Amino acid dipepetide frequency for Struthio camelus australis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.407AlaAla: 5.407 ± 0.056	1.303AlaCys: 1.303 ± 0.019	2.965AlaAsp: 2.965 ± 0.023	4.51AlaGlu: 4.51 ± 0.041	2.542AlaPhe: 2.542 ± 0.025	3.687AlaGly: 3.687 ± 0.035	1.339AlaHis: 1.339 ± 0.016	3.128AlaIle: 3.128 ± 0.025	3.704AlaLys: 3.704 ± 0.03	6.289AlaLeu: 6.289 ± 0.046	1.456AlaMet: 1.456 ± 0.017	2.276AlaAsn: 2.276 ± 0.023	2.751AlaPro: 2.751 ± 0.035	2.666AlaGln: 2.666 ± 0.029	2.885AlaArg: 2.885 ± 0.028	5.116AlaSer: 5.116 ± 0.035	3.296AlaThr: 3.296 ± 0.027	4.78AlaVal: 4.78 ± 0.036	0.686AlaTrp: 0.686 ± 0.011	1.635AlaTyr: 1.635 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.161CysAla: 1.161 ± 0.021	0.628CysCys: 0.628 ± 0.014	1.05CysAsp: 1.05 ± 0.021	1.284CysGlu: 1.284 ± 0.022	0.909CysPhe: 0.909 ± 0.013	1.401CysGly: 1.401 ± 0.022	0.611CysHis: 0.611 ± 0.013	1.176CysIle: 1.176 ± 0.021	1.341CysLys: 1.341 ± 0.018	2.157CysLeu: 2.157 ± 0.023	0.451CysMet: 0.451 ± 0.011	0.92CysAsn: 0.92 ± 0.015	1.206CysPro: 1.206 ± 0.027	1.049CysGln: 1.049 ± 0.017	1.171CysArg: 1.171 ± 0.015	1.971CysSer: 1.971 ± 0.025	1.171CysThr: 1.171 ± 0.021	1.339CysVal: 1.339 ± 0.023	0.279CysTrp: 0.279 ± 0.008	0.671CysTyr: 0.671 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	2.827AspAla: 2.827 ± 0.025	1.098AspCys: 1.098 ± 0.02	2.831AspAsp: 2.831 ± 0.027	3.638AspGlu: 3.638 ± 0.035	2.241AspPhe: 2.241 ± 0.021	3.166AspGly: 3.166 ± 0.033	1.145AspHis: 1.145 ± 0.016	2.966AspIle: 2.966 ± 0.025	2.816AspLys: 2.816 ± 0.026	5.052AspLeu: 5.052 ± 0.035	1.164AspMet: 1.164 ± 0.015	1.967AspAsn: 1.967 ± 0.02	2.56AspPro: 2.56 ± 0.027	1.83AspGln: 1.83 ± 0.018	2.331AspArg: 2.331 ± 0.021	4.062AspSer: 4.062 ± 0.036	2.452AspThr: 2.452 ± 0.02	3.499AspVal: 3.499 ± 0.024	0.664AspTrp: 0.664 ± 0.012	1.652AspTyr: 1.652 ± 0.018	0.001AspXaa: 0.001 ± 0.0
Glu	4.599GluAla: 4.599 ± 0.039	1.321GluCys: 1.321 ± 0.029	4.524GluAsp: 4.524 ± 0.033	7.845GluGlu: 7.845 ± 0.075	2.202GluPhe: 2.202 ± 0.022	3.73GluGly: 3.73 ± 0.026	1.892GluHis: 1.892 ± 0.019	3.887GluIle: 3.887 ± 0.03	5.751GluLys: 5.751 ± 0.053	6.289GluLeu: 6.289 ± 0.049	1.763GluMet: 1.763 ± 0.019	3.495GluAsn: 3.495 ± 0.027	2.495GluPro: 2.495 ± 0.026	3.177GluGln: 3.177 ± 0.027	3.879GluArg: 3.879 ± 0.036	4.801GluSer: 4.801 ± 0.035	3.543GluThr: 3.543 ± 0.03	4.541GluVal: 4.541 ± 0.031	0.709GluTrp: 0.709 ± 0.011	1.866GluTyr: 1.866 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.15PheAla: 2.15 ± 0.023	0.988PheCys: 0.988 ± 0.015	1.831PheAsp: 1.831 ± 0.021	2.149PheGlu: 2.149 ± 0.019	2.086PhePhe: 2.086 ± 0.025	2.27PheGly: 2.27 ± 0.023	1.412PheHis: 1.412 ± 0.017	2.098PheIle: 2.098 ± 0.021	2.368PheLys: 2.368 ± 0.021	4.192PheLeu: 4.192 ± 0.034	0.775PheMet: 0.775 ± 0.012	1.537PheAsn: 1.537 ± 0.019	1.982PhePro: 1.982 ± 0.02	1.831PheGln: 1.831 ± 0.02	1.899PheArg: 1.899 ± 0.02	3.463PheSer: 3.463 ± 0.03	2.396PheThr: 2.396 ± 0.023	2.333PheVal: 2.333 ± 0.024	0.529PheTrp: 0.529 ± 0.011	1.324PheTyr: 1.324 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	3.309GlyAla: 3.309 ± 0.027	1.207GlyCys: 1.207 ± 0.02	2.859GlyAsp: 2.859 ± 0.027	3.631GlyGlu: 3.631 ± 0.038	2.391GlyPhe: 2.391 ± 0.029	3.708GlyGly: 3.708 ± 0.045	1.592GlyHis: 1.592 ± 0.022	3.086GlyIle: 3.086 ± 0.026	4.0GlyLys: 4.0 ± 0.03	5.042GlyLeu: 5.042 ± 0.04	1.35GlyMet: 1.35 ± 0.019	2.959GlyAsn: 2.959 ± 0.027	2.522GlyPro: 2.522 ± 0.044	2.629GlyGln: 2.629 ± 0.025	3.01GlyArg: 3.01 ± 0.03	4.808GlySer: 4.808 ± 0.039	3.27GlyThr: 3.27 ± 0.027	3.349GlyVal: 3.349 ± 0.03	0.72GlyTrp: 0.72 ± 0.014	1.871GlyTyr: 1.871 ± 0.022	0.001GlyXaa: 0.001 ± 0.0
His	1.307HisAla: 1.307 ± 0.018	0.703HisCys: 0.703 ± 0.013	0.929HisAsp: 0.929 ± 0.014	1.339HisGlu: 1.339 ± 0.016	1.085HisPhe: 1.085 ± 0.016	1.433HisGly: 1.433 ± 0.017	0.815HisHis: 0.815 ± 0.016	1.342HisIle: 1.342 ± 0.018	1.542HisLys: 1.542 ± 0.018	3.173HisLeu: 3.173 ± 0.031	0.564HisMet: 0.564 ± 0.012	0.962HisAsn: 0.962 ± 0.012	1.44HisPro: 1.44 ± 0.02	1.179HisGln: 1.179 ± 0.015	1.763HisArg: 1.763 ± 0.02	2.138HisSer: 2.138 ± 0.026	1.261HisThr: 1.261 ± 0.019	1.536HisVal: 1.536 ± 0.017	0.679HisTrp: 0.679 ± 0.014	0.843HisTyr: 0.843 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.055IleAla: 3.055 ± 0.025	1.218IleCys: 1.218 ± 0.02	2.342IleAsp: 2.342 ± 0.021	2.94IleGlu: 2.94 ± 0.027	2.509IlePhe: 2.509 ± 0.025	2.496IleGly: 2.496 ± 0.023	1.4IleHis: 1.4 ± 0.016	2.767IleIle: 2.767 ± 0.026	3.049IleLys: 3.049 ± 0.026	5.391IleLeu: 5.391 ± 0.035	1.081IleMet: 1.081 ± 0.015	2.204IleAsn: 2.204 ± 0.022	2.839IlePro: 2.839 ± 0.023	2.486IleGln: 2.486 ± 0.024	2.558IleArg: 2.558 ± 0.023	4.116IleSer: 4.116 ± 0.038	2.877IleThr: 2.877 ± 0.025	2.91IleVal: 2.91 ± 0.027	0.574IleTrp: 0.574 ± 0.011	1.601IleTyr: 1.601 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.122LysAla: 4.122 ± 0.035	1.245LysCys: 1.245 ± 0.02	3.478LysAsp: 3.478 ± 0.029	5.667LysGlu: 5.667 ± 0.05	2.238LysPhe: 2.238 ± 0.023	3.377LysGly: 3.377 ± 0.029	1.665LysHis: 1.665 ± 0.017	3.253LysIle: 3.253 ± 0.026	5.514LysLys: 5.514 ± 0.051	6.124LysLeu: 6.124 ± 0.038	1.568LysMet: 1.568 ± 0.017	3.143LysAsn: 3.143 ± 0.026	3.002LysPro: 3.002 ± 0.032	2.984LysGln: 2.984 ± 0.03	3.596LysArg: 3.596 ± 0.03	4.364LysSer: 4.364 ± 0.032	3.669LysThr: 3.669 ± 0.029	3.802LysVal: 3.802 ± 0.027	0.682LysTrp: 0.682 ± 0.01	1.923LysTyr: 1.923 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	6.106LeuAla: 6.106 ± 0.052	2.143LeuCys: 2.143 ± 0.021	5.101LeuAsp: 5.101 ± 0.033	7.438LeuGlu: 7.438 ± 0.052	3.631LeuPhe: 3.631 ± 0.037	5.509LeuGly: 5.509 ± 0.044	2.675LeuHis: 2.675 ± 0.025	4.293LeuIle: 4.293 ± 0.034	6.539LeuLys: 6.539 ± 0.04	10.006LeuLeu: 10.006 ± 0.073	2.096LeuMet: 2.096 ± 0.023	4.599LeuAsn: 4.599 ± 0.033	5.529LeuPro: 5.529 ± 0.038	5.558LeuGln: 5.558 ± 0.051	5.325LeuArg: 5.325 ± 0.041	7.791LeuSer: 7.791 ± 0.05	5.018LeuThr: 5.018 ± 0.031	5.398LeuVal: 5.398 ± 0.037	1.045LeuTrp: 1.045 ± 0.016	2.79LeuTyr: 2.79 ± 0.028	0.001LeuXaa: 0.001 ± 0.0
Met	1.599MetAla: 1.599 ± 0.016	0.426MetCys: 0.426 ± 0.01	1.26MetAsp: 1.26 ± 0.015	1.871MetGlu: 1.871 ± 0.021	0.821MetPhe: 0.821 ± 0.013	1.243MetGly: 1.243 ± 0.017	0.573MetHis: 0.573 ± 0.01	1.002MetIle: 1.002 ± 0.013	1.628MetLys: 1.628 ± 0.018	2.301MetLeu: 2.301 ± 0.023	0.596MetMet: 0.596 ± 0.012	1.0MetAsn: 1.0 ± 0.015	1.026MetPro: 1.026 ± 0.014	1.036MetGln: 1.036 ± 0.016	1.07MetArg: 1.07 ± 0.014	1.541MetSer: 1.541 ± 0.019	1.154MetThr: 1.154 ± 0.014	1.391MetVal: 1.391 ± 0.017	0.252MetTrp: 0.252 ± 0.007	0.65MetTyr: 0.65 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.342AsnAla: 2.342 ± 0.022	0.973AsnCys: 0.973 ± 0.018	1.713AsnAsp: 1.713 ± 0.019	2.61AsnGlu: 2.61 ± 0.025	1.978AsnPhe: 1.978 ± 0.022	3.061AsnGly: 3.061 ± 0.034	1.255AsnHis: 1.255 ± 0.015	2.526AsnIle: 2.526 ± 0.024	2.646AsnLys: 2.646 ± 0.023	4.37AsnLeu: 4.37 ± 0.036	1.335AsnMet: 1.335 ± 0.016	1.872AsnAsn: 1.872 ± 0.026	2.28AsnPro: 2.28 ± 0.021	1.718AsnGln: 1.718 ± 0.017	2.281AsnArg: 2.281 ± 0.02	3.447AsnSer: 3.447 ± 0.034	2.197AsnThr: 2.197 ± 0.021	2.584AsnVal: 2.584 ± 0.027	0.493AsnTrp: 0.493 ± 0.011	1.326AsnTyr: 1.326 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	3.505ProAla: 3.505 ± 0.036	0.994ProCys: 0.994 ± 0.019	2.555ProAsp: 2.555 ± 0.021	3.784ProGlu: 3.784 ± 0.037	1.863ProPhe: 1.863 ± 0.022	3.404ProGly: 3.404 ± 0.049	1.212ProHis: 1.212 ± 0.015	1.942ProIle: 1.942 ± 0.02	2.724ProLys: 2.724 ± 0.026	4.578ProLeu: 4.578 ± 0.034	0.924ProMet: 0.924 ± 0.015	1.9ProAsn: 1.9 ± 0.019	4.062ProPro: 4.062 ± 0.069	2.263ProGln: 2.263 ± 0.028	2.731ProArg: 2.731 ± 0.027	5.035ProSer: 5.035 ± 0.037	2.568ProThr: 2.568 ± 0.026	3.723ProVal: 3.723 ± 0.031	0.538ProTrp: 0.538 ± 0.011	1.419ProTyr: 1.419 ± 0.017	0.001ProXaa: 0.001 ± 0.0
Gln	2.976GlnAla: 2.976 ± 0.03	0.973GlnCys: 0.973 ± 0.018	2.184GlnAsp: 2.184 ± 0.022	3.643GlnGlu: 3.643 ± 0.031	1.565GlnPhe: 1.565 ± 0.017	2.328GlnGly: 2.328 ± 0.026	1.249GlnHis: 1.249 ± 0.019	2.266GlnIle: 2.266 ± 0.021	3.384GlnLys: 3.384 ± 0.027	4.559GlnLeu: 4.559 ± 0.039	1.092GlnMet: 1.092 ± 0.015	2.053GlnAsn: 2.053 ± 0.024	2.265GlnPro: 2.265 ± 0.026	2.996GlnGln: 2.996 ± 0.049	2.604GlnArg: 2.604 ± 0.022	3.173GlnSer: 3.173 ± 0.027	2.35GlnThr: 2.35 ± 0.022	2.681GlnVal: 2.681 ± 0.025	0.526GlnTrp: 0.526 ± 0.01	1.324GlnTyr: 1.324 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	2.962ArgAla: 2.962 ± 0.023	1.082ArgCys: 1.082 ± 0.02	2.568ArgAsp: 2.568 ± 0.023	3.967ArgGlu: 3.967 ± 0.033	1.845ArgPhe: 1.845 ± 0.019	2.797ArgGly: 2.797 ± 0.035	1.371ArgHis: 1.371 ± 0.017	2.597ArgIle: 2.597 ± 0.027	4.427ArgLys: 4.427 ± 0.033	5.431ArgLeu: 5.431 ± 0.035	1.142ArgMet: 1.142 ± 0.014	2.301ArgAsn: 2.301 ± 0.019	2.382ArgPro: 2.382 ± 0.027	2.475ArgGln: 2.475 ± 0.025	3.574ArgArg: 3.574 ± 0.032	3.882ArgSer: 3.882 ± 0.042	2.683ArgThr: 2.683 ± 0.025	3.188ArgVal: 3.188 ± 0.022	0.633ArgTrp: 0.633 ± 0.012	1.55ArgTyr: 1.55 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	5.014SerAla: 5.014 ± 0.032	1.803SerCys: 1.803 ± 0.023	3.97SerAsp: 3.97 ± 0.036	5.077SerGlu: 5.077 ± 0.038	3.094SerPhe: 3.094 ± 0.026	4.827SerGly: 4.827 ± 0.041	1.958SerHis: 1.958 ± 0.022	3.607SerIle: 3.607 ± 0.031	4.531SerLys: 4.531 ± 0.032	8.216SerLeu: 8.216 ± 0.05	1.615SerMet: 1.615 ± 0.019	3.082SerAsn: 3.082 ± 0.025	5.272SerPro: 5.272 ± 0.05	3.588SerGln: 3.588 ± 0.034	4.089SerArg: 4.089 ± 0.032	8.966SerSer: 8.966 ± 0.088	4.383SerThr: 4.383 ± 0.031	5.083SerVal: 5.083 ± 0.032	0.983SerTrp: 0.983 ± 0.014	2.231SerTyr: 2.231 ± 0.02	0.001SerXaa: 0.001 ± 0.0
Thr	3.711ThrAla: 3.711 ± 0.031	1.323ThrCys: 1.323 ± 0.028	2.675ThrAsp: 2.675 ± 0.024	4.04ThrGlu: 4.04 ± 0.03	2.149ThrPhe: 2.149 ± 0.022	3.337ThrGly: 3.337 ± 0.027	1.183ThrHis: 1.183 ± 0.018	2.548ThrIle: 2.548 ± 0.024	2.939ThrLys: 2.939 ± 0.026	5.05ThrLeu: 5.05 ± 0.033	1.104ThrMet: 1.104 ± 0.015	1.965ThrAsn: 1.965 ± 0.02	2.998ThrPro: 2.998 ± 0.036	2.072ThrGln: 2.072 ± 0.02	2.504ThrArg: 2.504 ± 0.021	4.57ThrSer: 4.57 ± 0.043	2.921ThrThr: 2.921 ± 0.036	4.333ThrVal: 4.333 ± 0.035	0.653ThrTrp: 0.653 ± 0.011	1.545ThrTyr: 1.545 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.0ValAla: 4.0 ± 0.029	1.489ValCys: 1.489 ± 0.021	3.022ValAsp: 3.022 ± 0.024	4.288ValGlu: 4.288 ± 0.03	2.606ValPhe: 2.606 ± 0.023	3.181ValGly: 3.181 ± 0.028	1.557ValHis: 1.557 ± 0.016	3.67ValIle: 3.67 ± 0.027	3.814ValLys: 3.814 ± 0.031	6.273ValLeu: 6.273 ± 0.04	1.396ValMet: 1.396 ± 0.015	2.601ValAsn: 2.601 ± 0.025	3.334ValPro: 3.334 ± 0.029	2.822ValGln: 2.822 ± 0.027	3.224ValArg: 3.224 ± 0.025	4.88ValSer: 4.88 ± 0.033	4.129ValThr: 4.129 ± 0.032	4.387ValVal: 4.387 ± 0.034	0.703ValTrp: 0.703 ± 0.013	1.861ValTyr: 1.861 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.691TrpAla: 0.691 ± 0.013	0.237TrpCys: 0.237 ± 0.006	0.653TrpAsp: 0.653 ± 0.013	0.755TrpGlu: 0.755 ± 0.014	0.454TrpPhe: 0.454 ± 0.009	0.603TrpGly: 0.603 ± 0.015	0.335TrpHis: 0.335 ± 0.009	0.626TrpIle: 0.626 ± 0.013	0.927TrpLys: 0.927 ± 0.014	1.144TrpLeu: 1.144 ± 0.016	0.309TrpMet: 0.309 ± 0.007	0.859TrpAsn: 0.859 ± 0.013	0.429TrpPro: 0.429 ± 0.01	0.531TrpGln: 0.531 ± 0.009	0.662TrpArg: 0.662 ± 0.011	0.861TrpSer: 0.861 ± 0.014	0.668TrpThr: 0.668 ± 0.013	0.631TrpVal: 0.631 ± 0.011	0.191TrpTrp: 0.191 ± 0.006	0.367TrpTyr: 0.367 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.577TyrAla: 1.577 ± 0.018	0.793TyrCys: 0.793 ± 0.013	1.453TyrAsp: 1.453 ± 0.017	1.832TyrGlu: 1.832 ± 0.021	1.406TyrPhe: 1.406 ± 0.019	1.757TyrGly: 1.757 ± 0.019	0.794TyrHis: 0.794 ± 0.011	1.632TyrIle: 1.632 ± 0.015	1.772TyrLys: 1.772 ± 0.018	2.952TyrLeu: 2.952 ± 0.026	0.658TyrMet: 0.658 ± 0.01	1.312TyrAsn: 1.312 ± 0.017	1.347TyrPro: 1.347 ± 0.016	1.3TyrGln: 1.3 ± 0.016	1.7TyrArg: 1.7 ± 0.018	2.403TyrSer: 2.403 ± 0.024	1.614TyrThr: 1.614 ± 0.021	1.75TyrVal: 1.75 ± 0.018	0.396TyrTrp: 0.396 ± 0.013	1.095TyrTyr: 1.095 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.027XaaXaa: 0.027 ± 0.005

Statistics based on 13815 proteins (5684286 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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