Amino acid dipepetide frequency for Alfalfa associated nucleorhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.195AlaAla: 1.195 ± 1.097
0.0AlaCys: 0.0 ± 0.0
1.673AlaAsp: 1.673 ± 0.802
3.346AlaGlu: 3.346 ± 1.373
2.39AlaPhe: 2.39 ± 0.575
2.39AlaGly: 2.39 ± 0.767
0.0AlaHis: 0.0 ± 0.0
3.585AlaIle: 3.585 ± 1.208
3.585AlaLys: 3.585 ± 1.357
3.824AlaLeu: 3.824 ± 1.386
0.478AlaMet: 0.478 ± 0.261
2.151AlaAsn: 2.151 ± 0.895
1.912AlaPro: 1.912 ± 1.19
0.478AlaGln: 0.478 ± 0.338
3.107AlaArg: 3.107 ± 1.118
4.063AlaSer: 4.063 ± 0.979
2.629AlaThr: 2.629 ± 0.402
3.107AlaVal: 3.107 ± 0.518
0.956AlaTrp: 0.956 ± 0.794
2.629AlaTyr: 2.629 ± 0.971
0.0AlaXaa: 0.0 ± 0.0
Cys
1.195CysAla: 1.195 ± 0.525
0.239CysCys: 0.239 ± 0.155
0.956CysAsp: 0.956 ± 0.333
0.478CysGlu: 0.478 ± 0.397
0.956CysPhe: 0.956 ± 0.667
1.195CysGly: 1.195 ± 0.774
0.478CysHis: 0.478 ± 0.274
1.434CysIle: 1.434 ± 0.487
0.956CysLys: 0.956 ± 0.432
1.912CysLeu: 1.912 ± 0.839
0.956CysMet: 0.956 ± 0.62
0.956CysAsn: 0.956 ± 0.502
1.434CysPro: 1.434 ± 0.425
0.956CysGln: 0.956 ± 0.564
0.956CysArg: 0.956 ± 0.454
2.39CysSer: 2.39 ± 0.617
0.478CysThr: 0.478 ± 0.759
1.195CysVal: 1.195 ± 0.524
0.0CysTrp: 0.0 ± 0.0
0.717CysTyr: 0.717 ± 0.32
0.0CysXaa: 0.0 ± 0.0
Asp
2.39AspAla: 2.39 ± 1.124
0.478AspCys: 0.478 ± 0.526
5.258AspAsp: 5.258 ± 1.77
4.302AspGlu: 4.302 ± 0.833
1.912AspPhe: 1.912 ± 0.712
2.868AspGly: 2.868 ± 0.779
2.868AspHis: 2.868 ± 1.399
7.17AspIle: 7.17 ± 1.974
5.258AspLys: 5.258 ± 0.802
5.975AspLeu: 5.975 ± 0.997
2.629AspMet: 2.629 ± 0.659
2.868AspAsn: 2.868 ± 1.111
2.629AspPro: 2.629 ± 1.012
1.912AspGln: 1.912 ± 1.095
3.346AspArg: 3.346 ± 0.916
5.497AspSer: 5.497 ± 1.685
1.912AspThr: 1.912 ± 0.704
3.346AspVal: 3.346 ± 0.547
0.717AspTrp: 0.717 ± 0.302
1.912AspTyr: 1.912 ± 0.71
0.0AspXaa: 0.0 ± 0.0
Glu
2.151GluAla: 2.151 ± 0.799
0.956GluCys: 0.956 ± 0.312
8.604GluAsp: 8.604 ± 1.301
5.258GluGlu: 5.258 ± 1.194
1.912GluPhe: 1.912 ± 0.693
3.824GluGly: 3.824 ± 0.577
2.39GluHis: 2.39 ± 0.733
5.019GluIle: 5.019 ± 0.381
5.736GluLys: 5.736 ± 1.38
5.019GluLeu: 5.019 ± 1.35
2.629GluMet: 2.629 ± 0.706
2.868GluAsn: 2.868 ± 0.454
2.629GluPro: 2.629 ± 1.847
1.912GluGln: 1.912 ± 0.806
2.39GluArg: 2.39 ± 0.575
4.78GluSer: 4.78 ± 1.377
4.063GluThr: 4.063 ± 1.122
2.629GluVal: 2.629 ± 1.746
0.956GluTrp: 0.956 ± 0.606
2.151GluTyr: 2.151 ± 0.76
0.0GluXaa: 0.0 ± 0.0
Phe
0.478PheAla: 0.478 ± 0.31
0.239PheCys: 0.239 ± 0.155
2.39PheAsp: 2.39 ± 0.568
1.195PheGlu: 1.195 ± 0.481
1.434PhePhe: 1.434 ± 0.425
1.673PheGly: 1.673 ± 0.829
0.717PheHis: 0.717 ± 0.465
2.151PheIle: 2.151 ± 0.726
3.585PheLys: 3.585 ± 1.755
3.585PheLeu: 3.585 ± 0.561
1.673PheMet: 1.673 ± 0.502
1.912PheAsn: 1.912 ± 0.775
0.956PhePro: 0.956 ± 0.419
0.717PheGln: 0.717 ± 0.385
1.912PheArg: 1.912 ± 0.509
4.541PheSer: 4.541 ± 1.169
1.195PheThr: 1.195 ± 0.653
1.673PheVal: 1.673 ± 0.819
0.239PheTrp: 0.239 ± 0.38
0.717PheTyr: 0.717 ± 0.465
0.0PheXaa: 0.0 ± 0.0
Gly
1.912GlyAla: 1.912 ± 0.519
0.956GlyCys: 0.956 ± 0.432
3.585GlyAsp: 3.585 ± 0.762
4.541GlyGlu: 4.541 ± 0.882
2.868GlyPhe: 2.868 ± 0.828
2.629GlyGly: 2.629 ± 0.865
1.195GlyHis: 1.195 ± 0.466
4.302GlyIle: 4.302 ± 0.977
4.063GlyLys: 4.063 ± 1.039
4.063GlyLeu: 4.063 ± 0.896
2.151GlyMet: 2.151 ± 1.271
1.434GlyAsn: 1.434 ± 0.53
0.478GlyPro: 0.478 ± 0.256
0.717GlyGln: 0.717 ± 0.488
0.478GlyArg: 0.478 ± 0.274
4.063GlySer: 4.063 ± 1.24
3.824GlyThr: 3.824 ± 0.796
2.629GlyVal: 2.629 ± 1.29
0.717GlyTrp: 0.717 ± 0.45
1.912GlyTyr: 1.912 ± 0.473
0.0GlyXaa: 0.0 ± 0.0
His
1.434HisAla: 1.434 ± 0.713
0.717HisCys: 0.717 ± 0.346
4.063HisAsp: 4.063 ± 0.958
2.151HisGlu: 2.151 ± 0.675
1.195HisPhe: 1.195 ± 0.565
2.39HisGly: 2.39 ± 1.023
0.956HisHis: 0.956 ± 0.555
2.151HisIle: 2.151 ± 1.054
2.151HisLys: 2.151 ± 0.647
1.195HisLeu: 1.195 ± 0.358
0.478HisMet: 0.478 ± 0.269
0.478HisAsn: 0.478 ± 0.256
1.195HisPro: 1.195 ± 0.384
0.0HisGln: 0.0 ± 0.0
0.478HisArg: 0.478 ± 0.269
2.151HisSer: 2.151 ± 0.489
1.434HisThr: 1.434 ± 0.501
0.717HisVal: 0.717 ± 0.511
0.478HisTrp: 0.478 ± 0.256
1.195HisTyr: 1.195 ± 0.684
0.0HisXaa: 0.0 ± 0.0
Ile
3.346IleAla: 3.346 ± 1.328
1.195IleCys: 1.195 ± 0.761
2.629IleAsp: 2.629 ± 0.64
5.736IleGlu: 5.736 ± 0.758
1.434IlePhe: 1.434 ± 0.554
4.78IleGly: 4.78 ± 1.034
3.585IleHis: 3.585 ± 0.598
6.692IleIle: 6.692 ± 0.838
7.17IleLys: 7.17 ± 1.06
6.931IleLeu: 6.931 ± 0.837
3.585IleMet: 3.585 ± 0.528
3.346IleAsn: 3.346 ± 0.507
4.302IlePro: 4.302 ± 0.741
1.673IleGln: 1.673 ± 0.668
5.736IleArg: 5.736 ± 0.486
7.409IleSer: 7.409 ± 1.555
5.736IleThr: 5.736 ± 1.089
4.063IleVal: 4.063 ± 1.289
1.195IleTrp: 1.195 ± 0.759
2.868IleTyr: 2.868 ± 0.634
0.0IleXaa: 0.0 ± 0.0
Lys
4.063LysAla: 4.063 ± 0.766
0.956LysCys: 0.956 ± 0.419
4.78LysAsp: 4.78 ± 1.377
7.887LysGlu: 7.887 ± 1.728
4.302LysPhe: 4.302 ± 1.269
3.824LysGly: 3.824 ± 0.491
0.956LysHis: 0.956 ± 0.62
8.604LysIle: 8.604 ± 1.32
7.648LysLys: 7.648 ± 1.268
7.648LysLeu: 7.648 ± 1.507
2.151LysMet: 2.151 ± 0.413
2.629LysAsn: 2.629 ± 0.865
0.717LysPro: 0.717 ± 0.66
2.151LysGln: 2.151 ± 0.919
6.692LysArg: 6.692 ± 0.529
3.346LysSer: 3.346 ± 0.963
3.107LysThr: 3.107 ± 0.863
5.975LysVal: 5.975 ± 1.996
0.717LysTrp: 0.717 ± 0.465
1.912LysTyr: 1.912 ± 0.42
0.0LysXaa: 0.0 ± 0.0
Leu
3.107LeuAla: 3.107 ± 0.762
1.434LeuCys: 1.434 ± 0.425
4.063LeuAsp: 4.063 ± 0.889
5.019LeuGlu: 5.019 ± 0.466
3.585LeuPhe: 3.585 ± 2.05
4.063LeuGly: 4.063 ± 0.382
1.195LeuHis: 1.195 ± 0.546
4.78LeuIle: 4.78 ± 0.851
4.78LeuLys: 4.78 ± 1.294
7.887LeuLeu: 7.887 ± 1.34
2.39LeuMet: 2.39 ± 0.45
5.019LeuAsn: 5.019 ± 1.039
2.868LeuPro: 2.868 ± 1.682
3.107LeuGln: 3.107 ± 0.707
3.824LeuArg: 3.824 ± 0.839
8.126LeuSer: 8.126 ± 2.048
5.258LeuThr: 5.258 ± 1.146
5.258LeuVal: 5.258 ± 0.716
1.673LeuTrp: 1.673 ± 0.503
4.541LeuTyr: 4.541 ± 1.284
0.0LeuXaa: 0.0 ± 0.0
Met
1.195MetAla: 1.195 ± 0.531
0.717MetCys: 0.717 ± 0.302
1.673MetAsp: 1.673 ± 0.493
2.151MetGlu: 2.151 ± 0.706
0.239MetPhe: 0.239 ± 0.155
1.195MetGly: 1.195 ± 0.755
0.478MetHis: 0.478 ± 0.261
3.585MetIle: 3.585 ± 0.593
3.107MetLys: 3.107 ± 0.727
0.717MetLeu: 0.717 ± 0.337
1.912MetMet: 1.912 ± 0.849
2.629MetAsn: 2.629 ± 0.576
0.956MetPro: 0.956 ± 0.416
0.478MetGln: 0.478 ± 0.675
2.868MetArg: 2.868 ± 0.589
3.585MetSer: 3.585 ± 1.266
2.629MetThr: 2.629 ± 0.84
1.434MetVal: 1.434 ± 0.357
0.717MetTrp: 0.717 ± 0.362
2.39MetTyr: 2.39 ± 0.697
0.0MetXaa: 0.0 ± 0.0
Asn
2.39AsnAla: 2.39 ± 0.613
1.912AsnCys: 1.912 ± 0.882
3.107AsnAsp: 3.107 ± 0.92
3.824AsnGlu: 3.824 ± 1.043
0.717AsnPhe: 0.717 ± 0.565
1.912AsnGly: 1.912 ± 1.404
0.956AsnHis: 0.956 ± 0.62
5.258AsnIle: 5.258 ± 0.652
5.019AsnLys: 5.019 ± 0.718
5.019AsnLeu: 5.019 ± 1.834
1.673AsnMet: 1.673 ± 0.856
2.151AsnAsn: 2.151 ± 0.859
0.478AsnPro: 0.478 ± 0.31
1.195AsnGln: 1.195 ± 0.466
1.195AsnArg: 1.195 ± 0.463
3.824AsnSer: 3.824 ± 0.828
1.912AsnThr: 1.912 ± 0.42
1.673AsnVal: 1.673 ± 0.476
0.239AsnTrp: 0.239 ± 0.155
2.39AsnTyr: 2.39 ± 0.426
0.0AsnXaa: 0.0 ± 0.0
Pro
0.478ProAla: 0.478 ± 0.759
0.956ProCys: 0.956 ± 0.877
1.912ProAsp: 1.912 ± 0.632
1.434ProGlu: 1.434 ± 0.854
1.673ProPhe: 1.673 ± 0.724
1.195ProGly: 1.195 ± 0.653
0.956ProHis: 0.956 ± 0.673
3.346ProIle: 3.346 ± 1.509
2.868ProLys: 2.868 ± 0.842
3.346ProLeu: 3.346 ± 1.341
0.478ProMet: 0.478 ± 0.31
1.434ProAsn: 1.434 ± 0.295
0.478ProPro: 0.478 ± 0.31
0.956ProGln: 0.956 ± 0.785
2.39ProArg: 2.39 ± 0.844
3.585ProSer: 3.585 ± 0.593
2.151ProThr: 2.151 ± 1.743
1.195ProVal: 1.195 ± 0.585
0.478ProTrp: 0.478 ± 0.274
4.302ProTyr: 4.302 ± 1.353
0.0ProXaa: 0.0 ± 0.0
Gln
1.434GlnAla: 1.434 ± 0.465
0.478GlnCys: 0.478 ± 0.261
2.151GlnAsp: 2.151 ± 0.894
1.912GlnGlu: 1.912 ± 0.61
0.239GlnPhe: 0.239 ± 0.277
0.956GlnGly: 0.956 ± 0.413
0.956GlnHis: 0.956 ± 0.328
3.346GlnIle: 3.346 ± 1.219
2.629GlnLys: 2.629 ± 0.818
0.717GlnLeu: 0.717 ± 0.32
0.956GlnMet: 0.956 ± 0.342
1.434GlnAsn: 1.434 ± 0.796
0.717GlnPro: 0.717 ± 0.557
0.239GlnGln: 0.239 ± 0.315
0.478GlnArg: 0.478 ± 0.622
1.673GlnSer: 1.673 ± 0.63
1.673GlnThr: 1.673 ± 0.982
1.912GlnVal: 1.912 ± 0.508
0.239GlnTrp: 0.239 ± 0.315
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.151ArgAla: 2.151 ± 0.516
1.673ArgCys: 1.673 ± 0.616
2.39ArgAsp: 2.39 ± 1.088
3.107ArgGlu: 3.107 ± 0.956
1.434ArgPhe: 1.434 ± 0.707
3.346ArgGly: 3.346 ± 1.092
0.717ArgHis: 0.717 ± 0.397
4.063ArgIle: 4.063 ± 1.037
3.107ArgLys: 3.107 ± 1.312
1.912ArgLeu: 1.912 ± 0.775
1.912ArgMet: 1.912 ± 0.794
1.912ArgAsn: 1.912 ± 0.754
0.956ArgPro: 0.956 ± 0.413
1.434ArgGln: 1.434 ± 0.352
3.107ArgArg: 3.107 ± 0.68
6.214ArgSer: 6.214 ± 2.058
3.824ArgThr: 3.824 ± 1.954
3.585ArgVal: 3.585 ± 0.973
0.956ArgTrp: 0.956 ± 0.62
2.39ArgTyr: 2.39 ± 0.574
0.0ArgXaa: 0.0 ± 0.0
Ser
5.497SerAla: 5.497 ± 1.361
2.629SerCys: 2.629 ± 0.883
5.975SerAsp: 5.975 ± 2.0
5.497SerGlu: 5.497 ± 1.304
1.673SerPhe: 1.673 ± 0.59
4.302SerGly: 4.302 ± 1.193
2.629SerHis: 2.629 ± 0.758
5.019SerIle: 5.019 ± 0.698
5.975SerLys: 5.975 ± 1.236
6.453SerLeu: 6.453 ± 1.469
1.912SerMet: 1.912 ± 0.464
5.019SerAsn: 5.019 ± 1.062
5.019SerPro: 5.019 ± 1.231
2.868SerGln: 2.868 ± 1.602
4.063SerArg: 4.063 ± 1.571
8.365SerSer: 8.365 ± 1.546
5.019SerThr: 5.019 ± 0.812
6.692SerVal: 6.692 ± 2.954
1.434SerTrp: 1.434 ± 0.457
3.824SerTyr: 3.824 ± 0.76
0.0SerXaa: 0.0 ± 0.0
Thr
4.78ThrAla: 4.78 ± 0.668
0.956ThrCys: 0.956 ± 0.52
4.302ThrAsp: 4.302 ± 1.114
3.346ThrGlu: 3.346 ± 1.336
1.195ThrPhe: 1.195 ± 0.513
3.107ThrGly: 3.107 ± 1.112
1.195ThrHis: 1.195 ± 0.455
6.214ThrIle: 6.214 ± 1.402
3.824ThrLys: 3.824 ± 1.006
4.063ThrLeu: 4.063 ± 1.309
3.585ThrMet: 3.585 ± 0.716
2.151ThrAsn: 2.151 ± 0.525
2.151ThrPro: 2.151 ± 0.831
1.673ThrGln: 1.673 ± 1.009
1.673ThrArg: 1.673 ± 0.601
5.019ThrSer: 5.019 ± 0.769
5.019ThrThr: 5.019 ± 2.113
2.39ThrVal: 2.39 ± 0.793
0.717ThrTrp: 0.717 ± 0.319
1.912ThrTyr: 1.912 ± 0.639
0.0ThrXaa: 0.0 ± 0.0
Val
2.629ValAla: 2.629 ± 0.886
1.673ValCys: 1.673 ± 0.474
2.868ValAsp: 2.868 ± 0.708
3.824ValGlu: 3.824 ± 0.447
1.673ValPhe: 1.673 ± 0.571
1.195ValGly: 1.195 ± 0.525
2.39ValHis: 2.39 ± 0.908
3.107ValIle: 3.107 ± 1.526
4.78ValLys: 4.78 ± 1.566
4.78ValLeu: 4.78 ± 0.73
1.434ValMet: 1.434 ± 0.762
2.629ValAsn: 2.629 ± 1.171
4.302ValPro: 4.302 ± 0.765
0.717ValGln: 0.717 ± 0.32
3.585ValArg: 3.585 ± 0.834
5.019ValSer: 5.019 ± 1.649
5.019ValThr: 5.019 ± 1.099
2.151ValVal: 2.151 ± 1.223
0.478ValTrp: 0.478 ± 0.555
0.956ValTyr: 0.956 ± 0.52
0.0ValXaa: 0.0 ± 0.0
Trp
0.478TrpAla: 0.478 ± 0.397
0.0TrpCys: 0.0 ± 0.0
0.956TrpAsp: 0.956 ± 0.608
1.195TrpGlu: 1.195 ± 0.388
0.478TrpPhe: 0.478 ± 0.274
0.956TrpGly: 0.956 ± 0.432
0.478TrpHis: 0.478 ± 0.421
0.478TrpIle: 0.478 ± 0.31
0.956TrpLys: 0.956 ± 0.3
1.673TrpLeu: 1.673 ± 0.727
0.478TrpMet: 0.478 ± 0.261
1.195TrpAsn: 1.195 ± 0.558
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.195TrpArg: 1.195 ± 0.358
1.434TrpSer: 1.434 ± 0.475
0.239TrpThr: 0.239 ± 0.155
0.717TrpVal: 0.717 ± 0.641
0.0TrpTrp: 0.0 ± 0.0
0.478TrpTyr: 0.478 ± 0.31
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.195TyrAla: 1.195 ± 0.557
1.673TyrCys: 1.673 ± 0.502
1.912TyrAsp: 1.912 ± 0.456
1.673TyrGlu: 1.673 ± 0.647
1.673TyrPhe: 1.673 ± 0.796
0.717TyrGly: 0.717 ± 0.385
1.912TyrHis: 1.912 ± 0.787
3.346TyrIle: 3.346 ± 0.467
2.868TyrLys: 2.868 ± 0.85
5.258TyrLeu: 5.258 ± 0.796
0.956TyrMet: 0.956 ± 0.729
2.629TyrAsn: 2.629 ± 0.522
1.434TyrPro: 1.434 ± 0.295
0.956TyrGln: 0.956 ± 0.62
0.717TyrArg: 0.717 ± 0.511
4.78TyrSer: 4.78 ± 1.51
2.151TyrThr: 2.151 ± 0.857
2.868TyrVal: 2.868 ± 0.452
0.478TyrTrp: 0.478 ± 0.256
1.195TyrTyr: 1.195 ± 0.44
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4185 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski