Amino acid dipepetide frequency for Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.409AlaAla: 3.409 ± 0.32
1.512AlaCys: 1.512 ± 0.228
1.808AlaAsp: 1.808 ± 0.229
3.261AlaGlu: 3.261 ± 1.111
2.194AlaPhe: 2.194 ± 0.195
1.749AlaGly: 1.749 ± 0.291
1.186AlaHis: 1.186 ± 0.22
3.883AlaIle: 3.883 ± 0.428
3.201AlaLys: 3.201 ± 0.291
5.395AlaLeu: 5.395 ± 0.421
1.482AlaMet: 1.482 ± 0.209
2.46AlaAsn: 2.46 ± 0.196
2.786AlaPro: 2.786 ± 0.325
2.134AlaGln: 2.134 ± 0.268
1.393AlaArg: 1.393 ± 0.181
4.506AlaSer: 4.506 ± 0.295
3.29AlaThr: 3.29 ± 0.317
3.616AlaVal: 3.616 ± 0.378
0.652AlaTrp: 0.652 ± 0.134
1.749AlaTyr: 1.749 ± 0.226
0.0AlaXaa: 0.0 ± 0.0
Cys
1.097CysAla: 1.097 ± 0.202
0.771CysCys: 0.771 ± 0.167
1.186CysAsp: 1.186 ± 0.197
1.275CysGlu: 1.275 ± 0.181
1.215CysPhe: 1.215 ± 0.165
1.215CysGly: 1.215 ± 0.275
0.622CysHis: 0.622 ± 0.105
1.838CysIle: 1.838 ± 0.245
1.749CysLys: 1.749 ± 0.258
3.409CysLeu: 3.409 ± 0.447
0.622CysMet: 0.622 ± 0.14
1.571CysAsn: 1.571 ± 0.261
1.452CysPro: 1.452 ± 0.201
1.215CysGln: 1.215 ± 0.216
0.682CysArg: 0.682 ± 0.138
2.075CysSer: 2.075 ± 0.289
1.779CysThr: 1.779 ± 0.279
2.075CysVal: 2.075 ± 0.277
0.326CysTrp: 0.326 ± 0.106
1.215CysTyr: 1.215 ± 0.178
0.0CysXaa: 0.0 ± 0.0
Asp
2.282AspAla: 2.282 ± 0.298
1.097AspCys: 1.097 ± 0.154
2.371AspAsp: 2.371 ± 0.356
4.743AspGlu: 4.743 ± 2.308
2.342AspPhe: 2.342 ± 0.251
1.541AspGly: 1.541 ± 0.256
0.622AspHis: 0.622 ± 0.147
4.002AspIle: 4.002 ± 0.376
2.52AspLys: 2.52 ± 0.264
5.009AspLeu: 5.009 ± 0.299
1.156AspMet: 1.156 ± 0.187
2.045AspAsn: 2.045 ± 0.319
2.52AspPro: 2.52 ± 0.275
1.334AspGln: 1.334 ± 0.185
1.512AspArg: 1.512 ± 0.209
3.616AspSer: 3.616 ± 0.51
3.35AspThr: 3.35 ± 0.307
2.727AspVal: 2.727 ± 0.291
0.563AspTrp: 0.563 ± 0.144
1.808AspTyr: 1.808 ± 0.213
0.0AspXaa: 0.0 ± 0.0
Glu
4.298GluAla: 4.298 ± 1.117
1.156GluCys: 1.156 ± 0.214
4.387GluAsp: 4.387 ± 1.099
6.284GluGlu: 6.284 ± 2.199
2.134GluPhe: 2.134 ± 0.323
4.002GluGly: 4.002 ± 2.107
1.66GluHis: 1.66 ± 0.176
3.942GluIle: 3.942 ± 0.377
3.794GluLys: 3.794 ± 0.293
4.476GluLeu: 4.476 ± 0.448
1.275GluMet: 1.275 ± 0.198
3.616GluAsn: 3.616 ± 0.278
1.749GluPro: 1.749 ± 0.202
1.541GluGln: 1.541 ± 0.183
1.245GluArg: 1.245 ± 0.184
3.616GluSer: 3.616 ± 0.297
4.002GluThr: 4.002 ± 0.303
2.846GluVal: 2.846 ± 0.219
0.385GluTrp: 0.385 ± 0.102
1.571GluTyr: 1.571 ± 0.258
0.0GluXaa: 0.0 ± 0.0
Phe
1.66PheAla: 1.66 ± 0.254
1.482PheCys: 1.482 ± 0.237
2.134PheAsp: 2.134 ± 0.256
2.105PheGlu: 2.105 ± 0.283
2.312PhePhe: 2.312 ± 0.269
1.867PheGly: 1.867 ± 0.288
1.037PheHis: 1.037 ± 0.185
4.18PheIle: 4.18 ± 0.405
3.972PheLys: 3.972 ± 0.355
5.751PheLeu: 5.751 ± 0.441
1.186PheMet: 1.186 ± 0.218
2.223PheAsn: 2.223 ± 0.261
2.253PhePro: 2.253 ± 0.327
1.867PheGln: 1.867 ± 0.212
1.63PheArg: 1.63 ± 0.193
4.268PheSer: 4.268 ± 0.33
2.49PheThr: 2.49 ± 0.288
2.816PheVal: 2.816 ± 0.344
0.534PheTrp: 0.534 ± 0.114
2.52PheTyr: 2.52 ± 0.276
0.0PheXaa: 0.0 ± 0.0
Gly
2.431GlyAla: 2.431 ± 0.301
0.919GlyCys: 0.919 ± 0.222
2.757GlyAsp: 2.757 ± 1.056
3.083GlyGlu: 3.083 ± 0.943
1.927GlyPhe: 1.927 ± 0.263
1.571GlyGly: 1.571 ± 0.225
1.008GlyHis: 1.008 ± 0.166
2.401GlyIle: 2.401 ± 0.223
2.194GlyLys: 2.194 ± 0.27
3.557GlyLeu: 3.557 ± 0.412
0.86GlyMet: 0.86 ± 0.19
2.075GlyAsn: 2.075 ± 0.276
1.986GlyPro: 1.986 ± 0.263
1.541GlyGln: 1.541 ± 0.201
1.66GlyArg: 1.66 ± 0.245
2.875GlySer: 2.875 ± 0.358
2.727GlyThr: 2.727 ± 0.308
2.52GlyVal: 2.52 ± 0.338
0.237GlyTrp: 0.237 ± 0.089
1.245GlyTyr: 1.245 ± 0.212
0.0GlyXaa: 0.0 ± 0.0
His
0.978HisAla: 0.978 ± 0.166
0.711HisCys: 0.711 ± 0.149
0.86HisAsp: 0.86 ± 0.134
1.215HisGlu: 1.215 ± 0.153
1.482HisPhe: 1.482 ± 0.209
1.215HisGly: 1.215 ± 0.143
0.652HisHis: 0.652 ± 0.139
2.875HisIle: 2.875 ± 0.296
1.956HisLys: 1.956 ± 0.171
3.083HisLeu: 3.083 ± 0.264
0.593HisMet: 0.593 ± 0.123
1.156HisAsn: 1.156 ± 0.204
1.423HisPro: 1.423 ± 0.242
1.037HisGln: 1.037 ± 0.177
0.86HisArg: 0.86 ± 0.19
1.66HisSer: 1.66 ± 0.245
2.075HisThr: 2.075 ± 0.222
2.342HisVal: 2.342 ± 0.281
0.178HisTrp: 0.178 ± 0.089
0.741HisTyr: 0.741 ± 0.188
0.0HisXaa: 0.0 ± 0.0
Ile
3.35IleAla: 3.35 ± 0.232
2.075IleCys: 2.075 ± 0.291
3.468IleAsp: 3.468 ± 0.442
3.765IleGlu: 3.765 ± 0.389
3.438IlePhe: 3.438 ± 0.355
2.727IleGly: 2.727 ± 0.318
1.986IleHis: 1.986 ± 0.163
5.039IleIle: 5.039 ± 0.442
4.802IleLys: 4.802 ± 0.438
7.677IleLeu: 7.677 ± 0.498
1.69IleMet: 1.69 ± 0.218
4.298IleAsn: 4.298 ± 0.361
3.409IlePro: 3.409 ± 0.401
2.697IleGln: 2.697 ± 0.425
2.016IleArg: 2.016 ± 0.241
6.136IleSer: 6.136 ± 0.498
4.535IleThr: 4.535 ± 0.339
3.942IleVal: 3.942 ± 0.364
0.652IleTrp: 0.652 ± 0.126
3.083IleTyr: 3.083 ± 0.358
0.0IleXaa: 0.0 ± 0.0
Lys
3.261LysAla: 3.261 ± 0.386
1.927LysCys: 1.927 ± 0.301
3.35LysAsp: 3.35 ± 0.357
3.053LysGlu: 3.053 ± 0.296
2.964LysPhe: 2.964 ± 0.329
1.808LysGly: 1.808 ± 0.221
2.194LysHis: 2.194 ± 0.277
4.802LysIle: 4.802 ± 0.479
5.276LysLys: 5.276 ± 0.452
6.995LysLeu: 6.995 ± 0.494
1.571LysMet: 1.571 ± 0.274
4.357LysAsn: 4.357 ± 0.308
3.409LysPro: 3.409 ± 0.376
2.668LysGln: 2.668 ± 0.368
2.638LysArg: 2.638 ± 0.308
5.187LysSer: 5.187 ± 0.426
5.365LysThr: 5.365 ± 0.496
3.201LysVal: 3.201 ± 0.31
0.534LysTrp: 0.534 ± 0.125
2.401LysTyr: 2.401 ± 0.261
0.0LysXaa: 0.0 ± 0.0
Leu
5.721LeuAla: 5.721 ± 0.401
2.964LeuCys: 2.964 ± 0.397
4.446LeuAsp: 4.446 ± 0.323
5.839LeuGlu: 5.839 ± 0.411
5.128LeuPhe: 5.128 ± 0.49
3.735LeuGly: 3.735 ± 0.326
2.875LeuHis: 2.875 ± 0.272
5.751LeuIle: 5.751 ± 0.387
7.44LeuLys: 7.44 ± 0.593
10.819LeuLeu: 10.819 ± 0.607
2.223LeuMet: 2.223 ± 0.319
6.106LeuAsn: 6.106 ± 0.462
5.602LeuPro: 5.602 ± 0.332
4.832LeuGln: 4.832 ± 0.493
3.172LeuArg: 3.172 ± 0.318
9.367LeuSer: 9.367 ± 0.653
6.729LeuThr: 6.729 ± 0.398
5.098LeuVal: 5.098 ± 0.398
1.186LeuTrp: 1.186 ± 0.194
3.765LeuTyr: 3.765 ± 0.332
0.0LeuXaa: 0.0 ± 0.0
Met
1.452MetAla: 1.452 ± 0.249
0.711MetCys: 0.711 ± 0.209
0.889MetAsp: 0.889 ± 0.16
1.067MetGlu: 1.067 ± 0.169
1.779MetPhe: 1.779 ± 0.246
0.741MetGly: 0.741 ± 0.189
0.563MetHis: 0.563 ± 0.124
0.889MetIle: 0.889 ± 0.176
0.919MetLys: 0.919 ± 0.138
3.053MetLeu: 3.053 ± 0.38
0.474MetMet: 0.474 ± 0.166
1.008MetAsn: 1.008 ± 0.168
1.008MetPro: 1.008 ± 0.191
1.126MetGln: 1.126 ± 0.183
0.563MetArg: 0.563 ± 0.152
2.016MetSer: 2.016 ± 0.227
1.69MetThr: 1.69 ± 0.285
1.037MetVal: 1.037 ± 0.211
0.267MetTrp: 0.267 ± 0.093
0.889MetTyr: 0.889 ± 0.178
0.0MetXaa: 0.0 ± 0.0
Asn
2.312AsnAla: 2.312 ± 0.196
1.364AsnCys: 1.364 ± 0.209
1.986AsnAsp: 1.986 ± 0.236
2.105AsnGlu: 2.105 ± 0.209
2.549AsnPhe: 2.549 ± 0.275
2.371AsnGly: 2.371 ± 0.356
1.156AsnHis: 1.156 ± 0.185
5.632AsnIle: 5.632 ± 0.466
3.883AsnLys: 3.883 ± 0.389
5.988AsnLeu: 5.988 ± 0.342
1.393AsnMet: 1.393 ± 0.201
3.557AsnAsn: 3.557 ± 0.391
2.105AsnPro: 2.105 ± 0.197
1.541AsnGln: 1.541 ± 0.306
1.452AsnArg: 1.452 ± 0.192
4.743AsnSer: 4.743 ± 0.379
3.735AsnThr: 3.735 ± 0.554
4.091AsnVal: 4.091 ± 0.32
0.741AsnTrp: 0.741 ± 0.133
2.194AsnTyr: 2.194 ± 0.244
0.0AsnXaa: 0.0 ± 0.0
Pro
2.105ProAla: 2.105 ± 0.239
1.571ProCys: 1.571 ± 0.242
1.838ProAsp: 1.838 ± 0.232
2.164ProGlu: 2.164 ± 0.265
2.016ProPhe: 2.016 ± 0.239
2.016ProGly: 2.016 ± 0.262
1.66ProHis: 1.66 ± 0.205
3.498ProIle: 3.498 ± 0.32
4.002ProLys: 4.002 ± 0.528
4.654ProLeu: 4.654 ± 0.384
0.978ProMet: 0.978 ± 0.197
2.401ProAsn: 2.401 ± 0.284
2.697ProPro: 2.697 ± 0.313
2.579ProGln: 2.579 ± 0.339
2.431ProArg: 2.431 ± 0.273
4.357ProSer: 4.357 ± 0.335
3.201ProThr: 3.201 ± 0.403
3.468ProVal: 3.468 ± 0.317
0.741ProTrp: 0.741 ± 0.188
2.164ProTyr: 2.164 ± 0.318
0.0ProXaa: 0.0 ± 0.0
Gln
2.223GlnAla: 2.223 ± 0.28
1.097GlnCys: 1.097 ± 0.185
2.282GlnAsp: 2.282 ± 0.315
2.016GlnGlu: 2.016 ± 0.286
1.749GlnPhe: 1.749 ± 0.257
1.63GlnGly: 1.63 ± 0.27
1.719GlnHis: 1.719 ± 0.264
2.846GlnIle: 2.846 ± 0.25
2.697GlnLys: 2.697 ± 0.514
3.527GlnLeu: 3.527 ± 0.312
0.622GlnMet: 0.622 ± 0.119
2.371GlnAsn: 2.371 ± 0.239
2.016GlnPro: 2.016 ± 0.316
1.63GlnGln: 1.63 ± 0.27
1.63GlnArg: 1.63 ± 0.258
2.786GlnSer: 2.786 ± 0.385
2.697GlnThr: 2.697 ± 0.266
1.423GlnVal: 1.423 ± 0.163
0.534GlnTrp: 0.534 ± 0.112
1.571GlnTyr: 1.571 ± 0.291
0.0GlnXaa: 0.0 ± 0.0
Arg
2.045ArgAla: 2.045 ± 0.329
0.8ArgCys: 0.8 ± 0.167
1.749ArgAsp: 1.749 ± 0.224
2.253ArgGlu: 2.253 ± 0.236
1.156ArgPhe: 1.156 ± 0.176
1.423ArgGly: 1.423 ± 0.23
1.008ArgHis: 1.008 ± 0.173
1.808ArgIle: 1.808 ± 0.21
2.134ArgLys: 2.134 ± 0.266
3.35ArgLeu: 3.35 ± 0.329
0.682ArgMet: 0.682 ± 0.164
1.719ArgAsn: 1.719 ± 0.236
1.897ArgPro: 1.897 ± 0.213
1.215ArgGln: 1.215 ± 0.187
1.808ArgArg: 1.808 ± 0.316
2.075ArgSer: 2.075 ± 0.286
1.956ArgThr: 1.956 ± 0.248
1.956ArgVal: 1.956 ± 0.226
0.267ArgTrp: 0.267 ± 0.099
1.156ArgTyr: 1.156 ± 0.206
0.0ArgXaa: 0.0 ± 0.0
Ser
4.12SerAla: 4.12 ± 0.373
2.223SerCys: 2.223 ± 0.265
3.913SerAsp: 3.913 ± 0.434
4.328SerGlu: 4.328 ± 0.379
4.031SerPhe: 4.031 ± 0.4
3.172SerGly: 3.172 ± 0.413
2.282SerHis: 2.282 ± 0.23
5.899SerIle: 5.899 ± 0.426
5.069SerLys: 5.069 ± 0.359
8.3SerLeu: 8.3 ± 0.539
1.601SerMet: 1.601 ± 0.213
4.624SerAsn: 4.624 ± 0.386
4.031SerPro: 4.031 ± 0.362
3.735SerGln: 3.735 ± 0.305
2.994SerArg: 2.994 ± 0.247
7.351SerSer: 7.351 ± 0.654
6.729SerThr: 6.729 ± 0.492
5.632SerVal: 5.632 ± 0.404
0.86SerTrp: 0.86 ± 0.17
2.401SerTyr: 2.401 ± 0.256
0.0SerXaa: 0.0 ± 0.0
Thr
3.261ThrAla: 3.261 ± 0.368
1.986ThrCys: 1.986 ± 0.263
3.409ThrAsp: 3.409 ± 0.377
4.002ThrGlu: 4.002 ± 0.326
3.379ThrPhe: 3.379 ± 0.338
2.52ThrGly: 2.52 ± 0.34
1.927ThrHis: 1.927 ± 0.298
4.268ThrIle: 4.268 ± 0.417
4.002ThrLys: 4.002 ± 0.383
6.551ThrLeu: 6.551 ± 0.536
1.304ThrMet: 1.304 ± 0.156
2.875ThrAsn: 2.875 ± 0.319
3.616ThrPro: 3.616 ± 0.352
2.49ThrGln: 2.49 ± 0.273
1.719ThrArg: 1.719 ± 0.262
7.144ThrSer: 7.144 ± 0.512
4.802ThrThr: 4.802 ± 0.431
5.069ThrVal: 5.069 ± 0.468
0.771ThrTrp: 0.771 ± 0.185
3.261ThrTyr: 3.261 ± 0.396
0.0ThrXaa: 0.0 ± 0.0
Val
3.053ValAla: 3.053 ± 0.368
1.69ValCys: 1.69 ± 0.219
2.282ValAsp: 2.282 ± 0.3
3.172ValGlu: 3.172 ± 0.329
4.002ValPhe: 4.002 ± 0.377
2.164ValGly: 2.164 ± 0.287
1.838ValHis: 1.838 ± 0.264
3.705ValIle: 3.705 ± 0.308
3.942ValLys: 3.942 ± 0.365
6.64ValLeu: 6.64 ± 0.508
1.156ValMet: 1.156 ± 0.165
3.231ValAsn: 3.231 ± 0.344
4.15ValPro: 4.15 ± 0.322
2.371ValGln: 2.371 ± 0.255
1.512ValArg: 1.512 ± 0.24
5.632ValSer: 5.632 ± 0.509
3.587ValThr: 3.587 ± 0.358
3.35ValVal: 3.35 ± 0.384
0.622ValTrp: 0.622 ± 0.167
2.608ValTyr: 2.608 ± 0.312
0.0ValXaa: 0.0 ± 0.0
Trp
0.771TrpAla: 0.771 ± 0.171
0.326TrpCys: 0.326 ± 0.12
0.474TrpAsp: 0.474 ± 0.14
0.474TrpGlu: 0.474 ± 0.116
0.415TrpPhe: 0.415 ± 0.115
0.415TrpGly: 0.415 ± 0.113
0.326TrpHis: 0.326 ± 0.095
0.652TrpIle: 0.652 ± 0.139
0.652TrpLys: 0.652 ± 0.136
0.889TrpLeu: 0.889 ± 0.145
0.178TrpMet: 0.178 ± 0.074
0.593TrpAsn: 0.593 ± 0.107
0.563TrpPro: 0.563 ± 0.112
0.534TrpGln: 0.534 ± 0.123
0.296TrpArg: 0.296 ± 0.109
0.771TrpSer: 0.771 ± 0.161
1.008TrpThr: 1.008 ± 0.212
0.622TrpVal: 0.622 ± 0.131
0.0TrpTrp: 0.0 ± 0.0
0.563TrpTyr: 0.563 ± 0.12
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.838TyrAla: 1.838 ± 0.259
1.008TyrCys: 1.008 ± 0.176
1.571TyrAsp: 1.571 ± 0.203
1.779TyrGlu: 1.779 ± 0.192
2.075TyrPhe: 2.075 ± 0.288
1.69TyrGly: 1.69 ± 0.23
0.771TyrHis: 0.771 ± 0.141
2.875TyrIle: 2.875 ± 0.303
2.757TyrLys: 2.757 ± 0.253
3.676TyrLeu: 3.676 ± 0.389
1.067TyrMet: 1.067 ± 0.212
2.608TyrAsn: 2.608 ± 0.263
1.867TyrPro: 1.867 ± 0.222
0.978TyrGln: 0.978 ± 0.15
1.245TyrArg: 1.245 ± 0.2
3.142TyrSer: 3.142 ± 0.383
2.608TyrThr: 2.608 ± 0.35
2.875TyrVal: 2.875 ± 0.324
0.474TyrTrp: 0.474 ± 0.115
1.423TyrTyr: 1.423 ± 0.215
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 77 proteins (33737 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski