Amino acid dipepetide frequency for Changjiang tombus-like virus 21

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.687AlaAla: 5.687 ± 1.148
0.0AlaCys: 0.0 ± 0.0
3.791AlaAsp: 3.791 ± 0.194
1.896AlaGlu: 1.896 ± 0.761
1.896AlaPhe: 1.896 ± 0.761
2.844AlaGly: 2.844 ± 0.284
1.896AlaHis: 1.896 ± 0.955
4.739AlaIle: 4.739 ± 1.045
1.896AlaLys: 1.896 ± 0.955
4.739AlaLeu: 4.739 ± 1.045
0.0AlaMet: 0.0 ± 0.0
2.844AlaAsn: 2.844 ± 1.432
0.0AlaPro: 0.0 ± 0.0
0.948AlaGln: 0.948 ± 0.477
1.896AlaArg: 1.896 ± 0.761
6.635AlaSer: 6.635 ± 5.238
4.739AlaThr: 4.739 ± 1.045
2.844AlaVal: 2.844 ± 0.284
0.948AlaTrp: 0.948 ± 1.239
0.948AlaTyr: 0.948 ± 0.477
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.948CysCys: 0.948 ± 0.477
0.0CysAsp: 0.0 ± 0.0
0.948CysGlu: 0.948 ± 0.477
1.896CysPhe: 1.896 ± 0.761
1.896CysGly: 1.896 ± 0.761
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.948CysLys: 0.948 ± 0.477
0.948CysLeu: 0.948 ± 0.477
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.948CysPro: 0.948 ± 0.477
0.948CysGln: 0.948 ± 1.239
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.948CysThr: 0.948 ± 0.477
0.948CysVal: 0.948 ± 1.239
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.739AspAla: 4.739 ± 2.387
0.0AspCys: 0.0 ± 0.0
1.896AspAsp: 1.896 ± 0.955
0.948AspGlu: 0.948 ± 0.477
2.844AspPhe: 2.844 ± 2.0
1.896AspGly: 1.896 ± 0.955
1.896AspHis: 1.896 ± 0.955
1.896AspIle: 1.896 ± 0.955
3.791AspLys: 3.791 ± 0.194
6.635AspLeu: 6.635 ± 1.806
1.896AspMet: 1.896 ± 0.955
0.948AspAsn: 0.948 ± 0.477
1.896AspPro: 1.896 ± 0.955
0.948AspGln: 0.948 ± 0.477
0.948AspArg: 0.948 ± 1.239
1.896AspSer: 1.896 ± 0.761
1.896AspThr: 1.896 ± 0.761
2.844AspVal: 2.844 ± 0.284
0.0AspTrp: 0.0 ± 0.0
2.844AspTyr: 2.844 ± 1.432
0.0AspXaa: 0.0 ± 0.0
Glu
1.896GluAla: 1.896 ± 0.955
0.948GluCys: 0.948 ± 0.477
0.948GluAsp: 0.948 ± 0.477
0.948GluGlu: 0.948 ± 0.477
3.791GluPhe: 3.791 ± 1.91
2.844GluGly: 2.844 ± 1.432
0.948GluHis: 0.948 ± 0.477
4.739GluIle: 4.739 ± 2.387
0.948GluLys: 0.948 ± 0.477
2.844GluLeu: 2.844 ± 0.284
0.948GluMet: 0.948 ± 0.477
2.844GluAsn: 2.844 ± 1.432
0.0GluPro: 0.0 ± 0.0
1.896GluGln: 1.896 ± 0.955
0.948GluArg: 0.948 ± 1.239
3.791GluSer: 3.791 ± 3.239
1.896GluThr: 1.896 ± 0.761
1.896GluVal: 1.896 ± 0.955
0.0GluTrp: 0.0 ± 0.0
2.844GluTyr: 2.844 ± 1.432
0.0GluXaa: 0.0 ± 0.0
Phe
0.948PheAla: 0.948 ± 0.477
0.948PheCys: 0.948 ± 0.477
1.896PheAsp: 1.896 ± 0.955
5.687PheGlu: 5.687 ± 1.148
1.896PhePhe: 1.896 ± 2.477
2.844PheGly: 2.844 ± 1.432
1.896PheHis: 1.896 ± 0.955
1.896PheIle: 1.896 ± 0.955
5.687PheLys: 5.687 ± 2.864
2.844PheLeu: 2.844 ± 3.716
0.0PheMet: 0.0 ± 0.0
1.896PheAsn: 1.896 ± 0.761
2.844PhePro: 2.844 ± 0.284
1.896PheGln: 1.896 ± 0.761
1.896PheArg: 1.896 ± 0.955
1.896PheSer: 1.896 ± 0.955
2.844PheThr: 2.844 ± 1.432
3.791PheVal: 3.791 ± 0.194
0.0PheTrp: 0.0 ± 0.0
2.844PheTyr: 2.844 ± 0.284
0.0PheXaa: 0.0 ± 0.0
Gly
3.791GlyAla: 3.791 ± 0.194
0.0GlyCys: 0.0 ± 0.0
6.635GlyAsp: 6.635 ± 1.626
2.844GlyGlu: 2.844 ± 1.432
3.791GlyPhe: 3.791 ± 1.91
6.635GlyGly: 6.635 ± 3.342
1.896GlyHis: 1.896 ± 0.955
0.948GlyIle: 0.948 ± 1.239
1.896GlyLys: 1.896 ± 0.955
7.583GlyLeu: 7.583 ± 3.819
1.896GlyMet: 1.896 ± 0.955
2.844GlyAsn: 2.844 ± 1.432
0.948GlyPro: 0.948 ± 0.477
1.896GlyGln: 1.896 ± 0.955
0.948GlyArg: 0.948 ± 1.239
5.687GlySer: 5.687 ± 0.568
7.583GlyThr: 7.583 ± 1.329
3.791GlyVal: 3.791 ± 0.194
0.948GlyTrp: 0.948 ± 0.477
3.791GlyTyr: 3.791 ± 3.239
0.0GlyXaa: 0.0 ± 0.0
His
0.948HisAla: 0.948 ± 1.239
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.948HisGlu: 0.948 ± 0.477
0.948HisPhe: 0.948 ± 0.477
0.948HisGly: 0.948 ± 0.477
0.0HisHis: 0.0 ± 0.0
1.896HisIle: 1.896 ± 0.761
0.948HisLys: 0.948 ± 0.477
1.896HisLeu: 1.896 ± 0.761
0.948HisMet: 0.948 ± 0.477
0.0HisAsn: 0.0 ± 0.0
1.896HisPro: 1.896 ± 0.761
0.0HisGln: 0.0 ± 0.0
0.948HisArg: 0.948 ± 0.477
1.896HisSer: 1.896 ± 0.761
1.896HisThr: 1.896 ± 0.955
0.948HisVal: 0.948 ± 0.477
0.0HisTrp: 0.0 ± 0.0
3.791HisTyr: 3.791 ± 0.194
0.0HisXaa: 0.0 ± 0.0
Ile
4.739IleAla: 4.739 ± 1.045
0.0IleCys: 0.0 ± 0.0
3.791IleAsp: 3.791 ± 0.194
1.896IleGlu: 1.896 ± 0.955
1.896IlePhe: 1.896 ± 0.761
7.583IleGly: 7.583 ± 3.819
0.0IleHis: 0.0 ± 0.0
4.739IleIle: 4.739 ± 1.045
2.844IleLys: 2.844 ± 1.432
2.844IleLeu: 2.844 ± 3.716
3.791IleMet: 3.791 ± 0.194
6.635IleAsn: 6.635 ± 0.09
0.0IlePro: 0.0 ± 0.0
1.896IleGln: 1.896 ± 0.955
0.948IleArg: 0.948 ± 0.477
4.739IleSer: 4.739 ± 2.387
8.531IleThr: 8.531 ± 0.865
3.791IleVal: 3.791 ± 0.194
0.948IleTrp: 0.948 ± 1.239
1.896IleTyr: 1.896 ± 0.955
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.948LysCys: 0.948 ± 0.477
1.896LysAsp: 1.896 ± 0.955
1.896LysGlu: 1.896 ± 0.955
3.791LysPhe: 3.791 ± 0.194
1.896LysGly: 1.896 ± 0.761
0.948LysHis: 0.948 ± 0.477
1.896LysIle: 1.896 ± 0.955
5.687LysLys: 5.687 ± 1.148
4.739LysLeu: 4.739 ± 1.045
2.844LysMet: 2.844 ± 0.284
3.791LysAsn: 3.791 ± 1.522
3.791LysPro: 3.791 ± 0.194
3.791LysGln: 3.791 ± 0.194
2.844LysArg: 2.844 ± 1.432
4.739LysSer: 4.739 ± 0.671
2.844LysThr: 2.844 ± 0.284
2.844LysVal: 2.844 ± 1.432
0.0LysTrp: 0.0 ± 0.0
2.844LysTyr: 2.844 ± 2.0
0.0LysXaa: 0.0 ± 0.0
Leu
1.896LeuAla: 1.896 ± 0.761
0.948LeuCys: 0.948 ± 1.239
2.844LeuAsp: 2.844 ± 1.432
1.896LeuGlu: 1.896 ± 0.955
3.791LeuPhe: 3.791 ± 1.91
4.739LeuGly: 4.739 ± 0.671
0.948LeuHis: 0.948 ± 0.477
4.739LeuIle: 4.739 ± 1.045
4.739LeuLys: 4.739 ± 4.477
13.27LeuLeu: 13.27 ± 1.897
3.791LeuMet: 3.791 ± 1.522
7.583LeuAsn: 7.583 ± 3.045
6.635LeuPro: 6.635 ± 1.806
2.844LeuGln: 2.844 ± 1.432
4.739LeuArg: 4.739 ± 0.671
8.531LeuSer: 8.531 ± 2.581
2.844LeuThr: 2.844 ± 0.284
7.583LeuVal: 7.583 ± 3.045
1.896LeuTrp: 1.896 ± 0.955
9.479LeuTyr: 9.479 ± 0.374
0.0LeuXaa: 0.0 ± 0.0
Met
1.896MetAla: 1.896 ± 0.955
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.844MetGlu: 2.844 ± 1.432
0.948MetPhe: 0.948 ± 0.477
1.896MetGly: 1.896 ± 0.955
0.948MetHis: 0.948 ± 1.239
0.948MetIle: 0.948 ± 0.477
1.896MetLys: 1.896 ± 0.761
1.896MetLeu: 1.896 ± 0.955
0.948MetMet: 0.948 ± 1.239
3.791MetAsn: 3.791 ± 1.522
0.948MetPro: 0.948 ± 1.239
1.896MetGln: 1.896 ± 0.761
0.0MetArg: 0.0 ± 0.0
4.739MetSer: 4.739 ± 2.761
0.948MetThr: 0.948 ± 0.477
1.896MetVal: 1.896 ± 0.761
0.0MetTrp: 0.0 ± 0.0
0.948MetTyr: 0.948 ± 1.239
0.0MetXaa: 0.0 ± 0.0
Asn
4.739AsnAla: 4.739 ± 1.045
1.896AsnCys: 1.896 ± 2.477
0.0AsnAsp: 0.0 ± 0.0
0.948AsnGlu: 0.948 ± 0.477
2.844AsnPhe: 2.844 ± 0.284
5.687AsnGly: 5.687 ± 0.568
1.896AsnHis: 1.896 ± 2.477
5.687AsnIle: 5.687 ± 1.148
2.844AsnLys: 2.844 ± 1.432
4.739AsnLeu: 4.739 ± 0.671
0.0AsnMet: 0.0 ± 0.0
13.27AsnAsn: 13.27 ± 4.968
4.739AsnPro: 4.739 ± 0.671
3.791AsnGln: 3.791 ± 1.522
1.896AsnArg: 1.896 ± 0.955
5.687AsnSer: 5.687 ± 0.568
11.374AsnThr: 11.374 ± 1.135
1.896AsnVal: 1.896 ± 0.761
0.0AsnTrp: 0.0 ± 0.0
3.791AsnTyr: 3.791 ± 1.522
0.0AsnXaa: 0.0 ± 0.0
Pro
1.896ProAla: 1.896 ± 0.761
0.0ProCys: 0.0 ± 0.0
2.844ProAsp: 2.844 ± 2.0
1.896ProGlu: 1.896 ± 0.955
0.948ProPhe: 0.948 ± 0.477
0.948ProGly: 0.948 ± 0.477
0.948ProHis: 0.948 ± 0.477
2.844ProIle: 2.844 ± 0.284
1.896ProLys: 1.896 ± 0.955
3.791ProLeu: 3.791 ± 1.522
0.948ProMet: 0.948 ± 1.239
2.844ProAsn: 2.844 ± 0.284
2.844ProPro: 2.844 ± 0.284
0.0ProGln: 0.0 ± 0.0
0.948ProArg: 0.948 ± 0.477
3.791ProSer: 3.791 ± 1.91
3.791ProThr: 3.791 ± 1.522
3.791ProVal: 3.791 ± 0.194
0.948ProTrp: 0.948 ± 0.477
0.948ProTyr: 0.948 ± 1.239
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.948GlnCys: 0.948 ± 1.239
1.896GlnAsp: 1.896 ± 0.761
0.0GlnGlu: 0.0 ± 0.0
3.791GlnPhe: 3.791 ± 1.91
1.896GlnGly: 1.896 ± 0.955
0.948GlnHis: 0.948 ± 1.239
6.635GlnIle: 6.635 ± 0.09
1.896GlnLys: 1.896 ± 0.761
5.687GlnLeu: 5.687 ± 0.568
0.0GlnMet: 0.0 ± 0.0
6.635GlnAsn: 6.635 ± 1.806
0.0GlnPro: 0.0 ± 0.0
3.791GlnGln: 3.791 ± 0.194
0.0GlnArg: 0.0 ± 0.0
1.896GlnSer: 1.896 ± 0.761
2.844GlnThr: 2.844 ± 1.432
0.948GlnVal: 0.948 ± 0.477
0.0GlnTrp: 0.0 ± 0.0
5.687GlnTyr: 5.687 ± 2.864
0.0GlnXaa: 0.0 ± 0.0
Arg
1.896ArgAla: 1.896 ± 0.761
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
2.844ArgGlu: 2.844 ± 1.432
0.0ArgPhe: 0.0 ± 0.0
0.948ArgGly: 0.948 ± 0.477
0.948ArgHis: 0.948 ± 0.477
0.948ArgIle: 0.948 ± 0.477
0.948ArgLys: 0.948 ± 0.477
4.739ArgLeu: 4.739 ± 0.671
2.844ArgMet: 2.844 ± 0.284
5.687ArgAsn: 5.687 ± 0.568
0.0ArgPro: 0.0 ± 0.0
1.896ArgGln: 1.896 ± 0.955
0.948ArgArg: 0.948 ± 0.477
1.896ArgSer: 1.896 ± 2.477
2.844ArgThr: 2.844 ± 1.432
1.896ArgVal: 1.896 ± 0.761
0.0ArgTrp: 0.0 ± 0.0
2.844ArgTyr: 2.844 ± 1.432
0.0ArgXaa: 0.0 ± 0.0
Ser
3.791SerAla: 3.791 ± 1.522
0.948SerCys: 0.948 ± 0.477
1.896SerAsp: 1.896 ± 0.955
0.948SerGlu: 0.948 ± 0.477
3.791SerPhe: 3.791 ± 1.91
7.583SerGly: 7.583 ± 1.329
0.948SerHis: 0.948 ± 1.239
5.687SerIle: 5.687 ± 2.864
2.844SerLys: 2.844 ± 0.284
8.531SerLeu: 8.531 ± 2.568
2.844SerMet: 2.844 ± 2.0
4.739SerAsn: 4.739 ± 1.045
2.844SerPro: 2.844 ± 2.0
4.739SerGln: 4.739 ± 2.387
1.896SerArg: 1.896 ± 0.761
8.531SerSer: 8.531 ± 0.852
8.531SerThr: 8.531 ± 0.865
4.739SerVal: 4.739 ± 2.761
0.0SerTrp: 0.0 ± 0.0
2.844SerTyr: 2.844 ± 2.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.791ThrAla: 3.791 ± 3.239
0.948ThrCys: 0.948 ± 0.477
6.635ThrAsp: 6.635 ± 1.626
1.896ThrGlu: 1.896 ± 2.477
2.844ThrPhe: 2.844 ± 0.284
8.531ThrGly: 8.531 ± 0.865
0.0ThrHis: 0.0 ± 0.0
3.791ThrIle: 3.791 ± 0.194
5.687ThrLys: 5.687 ± 2.284
3.791ThrLeu: 3.791 ± 1.91
2.844ThrMet: 2.844 ± 0.619
3.791ThrAsn: 3.791 ± 0.194
4.739ThrPro: 4.739 ± 0.671
3.791ThrGln: 3.791 ± 1.522
4.739ThrArg: 4.739 ± 0.671
4.739ThrSer: 4.739 ± 2.387
7.583ThrThr: 7.583 ± 1.329
7.583ThrVal: 7.583 ± 2.103
0.0ThrTrp: 0.0 ± 0.0
0.948ThrTyr: 0.948 ± 0.477
0.0ThrXaa: 0.0 ± 0.0
Val
5.687ValAla: 5.687 ± 2.284
0.948ValCys: 0.948 ± 0.477
0.0ValAsp: 0.0 ± 0.0
2.844ValGlu: 2.844 ± 0.284
3.791ValPhe: 3.791 ± 0.194
2.844ValGly: 2.844 ± 0.284
0.948ValHis: 0.948 ± 1.239
5.687ValIle: 5.687 ± 0.568
0.948ValLys: 0.948 ± 0.477
6.635ValLeu: 6.635 ± 1.626
0.0ValMet: 0.0 ± 0.699
2.844ValAsn: 2.844 ± 0.284
1.896ValPro: 1.896 ± 0.955
2.844ValGln: 2.844 ± 2.0
4.739ValArg: 4.739 ± 2.387
3.791ValSer: 3.791 ± 1.522
2.844ValThr: 2.844 ± 1.432
7.583ValVal: 7.583 ± 2.103
0.948ValTrp: 0.948 ± 0.477
5.687ValTyr: 5.687 ± 0.568
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.948TrpCys: 0.948 ± 0.477
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.948TrpPhe: 0.948 ± 0.477
0.0TrpGly: 0.0 ± 0.0
0.948TrpHis: 0.948 ± 0.477
0.948TrpIle: 0.948 ± 1.239
0.0TrpLys: 0.0 ± 0.0
1.896TrpLeu: 1.896 ± 0.955
0.0TrpMet: 0.0 ± 0.0
0.948TrpAsn: 0.948 ± 1.239
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.948TrpArg: 0.948 ± 1.239
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.844TyrAla: 2.844 ± 0.284
0.0TyrCys: 0.0 ± 0.0
5.687TyrAsp: 5.687 ± 2.284
3.791TyrGlu: 3.791 ± 0.194
0.0TyrPhe: 0.0 ± 0.0
1.896TyrGly: 1.896 ± 0.761
1.896TyrHis: 1.896 ± 0.955
2.844TyrIle: 2.844 ± 1.432
5.687TyrLys: 5.687 ± 0.568
5.687TyrLeu: 5.687 ± 0.568
1.896TyrMet: 1.896 ± 0.761
3.791TyrAsn: 3.791 ± 0.194
1.896TyrPro: 1.896 ± 0.761
5.687TyrGln: 5.687 ± 0.568
1.896TyrArg: 1.896 ± 0.955
3.791TyrSer: 3.791 ± 0.194
1.896TyrThr: 1.896 ± 0.761
2.844TyrVal: 2.844 ± 1.432
0.948TyrTrp: 0.948 ± 1.239
0.948TyrTyr: 0.948 ± 1.239
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1056 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski