Amino acid dipepetide frequency for Fusarium culmorum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.268AlaAla: 8.268 ± 0.066	1.107AlaCys: 1.107 ± 0.014	4.152AlaAsp: 4.152 ± 0.027	4.921AlaGlu: 4.921 ± 0.037	3.098AlaPhe: 3.098 ± 0.025	5.465AlaGly: 5.465 ± 0.039	1.662AlaHis: 1.662 ± 0.019	4.428AlaIle: 4.428 ± 0.031	4.229AlaLys: 4.229 ± 0.037	7.312AlaLeu: 7.312 ± 0.042	2.004AlaMet: 2.004 ± 0.018	2.954AlaAsn: 2.954 ± 0.026	4.62AlaPro: 4.62 ± 0.043	3.336AlaGln: 3.336 ± 0.029	4.465AlaArg: 4.465 ± 0.033	6.979AlaSer: 6.979 ± 0.04	5.248AlaThr: 5.248 ± 0.035	5.173AlaVal: 5.173 ± 0.035	1.157AlaTrp: 1.157 ± 0.015	2.11AlaTyr: 2.11 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.94CysAla: 0.94 ± 0.014	0.276CysCys: 0.276 ± 0.009	0.722CysAsp: 0.722 ± 0.013	0.641CysGlu: 0.641 ± 0.012	0.593CysPhe: 0.593 ± 0.011	0.969CysGly: 0.969 ± 0.016	0.352CysHis: 0.352 ± 0.008	0.775CysIle: 0.775 ± 0.012	0.593CysLys: 0.593 ± 0.011	1.302CysLeu: 1.302 ± 0.02	0.292CysMet: 0.292 ± 0.008	0.487CysAsn: 0.487 ± 0.011	0.684CysPro: 0.684 ± 0.014	0.495CysGln: 0.495 ± 0.011	0.764CysArg: 0.764 ± 0.013	0.933CysSer: 0.933 ± 0.014	0.752CysThr: 0.752 ± 0.014	0.819CysVal: 0.819 ± 0.014	0.225CysTrp: 0.225 ± 0.007	0.387CysTyr: 0.387 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.69AspAla: 4.69 ± 0.028	0.685AspCys: 0.685 ± 0.013	4.672AspAsp: 4.672 ± 0.042	4.688AspGlu: 4.688 ± 0.037	2.3AspPhe: 2.3 ± 0.02	4.127AspGly: 4.127 ± 0.033	1.276AspHis: 1.276 ± 0.015	3.29AspIle: 3.29 ± 0.029	2.827AspLys: 2.827 ± 0.024	5.098AspLeu: 5.098 ± 0.03	1.419AspMet: 1.419 ± 0.017	2.196AspAsn: 2.196 ± 0.019	3.289AspPro: 3.289 ± 0.03	1.991AspGln: 1.991 ± 0.02	2.999AspArg: 2.999 ± 0.03	4.273AspSer: 4.273 ± 0.03	3.184AspThr: 3.184 ± 0.025	3.758AspVal: 3.758 ± 0.027	0.952AspTrp: 0.952 ± 0.014	1.642AspTyr: 1.642 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.408GluAla: 5.408 ± 0.047	0.675GluCys: 0.675 ± 0.012	4.275GluAsp: 4.275 ± 0.035	5.296GluGlu: 5.296 ± 0.05	2.005GluPhe: 2.005 ± 0.019	3.623GluGly: 3.623 ± 0.031	1.411GluHis: 1.411 ± 0.017	3.1GluIle: 3.1 ± 0.025	3.775GluLys: 3.775 ± 0.032	5.109GluLeu: 5.109 ± 0.035	1.5GluMet: 1.5 ± 0.015	2.384GluAsn: 2.384 ± 0.022	2.961GluPro: 2.961 ± 0.036	2.505GluGln: 2.505 ± 0.022	3.695GluArg: 3.695 ± 0.031	4.368GluSer: 4.368 ± 0.034	3.841GluThr: 3.841 ± 0.037	3.539GluVal: 3.539 ± 0.025	0.921GluTrp: 0.921 ± 0.013	1.679GluTyr: 1.679 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	2.987PheAla: 2.987 ± 0.024	0.591PheCys: 0.591 ± 0.011	2.375PheAsp: 2.375 ± 0.019	2.196PheGlu: 2.196 ± 0.023	1.668PhePhe: 1.668 ± 0.021	2.87PheGly: 2.87 ± 0.024	0.907PheHis: 0.907 ± 0.013	1.953PheIle: 1.953 ± 0.022	1.651PheLys: 1.651 ± 0.018	3.408PheLeu: 3.408 ± 0.031	0.857PheMet: 0.857 ± 0.013	1.552PheAsn: 1.552 ± 0.017	1.886PhePro: 1.886 ± 0.02	1.428PheGln: 1.428 ± 0.015	1.876PheArg: 1.876 ± 0.017	3.002PheSer: 3.002 ± 0.023	2.228PheThr: 2.228 ± 0.023	2.437PheVal: 2.437 ± 0.023	0.675PheTrp: 0.675 ± 0.012	1.14PheTyr: 1.14 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.992GlyAla: 4.992 ± 0.04	0.915GlyCys: 0.915 ± 0.015	3.746GlyAsp: 3.746 ± 0.031	3.501GlyGlu: 3.501 ± 0.029	2.841GlyPhe: 2.841 ± 0.027	5.325GlyGly: 5.325 ± 0.052	1.685GlyHis: 1.685 ± 0.018	3.633GlyIle: 3.633 ± 0.029	3.487GlyLys: 3.487 ± 0.029	5.962GlyLeu: 5.962 ± 0.032	1.599GlyMet: 1.599 ± 0.019	2.702GlyAsn: 2.702 ± 0.026	3.259GlyPro: 3.259 ± 0.028	2.586GlyGln: 2.586 ± 0.023	3.902GlyArg: 3.902 ± 0.035	5.643GlySer: 5.643 ± 0.041	4.021GlyThr: 4.021 ± 0.045	4.236GlyVal: 4.236 ± 0.028	1.17GlyTrp: 1.17 ± 0.014	2.153GlyTyr: 2.153 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.708HisAla: 1.708 ± 0.017	0.337HisCys: 0.337 ± 0.008	1.437HisAsp: 1.437 ± 0.016	1.355HisGlu: 1.355 ± 0.017	0.901HisPhe: 0.901 ± 0.012	1.697HisGly: 1.697 ± 0.019	0.832HisHis: 0.832 ± 0.015	1.247HisIle: 1.247 ± 0.014	0.999HisLys: 0.999 ± 0.015	2.18HisLeu: 2.18 ± 0.024	0.531HisMet: 0.531 ± 0.009	0.897HisAsn: 0.897 ± 0.013	1.524HisPro: 1.524 ± 0.018	1.034HisGln: 1.034 ± 0.017	1.459HisArg: 1.459 ± 0.016	1.754HisSer: 1.754 ± 0.022	1.221HisThr: 1.221 ± 0.016	1.441HisVal: 1.441 ± 0.018	0.349HisTrp: 0.349 ± 0.009	0.715HisTyr: 0.715 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.292IleAla: 4.292 ± 0.027	0.791IleCys: 0.791 ± 0.013	3.044IleAsp: 3.044 ± 0.024	3.064IleGlu: 3.064 ± 0.024	2.069IlePhe: 2.069 ± 0.02	3.305IleGly: 3.305 ± 0.026	1.197IleHis: 1.197 ± 0.016	2.728IleIle: 2.728 ± 0.025	2.453IleLys: 2.453 ± 0.021	4.583IleLeu: 4.583 ± 0.031	1.124IleMet: 1.124 ± 0.015	1.987IleAsn: 1.987 ± 0.019	3.052IlePro: 3.052 ± 0.024	1.974IleGln: 1.974 ± 0.02	2.767IleArg: 2.767 ± 0.025	3.943IleSer: 3.943 ± 0.024	3.051IleThr: 3.051 ± 0.032	3.35IleVal: 3.35 ± 0.025	0.801IleTrp: 0.801 ± 0.012	1.447IleTyr: 1.447 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.385LysAla: 4.385 ± 0.035	0.578LysCys: 0.578 ± 0.012	3.19LysAsp: 3.19 ± 0.028	3.503LysGlu: 3.503 ± 0.032	1.561LysPhe: 1.561 ± 0.019	3.126LysGly: 3.126 ± 0.027	1.217LysHis: 1.217 ± 0.015	2.394LysIle: 2.394 ± 0.024	3.649LysLys: 3.649 ± 0.041	4.208LysLeu: 4.208 ± 0.029	1.117LysMet: 1.117 ± 0.015	1.989LysAsn: 1.989 ± 0.022	2.977LysPro: 2.977 ± 0.029	1.942LysGln: 1.942 ± 0.022	3.337LysArg: 3.337 ± 0.027	3.689LysSer: 3.689 ± 0.03	3.206LysThr: 3.206 ± 0.025	2.991LysVal: 2.991 ± 0.026	0.734LysTrp: 0.734 ± 0.012	1.449LysTyr: 1.449 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.438LeuAla: 7.438 ± 0.042	1.249LeuCys: 1.249 ± 0.016	5.163LeuAsp: 5.163 ± 0.037	5.415LeuGlu: 5.415 ± 0.043	3.306LeuPhe: 3.306 ± 0.029	5.779LeuGly: 5.779 ± 0.037	2.092LeuHis: 2.092 ± 0.025	4.08LeuIle: 4.08 ± 0.032	4.302LeuLys: 4.302 ± 0.033	7.881LeuLeu: 7.881 ± 0.052	1.866LeuMet: 1.866 ± 0.018	3.206LeuAsn: 3.206 ± 0.025	5.197LeuPro: 5.197 ± 0.034	3.624LeuGln: 3.624 ± 0.03	5.338LeuArg: 5.338 ± 0.037	7.092LeuSer: 7.092 ± 0.045	4.782LeuThr: 4.782 ± 0.029	5.432LeuVal: 5.432 ± 0.036	1.22LeuTrp: 1.22 ± 0.016	2.324LeuTyr: 2.324 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.312MetAla: 2.312 ± 0.02	0.268MetCys: 0.268 ± 0.007	1.338MetAsp: 1.338 ± 0.015	1.31MetGlu: 1.31 ± 0.015	0.799MetPhe: 0.799 ± 0.013	1.545MetGly: 1.545 ± 0.017	0.493MetHis: 0.493 ± 0.009	1.093MetIle: 1.093 ± 0.013	1.087MetLys: 1.087 ± 0.014	1.857MetLeu: 1.857 ± 0.017	0.649MetMet: 0.649 ± 0.009	0.866MetAsn: 0.866 ± 0.012	1.342MetPro: 1.342 ± 0.017	0.845MetGln: 0.845 ± 0.013	1.265MetArg: 1.265 ± 0.017	2.073MetSer: 2.073 ± 0.021	1.438MetThr: 1.438 ± 0.015	1.359MetVal: 1.359 ± 0.018	0.286MetTrp: 0.286 ± 0.006	0.558MetTyr: 0.558 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.124AsnAla: 3.124 ± 0.022	0.489AsnCys: 0.489 ± 0.01	2.232AsnAsp: 2.232 ± 0.022	2.142AsnGlu: 2.142 ± 0.019	1.425AsnPhe: 1.425 ± 0.014	3.076AsnGly: 3.076 ± 0.024	0.9AsnHis: 0.9 ± 0.013	2.161AsnIle: 2.161 ± 0.02	1.891AsnLys: 1.891 ± 0.018	3.34AsnLeu: 3.34 ± 0.024	0.958AsnMet: 0.958 ± 0.012	1.723AsnAsn: 1.723 ± 0.021	2.442AsnPro: 2.442 ± 0.023	1.423AsnGln: 1.423 ± 0.018	1.976AsnArg: 1.976 ± 0.023	2.897AsnSer: 2.897 ± 0.026	2.334AsnThr: 2.334 ± 0.022	2.38AsnVal: 2.38 ± 0.02	0.598AsnTrp: 0.598 ± 0.01	1.112AsnTyr: 1.112 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.84ProAla: 4.84 ± 0.045	0.557ProCys: 0.557 ± 0.012	3.279ProAsp: 3.279 ± 0.028	3.938ProGlu: 3.938 ± 0.029	2.036ProPhe: 2.036 ± 0.019	3.849ProGly: 3.849 ± 0.046	1.248ProHis: 1.248 ± 0.018	2.573ProIle: 2.573 ± 0.022	2.865ProLys: 2.865 ± 0.03	4.453ProLeu: 4.453 ± 0.032	1.155ProMet: 1.155 ± 0.015	2.203ProAsn: 2.203 ± 0.02	4.437ProPro: 4.437 ± 0.049	2.477ProGln: 2.477 ± 0.028	3.205ProArg: 3.205 ± 0.029	5.607ProSer: 5.607 ± 0.042	3.96ProThr: 3.96 ± 0.037	3.616ProVal: 3.616 ± 0.033	0.769ProTrp: 0.769 ± 0.011	1.493ProTyr: 1.493 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.38GlnAla: 3.38 ± 0.03	0.458GlnCys: 0.458 ± 0.01	2.315GlnAsp: 2.315 ± 0.017	2.449GlnGlu: 2.449 ± 0.025	1.288GlnPhe: 1.288 ± 0.015	2.509GlnGly: 2.509 ± 0.022	1.073GlnHis: 1.073 ± 0.015	1.887GlnIle: 1.887 ± 0.017	2.004GlnLys: 2.004 ± 0.019	3.344GlnLeu: 3.344 ± 0.029	0.902GlnMet: 0.902 ± 0.014	1.631GlnAsn: 1.631 ± 0.02	2.54GlnPro: 2.54 ± 0.032	2.389GlnGln: 2.389 ± 0.042	2.522GlnArg: 2.522 ± 0.025	3.087GlnSer: 3.087 ± 0.028	2.343GlnThr: 2.343 ± 0.023	2.278GlnVal: 2.278 ± 0.019	0.599GlnTrp: 0.599 ± 0.01	1.148GlnTyr: 1.148 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.234ArgAla: 4.234 ± 0.023	0.721ArgCys: 0.721 ± 0.013	3.4ArgAsp: 3.4 ± 0.031	3.532ArgGlu: 3.532 ± 0.03	2.093ArgPhe: 2.093 ± 0.02	3.505ArgGly: 3.505 ± 0.032	1.527ArgHis: 1.527 ± 0.018	2.838ArgIle: 2.838 ± 0.025	3.284ArgLys: 3.284 ± 0.027	5.169ArgLeu: 5.169 ± 0.033	1.283ArgMet: 1.283 ± 0.015	2.27ArgAsn: 2.27 ± 0.02	3.358ArgPro: 3.358 ± 0.033	2.545ArgGln: 2.545 ± 0.023	4.704ArgArg: 4.704 ± 0.04	4.541ArgSer: 4.541 ± 0.038	3.112ArgThr: 3.112 ± 0.025	3.253ArgVal: 3.253 ± 0.026	0.916ArgTrp: 0.916 ± 0.013	1.645ArgTyr: 1.645 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.165SerAla: 6.165 ± 0.038	0.958SerCys: 0.958 ± 0.017	4.488SerAsp: 4.488 ± 0.028	4.272SerGlu: 4.272 ± 0.031	3.1SerPhe: 3.1 ± 0.026	5.421SerGly: 5.421 ± 0.04	1.942SerHis: 1.942 ± 0.02	4.177SerIle: 4.177 ± 0.026	3.973SerLys: 3.973 ± 0.031	6.973SerLeu: 6.973 ± 0.041	1.812SerMet: 1.812 ± 0.018	3.14SerAsn: 3.14 ± 0.024	5.128SerPro: 5.128 ± 0.046	3.302SerGln: 3.302 ± 0.028	4.781SerArg: 4.781 ± 0.041	8.181SerSer: 8.181 ± 0.064	5.521SerThr: 5.521 ± 0.052	4.616SerVal: 4.616 ± 0.031	1.192SerTrp: 1.192 ± 0.015	2.149SerTyr: 2.149 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.107ThrAla: 5.107 ± 0.036	0.817ThrCys: 0.817 ± 0.014	3.052ThrAsp: 3.052 ± 0.024	3.423ThrGlu: 3.423 ± 0.034	2.294ThrPhe: 2.294 ± 0.021	4.173ThrGly: 4.173 ± 0.041	1.253ThrHis: 1.253 ± 0.017	3.347ThrIle: 3.347 ± 0.035	2.983ThrLys: 2.983 ± 0.024	5.174ThrLeu: 5.174 ± 0.035	1.288ThrMet: 1.288 ± 0.016	2.265ThrAsn: 2.265 ± 0.021	4.198ThrPro: 4.198 ± 0.035	2.182ThrGln: 2.182 ± 0.024	3.138ThrArg: 3.138 ± 0.028	5.379ThrSer: 5.379 ± 0.042	4.667ThrThr: 4.667 ± 0.073	3.921ThrVal: 3.921 ± 0.046	0.93ThrTrp: 0.93 ± 0.015	1.649ThrTyr: 1.649 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.176ValAla: 5.176 ± 0.03	0.862ValCys: 0.862 ± 0.013	3.831ValAsp: 3.831 ± 0.028	3.927ValGlu: 3.927 ± 0.029	2.52ValPhe: 2.52 ± 0.022	3.934ValGly: 3.934 ± 0.03	1.386ValHis: 1.386 ± 0.015	3.099ValIle: 3.099 ± 0.028	3.082ValLys: 3.082 ± 0.027	5.465ValLeu: 5.465 ± 0.036	1.377ValMet: 1.377 ± 0.015	2.305ValAsn: 2.305 ± 0.021	3.554ValPro: 3.554 ± 0.03	2.34ValGln: 2.34 ± 0.021	3.232ValArg: 3.232 ± 0.022	4.708ValSer: 4.708 ± 0.035	3.727ValThr: 3.727 ± 0.041	4.354ValVal: 4.354 ± 0.035	0.872ValTrp: 0.872 ± 0.013	1.752ValTyr: 1.752 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.146TrpAla: 1.146 ± 0.017	0.217TrpCys: 0.217 ± 0.007	0.95TrpAsp: 0.95 ± 0.014	0.886TrpGlu: 0.886 ± 0.015	0.585TrpPhe: 0.585 ± 0.012	0.974TrpGly: 0.974 ± 0.014	0.376TrpHis: 0.376 ± 0.008	0.81TrpIle: 0.81 ± 0.012	0.871TrpLys: 0.871 ± 0.013	1.39TrpLeu: 1.39 ± 0.018	0.387TrpMet: 0.387 ± 0.007	0.674TrpAsn: 0.674 ± 0.012	0.639TrpPro: 0.639 ± 0.011	0.599TrpGln: 0.599 ± 0.01	0.907TrpArg: 0.907 ± 0.013	1.112TrpSer: 1.112 ± 0.016	0.955TrpThr: 0.955 ± 0.011	0.907TrpVal: 0.907 ± 0.014	0.296TrpTrp: 0.296 ± 0.008	0.455TrpTyr: 0.455 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.096TyrAla: 2.096 ± 0.021	0.449TyrCys: 0.449 ± 0.01	1.696TyrAsp: 1.696 ± 0.017	1.608TyrGlu: 1.608 ± 0.019	1.205TyrPhe: 1.205 ± 0.017	2.087TyrGly: 2.087 ± 0.025	0.79TyrHis: 0.79 ± 0.014	1.409TyrIle: 1.409 ± 0.016	1.239TyrLys: 1.239 ± 0.016	2.579TyrLeu: 2.579 ± 0.021	0.66TyrMet: 0.66 ± 0.011	1.192TyrAsn: 1.192 ± 0.013	1.473TyrPro: 1.473 ± 0.019	1.13TyrGln: 1.13 ± 0.014	1.598TyrArg: 1.598 ± 0.018	2.029TyrSer: 2.029 ± 0.021	1.649TyrThr: 1.649 ± 0.021	1.643TyrVal: 1.643 ± 0.018	0.476TyrTrp: 0.476 ± 0.009	0.951TyrTyr: 0.951 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12360 proteins (5813542 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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