Amino acid dipepetide frequency for Avian paramyxovirus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.994AlaAla: 5.994 ± 0.587
0.999AlaCys: 0.999 ± 0.533
2.198AlaAsp: 2.198 ± 0.354
3.996AlaGlu: 3.996 ± 0.649
2.797AlaPhe: 2.797 ± 0.799
3.397AlaGly: 3.397 ± 0.688
1.199AlaHis: 1.199 ± 0.394
5.195AlaIle: 5.195 ± 0.932
1.798AlaLys: 1.798 ± 0.483
7.792AlaLeu: 7.792 ± 1.549
2.597AlaMet: 2.597 ± 1.842
2.198AlaAsn: 2.198 ± 0.875
2.198AlaPro: 2.198 ± 0.86
3.596AlaGln: 3.596 ± 1.232
3.197AlaArg: 3.197 ± 1.135
6.993AlaSer: 6.993 ± 1.036
3.397AlaThr: 3.397 ± 1.071
4.995AlaVal: 4.995 ± 1.388
0.999AlaTrp: 0.999 ± 0.464
1.998AlaTyr: 1.998 ± 0.557
0.0AlaXaa: 0.0 ± 0.0
Cys
0.799CysAla: 0.799 ± 0.391
0.2CysCys: 0.2 ± 0.126
1.399CysAsp: 1.399 ± 0.69
0.999CysGlu: 0.999 ± 0.491
0.4CysPhe: 0.4 ± 0.424
1.399CysGly: 1.399 ± 0.599
0.4CysHis: 0.4 ± 0.267
1.598CysIle: 1.598 ± 0.559
0.799CysLys: 0.799 ± 0.451
1.798CysLeu: 1.798 ± 0.606
0.599CysMet: 0.599 ± 0.377
1.798CysAsn: 1.798 ± 0.475
0.799CysPro: 0.799 ± 0.314
1.399CysGln: 1.399 ± 0.557
0.999CysArg: 0.999 ± 0.348
1.998CysSer: 1.998 ± 0.467
0.799CysThr: 0.799 ± 0.287
1.598CysVal: 1.598 ± 0.618
0.0CysTrp: 0.0 ± 0.0
0.799CysTyr: 0.799 ± 0.35
0.0CysXaa: 0.0 ± 0.0
Asp
2.797AspAla: 2.797 ± 0.801
0.599AspCys: 0.599 ± 0.264
3.796AspAsp: 3.796 ± 0.891
2.198AspGlu: 2.198 ± 0.605
1.798AspPhe: 1.798 ± 0.459
1.998AspGly: 1.998 ± 0.694
0.4AspHis: 0.4 ± 0.447
4.196AspIle: 4.196 ± 0.75
2.997AspLys: 2.997 ± 0.76
5.994AspLeu: 5.994 ± 1.662
1.998AspMet: 1.998 ± 0.646
3.796AspAsn: 3.796 ± 1.234
3.996AspPro: 3.996 ± 0.708
2.997AspGln: 2.997 ± 1.205
1.998AspArg: 1.998 ± 0.53
4.795AspSer: 4.795 ± 0.959
3.596AspThr: 3.596 ± 0.75
1.998AspVal: 1.998 ± 0.559
0.4AspTrp: 0.4 ± 0.369
2.198AspTyr: 2.198 ± 0.476
0.0AspXaa: 0.0 ± 0.0
Glu
2.398GluAla: 2.398 ± 0.362
0.999GluCys: 0.999 ± 0.356
3.796GluAsp: 3.796 ± 1.355
3.996GluGlu: 3.996 ± 0.752
2.198GluPhe: 2.198 ± 0.545
3.996GluGly: 3.996 ± 0.749
1.199GluHis: 1.199 ± 0.332
3.197GluIle: 3.197 ± 0.852
3.596GluLys: 3.596 ± 0.499
5.794GluLeu: 5.794 ± 1.014
1.199GluMet: 1.199 ± 0.533
2.997GluAsn: 2.997 ± 0.757
1.399GluPro: 1.399 ± 0.403
2.198GluGln: 2.198 ± 0.42
0.799GluArg: 0.799 ± 0.337
5.594GluSer: 5.594 ± 0.72
4.595GluThr: 4.595 ± 2.189
3.996GluVal: 3.996 ± 1.526
0.999GluTrp: 0.999 ± 0.357
2.398GluTyr: 2.398 ± 0.643
0.0GluXaa: 0.0 ± 0.0
Phe
2.198PheAla: 2.198 ± 0.689
1.199PheCys: 1.199 ± 0.417
1.399PheAsp: 1.399 ± 0.477
2.597PheGlu: 2.597 ± 0.996
2.398PhePhe: 2.398 ± 0.756
0.999PheGly: 0.999 ± 0.361
0.599PheHis: 0.599 ± 0.264
1.399PheIle: 1.399 ± 0.448
2.398PheLys: 2.398 ± 0.84
4.396PheLeu: 4.396 ± 0.906
0.4PheMet: 0.4 ± 0.486
0.999PheAsn: 0.999 ± 0.497
0.999PhePro: 0.999 ± 0.535
0.999PheGln: 0.999 ± 0.65
2.398PheArg: 2.398 ± 0.756
3.197PheSer: 3.197 ± 0.969
1.798PheThr: 1.798 ± 0.655
1.399PheVal: 1.399 ± 0.573
0.0PheTrp: 0.0 ± 0.0
0.799PheTyr: 0.799 ± 0.352
0.0PheXaa: 0.0 ± 0.0
Gly
3.397GlyAla: 3.397 ± 0.905
1.399GlyCys: 1.399 ± 0.451
6.194GlyAsp: 6.194 ± 1.318
3.596GlyGlu: 3.596 ± 0.684
1.998GlyPhe: 1.998 ± 0.954
4.795GlyGly: 4.795 ± 0.871
0.799GlyHis: 0.799 ± 0.372
4.396GlyIle: 4.396 ± 1.028
4.396GlyLys: 4.396 ± 1.294
5.994GlyLeu: 5.994 ± 1.152
0.999GlyMet: 0.999 ± 0.395
2.797GlyAsn: 2.797 ± 0.991
2.398GlyPro: 2.398 ± 1.36
1.399GlyGln: 1.399 ± 0.653
3.397GlyArg: 3.397 ± 0.766
5.395GlySer: 5.395 ± 1.16
3.397GlyThr: 3.397 ± 0.705
4.795GlyVal: 4.795 ± 1.008
0.799GlyTrp: 0.799 ± 0.508
0.799GlyTyr: 0.799 ± 0.448
0.0GlyXaa: 0.0 ± 0.0
His
1.998HisAla: 1.998 ± 0.653
0.2HisCys: 0.2 ± 0.126
0.2HisAsp: 0.2 ± 0.126
0.599HisGlu: 0.599 ± 0.287
0.2HisPhe: 0.2 ± 0.126
1.598HisGly: 1.598 ± 0.66
0.4HisHis: 0.4 ± 0.251
0.4HisIle: 0.4 ± 0.251
0.0HisLys: 0.0 ± 0.0
1.998HisLeu: 1.998 ± 1.055
0.0HisMet: 0.0 ± 0.0
0.999HisAsn: 0.999 ± 0.468
1.399HisPro: 1.399 ± 0.596
1.199HisGln: 1.199 ± 0.357
0.599HisArg: 0.599 ± 0.291
1.998HisSer: 1.998 ± 0.718
0.599HisThr: 0.599 ± 0.377
0.999HisVal: 0.999 ± 0.65
0.2HisTrp: 0.2 ± 0.238
0.2HisTyr: 0.2 ± 0.324
0.0HisXaa: 0.0 ± 0.0
Ile
4.795IleAla: 4.795 ± 1.368
0.999IleCys: 0.999 ± 0.458
2.597IleAsp: 2.597 ± 0.793
4.396IleGlu: 4.396 ± 1.186
2.198IlePhe: 2.198 ± 1.139
5.395IleGly: 5.395 ± 0.979
1.399IleHis: 1.399 ± 0.501
5.395IleIle: 5.395 ± 1.499
5.195IleLys: 5.195 ± 1.275
3.596IleLeu: 3.596 ± 0.907
1.598IleMet: 1.598 ± 0.942
4.196IleAsn: 4.196 ± 0.899
3.996IlePro: 3.996 ± 0.873
3.996IleGln: 3.996 ± 0.429
3.796IleArg: 3.796 ± 1.083
6.993IleSer: 6.993 ± 0.969
4.396IleThr: 4.396 ± 1.589
5.195IleVal: 5.195 ± 1.19
0.2IleTrp: 0.2 ± 0.27
1.998IleTyr: 1.998 ± 0.885
0.0IleXaa: 0.0 ± 0.0
Lys
4.795LysAla: 4.795 ± 1.913
1.399LysCys: 1.399 ± 0.44
1.798LysAsp: 1.798 ± 0.695
4.396LysGlu: 4.396 ± 0.481
1.399LysPhe: 1.399 ± 0.69
3.596LysGly: 3.596 ± 0.757
0.799LysHis: 0.799 ± 0.33
4.595LysIle: 4.595 ± 0.794
2.198LysLys: 2.198 ± 0.388
3.796LysLeu: 3.796 ± 0.761
1.798LysMet: 1.798 ± 0.842
3.996LysAsn: 3.996 ± 0.831
2.198LysPro: 2.198 ± 1.374
0.799LysGln: 0.799 ± 0.362
3.197LysArg: 3.197 ± 1.61
5.594LysSer: 5.594 ± 1.042
3.996LysThr: 3.996 ± 1.59
4.995LysVal: 4.995 ± 0.988
0.599LysTrp: 0.599 ± 0.264
1.798LysTyr: 1.798 ± 0.566
0.0LysXaa: 0.0 ± 0.0
Leu
6.194LeuAla: 6.194 ± 1.622
1.998LeuCys: 1.998 ± 0.618
6.394LeuAsp: 6.394 ± 1.306
5.195LeuGlu: 5.195 ± 1.417
3.996LeuPhe: 3.996 ± 2.085
4.396LeuGly: 4.396 ± 0.774
1.399LeuHis: 1.399 ± 0.353
4.795LeuIle: 4.795 ± 1.178
5.994LeuLys: 5.994 ± 0.992
10.19LeuLeu: 10.19 ± 1.168
1.399LeuMet: 1.399 ± 0.505
4.196LeuAsn: 4.196 ± 0.533
2.198LeuPro: 2.198 ± 0.781
2.597LeuGln: 2.597 ± 0.364
5.395LeuArg: 5.395 ± 1.142
8.991LeuSer: 8.991 ± 2.235
7.193LeuThr: 7.193 ± 1.316
5.794LeuVal: 5.794 ± 0.897
2.198LeuTrp: 2.198 ± 0.766
3.596LeuTyr: 3.596 ± 1.243
0.0LeuXaa: 0.0 ± 0.0
Met
1.998MetAla: 1.998 ± 0.845
0.599MetCys: 0.599 ± 0.377
1.399MetAsp: 1.399 ± 0.684
0.799MetGlu: 0.799 ± 0.528
0.999MetPhe: 0.999 ± 0.533
1.798MetGly: 1.798 ± 0.472
0.2MetHis: 0.2 ± 0.126
2.198MetIle: 2.198 ± 0.709
0.4MetLys: 0.4 ± 0.486
1.798MetLeu: 1.798 ± 0.445
0.599MetMet: 0.599 ± 0.492
1.399MetAsn: 1.399 ± 0.403
0.599MetPro: 0.599 ± 0.32
0.2MetGln: 0.2 ± 0.223
0.599MetArg: 0.599 ± 0.469
2.398MetSer: 2.398 ± 1.071
2.597MetThr: 2.597 ± 0.595
1.199MetVal: 1.199 ± 0.454
0.4MetTrp: 0.4 ± 0.251
0.599MetTyr: 0.599 ± 0.264
0.0MetXaa: 0.0 ± 0.0
Asn
3.397AsnAla: 3.397 ± 0.867
1.199AsnCys: 1.199 ± 0.375
2.797AsnAsp: 2.797 ± 0.894
3.197AsnGlu: 3.197 ± 0.863
0.999AsnPhe: 0.999 ± 0.52
2.797AsnGly: 2.797 ± 0.458
0.2AsnHis: 0.2 ± 0.126
5.195AsnIle: 5.195 ± 1.235
2.398AsnLys: 2.398 ± 0.463
4.795AsnLeu: 4.795 ± 0.97
0.999AsnMet: 0.999 ± 0.417
1.399AsnAsn: 1.399 ± 0.518
3.197AsnPro: 3.197 ± 0.702
1.798AsnGln: 1.798 ± 0.579
2.997AsnArg: 2.997 ± 0.988
3.197AsnSer: 3.197 ± 1.052
4.595AsnThr: 4.595 ± 2.305
1.199AsnVal: 1.199 ± 0.422
0.799AsnTrp: 0.799 ± 0.503
1.998AsnTyr: 1.998 ± 0.852
0.0AsnXaa: 0.0 ± 0.0
Pro
2.997ProAla: 2.997 ± 0.821
0.999ProCys: 0.999 ± 0.397
2.997ProAsp: 2.997 ± 1.361
2.797ProGlu: 2.797 ± 1.114
0.799ProPhe: 0.799 ± 0.33
2.797ProGly: 2.797 ± 1.323
0.4ProHis: 0.4 ± 0.267
2.997ProIle: 2.997 ± 0.603
2.398ProLys: 2.398 ± 0.604
3.197ProLeu: 3.197 ± 1.24
0.4ProMet: 0.4 ± 0.242
1.998ProAsn: 1.998 ± 0.632
1.598ProPro: 1.598 ± 0.394
2.997ProGln: 2.997 ± 0.928
2.597ProArg: 2.597 ± 0.789
3.197ProSer: 3.197 ± 0.864
2.398ProThr: 2.398 ± 0.82
1.798ProVal: 1.798 ± 0.54
0.4ProTrp: 0.4 ± 0.218
1.199ProTyr: 1.199 ± 0.574
0.0ProXaa: 0.0 ± 0.0
Gln
2.398GlnAla: 2.398 ± 1.19
0.2GlnCys: 0.2 ± 0.126
2.198GlnAsp: 2.198 ± 0.396
1.798GlnGlu: 1.798 ± 0.779
0.999GlnPhe: 0.999 ± 0.395
2.597GlnGly: 2.597 ± 0.877
1.199GlnHis: 1.199 ± 0.636
3.996GlnIle: 3.996 ± 0.755
3.596GlnLys: 3.596 ± 0.874
5.195GlnLeu: 5.195 ± 1.382
0.599GlnMet: 0.599 ± 0.425
1.998GlnAsn: 1.998 ± 0.738
1.798GlnPro: 1.798 ± 0.602
1.399GlnGln: 1.399 ± 0.661
1.399GlnArg: 1.399 ± 0.409
3.397GlnSer: 3.397 ± 0.794
1.998GlnThr: 1.998 ± 0.501
2.198GlnVal: 2.198 ± 0.655
0.2GlnTrp: 0.2 ± 0.27
1.399GlnTyr: 1.399 ± 0.518
0.0GlnXaa: 0.0 ± 0.0
Arg
2.997ArgAla: 2.997 ± 0.962
0.4ArgCys: 0.4 ± 0.218
2.398ArgAsp: 2.398 ± 0.897
2.997ArgGlu: 2.997 ± 0.691
1.199ArgPhe: 1.199 ± 0.715
3.596ArgGly: 3.596 ± 1.092
0.799ArgHis: 0.799 ± 0.352
2.997ArgIle: 2.997 ± 0.702
2.198ArgLys: 2.198 ± 0.595
3.596ArgLeu: 3.596 ± 0.657
0.799ArgMet: 0.799 ± 0.483
3.197ArgAsn: 3.197 ± 0.698
1.998ArgPro: 1.998 ± 0.818
1.798ArgGln: 1.798 ± 0.586
3.397ArgArg: 3.397 ± 0.934
3.397ArgSer: 3.397 ± 0.846
3.796ArgThr: 3.796 ± 1.115
4.995ArgVal: 4.995 ± 1.027
0.4ArgTrp: 0.4 ± 0.372
1.598ArgTyr: 1.598 ± 0.659
0.0ArgXaa: 0.0 ± 0.0
Ser
5.594SerAla: 5.594 ± 1.708
1.399SerCys: 1.399 ± 0.452
6.593SerAsp: 6.593 ± 1.801
3.596SerGlu: 3.596 ± 0.714
3.397SerPhe: 3.397 ± 0.893
7.592SerGly: 7.592 ± 1.53
1.199SerHis: 1.199 ± 0.39
6.793SerIle: 6.793 ± 1.567
5.195SerLys: 5.195 ± 1.433
8.392SerLeu: 8.392 ± 1.488
2.797SerMet: 2.797 ± 0.802
4.995SerAsn: 4.995 ± 1.785
5.195SerPro: 5.195 ± 0.972
2.997SerGln: 2.997 ± 0.819
3.397SerArg: 3.397 ± 0.651
8.991SerSer: 8.991 ± 0.947
4.995SerThr: 4.995 ± 0.763
5.994SerVal: 5.994 ± 1.115
1.199SerTrp: 1.199 ± 0.572
1.598SerTyr: 1.598 ± 0.555
0.0SerXaa: 0.0 ± 0.0
Thr
5.395ThrAla: 5.395 ± 1.51
1.399ThrCys: 1.399 ± 0.528
2.398ThrAsp: 2.398 ± 0.823
3.796ThrGlu: 3.796 ± 1.541
1.399ThrPhe: 1.399 ± 0.501
4.396ThrGly: 4.396 ± 0.779
1.598ThrHis: 1.598 ± 0.576
5.594ThrIle: 5.594 ± 0.346
5.395ThrLys: 5.395 ± 1.977
5.794ThrLeu: 5.794 ± 1.213
1.598ThrMet: 1.598 ± 0.449
1.798ThrAsn: 1.798 ± 0.738
1.598ThrPro: 1.598 ± 0.662
4.196ThrGln: 4.196 ± 1.413
3.397ThrArg: 3.397 ± 0.571
6.793ThrSer: 6.793 ± 0.989
5.195ThrThr: 5.195 ± 1.582
3.596ThrVal: 3.596 ± 0.676
1.199ThrTrp: 1.199 ± 0.529
1.399ThrTyr: 1.399 ± 0.542
0.0ThrXaa: 0.0 ± 0.0
Val
4.196ValAla: 4.196 ± 1.607
2.198ValCys: 2.198 ± 0.568
2.597ValAsp: 2.597 ± 0.778
2.997ValGlu: 2.997 ± 0.898
1.399ValPhe: 1.399 ± 0.487
3.796ValGly: 3.796 ± 0.878
0.999ValHis: 0.999 ± 0.336
3.596ValIle: 3.596 ± 0.717
4.795ValLys: 4.795 ± 0.983
6.793ValLeu: 6.793 ± 0.843
1.399ValMet: 1.399 ± 0.48
3.197ValAsn: 3.197 ± 0.985
1.598ValPro: 1.598 ± 0.538
2.398ValGln: 2.398 ± 0.404
3.596ValArg: 3.596 ± 0.726
5.594ValSer: 5.594 ± 1.097
5.994ValThr: 5.994 ± 1.122
2.198ValVal: 2.198 ± 1.097
0.599ValTrp: 0.599 ± 0.387
1.598ValTyr: 1.598 ± 0.852
0.0ValXaa: 0.0 ± 0.0
Trp
0.599TrpAla: 0.599 ± 0.291
0.799TrpCys: 0.799 ± 0.381
0.2TrpAsp: 0.2 ± 0.126
1.598TrpGlu: 1.598 ± 0.604
0.4TrpPhe: 0.4 ± 0.251
0.999TrpGly: 0.999 ± 0.434
0.2TrpHis: 0.2 ± 0.126
0.799TrpIle: 0.799 ± 0.489
0.599TrpLys: 0.599 ± 0.264
0.4TrpLeu: 0.4 ± 0.251
0.4TrpMet: 0.4 ± 0.251
0.0TrpAsn: 0.0 ± 0.0
0.799TrpPro: 0.799 ± 0.549
0.2TrpGln: 0.2 ± 0.126
0.799TrpArg: 0.799 ± 0.436
1.199TrpSer: 1.199 ± 0.806
0.4TrpThr: 0.4 ± 0.218
0.799TrpVal: 0.799 ± 0.503
0.2TrpTrp: 0.2 ± 0.238
0.4TrpTyr: 0.4 ± 0.251
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.597TyrAla: 2.597 ± 1.074
1.399TyrCys: 1.399 ± 0.542
1.199TyrAsp: 1.199 ± 0.533
1.798TyrGlu: 1.798 ± 0.517
1.598TyrPhe: 1.598 ± 0.645
1.199TyrGly: 1.199 ± 0.754
0.4TyrHis: 0.4 ± 0.267
2.997TyrIle: 2.997 ± 1.373
1.399TyrLys: 1.399 ± 0.61
2.797TyrLeu: 2.797 ± 0.953
0.4TyrMet: 0.4 ± 0.251
1.199TyrAsn: 1.199 ± 0.638
0.999TyrPro: 0.999 ± 0.31
1.399TyrGln: 1.399 ± 0.672
0.799TyrArg: 0.799 ± 0.382
2.198TyrSer: 2.198 ± 0.355
2.198TyrThr: 2.198 ± 0.682
1.798TyrVal: 1.798 ± 0.626
0.0TyrTrp: 0.0 ± 0.0
0.799TyrTyr: 0.799 ± 0.438
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5006 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski