Amino acid dipepetide frequency for Avian metaavulavirus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.842AlaAla: 3.842 ± 0.871
0.404AlaCys: 0.404 ± 0.376
2.224AlaAsp: 2.224 ± 0.649
4.247AlaGlu: 4.247 ± 0.771
1.82AlaPhe: 1.82 ± 0.784
3.236AlaGly: 3.236 ± 0.886
0.404AlaHis: 0.404 ± 0.235
4.044AlaIle: 4.044 ± 0.529
2.831AlaLys: 2.831 ± 0.738
6.471AlaLeu: 6.471 ± 1.333
2.022AlaMet: 2.022 ± 0.673
3.033AlaAsn: 3.033 ± 1.021
2.831AlaPro: 2.831 ± 0.503
2.022AlaGln: 2.022 ± 0.916
3.64AlaArg: 3.64 ± 0.889
5.865AlaSer: 5.865 ± 1.217
3.438AlaThr: 3.438 ± 0.801
3.64AlaVal: 3.64 ± 1.191
0.404AlaTrp: 0.404 ± 0.355
1.618AlaTyr: 1.618 ± 0.581
0.0AlaXaa: 0.0 ± 0.0
Cys
1.416CysAla: 1.416 ± 0.71
0.202CysCys: 0.202 ± 0.124
1.213CysAsp: 1.213 ± 0.557
0.404CysGlu: 0.404 ± 0.397
0.809CysPhe: 0.809 ± 0.228
0.404CysGly: 0.404 ± 0.259
0.607CysHis: 0.607 ± 0.316
1.416CysIle: 1.416 ± 0.455
1.416CysLys: 1.416 ± 0.604
1.82CysLeu: 1.82 ± 0.39
0.607CysMet: 0.607 ± 0.278
1.213CysAsn: 1.213 ± 0.377
1.011CysPro: 1.011 ± 0.411
0.809CysGln: 0.809 ± 0.495
0.809CysArg: 0.809 ± 0.5
2.224CysSer: 2.224 ± 0.604
1.213CysThr: 1.213 ± 0.29
1.213CysVal: 1.213 ± 0.331
0.0CysTrp: 0.0 ± 0.0
0.607CysTyr: 0.607 ± 0.457
0.0CysXaa: 0.0 ± 0.0
Asp
2.022AspAla: 2.022 ± 0.446
0.607AspCys: 0.607 ± 0.266
2.831AspAsp: 2.831 ± 1.206
2.629AspGlu: 2.629 ± 1.038
2.224AspPhe: 2.224 ± 0.955
1.618AspGly: 1.618 ± 0.541
1.618AspHis: 1.618 ± 0.464
2.629AspIle: 2.629 ± 0.948
3.033AspLys: 3.033 ± 0.91
6.067AspLeu: 6.067 ± 1.146
1.011AspMet: 1.011 ± 0.968
3.438AspAsn: 3.438 ± 1.072
3.842AspPro: 3.842 ± 0.998
3.842AspGln: 3.842 ± 0.323
2.831AspArg: 2.831 ± 0.596
4.044AspSer: 4.044 ± 0.699
3.842AspThr: 3.842 ± 0.916
1.618AspVal: 1.618 ± 0.503
0.202AspTrp: 0.202 ± 0.124
1.618AspTyr: 1.618 ± 0.532
0.0AspXaa: 0.0 ± 0.0
Glu
1.82GluAla: 1.82 ± 0.718
0.809GluCys: 0.809 ± 0.731
1.618GluAsp: 1.618 ± 0.862
3.64GluGlu: 3.64 ± 0.65
2.427GluPhe: 2.427 ± 1.063
3.64GluGly: 3.64 ± 0.813
1.213GluHis: 1.213 ± 0.328
4.449GluIle: 4.449 ± 0.623
2.224GluLys: 2.224 ± 0.757
6.471GluLeu: 6.471 ± 0.888
1.416GluMet: 1.416 ± 0.475
2.629GluAsn: 2.629 ± 0.796
1.416GluPro: 1.416 ± 0.762
2.629GluGln: 2.629 ± 0.84
2.427GluArg: 2.427 ± 0.628
6.876GluSer: 6.876 ± 1.305
2.224GluThr: 2.224 ± 0.541
3.033GluVal: 3.033 ± 0.398
0.607GluTrp: 0.607 ± 0.259
1.618GluTyr: 1.618 ± 0.433
0.0GluXaa: 0.0 ± 0.0
Phe
1.82PheAla: 1.82 ± 0.42
0.607PheCys: 0.607 ± 0.371
1.011PheAsp: 1.011 ± 0.441
2.224PheGlu: 2.224 ± 1.145
3.236PhePhe: 3.236 ± 0.991
1.618PheGly: 1.618 ± 0.548
0.202PheHis: 0.202 ± 0.198
2.629PheIle: 2.629 ± 0.566
1.82PheLys: 1.82 ± 0.599
4.247PheLeu: 4.247 ± 0.912
0.607PheMet: 0.607 ± 0.471
1.618PheAsn: 1.618 ± 0.501
0.809PhePro: 0.809 ± 0.463
0.404PheGln: 0.404 ± 0.232
1.416PheArg: 1.416 ± 0.523
2.224PheSer: 2.224 ± 0.832
2.427PheThr: 2.427 ± 0.488
2.831PheVal: 2.831 ± 0.889
0.202PheTrp: 0.202 ± 0.124
0.607PheTyr: 0.607 ± 0.266
0.0PheXaa: 0.0 ± 0.0
Gly
2.831GlyAla: 2.831 ± 0.507
1.618GlyCys: 1.618 ± 0.598
4.853GlyAsp: 4.853 ± 0.899
1.618GlyGlu: 1.618 ± 0.486
1.82GlyPhe: 1.82 ± 0.494
2.427GlyGly: 2.427 ± 0.805
2.224GlyHis: 2.224 ± 1.004
4.651GlyIle: 4.651 ± 0.962
1.011GlyLys: 1.011 ± 0.336
5.258GlyLeu: 5.258 ± 1.104
0.607GlyMet: 0.607 ± 0.278
1.618GlyAsn: 1.618 ± 0.926
1.618GlyPro: 1.618 ± 0.524
1.82GlyGln: 1.82 ± 0.568
3.033GlyArg: 3.033 ± 0.548
5.056GlySer: 5.056 ± 1.021
3.438GlyThr: 3.438 ± 1.129
4.651GlyVal: 4.651 ± 1.379
0.0GlyTrp: 0.0 ± 0.0
2.022GlyTyr: 2.022 ± 0.534
0.0GlyXaa: 0.0 ± 0.0
His
1.011HisAla: 1.011 ± 0.327
0.0HisCys: 0.0 ± 0.0
1.618HisAsp: 1.618 ± 0.516
0.202HisGlu: 0.202 ± 0.273
0.809HisPhe: 0.809 ± 0.407
0.809HisGly: 0.809 ± 0.359
0.809HisHis: 0.809 ± 0.495
1.618HisIle: 1.618 ± 0.333
0.404HisLys: 0.404 ± 0.253
3.033HisLeu: 3.033 ± 1.115
0.202HisMet: 0.202 ± 0.117
0.607HisAsn: 0.607 ± 0.236
3.033HisPro: 3.033 ± 0.952
1.011HisGln: 1.011 ± 0.812
0.809HisArg: 0.809 ± 0.297
2.022HisSer: 2.022 ± 0.838
1.011HisThr: 1.011 ± 0.462
0.809HisVal: 0.809 ± 0.316
0.607HisTrp: 0.607 ± 0.431
0.404HisTyr: 0.404 ± 0.18
0.0HisXaa: 0.0 ± 0.0
Ile
3.842IleAla: 3.842 ± 0.547
0.202IleCys: 0.202 ± 0.124
4.651IleAsp: 4.651 ± 1.022
5.056IleGlu: 5.056 ± 0.69
2.022IlePhe: 2.022 ± 0.543
4.044IleGly: 4.044 ± 1.018
1.618IleHis: 1.618 ± 0.604
5.46IleIle: 5.46 ± 1.276
5.865IleLys: 5.865 ± 0.78
6.876IleLeu: 6.876 ± 0.994
2.427IleMet: 2.427 ± 0.598
4.853IleAsn: 4.853 ± 0.834
5.056IlePro: 5.056 ± 0.507
3.64IleGln: 3.64 ± 0.623
3.236IleArg: 3.236 ± 0.88
7.887IleSer: 7.887 ± 1.1
6.067IleThr: 6.067 ± 1.326
5.056IleVal: 5.056 ± 1.715
1.416IleTrp: 1.416 ± 0.494
2.224IleTyr: 2.224 ± 0.816
0.0IleXaa: 0.0 ± 0.0
Lys
1.82LysAla: 1.82 ± 0.436
1.011LysCys: 1.011 ± 0.376
2.629LysAsp: 2.629 ± 0.87
4.853LysGlu: 4.853 ± 0.833
1.416LysPhe: 1.416 ± 0.568
3.033LysGly: 3.033 ± 0.8
0.607LysHis: 0.607 ± 0.29
4.044LysIle: 4.044 ± 1.361
2.427LysLys: 2.427 ± 0.739
4.853LysLeu: 4.853 ± 1.029
1.416LysMet: 1.416 ± 0.51
3.842LysAsn: 3.842 ± 0.81
0.809LysPro: 0.809 ± 0.33
1.011LysGln: 1.011 ± 0.318
2.629LysArg: 2.629 ± 0.661
5.662LysSer: 5.662 ± 1.192
2.831LysThr: 2.831 ± 0.884
1.82LysVal: 1.82 ± 0.782
0.607LysTrp: 0.607 ± 0.236
1.416LysTyr: 1.416 ± 0.478
0.0LysXaa: 0.0 ± 0.0
Leu
8.493LeuAla: 8.493 ± 1.244
2.629LeuCys: 2.629 ± 0.665
7.482LeuAsp: 7.482 ± 0.984
4.651LeuGlu: 4.651 ± 1.108
2.831LeuPhe: 2.831 ± 1.159
5.056LeuGly: 5.056 ± 1.36
1.618LeuHis: 1.618 ± 0.802
9.707LeuIle: 9.707 ± 2.003
4.853LeuLys: 4.853 ± 0.721
12.336LeuLeu: 12.336 ± 1.906
1.213LeuMet: 1.213 ± 0.553
7.28LeuAsn: 7.28 ± 1.013
5.258LeuPro: 5.258 ± 0.525
3.033LeuGln: 3.033 ± 0.366
5.258LeuArg: 5.258 ± 1.887
9.505LeuSer: 9.505 ± 1.406
8.089LeuThr: 8.089 ± 0.71
4.247LeuVal: 4.247 ± 1.008
1.416LeuTrp: 1.416 ± 0.389
4.449LeuTyr: 4.449 ± 1.064
0.0LeuXaa: 0.0 ± 0.0
Met
1.82MetAla: 1.82 ± 0.933
0.809MetCys: 0.809 ± 0.36
0.809MetAsp: 0.809 ± 0.358
0.809MetGlu: 0.809 ± 0.366
0.607MetPhe: 0.607 ± 0.266
1.82MetGly: 1.82 ± 1.152
0.0MetHis: 0.0 ± 0.0
1.416MetIle: 1.416 ± 0.688
1.82MetLys: 1.82 ± 0.994
1.011MetLeu: 1.011 ± 0.278
0.202MetMet: 0.202 ± 0.198
0.607MetAsn: 0.607 ± 0.305
0.809MetPro: 0.809 ± 0.364
0.809MetGln: 0.809 ± 0.341
2.022MetArg: 2.022 ± 0.504
1.618MetSer: 1.618 ± 0.544
1.618MetThr: 1.618 ± 0.597
1.416MetVal: 1.416 ± 0.384
0.404MetTrp: 0.404 ± 0.253
0.809MetTyr: 0.809 ± 0.332
0.0MetXaa: 0.0 ± 0.0
Asn
3.033AsnAla: 3.033 ± 0.987
1.213AsnCys: 1.213 ± 0.553
3.236AsnAsp: 3.236 ± 0.808
3.033AsnGlu: 3.033 ± 0.97
1.213AsnPhe: 1.213 ± 0.435
2.427AsnGly: 2.427 ± 0.474
1.416AsnHis: 1.416 ± 0.289
3.033AsnIle: 3.033 ± 1.016
2.427AsnLys: 2.427 ± 1.219
6.067AsnLeu: 6.067 ± 0.839
0.607AsnMet: 0.607 ± 0.558
1.416AsnAsn: 1.416 ± 0.88
5.258AsnPro: 5.258 ± 0.964
2.427AsnGln: 2.427 ± 0.938
2.022AsnArg: 2.022 ± 0.694
3.64AsnSer: 3.64 ± 0.512
3.438AsnThr: 3.438 ± 0.936
1.011AsnVal: 1.011 ± 0.408
0.809AsnTrp: 0.809 ± 0.332
1.618AsnTyr: 1.618 ± 0.416
0.0AsnXaa: 0.0 ± 0.0
Pro
3.438ProAla: 3.438 ± 0.525
0.404ProCys: 0.404 ± 0.198
1.82ProAsp: 1.82 ± 0.751
3.64ProGlu: 3.64 ± 0.674
0.607ProPhe: 0.607 ± 0.278
2.427ProGly: 2.427 ± 1.109
1.416ProHis: 1.416 ± 0.338
5.056ProIle: 5.056 ± 1.255
2.831ProLys: 2.831 ± 0.471
6.067ProLeu: 6.067 ± 1.261
1.011ProMet: 1.011 ± 0.67
1.416ProAsn: 1.416 ± 0.673
1.213ProPro: 1.213 ± 0.365
2.022ProGln: 2.022 ± 0.394
3.236ProArg: 3.236 ± 0.981
5.258ProSer: 5.258 ± 1.269
2.831ProThr: 2.831 ± 1.148
1.416ProVal: 1.416 ± 0.356
0.0ProTrp: 0.0 ± 0.0
1.82ProTyr: 1.82 ± 0.294
0.0ProXaa: 0.0 ± 0.0
Gln
2.427GlnAla: 2.427 ± 1.093
0.809GlnCys: 0.809 ± 0.5
2.831GlnAsp: 2.831 ± 0.623
1.618GlnGlu: 1.618 ± 0.631
2.022GlnPhe: 2.022 ± 0.641
3.033GlnGly: 3.033 ± 0.965
0.809GlnHis: 0.809 ± 0.311
5.056GlnIle: 5.056 ± 1.175
1.011GlnLys: 1.011 ± 0.324
5.46GlnLeu: 5.46 ± 0.461
0.607GlnMet: 0.607 ± 0.259
2.022GlnAsn: 2.022 ± 0.686
2.224GlnPro: 2.224 ± 1.283
2.427GlnGln: 2.427 ± 1.184
2.629GlnArg: 2.629 ± 0.496
3.033GlnSer: 3.033 ± 1.001
1.82GlnThr: 1.82 ± 0.902
1.82GlnVal: 1.82 ± 0.725
0.202GlnTrp: 0.202 ± 0.124
1.213GlnTyr: 1.213 ± 0.794
0.0GlnXaa: 0.0 ± 0.0
Arg
4.044ArgAla: 4.044 ± 1.823
1.213ArgCys: 1.213 ± 0.29
1.82ArgAsp: 1.82 ± 0.713
3.033ArgGlu: 3.033 ± 0.805
2.629ArgPhe: 2.629 ± 0.814
2.629ArgGly: 2.629 ± 0.623
2.022ArgHis: 2.022 ± 0.675
4.044ArgIle: 4.044 ± 1.026
1.82ArgLys: 1.82 ± 0.725
5.865ArgLeu: 5.865 ± 0.534
1.618ArgMet: 1.618 ± 0.447
2.022ArgAsn: 2.022 ± 0.394
1.213ArgPro: 1.213 ± 0.555
2.224ArgGln: 2.224 ± 0.548
3.64ArgArg: 3.64 ± 1.32
3.842ArgSer: 3.842 ± 0.524
1.82ArgThr: 1.82 ± 0.641
4.247ArgVal: 4.247 ± 0.968
0.607ArgTrp: 0.607 ± 0.471
1.416ArgTyr: 1.416 ± 0.632
0.0ArgXaa: 0.0 ± 0.0
Ser
4.044SerAla: 4.044 ± 0.638
2.224SerCys: 2.224 ± 0.826
4.044SerAsp: 4.044 ± 0.504
4.853SerGlu: 4.853 ± 1.209
2.427SerPhe: 2.427 ± 0.668
5.46SerGly: 5.46 ± 0.766
1.213SerHis: 1.213 ± 0.365
8.493SerIle: 8.493 ± 2.162
4.247SerLys: 4.247 ± 1.97
10.92SerLeu: 10.92 ± 0.811
2.022SerMet: 2.022 ± 0.235
3.438SerAsn: 3.438 ± 1.07
2.831SerPro: 2.831 ± 0.731
4.651SerGln: 4.651 ± 0.97
4.044SerArg: 4.044 ± 0.927
8.696SerSer: 8.696 ± 1.497
7.482SerThr: 7.482 ± 1.075
6.471SerVal: 6.471 ± 0.735
1.416SerTrp: 1.416 ± 0.484
3.842SerTyr: 3.842 ± 1.125
0.0SerXaa: 0.0 ± 0.0
Thr
5.056ThrAla: 5.056 ± 1.935
1.618ThrCys: 1.618 ± 0.431
3.236ThrAsp: 3.236 ± 0.945
3.033ThrGlu: 3.033 ± 0.968
1.011ThrPhe: 1.011 ± 0.441
2.022ThrGly: 2.022 ± 0.811
0.607ThrHis: 0.607 ± 0.236
6.471ThrIle: 6.471 ± 0.769
3.033ThrLys: 3.033 ± 0.407
6.471ThrLeu: 6.471 ± 1.316
1.618ThrMet: 1.618 ± 0.269
3.236ThrAsn: 3.236 ± 1.038
4.449ThrPro: 4.449 ± 0.694
3.438ThrGln: 3.438 ± 1.697
3.033ThrArg: 3.033 ± 0.629
5.662ThrSer: 5.662 ± 0.954
6.876ThrThr: 6.876 ± 1.304
3.842ThrVal: 3.842 ± 1.296
0.809ThrTrp: 0.809 ± 0.359
1.416ThrTyr: 1.416 ± 0.469
0.0ThrXaa: 0.0 ± 0.0
Val
3.236ValAla: 3.236 ± 1.235
1.416ValCys: 1.416 ± 0.64
1.82ValAsp: 1.82 ± 0.638
2.022ValGlu: 2.022 ± 0.457
1.618ValPhe: 1.618 ± 0.556
4.449ValGly: 4.449 ± 0.698
1.416ValHis: 1.416 ± 0.426
2.831ValIle: 2.831 ± 0.738
3.236ValLys: 3.236 ± 0.78
5.662ValLeu: 5.662 ± 1.222
1.618ValMet: 1.618 ± 0.653
3.438ValAsn: 3.438 ± 1.396
2.224ValPro: 2.224 ± 0.341
3.033ValGln: 3.033 ± 1.025
2.629ValArg: 2.629 ± 0.374
4.853ValSer: 4.853 ± 0.949
3.438ValThr: 3.438 ± 0.829
4.247ValVal: 4.247 ± 0.855
0.404ValTrp: 0.404 ± 0.376
2.629ValTyr: 2.629 ± 0.505
0.0ValXaa: 0.0 ± 0.0
Trp
0.404TrpAla: 0.404 ± 0.18
0.404TrpCys: 0.404 ± 0.346
0.202TrpAsp: 0.202 ± 0.124
1.011TrpGlu: 1.011 ± 0.335
0.404TrpPhe: 0.404 ± 0.18
0.607TrpGly: 0.607 ± 0.311
0.607TrpHis: 0.607 ± 0.301
1.213TrpIle: 1.213 ± 0.398
0.607TrpLys: 0.607 ± 0.239
0.809TrpLeu: 0.809 ± 0.345
0.0TrpMet: 0.0 ± 0.0
0.404TrpAsn: 0.404 ± 0.235
0.607TrpPro: 0.607 ± 0.358
0.202TrpGln: 0.202 ± 0.124
0.404TrpArg: 0.404 ± 0.18
0.607TrpSer: 0.607 ± 0.29
0.809TrpThr: 0.809 ± 0.445
0.607TrpVal: 0.607 ± 0.259
0.202TrpTrp: 0.202 ± 0.198
0.607TrpTyr: 0.607 ± 0.371
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.618TyrAla: 1.618 ± 0.517
1.213TyrCys: 1.213 ± 0.384
1.618TyrAsp: 1.618 ± 0.453
0.607TyrGlu: 0.607 ± 0.371
0.607TyrPhe: 0.607 ± 0.236
1.416TyrGly: 1.416 ± 0.481
0.404TyrHis: 0.404 ± 0.248
3.236TyrIle: 3.236 ± 0.834
1.82TyrLys: 1.82 ± 0.429
3.64TyrLeu: 3.64 ± 0.995
0.202TyrMet: 0.202 ± 0.252
1.213TyrAsn: 1.213 ± 0.533
1.416TyrPro: 1.416 ± 0.523
1.618TyrGln: 1.618 ± 0.516
2.022TyrArg: 2.022 ± 0.517
4.449TyrSer: 4.449 ± 0.681
2.224TyrThr: 2.224 ± 0.763
2.224TyrVal: 2.224 ± 0.492
0.404TyrTrp: 0.404 ± 0.248
0.607TyrTyr: 0.607 ± 0.471
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4946 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski