys: 4.724 ± 0.809
4.419GlyLeu: 4.419 ± 0.824
2.286GlyMet: 2.286 ± 0.543
5.486GlyAsn: 5.486 ± 1.374
0.0GlyPro: 0.0 ± 0.0
2.286GlyGln: 2.286 ± 0.513
2.438GlyArg: 2.438 ± 0.663
3.353GlySer: 3.353 ± 0.893
3.505GlyThr: 3.505 ± 0.804
3.505GlyVal: 3.505 ± 0.619
1.067GlyTrp: 1.067 ± 0.446
3.353GlyTyr: 3.353 ± 0.853
0.0GlyXaa: 0.0 ± 0.0
His
0.914HisAla: 0.914 ± 0.388
0.0HisCys: 0.0 ± 0.0
1.372HisAsp: 1.372 ± 0.515
0.914HisGlu: 0.914 ± 0.443
1.067HisPhe: 1.067 ± 0.473
1.981HisGly: 1.981 ± 0.551
0.457HisHis: 0.457 ± 0.287
1.524HisIle: 1.524 ± 0.444
1.219HisLys: 1.219 ± 0.418
1.219HisLeu: 1.219 ± 0.514
0.152HisMet: 0.152 ± 0.146
0.914HisAsn: 0.914 ± 0.395
0.305HisPro: 0.305 ± 0.251
0.61HisGln: 0.61 ± 0.324
1.067HisArg: 1.067 ± 0.376
0.61HisSer: 0.61 ± 0.296
1.219HisThr: 1.219 ± 0.429
0.914HisVal: 0.914 ± 0.394
0.152HisTrp: 0.152 ± 0.142
1.219HisTyr: 1.219 ± 0.456
0.0HisXaa: 0.0 ± 0.0
Ile
3.048IleAla: 3.048 ± 0.63
1.067IleCys: 1.067 ± 0.471
4.572IleAsp: 4.572 ± 0.825
6.248IleGlu: 6.248 ± 1.353
4.267IlePhe: 4.267 ± 0.75
3.505IleGly: 3.505 ± 0.717
1.219IleHis: 1.219 ± 0.458
4.267IleIle: 4.267 ± 1.094
6.096IleLys: 6.096 ± 1.053
5.334IleLeu: 5.334 ± 1.076
1.981IleMet: 1.981 ± 0.676
3.657IleAsn: 3.657 ± 0.584
2.438IlePro: 2.438 ± 0.766
2.895IleGln: 2.895 ± 0.636
2.133IleArg: 2.133 ± 0.567
2.743IleSer: 2.743 ± 0.733
3.962IleThr: 3.962 ± 0.736
4.724IleVal: 4.724 ± 0.788
0.457IleTrp: 0.457 ± 0.226
5.943IleTyr: 5.943 ± 0.981
0.0IleXaa: 0.0 ± 0.0
Lys
3.81LysAla: 3.81 ± 0.907
0.152LysCys: 0.152 ± 0.162
5.334LysAsp: 5.334 ± 0.896
6.553LysGlu: 6.553 ± 1.067
3.353LysPhe: 3.353 ± 0.686
5.181LysGly: 5.181 ± 0.962
1.981LysHis: 1.981 ± 0.556
4.724LysIle: 4.724 ± 0.847
7.01LysLys: 7.01 ± 1.311
8.686LysLeu: 8.686 ± 1.05
3.505LysMet: 3.505 ± 0.972
5.029LysAsn: 5.029 ± 1.356
1.524LysPro: 1.524 ± 0.455
3.505LysGln: 3.505 ± 0.723
2.743LysArg: 2.743 ± 0.641
4.267LysSer: 4.267 ± 0.966
5.486LysThr: 5.486 ± 1.065
4.724LysVal: 4.724 ± 0.912
0.762LysTrp: 0.762 ± 0.288
3.2LysTyr: 3.2 ± 0.86
0.0LysXaa: 0.0 ± 0.0
Leu
4.419LeuAla: 4.419 ± 0.713
0.152LeuCys: 0.152 ± 0.142
4.877LeuAsp: 4.877 ± 1.187
5.486LeuGlu: 5.486 ± 1.076
3.657LeuPhe: 3.657 ± 0.816
4.572LeuGly: 4.572 ± 0.894
1.676LeuHis: 1.676 ± 0.567
4.419LeuIle: 4.419 ± 0.717
7.467LeuLys: 7.467 ± 1.376
6.096LeuLeu: 6.096 ± 0.845
2.286LeuMet: 2.286 ± 0.674
5.334LeuAsn: 5.334 ± 1.101
2.591LeuPro: 2.591 ± 0.61
2.286LeuGln: 2.286 ± 0.461
3.2LeuArg: 3.2 ± 0.683
7.467LeuSer: 7.467 ± 0.993
5.486LeuThr: 5.486 ± 0.921
5.181LeuVal: 5.181 ± 0.813
0.914LeuTrp: 0.914 ± 0.286
4.115LeuTyr: 4.115 ± 0.68
0.0LeuXaa: 0.0 ± 0.0
Met
1.676MetAla: 1.676 ± 0.491
0.0MetCys: 0.0 ± 0.0
3.048MetAsp: 3.048 ± 0.616
1.372MetGlu: 1.372 ± 0.417
1.981MetPhe: 1.981 ± 0.636
1.524MetGly: 1.524 ± 0.405
0.61MetHis: 0.61 ± 0.317
1.524MetIle: 1.524 ± 0.577
1.676MetLys: 1.676 ± 0.53
2.286MetLeu: 2.286 ± 0.537
0.457MetMet: 0.457 ± 0.272
1.219MetAsn: 1.219 ± 0.481
1.219MetPro: 1.219 ± 0.51
0.762MetGln: 0.762 ± 0.345
1.219MetArg: 1.219 ± 0.509
2.895MetSer: 2.895 ± 0.695
2.438MetThr: 2.438 ± 0.521
1.524MetVal: 1.524 ± 0.546
0.0MetTrp: 0.0 ± 0.0
1.524MetTyr: 1.524 ± 0.406
0.0MetXaa: 0.0 ± 0.0
Asn
4.724AsnAla: 4.724 ± 0.972
0.152AsnCys: 0.152 ± 0.146
3.962AsnAsp: 3.962 ± 0.798
4.572AsnGlu: 4.572 ± 0.714
1.372AsnPhe: 1.372 ± 0.468
3.962AsnGly: 3.962 ± 0.93
1.219AsnHis: 1.219 ± 0.329
3.81AsnIle: 3.81 ± 0.785
3.962AsnLys: 3.962 ± 0.548
6.096AsnLeu: 6.096 ± 1.203
1.676AsnMet: 1.676 ± 0.461
3.962AsnAsn: 3.962 ± 0.996
2.133AsnPro: 2.133 ± 0.632
1.676AsnGln: 1.676 ± 0.611
2.895AsnArg: 2.895 ± 1.008
4.419AsnSer: 4.419 ± 0.875
4.419AsnThr: 4.419 ± 0.814
4.724AsnVal: 4.724 ± 0.964
0.762AsnTrp: 0.762 ± 0.435
2.895AsnTyr: 2.895 ± 0.725
0.0AsnXaa: 0.0 ± 0.0
Pro
1.372ProAla: 1.372 ± 0.507
0.152ProCys: 0.152 ± 0.148
1.219ProAsp: 1.219 ± 0.433
1.524ProGlu: 1.524 ± 0.395
1.219ProPhe: 1.219 ± 0.413
0.152ProGly: 0.152 ± 0.142
0.0ProHis: 0.0 ± 0.0
1.829ProIle: 1.829 ± 0.414
2.438ProLys: 2.438 ± 0.721
2.591ProLeu: 2.591 ± 0.508
0.914ProMet: 0.914 ± 0.298
2.743ProAsn: 2.743 ± 1.056
0.914ProPro: 0.914 ± 0.278
0.914ProGln: 0.914 ± 0.252
0.762ProArg: 0.762 ± 0.27
1.829ProSer: 1.829 ± 0.574
1.829ProThr: 1.829 ± 0.552
2.591ProVal: 2.591 ± 0.803
0.305ProTrp: 0.305 ± 0.199
1.829ProTyr: 1.829 ± 0.393
0.0ProXaa: 0.0 ± 0.0
Gln
1.219GlnAla: 1.219 ± 0.33
0.305GlnCys: 0.305 ± 0.228
1.829GlnAsp: 1.829 ± 0.515
2.286GlnGlu: 2.286 ± 0.752
1.372GlnPhe: 1.372 ± 0.551
2.591GlnGly: 2.591 ± 0.699
0.457GlnHis: 0.457 ± 0.285
3.048GlnIle: 3.048 ± 0.582
3.048GlnLys: 3.048 ± 0.776
2.133GlnLeu: 2.133 ± 0.529
1.219GlnMet: 1.219 ± 0.489
1.372GlnAsn: 1.372 ± 0.409
1.219GlnPro: 1.219 ± 0.391
0.914GlnGln: 0.914 ± 0.305
1.676GlnArg: 1.676 ± 0.621
1.524GlnSer: 1.524 ± 0.576
2.591GlnThr: 2.591 ± 0.843
2.743GlnVal: 2.743 ± 0.629
1.372GlnTrp: 1.372 ± 0.414
0.914GlnTyr: 0.914 ± 0.349
0.152GlnXaa: 0.152 ± 0.119
Arg
1.829ArgAla: 1.829 ± 0.44
0.152ArgCys: 0.152 ± 0.148
1.829ArgAsp: 1.829 ± 0.539
3.657ArgGlu: 3.657 ± 0.711
2.438ArgPhe: 2.438 ± 0.606
2.133ArgGly: 2.133 ± 0.548
0.914ArgHis: 0.914 ± 0.324
2.895ArgIle: 2.895 ± 0.572
2.591ArgLys: 2.591 ± 0.411
3.657ArgLeu: 3.657 ± 0.726
1.524ArgMet: 1.524 ± 0.412
3.2ArgAsn: 3.2 ± 0.856
1.372ArgPro: 1.372 ± 0.492
1.219ArgGln: 1.219 ± 0.452
1.829ArgArg: 1.829 ± 0.538
1.829ArgSer: 1.829 ± 0.636
2.286ArgThr: 2.286 ± 0.503
1.372ArgVal: 1.372 ± 0.413
0.457ArgTrp: 0.457 ± 0.293
2.591ArgTyr: 2.591 ± 0.69
0.0ArgXaa: 0.0 ± 0.0
Ser
3.353SerAla: 3.353 ± 0.896
0.152SerCys: 0.152 ± 0.164
4.419SerAsp: 4.419 ± 0.755
3.2SerGlu: 3.2 ± 0.655
2.743SerPhe: 2.743 ± 0.566
4.267SerGly: 4.267 ± 0.867
1.219SerHis: 1.219 ± 0.455
3.505SerIle: 3.505 ± 0.784
4.419SerLys: 4.419 ± 1.166
5.486SerLeu: 5.486 ± 0.872
1.829SerMet: 1.829 ± 0.528
3.2SerAsn: 3.2 ± 0.484
1.981SerPro: 1.981 ± 0.556
1.219SerGln: 1.219 ± 0.452
2.133SerArg: 2.133 ± 0.583
2.743SerSer: 2.743 ± 0.701
3.505SerThr: 3.505 ± 0.819
3.505SerVal: 3.505 ± 0.815
0.0SerTrp: 0.0 ± 0.0
3.048SerTyr: 3.048 ± 0.756
0.0SerXaa: 0.0 ± 0.0
Thr
2.743ThrAla: 2.743 ± 0.669
0.457ThrCys: 0.457 ± 0.255
4.877ThrAsp: 4.877 ± 0.869
5.791ThrGlu: 5.791 ± 0.771
2.286ThrPhe: 2.286 ± 0.519
2.743ThrGly: 2.743 ± 0.621
1.067ThrHis: 1.067 ± 0.41
5.791ThrIle: 5.791 ± 1.165
5.791ThrLys: 5.791 ± 0.827
5.334ThrLeu: 5.334 ± 0.981
0.762ThrMet: 0.762 ± 0.354
2.591ThrAsn: 2.591 ± 0.556
1.829ThrPro: 1.829 ± 0.608
2.286ThrGln: 2.286 ± 0.505
3.353ThrArg: 3.353 ± 0.744
3.505ThrSer: 3.505 ± 0.617
3.048ThrThr: 3.048 ± 0.945
4.572ThrVal: 4.572 ± 0.645
1.067ThrTrp: 1.067 ± 0.401
1.829ThrTyr: 1.829 ± 0.65
0.0ThrXaa: 0.0 ± 0.0
Val
2.133ValAla: 2.133 ± 0.539
0.762ValCys: 0.762 ± 0.482
5.791ValAsp: 5.791 ± 1.326
7.01ValGlu: 7.01 ± 1.143
2.591ValPhe: 2.591 ± 0.59
4.572ValGly: 4.572 ± 0.778
1.219ValHis: 1.219 ± 0.449
4.419ValIle: 4.419 ± 0.875
4.267ValLys: 4.267 ± 0.562
5.029ValLeu: 5.029 ± 0.99
1.829ValMet: 1.829 ± 0.515
4.115ValAsn: 4.115 ± 1.308
0.914ValPro: 0.914 ± 0.318
2.895ValGln: 2.895 ± 0.859
2.743ValArg: 2.743 ± 0.733
3.962ValSer: 3.962 ± 0.82
4.267ValThr: 4.267 ± 0.841
4.572ValVal: 4.572 ± 0.746
0.762ValTrp: 0.762 ± 0.28
3.048ValTyr: 3.048 ± 0.607
0.0ValXaa: 0.0 ± 0.0
Trp
0.61TrpAla: 0.61 ± 0.343
0.0TrpCys: 0.0 ± 0.0
0.457TrpAsp: 0.457 ± 0.25
1.067TrpGlu: 1.067 ± 0.492
0.762TrpPhe: 0.762 ± 0.354
0.152TrpGly: 0.152 ± 0.148
0.305TrpHis: 0.305 ± 0.189
0.61TrpIle: 0.61 ± 0.423
1.372TrpLys: 1.372 ± 0.549
1.372TrpLeu: 1.372 ± 0.457
0.61TrpMet: 0.61 ± 0.251
0.61TrpAsn: 0.61 ± 0.237
0.0TrpPro: 0.0 ± 0.0
0.914TrpGln: 0.914 ± 0.309
0.152TrpArg: 0.152 ± 0.164
0.914TrpSer: 0.914 ± 0.358
0.457TrpThr: 0.457 ± 0.3
1.067TrpVal: 1.067 ± 0.383
0.152TrpTrp: 0.152 ± 0.148
0.457TrpTyr: 0.457 ± 0.249
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.895TyrAla: 2.895 ± 0.504
0.457TyrCys: 0.457 ± 0.266
3.353TyrAsp: 3.353 ± 0.708
2.591TyrGlu: 2.591 ± 0.771
3.048TyrPhe: 3.048 ± 0.616
3.657TyrGly: 3.657 ± 0.611
0.762TyrHis: 0.762 ± 0.327
3.81TyrIle: 3.81 ± 0.67
5.334TyrLys: 5.334 ± 0.763
3.505TyrLeu: 3.505 ± 0.643
1.067TyrMet: 1.067 ± 0.402
3.048TyrAsn: 3.048 ± 0.681
2.438TyrPro: 2.438 ± 0.841
2.133TyrGln: 2.133 ± 0.638
1.219TyrArg: 1.219 ± 0.429
1.372TyrSer: 1.372 ± 0.485
2.133TyrThr: 2.133 ± 0.503
3.962TyrVal: 3.962 ± 0.989
0.914TyrTrp: 0.914 ± 0.316
1.372TyrTyr: 1.372 ± 0.371
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.152XaaSer: 0.152 ± 0.119
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 35 proteins (6563 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski