Amino acid dipepetide frequency for Wuhan house centipede virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.427AlaAla: 8.427 ± 2.672
0.0AlaCys: 0.0 ± 0.0
1.404AlaAsp: 1.404 ± 1.171
2.809AlaGlu: 2.809 ± 0.558
3.511AlaPhe: 3.511 ± 0.506
4.213AlaGly: 4.213 ± 1.972
0.702AlaHis: 0.702 ± 0.57
2.809AlaIle: 2.809 ± 0.558
5.618AlaLys: 5.618 ± 3.144
5.618AlaLeu: 5.618 ± 1.67
1.404AlaMet: 1.404 ± 0.537
4.213AlaAsn: 4.213 ± 2.052
7.022AlaPro: 7.022 ± 1.435
1.404AlaGln: 1.404 ± 0.628
4.213AlaArg: 4.213 ± 2.094
7.022AlaSer: 7.022 ± 2.077
2.107AlaThr: 2.107 ± 0.039
5.618AlaVal: 5.618 ± 0.579
2.809AlaTrp: 2.809 ± 1.49
4.213AlaTyr: 4.213 ± 1.098
0.702AlaXaa: 0.702 ± 0.593
Cys
1.404CysAla: 1.404 ± 1.14
0.0CysCys: 0.0 ± 0.0
1.404CysAsp: 1.404 ± 0.537
0.702CysGlu: 0.702 ± 0.593
0.702CysPhe: 0.702 ± 0.585
2.809CysGly: 2.809 ± 1.564
0.702CysHis: 0.702 ± 0.585
0.0CysIle: 0.0 ± 0.0
1.404CysLys: 1.404 ± 1.14
0.702CysLeu: 0.702 ± 0.57
0.0CysMet: 0.0 ± 0.0
1.404CysAsn: 1.404 ± 0.537
0.0CysPro: 0.0 ± 0.0
2.809CysGln: 2.809 ± 0.603
0.0CysArg: 0.0 ± 0.0
1.404CysSer: 1.404 ± 0.628
2.107CysThr: 2.107 ± 0.039
2.809CysVal: 2.809 ± 1.074
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.107AspAla: 2.107 ± 1.026
0.0AspCys: 0.0 ± 0.0
1.404AspAsp: 1.404 ± 0.628
5.618AspGlu: 5.618 ± 2.514
2.809AspPhe: 2.809 ± 0.558
3.511AspGly: 3.511 ± 1.449
1.404AspHis: 1.404 ± 1.14
0.702AspIle: 0.702 ± 0.593
2.809AspLys: 2.809 ± 0.593
6.32AspLeu: 6.32 ± 2.625
2.107AspMet: 2.107 ± 0.938
1.404AspAsn: 1.404 ± 0.537
0.702AspPro: 0.702 ± 0.593
0.0AspGln: 0.0 ± 0.0
3.511AspArg: 3.511 ± 1.151
2.107AspSer: 2.107 ± 1.756
4.213AspThr: 4.213 ± 0.941
5.618AspVal: 5.618 ± 3.896
4.213AspTrp: 4.213 ± 1.087
0.702AspTyr: 0.702 ± 0.593
0.0AspXaa: 0.0 ± 0.0
Glu
4.916GluAla: 4.916 ± 1.484
2.107GluCys: 2.107 ± 1.047
7.022GluAsp: 7.022 ± 0.615
6.32GluGlu: 6.32 ± 2.029
6.32GluPhe: 6.32 ± 0.929
4.916GluGly: 4.916 ± 1.158
1.404GluHis: 1.404 ± 0.537
2.107GluIle: 2.107 ± 0.039
1.404GluLys: 1.404 ± 0.537
2.107GluLeu: 2.107 ± 0.955
0.0GluMet: 0.0 ± 0.0
2.107GluAsn: 2.107 ± 1.026
2.809GluPro: 2.809 ± 0.593
2.107GluGln: 2.107 ± 1.047
8.427GluArg: 8.427 ± 1.166
3.511GluSer: 3.511 ± 1.63
1.404GluThr: 1.404 ± 0.537
4.213GluVal: 4.213 ± 1.087
0.0GluTrp: 0.0 ± 0.0
4.213GluTyr: 4.213 ± 0.929
0.0GluXaa: 0.0 ± 0.0
Phe
2.107PheAla: 2.107 ± 1.779
0.0PheCys: 0.0 ± 0.0
4.213PheAsp: 4.213 ± 0.929
4.213PheGlu: 4.213 ± 1.087
0.0PhePhe: 0.0 ± 0.0
4.213PheGly: 4.213 ± 1.087
0.702PheHis: 0.702 ± 0.57
2.107PheIle: 2.107 ± 1.073
1.404PheLys: 1.404 ± 1.171
2.809PheLeu: 2.809 ± 2.372
0.0PheMet: 0.0 ± 0.0
2.107PheAsn: 2.107 ± 0.968
2.107PhePro: 2.107 ± 0.968
0.702PheGln: 0.702 ± 0.593
2.809PheArg: 2.809 ± 1.257
2.107PheSer: 2.107 ± 0.986
2.809PheThr: 2.809 ± 1.074
2.809PheVal: 2.809 ± 0.603
0.702PheTrp: 0.702 ± 0.593
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.618GlyAla: 5.618 ± 2.573
1.404GlyCys: 1.404 ± 0.628
4.213GlyAsp: 4.213 ± 1.004
2.809GlyGlu: 2.809 ± 1.161
2.809GlyPhe: 2.809 ± 0.558
5.618GlyGly: 5.618 ± 1.206
0.702GlyHis: 0.702 ± 0.57
4.916GlyIle: 4.916 ± 2.348
2.809GlyLys: 2.809 ± 1.61
3.511GlyLeu: 3.511 ± 1.558
2.107GlyMet: 2.107 ± 1.073
2.107GlyAsn: 2.107 ± 0.986
3.511GlyPro: 3.511 ± 1.173
2.809GlyGln: 2.809 ± 1.074
4.213GlyArg: 4.213 ± 1.743
4.916GlySer: 4.916 ± 2.116
7.725GlyThr: 7.725 ± 3.028
4.916GlyVal: 4.916 ± 0.637
1.404GlyTrp: 1.404 ± 0.628
3.511GlyTyr: 3.511 ± 1.173
0.0GlyXaa: 0.0 ± 0.0
His
2.809HisAla: 2.809 ± 1.513
0.702HisCys: 0.702 ± 0.585
1.404HisAsp: 1.404 ± 0.537
0.702HisGlu: 0.702 ± 0.57
1.404HisPhe: 1.404 ± 0.58
0.702HisGly: 0.702 ± 0.57
0.0HisHis: 0.0 ± 0.0
1.404HisIle: 1.404 ± 1.171
0.702HisLys: 0.702 ± 0.585
0.0HisLeu: 0.0 ± 0.0
0.702HisMet: 0.702 ± 0.57
0.0HisAsn: 0.0 ± 0.0
0.702HisPro: 0.702 ± 0.585
0.0HisGln: 0.0 ± 0.0
2.107HisArg: 2.107 ± 0.986
1.404HisSer: 1.404 ± 1.171
0.0HisThr: 0.0 ± 0.0
4.213HisVal: 4.213 ± 1.087
0.0HisTrp: 0.0 ± 0.0
0.702HisTyr: 0.702 ± 0.57
0.0HisXaa: 0.0 ± 0.0
Ile
3.511IleAla: 3.511 ± 1.178
1.404IleCys: 1.404 ± 0.58
0.702IleAsp: 0.702 ± 0.57
3.511IleGlu: 3.511 ± 1.449
1.404IlePhe: 1.404 ± 0.58
6.32IleGly: 6.32 ± 0.983
1.404IleHis: 1.404 ± 0.628
4.213IleIle: 4.213 ± 0.941
2.809IleLys: 2.809 ± 0.593
5.618IleLeu: 5.618 ± 2.188
1.404IleMet: 1.404 ± 1.171
1.404IleAsn: 1.404 ± 0.58
2.107IlePro: 2.107 ± 1.756
0.702IleGln: 0.702 ± 0.593
2.107IleArg: 2.107 ± 0.986
4.213IleSer: 4.213 ± 2.625
2.107IleThr: 2.107 ± 0.986
4.213IleVal: 4.213 ± 2.052
2.107IleTrp: 2.107 ± 1.026
0.702IleTyr: 0.702 ± 0.57
0.0IleXaa: 0.0 ± 0.0
Lys
4.213LysAla: 4.213 ± 1.763
0.702LysCys: 0.702 ± 0.57
1.404LysAsp: 1.404 ± 0.628
2.809LysGlu: 2.809 ± 1.61
0.702LysPhe: 0.702 ± 0.57
4.213LysGly: 4.213 ± 2.664
0.702LysHis: 0.702 ± 0.585
2.809LysIle: 2.809 ± 0.603
2.809LysLys: 2.809 ± 1.513
3.511LysLeu: 3.511 ± 1.173
1.404LysMet: 1.404 ± 0.58
2.107LysAsn: 2.107 ± 0.039
2.809LysPro: 2.809 ± 1.513
1.404LysGln: 1.404 ± 0.537
5.618LysArg: 5.618 ± 1.411
5.618LysSer: 5.618 ± 2.188
0.0LysThr: 0.0 ± 0.0
4.916LysVal: 4.916 ± 0.524
2.809LysTrp: 2.809 ± 0.593
1.404LysTyr: 1.404 ± 1.186
0.0LysXaa: 0.0 ± 0.0
Leu
9.129LeuAla: 9.129 ± 2.519
2.809LeuCys: 2.809 ± 1.61
4.213LeuAsp: 4.213 ± 1.098
4.916LeuGlu: 4.916 ± 3.203
0.702LeuPhe: 0.702 ± 0.57
3.511LeuGly: 3.511 ± 2.047
0.702LeuHis: 0.702 ± 0.593
1.404LeuIle: 1.404 ± 0.537
8.427LeuLys: 8.427 ± 1.957
6.32LeuLeu: 6.32 ± 0.983
0.702LeuMet: 0.702 ± 0.593
1.404LeuAsn: 1.404 ± 1.186
4.213LeuPro: 4.213 ± 1.763
2.809LeuGln: 2.809 ± 1.257
5.618LeuArg: 5.618 ± 1.524
6.32LeuSer: 6.32 ± 1.895
3.511LeuThr: 3.511 ± 1.151
4.213LeuVal: 4.213 ± 1.087
0.702LeuTrp: 0.702 ± 0.585
4.916LeuTyr: 4.916 ± 1.96
0.0LeuXaa: 0.0 ± 0.0
Met
3.511MetAla: 3.511 ± 0.664
1.404MetCys: 1.404 ± 0.628
0.702MetAsp: 0.702 ± 0.585
0.702MetGlu: 0.702 ± 0.57
0.702MetPhe: 0.702 ± 0.585
0.0MetGly: 0.0 ± 0.0
1.404MetHis: 1.404 ± 0.628
0.702MetIle: 0.702 ± 0.593
2.107MetLys: 2.107 ± 1.073
0.702MetLeu: 0.702 ± 0.57
0.0MetMet: 0.0 ± 0.0
1.404MetAsn: 1.404 ± 1.171
1.404MetPro: 1.404 ± 0.628
0.702MetGln: 0.702 ± 0.585
0.702MetArg: 0.702 ± 0.593
2.107MetSer: 2.107 ± 1.026
2.809MetThr: 2.809 ± 0.603
0.702MetVal: 0.702 ± 0.593
0.0MetTrp: 0.0 ± 0.0
2.107MetTyr: 2.107 ± 1.073
0.0MetXaa: 0.0 ± 0.0
Asn
4.213AsnAla: 4.213 ± 1.003
0.0AsnCys: 0.0 ± 0.0
0.702AsnAsp: 0.702 ± 0.585
1.404AsnGlu: 1.404 ± 0.537
2.107AsnPhe: 2.107 ± 1.779
2.809AsnGly: 2.809 ± 0.603
1.404AsnHis: 1.404 ± 1.186
1.404AsnIle: 1.404 ± 0.537
1.404AsnLys: 1.404 ± 0.628
3.511AsnLeu: 3.511 ± 0.578
0.702AsnMet: 0.702 ± 0.593
0.702AsnAsn: 0.702 ± 0.593
0.702AsnPro: 0.702 ± 0.585
2.107AsnGln: 2.107 ± 1.026
1.404AsnArg: 1.404 ± 1.186
2.809AsnSer: 2.809 ± 1.513
2.809AsnThr: 2.809 ± 0.593
0.702AsnVal: 0.702 ± 0.57
0.702AsnTrp: 0.702 ± 0.57
1.404AsnTyr: 1.404 ± 0.537
0.0AsnXaa: 0.0 ± 0.0
Pro
2.107ProAla: 2.107 ± 1.047
0.702ProCys: 0.702 ± 0.593
2.809ProAsp: 2.809 ± 0.603
5.618ProGlu: 5.618 ± 1.687
0.0ProPhe: 0.0 ± 0.0
4.916ProGly: 4.916 ± 1.043
1.404ProHis: 1.404 ± 0.537
3.511ProIle: 3.511 ± 1.178
2.107ProLys: 2.107 ± 1.779
3.511ProLeu: 3.511 ± 2.053
2.107ProMet: 2.107 ± 1.047
0.702ProAsn: 0.702 ± 0.593
2.107ProPro: 2.107 ± 0.968
2.107ProGln: 2.107 ± 1.779
2.809ProArg: 2.809 ± 1.61
5.618ProSer: 5.618 ± 1.411
2.107ProThr: 2.107 ± 0.039
2.107ProVal: 2.107 ± 1.026
2.107ProTrp: 2.107 ± 0.039
2.107ProTyr: 2.107 ± 0.968
0.0ProXaa: 0.0 ± 0.0
Gln
2.809GlnAla: 2.809 ± 1.572
1.404GlnCys: 1.404 ± 0.58
2.809GlnAsp: 2.809 ± 1.572
2.809GlnGlu: 2.809 ± 0.593
0.702GlnPhe: 0.702 ± 0.57
3.511GlnGly: 3.511 ± 0.506
1.404GlnHis: 1.404 ± 0.628
1.404GlnIle: 1.404 ± 0.628
1.404GlnLys: 1.404 ± 0.628
1.404GlnLeu: 1.404 ± 0.537
1.404GlnMet: 1.404 ± 1.171
0.0GlnAsn: 0.0 ± 0.0
2.809GlnPro: 2.809 ± 1.572
2.809GlnGln: 2.809 ± 1.257
1.404GlnArg: 1.404 ± 1.14
2.809GlnSer: 2.809 ± 0.558
2.107GlnThr: 2.107 ± 0.968
4.213GlnVal: 4.213 ± 2.744
0.702GlnTrp: 0.702 ± 0.585
0.702GlnTyr: 0.702 ± 0.57
0.0GlnXaa: 0.0 ± 0.0
Arg
2.107ArgAla: 2.107 ± 0.039
1.404ArgCys: 1.404 ± 0.537
2.107ArgAsp: 2.107 ± 0.039
5.618ArgGlu: 5.618 ± 1.687
4.916ArgPhe: 4.916 ± 2.476
3.511ArgGly: 3.511 ± 0.578
0.702ArgHis: 0.702 ± 0.57
6.32ArgIle: 6.32 ± 1.738
6.32ArgLys: 6.32 ± 0.983
5.618ArgLeu: 5.618 ± 1.186
0.702ArgMet: 0.702 ± 0.585
4.213ArgAsn: 4.213 ± 1.004
2.809ArgPro: 2.809 ± 1.161
4.916ArgGln: 4.916 ± 1.293
4.213ArgArg: 4.213 ± 2.052
2.107ArgSer: 2.107 ± 0.986
4.916ArgThr: 4.916 ± 2.116
3.511ArgVal: 3.511 ± 0.664
2.107ArgTrp: 2.107 ± 1.756
2.107ArgTyr: 2.107 ± 1.756
0.0ArgXaa: 0.0 ± 0.0
Ser
4.916SerAla: 4.916 ± 1.474
1.404SerCys: 1.404 ± 0.58
3.511SerAsp: 3.511 ± 0.506
5.618SerGlu: 5.618 ± 0.701
2.107SerPhe: 2.107 ± 0.955
6.32SerGly: 6.32 ± 1.022
0.702SerHis: 0.702 ± 0.585
3.511SerIle: 3.511 ± 0.578
2.107SerLys: 2.107 ± 0.986
6.32SerLeu: 6.32 ± 1.126
2.809SerMet: 2.809 ± 1.521
1.404SerAsn: 1.404 ± 0.58
4.916SerPro: 4.916 ± 0.603
2.107SerGln: 2.107 ± 0.955
5.618SerArg: 5.618 ± 0.701
4.916SerSer: 4.916 ± 0.637
2.809SerThr: 2.809 ± 1.49
4.213SerVal: 4.213 ± 1.744
2.107SerTrp: 2.107 ± 0.968
2.809SerTyr: 2.809 ± 1.257
0.0SerXaa: 0.0 ± 0.0
Thr
2.809ThrAla: 2.809 ± 1.074
2.809ThrCys: 2.809 ± 0.603
2.809ThrAsp: 2.809 ± 0.558
2.107ThrGlu: 2.107 ± 1.026
1.404ThrPhe: 1.404 ± 1.186
2.107ThrGly: 2.107 ± 0.986
0.702ThrHis: 0.702 ± 0.593
4.916ThrIle: 4.916 ± 0.637
0.702ThrLys: 0.702 ± 0.57
6.32ThrLeu: 6.32 ± 0.929
2.107ThrMet: 2.107 ± 1.046
3.511ThrAsn: 3.511 ± 2.053
2.809ThrPro: 2.809 ± 0.558
3.511ThrGln: 3.511 ± 0.578
4.213ThrArg: 4.213 ± 0.079
2.809ThrSer: 2.809 ± 0.603
4.916ThrThr: 4.916 ± 2.336
2.809ThrVal: 2.809 ± 1.572
0.0ThrTrp: 0.0 ± 0.0
1.404ThrTyr: 1.404 ± 0.628
0.0ThrXaa: 0.0 ± 0.0
Val
3.511ValAla: 3.511 ± 1.63
0.702ValCys: 0.702 ± 0.593
3.511ValAsp: 3.511 ± 2.965
3.511ValGlu: 3.511 ± 2.143
4.213ValPhe: 4.213 ± 1.612
4.213ValGly: 4.213 ± 0.929
1.404ValHis: 1.404 ± 0.628
4.213ValIle: 4.213 ± 0.079
2.107ValLys: 2.107 ± 1.047
6.32ValLeu: 6.32 ± 2.631
0.0ValMet: 0.0 ± 0.0
2.107ValAsn: 2.107 ± 1.047
4.916ValPro: 4.916 ± 0.603
2.809ValGln: 2.809 ± 1.074
5.618ValArg: 5.618 ± 2.046
6.32ValSer: 6.32 ± 1.738
3.511ValThr: 3.511 ± 1.558
3.511ValVal: 3.511 ± 0.664
2.107ValTrp: 2.107 ± 0.955
3.511ValTyr: 3.511 ± 1.173
0.0ValXaa: 0.0 ± 0.0
Trp
2.107TrpAla: 2.107 ± 1.047
0.0TrpCys: 0.0 ± 0.0
1.404TrpAsp: 1.404 ± 1.171
2.809TrpGlu: 2.809 ± 0.558
0.0TrpPhe: 0.0 ± 0.0
2.809TrpGly: 2.809 ± 0.603
0.702TrpHis: 0.702 ± 0.585
0.702TrpIle: 0.702 ± 0.593
2.809TrpLys: 2.809 ± 1.49
2.809TrpLeu: 2.809 ± 0.558
0.702TrpMet: 0.702 ± 0.593
0.702TrpAsn: 0.702 ± 0.593
0.702TrpPro: 0.702 ± 0.585
1.404TrpGln: 1.404 ± 0.537
1.404TrpArg: 1.404 ± 1.171
0.702TrpSer: 0.702 ± 0.585
2.107TrpThr: 2.107 ± 1.073
0.702TrpVal: 0.702 ± 0.57
1.404TrpTrp: 1.404 ± 0.537
0.702TrpTyr: 0.702 ± 0.585
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.511TyrAla: 3.511 ± 1.514
1.404TyrCys: 1.404 ± 0.628
2.809TyrAsp: 2.809 ± 1.61
2.809TyrGlu: 2.809 ± 1.161
1.404TyrPhe: 1.404 ± 1.171
1.404TyrGly: 1.404 ± 0.537
1.404TyrHis: 1.404 ± 0.537
2.809TyrIle: 2.809 ± 0.558
0.702TyrLys: 0.702 ± 0.585
3.511TyrLeu: 3.511 ± 1.178
2.809TyrMet: 2.809 ± 0.593
0.0TyrAsn: 0.0 ± 0.0
1.404TyrPro: 1.404 ± 0.537
1.404TyrGln: 1.404 ± 1.14
4.213TyrArg: 4.213 ± 0.079
2.107TyrSer: 2.107 ± 1.047
0.702TyrThr: 0.702 ± 0.593
2.107TyrVal: 2.107 ± 0.968
0.702TyrTrp: 0.702 ± 0.585
1.404TyrTyr: 1.404 ± 0.537
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.702XaaAsp: 0.702 ± 0.593
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1425 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski