Amino acid dipepetide frequency for Sphingobacterium paucimobilis HER1398

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.261AlaAla: 5.261 ± 0.072	0.618AlaCys: 0.618 ± 0.019	3.988AlaAsp: 3.988 ± 0.052	4.129AlaGlu: 4.129 ± 0.056	3.213AlaPhe: 3.213 ± 0.054	4.636AlaGly: 4.636 ± 0.072	1.212AlaHis: 1.212 ± 0.032	5.29AlaIle: 5.29 ± 0.07	4.54AlaLys: 4.54 ± 0.068	7.052AlaLeu: 7.052 ± 0.086	1.638AlaMet: 1.638 ± 0.036	3.57AlaAsn: 3.57 ± 0.056	2.167AlaPro: 2.167 ± 0.044	2.876AlaGln: 2.876 ± 0.041	2.531AlaArg: 2.531 ± 0.042	4.594AlaSer: 4.594 ± 0.06	3.908AlaThr: 3.908 ± 0.066	4.859AlaVal: 4.859 ± 0.069	0.724AlaTrp: 0.724 ± 0.02	3.02AlaTyr: 3.02 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.431CysAla: 0.431 ± 0.018	0.103CysCys: 0.103 ± 0.008	0.371CysAsp: 0.371 ± 0.016	0.36CysGlu: 0.36 ± 0.015	0.371CysPhe: 0.371 ± 0.015	0.561CysGly: 0.561 ± 0.021	0.169CysHis: 0.169 ± 0.012	0.535CysIle: 0.535 ± 0.022	0.39CysLys: 0.39 ± 0.017	0.641CysLeu: 0.641 ± 0.023	0.155CysMet: 0.155 ± 0.012	0.319CysAsn: 0.319 ± 0.016	0.283CysPro: 0.283 ± 0.016	0.235CysGln: 0.235 ± 0.013	0.285CysArg: 0.285 ± 0.015	0.51CysSer: 0.51 ± 0.02	0.413CysThr: 0.413 ± 0.018	0.42CysVal: 0.42 ± 0.02	0.07CysTrp: 0.07 ± 0.007	0.29CysTyr: 0.29 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.732AspAla: 3.732 ± 0.051	0.324AspCys: 0.324 ± 0.015	2.565AspAsp: 2.565 ± 0.051	3.471AspGlu: 3.471 ± 0.055	3.3AspPhe: 3.3 ± 0.058	3.922AspGly: 3.922 ± 0.06	0.983AspHis: 0.983 ± 0.027	4.498AspIle: 4.498 ± 0.051	4.109AspLys: 4.109 ± 0.063	5.399AspLeu: 5.399 ± 0.069	1.333AspMet: 1.333 ± 0.031	2.925AspAsn: 2.925 ± 0.049	2.108AspPro: 2.108 ± 0.043	2.0AspGln: 2.0 ± 0.032	2.738AspArg: 2.738 ± 0.046	3.157AspSer: 3.157 ± 0.053	2.601AspThr: 2.601 ± 0.041	3.578AspVal: 3.578 ± 0.06	0.791AspTrp: 0.791 ± 0.025	2.825AspTyr: 2.825 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	4.425GluAla: 4.425 ± 0.061	0.298GluCys: 0.298 ± 0.015	3.3GluAsp: 3.3 ± 0.054	4.613GluGlu: 4.613 ± 0.071	2.374GluPhe: 2.374 ± 0.04	4.049GluGly: 4.049 ± 0.055	1.18GluHis: 1.18 ± 0.029	4.666GluIle: 4.666 ± 0.058	4.731GluLys: 4.731 ± 0.063	6.11GluLeu: 6.11 ± 0.073	1.469GluMet: 1.469 ± 0.036	3.504GluAsn: 3.504 ± 0.058	1.517GluPro: 1.517 ± 0.037	2.69GluGln: 2.69 ± 0.044	3.006GluArg: 3.006 ± 0.05	3.377GluSer: 3.377 ± 0.047	2.91GluThr: 2.91 ± 0.046	4.331GluVal: 4.331 ± 0.057	0.685GluTrp: 0.685 ± 0.02	2.22GluTyr: 2.22 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.121PheAla: 3.121 ± 0.043	0.393PheCys: 0.393 ± 0.016	3.061PheAsp: 3.061 ± 0.049	3.047PheGlu: 3.047 ± 0.048	2.496PhePhe: 2.496 ± 0.049	3.457PheGly: 3.457 ± 0.058	0.803PheHis: 0.803 ± 0.025	3.091PheIle: 3.091 ± 0.055	3.008PheLys: 3.008 ± 0.053	4.362PheLeu: 4.362 ± 0.076	1.141PheMet: 1.141 ± 0.031	2.747PheAsn: 2.747 ± 0.045	1.667PhePro: 1.667 ± 0.034	1.514PheGln: 1.514 ± 0.029	1.929PheArg: 1.929 ± 0.037	3.609PheSer: 3.609 ± 0.048	2.698PheThr: 2.698 ± 0.047	3.078PheVal: 3.078 ± 0.047	0.57PheTrp: 0.57 ± 0.023	2.029PheTyr: 2.029 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.693GlyAla: 4.693 ± 0.07	0.533GlyCys: 0.533 ± 0.022	3.526GlyAsp: 3.526 ± 0.048	3.61GlyGlu: 3.61 ± 0.05	3.417GlyPhe: 3.417 ± 0.06	4.734GlyGly: 4.734 ± 0.088	1.198GlyHis: 1.198 ± 0.027	5.204GlyIle: 5.204 ± 0.061	4.833GlyLys: 4.833 ± 0.066	6.112GlyLeu: 6.112 ± 0.073	1.765GlyMet: 1.765 ± 0.036	3.624GlyAsn: 3.624 ± 0.066	1.446GlyPro: 1.446 ± 0.035	2.526GlyGln: 2.526 ± 0.046	2.868GlyArg: 2.868 ± 0.048	4.395GlySer: 4.395 ± 0.068	4.212GlyThr: 4.212 ± 0.076	4.689GlyVal: 4.689 ± 0.068	0.848GlyTrp: 0.848 ± 0.026	3.267GlyTyr: 3.267 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.166HisAla: 1.166 ± 0.032	0.171HisCys: 0.171 ± 0.01	0.875HisAsp: 0.875 ± 0.027	0.956HisGlu: 0.956 ± 0.027	1.061HisPhe: 1.061 ± 0.029	1.137HisGly: 1.137 ± 0.027	0.462HisHis: 0.462 ± 0.022	1.542HisIle: 1.542 ± 0.036	1.037HisLys: 1.037 ± 0.025	1.887HisLeu: 1.887 ± 0.042	0.418HisMet: 0.418 ± 0.018	0.944HisAsn: 0.944 ± 0.027	0.873HisPro: 0.873 ± 0.025	0.772HisGln: 0.772 ± 0.024	0.856HisArg: 0.856 ± 0.023	1.095HisSer: 1.095 ± 0.025	1.04HisThr: 1.04 ± 0.026	1.115HisVal: 1.115 ± 0.025	0.246HisTrp: 0.246 ± 0.013	0.883HisTyr: 0.883 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.723IleAla: 5.723 ± 0.066	0.589IleCys: 0.589 ± 0.023	4.561IleAsp: 4.561 ± 0.059	4.533IleGlu: 4.533 ± 0.06	2.904IlePhe: 2.904 ± 0.05	4.991IleGly: 4.991 ± 0.067	1.37IleHis: 1.37 ± 0.028	4.627IleIle: 4.627 ± 0.071	4.671IleLys: 4.671 ± 0.061	6.425IleLeu: 6.425 ± 0.084	1.357IleMet: 1.357 ± 0.036	3.865IleAsn: 3.865 ± 0.053	3.127IlePro: 3.127 ± 0.048	2.781IleGln: 2.781 ± 0.045	3.151IleArg: 3.151 ± 0.057	4.934IleSer: 4.934 ± 0.059	4.083IleThr: 4.083 ± 0.058	4.589IleVal: 4.589 ± 0.059	0.73IleTrp: 0.73 ± 0.022	2.602IleTyr: 2.602 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.613LysAla: 4.613 ± 0.065	0.273LysCys: 0.273 ± 0.014	4.356LysAsp: 4.356 ± 0.054	5.41LysGlu: 5.41 ± 0.075	2.351LysPhe: 2.351 ± 0.045	4.592LysGly: 4.592 ± 0.061	1.209LysHis: 1.209 ± 0.029	4.628LysIle: 4.628 ± 0.058	5.093LysLys: 5.093 ± 0.07	5.736LysLeu: 5.736 ± 0.066	1.826LysMet: 1.826 ± 0.038	3.934LysAsn: 3.934 ± 0.051	2.277LysPro: 2.277 ± 0.041	2.602LysGln: 2.602 ± 0.049	2.943LysArg: 2.943 ± 0.046	4.197LysSer: 4.197 ± 0.058	3.743LysThr: 3.743 ± 0.048	4.397LysVal: 4.397 ± 0.061	0.738LysTrp: 0.738 ± 0.023	2.804LysTyr: 2.804 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	6.659LeuAla: 6.659 ± 0.075	0.763LeuCys: 0.763 ± 0.025	5.422LeuAsp: 5.422 ± 0.064	5.743LeuGlu: 5.743 ± 0.075	4.822LeuPhe: 4.822 ± 0.07	6.153LeuGly: 6.153 ± 0.068	1.84LeuHis: 1.84 ± 0.037	6.253LeuIle: 6.253 ± 0.085	6.728LeuLys: 6.728 ± 0.075	9.828LeuLeu: 9.828 ± 0.129	2.108LeuMet: 2.108 ± 0.04	5.068LeuAsn: 5.068 ± 0.07	3.822LeuPro: 3.822 ± 0.049	3.826LeuGln: 3.826 ± 0.055	4.208LeuArg: 4.208 ± 0.06	7.305LeuSer: 7.305 ± 0.075	5.356LeuThr: 5.356 ± 0.069	5.628LeuVal: 5.628 ± 0.065	0.956LeuTrp: 0.956 ± 0.027	3.718LeuTyr: 3.718 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	1.641MetAla: 1.641 ± 0.029	0.119MetCys: 0.119 ± 0.008	1.397MetAsp: 1.397 ± 0.031	1.465MetGlu: 1.465 ± 0.034	0.819MetPhe: 0.819 ± 0.026	1.581MetGly: 1.581 ± 0.037	0.396MetHis: 0.396 ± 0.017	1.424MetIle: 1.424 ± 0.033	1.868MetLys: 1.868 ± 0.037	2.204MetLeu: 2.204 ± 0.042	0.607MetMet: 0.607 ± 0.022	1.32MetAsn: 1.32 ± 0.03	0.958MetPro: 0.958 ± 0.028	0.933MetGln: 0.933 ± 0.025	1.075MetArg: 1.075 ± 0.029	1.471MetSer: 1.471 ± 0.031	1.247MetThr: 1.247 ± 0.03	1.438MetVal: 1.438 ± 0.033	0.181MetTrp: 0.181 ± 0.011	0.813MetTyr: 0.813 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.589AsnAla: 3.589 ± 0.049	0.282AsnCys: 0.282 ± 0.015	2.642AsnAsp: 2.642 ± 0.043	2.96AsnGlu: 2.96 ± 0.05	2.431AsnPhe: 2.431 ± 0.045	3.774AsnGly: 3.774 ± 0.062	0.932AsnHis: 0.932 ± 0.024	4.125AsnIle: 4.125 ± 0.058	3.737AsnLys: 3.737 ± 0.052	4.906AsnLeu: 4.906 ± 0.067	1.278AsnMet: 1.278 ± 0.03	3.123AsnAsn: 3.123 ± 0.058	2.549AsnPro: 2.549 ± 0.053	2.041AsnGln: 2.041 ± 0.037	2.584AsnArg: 2.584 ± 0.043	3.498AsnSer: 3.498 ± 0.057	3.411AsnThr: 3.411 ± 0.054	3.238AsnVal: 3.238 ± 0.062	0.712AsnTrp: 0.712 ± 0.021	2.535AsnTyr: 2.535 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	2.327ProAla: 2.327 ± 0.048	0.232ProCys: 0.232 ± 0.012	2.156ProAsp: 2.156 ± 0.039	2.524ProGlu: 2.524 ± 0.04	1.796ProPhe: 1.796 ± 0.038	2.162ProGly: 2.162 ± 0.046	0.686ProHis: 0.686 ± 0.023	2.732ProIle: 2.732 ± 0.042	2.094ProLys: 2.094 ± 0.043	3.338ProLeu: 3.338 ± 0.051	0.756ProMet: 0.756 ± 0.026	1.978ProAsn: 1.978 ± 0.04	0.841ProPro: 0.841 ± 0.023	1.344ProGln: 1.344 ± 0.033	1.249ProArg: 1.249 ± 0.03	2.449ProSer: 2.449 ± 0.047	2.136ProThr: 2.136 ± 0.044	2.531ProVal: 2.531 ± 0.045	0.381ProTrp: 0.381 ± 0.015	1.567ProTyr: 1.567 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.701GlnAla: 2.701 ± 0.043	0.185GlnCys: 0.185 ± 0.011	1.943GlnAsp: 1.943 ± 0.036	2.639GlnGlu: 2.639 ± 0.05	1.614GlnPhe: 1.614 ± 0.033	2.31GlnGly: 2.31 ± 0.039	0.893GlnHis: 0.893 ± 0.025	2.636GlnIle: 2.636 ± 0.038	2.58GlnLys: 2.58 ± 0.046	4.045GlnLeu: 4.045 ± 0.06	0.851GlnMet: 0.851 ± 0.025	1.959GlnAsn: 1.959 ± 0.036	1.169GlnPro: 1.169 ± 0.031	2.158GlnGln: 2.158 ± 0.045	1.838GlnArg: 1.838 ± 0.033	2.266GlnSer: 2.266 ± 0.043	2.02GlnThr: 2.02 ± 0.037	2.53GlnVal: 2.53 ± 0.036	0.445GlnTrp: 0.445 ± 0.02	1.672GlnTyr: 1.672 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.682ArgAla: 2.682 ± 0.049	0.212ArgCys: 0.212 ± 0.013	2.246ArgAsp: 2.246 ± 0.037	2.624ArgGlu: 2.624 ± 0.042	2.3ArgPhe: 2.3 ± 0.038	2.481ArgGly: 2.481 ± 0.045	0.809ArgHis: 0.809 ± 0.021	3.421ArgIle: 3.421 ± 0.052	2.954ArgLys: 2.954 ± 0.044	4.322ArgLeu: 4.322 ± 0.052	1.18ArgMet: 1.18 ± 0.029	2.395ArgAsn: 2.395 ± 0.038	1.423ArgPro: 1.423 ± 0.033	1.601ArgGln: 1.601 ± 0.035	1.88ArgArg: 1.88 ± 0.04	2.613ArgSer: 2.613 ± 0.048	2.283ArgThr: 2.283 ± 0.043	2.758ArgVal: 2.758 ± 0.044	0.628ArgTrp: 0.628 ± 0.02	2.28ArgTyr: 2.28 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	4.402SerAla: 4.402 ± 0.056	0.61SerCys: 0.61 ± 0.02	3.454SerAsp: 3.454 ± 0.045	3.396SerGlu: 3.396 ± 0.054	3.743SerPhe: 3.743 ± 0.046	4.644SerGly: 4.644 ± 0.063	1.119SerHis: 1.119 ± 0.029	4.975SerIle: 4.975 ± 0.066	4.266SerLys: 4.266 ± 0.057	6.624SerLeu: 6.624 ± 0.065	1.379SerMet: 1.379 ± 0.03	3.528SerAsn: 3.528 ± 0.06	2.349SerPro: 2.349 ± 0.046	2.091SerGln: 2.091 ± 0.038	2.692SerArg: 2.692 ± 0.047	4.766SerSer: 4.766 ± 0.078	3.902SerThr: 3.902 ± 0.059	4.243SerVal: 4.243 ± 0.055	0.84SerTrp: 0.84 ± 0.026	3.17SerTyr: 3.17 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.372ThrAla: 4.372 ± 0.072	0.296ThrCys: 0.296 ± 0.015	3.271ThrAsp: 3.271 ± 0.044	3.046ThrGlu: 3.046 ± 0.043	2.72ThrPhe: 2.72 ± 0.048	4.298ThrGly: 4.298 ± 0.073	0.993ThrHis: 0.993 ± 0.027	4.097ThrIle: 4.097 ± 0.06	3.412ThrLys: 3.412 ± 0.056	5.507ThrLeu: 5.507 ± 0.066	1.062ThrMet: 1.062 ± 0.028	2.779ThrAsn: 2.779 ± 0.053	2.335ThrPro: 2.335 ± 0.047	1.859ThrGln: 1.859 ± 0.036	1.829ThrArg: 1.829 ± 0.038	3.592ThrSer: 3.592 ± 0.048	3.199ThrThr: 3.199 ± 0.063	3.998ThrVal: 3.998 ± 0.077	0.628ThrTrp: 0.628 ± 0.023	2.508ThrTyr: 2.508 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	4.537ValAla: 4.537 ± 0.065	0.493ValCys: 0.493 ± 0.018	4.014ValAsp: 4.014 ± 0.062	3.931ValGlu: 3.931 ± 0.056	3.257ValPhe: 3.257 ± 0.048	4.241ValGly: 4.241 ± 0.062	1.183ValHis: 1.183 ± 0.029	4.308ValIle: 4.308 ± 0.055	4.133ValLys: 4.133 ± 0.053	6.475ValLeu: 6.475 ± 0.078	1.378ValMet: 1.378 ± 0.034	3.445ValAsn: 3.445 ± 0.055	2.406ValPro: 2.406 ± 0.042	2.335ValGln: 2.335 ± 0.043	2.816ValArg: 2.816 ± 0.052	4.703ValSer: 4.703 ± 0.066	3.458ValThr: 3.458 ± 0.071	4.588ValVal: 4.588 ± 0.069	0.703ValTrp: 0.703 ± 0.024	2.623ValTyr: 2.623 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.74TrpAla: 0.74 ± 0.025	0.121TrpCys: 0.121 ± 0.009	0.658TrpAsp: 0.658 ± 0.021	0.694TrpGlu: 0.694 ± 0.023	0.502TrpPhe: 0.502 ± 0.02	0.805TrpGly: 0.805 ± 0.024	0.226TrpHis: 0.226 ± 0.013	0.763TrpIle: 0.763 ± 0.024	0.834TrpLys: 0.834 ± 0.022	1.094TrpLeu: 1.094 ± 0.031	0.337TrpMet: 0.337 ± 0.015	0.722TrpAsn: 0.722 ± 0.025	0.265TrpPro: 0.265 ± 0.012	0.505TrpGln: 0.505 ± 0.02	0.551TrpArg: 0.551 ± 0.021	0.769TrpSer: 0.769 ± 0.025	0.665TrpThr: 0.665 ± 0.023	0.647TrpVal: 0.647 ± 0.023	0.144TrpTrp: 0.144 ± 0.011	0.487TrpTyr: 0.487 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.01TyrAla: 3.01 ± 0.05	0.297TyrCys: 0.297 ± 0.014	2.553TyrAsp: 2.553 ± 0.043	2.304TyrGlu: 2.304 ± 0.038	2.329TyrPhe: 2.329 ± 0.044	2.974TyrGly: 2.974 ± 0.041	0.873TyrHis: 0.873 ± 0.027	2.799TyrIle: 2.799 ± 0.044	2.704TyrLys: 2.704 ± 0.047	4.141TyrLeu: 4.141 ± 0.062	0.92TyrMet: 0.92 ± 0.024	2.598TyrAsn: 2.598 ± 0.056	1.694TyrPro: 1.694 ± 0.035	1.766TyrGln: 1.766 ± 0.039	2.067TyrArg: 2.067 ± 0.039	2.889TyrSer: 2.889 ± 0.048	2.517TyrThr: 2.517 ± 0.049	2.37TyrVal: 2.37 ± 0.042	0.51TyrTrp: 0.51 ± 0.019	2.052TyrTyr: 2.052 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4220 proteins (1481620 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---