Amino acid dipepetide frequency for Bacteriovorax stolpii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.118AlaAla: 5.118 ± 0.106	0.75AlaCys: 0.75 ± 0.025	3.431AlaAsp: 3.431 ± 0.056	4.535AlaGlu: 4.535 ± 0.073	3.545AlaPhe: 3.545 ± 0.054	4.667AlaGly: 4.667 ± 0.073	1.551AlaHis: 1.551 ± 0.04	4.755AlaIle: 4.755 ± 0.07	5.275AlaLys: 5.275 ± 0.067	7.603AlaLeu: 7.603 ± 0.087	1.992AlaMet: 1.992 ± 0.047	2.993AlaAsn: 2.993 ± 0.057	2.639AlaPro: 2.639 ± 0.06	2.683AlaGln: 2.683 ± 0.05	2.912AlaArg: 2.912 ± 0.047	4.768AlaSer: 4.768 ± 0.072	3.631AlaThr: 3.631 ± 0.063	4.281AlaVal: 4.281 ± 0.071	0.603AlaTrp: 0.603 ± 0.021	2.225AlaTyr: 2.225 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.688CysAla: 0.688 ± 0.024	0.104CysCys: 0.104 ± 0.01	0.56CysAsp: 0.56 ± 0.021	0.59CysGlu: 0.59 ± 0.024	0.548CysPhe: 0.548 ± 0.022	0.759CysGly: 0.759 ± 0.027	0.269CysHis: 0.269 ± 0.02	0.559CysIle: 0.559 ± 0.028	0.574CysLys: 0.574 ± 0.026	0.984CysLeu: 0.984 ± 0.028	0.252CysMet: 0.252 ± 0.016	0.393CysAsn: 0.393 ± 0.019	0.482CysPro: 0.482 ± 0.021	0.338CysGln: 0.338 ± 0.017	0.418CysArg: 0.418 ± 0.021	0.799CysSer: 0.799 ± 0.031	0.536CysThr: 0.536 ± 0.024	0.547CysVal: 0.547 ± 0.024	0.098CysTrp: 0.098 ± 0.013	0.335CysTyr: 0.335 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.249AspAla: 3.249 ± 0.053	0.51AspCys: 0.51 ± 0.021	2.504AspAsp: 2.504 ± 0.055	3.762AspGlu: 3.762 ± 0.062	3.259AspPhe: 3.259 ± 0.058	3.112AspGly: 3.112 ± 0.056	1.206AspHis: 1.206 ± 0.038	3.778AspIle: 3.778 ± 0.051	3.853AspLys: 3.853 ± 0.069	5.931AspLeu: 5.931 ± 0.075	1.282AspMet: 1.282 ± 0.036	2.204AspAsn: 2.204 ± 0.045	2.098AspPro: 2.098 ± 0.048	2.046AspGln: 2.046 ± 0.042	2.066AspArg: 2.066 ± 0.047	3.332AspSer: 3.332 ± 0.047	2.183AspThr: 2.183 ± 0.041	3.414AspVal: 3.414 ± 0.054	0.566AspTrp: 0.566 ± 0.022	2.357AspTyr: 2.357 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	5.046GluAla: 5.046 ± 0.071	0.577GluCys: 0.577 ± 0.021	3.317GluAsp: 3.317 ± 0.056	5.243GluGlu: 5.243 ± 0.088	3.183GluPhe: 3.183 ± 0.054	3.781GluGly: 3.781 ± 0.062	1.217GluHis: 1.217 ± 0.034	5.103GluIle: 5.103 ± 0.08	6.639GluLys: 6.639 ± 0.082	6.716GluLeu: 6.716 ± 0.087	2.045GluMet: 2.045 ± 0.046	3.463GluAsn: 3.463 ± 0.056	1.379GluPro: 1.379 ± 0.036	2.031GluGln: 2.031 ± 0.042	3.156GluArg: 3.156 ± 0.059	4.073GluSer: 4.073 ± 0.064	3.453GluThr: 3.453 ± 0.056	4.596GluVal: 4.596 ± 0.064	0.681GluTrp: 0.681 ± 0.024	2.184GluTyr: 2.184 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	3.351PheAla: 3.351 ± 0.054	0.585PheCys: 0.585 ± 0.023	2.934PheAsp: 2.934 ± 0.049	3.204PheGlu: 3.204 ± 0.053	3.14PhePhe: 3.14 ± 0.07	3.12PheGly: 3.12 ± 0.05	1.109PheHis: 1.109 ± 0.033	3.52PheIle: 3.52 ± 0.066	3.991PheLys: 3.991 ± 0.058	5.156PheLeu: 5.156 ± 0.089	1.368PheMet: 1.368 ± 0.035	2.736PheAsn: 2.736 ± 0.046	1.828PhePro: 1.828 ± 0.04	1.596PheGln: 1.596 ± 0.041	1.711PheArg: 1.711 ± 0.037	4.167PheSer: 4.167 ± 0.059	2.716PheThr: 2.716 ± 0.044	3.039PheVal: 3.039 ± 0.05	0.566PheTrp: 0.566 ± 0.022	2.17PheTyr: 2.17 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.499GlyAla: 4.499 ± 0.072	0.662GlyCys: 0.662 ± 0.026	3.167GlyAsp: 3.167 ± 0.054	4.026GlyGlu: 4.026 ± 0.071	3.14GlyPhe: 3.14 ± 0.055	4.304GlyGly: 4.304 ± 0.09	1.502GlyHis: 1.502 ± 0.033	4.475GlyIle: 4.475 ± 0.064	4.972GlyLys: 4.972 ± 0.072	6.216GlyLeu: 6.216 ± 0.082	1.709GlyMet: 1.709 ± 0.04	2.671GlyAsn: 2.671 ± 0.052	1.815GlyPro: 1.815 ± 0.045	2.064GlyGln: 2.064 ± 0.044	2.486GlyArg: 2.486 ± 0.049	4.098GlySer: 4.098 ± 0.072	3.574GlyThr: 3.574 ± 0.076	4.618GlyVal: 4.618 ± 0.07	0.632GlyTrp: 0.632 ± 0.022	2.219GlyTyr: 2.219 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	1.346HisAla: 1.346 ± 0.035	0.237HisCys: 0.237 ± 0.015	1.012HisAsp: 1.012 ± 0.032	1.287HisGlu: 1.287 ± 0.036	1.316HisPhe: 1.316 ± 0.034	1.232HisGly: 1.232 ± 0.033	0.651HisHis: 0.651 ± 0.025	1.234HisIle: 1.234 ± 0.032	1.184HisLys: 1.184 ± 0.035	2.076HisLeu: 2.076 ± 0.04	0.476HisMet: 0.476 ± 0.02	0.843HisAsn: 0.843 ± 0.025	1.117HisPro: 1.117 ± 0.031	0.729HisGln: 0.729 ± 0.027	0.764HisArg: 0.764 ± 0.025	1.355HisSer: 1.355 ± 0.031	0.954HisThr: 0.954 ± 0.031	1.126HisVal: 1.126 ± 0.032	0.205HisTrp: 0.205 ± 0.014	0.855HisTyr: 0.855 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.068IleAla: 5.068 ± 0.072	0.641IleCys: 0.641 ± 0.023	3.92IleAsp: 3.92 ± 0.057	4.855IleGlu: 4.855 ± 0.071	3.401IlePhe: 3.401 ± 0.058	4.31IleGly: 4.31 ± 0.068	1.362IleHis: 1.362 ± 0.042	4.393IleIle: 4.393 ± 0.058	5.358IleLys: 5.358 ± 0.072	6.545IleLeu: 6.545 ± 0.082	1.39IleMet: 1.39 ± 0.036	3.765IleAsn: 3.765 ± 0.052	2.905IlePro: 2.905 ± 0.047	2.338IleGln: 2.338 ± 0.048	2.516IleArg: 2.516 ± 0.046	4.996IleSer: 4.996 ± 0.06	3.725IleThr: 3.725 ± 0.061	4.358IleVal: 4.358 ± 0.061	0.566IleTrp: 0.566 ± 0.024	2.237IleTyr: 2.237 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	5.609LysAla: 5.609 ± 0.079	0.552LysCys: 0.552 ± 0.025	4.691LysAsp: 4.691 ± 0.065	6.385LysGlu: 6.385 ± 0.105	3.327LysPhe: 3.327 ± 0.058	4.43LysGly: 4.43 ± 0.065	1.291LysHis: 1.291 ± 0.032	6.187LysIle: 6.187 ± 0.078	8.465LysLys: 8.465 ± 0.111	7.004LysLeu: 7.004 ± 0.086	2.44LysMet: 2.44 ± 0.049	5.223LysAsn: 5.223 ± 0.075	2.228LysPro: 2.228 ± 0.05	1.968LysGln: 1.968 ± 0.039	3.197LysArg: 3.197 ± 0.049	5.122LysSer: 5.122 ± 0.061	4.965LysThr: 4.965 ± 0.064	5.11LysVal: 5.11 ± 0.068	0.71LysTrp: 0.71 ± 0.027	2.561LysTyr: 2.561 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	7.024LeuAla: 7.024 ± 0.086	0.984LeuCys: 0.984 ± 0.026	5.114LeuAsp: 5.114 ± 0.055	6.488LeuGlu: 6.488 ± 0.091	4.959LeuPhe: 4.959 ± 0.074	6.259LeuGly: 6.259 ± 0.082	1.711LeuHis: 1.711 ± 0.043	6.576LeuIle: 6.576 ± 0.084	8.972LeuLys: 8.972 ± 0.091	9.283LeuLeu: 9.283 ± 0.123	2.613LeuMet: 2.613 ± 0.056	5.097LeuAsn: 5.097 ± 0.07	3.845LeuPro: 3.845 ± 0.06	2.81LeuGln: 2.81 ± 0.046	3.833LeuArg: 3.833 ± 0.06	8.05LeuSer: 8.05 ± 0.094	5.407LeuThr: 5.407 ± 0.073	5.944LeuVal: 5.944 ± 0.068	0.828LeuTrp: 0.828 ± 0.028	3.008LeuTyr: 3.008 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.142MetAla: 2.142 ± 0.043	0.203MetCys: 0.203 ± 0.013	1.35MetAsp: 1.35 ± 0.033	1.537MetGlu: 1.537 ± 0.039	0.935MetPhe: 0.935 ± 0.029	1.847MetGly: 1.847 ± 0.042	0.363MetHis: 0.363 ± 0.019	1.947MetIle: 1.947 ± 0.041	2.918MetLys: 2.918 ± 0.054	2.126MetLeu: 2.126 ± 0.05	0.764MetMet: 0.764 ± 0.029	1.528MetAsn: 1.528 ± 0.032	0.924MetPro: 0.924 ± 0.028	0.754MetGln: 0.754 ± 0.03	1.083MetArg: 1.083 ± 0.03	1.958MetSer: 1.958 ± 0.039	1.615MetThr: 1.615 ± 0.036	1.608MetVal: 1.608 ± 0.04	0.176MetTrp: 0.176 ± 0.014	0.6MetTyr: 0.6 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.224AsnAla: 3.224 ± 0.061	0.504AsnCys: 0.504 ± 0.025	2.594AsnAsp: 2.594 ± 0.046	3.207AsnGlu: 3.207 ± 0.057	2.701AsnPhe: 2.701 ± 0.056	3.149AsnGly: 3.149 ± 0.061	1.056AsnHis: 1.056 ± 0.031	3.346AsnIle: 3.346 ± 0.051	3.506AsnLys: 3.506 ± 0.054	5.099AsnLeu: 5.099 ± 0.073	1.158AsnMet: 1.158 ± 0.03	2.415AsnAsn: 2.415 ± 0.053	2.474AsnPro: 2.474 ± 0.051	1.864AsnGln: 1.864 ± 0.041	1.963AsnArg: 1.963 ± 0.045	3.25AsnSer: 3.25 ± 0.056	2.507AsnThr: 2.507 ± 0.053	2.963AsnVal: 2.963 ± 0.05	0.507AsnTrp: 0.507 ± 0.022	1.99AsnTyr: 1.99 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	2.6ProAla: 2.6 ± 0.058	0.276ProCys: 0.276 ± 0.016	1.927ProAsp: 1.927 ± 0.046	3.018ProGlu: 3.018 ± 0.048	1.918ProPhe: 1.918 ± 0.04	2.37ProGly: 2.37 ± 0.049	0.814ProHis: 0.814 ± 0.029	2.202ProIle: 2.202 ± 0.048	2.821ProLys: 2.821 ± 0.054	3.366ProLeu: 3.366 ± 0.061	0.963ProMet: 0.963 ± 0.03	1.695ProAsn: 1.695 ± 0.042	1.027ProPro: 1.027 ± 0.037	1.231ProGln: 1.231 ± 0.032	1.262ProArg: 1.262 ± 0.033	2.354ProSer: 2.354 ± 0.054	1.933ProThr: 1.933 ± 0.046	2.716ProVal: 2.716 ± 0.047	0.402ProTrp: 0.402 ± 0.018	1.349ProTyr: 1.349 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	2.419GlnAla: 2.419 ± 0.053	0.287GlnCys: 0.287 ± 0.019	1.702GlnAsp: 1.702 ± 0.042	2.226GlnGlu: 2.226 ± 0.046	1.533GlnPhe: 1.533 ± 0.035	2.014GlnGly: 2.014 ± 0.046	0.471GlnHis: 0.471 ± 0.022	2.42GlnIle: 2.42 ± 0.045	3.134GlnLys: 3.134 ± 0.049	2.706GlnLeu: 2.706 ± 0.044	1.019GlnMet: 1.019 ± 0.031	1.724GlnAsn: 1.724 ± 0.043	0.785GlnPro: 0.785 ± 0.025	0.932GlnGln: 0.932 ± 0.036	1.286GlnArg: 1.286 ± 0.037	2.168GlnSer: 2.168 ± 0.044	1.855GlnThr: 1.855 ± 0.04	2.235GlnVal: 2.235 ± 0.045	0.3GlnTrp: 0.3 ± 0.016	1.113GlnTyr: 1.113 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.801ArgAla: 2.801 ± 0.05	0.341ArgCys: 0.341 ± 0.021	2.226ArgAsp: 2.226 ± 0.041	3.044ArgGlu: 3.044 ± 0.054	2.164ArgPhe: 2.164 ± 0.046	2.267ArgGly: 2.267 ± 0.045	0.738ArgHis: 0.738 ± 0.025	2.774ArgIle: 2.774 ± 0.048	2.756ArgLys: 2.756 ± 0.056	3.925ArgLeu: 3.925 ± 0.057	1.167ArgMet: 1.167 ± 0.034	1.841ArgAsn: 1.841 ± 0.04	1.535ArgPro: 1.535 ± 0.038	1.195ArgGln: 1.195 ± 0.036	1.486ArgArg: 1.486 ± 0.038	2.466ArgSer: 2.466 ± 0.044	1.916ArgThr: 1.916 ± 0.038	2.555ArgVal: 2.555 ± 0.043	0.376ArgTrp: 0.376 ± 0.018	1.411ArgTyr: 1.411 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.829SerAla: 4.829 ± 0.076	0.853SerCys: 0.853 ± 0.029	3.535SerAsp: 3.535 ± 0.051	4.36SerGlu: 4.36 ± 0.061	4.23SerPhe: 4.23 ± 0.066	4.675SerGly: 4.675 ± 0.081	1.39SerHis: 1.39 ± 0.037	4.429SerIle: 4.429 ± 0.064	4.799SerLys: 4.799 ± 0.067	7.616SerLeu: 7.616 ± 0.093	1.802SerMet: 1.802 ± 0.034	3.098SerAsn: 3.098 ± 0.06	2.586SerPro: 2.586 ± 0.046	2.337SerGln: 2.337 ± 0.041	2.542SerArg: 2.542 ± 0.044	5.21SerSer: 5.21 ± 0.102	3.781SerThr: 3.781 ± 0.067	4.4SerVal: 4.4 ± 0.066	0.74SerTrp: 0.74 ± 0.027	2.564SerTyr: 2.564 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	3.565ThrAla: 3.565 ± 0.069	0.551ThrCys: 0.551 ± 0.025	2.689ThrAsp: 2.689 ± 0.054	3.092ThrGlu: 3.092 ± 0.052	2.821ThrPhe: 2.821 ± 0.063	3.624ThrGly: 3.624 ± 0.076	1.136ThrHis: 1.136 ± 0.03	3.663ThrIle: 3.663 ± 0.062	4.09ThrLys: 4.09 ± 0.067	5.7ThrLeu: 5.7 ± 0.072	1.263ThrMet: 1.263 ± 0.037	2.598ThrAsn: 2.598 ± 0.054	2.638ThrPro: 2.638 ± 0.048	1.747ThrGln: 1.747 ± 0.037	1.919ThrArg: 1.919 ± 0.04	3.761ThrSer: 3.761 ± 0.067	3.351ThrThr: 3.351 ± 0.066	3.33ThrVal: 3.33 ± 0.062	0.489ThrTrp: 0.489 ± 0.022	2.052ThrTyr: 2.052 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	4.566ValAla: 4.566 ± 0.073	0.681ValCys: 0.681 ± 0.024	3.587ValAsp: 3.587 ± 0.056	4.328ValGlu: 4.328 ± 0.063	3.199ValPhe: 3.199 ± 0.055	4.063ValGly: 4.063 ± 0.069	1.217ValHis: 1.217 ± 0.036	4.47ValIle: 4.47 ± 0.065	4.806ValLys: 4.806 ± 0.08	6.305ValLeu: 6.305 ± 0.083	1.608ValMet: 1.608 ± 0.028	2.977ValAsn: 2.977 ± 0.052	2.226ValPro: 2.226 ± 0.048	1.92ValGln: 1.92 ± 0.039	2.439ValArg: 2.439 ± 0.05	4.648ValSer: 4.648 ± 0.071	3.702ValThr: 3.702 ± 0.055	4.634ValVal: 4.634 ± 0.072	0.56ValTrp: 0.56 ± 0.024	2.07ValTyr: 2.07 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.632TrpAla: 0.632 ± 0.024	0.105TrpCys: 0.105 ± 0.01	0.53TrpAsp: 0.53 ± 0.025	0.541TrpGlu: 0.541 ± 0.022	0.486TrpPhe: 0.486 ± 0.019	0.732TrpGly: 0.732 ± 0.027	0.184TrpHis: 0.184 ± 0.012	0.694TrpIle: 0.694 ± 0.025	0.718TrpLys: 0.718 ± 0.027	0.861TrpLeu: 0.861 ± 0.029	0.33TrpMet: 0.33 ± 0.017	0.51TrpAsn: 0.51 ± 0.02	0.328TrpPro: 0.328 ± 0.017	0.31TrpGln: 0.31 ± 0.016	0.353TrpArg: 0.353 ± 0.018	0.69TrpSer: 0.69 ± 0.028	0.476TrpThr: 0.476 ± 0.021	0.61TrpVal: 0.61 ± 0.022	0.142TrpTrp: 0.142 ± 0.012	0.287TrpTyr: 0.287 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.181TyrAla: 2.181 ± 0.044	0.426TyrCys: 0.426 ± 0.019	1.92TyrAsp: 1.92 ± 0.045	2.154TyrGlu: 2.154 ± 0.045	2.205TyrPhe: 2.205 ± 0.047	2.136TyrGly: 2.136 ± 0.045	0.761TyrHis: 0.761 ± 0.027	2.126TyrIle: 2.126 ± 0.041	2.635TyrLys: 2.635 ± 0.054	3.587TyrLeu: 3.587 ± 0.059	0.734TyrMet: 0.734 ± 0.026	1.707TyrAsn: 1.707 ± 0.042	1.386TyrPro: 1.386 ± 0.045	1.435TyrGln: 1.435 ± 0.035	1.59TyrArg: 1.59 ± 0.044	2.511TyrSer: 2.511 ± 0.048	1.799TyrThr: 1.799 ± 0.039	1.921TyrVal: 1.921 ± 0.039	0.371TyrTrp: 0.371 ± 0.018	1.468TyrTyr: 1.468 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3721 proteins (1179481 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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