Amino acid dipepetide frequency for Fowl aviadenovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.929AlaAla: 6.929 ± 1.023
1.168AlaCys: 1.168 ± 0.424
4.593AlaAsp: 4.593 ± 0.585
4.982AlaGlu: 4.982 ± 0.827
2.647AlaPhe: 2.647 ± 0.318
4.671AlaGly: 4.671 ± 0.74
1.479AlaHis: 1.479 ± 0.316
4.438AlaIle: 4.438 ± 0.657
2.569AlaLys: 2.569 ± 0.424
7.629AlaLeu: 7.629 ± 0.972
1.868AlaMet: 1.868 ± 0.722
3.114AlaAsn: 3.114 ± 0.38
6.072AlaPro: 6.072 ± 0.797
2.958AlaGln: 2.958 ± 0.514
4.282AlaArg: 4.282 ± 0.681
5.917AlaSer: 5.917 ± 0.744
4.671AlaThr: 4.671 ± 0.666
5.294AlaVal: 5.294 ± 0.646
0.856AlaTrp: 0.856 ± 0.304
3.503AlaTyr: 3.503 ± 0.432
0.0AlaXaa: 0.0 ± 0.0
Cys
1.168CysAla: 1.168 ± 0.321
0.467CysCys: 0.467 ± 0.224
1.168CysAsp: 1.168 ± 0.344
0.545CysGlu: 0.545 ± 0.266
1.012CysPhe: 1.012 ± 0.302
1.479CysGly: 1.479 ± 0.356
0.701CysHis: 0.701 ± 0.274
0.701CysIle: 0.701 ± 0.269
0.779CysLys: 0.779 ± 0.309
1.09CysLeu: 1.09 ± 0.36
0.623CysMet: 0.623 ± 0.259
0.623CysAsn: 0.623 ± 0.265
1.168CysPro: 1.168 ± 0.319
0.856CysGln: 0.856 ± 0.267
1.401CysArg: 1.401 ± 0.409
1.246CysSer: 1.246 ± 0.265
1.323CysThr: 1.323 ± 0.428
1.168CysVal: 1.168 ± 0.424
0.311CysTrp: 0.311 ± 0.128
0.779CysTyr: 0.779 ± 0.198
0.0CysXaa: 0.0 ± 0.0
Asp
4.126AspAla: 4.126 ± 0.562
0.779AspCys: 0.779 ± 0.237
2.88AspAsp: 2.88 ± 0.52
3.581AspGlu: 3.581 ± 0.638
2.958AspPhe: 2.958 ± 0.42
3.97AspGly: 3.97 ± 0.486
1.401AspHis: 1.401 ± 0.271
2.491AspIle: 2.491 ± 0.421
1.946AspLys: 1.946 ± 0.479
4.282AspLeu: 4.282 ± 0.558
1.168AspMet: 1.168 ± 0.281
1.557AspAsn: 1.557 ± 0.444
4.982AspPro: 4.982 ± 0.622
1.946AspGln: 1.946 ± 0.383
3.97AspArg: 3.97 ± 0.598
4.593AspSer: 4.593 ± 0.55
3.192AspThr: 3.192 ± 0.677
2.88AspVal: 2.88 ± 0.533
0.701AspTrp: 0.701 ± 0.172
1.946AspTyr: 1.946 ± 0.358
0.0AspXaa: 0.0 ± 0.0
Glu
4.905GluAla: 4.905 ± 0.746
0.856GluCys: 0.856 ± 0.276
4.048GluAsp: 4.048 ± 0.588
8.641GluGlu: 8.641 ± 1.881
1.635GluPhe: 1.635 ± 0.408
3.737GluGly: 3.737 ± 0.547
1.479GluHis: 1.479 ± 0.357
2.491GluIle: 2.491 ± 0.352
1.946GluLys: 1.946 ± 0.466
5.761GluLeu: 5.761 ± 0.641
1.246GluMet: 1.246 ± 0.299
3.581GluAsn: 3.581 ± 0.644
2.569GluPro: 2.569 ± 0.385
2.024GluGln: 2.024 ± 0.504
3.581GluArg: 3.581 ± 0.724
4.593GluSer: 4.593 ± 0.698
3.893GluThr: 3.893 ± 0.521
3.036GluVal: 3.036 ± 0.461
0.934GluTrp: 0.934 ± 0.249
1.791GluTyr: 1.791 ± 0.342
0.0GluXaa: 0.0 ± 0.0
Phe
3.036PheAla: 3.036 ± 0.47
0.545PheCys: 0.545 ± 0.257
2.88PheAsp: 2.88 ± 0.615
2.413PheGlu: 2.413 ± 0.445
1.635PhePhe: 1.635 ± 0.285
1.557PheGly: 1.557 ± 0.297
1.713PheHis: 1.713 ± 0.348
0.934PheIle: 0.934 ± 0.282
2.024PheLys: 2.024 ± 0.35
4.515PheLeu: 4.515 ± 0.702
1.012PheMet: 1.012 ± 0.279
2.102PheAsn: 2.102 ± 0.408
2.491PhePro: 2.491 ± 0.466
0.856PheGln: 0.856 ± 0.264
3.27PheArg: 3.27 ± 0.396
2.18PheSer: 2.18 ± 0.411
2.413PheThr: 2.413 ± 0.467
3.425PheVal: 3.425 ± 0.569
1.168PheTrp: 1.168 ± 0.276
1.713PheTyr: 1.713 ± 0.295
0.0PheXaa: 0.0 ± 0.0
Gly
6.773GlyAla: 6.773 ± 0.862
0.856GlyCys: 0.856 ± 0.299
2.958GlyAsp: 2.958 ± 0.631
4.048GlyGlu: 4.048 ± 0.748
2.336GlyPhe: 2.336 ± 0.352
5.995GlyGly: 5.995 ± 0.857
1.09GlyHis: 1.09 ± 0.325
2.102GlyIle: 2.102 ± 0.458
1.868GlyLys: 1.868 ± 0.453
4.749GlyLeu: 4.749 ± 0.794
1.479GlyMet: 1.479 ± 0.311
2.258GlyAsn: 2.258 ± 0.462
2.725GlyPro: 2.725 ± 0.515
1.323GlyGln: 1.323 ± 0.359
4.282GlyArg: 4.282 ± 0.556
4.048GlySer: 4.048 ± 0.581
3.659GlyThr: 3.659 ± 0.593
5.372GlyVal: 5.372 ± 0.802
1.246GlyTrp: 1.246 ± 0.27
2.725GlyTyr: 2.725 ± 0.421
0.0GlyXaa: 0.0 ± 0.0
His
1.323HisAla: 1.323 ± 0.257
0.623HisCys: 0.623 ± 0.256
1.401HisAsp: 1.401 ± 0.311
1.168HisGlu: 1.168 ± 0.333
0.623HisPhe: 0.623 ± 0.228
1.479HisGly: 1.479 ± 0.34
0.934HisHis: 0.934 ± 0.249
1.09HisIle: 1.09 ± 0.307
0.389HisLys: 0.389 ± 0.163
2.102HisLeu: 2.102 ± 0.482
0.311HisMet: 0.311 ± 0.152
1.246HisAsn: 1.246 ± 0.266
1.713HisPro: 1.713 ± 0.441
0.934HisGln: 0.934 ± 0.326
2.258HisArg: 2.258 ± 0.394
1.09HisSer: 1.09 ± 0.293
1.168HisThr: 1.168 ± 0.304
1.635HisVal: 1.635 ± 0.424
0.234HisTrp: 0.234 ± 0.14
0.856HisTyr: 0.856 ± 0.223
0.0HisXaa: 0.0 ± 0.0
Ile
3.97IleAla: 3.97 ± 0.609
0.856IleCys: 0.856 ± 0.289
2.024IleAsp: 2.024 ± 0.339
2.024IleGlu: 2.024 ± 0.374
1.479IlePhe: 1.479 ± 0.319
2.102IleGly: 2.102 ± 0.385
0.856IleHis: 0.856 ± 0.24
1.635IleIle: 1.635 ± 0.357
1.09IleLys: 1.09 ± 0.325
3.893IleLeu: 3.893 ± 0.592
0.779IleMet: 0.779 ± 0.29
1.791IleAsn: 1.791 ± 0.394
3.036IlePro: 3.036 ± 0.435
1.323IleGln: 1.323 ± 0.316
3.192IleArg: 3.192 ± 0.429
2.958IleSer: 2.958 ± 0.453
2.725IleThr: 2.725 ± 0.607
2.725IleVal: 2.725 ± 0.481
0.467IleTrp: 0.467 ± 0.223
1.635IleTyr: 1.635 ± 0.337
0.0IleXaa: 0.0 ± 0.0
Lys
2.102LysAla: 2.102 ± 0.486
0.779LysCys: 0.779 ± 0.299
1.635LysAsp: 1.635 ± 0.32
2.336LysGlu: 2.336 ± 0.495
2.024LysPhe: 2.024 ± 0.472
2.024LysGly: 2.024 ± 0.524
0.389LysHis: 0.389 ± 0.168
1.635LysIle: 1.635 ± 0.278
2.102LysLys: 2.102 ± 0.517
3.737LysLeu: 3.737 ± 0.622
1.012LysMet: 1.012 ± 0.259
1.713LysAsn: 1.713 ± 0.342
1.791LysPro: 1.791 ± 0.35
1.012LysGln: 1.012 ± 0.263
3.815LysArg: 3.815 ± 0.735
1.479LysSer: 1.479 ± 0.379
2.958LysThr: 2.958 ± 0.46
1.868LysVal: 1.868 ± 0.357
0.545LysTrp: 0.545 ± 0.187
1.946LysTyr: 1.946 ± 0.463
0.0LysXaa: 0.0 ± 0.0
Leu
6.384LeuAla: 6.384 ± 0.498
2.024LeuCys: 2.024 ± 0.477
4.204LeuAsp: 4.204 ± 0.54
4.204LeuGlu: 4.204 ± 0.586
3.893LeuPhe: 3.893 ± 0.585
4.36LeuGly: 4.36 ± 0.525
2.413LeuHis: 2.413 ± 0.579
3.114LeuIle: 3.114 ± 0.484
3.581LeuLys: 3.581 ± 0.558
7.863LeuLeu: 7.863 ± 0.683
2.336LeuMet: 2.336 ± 0.419
3.815LeuAsn: 3.815 ± 0.48
5.216LeuPro: 5.216 ± 0.447
4.204LeuGln: 4.204 ± 0.446
6.851LeuArg: 6.851 ± 1.004
6.617LeuSer: 6.617 ± 0.57
6.929LeuThr: 6.929 ± 0.872
4.671LeuVal: 4.671 ± 0.689
1.401LeuTrp: 1.401 ± 0.263
3.581LeuTyr: 3.581 ± 0.6
0.0LeuXaa: 0.0 ± 0.0
Met
2.88MetAla: 2.88 ± 0.576
0.234MetCys: 0.234 ± 0.135
1.401MetAsp: 1.401 ± 0.319
1.168MetGlu: 1.168 ± 0.305
1.012MetPhe: 1.012 ± 0.303
1.323MetGly: 1.323 ± 0.335
0.701MetHis: 0.701 ± 0.236
0.779MetIle: 0.779 ± 0.287
1.09MetLys: 1.09 ± 0.298
2.258MetLeu: 2.258 ± 0.328
0.467MetMet: 0.467 ± 0.178
0.779MetAsn: 0.779 ± 0.196
1.246MetPro: 1.246 ± 0.252
1.09MetGln: 1.09 ± 0.229
1.713MetArg: 1.713 ± 0.401
1.791MetSer: 1.791 ± 0.344
1.09MetThr: 1.09 ± 0.312
1.401MetVal: 1.401 ± 0.319
0.156MetTrp: 0.156 ± 0.104
1.012MetTyr: 1.012 ± 0.293
0.0MetXaa: 0.0 ± 0.0
Asn
3.503AsnAla: 3.503 ± 0.539
1.09AsnCys: 1.09 ± 0.308
2.102AsnAsp: 2.102 ± 0.392
1.868AsnGlu: 1.868 ± 0.541
1.557AsnPhe: 1.557 ± 0.52
2.336AsnGly: 2.336 ± 0.525
0.779AsnHis: 0.779 ± 0.199
1.635AsnIle: 1.635 ± 0.45
1.791AsnLys: 1.791 ± 0.413
3.27AsnLeu: 3.27 ± 0.616
0.701AsnMet: 0.701 ± 0.306
1.868AsnAsn: 1.868 ± 0.496
3.893AsnPro: 3.893 ± 0.475
1.323AsnGln: 1.323 ± 0.384
2.958AsnArg: 2.958 ± 0.536
2.958AsnSer: 2.958 ± 0.643
2.491AsnThr: 2.491 ± 0.418
3.581AsnVal: 3.581 ± 0.585
0.701AsnTrp: 0.701 ± 0.296
1.868AsnTyr: 1.868 ± 0.427
0.0AsnXaa: 0.0 ± 0.0
Pro
5.527ProAla: 5.527 ± 0.934
0.856ProCys: 0.856 ± 0.246
3.348ProAsp: 3.348 ± 0.349
4.749ProGlu: 4.749 ± 0.748
3.114ProPhe: 3.114 ± 0.483
2.258ProGly: 2.258 ± 0.352
1.246ProHis: 1.246 ± 0.368
2.491ProIle: 2.491 ± 0.526
1.946ProLys: 1.946 ± 0.53
5.294ProLeu: 5.294 ± 0.689
1.323ProMet: 1.323 ± 0.403
3.036ProAsn: 3.036 ± 0.496
6.384ProPro: 6.384 ± 0.907
2.18ProGln: 2.18 ± 0.469
3.893ProArg: 3.893 ± 0.547
5.839ProSer: 5.839 ± 0.69
4.204ProThr: 4.204 ± 0.646
4.282ProVal: 4.282 ± 0.544
0.467ProTrp: 0.467 ± 0.158
3.036ProTyr: 3.036 ± 0.538
0.0ProXaa: 0.0 ± 0.0
Gln
2.725GlnAla: 2.725 ± 0.546
0.389GlnCys: 0.389 ± 0.178
1.791GlnAsp: 1.791 ± 0.369
2.18GlnGlu: 2.18 ± 0.511
1.168GlnPhe: 1.168 ± 0.318
1.791GlnGly: 1.791 ± 0.354
0.779GlnHis: 0.779 ± 0.349
1.323GlnIle: 1.323 ± 0.283
1.635GlnLys: 1.635 ± 0.318
3.659GlnLeu: 3.659 ± 0.531
1.323GlnMet: 1.323 ± 0.323
1.946GlnAsn: 1.946 ± 0.516
1.946GlnPro: 1.946 ± 0.381
2.102GlnGln: 2.102 ± 0.622
2.336GlnArg: 2.336 ± 0.475
2.102GlnSer: 2.102 ± 0.434
2.336GlnThr: 2.336 ± 0.516
2.102GlnVal: 2.102 ± 0.416
0.311GlnTrp: 0.311 ± 0.144
2.024GlnTyr: 2.024 ± 0.391
0.0GlnXaa: 0.0 ± 0.0
Arg
4.905ArgAla: 4.905 ± 0.768
1.168ArgCys: 1.168 ± 0.409
3.503ArgAsp: 3.503 ± 0.583
4.048ArgGlu: 4.048 ± 0.662
3.036ArgPhe: 3.036 ± 0.363
4.36ArgGly: 4.36 ± 0.809
2.18ArgHis: 2.18 ± 0.56
2.958ArgIle: 2.958 ± 0.48
3.114ArgLys: 3.114 ± 0.633
6.228ArgLeu: 6.228 ± 0.88
2.102ArgMet: 2.102 ± 0.368
3.036ArgAsn: 3.036 ± 0.676
4.126ArgPro: 4.126 ± 0.715
3.036ArgGln: 3.036 ± 0.397
8.33ArgArg: 8.33 ± 1.673
5.527ArgSer: 5.527 ± 0.731
3.659ArgThr: 3.659 ± 0.506
4.827ArgVal: 4.827 ± 0.629
0.934ArgTrp: 0.934 ± 0.212
2.647ArgTyr: 2.647 ± 0.444
0.0ArgXaa: 0.0 ± 0.0
Ser
4.905SerAla: 4.905 ± 0.729
1.246SerCys: 1.246 ± 0.333
5.527SerAsp: 5.527 ± 0.896
4.905SerGlu: 4.905 ± 0.657
2.725SerPhe: 2.725 ± 0.517
6.851SerGly: 6.851 ± 0.92
1.012SerHis: 1.012 ± 0.384
2.958SerIle: 2.958 ± 0.459
2.958SerLys: 2.958 ± 0.538
5.527SerLeu: 5.527 ± 0.731
1.791SerMet: 1.791 ± 0.414
2.491SerAsn: 2.491 ± 0.691
4.204SerPro: 4.204 ± 0.608
2.336SerGln: 2.336 ± 0.491
5.761SerArg: 5.761 ± 0.683
6.228SerSer: 6.228 ± 1.174
4.126SerThr: 4.126 ± 0.538
3.659SerVal: 3.659 ± 0.625
0.934SerTrp: 0.934 ± 0.3
2.024SerTyr: 2.024 ± 0.425
0.0SerXaa: 0.0 ± 0.0
Thr
6.462ThrAla: 6.462 ± 0.933
1.557ThrCys: 1.557 ± 0.391
2.803ThrAsp: 2.803 ± 0.558
3.97ThrGlu: 3.97 ± 0.469
2.569ThrPhe: 2.569 ± 0.517
4.827ThrGly: 4.827 ± 0.896
0.934ThrHis: 0.934 ± 0.308
2.88ThrIle: 2.88 ± 0.372
1.09ThrLys: 1.09 ± 0.258
5.372ThrLeu: 5.372 ± 0.693
1.012ThrMet: 1.012 ± 0.212
2.491ThrAsn: 2.491 ± 0.507
3.659ThrPro: 3.659 ± 0.613
2.024ThrGln: 2.024 ± 0.432
3.97ThrArg: 3.97 ± 0.648
3.503ThrSer: 3.503 ± 0.692
3.425ThrThr: 3.425 ± 0.572
4.749ThrVal: 4.749 ± 0.588
0.545ThrTrp: 0.545 ± 0.224
2.725ThrTyr: 2.725 ± 0.618
0.0ThrXaa: 0.0 ± 0.0
Val
4.671ValAla: 4.671 ± 0.734
1.401ValCys: 1.401 ± 0.297
3.425ValAsp: 3.425 ± 0.599
3.503ValGlu: 3.503 ± 0.548
3.348ValPhe: 3.348 ± 0.59
3.737ValGly: 3.737 ± 0.579
1.168ValHis: 1.168 ± 0.279
3.192ValIle: 3.192 ± 0.426
2.491ValLys: 2.491 ± 0.448
6.228ValLeu: 6.228 ± 0.707
1.246ValMet: 1.246 ± 0.299
2.569ValAsn: 2.569 ± 0.617
4.749ValPro: 4.749 ± 0.604
2.88ValGln: 2.88 ± 0.619
4.126ValArg: 4.126 ± 0.512
5.138ValSer: 5.138 ± 0.684
3.659ValThr: 3.659 ± 0.652
4.204ValVal: 4.204 ± 0.627
0.701ValTrp: 0.701 ± 0.22
2.413ValTyr: 2.413 ± 0.416
0.0ValXaa: 0.0 ± 0.0
Trp
0.701TrpAla: 0.701 ± 0.303
0.467TrpCys: 0.467 ± 0.222
0.856TrpAsp: 0.856 ± 0.25
0.623TrpGlu: 0.623 ± 0.153
0.623TrpPhe: 0.623 ± 0.227
0.856TrpGly: 0.856 ± 0.249
0.234TrpHis: 0.234 ± 0.124
0.545TrpIle: 0.545 ± 0.194
0.545TrpLys: 0.545 ± 0.266
1.246TrpLeu: 1.246 ± 0.307
0.156TrpMet: 0.156 ± 0.141
0.779TrpAsn: 0.779 ± 0.247
0.467TrpPro: 0.467 ± 0.345
0.545TrpGln: 0.545 ± 0.248
1.012TrpArg: 1.012 ± 0.241
1.012TrpSer: 1.012 ± 0.256
0.779TrpThr: 0.779 ± 0.242
1.09TrpVal: 1.09 ± 0.341
0.078TrpTrp: 0.078 ± 0.083
0.779TrpTyr: 0.779 ± 0.231
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.647TyrAla: 2.647 ± 0.387
1.246TyrCys: 1.246 ± 0.296
2.803TyrAsp: 2.803 ± 0.647
1.791TyrGlu: 1.791 ± 0.371
2.491TyrPhe: 2.491 ± 0.383
2.18TyrGly: 2.18 ± 0.412
1.09TyrHis: 1.09 ± 0.252
1.168TyrIle: 1.168 ± 0.28
1.946TyrLys: 1.946 ± 0.472
2.958TyrLeu: 2.958 ± 0.541
1.557TyrMet: 1.557 ± 0.41
1.479TyrAsn: 1.479 ± 0.339
3.036TyrPro: 3.036 ± 0.421
1.012TyrGln: 1.012 ± 0.246
2.725TyrArg: 2.725 ± 0.447
3.348TyrSer: 3.348 ± 0.528
1.868TyrThr: 1.868 ± 0.437
2.88TyrVal: 2.88 ± 0.442
0.779TyrTrp: 0.779 ± 0.236
1.168TyrTyr: 1.168 ± 0.205
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37 proteins (12846 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski